GCF_015550805.1 - 2 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_JADNBL010000011.1 (Bifidobacterium longum)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 2.1	lanthipeptide-class-ii	60,864	83,965

NZ_JADNBL010000006.1 (Bifidobacterium longum)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 35.1	terpene-precursor	61,797	82,879

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 2.1	lanthipeptide-class-ii	60,864	83,965
Region 35.1	terpene-precursor	61,797	82,879

No secondary metabolite regions were found in these records:: NZ_JADNBL010000010.1 (Bifidobacterium longum); NZ_JADNBL010000012.1 (Bifidobacterium longum); NZ_JADNBL010000013.1 (Bifidobacterium longum); NZ_JADNBL010000014.1 (Bifidobacterium longum); NZ_JADNBL010000015.1 (Bifidobacterium longum); NZ_JADNBL010000016.1 (Bifidobacterium longum); NZ_JADNBL010000017.1 (Bifidobacterium longum); NZ_JADNBL010000018.1 (Bifidobacterium longum); NZ_JADNBL010000019.1 (Bifidobacterium longum); NZ_JADNBL010000001.1 (Bifidobacterium longum); NZ_JADNBL010000020.1 (Bifidobacterium longum); NZ_JADNBL010000021.1 (Bifidobacterium longum); NZ_JADNBL010000022.1 (Bifidobacterium longum); NZ_JADNBL010000023.1 (Bifidobacterium longum); NZ_JADNBL010000024.1 (Bifidobacterium longum); NZ_JADNBL010000025.1 (Bifidobacterium longum); NZ_JADNBL010000026.1 (Bifidobacterium longum); NZ_JADNBL010000027.1 (Bifidobacterium longum); NZ_JADNBL010000028.1 (Bifidobacterium longum); NZ_JADNBL010000029.1 (Bifidobacterium longum); NZ_JADNBL010000002.1 (Bifidobacterium longum); NZ_JADNBL010000030.1 (Bifidobacterium longum); NZ_JADNBL010000031.1 (Bifidobacterium longum); NZ_JADNBL010000032.1 (Bifidobacterium longum); NZ_JADNBL010000033.1 (Bifidobacterium longum); NZ_JADNBL010000034.1 (Bifidobacterium longum); NZ_JADNBL010000035.1 (Bifidobacterium longum); NZ_JADNBL010000036.1 (Bifidobacterium longum); NZ_JADNBL010000037.1 (Bifidobacterium longum); NZ_JADNBL010000038.1 (Bifidobacterium longum); NZ_JADNBL010000003.1 (Bifidobacterium longum); NZ_JADNBL010000004.1 (Bifidobacterium longum); NZ_JADNBL010000005.1 (Bifidobacterium longum); NZ_JADNBL010000007.1 (Bifidobacterium longum); NZ_JADNBL010000008.1 (Bifidobacterium longum); NZ_JADNBL010000009.1 (Bifidobacterium longum)

Compact view

NZ_JADNBL010000011.1 - Region 1 - lanthipeptide-class-ii

Download region GenBank file

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Location: 60,864 - 83,965 nt. (total: 23,102 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Lyases: cyclase

I2A13_RS07640: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001555.4	0.51	ribosomal	colicin V	Escherichia coli chi7122
BGC0000554.4	0.50	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0002698.2	0.50	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566
BGC0000588.5	0.48	ribosomal	microcin L	Escherichia coli
BGC0000528.5	0.48	ribosomal	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001210.5	0.47	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000504.5	0.46	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000626.3	0.45	ribosomal	thuricin	Bacillus thuringiensis
BGC0000501.3	0.45	ribosomal	catenulipeptin	Catenulispora acidiphila DSM 44928
BGC0000500.5	0.44	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001555.4	0.51	ribosomal	colicin V	Escherichia coli chi7122
BGC0000554.4	0.50	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0002698.2	0.50	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566
BGC0000588.5	0.48	ribosomal	microcin L	Escherichia coli
BGC0000528.5	0.48	ribosomal	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001210.5	0.47	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000504.5	0.46	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000626.3	0.45	ribosomal	thuricin	Bacillus thuringiensis
BGC0000501.3	0.45	ribosomal	catenulipeptin	Catenulispora acidiphila DSM 44928
BGC0000500.5	0.44	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for I2A13_RS07640

I2A13_RS07655

Leader:

MSINEKSIVGESFEDLSAADMAMLTGRNDDGVAPA

Core:

SLSFAVSVLSVSFSACSATVVTRLASCGNCK

Core with dehydrations:

DhaLDhaFAVDhaVLDhaVDhaFDhaACysDhaADhbVVDhbRLADhaCysGNCysK

antiSMASH-DB 4.0 matches for I2A13_RS07655

100.0%

NZ_CP046514.1and 12 others:

NZ_CP083257.1 Lanthipeptides: BCBL_RS08920_lanthipeptideNZ_CP084012.1 Lanthipeptides: LCQ81_RS01125_lanthipeptideNZ_CP084020.1 Lanthipeptides: LCQ52_RS09765_lanthipeptideNZ_GL622638.1 Lanthipeptides: HMPREF0177_RS02885_lanthipeptideNZ_JADMSA010000006.1 Lanthipeptides: I2H42_RS05020_lanthipeptideNZ_JADMUN010000007.1 Lanthipeptides: I1M16_RS07360_lanthipeptideNZ_JADNBL010000011.1 Lanthipeptides: I2A13_RS07655_lanthipeptideNZ_JADPBZ010000019.1 Lanthipeptides: I4V99_RS08285_lanthipeptideNZ_JADPCP010000015.1 Lanthipeptides: I4W34_RS09795_lanthipeptideNZ_JADPFY010000033.1 Lanthipeptides: I4V11_RS10065_lanthipeptideNZ_JAHTKJ010000004.1 Lanthipeptides: KUF58_RS04255_lanthipeptideNZ_SPGO01000021.1 Lanthipeptides: FGQ71_RS09210_lanthipeptide

Lanthipeptides: GN236_RS08545_lanthipeptide

SLSFAVSVLSVSFSACSATVVTRLASCGNCK

96.8%

NC_010816.1and 5 others:

NZ_CP069278.1 Lanthipeptides: JQN89_RS04800_lanthipeptideNZ_JADNCJ010000029.1 Lanthipeptides: I2B64_RS09750_lanthipeptideNZ_JADNLW010000041.1 Lanthipeptides: I2F45_RS10575_lanthipeptideNZ_JADPBO010000046.1 Lanthipeptides: I4V38_RS08850_lanthipeptideNZ_JADPES010000050.1 Lanthipeptides: I4U88_RS09655_lanthipeptide

Lanthipeptides: BLD_RS08345_lanthipeptide

SLSFAVSVLSVSFSACSATVVTRLASCGNCK

SLSFAVSVLSVSFSACS TVVTRLASCGNCK

SLSFAVSVLSVSFSACSVTVVTRLASCGNCK

32.3%

NZ_CP036100.1and 1 other:

NZ_CP072062.1 Lanthipeptides: J5V93_RS29680_lanthipeptide

Lanthipeptides: EXW47_RS29590_lanthipeptide

SVLSVSFSACSATVVTRLASCGNCK

S+L VS + C SC NCK

SILKVSRAVCKTGTCICTTSCSNCK

with 2 more sequence matches

32.3%

NZ_KB976165.1and 1 other:

NZ_MOOT01000054.1 Lanthipeptides: BK765_RS17675_lanthipeptide

Lanthipeptides: ICC_RS37095_lanthipeptide

VSVLSVSFSACSATVVTRLASCGNCK

S+L VS + C + SC NCK

TSILKVSRAPCKSGTCLCTTSCSNCK

17.0%

NZ_CP110813.1:

Lanthipeptides: allorf_3539006_3539200_lanthipeptide

ATVVTRLASCGNC

A TRLA+ GNC

AAWPTRLAAEGNC

allorf_61109_61330

Leader:

MAFLPKSAVDLEFG

Core:

TFGRATKKPCAQAEQYNLAKRPSPALDGLISLNLRWLGEPNFGNALARTSTNGLWFTDD

Core with dehydrations:

DhbFGRADhbKKPCysAQAEQYNLAKRPDhaPALDGLIDhaLNLRWLGEPNFGNALARDhbDhaDhbNGLWFDhbDD

antiSMASH-DB 4.0 matches for allorf_61109_61330

100.0%

NZ_CP046514.1and 9 others:

NZ_CP069278.1 Lanthipeptides: allorf_1033752_1033973_lanthipeptideNZ_GL622638.1 Lanthipeptides: allorf_31875_32096_lanthipeptideNZ_JADMSA010000006.1 Lanthipeptides: allorf_049253_049474_lanthipeptideNZ_JADMUN010000007.1 Lanthipeptides: allorf_076793_077014_lanthipeptideNZ_JADNBL010000011.1 Lanthipeptides: allorf_61109_61330_lanthipeptideNZ_JADPBZ010000019.1 Lanthipeptides: allorf_14831_15052_lanthipeptideNZ_JADPCP010000015.1 Lanthipeptides: allorf_17792_18013_lanthipeptideNZ_JAHTKJ010000004.1 Lanthipeptides: allorf_025782_026003_lanthipeptideNZ_NJNX01000015.1 Lanthipeptides: allorf_53588_53809_lanthipeptide

Lanthipeptides: allorf_1935663_1935884_lanthipeptide

TFGRATKKPCAQAEQYNLAKRPSPALDGLISLNLRWLGEPNFGNALARTSTNGLWFTDD

15.3%

NC_009480.1and 1 other:

NZ_CP047054.1 Lanthipeptides: allorf_2242448_2242588_lanthipeptide

Lanthipeptides: allorf_2226592_2226732_lanthipeptide

ALDGLISLNLRWLGEPNFGNALARTSTNGLW

AL ++ + G P NA++R + G W

ALRTSVARSAELEGRPARRNAVSRATATGYW

15.3%

NZ_PSTW01000024.1:

Lanthipeptides: allorf_20775_20915_lanthipeptide

ALDGLISLNLRWLGEPNFGNALARTSTNGLW

AL ++ + G P NA++R + G W

ALRTSVARSAELEGRPAGRNAVSRATATGYW

with 1 more sequence matches

13.6%

NZ_AP018365.1and 3 others:

NZ_AP018365.1 Lanthipeptides: allorf_8002653_8002877_lanthipeptideNZ_AP018365.1 Lanthipeptides: allorf_8002653_8002877_lanthipeptideNZ_AP018365.1 Lanthipeptides: allorf_8002653_8002877_lanthipeptide

Lanthipeptides: allorf_8002653_8002877_lanthipeptide

RATKKPCAQAEQYNLAKRP

RAT+ PCA RP

RATRAPCATGTDDVSGPRP

MIBiG 4.0 matches for allorf_61109_61330

8.5%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

PALDGLI

PA+ GLI

PAVTGLI

6.8%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

NGLWFT

NG W T

NGGWCT

allorf_62374_62448

Leader:

MGLCGAAHRVHNAAAG

Core:

PGENCDSP

Core with dehydrations:

PGENCysDDhaP

antiSMASH-DB 4.0 matches for allorf_62374_62448

100.0%

NZ_CP046514.1and 9 others:

NZ_CP069278.1 Lanthipeptides: allorf_1035017_1035091_lanthipeptideNZ_GL622638.1 Lanthipeptides: allorf_33140_33214_lanthipeptideNZ_JADMSA010000006.1 Lanthipeptides: allorf_048135_048209_lanthipeptideNZ_JADMUN010000007.1 Lanthipeptides: allorf_078058_078132_lanthipeptideNZ_JADNBL010000011.1 Lanthipeptides: allorf_62374_62448_lanthipeptideNZ_JADPBZ010000019.1 Lanthipeptides: allorf_13714_13788_lanthipeptideNZ_JADPCP010000015.1 Lanthipeptides: allorf_16675_16749_lanthipeptideNZ_JAHTKJ010000004.1 Lanthipeptides: allorf_024665_024739_lanthipeptideNZ_NJNX01000015.1 Lanthipeptides: allorf_54853_54927_lanthipeptide

Lanthipeptides: allorf_1936928_1937002_lanthipeptide

PGENCDSP

allorf_64006_64134

Leader:

MGIVVNRQLNVHGS

Core:

STSALFNIEICSAKKPKNQKASIPNETV

Core with dehydrations:

DhaDhbDhaALFNIEICysDhaAKKPKNQKADhaIPNEDhbV

antiSMASH-DB 4.0 matches for allorf_64006_64134

100.0%

NZ_JADNBL010000011.1and 1 other:

NZ_JADPCP010000015.1 Lanthipeptides: allorf_14989_15117_lanthipeptide

Lanthipeptides: allorf_64006_64134_lanthipeptide

STSALFNIEICSAKKPKNQKASIPNETV

71.4%

NZ_CP046514.1and 6 others:

NZ_CP069278.1 Lanthipeptides: allorf_1036649_1036768_lanthipeptideNZ_GL622638.1 Lanthipeptides: allorf_34772_34891_lanthipeptideNZ_JADMSA010000006.1 Lanthipeptides: allorf_046458_046577_lanthipeptideNZ_JADMUN010000007.1 Lanthipeptides: allorf_079690_079809_lanthipeptideNZ_JADPBZ010000019.1 Lanthipeptides: allorf_12037_12156_lanthipeptideNZ_JAHTKJ010000004.1 Lanthipeptides: allorf_022989_023108_lanthipeptide

Lanthipeptides: allorf_1938560_1938679_lanthipeptide

STSALFNIEICSAKKPKNQKA

STSALFNIEICSAKKPKNQK

STSALFNIEICSAKKPKNQKG

allorf_64040_64156

Leader:

MAAARVPYS

Core:

TSKYVARRSRKTKRLLYRMKRYRSLLVCD

Core with dehydrations:

DhbDhaKYVARRDhaRKDhbKRLLYRMKRYRDhaLLVCysD

antiSMASH-DB 4.0 matches for allorf_64040_64156

100.0%

NZ_JADNBL010000011.1and 2 others:

NZ_JADPCP010000015.1 Lanthipeptides: allorf_14967_15083_lanthipeptideNZ_NJNX01000015.1 Lanthipeptides: allorf_56513_56635_lanthipeptide

Lanthipeptides: allorf_64040_64156_lanthipeptide

TSKYVARRSRKTKRLLYRMKRYRSLLVCD

MIBiG 4.0 matches for allorf_64040_64156

17.2%

BGC0000553.3 (SSGG_RS09925):

Lanthipeptide: SRO15-2212

SLLVCD

SLLVC+

SLLVCE

allorf_79901_80134

Leader:

MSWSGRSICLRLCCIAGDGGAGHHLSCFRNANRASGA

Core:

CLRAIMTLLPRIRIRRIVARIMVRAMASNRSYRRLAQHAR

Core with dehydrations:

CysLRAIMDhbLLPRIRIRRIVARIMVRAMADhaNRDhaYRRLAQHAR

antiSMASH-DB 4.0 matches for allorf_79901_80134

100.0%

NZ_JADMUN010000007.1and 1 other:

NZ_JADNBL010000011.1 Lanthipeptides: allorf_79901_80134_lanthipeptide

Lanthipeptides: allorf_095586_095819_lanthipeptide

CLRAIMTLLPRIRIRRIVARIMVRAMASNRSYRRLAQHAR

allorf_80770_81003

Leader:

MVEHDIGVECAILETKELVCG

Core:

RLAVFISNRRRSPDIKYGCVSMLPLCGDVSGVSNSDMVRPYEHMYGLCRPPKHGCD

Core with dehydrations:

RLAVFIDhaNRRRDhaPDIKYGCysVDhaMLPLCysGDVDhaGVDhaNDhaDMVRPYEHMYGLCysRPPKHGCysD

antiSMASH-DB 4.0 matches for allorf_80770_81003

100.0%

NZ_CP046514.1and 5 others:

NZ_CP069278.1 Lanthipeptides: allorf_1053415_1053648_lanthipeptideNZ_JADMSA010000006.1 Lanthipeptides: allorf_028329_028562_lanthipeptideNZ_JADMUN010000007.1 Lanthipeptides: allorf_096455_096688_lanthipeptideNZ_JADNBL010000011.1 Lanthipeptides: allorf_80770_81003_lanthipeptideNZ_JAHTKJ010000004.1 Lanthipeptides: allorf_006104_006337_lanthipeptide

Lanthipeptides: allorf_1955325_1955558_lanthipeptide

RLAVFISNRRRSPDIKYGCVSMLPLCGDVSGVSNSDMVRPYEHMYGLCRPPKHGCD

23.2%

NZ_LT907978.1:

Lanthipeptides: allorf_2780940_2781146_lanthipeptide

VFISNRRRSPDIKYGCVSMLPLCGDVSGVSNSDMVRPYEHMYGL

VF+ NR + + Y L DVS +S++++VR Y +++ +

VFVRNRNKKSECLY------LLSTDVS-LSDAEIVRIYGNIWQV

17.9%

NZ_GG657757.1and 1 other:

NZ_GG657757.1 Lanthipeptides: allorf_4699229_4699420_lanthipeptide

Lanthipeptides: allorf_4699229_4699420_lanthipeptide

RSPDIKYGCVSMLPLCGDVS

RSP YG + LPL VS

RSPAHTYGNLRWLPLLRQVS

with 3 more sequence matches

14.3%

NZ_CP059991.1:

Lanthipeptides: allorf_7879265_7879423_lanthipeptide

PDIKYGCVSMLPLCGDVS

PD K V + LCG +S

PDSKINSVQICTLCGKLS

12.5%

NZ_KB235904.1:

Lanthipeptides: OSCIL6407_RS32785_lanthipeptide

RRRSPDIKYGCVSMLPLCGDVSGVSNSD

R+R+ + + C++ + L G + G++ D

RKRATSLFHFCLTAIALLGILIGLAFID

10.7%

NZ_CP017599.1and 1 other:

NZ_CP017599.1 Lanthipeptides: BJP34_RS13245_lanthipeptide

Lanthipeptides: BJP34_RS13245_lanthipeptide

PLCGDVSGVSNSDMVRPYEH

P C + GV ++ +V + H

PTCVNTGGVGSTTIVVIFNH

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

Binding sites found:

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 20.60 out of 27.78

Confidence: medium

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 16.73 out of 18.46

Confidence: medium

Additional weak hits (1):

HypR

Description: L-hydroxyproline utilization repressor
Species: Streptomyces coelicolor
Score: 18.94 out of 22.40

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

I2A13_RS07655 - Class II

Cleavage pHMM score: -6.20

RODEO score: 0

Monoisotopic mass: 2913.5 Da

Molecular weight: 2915.4 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2933.4 Da N = 1; 2951.4 Da N = 2; 2969.4 Da N = 3; 2987.4 Da N = 4; 3005.5 Da N = 5; 3023.5 Da N = 6; 3041.5 Da N = 7

allorf_61109_61330 - Class II

Cleavage pHMM score: -4.90

RODEO score: 0

Monoisotopic mass: 6346.3 Da

Molecular weight: 6350.1 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 6368.1 Da N = 1; 6386.1 Da N = 2; 6404.1 Da N = 3; 6422.1 Da N = 4; 6440.2 Da N = 5; 6458.2 Da N = 6; 6476.2 Da N = 7

allorf_62374_62448 - Class II

Cleavage pHMM score: -6.10

RODEO score: 0

Monoisotopic mass: 799.3 Da

Molecular weight: 799.8 Da

Number of bridges: 1

allorf_64006_64134 - Class II

Cleavage pHMM score: -2.10

RODEO score: 0

Monoisotopic mass: 2909.6 Da

Molecular weight: 2911.3 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2929.3 Da N = 1; 2947.3 Da N = 2; 2965.4 Da N = 3; 2983.4 Da N = 4; 3001.4 Da N = 5

allorf_64040_64156 - Class II

Cleavage pHMM score: -6.10

RODEO score: 0

Monoisotopic mass: 3556.1 Da

Molecular weight: 3558.3 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 3576.3 Da N = 1; 3594.3 Da N = 2; 3612.3 Da N = 3; 3630.3 Da N = 4

allorf_79901_80134 - Class II

Cleavage pHMM score: -7.10

RODEO score: 0

Monoisotopic mass: 4733.8 Da

Molecular weight: 4736.8 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 4754.8 Da N = 1; 4772.8 Da N = 2

allorf_80770_81003 - Class II

Cleavage pHMM score: -6.50

RODEO score: 0

Monoisotopic mass: 6173.0 Da

Molecular weight: 6177.1 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 6195.1 Da N = 1; 6213.2 Da N = 2

TFBS definitions

Regulator	Description
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
RpoN	Regulator of nitrogen assimilation and virulence

NZ_JADNBL010000006.1 - Region 1 - terpene-precursor

Download region GenBank file

Download region SVG

Location: 61,797 - 82,879 nt. (total: 21,083 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: acyltransferase kinase

I2A13_RS05450: acyltransferase

smcogs: SMCOG1141: acyltransferase

I2A13_RS05485: PfkB domain protein

smcogs: SMCOG1276: PfkB domain protein

Ligases: synthetase

I2A13_RS05460: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000677.5	0.42	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001911.3	0.38	terpene	raimonol	Streptomyces anulatus
BGC0002309.2	0.36	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0001910.4	0.36	terpene	cyslabdan A, cyslabdan B, cyslabdan C	Streptomyces cyslabdanicus
BGC0001456.3	0.36	terpene	isorenieratene	Streptomyces argillaceus
BGC0000664.5	0.35	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000644.3	0.34	terpene	carotenoid	Dietzia sp. CQ4
BGC0001227.3	0.34	terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000648.3	0.34	terpene	carotenoid	Myxococcus xanthus
BGC0000633.3	0.34	terpene	carotenoid	Streptomyces avermitilis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000677.5	0.42	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001911.3	0.38	terpene	raimonol	Streptomyces anulatus
BGC0002309.2	0.36	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0001910.4	0.36	terpene	cyslabdan A, cyslabdan B, cyslabdan C	Streptomyces cyslabdanicus
BGC0001456.3	0.36	terpene	isorenieratene	Streptomyces argillaceus
BGC0000664.5	0.35	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000644.3	0.34	terpene	carotenoid	Dietzia sp. CQ4
BGC0001227.3	0.34	terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000648.3	0.34	terpene	carotenoid	Myxococcus xanthus
BGC0000633.3	0.34	terpene	carotenoid	Streptomyces avermitilis

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor	FPP	C15	acyclic	PP
diterpene precursor	GGPP	C20	acyclic	PP
sesterterpene precursor	GFPP	C25	acyclic	PP
triterpene precursor	HPP	C30	acyclic	PP

Genes with terpene domains:

I2A13_RS05460: PT_FPPS_like

Domain 1 (48 - 350): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

Transcription Factor Binding Sites

Binding sites found:

NtrC

Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 22.52 out of 29.72

Confidence: medium

Additional weak hits (7):

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.61 out of 30.25

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 19.86 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.94 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 17.10 out of 26.06

Confidence: weak

HipB

Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 21.41 out of 33.73

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 18.19 out of 26.06

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 21.71 out of 29.65

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
NtrC	Nitrogen regulatory protein C