GCF_900638015.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_LR134483.1 (Listeria grayi)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	cyclic-lactone-autoinducer	24,379	45,135
Region 2	lanthipeptide-class-ii,cyclic-lactone-autoinducer	340,859	372,102
Region 3	T3PKS,HR-T2PKS	1,121,293	1,175,732
Region 4	terpene-precursor	1,289,853	1,310,734
Region 5	terpene	1,588,819	1,609,667	Low	citrulline	other:other

NZ_LR134483.1 - Region 1 - cyclic-lactone-autoinducer

Download region GenBank file

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Location: 24,379 - 45,135 nt. (total: 20,757 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: glycosyltransferase phosphotransferase

EL241_RS00110: Glucose-specific phosphotransferase enzyme IIA

smcogs: SMCOG1145: Glucose-specific phosphotransferase enzyme IIA

EL241_RS00135: glycosyl transferase group 1

smcogs: SMCOG1045: glycosyl transferase group 1

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002667.2	0.37	ribosomal	estericin A	Clostridium estertheticum
BGC0000881.3	0.33	other (other)	toyocamycin	Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0001808.5	0.33	other (other)	toyocamycin	Streptomyces diastatochromogenes
BGC0000879.5	0.27	other (other)	toyocamycin, sangivamycin	Streptomyces rimosus
BGC0001110.5	0.24	NRPS, PKS	psymberin, irciniastatin B	uncultured bacterium psy1
BGC0001818.4	0.21	NRPS	vazabitide A	Streptomyces sp. SANK 60404
BGC0002571.2	0.20	NRPS	pyoverdine DC3000	Pseudomonas syringae pv. tomato str. DC3000
BGC0001370.4	0.20	NRPS	lipopeptide 8D1-1, lipopeptide 8D1-2	Streptomyces rochei
BGC0002282.2	0.20	other (other)	formycin A	Streptomyces kaniharaensis
BGC0002039.3	0.20	other (other)	coformycin, formycin A	Nocardia interforma ATCC 21072

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002667.2	0.37	ribosomal	estericin A	Clostridium estertheticum
BGC0000881.3	0.33	other (other)	toyocamycin	Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0001808.5	0.33	other (other)	toyocamycin	Streptomyces diastatochromogenes
BGC0000879.5	0.27	other (other)	toyocamycin, sangivamycin	Streptomyces rimosus
BGC0001110.5	0.24	NRPS, PKS	psymberin, irciniastatin B	uncultured bacterium psy1
BGC0001818.4	0.21	NRPS	vazabitide A	Streptomyces sp. SANK 60404
BGC0002571.2	0.20	NRPS	pyoverdine DC3000	Pseudomonas syringae pv. tomato str. DC3000
BGC0001370.4	0.20	NRPS	lipopeptide 8D1-1, lipopeptide 8D1-2	Streptomyces rochei
BGC0002282.2	0.20	other (other)	formycin A	Streptomyces kaniharaensis
BGC0002039.3	0.20	other (other)	coformycin, formycin A	Nocardia interforma ATCC 21072

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 25.88 out of 25.88

Confidence: strong

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.99 out of 26.06

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 20.85 out of 24.78

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 21.11 out of 24.78

Confidence: medium

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 20.60 out of 25.88

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.63 out of 28.19

Confidence: medium

Additional weak hits (4):

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.15 out of 29.25

Confidence: weak

HipB

Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 22.53 out of 33.73

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.98 out of 29.38

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 23.54 out of 33.14

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
LexA variant 2	Repressor of DNA damage response
MogR	Repressor of flagellar motility genes
PsrA	Oleic acid responsive regulator
ZuR variant 1	Zinc-responsive repressor

NZ_LR134483.1 - Region 2 - cyclic-lactone-autoinducer,lanthipeptide-class-ii

Download region GenBank file

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Location: 340,859 - 372,102 nt. (total: 31,244 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Lyases: cyclase

EL241_RS01730: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

EL241_RS01745: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000517.4	0.46	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000554.4	0.42	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000552.3	0.41	ribosomal	SmbA, SmbB	Streptococcus mutans
BGC0002110.3	0.40	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0000525.5	0.39	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0001555.4	0.39	ribosomal	colicin V	Escherichia coli chi7122
BGC0002005.2	0.38	ribosomal	RaxX	Xanthomonas oryzae pv. oryzae
BGC0001787.3	0.37	ribosomal	suicin 3908	Streptococcus suis
BGC0000590.5	0.37	ribosomal	microcin N	Escherichia coli
BGC0001229.4	0.37	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000517.4	0.57	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000552.3	0.56	ribosomal	SmbA, SmbB	Streptococcus mutans
BGC0000554.4	0.56	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0002110.3	0.55	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0000525.5	0.54	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0001229.4	0.53	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000497.3	0.53	ribosomal	BHT-Aα, BHT-Aβ	Streptococcus ratti
BGC0000516.4	0.52	ribosomal	geobacillin II	Geobacillus thermodenitrificans
BGC0001555.4	0.51	ribosomal	colicin V	Escherichia coli chi7122
BGC0001311.5	0.51	ribosomal	flavecins	Ruminococcus flavefaciens FD-1

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for EL241_RS01730

EL241_RS01720

Leader:

MEKKEWEKTAQIVQEGFLQEVEEQEIGEESGGA

Core:

WWNVSKNLGNKGRICTLTKECQSMCN

Core with dehydrations:

WWNVDhaKNLGNKGRICysDhbLDhbKECysQDhaMCysN

antiSMASH-DB 4.0 matches for EL241_RS01720

100.0%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS01720_lanthipeptide

Lanthipeptides: EL241_RS01720_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMCN

65.5%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide

Lanthipeptides: EG886_RS06305_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMCN

WWN+S +LGN GR CTLTKECQ CN

WWNISCHLGNTGRFCTLTKECQPNCN

62.1%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06310_lanthipeptide

Lanthipeptides: EG886_RS06310_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMCN

WWN+S +LGN G+ CTLTKECQ CN

WWNISCHLGNTGQFCTLTKECQPSCN

with 101 more sequence matches

Only the first 10 are displayed here.

60.7%

NC_021362.1and 29 others:

NC_021362.1 Lanthipeptides: BALI_RS00925_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptide

Lanthipeptides: BALI_RS00925_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMC

W+N+S LGNKG+ CTLTKECQ C

WYNISCQLGNKGQWCTLTKECQRSC

60.7%

NZ_CP006058.1and 23 others:

NZ_CP006058.1 Lanthipeptides: BAMY6639_RS13800_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptide

Lanthipeptides: BAMY6639_RS13800_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMCN

W+++S LGNKG CTLT ECQS CN

WYDISCKLGNKGAWCTLTVECQSSCN

60.7%

NZ_CP063276.1and 1 other:

NZ_CP063276.1 Lanthipeptides: IM743_RS02795_lanthipeptide

Lanthipeptides: IM743_RS02795_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMCN

W++VS LGNKG CTLT ECQ+ CN

WYDVSCRLGNKGAWCTLTVECQNNCN

60.7%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS01725_lanthipeptide

Lanthipeptides: EL241_RS01725_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMC

W ++SK+LGNKG +CTLTKECQ +C

WKDLSKSLGNKGYVCTLTKECQKLC

59.3%

NZ_CP025249.1and 1 other:

NZ_CP025249.1 Lanthipeptides: CWT12_RS00385_lanthipeptide

Lanthipeptides: CWT12_RS00385_lanthipeptide

VSKNLGNKGRICTLTKECQSMCN

+S+ LGN G +CTLTKECQ MCN

LSRKLGNTGYVCTLTKECQRMCN

57.1%

NZ_FOBE01000018.1:

Lanthipeptides: BMW61_RS13085_lanthipeptide

WWN-VSKNLGNKGRICTLTKECQSMCN

W++ +S LGN+G CTLTKECQ+ CN

WYSEMSAALGNRGSYCTLTKECQACCN

53.8%

NZ_CP050134.2and 3 others:

NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS10565_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptide

Lanthipeptides: HBA49_RS00770_lanthipeptide

VSKNLGNKGRICTLTKECQSMCN

+S+ LGN GR CT+TKEC CN

LSRLLGNNGRWCTITKECMPSCN

53.3%

NZ_LT985747.1and 1 other:

NZ_LT985747.1 Lanthipeptides: C8268_RS00165_lanthipeptide

Lanthipeptides: C8268_RS00165_lanthipeptide

WNVSKNLGNKGRICTLTKECQSMCN

+ +S LGNKG CTLTKECQ CN

FTLSDYLGNKGGWCTLTKECQRSCN

53.3%

NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21845_lanthipeptide

Lanthipeptides: CN325_RS21845_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMCN

WWNVS +LGN G+ CT +KEC CN

WWNVSCHLGNDGKYCTASKECMPTCN

51.7%

NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21835_lanthipeptide

Lanthipeptides: CN325_RS21835_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMC

+WN+S +LGN G +CTLTKEC+ C

FWNISCHLGNDGSVCTLTKECRPAC

MIBiG 4.0 matches for EL241_RS01720

57.1%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

WWNVSKNLGNKGRICTLTKECQSMCN

W+N+S LGNKG CTLT EC CN

WYNISCRLGNKGAYCTLTVECMPSCN

50.0%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

WNVSKNLGNKGRICTLTKECQSMCN

+++S LGN G CTLTKECQ CN

FSLSNALGNNGGWCTLTKECQPNCN

23.1%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTLTKECQSMCN

CTL+KECQ CN

CTLSKECQPNCN

EL241_RS01725

Leader:

MTKKEYGLQRMSQLDQRDFLKEIEEHEKQNQVSGG

Core:

WGWKDLSKSLGNKGYVCTLTKECQKLCR

Core with dehydrations:

WGWKDLDhaKDhaLGNKGYVCysDhbLDhbKECysQKLCysR

antiSMASH-DB 4.0 matches for EL241_RS01725

100.0%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS01725_lanthipeptide

Lanthipeptides: EL241_RS01725_lanthipeptide

WGWKDLSKSLGNKGYVCTLTKECQKLCR

60.7%

NZ_CP025249.1and 1 other:

NZ_CP025249.1 Lanthipeptides: CWT12_RS00385_lanthipeptide

Lanthipeptides: CWT12_RS00385_lanthipeptide

LSKSLGNKGYVCTLTKECQKLC

LS+ LGN GYVCTLTKECQ++C

LSRKLGNTGYVCTLTKECQRMC

60.7%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS01720_lanthipeptide

Lanthipeptides: EL241_RS01720_lanthipeptide

WKDLSKSLGNKGYVCTLTKECQKLC

W ++SK+LGNKG +CTLTKECQ +C

WWNVSKNLGNKGRICTLTKECQSMC

with 101 more sequence matches

Only the first 10 are displayed here.

60.0%

NZ_CKMQ01000043.1and 10 others:

NZ_CKMQ01000043.1 Lanthipeptides: AE832_RS11585_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: AD782_RS11690_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: AD782_RS11690_lanthipeptideNZ_FIXU01000003.1 Lanthipeptides: A1M11_RS11670_lanthipeptideNZ_FIXU01000003.1 Lanthipeptides: A1M11_RS11670_lanthipeptideNZ_LR216041.1 Lanthipeptides: E0F00_RS05465_lanthipeptideNZ_LR216046.1 Lanthipeptides: E0E82_RS05980_lanthipeptideNZ_LR216046.1 Lanthipeptides: E0E82_RS05980_lanthipeptideNZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00170_lanthipeptideNZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00170_lanthipeptide

Lanthipeptides: AE832_RS11585_lanthipeptide

GWKDLS---KSLGNKGYVCTLTKECQKLCR

GW LS ++LGNKG VCT T ECQ CR

GWAQLSFISEALGNKGAVCTGTIECQNNCR

57.1%

NC_021362.1and 29 others:

Lanthipeptides: BALI_RS00925_lanthipeptide

WKDLSKSLGNKGYVCTLTKECQKLCR

W ++S LGNKG CTLTKECQ+ C+

WYNISCQLGNKGQWCTLTKECQRSCK

57.1%

NZ_CP006058.1and 23 others:

Lanthipeptides: BAMY6639_RS13800_lanthipeptide

GWKDLSKSLGNKGYVCTLTKECQKLCR

W D+S LGNKG CTLT ECQ C

AWYDISCKLGNKGAWCTLTVECQSSCN

57.1%

NZ_CP063276.1and 1 other:

NZ_CP063276.1 Lanthipeptides: IM743_RS02795_lanthipeptide

Lanthipeptides: IM743_RS02795_lanthipeptide

GWKDLSKSLGNKGYVCTLTKECQKLCR

W D+S LGNKG CTLT ECQ C

AWYDVSCRLGNKGAWCTLTVECQNNCN

57.1%

NZ_KE384107.1:

Lanthipeptides: G586_RS23925_lanthipeptide

WKDLSKSLGNKGYVCTLTKECQKLCR

+ DLS SLGN+G CT+TKECQ C

YADLSASLGNRGSYCTITKECQACCN

53.3%

NZ_CP043317.1and 1 other:

NZ_CP043317.1 Lanthipeptides: FYC74_RS17680_lanthipeptide

Lanthipeptides: FYC74_RS17680_lanthipeptide

LSKSLGNKGYVCTLTKECQKLCR

LS SLGN G CTLTKECQ C

LSDSLGNHGGWCTLTKECQPNCS

53.3%

NZ_LT985747.1and 1 other:

NZ_LT985747.1 Lanthipeptides: C8268_RS00165_lanthipeptide

Lanthipeptides: C8268_RS00165_lanthipeptide

LSKSLGNKGYVCTLTKECQKLCR

LS LGNKG CTLTKECQ+ C

LSDYLGNKGGWCTLTKECQRSCN

51.7%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06310_lanthipeptide

Lanthipeptides: EG886_RS06310_lanthipeptide

WKDLSKSLGNKGYVCTLTKECQKLCR

W ++S LGN G CTLTKECQ C

WWNISCHLGNTGQFCTLTKECQPSCN

51.7%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide

Lanthipeptides: EG886_RS06305_lanthipeptide

WKDLSKSLGNKGYVCTLTKECQKLCR

W ++S LGN G CTLTKECQ C

WWNISCHLGNTGRFCTLTKECQPNCN

50.0%

NZ_AKXV01000031.1and 4 others:

NZ_AKXV01000031.1 Lanthipeptides: Y19_RS0109895_lanthipeptideNZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13545_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide

Lanthipeptides: Y19_RS0109895_lanthipeptide

LSKSLGNKGYVCTLTKECQKLCR

LS LGN+G CTLTKECQ C

LSDFLGNQGGWCTLTKECQPNCN

MIBiG 4.0 matches for EL241_RS01725

50.0%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

GWKDLSKSLGNKGYVCTLTKECQKLCR

W ++S LGNKG CTLT EC C

AWYNISCRLGNKGAYCTLTVECMPSCN

50.0%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

DLSKSLGNKGYVCTLTKECQKLCR

LS +LGN G CTLTKECQ C

SLSNALGNNGGWCTLTKECQPNCN

20.5%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTLTKECQKLC

CTL+KECQ C

CTLSKECQPNC

EL241_RS13590

Leader:

MTNQKKEVMNEKEQKLEAELRELSSHEDENGG

Core:

FPWTVTVPLSIALCPTAKCTSKCR

Core with dehydrations:

FPWDhbVDhbVPLDhaIALCysPDhbAKCysDhbDhaKCysR

antiSMASH-DB 4.0 matches for EL241_RS13590

100.0%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS13590_lanthipeptide

Lanthipeptides: EL241_RS13590_lanthipeptide

FPWTVTVPLSIALCPTAKCTSKCR

44.8%

NZ_JADPDT010000005.1and 1 other:

NZ_JADPDT010000005.1 Lanthipeptides: I4V19_RS09875_lanthipeptide

Lanthipeptides: I4V19_RS09875_lanthipeptide

VPLSIALCPTAKCTSKC

V SI+LCPT KCTSKC

VEASISLCPTTKCTSKC

42.9%

NZ_CP017762.1and 3 others:

NZ_CP017762.1 Lanthipeptides: BKP57_RS21840_lanthipeptideNZ_CP073011.1 Lanthipeptides: KBP50_RS06730_lanthipeptideNZ_CP073011.1 Lanthipeptides: KBP50_RS06730_lanthipeptide

Lanthipeptides: BKP57_RS21840_lanthipeptide

VPLSIALCPTAKCTSKC

V SIALCPT C+SKC

VAASIALCPTLACSSKC

with 85 more sequence matches

Only the first 10 are displayed here.

42.9%

NZ_CP040417.1and 7 others:

NZ_CP040417.1 Lanthipeptides: FE328_RS09035_lanthipeptideNZ_CP040419.1 Lanthipeptides: FE326_RS02890_lanthipeptideNZ_CP040419.1 Lanthipeptides: FE326_RS02890_lanthipeptideNZ_CP040421.1 Lanthipeptides: FE324_RS02830_lanthipeptideNZ_CP040421.1 Lanthipeptides: FE324_RS02830_lanthipeptideNZ_CP040422.1 Lanthipeptides: FE323_RS02865_lanthipeptideNZ_CP040422.1 Lanthipeptides: FE323_RS02865_lanthipeptide

Lanthipeptides: FE328_RS09035_lanthipeptide

WTVTVPLSIALCPTAKCTSKCR

WT VP+S+A+CP+ KC S R

WTSLVPISLAICPSTKCASITR

41.7%

NZ_CP050134.2and 3 others:

NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS14310_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS13085_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS13085_lanthipeptide

Lanthipeptides: HBA49_RS00775_lanthipeptide

VPLSIALCPTAKCTSKC

+P+SIALCPT +C+ +C

IPISIALCPTTRCSRRC

41.7%

NZ_CP063142.1and 1 other:

NZ_CP063142.1 Lanthipeptides: HPB58_RS21460_lanthipeptide

Lanthipeptides: HPB58_RS21460_lanthipeptide

WTVTVPLSIALCPT

WTVT+P+S+A CPT

WTVTIPISLAACPT

41.4%

NZ_CP042598.1and 3 others:

NZ_CP042598.1 Lanthipeptides: FUT28_RS13815_lanthipeptideNZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11625_lanthipeptideNZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11625_lanthipeptide

Lanthipeptides: FUT28_RS13815_lanthipeptide

VPLSIALCPTAKCTSKC

V SI+LCPT KCTS+C

VDASISLCPTTKCTSQC

40.7%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS18310_lanthipeptide

VTVPLSIALCPTAKCTSKC

+TV +S+++CPT KCTS+C

ITVTISVSMCPTTKCTSQC

40.6%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

TVTVPLSIALCPTAKCTSKC

T+ V +S+ LCPT KCTSKC

TIVVAISVGLCPTTKCTSKC

40.6%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

TVTVPLSIALCPTAKCTSKC

T+ V +S+ LCPT KCTSKC

TIVVGISVGLCPTTKCTSKC

39.3%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: E4J16_RS14990_lanthipeptide

Lanthipeptides: E4J16_RS14990_lanthipeptide

WTVTVPLSIALCPTAKCTSKCR

W + ++ +CPTA CTSKCR

WPCGIGITTTICPTAVCTSKCR

38.7%

NZ_AP026714.1and 21 others:

NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide

Lanthipeptides: PO853_RS06520_lanthipeptide

TVTVPLSIAL--------CPTAKCTSKC

T+T+P+SIA+ CPT+ CT C

TITIPISIAVSGWISDKTCPTSVCTRAC

38.5%

NZ_JFCR01000001.1and 3 others:

NZ_JFCR01000001.1 Lanthipeptides: JQ44_RS10210_lanthipeptideNZ_JUNC01000006.1 Lanthipeptides: ADC63_RS10380_lanthipeptideNZ_JUNC01000006.1 Lanthipeptides: ADC63_RS10380_lanthipeptide

Lanthipeptides: JQ44_RS10210_lanthipeptide

SIALCPTAKCTSKC

S+ALCPT KC+S C

SVALCPTTKCSSAC

MIBiG 4.0 matches for EL241_RS13590

34.6%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

LCPTAKCTSKC

CPT KCTSKC

FCPTTKCTSKC

32.4%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

VTVPLSIALCPTAKCTSKC

V V +S A CPT KCTS+C

VAVGVSAAFCPTTKCTSRC

16.7%

BGC0000553.3 (SSGG_RS09925):

Lanthipeptide: SRO15-2212

LSIALC

LS+ LC

LSVVLC

EL241_RS01765

Leader:

MKKLVINLFEMFGS

Core:

LNVRQCCFLLSDEIEIPDELAE

Core with dehydrations:

LNVRQCysCysFLLDhaDEIEIPDELAE

antiSMASH-DB 4.0 matches for EL241_RS01765

100.0%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS01765_lanthipeptide

Lanthipeptides: EL241_RS01765_lanthipeptide

LNVRQCCFLLSDEIEIPDELAE

21.2%

NZ_LVYL01000010.1and 1 other:

NZ_LVYL01000010.1 Lanthipeptides: A3863_RS05845_lanthipeptide

Lanthipeptides: A3863_RS05845_lanthipeptide

VRQCCFLLSDEIEIPDELAE

+ C FL ++ E+P+EL +

INSCTFLFHED-EVPEELQK

20.4%

NZ_CP013210.1:

Lanthipeptides: AS589_RS08105_lanthipeptide

NVRQCCFLLSDEIEIPDELAE

N CC+ L D I PDE A

NGFTCCWCLGDVIVNPDEPAS

with 4 more sequence matches

18.9%

NC_022571.1and 1 other:

NZ_CP016091.1 Lanthipeptides: CLOBY_RS22135_lanthipeptide

Lanthipeptides: CLSA_RS23015_lanthipeptide

VRQCCFLLSDEIEIPDEL

+ +CCF E +IP +L

MEKCCFGGIYETKIPIQL

15.0%

NZ_CBYF010000036.1and 1 other:

NZ_JAMBNC010000014.1 Lanthipeptides: M2T98_RS17575_lanthipeptide

Lanthipeptides: C2S54_RS14310_lanthipeptide

FLLSDEIE

++LSDEIE

YILSDEIE

14.0%

NZ_JAGKQT010000007.1and 1 other:

NZ_JAGKQT010000007.1 Lanthipeptides: J2M30_RS09870_lanthipeptide

Lanthipeptides: J2M30_RS09870_lanthipeptide

VRQCCFLLSDEIEIPDEL

+ C FL ++ E+P+EL

INSCTFLFHED-EVPEEL

9.1%

NZ_LT907978.1:

Lanthipeptides: allorf_2780940_2781146_lanthipeptide

QCCFLLSDEIEIPD

+C +LLS ++ + D

ECLYLLSTDVSLSD

allorf_0347033_0347134

Leader:

MGISSFRLYFLRNIFAI

Core:

NCSSYIQVFSYYFVLN

Core with dehydrations:

NCysDhaDhaYIQVFDhaYYFVLN

antiSMASH-DB 4.0 matches for allorf_0347033_0347134

100.0%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: allorf_0347033_0347134_lanthipeptide

Lanthipeptides: allorf_0347033_0347134_lanthipeptide

NCSSYIQVFSYYFVLN

20.8%

NZ_CP020040.1:

Lanthipeptides: allorf_278451_278618_lanthipeptide

CSSYIQVFSYYFVLN

CS I++ +FV+

CSRLIRLGGIWFVIG

Lanthipeptide(s) for EL241_RS01745

EL241_RS01720

Leader:

MEKKEWEKTAQIVQEGFLQEVEEQEIGEESGGA

Core:

WWNVSKNLGNKGRICTLTKECQSMCN

Core with dehydrations:

WWNVDhaKNLGNKGRICysDhbLDhbKECysQDhaMCysN

antiSMASH-DB 4.0 matches for EL241_RS01720

100.0%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS01720_lanthipeptide

Lanthipeptides: EL241_RS01720_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMCN

65.5%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide

Lanthipeptides: EG886_RS06305_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMCN

WWN+S +LGN GR CTLTKECQ CN

WWNISCHLGNTGRFCTLTKECQPNCN

62.1%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06310_lanthipeptide

Lanthipeptides: EG886_RS06310_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMCN

WWN+S +LGN G+ CTLTKECQ CN

WWNISCHLGNTGQFCTLTKECQPSCN

with 101 more sequence matches

Only the first 10 are displayed here.

60.7%

NC_021362.1and 29 others:

Lanthipeptides: BALI_RS00925_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMC

W+N+S LGNKG+ CTLTKECQ C

WYNISCQLGNKGQWCTLTKECQRSC

60.7%

NZ_CP006058.1and 23 others:

Lanthipeptides: BAMY6639_RS13800_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMCN

W+++S LGNKG CTLT ECQS CN

WYDISCKLGNKGAWCTLTVECQSSCN

60.7%

NZ_CP063276.1and 1 other:

NZ_CP063276.1 Lanthipeptides: IM743_RS02795_lanthipeptide

Lanthipeptides: IM743_RS02795_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMCN

W++VS LGNKG CTLT ECQ+ CN

WYDVSCRLGNKGAWCTLTVECQNNCN

60.7%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS01725_lanthipeptide

Lanthipeptides: EL241_RS01725_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMC

W ++SK+LGNKG +CTLTKECQ +C

WKDLSKSLGNKGYVCTLTKECQKLC

59.3%

NZ_CP025249.1and 1 other:

NZ_CP025249.1 Lanthipeptides: CWT12_RS00385_lanthipeptide

Lanthipeptides: CWT12_RS00385_lanthipeptide

VSKNLGNKGRICTLTKECQSMCN

+S+ LGN G +CTLTKECQ MCN

LSRKLGNTGYVCTLTKECQRMCN

57.1%

NZ_FOBE01000018.1:

Lanthipeptides: BMW61_RS13085_lanthipeptide

WWN-VSKNLGNKGRICTLTKECQSMCN

W++ +S LGN+G CTLTKECQ+ CN

WYSEMSAALGNRGSYCTLTKECQACCN

53.8%

NZ_CP050134.2and 3 others:

NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS10565_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptide

Lanthipeptides: HBA49_RS00770_lanthipeptide

VSKNLGNKGRICTLTKECQSMCN

+S+ LGN GR CT+TKEC CN

LSRLLGNNGRWCTITKECMPSCN

53.3%

NZ_LT985747.1and 1 other:

NZ_LT985747.1 Lanthipeptides: C8268_RS00165_lanthipeptide

Lanthipeptides: C8268_RS00165_lanthipeptide

WNVSKNLGNKGRICTLTKECQSMCN

+ +S LGNKG CTLTKECQ CN

FTLSDYLGNKGGWCTLTKECQRSCN

53.3%

NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21845_lanthipeptide

Lanthipeptides: CN325_RS21845_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMCN

WWNVS +LGN G+ CT +KEC CN

WWNVSCHLGNDGKYCTASKECMPTCN

51.7%

NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21835_lanthipeptide

Lanthipeptides: CN325_RS21835_lanthipeptide

WWNVSKNLGNKGRICTLTKECQSMC

+WN+S +LGN G +CTLTKEC+ C

FWNISCHLGNDGSVCTLTKECRPAC

MIBiG 4.0 matches for EL241_RS01720

57.1%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

WWNVSKNLGNKGRICTLTKECQSMCN

W+N+S LGNKG CTLT EC CN

WYNISCRLGNKGAYCTLTVECMPSCN

50.0%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

WNVSKNLGNKGRICTLTKECQSMCN

+++S LGN G CTLTKECQ CN

FSLSNALGNNGGWCTLTKECQPNCN

23.1%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTLTKECQSMCN

CTL+KECQ CN

CTLSKECQPNCN

EL241_RS01725

Leader:

MTKKEYGLQRMSQLDQRDFLKEIEEHEKQNQVSGG

Core:

WGWKDLSKSLGNKGYVCTLTKECQKLCR

Core with dehydrations:

WGWKDLDhaKDhaLGNKGYVCysDhbLDhbKECysQKLCysR

antiSMASH-DB 4.0 matches for EL241_RS01725

100.0%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS01725_lanthipeptide

Lanthipeptides: EL241_RS01725_lanthipeptide

WGWKDLSKSLGNKGYVCTLTKECQKLCR

60.7%

NZ_CP025249.1and 1 other:

NZ_CP025249.1 Lanthipeptides: CWT12_RS00385_lanthipeptide

Lanthipeptides: CWT12_RS00385_lanthipeptide

LSKSLGNKGYVCTLTKECQKLC

LS+ LGN GYVCTLTKECQ++C

LSRKLGNTGYVCTLTKECQRMC

60.7%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS01720_lanthipeptide

Lanthipeptides: EL241_RS01720_lanthipeptide

WKDLSKSLGNKGYVCTLTKECQKLC

W ++SK+LGNKG +CTLTKECQ +C

WWNVSKNLGNKGRICTLTKECQSMC

with 101 more sequence matches

Only the first 10 are displayed here.

60.0%

NZ_CKMQ01000043.1and 10 others:

Lanthipeptides: AE832_RS11585_lanthipeptide

GWKDLS---KSLGNKGYVCTLTKECQKLCR

GW LS ++LGNKG VCT T ECQ CR

GWAQLSFISEALGNKGAVCTGTIECQNNCR

57.1%

NC_021362.1and 29 others:

Lanthipeptides: BALI_RS00925_lanthipeptide

WKDLSKSLGNKGYVCTLTKECQKLCR

W ++S LGNKG CTLTKECQ+ C+

WYNISCQLGNKGQWCTLTKECQRSCK

57.1%

NZ_CP006058.1and 23 others:

Lanthipeptides: BAMY6639_RS13800_lanthipeptide

GWKDLSKSLGNKGYVCTLTKECQKLCR

W D+S LGNKG CTLT ECQ C

AWYDISCKLGNKGAWCTLTVECQSSCN

57.1%

NZ_CP063276.1and 1 other:

NZ_CP063276.1 Lanthipeptides: IM743_RS02795_lanthipeptide

Lanthipeptides: IM743_RS02795_lanthipeptide

GWKDLSKSLGNKGYVCTLTKECQKLCR

W D+S LGNKG CTLT ECQ C

AWYDVSCRLGNKGAWCTLTVECQNNCN

57.1%

NZ_KE384107.1:

Lanthipeptides: G586_RS23925_lanthipeptide

WKDLSKSLGNKGYVCTLTKECQKLCR

+ DLS SLGN+G CT+TKECQ C

YADLSASLGNRGSYCTITKECQACCN

53.3%

NZ_CP043317.1and 1 other:

NZ_CP043317.1 Lanthipeptides: FYC74_RS17680_lanthipeptide

Lanthipeptides: FYC74_RS17680_lanthipeptide

LSKSLGNKGYVCTLTKECQKLCR

LS SLGN G CTLTKECQ C

LSDSLGNHGGWCTLTKECQPNCS

53.3%

NZ_LT985747.1and 1 other:

NZ_LT985747.1 Lanthipeptides: C8268_RS00165_lanthipeptide

Lanthipeptides: C8268_RS00165_lanthipeptide

LSKSLGNKGYVCTLTKECQKLCR

LS LGNKG CTLTKECQ+ C

LSDYLGNKGGWCTLTKECQRSCN

51.7%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06310_lanthipeptide

Lanthipeptides: EG886_RS06310_lanthipeptide

WKDLSKSLGNKGYVCTLTKECQKLCR

W ++S LGN G CTLTKECQ C

WWNISCHLGNTGQFCTLTKECQPSCN

51.7%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide

Lanthipeptides: EG886_RS06305_lanthipeptide

WKDLSKSLGNKGYVCTLTKECQKLCR

W ++S LGN G CTLTKECQ C

WWNISCHLGNTGRFCTLTKECQPNCN

50.0%

NZ_AKXV01000031.1and 4 others:

Lanthipeptides: Y19_RS0109895_lanthipeptide

LSKSLGNKGYVCTLTKECQKLCR

LS LGN+G CTLTKECQ C

LSDFLGNQGGWCTLTKECQPNCN

MIBiG 4.0 matches for EL241_RS01725

50.0%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

GWKDLSKSLGNKGYVCTLTKECQKLCR

W ++S LGNKG CTLT EC C

AWYNISCRLGNKGAYCTLTVECMPSCN

50.0%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

DLSKSLGNKGYVCTLTKECQKLCR

LS +LGN G CTLTKECQ C

SLSNALGNNGGWCTLTKECQPNCN

20.5%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTLTKECQKLC

CTL+KECQ C

CTLSKECQPNC

EL241_RS13590

Leader:

MTNQKKEVMNEKEQKLEAELRELSSHEDENGG

Core:

FPWTVTVPLSIALCPTAKCTSKCR

Core with dehydrations:

FPWDhbVDhbVPLDhaIALCysPDhbAKCysDhbDhaKCysR

antiSMASH-DB 4.0 matches for EL241_RS13590

100.0%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS13590_lanthipeptide

Lanthipeptides: EL241_RS13590_lanthipeptide

FPWTVTVPLSIALCPTAKCTSKCR

44.8%

NZ_JADPDT010000005.1and 1 other:

NZ_JADPDT010000005.1 Lanthipeptides: I4V19_RS09875_lanthipeptide

Lanthipeptides: I4V19_RS09875_lanthipeptide

VPLSIALCPTAKCTSKC

V SI+LCPT KCTSKC

VEASISLCPTTKCTSKC

42.9%

NZ_CP017762.1and 3 others:

NZ_CP017762.1 Lanthipeptides: BKP57_RS21840_lanthipeptideNZ_CP073011.1 Lanthipeptides: KBP50_RS06730_lanthipeptideNZ_CP073011.1 Lanthipeptides: KBP50_RS06730_lanthipeptide

Lanthipeptides: BKP57_RS21840_lanthipeptide

VPLSIALCPTAKCTSKC

V SIALCPT C+SKC

VAASIALCPTLACSSKC

with 85 more sequence matches

Only the first 10 are displayed here.

42.9%

NZ_CP040417.1and 7 others:

Lanthipeptides: FE328_RS09035_lanthipeptide

WTVTVPLSIALCPTAKCTSKCR

WT VP+S+A+CP+ KC S R

WTSLVPISLAICPSTKCASITR

41.7%

NZ_CP050134.2and 3 others:

NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS14310_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS13085_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS13085_lanthipeptide

Lanthipeptides: HBA49_RS00775_lanthipeptide

VPLSIALCPTAKCTSKC

+P+SIALCPT +C+ +C

IPISIALCPTTRCSRRC

41.7%

NZ_CP063142.1and 1 other:

NZ_CP063142.1 Lanthipeptides: HPB58_RS21460_lanthipeptide

Lanthipeptides: HPB58_RS21460_lanthipeptide

WTVTVPLSIALCPT

WTVT+P+S+A CPT

WTVTIPISLAACPT

41.4%

NZ_CP042598.1and 3 others:

NZ_CP042598.1 Lanthipeptides: FUT28_RS13815_lanthipeptideNZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11625_lanthipeptideNZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11625_lanthipeptide

Lanthipeptides: FUT28_RS13815_lanthipeptide

VPLSIALCPTAKCTSKC

V SI+LCPT KCTS+C

VDASISLCPTTKCTSQC

40.7%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS18310_lanthipeptide

VTVPLSIALCPTAKCTSKC

+TV +S+++CPT KCTS+C

ITVTISVSMCPTTKCTSQC

40.6%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

TVTVPLSIALCPTAKCTSKC

T+ V +S+ LCPT KCTSKC

TIVVAISVGLCPTTKCTSKC

40.6%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

TVTVPLSIALCPTAKCTSKC

T+ V +S+ LCPT KCTSKC

TIVVGISVGLCPTTKCTSKC

39.3%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: E4J16_RS14990_lanthipeptide

Lanthipeptides: E4J16_RS14990_lanthipeptide

WTVTVPLSIALCPTAKCTSKCR

W + ++ +CPTA CTSKCR

WPCGIGITTTICPTAVCTSKCR

38.7%

NZ_AP026714.1and 21 others:

Lanthipeptides: PO853_RS06520_lanthipeptide

TVTVPLSIAL--------CPTAKCTSKC

T+T+P+SIA+ CPT+ CT C

TITIPISIAVSGWISDKTCPTSVCTRAC

38.5%

NZ_JFCR01000001.1and 3 others:

NZ_JFCR01000001.1 Lanthipeptides: JQ44_RS10210_lanthipeptideNZ_JUNC01000006.1 Lanthipeptides: ADC63_RS10380_lanthipeptideNZ_JUNC01000006.1 Lanthipeptides: ADC63_RS10380_lanthipeptide

Lanthipeptides: JQ44_RS10210_lanthipeptide

SIALCPTAKCTSKC

S+ALCPT KC+S C

SVALCPTTKCSSAC

MIBiG 4.0 matches for EL241_RS13590

34.6%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

LCPTAKCTSKC

CPT KCTSKC

FCPTTKCTSKC

32.4%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

VTVPLSIALCPTAKCTSKC

V V +S A CPT KCTS+C

VAVGVSAAFCPTTKCTSRC

16.7%

BGC0000553.3 (SSGG_RS09925):

Lanthipeptide: SRO15-2212

LSIALC

LS+ LC

LSVVLC

EL241_RS01765

Leader:

MKKLVINLFEMFGS

Core:

LNVRQCCFLLSDEIEIPDELAE

Core with dehydrations:

LNVRQCysCysFLLDhaDEIEIPDELAE

antiSMASH-DB 4.0 matches for EL241_RS01765

100.0%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS01765_lanthipeptide

Lanthipeptides: EL241_RS01765_lanthipeptide

LNVRQCCFLLSDEIEIPDELAE

21.2%

NZ_LVYL01000010.1and 1 other:

NZ_LVYL01000010.1 Lanthipeptides: A3863_RS05845_lanthipeptide

Lanthipeptides: A3863_RS05845_lanthipeptide

VRQCCFLLSDEIEIPDELAE

+ C FL ++ E+P+EL +

INSCTFLFHED-EVPEELQK

20.4%

NZ_CP013210.1:

Lanthipeptides: AS589_RS08105_lanthipeptide

NVRQCCFLLSDEIEIPDELAE

N CC+ L D I PDE A

NGFTCCWCLGDVIVNPDEPAS

with 4 more sequence matches

18.9%

NC_022571.1and 1 other:

NZ_CP016091.1 Lanthipeptides: CLOBY_RS22135_lanthipeptide

Lanthipeptides: CLSA_RS23015_lanthipeptide

VRQCCFLLSDEIEIPDEL

+ +CCF E +IP +L

MEKCCFGGIYETKIPIQL

15.0%

NZ_CBYF010000036.1and 1 other:

NZ_JAMBNC010000014.1 Lanthipeptides: M2T98_RS17575_lanthipeptide

Lanthipeptides: C2S54_RS14310_lanthipeptide

FLLSDEIE

++LSDEIE

YILSDEIE

14.0%

NZ_JAGKQT010000007.1and 1 other:

NZ_JAGKQT010000007.1 Lanthipeptides: J2M30_RS09870_lanthipeptide

Lanthipeptides: J2M30_RS09870_lanthipeptide

VRQCCFLLSDEIEIPDEL

+ C FL ++ E+P+EL

INSCTFLFHED-EVPEEL

9.1%

NZ_LT907978.1:

Lanthipeptides: allorf_2780940_2781146_lanthipeptide

QCCFLLSDEIEIPD

+C +LLS ++ + D

ECLYLLSTDVSLSD

allorf_0347033_0347134

Leader:

MGISSFRLYFLRNIFAI

Core:

NCSSYIQVFSYYFVLN

Core with dehydrations:

NCysDhaDhaYIQVFDhaYYFVLN

antiSMASH-DB 4.0 matches for allorf_0347033_0347134

100.0%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: allorf_0347033_0347134_lanthipeptide

Lanthipeptides: allorf_0347033_0347134_lanthipeptide

NCSSYIQVFSYYFVLN

20.8%

NZ_CP020040.1:

Lanthipeptides: allorf_278451_278618_lanthipeptide

CSSYIQVFSYYFVLN

CS I++ +FV+

CSRLIRLGGIWFVIG

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

Binding sites found:

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 21.57 out of 26.33

Confidence: medium

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.05 out of 21.55

Confidence: medium

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.32 out of 21.55

Confidence: medium

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 23.92 out of 29.65

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 21.59 out of 24.78

Confidence: medium

RutR

Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 21.97 out of 26.85

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 20.84 out of 24.78

Confidence: medium

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.58 out of 21.84

Confidence: medium

AbrC3

Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 15.96 out of 18.16

Confidence: strong

Additional weak hits (3):

MntR

Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 24.85 out of 39.62

Confidence: weak

HipB

Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 22.53 out of 33.73

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.16 out of 29.25

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

EL241_RS01720 - Class II

Cleavage pHMM score: -3.70

RODEO score: 0

Monoisotopic mass: 2940.4 Da

Molecular weight: 2942.4 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2960.4 Da N = 1

EL241_RS01725 - Class II

Cleavage pHMM score: -3.40

RODEO score: 0

Monoisotopic mass: 3171.6 Da

Molecular weight: 3173.7 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3191.7 Da N = 1

EL241_RS13590 - Class II

Cleavage pHMM score: -3.70

RODEO score: 0

Monoisotopic mass: 2513.4 Da

Molecular weight: 2515.0 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2533.1 Da N = 1; 2551.1 Da N = 2; 2569.1 Da N = 3

EL241_RS01765 - Class II

Cleavage pHMM score: -3.80

RODEO score: 0

Monoisotopic mass: 2530.2 Da

Molecular weight: 2531.9 Da

Number of bridges: 1

allorf_0347033_0347134 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 1891.9 Da

Molecular weight: 1893.1 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1911.1 Da N = 1; 1929.1 Da N = 2

EL241_RS01720 - Class II

Cleavage pHMM score: -3.70

RODEO score: 0

Monoisotopic mass: 2940.4 Da

Molecular weight: 2942.4 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2960.4 Da N = 1

EL241_RS01725 - Class II

Cleavage pHMM score: -3.40

RODEO score: 0

Monoisotopic mass: 3171.6 Da

Molecular weight: 3173.7 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3191.7 Da N = 1

EL241_RS13590 - Class II

Cleavage pHMM score: -3.70

RODEO score: 0

Monoisotopic mass: 2513.4 Da

Molecular weight: 2515.0 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2533.1 Da N = 1; 2551.1 Da N = 2; 2569.1 Da N = 3

EL241_RS01765 - Class II

Cleavage pHMM score: -3.80

RODEO score: 0

Monoisotopic mass: 2530.2 Da

Molecular weight: 2531.9 Da

Number of bridges: 1

allorf_0347033_0347134 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 1891.9 Da

Molecular weight: 1893.1 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1911.1 Da N = 1; 1929.1 Da N = 2

TFBS definitions

Regulator	Description
ANR	Anaerobic transcriptional regulator
AbrC3	Antibiotic production activator
ArcA	Repressor of carbon oxidation
LexA variant 1	Repressor of DNA damage response
LexA variant 2	Repressor of DNA damage response
MexT	Global virulence regulator
RutR	Regulator of the pyrimidine and purine metabolism

NZ_LR134483.1 - Region 3 - HR-T2PKS,T3PKS

Download region GenBank file

Download region SVG

Location: 1,121,293 - 1,175,732 nt. (total: 54,440 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)
HR-T2PKS: (hr-t2pks-ksa and (t2fas or APE_KS2 or ketoacyl-synt))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase oxidoreductase reductase

EL241_RS05410: pyridine nucleotide-disulfide oxidoreductase

smcogs: SMCOG1175: pyridine nucleotide-disulfide oxidoreductase

EL241_RS05510: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

EL241_RS13795: hydroxymethylglutaryl-CoA reductase

smcogs: SMCOG1187: hydroxymethylglutaryl-CoA reductase

Transferases: PPTase acetyltransferase phosphorylase

EL241_RS05395: thiamine-phosphate pyrophosphorylase

smcogs: SMCOG1280: thiamine-phosphate pyrophosphorylase

EL241_RS13790: acetyl-CoA acetyltransferase

smcogs: SMCOG1124: acetyl-CoA acetyltransferase

EL241_RS13915: 4'-phosphopantetheinyl transferase

smcogs: SMCOG1012: 4'-phosphopantetheinyl transferase

EL241_RS13920: 4'-phosphopantetheinyl transferase

smcogs: SMCOG1012: 4'-phosphopantetheinyl transferase

Hydrolases: peptidase

EL241_RS05555: methionine aminopeptidase

smcogs: SMCOG1172: methionine aminopeptidase

Ligases: synthase

EL241_RS05440: hydroxymethylglutaryl-CoA synthase

smcogs: SMCOG1043: hydroxymethylglutaryl-CoA synthase

EL241_RS05500: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002276.2	0.49	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0000866.5	0.46	other (other)	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0000867.3	0.39	other (other)	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0001197.5	0.36	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0001987.2	0.35	PKS	koreenceine A, koreenceine B, koreenceine C, koreenceine D	Pseudomonas koreensis
BGC0000888.5	0.34	other (other)	bacilysin	Bacillus sp. CS93
BGC0002510.2	0.33	PKS	youssoufene A1, youssoufene B1, youssoufene B2, youssoufene B3, youssoufene B4	Streptomyces sp.
BGC0000231.5	0.32	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0001184.4	0.31	other (other)	bacilysin	Bacillus velezensis FZB42
BGC0000218.5	0.30	PKS	doxorubicin	Streptomyces peucetius

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002276.2	0.58	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0000866.5	0.57	other (other)	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0000867.3	0.52	other (other)	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0001197.5	0.50	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0002510.2	0.49	PKS	youssoufene A1, youssoufene B1, youssoufene B2, youssoufene B3, youssoufene B4	Streptomyces sp.
BGC0001928.2	0.49	other (other)	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0001987.2	0.49	PKS	koreenceine A, koreenceine B, koreenceine C, koreenceine D	Pseudomonas koreensis
BGC0000888.5	0.48	other (other)	bacilysin	Bacillus sp. CS93
BGC0000231.5	0.46	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0001917.4	0.46	PKS	5aTHQ-9i, 5aTHQ-9n, 5aTHQ-10a, STAMs-9i, STAMs-9n	Streptomyces nigrescens

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 24.52 out of 29.25

Confidence: medium

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 18.25 out of 18.46

Confidence: strong

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.82 out of 21.84

Confidence: medium

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.93 out of 30.25

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.38 out of 26.06

Confidence: medium

AbrC3

Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 16.78 out of 18.16

Confidence: strong

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 20.32 out of 23.79

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.53 out of 28.19

Confidence: medium

Additional weak hits (6):

MntR

Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 27.38 out of 39.62

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 22.26 out of 28.14

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.39 out of 29.38

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 25.63 out of 32.74

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.54 out of 29.38

Confidence: weak

LuxO

Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 20.68 out of 26.12

Confidence: weak

Detailed domain annotation

Selected features only

Show module domains

TFBS Finder

TFBS definitions

Regulator	Description
AbrC3	Antibiotic production activator
ColR	Phenol-responsive regulator
IolR	Regulator of the inositol catabolism
MexT	Global virulence regulator
MogR	Repressor of flagellar motility genes
RpoN	Regulator of nitrogen assimilation and virulence
SypG	Regulator of biofilm formation and host colonization
ZuR variant 1	Zinc-responsive repressor

NZ_LR134483.1 - Region 4 - terpene-precursor

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Location: 1,289,853 - 1,310,734 nt. (total: 20,882 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: oxidoreductase

EL241_RS06370: pyridine nucleotide-disulfide oxidoreductase

smcogs: SMCOG1175: pyridine nucleotide-disulfide oxidoreductase

Transferases: carboxylase

EL241_RS06310: acetyl-CoA carboxylase biotin carboxylase

smcogs: SMCOG1090: acetyl-CoA carboxylase biotin carboxylase

Hydrolases: peptidase

EL241_RS06295: methionine aminopeptidase

smcogs: SMCOG1172: methionine aminopeptidase

Ligases: synthase synthetase

EL241_RS06340: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

EL241_RS06350: 1-deoxy-D-xylulose-5-phosphate synthase

smcogs: SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase

EL241_RS06380: 1-deoxy-D-xylulose-5-phosphate synthase

smcogs: SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001535.3	0.69	other (other)	branched-chain fatty acids	Streptomyces filamentosus
BGC0001534.3	0.64	other (other)	branched-chain fatty acids	Streptomyces filamentosus
BGC0002283.2	0.49	terpene	sodorifen	Serratia plymuthica
BGC0001361.3	0.49	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0001736.3	0.44	NRPS	pepteridine A, pepteridine B	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001594.3	0.43	other (other)	fischerindole L	Fischerella muscicola UTEX 1829
BGC0000668.5	0.43	other (other), terpene	12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole	Hapalosiphon welwitschii UTEX B 1830
BGC0002284.3	0.42	other (other)	corynecin III, corynecin I, corynecin II	Rhodococcus sp. H-CA8f

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001535.3	0.69	other (other)	branched-chain fatty acids	Streptomyces filamentosus
BGC0001534.3	0.64	other (other)	branched-chain fatty acids	Streptomyces filamentosus
BGC0002283.2	0.49	terpene	sodorifen	Serratia plymuthica
BGC0001361.3	0.49	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0001736.3	0.44	NRPS	pepteridine A, pepteridine B	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001594.3	0.43	other (other)	fischerindole L	Fischerella muscicola UTEX 1829
BGC0000668.5	0.43	other (other), terpene	12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole	Hapalosiphon welwitschii UTEX B 1830
BGC0002284.3	0.42	other (other)	corynecin III, corynecin I, corynecin II	Rhodococcus sp. H-CA8f

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor		FPP	C15	acyclic	PP

Genes with terpene domains:

EL241_RS06340: PT_FPPS_like

Domain 1 (32 - 293): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:: DMAPP, IPP → FPP

Transcription Factor Binding Sites

Binding sites found:

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 24.13 out of 27.78

Confidence: strong

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.06 out of 26.06

Confidence: medium

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 20.83 out of 26.33

Confidence: medium

Additional weak hits (4):

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.67 out of 26.06

Confidence: weak

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 23.12 out of 31.73

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 21.49 out of 29.65

Confidence: weak

NtrC

Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 21.50 out of 29.72

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
ANR	Anaerobic transcriptional regulator
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
MogR	Repressor of flagellar motility genes

NZ_LR134483.1 - Region 5 - terpene

Download region GenBank file

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Location: 1,588,819 - 1,609,667 nt. (total: 20,849 nt) Show pHMM detection rules used

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase phosphate reductase

EL241_RS07710: N-acetyl-gamma-glutamyl-phosphate reductase

smcogs: SMCOG1219: N-acetyl-gamma-glutamyl-phosphate reductase

EL241_RS07755: dehydrogenase

smcogs: SMCOG1222: dehydrogenase

Transferases: aminotransferase

EL241_RS07725: aminotransferase class V

smcogs: SMCOG1139: aminotransferase class V

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000647.3	0.75	terpene	carotenoid	Rhodobacter sphaeroides
BGC0000645.3	0.49	terpene	carotenoid	Halobacillus halophilus DSM 2266
BGC0000646.5	0.49	terpene	β-carotein	uncultured bacterium
BGC0000656.5	0.47	terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000648.3	0.44	terpene	carotenoid	Myxococcus xanthus
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0000664.5	0.42	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000638.3	0.42	terpene	carotenoid	Pantoea ananatis
BGC0001456.3	0.42	terpene	isorenieratene	Streptomyces argillaceus
BGC0000630.3	0.41	terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000647.3	0.75	terpene	carotenoid	Rhodobacter sphaeroides
BGC0000645.3	0.49	terpene	carotenoid	Halobacillus halophilus DSM 2266
BGC0000646.5	0.49	terpene	β-carotein	uncultured bacterium
BGC0000656.5	0.47	terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000648.3	0.44	terpene	carotenoid	Myxococcus xanthus
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0000664.5	0.42	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000638.3	0.42	terpene	carotenoid	Pantoea ananatis
BGC0001456.3	0.42	terpene	isorenieratene	Streptomyces argillaceus
BGC0000630.3	0.41	terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
triterpene	C30 carotenoid	diapophytoene	C30	acyclic	none

Genes with terpene domains:

EL241_RS07750: PT_phytoene_like

Domain 1 (5 - 280): Prenyltransferase; Phytoene synthase like

Subtype: Diapophytoene synthase

Reactions:: FPP → diapophytoene

Transcription Factor Binding Sites

Binding sites found:

VqsM

Description: Regulator of quorum-sensing signalling systems
Species: Pseudomonas aeruginosa PAO1
Score: 18.25 out of 20.47

Confidence: medium

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57

Confidence: strong

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.50 out of 27.78

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.87 out of 28.19

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.03 out of 28.19

Confidence: medium

Additional weak hits (6):

MntR

Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 25.46 out of 39.62

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.92 out of 26.06

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.75 out of 29.38

Confidence: weak

LuxO

Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 20.68 out of 26.12

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 24.04 out of 28.14

Confidence: weak

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 24.03 out of 31.73

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
FPP	Farnesyl diphosphate

TFBS definitions

Regulator	Description
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
ToxT	Regulator of MSHA biosynthesis
VqsM	Regulator of quorum-sensing signalling systems
ZuR variant 1	Zinc-responsive repressor