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Overview
1.1
1.2
1.3
1.4
1.5

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP047419.1 (Rathayibacter sp. VKM Ac-2762)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1 | terpene-precursor | 1,249,025 | 1,270,125 |  |
Region 2 | T3PKS | 2,401,056 | 2,442,171 |  |
Region 3 | lanthipeptide-class-ii | 2,711,142 | 2,740,296 |
Region 4 | oligosaccharide | 2,769,125 | 2,811,045 |
Region 5 | terpene | 3,314,635 | 3,338,842 | Low | carotenoid | terpene

NZ_CP047419.1 - Region 1 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,249,025 - 1,270,125 nt. (total: 21,101 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Transferases: acyltransferase
GTU71_RS05960: acyltransferase

smcogs
  SMCOG1141: acyltransferase

Hydrolases: deformylase
GTU71_RS05975: peptide deformylase

smcogs
  SMCOG1275: peptide deformylase

Ligases: ligase synthetase
GTU71_RS05940: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

GTU71_RS05970: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000677.5 |  | 0.42 | terpene | cyclooctatin | Streptomyces melanosporofaciens
BGC0000649.3 |  | 0.40 | terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001910.4 |  | 0.39 | terpene | cyslabdan A, cyslabdan B, cyslabdan C | Streptomyces cyslabdanicus
BGC0001456.3 |  | 0.39 | terpene | isorenieratene | Streptomyces argillaceus
BGC0001483.4 |  | 0.38 | other (other) | 5-isoprenylindole-3-carboxylate β-D-glycosyl ester | Streptomyces sp. RM-5-8
BGC0001911.3 |  | 0.38 | terpene | raimonol | Streptomyces anulatus
BGC0000664.5 |  | 0.38 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000678.5 |  | 0.38 | terpene | pentalenolactone | Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0002348.2 |  | 0.37 | NRPS | aspulvinone E | Aspergillus terreus NIH2624
BGC0000633.3 |  | 0.37 | terpene | carotenoid | Streptomyces avermitilis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000677.5 |  | 0.42 | terpene | cyclooctatin | Streptomyces melanosporofaciens
BGC0000649.3 |  | 0.40 | terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001910.4 |  | 0.39 | terpene | cyslabdan A, cyslabdan B, cyslabdan C | Streptomyces cyslabdanicus
BGC0001456.3 |  | 0.39 | terpene | isorenieratene | Streptomyces argillaceus
BGC0001483.4 |  | 0.38 | other (other) | 5-isoprenylindole-3-carboxylate β-D-glycosyl ester | Streptomyces sp. RM-5-8
BGC0001911.3 |  | 0.38 | terpene | raimonol | Streptomyces anulatus
BGC0000664.5 |  | 0.38 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000678.5 |  | 0.38 | terpene | pentalenolactone | Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0002348.2 |  | 0.37 | NRPS | aspulvinone E | Aspergillus terreus NIH2624
BGC0000633.3 |  | 0.37 | terpene | carotenoid | Streptomyces avermitilis

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP
diterpene precursor |  | GGPP | C20 | acyclic | PP
sesterterpene precursor |  | GFPP | C25 | acyclic | PP
triterpene precursor |  | HPP | C30 | acyclic | PP

Genes with terpene domains:
GTU71_RS05940: PT_FPPS_like
Domain 1 (45 - 365): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: unknown

Reactions:
  IPP, DMAPP → FPP
  IPP, DMAPP → GGPP
  IPP, DMAPP → GFPP
  IPP, DMAPP → HPP

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
No hits above weak threshold.
Weak hits (4):
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 22.68 out of 30.22
Confidence: weak
RutR
Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.66 out of 26.85
Confidence: weak
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 22.68 out of 30.22
Confidence: weak
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 19.28 out of 28.19
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
GFPP | Geranylfarnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
HPP | Hexaprenyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---

NZ_CP047419.1 - Region 2 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,401,056 - 2,442,171 nt. (total: 41,116 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
NRPS/PKS domains
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
GTU71_RS11385: short-chain dehydrogenase/reductase SDR

smcogs
  SMCOG1001: short-chain dehydrogenase/reductase SDR

GTU71_RS11495: short-chain dehydrogenase/reductase SDR

smcogs
  SMCOG1001: short-chain dehydrogenase/reductase SDR

Hydrolases: esterase
GTU71_RS11355: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase

smcogs
  SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase

Lyases: dehydratase
GTU71_RS11370: NAD-dependent epimerase/dehydratase

smcogs
  SMCOG1010: NAD-dependent epimerase/dehydratase

Ligases: synthase
GTU71_RS11390: chalcone and stilbene synthase domain protein

smcogs
  SMCOG1024: chalcone and stilbene synthase domain protein

Translocases: permease
GTU71_RS11440: phenylalanine-specific permease

smcogs
  SMCOG1038: phenylalanine-specific permease

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.3 |  | 0.53 | PKS | 2-methoxy-5-methyl-6-(13-methyltetradecyl)-1,4-benzoquinone, 2-methoxy-5-methyl-6-(13-methyltetradecyl)phenol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001962.3 |  | 0.52 | PKS | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001928.2 |  | 0.48 | other (other) | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0001974.2 |  | 0.46 | other (other) | kainic acid, Kainic acid lactone | Digenea simplex
BGC0002332.2 |  | 0.46 | PKS | 4-hydroxy-6-pentadecylpyran-2-one, 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one, Adipostatin A | Candidatus Entotheonella sp.
BGC0002404.2 |  | 0.45 | other (other) | falcarindiol | Solanum lycopersicum
BGC0001831.3 |  | 0.45 | PKS | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001987.2 |  | 0.43 | PKS | koreenceine A, koreenceine B, koreenceine C, koreenceine D | Pseudomonas koreensis
BGC0000671.3 |  | 0.43 | terpene | momilactone B | Oryza sativa Japonica Group
BGC0002362.3 |  | 0.43 | PKS | loseolamycin A1, loseolamycin A2 | Micromonospora endolithica

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.3 |  | 0.53 | PKS | 2-methoxy-5-methyl-6-(13-methyltetradecyl)-1,4-benzoquinone, 2-methoxy-5-methyl-6-(13-methyltetradecyl)phenol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001962.3 |  | 0.52 | PKS | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001928.2 |  | 0.48 | other (other) | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0001974.2 |  | 0.46 | other (other) | kainic acid, Kainic acid lactone | Digenea simplex
BGC0002332.2 |  | 0.46 | PKS | 4-hydroxy-6-pentadecylpyran-2-one, 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one, Adipostatin A | Candidatus Entotheonella sp.
BGC0002404.2 |  | 0.45 | other (other) | falcarindiol | Solanum lycopersicum
BGC0001831.3 |  | 0.45 | PKS | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001987.2 |  | 0.43 | PKS | koreenceine A, koreenceine B, koreenceine C, koreenceine D | Pseudomonas koreensis
BGC0000671.3 |  | 0.43 | terpene | momilactone B | Oryza sativa Japonica Group
BGC0002362.3 |  | 0.43 | PKS | loseolamycin A1, loseolamycin A2 | Micromonospora endolithica

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
NtrC
Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 21.87 out of 29.72
Confidence: medium
Additional weak hits (9):
MexT
Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 15.56 out of 21.84
Confidence: weak
HexR
Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 20.00 out of 31.73
Confidence: weak
HgtR
Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 18.82 out of 36.54
Confidence: weak
HgtR
Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 20.77 out of 36.54
Confidence: weak
ArcA
Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 14.41 out of 21.55
Confidence: weak
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 21.27 out of 30.22
Confidence: weak
CRP
Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 15.93 out of 19.26
Confidence: weak
LexA variant 2
Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 17.67 out of 24.78
Confidence: weak
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 19.52 out of 28.19
Confidence: weak
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
NtrC | Nitrogen regulatory protein C

NZ_CP047419.1 - Region 3 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,711,142 - 2,740,296 nt. (total: 29,155 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: oxidoreductase
GTU71_RS12800: oxidoreductase

smcogs
  SMCOG1083: oxidoreductase

Transferases: methyltransferase
GTU71_RS12835: methyltransferase

smcogs
  SMCOG1248: methyltransferase

Lyases: cyclase
GTU71_RS12790: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

GTU71_RS12810: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001229.4 |  | 0.65 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000520.5 |  | 0.59 | ribosomal | lacticin 3147 A1, lacticin 3147 A2 | Lactococcus lactis
BGC0000555.3 |  | 0.56 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0002110.3 |  | 0.54 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0000623.3 |  | 0.53 | ribosomal | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0001311.5 |  | 0.53 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0000525.5 |  | 0.53 | ribosomal | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0002663.2 |  | 0.53 | ribosomal | amyloliquecidin GF610 | Bacillus amyloliquefaciens UMAF6639
BGC0001555.4 |  | 0.52 | ribosomal | colicin V | Escherichia coli chi7122
BGC0000517.4 |  | 0.51 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001229.4 |  | 0.65 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000520.5 |  | 0.59 | ribosomal | lacticin 3147 A1, lacticin 3147 A2 | Lactococcus lactis
BGC0000555.3 |  | 0.56 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0002110.3 |  | 0.54 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0000623.3 |  | 0.53 | ribosomal | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0001311.5 |  | 0.53 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0000525.5 |  | 0.53 | ribosomal | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0002663.2 |  | 0.53 | ribosomal | amyloliquecidin GF610 | Bacillus amyloliquefaciens UMAF6639
BGC0001555.4 |  | 0.52 | ribosomal | colicin V | Escherichia coli chi7122
BGC0000517.4 |  | 0.51 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for GTU71_RS12790

GTU71_RS12785
Leader:
MKMTNNADDVLRRTGFVDESHLSDLVAGDRAAGEQEVGAGS
Core:
P V I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
Core with dehydrations:
P V I I Dha A V Dha G Dhb V A Dha A Dhb A V Dha A L V Dhb Dha Dha G L Cys P Dhb F Dha Cys Dhb G E Cys

#### antiSMASH-DB 4.0 matches for GTU71_RS12785

100.0%
NZ_CP047419.1 and 3 others:
NZ_CP047419.1 Lanthipeptides: GTU71_RS12785_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15570_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15570_lanthipeptide
Lanthipeptides: GTU71_RS12785_lanthipeptide
1
P V I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
P V I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
1
P V I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
52.8%
NZ_CP086141.1 and 1 other:
NZ_CP086141.1 Lanthipeptides: LL065_RS24780_lanthipeptide
Lanthipeptides: LL065_RS24780_lanthipeptide
4
I S A V S G T V A S A T A V S A L V T S S G L C P T F S C
32
+S A+S T V A S A T A V S A L T + C T S C
1
V S A I S A T V A S A T A V S A L F T V T S A C-T K S C
28
52.8%
NZ_CP086141.1 and 1 other:
NZ_CP086141.1 Lanthipeptides: LL065_RS24780_lanthipeptide
Lanthipeptides: LL065_RS24780_lanthipeptide
3
I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C
32
++S A+S T V A S A T A V S A L T + C T S C
4
V V S A I S A T V A S A T A V S A L F T V T S A C-T K S C
32
with 78 more sequence matches
Only the first 10 are displayed here.
47.2%
NZ_BQXZ01000001.1 and 1 other:
NZ_BQXZ01000001.1 Lanthipeptides: OCU69_RS05005_lanthipeptide
Lanthipeptides: OCU69_RS05005_lanthipeptide
3
I I S A V S G T V A S A T A V S A L V T S S G L C P T
29
I+S A+S T V A S A T A+S A L T + C T
4
I V S A I S A T V A S A T A I S A L F T V T S A C T T
30
44.4%
NC_017299.1 and 1 other:
NC_017299.1 Lanthipeptides: H04402_RS03100_lanthipeptide
Lanthipeptides: H04402_RS03100_lanthipeptide
7
V S G T V A S A T A V S A L V T S S G L C P T
29
V S T V A S A T A V S A L T + C T
1
V S A T V A S A T A V S A L F T V T S A C T T
23
41.7%
NZ_FQZK01000006.1 and 2 others:
NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13105_lanthipeptide NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13105_lanthipeptide
Lanthipeptides: BUE45_RS13105_lanthipeptide
7
V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
+S T V A S T A+S A C P T C T C
1
I S A T V A S V T A I S A A W G D G--C P T T V C T S R C
28
38.9%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide
Lanthipeptides: BHL26_RS15355_lanthipeptide
3
I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
I V T + T A V S + S S C P+ +C T C
1
I T P T V L A T T G A L T A V S G Y I-S S N T C P S T A C T R A C
33
37.8%
NZ_CM000756.1 and 17 others:
NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptide NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14765_lanthipeptide NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide
Lanthipeptides: BTHUR0011_RS14765_lanthipeptide
9
G T V A S A T A V S A L--V T S S G L C P T F S C T G E C
36
G T A T A+S A+ V T+ C P T +C+ C
6
G T P A I V T A I S A V T A V T A Q S P C P T S A C S K S C
35
36.8%
NC_006322.1 and 7 others:
NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptide NZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptide NZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptide NZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptide NZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptide NZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide NZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide
Lanthipeptides: BLI_RS20290_lanthipeptide
9
G T V A S A T A V S A L V T-S S G L C P T F S C T G E C
36
T +S T ++A V T S+ L C P T C T C
10
A T T S S W T C I T A G V T V S A S L C P T T K C T S R C
38
36.1%
NZ_CP013862.1 and 1 other:
NZ_CP013862.1 Lanthipeptides: AOX59_RS09365_lanthipeptide
Lanthipeptides: AOX59_RS09365_lanthipeptide
10
T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
+V A A V S A L C P T C T +C
11
S V A C G I A V S A L-----F C P T T K C T S Q C
32
36.1%
NZ_CP036019.1 and 7 others:
NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptide NZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptide NZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide NZ_CP036019.1 Lanthipeptides: EXW52_RS27190_lanthipeptide NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptide NZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptide NZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide
Lanthipeptides: EXW52_RS27190_lanthipeptide
7
V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
V S A T + S G L C P T C T +C
3
V S P E T T P A T P T I V V A I S V G L C P T N R C T S K C
32
36.1%
NZ_CP036019.1 and 1 other:
NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide
Lanthipeptides: EXW52_RS27205_lanthipeptide
7
V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
V S A T + S G L C P T C T +C
3
V S P E T T P A T P T I V V A I S V G L C P T T K C T S K C
32
36.1%
NZ_CP047645.1 and 5 others:
NZ_CP047645.1 Lanthipeptides: GSN02_RS17435_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide
Lanthipeptides: GSN02_RS17435_lanthipeptide
3
I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
I I+A++G T + T S+ C P T +C T C
7
I I T A L T G T T F T V T L------S A A S C P T S A C T N L C
34

#### MIBiG 4.0 matches for GTU71_RS12785

35.1%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
6
A V S G T V A S A T A V S A L V---T S S G L C P T F S C T G E C
36
A V+G + A+ A V S+ C P T C T C
4
A V T G L I L G I V A I Q A G V A V G V S A A F C P T T K C T S R C
37
16.7%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
26
L C P T F S C T G E C
36
C P T C T +C
16
F C P T T K C T S K C
26
GTU71_RS12805
Leader:
MSQYDVALFEEIAEQDFDSVAYGA
Core:
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
Core with dehydrations:
Cys Dhb Dhb N Dhb F Dhb L Dha N V L G N Q G G W Cys Dhb L Dhb V E Cys Q P N Cys K

#### antiSMASH-DB 4.0 matches for GTU71_RS12805

100.0%
NZ_CP047419.1 and 3 others:
NZ_CP047419.1 Lanthipeptides: GTU71_RS12805_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptide
Lanthipeptides: GTU71_RS12805_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
30
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
30
86.7%
NZ_BMMP01000005.1 and 3 others:
NZ_BMMP01000005.1 Lanthipeptides: IEY56_RS28370_lanthipeptide NZ_FMHJ01000003.1 Lanthipeptides: H181DRAFT_RS07545_lanthipeptide NZ_FMHJ01000003.1 Lanthipeptides: H181DRAFT_RS07545_lanthipeptide
Lanthipeptides: IEY56_RS28370_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
30
C T T N T F+L S+V L G N G G W C T L T V E C Q P N C
1
C T T N T F S L S D V L G N T G G W C T L T V E C Q P N C N
30
83.3%
NZ_CP107567.1 and 3 others:
NZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptide NZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptide NZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptide
Lanthipeptides: OGH68_RS19760_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S+ L G N Q G G W C T L T E C Q P N C
1
C T T N T F S L S D W L G N Q G G W C T L T K E C Q P N C
29
with 103 more sequence matches
Only the first 10 are displayed here.
83.3%
NZ_QLLX01000002.1 and 1 other:
NZ_QLLX01000002.1 Lanthipeptides: K378_RS05175_lanthipeptide
Lanthipeptides: K378_RS05175_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S+ L N Q G G W C T L T V E C Q P N C
1
C T T N T F S L S D A L T N Q G G W C T L T V E C Q P N C
29
80.0%
NZ_AKXV01000031.1 and 4 others:
NZ_AKXV01000031.1 Lanthipeptides: Y19_RS0109895_lanthipeptide NZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13545_lanthipeptide NZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide NZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide
Lanthipeptides: Y19_RS0109895_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C+T N T F+L S+ L G N Q G G W C T L T E C Q P N C
1
C S T N T F S L S D F L G N Q G G W C T L T K E C Q P N C
29
80.0%
NZ_BNBV01000031.1 and 1 other:
NZ_BNBV01000031.1 Lanthipeptides: IE286_RS22995_lanthipeptide
Lanthipeptides: IE286_RS22995_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S+ L G N G G W C T L T E C Q P N C
1
C T T N T F S L S D A L G N S G G W C T L T K E C Q P N C
29
80.0%
NZ_CP016795.1 and 5 others:
NZ_CP016795.1 Lanthipeptides: BC342_RS18360_lanthipeptide NZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptide NZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptide NZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide NZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide
Lanthipeptides: BC342_RS18360_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
30
C T T N T F+L S+ L G N G G W C T L T E C Q P N C
1
C T T N T F S L S D A L G N H G G W C T L T K E C Q P N C S
30
80.0%
NZ_CP043317.1 and 1 other:
NZ_CP043317.1 Lanthipeptides: FYC74_RS17680_lanthipeptide
Lanthipeptides: FYC74_RS17680_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
30
C T T N T F+L S+ L G N G G W C T L T E C Q P N C
1
C T T N T F S L S D S L G N H G G W C T L T K E C Q P N C S
30
80.0%
NZ_CP084530.1 and 1 other:
NZ_CP084530.1 Lanthipeptides: LDO05_RS02075_lanthipeptide
Lanthipeptides: LDO05_RS02075_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F T L S N L G N G G W C T L T E C Q +C
1
C T T N T F T L S N Y L G N N G G W C T L T K E C Q R S C
29
80.0%
NZ_JAASAG010000001.1 and 1 other:
NZ_JAASAG010000001.1 Lanthipeptides: HCC61_RS30395_lanthipeptide
Lanthipeptides: HCC61_RS30395_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S+ L N G G W C T L T V E C Q P N C
1
C T T N T F S L S D A L T N T G G W C T L T V E C Q P N C
29
76.7%
NZ_BJTV01000004.1 and 1 other:
NZ_BJTV01000004.1 Lanthipeptides: TNCT1_RS10200_lanthipeptide
Lanthipeptides: TNCT1_RS10200_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S+ L G N G G W C T L T E C Q N C
1
C T T N T F S L S D A L G N H G G W C T L T K E C Q A N C
29
76.7%
NZ_BNCA01000011.1 and 1 other:
NZ_BNCA01000011.1 Lanthipeptides: IE314_RS15865_lanthipeptide
Lanthipeptides: IE314_RS15865_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S+ +G N G G W C T L T E C Q P N C
1
C T T N T F S L S D A V G N H G G W C T L T K E C Q P N C
29
76.7%
NZ_LT985747.1 and 1 other:
NZ_LT985747.1 Lanthipeptides: C8268_RS00165_lanthipeptide
Lanthipeptides: C8268_RS00165_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F T L S+ L G N+G G W C T L T E C Q +C
1
C T T N T F T L S D Y L G N K G G W C T L T K E C Q R S C
29

#### MIBiG 4.0 matches for GTU71_RS12805

83.3%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S N L G N G G W C T L T E C Q P N C
1
C T T N T F S L S N A L G N N G G W C T L T K E C Q P N C
29
46.7%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
6
F T L S N V L G N Q G G W C T L T V E C Q P N C
29
+ +S L G N+G +C T L T V E C P+C
4
Y N I S C R L G N K G A Y C T L T V E C M P S C
27
23.1%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
C T L T V E C Q P N C
29
C T L+ E C Q P N C
28
C T L S K E C Q P N C
38
with 1 more sequence matches
11.8%
BGC0000535.4 (ADJ56352.1):
Lanthipeptide: nisin A
25
C Q P N C K
30
C P C K
7
C T P G C K
12
allorf_2720111_2720311
Leader:
MTSPGA
Core:
R N C L P A E S R V H P L G Q P P I P L S G L L L P L R P F L G S I V Q S S S G L H R S R S T S G D L L V G W T G G C P
Core with dehydrations:
R N Cys L P A E Dha R V H P L G Q P P I P L Dha G L L L P L R P F L G Dha I V Q Dha Dha Dha G L H R Dha R Dha Dhb Dha G D L L V G W Dhb G G Cys P

#### antiSMASH-DB 4.0 matches for allorf_2720111_2720311

100.0%
NZ_CP047419.1 and 3 others:
NZ_CP047419.1 Lanthipeptides: allorf_2720111_2720311_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: allorf_08713_08913_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: allorf_08713_08913_lanthipeptide
Lanthipeptides: allorf_2720111_2720311_lanthipeptide
1
R N C L P A E S R V H P L G Q P P I P L S G L L L P L R P F L G S I V Q S S S G L H R S R S T S G D L L V G W T G G C P
60
R N C L P A E S R V H P L G Q P P I P L S G L L L P L R P F L G S I V Q S S S G L H R S R S T S G D L L V G W T G G C P
1
R N C L P A E S R V H P L G Q P P I P L S G L L L P L R P F L G S I V Q S S S G L H R S R S T S G D L L V G W T G G C P
60
16.7%
NZ_CP094446.1:
Lanthipeptides: L3476_RS23825_lanthipeptide
8
S R V H P L G Q P P I P L S G L L L P L R P F L G S I V Q S S S G L
41
S V P G P +S + +P + +I + S G+
1
S D V E P R G T P A T I V S A V T R S S K P C I S A I G S A I S G I
34
13.3%
NZ_CP031447.1:
Lanthipeptides: allorf_0156643_0156801_lanthipeptide
5
P A E S R V H P L G Q P P I
18
P A E R H L P P+
15
P A E V R A H L L D S P P V
28
with 1 more sequence matches
11.7%
NZ_MKZR01000001.1:
Lanthipeptides: allorf_2981606_2981719_lanthipeptide
1
R N C L P A E S R V H P L G Q P P I P
19
R+ +P + P L +P P+P
7
R S A I P V Y Y L L R P L N R P P M P
25

#### Lanthipeptide(s) for GTU71_RS12810

GTU71_RS12785
Leader:
MKMTNNADDVLRRTGFVDESHLSDLVAGDRAAGEQEVGAGS
Core:
P V I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
Core with dehydrations:
P V I I Dha A V Dha G Dhb V A Dha A Dhb A V Dha A L V Dhb Dha Dha G L Cys P Dhb F Dha Cys Dhb G E Cys

#### antiSMASH-DB 4.0 matches for GTU71_RS12785

100.0%
NZ_CP047419.1 and 3 others:
NZ_CP047419.1 Lanthipeptides: GTU71_RS12785_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15570_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15570_lanthipeptide
Lanthipeptides: GTU71_RS12785_lanthipeptide
1
P V I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
P V I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
1
P V I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
52.8%
NZ_CP086141.1 and 1 other:
NZ_CP086141.1 Lanthipeptides: LL065_RS24780_lanthipeptide
Lanthipeptides: LL065_RS24780_lanthipeptide
4
I S A V S G T V A S A T A V S A L V T S S G L C P T F S C
32
+S A+S T V A S A T A V S A L T + C T S C
1
V S A I S A T V A S A T A V S A L F T V T S A C-T K S C
28
52.8%
NZ_CP086141.1 and 1 other:
NZ_CP086141.1 Lanthipeptides: LL065_RS24780_lanthipeptide
Lanthipeptides: LL065_RS24780_lanthipeptide
3
I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C
32
++S A+S T V A S A T A V S A L T + C T S C
4
V V S A I S A T V A S A T A V S A L F T V T S A C-T K S C
32
with 78 more sequence matches
Only the first 10 are displayed here.
47.2%
NZ_BQXZ01000001.1 and 1 other:
NZ_BQXZ01000001.1 Lanthipeptides: OCU69_RS05005_lanthipeptide
Lanthipeptides: OCU69_RS05005_lanthipeptide
3
I I S A V S G T V A S A T A V S A L V T S S G L C P T
29
I+S A+S T V A S A T A+S A L T + C T
4
I V S A I S A T V A S A T A I S A L F T V T S A C T T
30
44.4%
NC_017299.1 and 1 other:
NC_017299.1 Lanthipeptides: H04402_RS03100_lanthipeptide
Lanthipeptides: H04402_RS03100_lanthipeptide
7
V S G T V A S A T A V S A L V T S S G L C P T
29
V S T V A S A T A V S A L T + C T
1
V S A T V A S A T A V S A L F T V T S A C T T
23
41.7%
NZ_FQZK01000006.1 and 2 others:
NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13105_lanthipeptide NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13105_lanthipeptide
Lanthipeptides: BUE45_RS13105_lanthipeptide
7
V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
+S T V A S T A+S A C P T C T C
1
I S A T V A S V T A I S A A W G D G--C P T T V C T S R C
28
38.9%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide
Lanthipeptides: BHL26_RS15355_lanthipeptide
3
I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
I V T + T A V S + S S C P+ +C T C
1
I T P T V L A T T G A L T A V S G Y I-S S N T C P S T A C T R A C
33
37.8%
NZ_CM000756.1 and 17 others:
NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptide NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14765_lanthipeptide NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide
Lanthipeptides: BTHUR0011_RS14765_lanthipeptide
9
G T V A S A T A V S A L--V T S S G L C P T F S C T G E C
36
G T A T A+S A+ V T+ C P T +C+ C
6
G T P A I V T A I S A V T A V T A Q S P C P T S A C S K S C
35
36.8%
NC_006322.1 and 7 others:
NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptide NZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptide NZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptide NZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptide NZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptide NZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide NZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide
Lanthipeptides: BLI_RS20290_lanthipeptide
9
G T V A S A T A V S A L V T-S S G L C P T F S C T G E C
36
T +S T ++A V T S+ L C P T C T C
10
A T T S S W T C I T A G V T V S A S L C P T T K C T S R C
38
36.1%
NZ_CP013862.1 and 1 other:
NZ_CP013862.1 Lanthipeptides: AOX59_RS09365_lanthipeptide
Lanthipeptides: AOX59_RS09365_lanthipeptide
10
T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
+V A A V S A L C P T C T +C
11
S V A C G I A V S A L-----F C P T T K C T S Q C
32
36.1%
NZ_CP036019.1 and 7 others:
NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptide NZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptide NZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide NZ_CP036019.1 Lanthipeptides: EXW52_RS27190_lanthipeptide NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptide NZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptide NZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide
Lanthipeptides: EXW52_RS27190_lanthipeptide
7
V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
V S A T + S G L C P T C T +C
3
V S P E T T P A T P T I V V A I S V G L C P T N R C T S K C
32
36.1%
NZ_CP036019.1 and 1 other:
NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide
Lanthipeptides: EXW52_RS27205_lanthipeptide
7
V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
V S A T + S G L C P T C T +C
3
V S P E T T P A T P T I V V A I S V G L C P T T K C T S K C
32
36.1%
NZ_CP047645.1 and 5 others:
NZ_CP047645.1 Lanthipeptides: GSN02_RS17435_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide
Lanthipeptides: GSN02_RS17435_lanthipeptide
3
I I S A V S G T V A S A T A V S A L V T S S G L C P T F S C T G E C
36
I I+A++G T + T S+ C P T +C T C
7
I I T A L T G T T F T V T L------S A A S C P T S A C T N L C
34

#### MIBiG 4.0 matches for GTU71_RS12785

35.1%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
6
A V S G T V A S A T A V S A L V---T S S G L C P T F S C T G E C
36
A V+G + A+ A V S+ C P T C T C
4
A V T G L I L G I V A I Q A G V A V G V S A A F C P T T K C T S R C
37
16.7%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
26
L C P T F S C T G E C
36
C P T C T +C
16
F C P T T K C T S K C
26
GTU71_RS12805
Leader:
MSQYDVALFEEIAEQDFDSVAYGA
Core:
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
Core with dehydrations:
Cys Dhb Dhb N Dhb F Dhb L Dha N V L G N Q G G W Cys Dhb L Dhb V E Cys Q P N Cys K

#### antiSMASH-DB 4.0 matches for GTU71_RS12805

100.0%
NZ_CP047419.1 and 3 others:
NZ_CP047419.1 Lanthipeptides: GTU71_RS12805_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptide
Lanthipeptides: GTU71_RS12805_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
30
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
30
86.7%
NZ_BMMP01000005.1 and 3 others:
NZ_BMMP01000005.1 Lanthipeptides: IEY56_RS28370_lanthipeptide NZ_FMHJ01000003.1 Lanthipeptides: H181DRAFT_RS07545_lanthipeptide NZ_FMHJ01000003.1 Lanthipeptides: H181DRAFT_RS07545_lanthipeptide
Lanthipeptides: IEY56_RS28370_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
30
C T T N T F+L S+V L G N G G W C T L T V E C Q P N C
1
C T T N T F S L S D V L G N T G G W C T L T V E C Q P N C N
30
83.3%
NZ_CP107567.1 and 3 others:
NZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptide NZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptide NZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptide
Lanthipeptides: OGH68_RS19760_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S+ L G N Q G G W C T L T E C Q P N C
1
C T T N T F S L S D W L G N Q G G W C T L T K E C Q P N C
29
with 103 more sequence matches
Only the first 10 are displayed here.
83.3%
NZ_QLLX01000002.1 and 1 other:
NZ_QLLX01000002.1 Lanthipeptides: K378_RS05175_lanthipeptide
Lanthipeptides: K378_RS05175_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S+ L N Q G G W C T L T V E C Q P N C
1
C T T N T F S L S D A L T N Q G G W C T L T V E C Q P N C
29
80.0%
NZ_AKXV01000031.1 and 4 others:
NZ_AKXV01000031.1 Lanthipeptides: Y19_RS0109895_lanthipeptide NZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13545_lanthipeptide NZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide NZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide
Lanthipeptides: Y19_RS0109895_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C+T N T F+L S+ L G N Q G G W C T L T E C Q P N C
1
C S T N T F S L S D F L G N Q G G W C T L T K E C Q P N C
29
80.0%
NZ_BNBV01000031.1 and 1 other:
NZ_BNBV01000031.1 Lanthipeptides: IE286_RS22995_lanthipeptide
Lanthipeptides: IE286_RS22995_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S+ L G N G G W C T L T E C Q P N C
1
C T T N T F S L S D A L G N S G G W C T L T K E C Q P N C
29
80.0%
NZ_CP016795.1 and 5 others:
NZ_CP016795.1 Lanthipeptides: BC342_RS18360_lanthipeptide NZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptide NZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptide NZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide NZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide
Lanthipeptides: BC342_RS18360_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
30
C T T N T F+L S+ L G N G G W C T L T E C Q P N C
1
C T T N T F S L S D A L G N H G G W C T L T K E C Q P N C S
30
80.0%
NZ_CP043317.1 and 1 other:
NZ_CP043317.1 Lanthipeptides: FYC74_RS17680_lanthipeptide
Lanthipeptides: FYC74_RS17680_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C K
30
C T T N T F+L S+ L G N G G W C T L T E C Q P N C
1
C T T N T F S L S D S L G N H G G W C T L T K E C Q P N C S
30
80.0%
NZ_CP084530.1 and 1 other:
NZ_CP084530.1 Lanthipeptides: LDO05_RS02075_lanthipeptide
Lanthipeptides: LDO05_RS02075_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F T L S N L G N G G W C T L T E C Q +C
1
C T T N T F T L S N Y L G N N G G W C T L T K E C Q R S C
29
80.0%
NZ_JAASAG010000001.1 and 1 other:
NZ_JAASAG010000001.1 Lanthipeptides: HCC61_RS30395_lanthipeptide
Lanthipeptides: HCC61_RS30395_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S+ L N G G W C T L T V E C Q P N C
1
C T T N T F S L S D A L T N T G G W C T L T V E C Q P N C
29
76.7%
NZ_BJTV01000004.1 and 1 other:
NZ_BJTV01000004.1 Lanthipeptides: TNCT1_RS10200_lanthipeptide
Lanthipeptides: TNCT1_RS10200_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S+ L G N G G W C T L T E C Q N C
1
C T T N T F S L S D A L G N H G G W C T L T K E C Q A N C
29
76.7%
NZ_BNCA01000011.1 and 1 other:
NZ_BNCA01000011.1 Lanthipeptides: IE314_RS15865_lanthipeptide
Lanthipeptides: IE314_RS15865_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S+ +G N G G W C T L T E C Q P N C
1
C T T N T F S L S D A V G N H G G W C T L T K E C Q P N C
29
76.7%
NZ_LT985747.1 and 1 other:
NZ_LT985747.1 Lanthipeptides: C8268_RS00165_lanthipeptide
Lanthipeptides: C8268_RS00165_lanthipeptide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F T L S+ L G N+G G W C T L T E C Q +C
1
C T T N T F T L S D Y L G N K G G W C T L T K E C Q R S C
29

#### MIBiG 4.0 matches for GTU71_RS12805

83.3%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
1
C T T N T F T L S N V L G N Q G G W C T L T V E C Q P N C
29
C T T N T F+L S N L G N G G W C T L T E C Q P N C
1
C T T N T F S L S N A L G N N G G W C T L T K E C Q P N C
29
46.7%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
6
F T L S N V L G N Q G G W C T L T V E C Q P N C
29
+ +S L G N+G +C T L T V E C P+C
4
Y N I S C R L G N K G A Y C T L T V E C M P S C
27
23.1%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
C T L T V E C Q P N C
29
C T L+ E C Q P N C
28
C T L S K E C Q P N C
38
with 1 more sequence matches
11.8%
BGC0000535.4 (ADJ56352.1):
Lanthipeptide: nisin A
25
C Q P N C K
30
C P C K
7
C T P G C K
12
allorf_2720111_2720311
Leader:
MTSPGA
Core:
R N C L P A E S R V H P L G Q P P I P L S G L L L P L R P F L G S I V Q S S S G L H R S R S T S G D L L V G W T G G C P
Core with dehydrations:
R N Cys L P A E Dha R V H P L G Q P P I P L Dha G L L L P L R P F L G Dha I V Q Dha Dha Dha G L H R Dha R Dha Dhb Dha G D L L V G W Dhb G G Cys P

#### antiSMASH-DB 4.0 matches for allorf_2720111_2720311

100.0%
NZ_CP047419.1 and 3 others:
NZ_CP047419.1 Lanthipeptides: allorf_2720111_2720311_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: allorf_08713_08913_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: allorf_08713_08913_lanthipeptide
Lanthipeptides: allorf_2720111_2720311_lanthipeptide
1
R N C L P A E S R V H P L G Q P P I P L S G L L L P L R P F L G S I V Q S S S G L H R S R S T S G D L L V G W T G G C P
60
R N C L P A E S R V H P L G Q P P I P L S G L L L P L R P F L G S I V Q S S S G L H R S R S T S G D L L V G W T G G C P
1
R N C L P A E S R V H P L G Q P P I P L S G L L L P L R P F L G S I V Q S S S G L H R S R S T S G D L L V G W T G G C P
60
16.7%
NZ_CP094446.1:
Lanthipeptides: L3476_RS23825_lanthipeptide
8
S R V H P L G Q P P I P L S G L L L P L R P F L G S I V Q S S S G L
41
S V P G P +S + +P + +I + S G+
1
S D V E P R G T P A T I V S A V T R S S K P C I S A I G S A I S G I
34
13.3%
NZ_CP031447.1:
Lanthipeptides: allorf_0156643_0156801_lanthipeptide
5
P A E S R V H P L G Q P P I
18
P A E R H L P P+
15
P A E V R A H L L D S P P V
28
with 1 more sequence matches
11.7%
NZ_MKZR01000001.1:
Lanthipeptides: allorf_2981606_2981719_lanthipeptide
1
R N C L P A E S R V H P L G Q P P I P
19
R+ +P + P L +P P+P
7
R S A I P V Y Y L L R P L N R P P M P
25

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.35 out of 23.79
Confidence: medium
Additional weak hits (9):
ANR
Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 19.32 out of 26.33
Confidence: weak
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 15.81 out of 29.38
Confidence: weak
ANR
Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 19.70 out of 26.33
Confidence: weak
LexA variant 1
Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 20.00 out of 29.65
Confidence: weak
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 16.68 out of 29.25
Confidence: weak
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 17.57 out of 28.19
Confidence: weak
LexA variant 1
Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 20.49 out of 29.65
Confidence: weak
LexA variant 1
Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 19.75 out of 29.65
Confidence: weak
LexA variant 1
Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 19.75 out of 29.65
Confidence: weak
Lanthipeptides
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

GTU71_RS12785 - Class II
  Cleavage pHMM score: -3.20
  RODEO score: 0
  Monoisotopic mass: 3169.6 Da
  Molecular weight: 3171.6 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3189.6 Da N = 1
    3207.7 Da N = 2
    3225.7 Da N = 3
    3243.7 Da N = 4
    3261.7 Da N = 5
    3279.7 Da N = 6
    3297.8 Da N = 7
    3315.8 Da N = 8
    3333.8 Da N = 9
GTU71_RS12805 - Class II
  Cleavage pHMM score: -3.60
  RODEO score: 0
  Monoisotopic mass: 3105.4 Da
  Molecular weight: 3107.5 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3125.5 Da N = 1
    3143.5 Da N = 2
    3161.6 Da N = 3
allorf_2720111_2720311 - Class II
  Cleavage pHMM score: -6.80
  RODEO score: 0
  Monoisotopic mass: 6084.3 Da
  Molecular weight: 6088.0 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    6106.0 Da N = 1
    6124.0 Da N = 2
    6142.0 Da N = 3
    6160.1 Da N = 4
    6178.1 Da N = 5
    6196.1 Da N = 6
    6214.1 Da N = 7
    6232.1 Da N = 8
    6250.2 Da N = 9
GTU71_RS12785 - Class II
  Cleavage pHMM score: -3.20
  RODEO score: 0
  Monoisotopic mass: 3169.6 Da
  Molecular weight: 3171.6 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3189.6 Da N = 1
    3207.7 Da N = 2
    3225.7 Da N = 3
    3243.7 Da N = 4
    3261.7 Da N = 5
    3279.7 Da N = 6
    3297.8 Da N = 7
    3315.8 Da N = 8
    3333.8 Da N = 9
GTU71_RS12805 - Class II
  Cleavage pHMM score: -3.60
  RODEO score: 0
  Monoisotopic mass: 3105.4 Da
  Molecular weight: 3107.5 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3125.5 Da N = 1
    3143.5 Da N = 2
    3161.6 Da N = 3
allorf_2720111_2720311 - Class II
  Cleavage pHMM score: -6.80
  RODEO score: 0
  Monoisotopic mass: 6084.3 Da
  Molecular weight: 6088.0 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    6106.0 Da N = 1
    6124.0 Da N = 2
    6142.0 Da N = 3
    6160.1 Da N = 4
    6178.1 Da N = 5
    6196.1 Da N = 6
    6214.1 Da N = 7
    6232.1 Da N = 8
    6250.2 Da N = 9

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
IolR | Regulator of the inositol catabolism

NZ_CP047419.1 - Region 4 - oligosaccharide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,769,125 - 2,811,045 nt. (total: 41,921 nt) Show pHMM detection rules used
oligosaccharide: (repeatable(3, [DUF1205, Glyco_transf_28, Glycos_transf_1, Glycos_transf_2, MGT]) and minscore(MGT, 150))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
binding site
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
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KnownClusterBlast
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TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
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Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase oxidase
GTU71_RS13075: FAD linked oxidase domain protein

smcogs
  SMCOG1138: FAD linked oxidase domain protein

GTU71_RS13095: acyl-CoA dehydrogenase type 2

smcogs
  SMCOG1191: acyl-CoA dehydrogenase type 2

Transferases: glycosyltransferase
GTU71_RS13050: glycosyltransferase

smcogs
  SMCOG1102: glycosyltransferase

GTU71_RS13080: glycosyltransferase, MGT family

smcogs
  SMCOG1062: glycosyltransferase, MGT family

Hydrolases: hydrolase
GTU71_RS13040: metallo-beta-lactamase family protein

smcogs
  SMCOG1170: metallo-beta-lactamase family protein

Translocases: transporter
GTU71_RS13020: sugar-binding lipoprotein

smcogs
  SMCOG1143: sugar-binding lipoprotein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | oligosaccharide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000277.5 |  | 0.46 | PKS | urdamycin | Streptomyces fradiae
BGC0001387.5 |  | 0.42 | other (other) | nucleocidin | Streptomyces calvus
BGC0000495.5 |  | 0.41 | ribosomal | actagardine | Actinoplanes garbadinensis
BGC0000662.5 |  | 0.40 | terpene | grixazone A | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001364.3 |  | 0.40 | ribosomal | cinnamycin B | Actinomadura atramentaria DSM 43919
BGC0000889.5 |  | 0.40 | other (other) | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0001294.5 |  | 0.40 | other (other) | 7-prenylisatin | Streptomyces sp. MBT28
BGC0000885.3 |  | 0.40 | other (other) | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0002621.2 |  | 0.40 | other (other) | angustmycin A, angustmycin B, angustmycin C, aristeromycin, arabinofuranosyladenine | Streptomyces angustmyceticus
BGC0001592.5 |  | 0.40 | other (other) | ferroverdin, bagremycin | Streptomyces lunaelactis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000277.5 |  | 0.46 | PKS | urdamycin | Streptomyces fradiae
BGC0001387.5 |  | 0.42 | other (other) | nucleocidin | Streptomyces calvus
BGC0000495.5 |  | 0.41 | ribosomal | actagardine | Actinoplanes garbadinensis
BGC0000662.5 |  | 0.40 | terpene | grixazone A | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001364.3 |  | 0.40 | ribosomal | cinnamycin B | Actinomadura atramentaria DSM 43919
BGC0000889.5 |  | 0.40 | other (other) | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0001294.5 |  | 0.40 | other (other) | 7-prenylisatin | Streptomyces sp. MBT28
BGC0000885.3 |  | 0.40 | other (other) | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0002621.2 |  | 0.40 | other (other) | angustmycin A, angustmycin B, angustmycin C, aristeromycin, arabinofuranosyladenine | Streptomyces angustmyceticus
BGC0001592.5 |  | 0.40 | other (other) | ferroverdin, bagremycin | Streptomyces lunaelactis

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CRP
Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 16.24 out of 19.26
Confidence: medium
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 23.76 out of 30.11
Confidence: medium
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 25.66 out of 30.11
Confidence: medium
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 25.66 out of 30.11
Confidence: medium
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 24.57 out of 30.11
Confidence: medium
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 24.07 out of 30.11
Confidence: medium
OsdR
Description: Development and stress management regulator
Species: Streptomyces coelicolor
Score: 26.66 out of 30.12
Confidence: medium
Additional weak hits (15):
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 15.66 out of 20.97
Confidence: weak
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 17.02 out of 27.78
Confidence: weak
RutR
Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 20.46 out of 26.85
Confidence: weak
MexT
Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 15.76 out of 21.84
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 12.73 out of 26.06
Confidence: weak
ANR
Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 17.82 out of 26.33
Confidence: weak
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 22.20 out of 30.11
Confidence: weak
DasR
Description: N-acetylglucosamine dependent repressor
Species: Streptomyces coelicolor
Score: 19.39 out of 27.04
Confidence: weak
NrdR
Description: Represses ribonucleotide reductase encoding genes
Species: Streptomyces coelicolor
Score: 19.96 out of 27.18
Confidence: weak
AfsQ1
Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 16.79 out of 19.52
Confidence: weak
HexR
Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 17.13 out of 31.73
Confidence: weak
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 14.90 out of 18.57
Confidence: weak
MexT
Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.38 out of 21.84
Confidence: weak
FuR variant 2
Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 20.26 out of 32.74
Confidence: weak
DmdR1
Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 23.52 out of 36.53
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CRP | Cyclic AMP receptor protein
CelR | Cellobiose uptake repressor
OsdR | Development and stress management regulator

NZ_CP047419.1 - Region 5 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,314,635 - 3,338,842 nt. (total: 24,208 nt) Show pHMM detection rules used
terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
GTU71_RS15630: dehydrogenase

smcogs
  SMCOG1222: dehydrogenase

Hydrolases: hydrolase
GTU71_RS15585: beta-lactamase

smcogs
  SMCOG1053: beta-lactamase

Ligases: synthetase
GTU71_RS15625: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000644.3 |  | 0.65 | terpene | carotenoid | Dietzia sp. CQ4
BGC0000637.3 |  | 0.59 | terpene | carotenoid | Corynebacterium glutamicum
BGC0000664.5 |  | 0.53 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000650.3 |  | 0.51 | terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000649.3 |  | 0.49 | terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000648.3 |  | 0.49 | terpene | carotenoid | Myxococcus xanthus
BGC0002309.2 |  | 0.46 | terpene | cattleyene | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000636.3 |  | 0.46 | terpene | carotenoid | Brevibacterium linens
BGC0000677.5 |  | 0.45 | terpene | cyclooctatin | Streptomyces melanosporofaciens
BGC0001911.3 |  | 0.43 | terpene | raimonol | Streptomyces anulatus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000644.3 |  | 0.65 | terpene | carotenoid | Dietzia sp. CQ4
BGC0000637.3 |  | 0.59 | terpene | carotenoid | Corynebacterium glutamicum
BGC0000664.5 |  | 0.53 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000650.3 |  | 0.51 | terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000649.3 |  | 0.49 | terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000648.3 |  | 0.49 | terpene | carotenoid | Myxococcus xanthus
BGC0002309.2 |  | 0.46 | terpene | cattleyene | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000636.3 |  | 0.46 | terpene | carotenoid | Brevibacterium linens
BGC0000677.5 |  | 0.45 | terpene | cyclooctatin | Streptomyces melanosporofaciens
BGC0001911.3 |  | 0.43 | terpene | raimonol | Streptomyces anulatus

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
tetraterpene | C40 carotenoid |  | C40 | unknown | unknown

Genes with terpene domains:
GTU71_RS15625: PT_FPPS_like
Domain 1 (17 - 302): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: unknown

Reactions:
  IPP, DMAPP → FPP
  IPP, DMAPP → GGPP
  IPP, DMAPP → GFPP
  IPP, DMAPP → HPP

GTU71_RS15630: PT_phytoene_like
Domain 1 (15 - 289): Prenyltransferase; Phytoene synthase like
Subtype: unknown

Reactions:
  FPP → squalene
  FPP → diapophytoene
  FPP → PSPP
  GGPP → phytoene
  PSPP → hydroxysqualene

GTU71_RS15635: Lycopene_cycl
Domain 1 (4 - 91): Lycopene cyclase

Reactions:
  C40_carotenoid → C40_carotenoid

GTU71_RS16535: Lycopene_cycl
Domain 1 (1 - 92): Lycopene cyclase

Reactions:
  C40_carotenoid → C40_carotenoid

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
VqsM
Description: Regulator of quorum-sensing signalling systems
Species: Pseudomonas aeruginosa PAO1
Score: 19.46 out of 20.47
Confidence: strong
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 18.33 out of 23.79
Confidence: medium
Additional weak hits (4):
HipB
Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 20.42 out of 33.73
Confidence: weak
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 21.79 out of 30.22
Confidence: weak
DmdR1
Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 24.57 out of 36.53
Confidence: weak
LexA variant 3
Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 18.61 out of 32.93
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
GFPP | Geranylfarnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
HPP | Hexaprenyl diphosphate
IPP | Isopentenyl diphosphate
PSPP | Presqualene diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
IolR | Regulator of the inositol catabolism
VqsM | Regulator of quorum-sensing signalling systems