GCF_009866585.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP047419.1 (Rathayibacter sp. VKM Ac-2762)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	terpene-precursor	1,249,025	1,270,125
Region 2	T3PKS	2,401,056	2,442,171
Region 3	lanthipeptide-class-ii	2,711,142	2,740,296
Region 4	oligosaccharide	2,769,125	2,811,045
Region 5	terpene	3,314,635	3,338,842	Low	carotenoid	terpene

NZ_CP047419.1 - Region 1 - terpene-precursor

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Location: 1,249,025 - 1,270,125 nt. (total: 21,101 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: acyltransferase

GTU71_RS05960: acyltransferase

smcogs: SMCOG1141: acyltransferase

Hydrolases: deformylase

GTU71_RS05975: peptide deformylase

smcogs: SMCOG1275: peptide deformylase

Ligases: ligase synthetase

GTU71_RS05940: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

GTU71_RS05970: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000677.5	0.42	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000649.3	0.40	terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001910.4	0.39	terpene	cyslabdan A, cyslabdan B, cyslabdan C	Streptomyces cyslabdanicus
BGC0001456.3	0.39	terpene	isorenieratene	Streptomyces argillaceus
BGC0001483.4	0.38	other (other)	5-isoprenylindole-3-carboxylate β-D-glycosyl ester	Streptomyces sp. RM-5-8
BGC0001911.3	0.38	terpene	raimonol	Streptomyces anulatus
BGC0000664.5	0.38	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000678.5	0.38	terpene	pentalenolactone	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0002348.2	0.37	NRPS	aspulvinone E	Aspergillus terreus NIH2624
BGC0000633.3	0.37	terpene	carotenoid	Streptomyces avermitilis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000677.5	0.42	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000649.3	0.40	terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001910.4	0.39	terpene	cyslabdan A, cyslabdan B, cyslabdan C	Streptomyces cyslabdanicus
BGC0001456.3	0.39	terpene	isorenieratene	Streptomyces argillaceus
BGC0001483.4	0.38	other (other)	5-isoprenylindole-3-carboxylate β-D-glycosyl ester	Streptomyces sp. RM-5-8
BGC0001911.3	0.38	terpene	raimonol	Streptomyces anulatus
BGC0000664.5	0.38	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000678.5	0.38	terpene	pentalenolactone	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0002348.2	0.37	NRPS	aspulvinone E	Aspergillus terreus NIH2624
BGC0000633.3	0.37	terpene	carotenoid	Streptomyces avermitilis

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor	FPP	C15	acyclic	PP
diterpene precursor	GGPP	C20	acyclic	PP
sesterterpene precursor	GFPP	C25	acyclic	PP
triterpene precursor	HPP	C30	acyclic	PP

Genes with terpene domains:

GTU71_RS05940: PT_FPPS_like

Domain 1 (45 - 365): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (4):

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 22.68 out of 30.22

Confidence: weak

RutR

Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.66 out of 26.85

Confidence: weak

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 22.68 out of 30.22

Confidence: weak

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 19.28 out of 28.19

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description

NZ_CP047419.1 - Region 2 - T3PKS

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Location: 2,401,056 - 2,442,171 nt. (total: 41,116 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

GTU71_RS11385: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

GTU71_RS11495: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Hydrolases: esterase

GTU71_RS11355: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase

smcogs: SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase

Lyases: dehydratase

GTU71_RS11370: NAD-dependent epimerase/dehydratase

smcogs: SMCOG1010: NAD-dependent epimerase/dehydratase

Ligases: synthase

GTU71_RS11390: chalcone and stilbene synthase domain protein

smcogs: SMCOG1024: chalcone and stilbene synthase domain protein

Translocases: permease

GTU71_RS11440: phenylalanine-specific permease

smcogs: SMCOG1038: phenylalanine-specific permease

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000282.3	0.53	PKS	2-methoxy-5-methyl-6-(13-methyltetradecyl)-1,4-benzoquinone, 2-methoxy-5-methyl-6-(13-methyltetradecyl)phenol	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001962.3	0.52	PKS	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0001928.2	0.48	other (other)	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0001974.2	0.46	other (other)	kainic acid, Kainic acid lactone	Digenea simplex
BGC0002332.2	0.46	PKS	4-hydroxy-6-pentadecylpyran-2-one, 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one, Adipostatin A	Candidatus Entotheonella sp.
BGC0002404.2	0.45	other (other)	falcarindiol	Solanum lycopersicum
BGC0001831.3	0.45	PKS	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001987.2	0.43	PKS	koreenceine A, koreenceine B, koreenceine C, koreenceine D	Pseudomonas koreensis
BGC0000671.3	0.43	terpene	momilactone B	Oryza sativa Japonica Group
BGC0002362.3	0.43	PKS	loseolamycin A1, loseolamycin A2	Micromonospora endolithica

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000282.3	0.53	PKS	2-methoxy-5-methyl-6-(13-methyltetradecyl)-1,4-benzoquinone, 2-methoxy-5-methyl-6-(13-methyltetradecyl)phenol	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001962.3	0.52	PKS	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0001928.2	0.48	other (other)	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0001974.2	0.46	other (other)	kainic acid, Kainic acid lactone	Digenea simplex
BGC0002332.2	0.46	PKS	4-hydroxy-6-pentadecylpyran-2-one, 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one, Adipostatin A	Candidatus Entotheonella sp.
BGC0002404.2	0.45	other (other)	falcarindiol	Solanum lycopersicum
BGC0001831.3	0.45	PKS	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001987.2	0.43	PKS	koreenceine A, koreenceine B, koreenceine C, koreenceine D	Pseudomonas koreensis
BGC0000671.3	0.43	terpene	momilactone B	Oryza sativa Japonica Group
BGC0002362.3	0.43	PKS	loseolamycin A1, loseolamycin A2	Micromonospora endolithica

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

NtrC

Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 21.87 out of 29.72

Confidence: medium

Additional weak hits (9):

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 15.56 out of 21.84

Confidence: weak

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 20.00 out of 31.73

Confidence: weak

HgtR

Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 18.82 out of 36.54

Confidence: weak

HgtR

Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 20.77 out of 36.54

Confidence: weak

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 14.41 out of 21.55

Confidence: weak

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 21.27 out of 30.22

Confidence: weak

CRP

Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 15.93 out of 19.26

Confidence: weak

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 17.67 out of 24.78

Confidence: weak

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 19.52 out of 28.19

Confidence: weak

Detailed domain annotation

Selected features only

Show module domains

TFBS Finder

TFBS definitions

Regulator	Description
NtrC	Nitrogen regulatory protein C

NZ_CP047419.1 - Region 3 - lanthipeptide-class-ii

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Location: 2,711,142 - 2,740,296 nt. (total: 29,155 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: oxidoreductase

GTU71_RS12800: oxidoreductase

smcogs: SMCOG1083: oxidoreductase

Transferases: methyltransferase

GTU71_RS12835: methyltransferase

smcogs: SMCOG1248: methyltransferase

Lyases: cyclase

GTU71_RS12790: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

GTU71_RS12810: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001229.4	0.65	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000520.5	0.59	ribosomal	lacticin 3147 A1, lacticin 3147 A2	Lactococcus lactis
BGC0000555.3	0.56	ribosomal	staphylococcin C55 α, staphylococcin C55 β	Staphylococcus aureus
BGC0002110.3	0.54	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0000623.3	0.53	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0001311.5	0.53	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0000525.5	0.53	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0002663.2	0.53	ribosomal	amyloliquecidin GF610	Bacillus amyloliquefaciens UMAF6639
BGC0001555.4	0.52	ribosomal	colicin V	Escherichia coli chi7122
BGC0000517.4	0.51	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001229.4	0.65	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000520.5	0.59	ribosomal	lacticin 3147 A1, lacticin 3147 A2	Lactococcus lactis
BGC0000555.3	0.56	ribosomal	staphylococcin C55 α, staphylococcin C55 β	Staphylococcus aureus
BGC0002110.3	0.54	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0000623.3	0.53	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0001311.5	0.53	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0000525.5	0.53	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0002663.2	0.53	ribosomal	amyloliquecidin GF610	Bacillus amyloliquefaciens UMAF6639
BGC0001555.4	0.52	ribosomal	colicin V	Escherichia coli chi7122
BGC0000517.4	0.51	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for GTU71_RS12790

GTU71_RS12785

Leader:

MKMTNNADDVLRRTGFVDESHLSDLVAGDRAAGEQEVGAGS

Core:

PVIISAVSGTVASATAVSALVTSSGLCPTFSCTGEC

Core with dehydrations:

PVIIDhaAVDhaGDhbVADhaADhbAVDhaALVDhbDhaDhaGLCysPDhbFDhaCysDhbGECys

antiSMASH-DB 4.0 matches for GTU71_RS12785

100.0%

NZ_CP047419.1and 3 others:

NZ_CP047419.1 Lanthipeptides: GTU71_RS12785_lanthipeptideNZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15570_lanthipeptideNZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15570_lanthipeptide

Lanthipeptides: GTU71_RS12785_lanthipeptide

PVIISAVSGTVASATAVSALVTSSGLCPTFSCTGEC

52.8%

NZ_CP086141.1and 1 other:

NZ_CP086141.1 Lanthipeptides: LL065_RS24780_lanthipeptide

Lanthipeptides: LL065_RS24780_lanthipeptide

ISAVSGTVASATAVSALVTSSGLCPTFSC

+SA+S TVASATAVSAL T + C T SC

VSAISATVASATAVSALFTVTSAC-TKSC

52.8%

NZ_CP086141.1and 1 other:

NZ_CP086141.1 Lanthipeptides: LL065_RS24780_lanthipeptide

Lanthipeptides: LL065_RS24780_lanthipeptide

IISAVSGTVASATAVSALVTSSGLCPTFSC

++SA+S TVASATAVSAL T + C T SC

VVSAISATVASATAVSALFTVTSAC-TKSC

with 78 more sequence matches

Only the first 10 are displayed here.

47.2%

NZ_BQXZ01000001.1and 1 other:

NZ_BQXZ01000001.1 Lanthipeptides: OCU69_RS05005_lanthipeptide

Lanthipeptides: OCU69_RS05005_lanthipeptide

IISAVSGTVASATAVSALVTSSGLCPT

I+SA+S TVASATA+SAL T + C T

IVSAISATVASATAISALFTVTSACTT

44.4%

NC_017299.1and 1 other:

NC_017299.1 Lanthipeptides: H04402_RS03100_lanthipeptide

Lanthipeptides: H04402_RS03100_lanthipeptide

VSGTVASATAVSALVTSSGLCPT

VS TVASATAVSAL T + C T

VSATVASATAVSALFTVTSACTT

41.7%

NZ_FQZK01000006.1and 2 others:

NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13105_lanthipeptideNZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13105_lanthipeptide

Lanthipeptides: BUE45_RS13105_lanthipeptide

VSGTVASATAVSALVTSSGLCPTFSCTGEC

+S TVAS TA+SA CPT CT C

ISATVASVTAISAAWGDG--CPTTVCTSRC

38.9%

NZ_MIFN01000022.1and 1 other:

NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide

Lanthipeptides: BHL26_RS15355_lanthipeptide

IISAVSGTVASATAVSALVTSSGLCPTFSCTGEC

I V T + TAVS + SS CP+ +CT C

ITPTVLATTGALTAVSGYI-SSNTCPSTACTRAC

37.8%

NZ_CM000756.1and 17 others:

NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptideNZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14765_lanthipeptideNZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide

Lanthipeptides: BTHUR0011_RS14765_lanthipeptide

GTVASATAVSAL--VTSSGLCPTFSCTGEC

GT A TA+SA+ VT+ CPT +C+ C

GTPAIVTAISAVTAVTAQSPCPTSACSKSC

36.8%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

GTVASATAVSALVT-SSGLCPTFSCTGEC

T +S T ++A VT S+ LCPT CT C

ATTSSWTCITAGVTVSASLCPTTKCTSRC

36.1%

NZ_CP013862.1and 1 other:

NZ_CP013862.1 Lanthipeptides: AOX59_RS09365_lanthipeptide

Lanthipeptides: AOX59_RS09365_lanthipeptide

TVASATAVSALVTSSGLCPTFSCTGEC

+VA AVSAL CPT CT +C

SVACGIAVSAL-----FCPTTKCTSQC

36.1%

NZ_CP036019.1and 7 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27190_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide

Lanthipeptides: EXW52_RS27190_lanthipeptide

VSGTVASATAVSALVTSSGLCPTFSCTGEC

VS AT + S GLCPT CT +C

VSPETTPATPTIVVAISVGLCPTNRCTSKC

36.1%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

VSGTVASATAVSALVTSSGLCPTFSCTGEC

VS AT + S GLCPT CT +C

VSPETTPATPTIVVAISVGLCPTTKCTSKC

36.1%

NZ_CP047645.1and 5 others:

NZ_CP047645.1 Lanthipeptides: GSN02_RS17435_lanthipeptideNZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptideNZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptideNZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptideNZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide

Lanthipeptides: GSN02_RS17435_lanthipeptide

IISAVSGTVASATAVSALVTSSGLCPTFSCTGEC

II+A++GT + T S+ CPT +CT C

IITALTGTTFTVTL------SAASCPTSACTNLC

MIBiG 4.0 matches for GTU71_RS12785

35.1%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

AVSGTVASATAVSALV---TSSGLCPTFSCTGEC

AV+G + A+ A V S+ CPT CT C

AVTGLILGIVAIQAGVAVGVSAAFCPTTKCTSRC

16.7%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

LCPTFSCTGEC

CPT CT +C

FCPTTKCTSKC

GTU71_RS12805

Leader:

MSQYDVALFEEIAEQDFDSVAYGA

Core:

CTTNTFTLSNVLGNQGGWCTLTVECQPNCK

Core with dehydrations:

CysDhbDhbNDhbFDhbLDhaNVLGNQGGWCysDhbLDhbVECysQPNCysK

antiSMASH-DB 4.0 matches for GTU71_RS12805

100.0%

NZ_CP047419.1and 3 others:

NZ_CP047419.1 Lanthipeptides: GTU71_RS12805_lanthipeptideNZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptideNZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptide

Lanthipeptides: GTU71_RS12805_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNCK

86.7%

NZ_BMMP01000005.1and 3 others:

NZ_BMMP01000005.1 Lanthipeptides: IEY56_RS28370_lanthipeptideNZ_FMHJ01000003.1 Lanthipeptides: H181DRAFT_RS07545_lanthipeptideNZ_FMHJ01000003.1 Lanthipeptides: H181DRAFT_RS07545_lanthipeptide

Lanthipeptides: IEY56_RS28370_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNCK

CTTNTF+LS+VLGN GGWCTLTVECQPNC

CTTNTFSLSDVLGNTGGWCTLTVECQPNCN

83.3%

NZ_CP107567.1and 3 others:

NZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptideNZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptideNZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptide

Lanthipeptides: OGH68_RS19760_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LS+ LGNQGGWCTLT ECQPNC

CTTNTFSLSDWLGNQGGWCTLTKECQPNC

with 103 more sequence matches

Only the first 10 are displayed here.

83.3%

NZ_QLLX01000002.1and 1 other:

NZ_QLLX01000002.1 Lanthipeptides: K378_RS05175_lanthipeptide

Lanthipeptides: K378_RS05175_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LS+ L NQGGWCTLTVECQPNC

CTTNTFSLSDALTNQGGWCTLTVECQPNC

80.0%

NZ_AKXV01000031.1and 4 others:

NZ_AKXV01000031.1 Lanthipeptides: Y19_RS0109895_lanthipeptideNZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13545_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide

Lanthipeptides: Y19_RS0109895_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

C+TNTF+LS+ LGNQGGWCTLT ECQPNC

CSTNTFSLSDFLGNQGGWCTLTKECQPNC

80.0%

NZ_BNBV01000031.1and 1 other:

NZ_BNBV01000031.1 Lanthipeptides: IE286_RS22995_lanthipeptide

Lanthipeptides: IE286_RS22995_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LS+ LGN GGWCTLT ECQPNC

CTTNTFSLSDALGNSGGWCTLTKECQPNC

80.0%

NZ_CP016795.1and 5 others:

NZ_CP016795.1 Lanthipeptides: BC342_RS18360_lanthipeptideNZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptideNZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptideNZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptideNZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide

Lanthipeptides: BC342_RS18360_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNCK

CTTNTF+LS+ LGN GGWCTLT ECQPNC

CTTNTFSLSDALGNHGGWCTLTKECQPNCS

80.0%

NZ_CP043317.1and 1 other:

NZ_CP043317.1 Lanthipeptides: FYC74_RS17680_lanthipeptide

Lanthipeptides: FYC74_RS17680_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNCK

CTTNTF+LS+ LGN GGWCTLT ECQPNC

CTTNTFSLSDSLGNHGGWCTLTKECQPNCS

80.0%

NZ_CP084530.1and 1 other:

NZ_CP084530.1 Lanthipeptides: LDO05_RS02075_lanthipeptide

Lanthipeptides: LDO05_RS02075_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTFTLSN LGN GGWCTLT ECQ +C

CTTNTFTLSNYLGNNGGWCTLTKECQRSC

80.0%

NZ_JAASAG010000001.1and 1 other:

NZ_JAASAG010000001.1 Lanthipeptides: HCC61_RS30395_lanthipeptide

Lanthipeptides: HCC61_RS30395_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LS+ L N GGWCTLTVECQPNC

CTTNTFSLSDALTNTGGWCTLTVECQPNC

76.7%

NZ_BJTV01000004.1and 1 other:

NZ_BJTV01000004.1 Lanthipeptides: TNCT1_RS10200_lanthipeptide

Lanthipeptides: TNCT1_RS10200_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LS+ LGN GGWCTLT ECQ NC

CTTNTFSLSDALGNHGGWCTLTKECQANC

76.7%

NZ_BNCA01000011.1and 1 other:

NZ_BNCA01000011.1 Lanthipeptides: IE314_RS15865_lanthipeptide

Lanthipeptides: IE314_RS15865_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LS+ +GN GGWCTLT ECQPNC

CTTNTFSLSDAVGNHGGWCTLTKECQPNC

76.7%

NZ_LT985747.1and 1 other:

NZ_LT985747.1 Lanthipeptides: C8268_RS00165_lanthipeptide

Lanthipeptides: C8268_RS00165_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTFTLS+ LGN+GGWCTLT ECQ +C

CTTNTFTLSDYLGNKGGWCTLTKECQRSC

MIBiG 4.0 matches for GTU71_RS12805

83.3%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LSN LGN GGWCTLT ECQPNC

CTTNTFSLSNALGNNGGWCTLTKECQPNC

46.7%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

FTLSNVLGNQGGWCTLTVECQPNC

+ +S LGN+G +CTLTVEC P+C

YNISCRLGNKGAYCTLTVECMPSC

23.1%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTLTVECQPNC

CTL+ ECQPNC

CTLSKECQPNC

with 1 more sequence matches

11.8%

BGC0000535.4 (ADJ56352.1):

Lanthipeptide: nisin A

CQPNCK

C P CK

CTPGCK

allorf_2720111_2720311

Leader:

MTSPGA

Core:

RNCLPAESRVHPLGQPPIPLSGLLLPLRPFLGSIVQSSSGLHRSRSTSGDLLVGWTGGCP

Core with dehydrations:

RNCysLPAEDhaRVHPLGQPPIPLDhaGLLLPLRPFLGDhaIVQDhaDhaDhaGLHRDhaRDhaDhbDhaGDLLVGWDhbGGCysP

antiSMASH-DB 4.0 matches for allorf_2720111_2720311

100.0%

NZ_CP047419.1and 3 others:

NZ_CP047419.1 Lanthipeptides: allorf_2720111_2720311_lanthipeptideNZ_PSTO01000045.1 Lanthipeptides: allorf_08713_08913_lanthipeptideNZ_PSTO01000045.1 Lanthipeptides: allorf_08713_08913_lanthipeptide

Lanthipeptides: allorf_2720111_2720311_lanthipeptide

RNCLPAESRVHPLGQPPIPLSGLLLPLRPFLGSIVQSSSGLHRSRSTSGDLLVGWTGGCP

16.7%

NZ_CP094446.1:

Lanthipeptides: L3476_RS23825_lanthipeptide

SRVHPLGQPPIPLSGLLLPLRPFLGSIVQSSSGL

S V P G P +S + +P + +I + SG+

SDVEPRGTPATIVSAVTRSSKPCISAIGSAISGI

13.3%

NZ_CP031447.1:

Lanthipeptides: allorf_0156643_0156801_lanthipeptide

PAESRVHPLGQPPI

PAE R H L PP+

PAEVRAHLLDSPPV

with 1 more sequence matches

11.7%

NZ_MKZR01000001.1:

Lanthipeptides: allorf_2981606_2981719_lanthipeptide

RNCLPAESRVHPLGQPPIP

R+ +P + PL +PP+P

RSAIPVYYLLRPLNRPPMP

Lanthipeptide(s) for GTU71_RS12810

GTU71_RS12785

Leader:

MKMTNNADDVLRRTGFVDESHLSDLVAGDRAAGEQEVGAGS

Core:

PVIISAVSGTVASATAVSALVTSSGLCPTFSCTGEC

Core with dehydrations:

PVIIDhaAVDhaGDhbVADhaADhbAVDhaALVDhbDhaDhaGLCysPDhbFDhaCysDhbGECys

antiSMASH-DB 4.0 matches for GTU71_RS12785

100.0%

NZ_CP047419.1and 3 others:

NZ_CP047419.1 Lanthipeptides: GTU71_RS12785_lanthipeptideNZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15570_lanthipeptideNZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15570_lanthipeptide

Lanthipeptides: GTU71_RS12785_lanthipeptide

PVIISAVSGTVASATAVSALVTSSGLCPTFSCTGEC

52.8%

NZ_CP086141.1and 1 other:

NZ_CP086141.1 Lanthipeptides: LL065_RS24780_lanthipeptide

Lanthipeptides: LL065_RS24780_lanthipeptide

ISAVSGTVASATAVSALVTSSGLCPTFSC

+SA+S TVASATAVSAL T + C T SC

VSAISATVASATAVSALFTVTSAC-TKSC

52.8%

NZ_CP086141.1and 1 other:

NZ_CP086141.1 Lanthipeptides: LL065_RS24780_lanthipeptide

Lanthipeptides: LL065_RS24780_lanthipeptide

IISAVSGTVASATAVSALVTSSGLCPTFSC

++SA+S TVASATAVSAL T + C T SC

VVSAISATVASATAVSALFTVTSAC-TKSC

with 78 more sequence matches

Only the first 10 are displayed here.

47.2%

NZ_BQXZ01000001.1and 1 other:

NZ_BQXZ01000001.1 Lanthipeptides: OCU69_RS05005_lanthipeptide

Lanthipeptides: OCU69_RS05005_lanthipeptide

IISAVSGTVASATAVSALVTSSGLCPT

I+SA+S TVASATA+SAL T + C T

IVSAISATVASATAISALFTVTSACTT

44.4%

NC_017299.1and 1 other:

NC_017299.1 Lanthipeptides: H04402_RS03100_lanthipeptide

Lanthipeptides: H04402_RS03100_lanthipeptide

VSGTVASATAVSALVTSSGLCPT

VS TVASATAVSAL T + C T

VSATVASATAVSALFTVTSACTT

41.7%

NZ_FQZK01000006.1and 2 others:

NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13105_lanthipeptideNZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13105_lanthipeptide

Lanthipeptides: BUE45_RS13105_lanthipeptide

VSGTVASATAVSALVTSSGLCPTFSCTGEC

+S TVAS TA+SA CPT CT C

ISATVASVTAISAAWGDG--CPTTVCTSRC

38.9%

NZ_MIFN01000022.1and 1 other:

NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide

Lanthipeptides: BHL26_RS15355_lanthipeptide

IISAVSGTVASATAVSALVTSSGLCPTFSCTGEC

I V T + TAVS + SS CP+ +CT C

ITPTVLATTGALTAVSGYI-SSNTCPSTACTRAC

37.8%

NZ_CM000756.1and 17 others:

Lanthipeptides: BTHUR0011_RS14765_lanthipeptide

GTVASATAVSAL--VTSSGLCPTFSCTGEC

GT A TA+SA+ VT+ CPT +C+ C

GTPAIVTAISAVTAVTAQSPCPTSACSKSC

36.8%

NC_006322.1and 7 others:

Lanthipeptides: BLI_RS20290_lanthipeptide

GTVASATAVSALVT-SSGLCPTFSCTGEC

T +S T ++A VT S+ LCPT CT C

ATTSSWTCITAGVTVSASLCPTTKCTSRC

36.1%

NZ_CP013862.1and 1 other:

NZ_CP013862.1 Lanthipeptides: AOX59_RS09365_lanthipeptide

Lanthipeptides: AOX59_RS09365_lanthipeptide

TVASATAVSALVTSSGLCPTFSCTGEC

+VA AVSAL CPT CT +C

SVACGIAVSAL-----FCPTTKCTSQC

36.1%

NZ_CP036019.1and 7 others:

Lanthipeptides: EXW52_RS27190_lanthipeptide

VSGTVASATAVSALVTSSGLCPTFSCTGEC

VS AT + S GLCPT CT +C

VSPETTPATPTIVVAISVGLCPTNRCTSKC

36.1%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

VSGTVASATAVSALVTSSGLCPTFSCTGEC

VS AT + S GLCPT CT +C

VSPETTPATPTIVVAISVGLCPTTKCTSKC

36.1%

NZ_CP047645.1and 5 others:

Lanthipeptides: GSN02_RS17435_lanthipeptide

IISAVSGTVASATAVSALVTSSGLCPTFSCTGEC

II+A++GT + T S+ CPT +CT C

IITALTGTTFTVTL------SAASCPTSACTNLC

MIBiG 4.0 matches for GTU71_RS12785

35.1%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

AVSGTVASATAVSALV---TSSGLCPTFSCTGEC

AV+G + A+ A V S+ CPT CT C

AVTGLILGIVAIQAGVAVGVSAAFCPTTKCTSRC

16.7%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

LCPTFSCTGEC

CPT CT +C

FCPTTKCTSKC

GTU71_RS12805

Leader:

MSQYDVALFEEIAEQDFDSVAYGA

Core:

CTTNTFTLSNVLGNQGGWCTLTVECQPNCK

Core with dehydrations:

CysDhbDhbNDhbFDhbLDhaNVLGNQGGWCysDhbLDhbVECysQPNCysK

antiSMASH-DB 4.0 matches for GTU71_RS12805

100.0%

NZ_CP047419.1and 3 others:

NZ_CP047419.1 Lanthipeptides: GTU71_RS12805_lanthipeptideNZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptideNZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptide

Lanthipeptides: GTU71_RS12805_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNCK

86.7%

NZ_BMMP01000005.1and 3 others:

NZ_BMMP01000005.1 Lanthipeptides: IEY56_RS28370_lanthipeptideNZ_FMHJ01000003.1 Lanthipeptides: H181DRAFT_RS07545_lanthipeptideNZ_FMHJ01000003.1 Lanthipeptides: H181DRAFT_RS07545_lanthipeptide

Lanthipeptides: IEY56_RS28370_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNCK

CTTNTF+LS+VLGN GGWCTLTVECQPNC

CTTNTFSLSDVLGNTGGWCTLTVECQPNCN

83.3%

NZ_CP107567.1and 3 others:

NZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptideNZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptideNZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptide

Lanthipeptides: OGH68_RS19760_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LS+ LGNQGGWCTLT ECQPNC

CTTNTFSLSDWLGNQGGWCTLTKECQPNC

with 103 more sequence matches

Only the first 10 are displayed here.

83.3%

NZ_QLLX01000002.1and 1 other:

NZ_QLLX01000002.1 Lanthipeptides: K378_RS05175_lanthipeptide

Lanthipeptides: K378_RS05175_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LS+ L NQGGWCTLTVECQPNC

CTTNTFSLSDALTNQGGWCTLTVECQPNC

80.0%

NZ_AKXV01000031.1and 4 others:

Lanthipeptides: Y19_RS0109895_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

C+TNTF+LS+ LGNQGGWCTLT ECQPNC

CSTNTFSLSDFLGNQGGWCTLTKECQPNC

80.0%

NZ_BNBV01000031.1and 1 other:

NZ_BNBV01000031.1 Lanthipeptides: IE286_RS22995_lanthipeptide

Lanthipeptides: IE286_RS22995_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LS+ LGN GGWCTLT ECQPNC

CTTNTFSLSDALGNSGGWCTLTKECQPNC

80.0%

NZ_CP016795.1and 5 others:

Lanthipeptides: BC342_RS18360_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNCK

CTTNTF+LS+ LGN GGWCTLT ECQPNC

CTTNTFSLSDALGNHGGWCTLTKECQPNCS

80.0%

NZ_CP043317.1and 1 other:

NZ_CP043317.1 Lanthipeptides: FYC74_RS17680_lanthipeptide

Lanthipeptides: FYC74_RS17680_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNCK

CTTNTF+LS+ LGN GGWCTLT ECQPNC

CTTNTFSLSDSLGNHGGWCTLTKECQPNCS

80.0%

NZ_CP084530.1and 1 other:

NZ_CP084530.1 Lanthipeptides: LDO05_RS02075_lanthipeptide

Lanthipeptides: LDO05_RS02075_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTFTLSN LGN GGWCTLT ECQ +C

CTTNTFTLSNYLGNNGGWCTLTKECQRSC

80.0%

NZ_JAASAG010000001.1and 1 other:

NZ_JAASAG010000001.1 Lanthipeptides: HCC61_RS30395_lanthipeptide

Lanthipeptides: HCC61_RS30395_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LS+ L N GGWCTLTVECQPNC

CTTNTFSLSDALTNTGGWCTLTVECQPNC

76.7%

NZ_BJTV01000004.1and 1 other:

NZ_BJTV01000004.1 Lanthipeptides: TNCT1_RS10200_lanthipeptide

Lanthipeptides: TNCT1_RS10200_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LS+ LGN GGWCTLT ECQ NC

CTTNTFSLSDALGNHGGWCTLTKECQANC

76.7%

NZ_BNCA01000011.1and 1 other:

NZ_BNCA01000011.1 Lanthipeptides: IE314_RS15865_lanthipeptide

Lanthipeptides: IE314_RS15865_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LS+ +GN GGWCTLT ECQPNC

CTTNTFSLSDAVGNHGGWCTLTKECQPNC

76.7%

NZ_LT985747.1and 1 other:

NZ_LT985747.1 Lanthipeptides: C8268_RS00165_lanthipeptide

Lanthipeptides: C8268_RS00165_lanthipeptide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTFTLS+ LGN+GGWCTLT ECQ +C

CTTNTFTLSDYLGNKGGWCTLTKECQRSC

MIBiG 4.0 matches for GTU71_RS12805

83.3%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

CTTNTFTLSNVLGNQGGWCTLTVECQPNC

CTTNTF+LSN LGN GGWCTLT ECQPNC

CTTNTFSLSNALGNNGGWCTLTKECQPNC

46.7%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

FTLSNVLGNQGGWCTLTVECQPNC

+ +S LGN+G +CTLTVEC P+C

YNISCRLGNKGAYCTLTVECMPSC

23.1%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTLTVECQPNC

CTL+ ECQPNC

CTLSKECQPNC

with 1 more sequence matches

11.8%

BGC0000535.4 (ADJ56352.1):

Lanthipeptide: nisin A

CQPNCK

C P CK

CTPGCK

allorf_2720111_2720311

Leader:

MTSPGA

Core:

RNCLPAESRVHPLGQPPIPLSGLLLPLRPFLGSIVQSSSGLHRSRSTSGDLLVGWTGGCP

Core with dehydrations:

RNCysLPAEDhaRVHPLGQPPIPLDhaGLLLPLRPFLGDhaIVQDhaDhaDhaGLHRDhaRDhaDhbDhaGDLLVGWDhbGGCysP

antiSMASH-DB 4.0 matches for allorf_2720111_2720311

100.0%

NZ_CP047419.1and 3 others:

NZ_CP047419.1 Lanthipeptides: allorf_2720111_2720311_lanthipeptideNZ_PSTO01000045.1 Lanthipeptides: allorf_08713_08913_lanthipeptideNZ_PSTO01000045.1 Lanthipeptides: allorf_08713_08913_lanthipeptide

Lanthipeptides: allorf_2720111_2720311_lanthipeptide

RNCLPAESRVHPLGQPPIPLSGLLLPLRPFLGSIVQSSSGLHRSRSTSGDLLVGWTGGCP

16.7%

NZ_CP094446.1:

Lanthipeptides: L3476_RS23825_lanthipeptide

SRVHPLGQPPIPLSGLLLPLRPFLGSIVQSSSGL

S V P G P +S + +P + +I + SG+

SDVEPRGTPATIVSAVTRSSKPCISAIGSAISGI

13.3%

NZ_CP031447.1:

Lanthipeptides: allorf_0156643_0156801_lanthipeptide

PAESRVHPLGQPPI

PAE R H L PP+

PAEVRAHLLDSPPV

with 1 more sequence matches

11.7%

NZ_MKZR01000001.1:

Lanthipeptides: allorf_2981606_2981719_lanthipeptide

RNCLPAESRVHPLGQPPIP

R+ +P + PL +PP+P

RSAIPVYYLLRPLNRPPMP

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

Binding sites found:

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.35 out of 23.79

Confidence: medium

Additional weak hits (9):

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 19.32 out of 26.33

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 15.81 out of 29.38

Confidence: weak

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 19.70 out of 26.33

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 20.00 out of 29.65

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 16.68 out of 29.25

Confidence: weak

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 17.57 out of 28.19

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 20.49 out of 29.65

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 19.75 out of 29.65

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 19.75 out of 29.65

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

GTU71_RS12785 - Class II

Cleavage pHMM score: -3.20

RODEO score: 0

Monoisotopic mass: 3169.6 Da

Molecular weight: 3171.6 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3189.6 Da N = 1; 3207.7 Da N = 2; 3225.7 Da N = 3; 3243.7 Da N = 4; 3261.7 Da N = 5; 3279.7 Da N = 6; 3297.8 Da N = 7; 3315.8 Da N = 8; 3333.8 Da N = 9

GTU71_RS12805 - Class II

Cleavage pHMM score: -3.60

RODEO score: 0

Monoisotopic mass: 3105.4 Da

Molecular weight: 3107.5 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3125.5 Da N = 1; 3143.5 Da N = 2; 3161.6 Da N = 3

allorf_2720111_2720311 - Class II

Cleavage pHMM score: -6.80

RODEO score: 0

Monoisotopic mass: 6084.3 Da

Molecular weight: 6088.0 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 6106.0 Da N = 1; 6124.0 Da N = 2; 6142.0 Da N = 3; 6160.1 Da N = 4; 6178.1 Da N = 5; 6196.1 Da N = 6; 6214.1 Da N = 7; 6232.1 Da N = 8; 6250.2 Da N = 9

GTU71_RS12785 - Class II

Cleavage pHMM score: -3.20

RODEO score: 0

Monoisotopic mass: 3169.6 Da

Molecular weight: 3171.6 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3189.6 Da N = 1; 3207.7 Da N = 2; 3225.7 Da N = 3; 3243.7 Da N = 4; 3261.7 Da N = 5; 3279.7 Da N = 6; 3297.8 Da N = 7; 3315.8 Da N = 8; 3333.8 Da N = 9

GTU71_RS12805 - Class II

Cleavage pHMM score: -3.60

RODEO score: 0

Monoisotopic mass: 3105.4 Da

Molecular weight: 3107.5 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3125.5 Da N = 1; 3143.5 Da N = 2; 3161.6 Da N = 3

allorf_2720111_2720311 - Class II

Cleavage pHMM score: -6.80

RODEO score: 0

Monoisotopic mass: 6084.3 Da

Molecular weight: 6088.0 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 6106.0 Da N = 1; 6124.0 Da N = 2; 6142.0 Da N = 3; 6160.1 Da N = 4; 6178.1 Da N = 5; 6196.1 Da N = 6; 6214.1 Da N = 7; 6232.1 Da N = 8; 6250.2 Da N = 9

TFBS definitions

Regulator	Description
IolR	Regulator of the inositol catabolism

NZ_CP047419.1 - Region 4 - oligosaccharide

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Location: 2,769,125 - 2,811,045 nt. (total: 41,921 nt) Show pHMM detection rules used

oligosaccharide: (repeatable(3, [DUF1205, Glyco_transf_28, Glycos_transf_1, Glycos_transf_2, MGT]) and minscore(MGT, 150))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase oxidase

GTU71_RS13075: FAD linked oxidase domain protein

smcogs: SMCOG1138: FAD linked oxidase domain protein

GTU71_RS13095: acyl-CoA dehydrogenase type 2

smcogs: SMCOG1191: acyl-CoA dehydrogenase type 2

Transferases: glycosyltransferase

GTU71_RS13050: glycosyltransferase

smcogs: SMCOG1102: glycosyltransferase

GTU71_RS13080: glycosyltransferase, MGT family

smcogs: SMCOG1062: glycosyltransferase, MGT family

Hydrolases: hydrolase

GTU71_RS13040: metallo-beta-lactamase family protein

smcogs: SMCOG1170: metallo-beta-lactamase family protein

Translocases: transporter

GTU71_RS13020: sugar-binding lipoprotein

smcogs: SMCOG1143: sugar-binding lipoprotein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000277.5	0.46	PKS	urdamycin	Streptomyces fradiae
BGC0001387.5	0.42	other (other)	nucleocidin	Streptomyces calvus
BGC0000495.5	0.41	ribosomal	actagardine	Actinoplanes garbadinensis
BGC0000662.5	0.40	terpene	grixazone A	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001364.3	0.40	ribosomal	cinnamycin B	Actinomadura atramentaria DSM 43919
BGC0000889.5	0.40	other (other)	bagremycin A, bagremycin B	Streptomyces sp. WK-5344
BGC0001294.5	0.40	other (other)	7-prenylisatin	Streptomyces sp. MBT28
BGC0000885.3	0.40	other (other)	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0002621.2	0.40	other (other)	angustmycin A, angustmycin B, angustmycin C, aristeromycin, arabinofuranosyladenine	Streptomyces angustmyceticus
BGC0001592.5	0.40	other (other)	ferroverdin, bagremycin	Streptomyces lunaelactis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000277.5	0.46	PKS	urdamycin	Streptomyces fradiae
BGC0001387.5	0.42	other (other)	nucleocidin	Streptomyces calvus
BGC0000495.5	0.41	ribosomal	actagardine	Actinoplanes garbadinensis
BGC0000662.5	0.40	terpene	grixazone A	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001364.3	0.40	ribosomal	cinnamycin B	Actinomadura atramentaria DSM 43919
BGC0000889.5	0.40	other (other)	bagremycin A, bagremycin B	Streptomyces sp. WK-5344
BGC0001294.5	0.40	other (other)	7-prenylisatin	Streptomyces sp. MBT28
BGC0000885.3	0.40	other (other)	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0002621.2	0.40	other (other)	angustmycin A, angustmycin B, angustmycin C, aristeromycin, arabinofuranosyladenine	Streptomyces angustmyceticus
BGC0001592.5	0.40	other (other)	ferroverdin, bagremycin	Streptomyces lunaelactis

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

CRP

Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 16.24 out of 19.26

Confidence: medium

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 23.76 out of 30.11

Confidence: medium

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 25.66 out of 30.11

Confidence: medium

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 25.66 out of 30.11

Confidence: medium

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 24.57 out of 30.11

Confidence: medium

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 24.07 out of 30.11

Confidence: medium

OsdR

Description: Development and stress management regulator
Species: Streptomyces coelicolor
Score: 26.66 out of 30.12

Confidence: medium

Additional weak hits (15):

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 15.66 out of 20.97

Confidence: weak

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 17.02 out of 27.78

Confidence: weak

RutR

Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 20.46 out of 26.85

Confidence: weak

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 15.76 out of 21.84

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 12.73 out of 26.06

Confidence: weak

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 17.82 out of 26.33

Confidence: weak

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 22.20 out of 30.11

Confidence: weak

DasR

Description: N-acetylglucosamine dependent repressor
Species: Streptomyces coelicolor
Score: 19.39 out of 27.04

Confidence: weak

NrdR

Description: Represses ribonucleotide reductase encoding genes
Species: Streptomyces coelicolor
Score: 19.96 out of 27.18

Confidence: weak

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 16.79 out of 19.52

Confidence: weak

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 17.13 out of 31.73

Confidence: weak

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 14.90 out of 18.57

Confidence: weak

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.38 out of 21.84

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 20.26 out of 32.74

Confidence: weak

DmdR1

Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 23.52 out of 36.53

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
CRP	Cyclic AMP receptor protein
CelR	Cellobiose uptake repressor
OsdR	Development and stress management regulator

NZ_CP047419.1 - Region 5 - terpene

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Location: 3,314,635 - 3,338,842 nt. (total: 24,208 nt) Show pHMM detection rules used

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

GTU71_RS15630: dehydrogenase

smcogs: SMCOG1222: dehydrogenase

Hydrolases: hydrolase

GTU71_RS15585: beta-lactamase

smcogs: SMCOG1053: beta-lactamase

Ligases: synthetase

GTU71_RS15625: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000644.3	0.65	terpene	carotenoid	Dietzia sp. CQ4
BGC0000637.3	0.59	terpene	carotenoid	Corynebacterium glutamicum
BGC0000664.5	0.53	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000650.3	0.51	terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000649.3	0.49	terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000648.3	0.49	terpene	carotenoid	Myxococcus xanthus
BGC0002309.2	0.46	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000636.3	0.46	terpene	carotenoid	Brevibacterium linens
BGC0000677.5	0.45	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001911.3	0.43	terpene	raimonol	Streptomyces anulatus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000644.3	0.65	terpene	carotenoid	Dietzia sp. CQ4
BGC0000637.3	0.59	terpene	carotenoid	Corynebacterium glutamicum
BGC0000664.5	0.53	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000650.3	0.51	terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000649.3	0.49	terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000648.3	0.49	terpene	carotenoid	Myxococcus xanthus
BGC0002309.2	0.46	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000636.3	0.46	terpene	carotenoid	Brevibacterium linens
BGC0000677.5	0.45	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001911.3	0.43	terpene	raimonol	Streptomyces anulatus

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
tetraterpene	C40 carotenoid		C40	unknown	unknown

Genes with terpene domains:

GTU71_RS15625: PT_FPPS_like

Domain 1 (17 - 302): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

GTU71_RS15630: PT_phytoene_like

Domain 1 (15 - 289): Prenyltransferase; Phytoene synthase like

Subtype: unknown

Reactions:: FPP → squalene; FPP → diapophytoene; FPP → PSPP; GGPP → phytoene; PSPP → hydroxysqualene

GTU71_RS15635: Lycopene_cycl

Domain 1 (4 - 91): Lycopene cyclase

Reactions:: C40_carotenoid → C40_carotenoid

GTU71_RS16535: Lycopene_cycl

Domain 1 (1 - 92): Lycopene cyclase

Reactions:: C40_carotenoid → C40_carotenoid

Transcription Factor Binding Sites

Binding sites found:

VqsM

Description: Regulator of quorum-sensing signalling systems
Species: Pseudomonas aeruginosa PAO1
Score: 19.46 out of 20.47

Confidence: strong

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 18.33 out of 23.79

Confidence: medium

Additional weak hits (4):

HipB

Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 20.42 out of 33.73

Confidence: weak

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 21.79 out of 30.22

Confidence: weak

DmdR1

Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 24.57 out of 36.53

Confidence: weak

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 18.61 out of 32.93

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PSPP	Presqualene diphosphate

TFBS definitions

Regulator	Description
IolR	Regulator of the inositol catabolism
VqsM	Regulator of quorum-sensing signalling systems