GCF_004798665.1 - 2 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP039292.1 (Actinomyces procaprae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	lanthipeptide-class-ii	70,303	98,115
Region 2	terpene-precursor	1,838,244	1,859,425

NZ_CP039292.1 - Region 1 - lanthipeptide-class-ii

Download region GenBank file

Download region SVG

Location: 70,303 - 98,115 nt. (total: 27,813 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Lyases: cyclase

E4J16_RS00330: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

E4J16_RS00340: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001229.4	0.64	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000517.4	0.60	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0002110.3	0.59	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0000520.5	0.55	ribosomal	lacticin 3147 A1, lacticin 3147 A2	Lactococcus lactis
BGC0000552.3	0.53	ribosomal	SmbA, SmbB	Streptococcus mutans
BGC0000555.3	0.53	ribosomal	staphylococcin C55 α, staphylococcin C55 β	Staphylococcus aureus
BGC0000528.5	0.52	ribosomal	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001311.5	0.52	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0002005.2	0.51	ribosomal	RaxX	Xanthomonas oryzae pv. oryzae
BGC0000590.5	0.51	ribosomal	microcin N	Escherichia coli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001229.4	0.64	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000517.4	0.60	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0002110.3	0.59	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0000520.5	0.55	ribosomal	lacticin 3147 A1, lacticin 3147 A2	Lactococcus lactis
BGC0000552.3	0.53	ribosomal	SmbA, SmbB	Streptococcus mutans
BGC0000555.3	0.53	ribosomal	staphylococcin C55 α, staphylococcin C55 β	Staphylococcus aureus
BGC0000528.5	0.52	ribosomal	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001311.5	0.52	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0002005.2	0.51	ribosomal	RaxX	Xanthomonas oryzae pv. oryzae
BGC0000590.5	0.51	ribosomal	microcin N	Escherichia coli

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for E4J16_RS00330

E4J16_RS14990

Leader:

MTHENLTGTYTASELEELNDISAYG

Core:

GTTPSSWPCGIGITTTICPTAVCTSKCR

Core with dehydrations:

GDhbDhbPDhaDhaWPCysGIGIDhbDhbDhbICysPDhbAVCysDhbDhaKCysR

antiSMASH-DB 4.0 matches for E4J16_RS14990

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: E4J16_RS14990_lanthipeptide

Lanthipeptides: E4J16_RS14990_lanthipeptide

GTTPSSWPCGIGITTTICPTAVCTSKCR

89.3%

NZ_CP025249.1and 1 other:

NZ_CP025249.1 Lanthipeptides: CWT12_RS00390_lanthipeptide

Lanthipeptides: CWT12_RS00390_lanthipeptide

GTTPSSWPCGIGITTTICPTAVCTSKCR

GTTPSSWPCGIGITTT+CPTA C+SKCR

GTTPSSWPCGIGITTTVCPTAACSSKCR

50.0%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS18310_lanthipeptide

SSWPCGIGITTTI----CPTAVCTSKC

++ PC +GIT TI CPT CTS+C

TTLPC-VGITVTISVSMCPTTKCTSQC

with 81 more sequence matches

Only the first 10 are displayed here.

46.9%

NC_021362.1and 29 others:

NC_021362.1 Lanthipeptides: BALI_RS00915_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07475_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07475_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20090_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20090_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00915_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00915_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01010_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01010_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01010_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01010_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01010_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01010_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20270_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20270_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03665_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03665_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19045_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19045_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16135_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16135_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11925_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11925_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01510_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01510_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00070_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00070_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21810_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21810_lanthipeptide

Lanthipeptides: BALI_RS00915_lanthipeptide

TTPSSWPCGIGITTTICPTAVCTSKC

TTPSS PCG +T CP+ CTS C

TTPSSLPCGTLVTAVWCPSNACTSDC

46.9%

NZ_CP006058.1and 25 others:

NZ_CP006058.1 Lanthipeptides: BAMY6639_RS19790_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptideNZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptideNZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptide

Lanthipeptides: BAMY6639_RS19790_lanthipeptide

TTPSSWPCGIGITTTICPTAVCTSKC

TTPSS PCG+ +T CP+ CTS C

TTPSSLPCGVFVTAAFCPSTKCTSSC

46.9%

NZ_CP013862.1and 1 other:

NZ_CP013862.1 Lanthipeptides: AOX59_RS09365_lanthipeptide

Lanthipeptides: AOX59_RS09365_lanthipeptide

TTPSSWPCGIGITTTICPTAVCTSKC

TTPSS CGI ++ CPT CTS+C

TTPSSVACGIAVSALFCPTTKCTSQC

46.4%

NZ_CP084530.1and 1 other:

NZ_CP084530.1 Lanthipeptides: LDO05_RS02090_lanthipeptide

Lanthipeptides: LDO05_RS02090_lanthipeptide

TPSSWPCGIGITTTICPTAVCTSKC

T SSW CG+ + CP+ CTSKC

TTSSWICGVA-SAAFCPSTACTSKC

45.5%

NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21840_lanthipeptide

Lanthipeptides: CN325_RS21840_lanthipeptide

TPSSWPCGIGITTTI----CPTAVCTSKC

T ++ PCGIG T TI CPT+ CT +C

TSTTVPCGIGSTITISIAYCPTSKCTERC

43.6%

NZ_CP009280.1and 1 other:

NZ_CP009280.1 Lanthipeptides: P40081_RS37160_lanthipeptide

Lanthipeptides: P40081_RS37160_lanthipeptide

TPSSWPCGIG---ITTTICPTAVCTSKC

T SSWPC IG I+ +CPT CTSKC

TTSSWPCVIGAVDISANLCPTTKCTSKC

41.9%

NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

TTPSSWPCGIGITTTICPTAVCTSKC

TTP++ P + ++ ICPT CTSKC

TTPAT-PTIVAVSLGICPTTKCTSKC

41.9%

NZ_LT985747.1and 1 other:

NZ_LT985747.1 Lanthipeptides: C8268_RS00150_lanthipeptide

Lanthipeptides: C8268_RS00150_lanthipeptide

GTTPSSWPCGIGITTTICPTAVCTSKC

G T SSW CG +T +CP+ CT C

GITTSSWICGF-VTAALCPSTACTGDC

41.4%

NZ_CP040938.1and 1 other:

NZ_CP040938.1 Lanthipeptides: B5772_RS02455_lanthipeptide

Lanthipeptides: B5772_RS02455_lanthipeptide

SSWPCGIGITTTICPTAVCTSKC

+S PC + +T ICPT VC++KC

TSIPCAVMASTAICPTLVCSNKC

40.6%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

TTPSSWPCGIGITTTICPTAVCTSKC

TTP++ +GI+ +CPT CTSKC

TTPATPTIVVGISVGLCPTTKCTSKC

MIBiG 4.0 matches for E4J16_RS14990

28.6%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

ICPTAVCTSKC

CPT CTSKC

FCPTTKCTSKC

21.6%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

IGITTTICPTAVCTSKC

+G++ CPT CTS+C

VGVSAAFCPTTKCTSRC

allorf_0075864_0076013

Leader:

MAGVRGCARRRRGAAAAGA

Core:

VASWGCGWANCRGALNRPSRACSMVCVSPD

Core with dehydrations:

VADhaWGCysGWANCysRGALNRPDhaRACysDhaMVCysVDhaPD

antiSMASH-DB 4.0 matches for allorf_0075864_0076013

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0075864_0076013_lanthipeptide

Lanthipeptides: allorf_0075864_0076013_lanthipeptide

VASWGCGWANCRGALNRPSRACSMVCVSPD

30.3%

NC_015215.1and 5 others:

NC_015215.1 Lanthipeptides: SGGBAA2069_RS00700_lanthipeptideNZ_JAKUYO010000004.1 Lanthipeptides: MK556_RS09790_lanthipeptideNZ_JAKUYO010000004.1 Lanthipeptides: MK556_RS09790_lanthipeptideNZ_JAMDHZ010000003.1 Lanthipeptides: M5Q10_RS05355_lanthipeptideNZ_JAMDHZ010000003.1 Lanthipeptides: M5Q10_RS05355_lanthipeptide

Lanthipeptides: SGGBAA2069_RS00700_lanthipeptide

GCGWA-----NCRGALNRPSRACSMVCVSP

GC WA + AL + + AC+ C P

GCAWAAVSAISTVSALFQITTACTTRCYHP

27.3%

NZ_QORY01000016.1and 1 other:

NZ_QORY01000016.1 Lanthipeptides: DT250_RS18265_lanthipeptide

Lanthipeptides: DT250_RS18265_lanthipeptide

SWGCGWANCRGALNRPSRACSMVCV

+WGC A P+ ACS C+

TWGCAIFTIASAAQCPTTACSSKCL

with 1 more sequence matches

17.6%

NZ_KB913037.1:

Lanthipeptides: allorf_10324079_10324312_lanthipeptide

GWANCRGALN

GW+ CRGA+

GWSGCRGAIG

MIBiG 4.0 matches for allorf_0075864_0076013

16.7%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

CGWANCRGALNRPSRACSMV

C W N L C++

CAWYNISCRLGNKGAYCTLT

allorf_0076232_0076441

Leader:

MRGLQAEPARPPGPRGRAWGRASRPRPSVVMRRFVFGG

Core:

VGGAGRWFVGVLCADLVCSPVRGLLRRFGVC

Core with dehydrations:

VGGAGRWFVGVLCysADLVCysDhaPVRGLLRRFGVCys

antiSMASH-DB 4.0 matches for allorf_0076232_0076441

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0076232_0076441_lanthipeptide

Lanthipeptides: allorf_0076232_0076441_lanthipeptide

VGGAGRWFVGVLCADLVCSPVRGLLRRFGVC

25.8%

NZ_CP077072.1:

Lanthipeptides: allorf_4755020_4755199_lanthipeptide

GAGRWFVGVLCADLVCSPVRG

G G W G+ C P+RG

GCGPWRSGLRCPSGKEEPLRG

19.2%

NZ_CP014326.1:

Lanthipeptides: AXK38_RS05515_lanthipeptide

GAGRWFVGVLCADLVCSPVRGLLRRF

GAG W G+L A C+ + G+ R

GAGTWAGGILGAQY-CTAIWGIARSL

with 2 more sequence matches

14.0%

NZ_CP098485.1:

Lanthipeptides: allorf_6386875_6387051_lanthipeptide

GGAGRWFVGVLCADL

G RW + LCA L

GAHSRWIIHFLCAAL

12.5%

NZ_KB899666.1:

Lanthipeptides: allorf_268670_268867_lanthipeptide

CSPVRGLLR

C+PVRG +R

CTPVRGEIR

MIBiG 4.0 matches for allorf_0076232_0076441

12.9%

BGC0002322.3 (CEJ66604.1):

Lasso peptide: citrocin

GGAGRW

GG GR+

GGVGRY

9.7%

BGC0000563.4 (AEA03263.1):

Lanthipeptide: venezuelin

VGVLCA

+G+ CA

IGISCA

allorf_0076338_0076511

Leader:

MGVWVEPGGGSSACFALTSSARRFAVYYA

Core:

GSVSAEGSGRVSDCLCKGCGPTYKETRG

Core with dehydrations:

GDhaVDhaAEGDhaGRVDhaDCysLCysKGCysGPDhbYKEDhbRG

antiSMASH-DB 4.0 matches for allorf_0076338_0076511

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0076338_0076511_lanthipeptide

Lanthipeptides: allorf_0076338_0076511_lanthipeptide

GSVSAEGSGRVSDCLCKGCGPTYKETRG

25.8%

NZ_CP023694.1:

Lanthipeptides: CP976_RS43015_lanthipeptide

VSAEGSGRVSDCLCKGC

VSA+ ++ C CKGC

VSAKKCTKIKTCTCKGC

19.5%

NZ_JALGRP010000007.1and 1 other:

NZ_JALGRP010000007.1 Lanthipeptides: allorf_190248_190481_lanthipeptide

Lanthipeptides: allorf_190248_190481_lanthipeptide

EGSGRVSDCLCKGCGPTYKET

+G V+D C+ CGP +K +

KGQTDVADRRCRRCGPQWKRS

with 3 more sequence matches

17.9%

NZ_BDFA01000012.1and 5 others:

NZ_CP025018.1 Lanthipeptides: allorf_10559500_10559625_lanthipeptideNZ_CP029823.1 Lanthipeptides: allorf_10618379_10618504_lanthipeptideNZ_CP065050.1 Lanthipeptides: allorf_00914926_00915051_lanthipeptideNZ_JAALLH010000001.1 Lanthipeptides: allorf_0868535_0868660_lanthipeptideNZ_LJIW01000001.1 Lanthipeptides: allorf_0970869_0970994_lanthipeptide

Lanthipeptides: allorf_122369_122494_lanthipeptide

EGSGRVSDCLCKGCGPTYK

+GR +C + P Y+

HATGRFHECAVEQLPPLYR

17.9%

NZ_CP019458.1:

Lanthipeptides: allorf_00977826_00977951_lanthipeptide

EGSGRVSDCLCKGCGPTYK

+GR +C + P Y+

HATGRFHECTVEQLPPLYR

17.9%

NZ_WIXN01000006.1:

Lanthipeptides: allorf_110297_110410_lanthipeptide

GRVSDCLCKGCGPTY

+ DC+ CG Y

AHLIDCIWNACGIYY

allorf_0079268_0079333

Leader:

MKSCGSVDRVPGA

Core:

SRRKWCNL

Core with dehydrations:

DhaRRKWCysNL

antiSMASH-DB 4.0 matches for allorf_0079268_0079333

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0079268_0079333_lanthipeptide

Lanthipeptides: allorf_0079268_0079333_lanthipeptide

SRRKWCNL

allorf_0079275_0079346

Leader:

MHHFRRDAPGT

Core:

RSTEPHDFNDLC

Core with dehydrations:

RDhaDhbEPHDFNDLCys

antiSMASH-DB 4.0 matches for allorf_0079275_0079346

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0079275_0079346_lanthipeptide

Lanthipeptides: allorf_0079275_0079346_lanthipeptide

RSTEPHDFNDLC

11.5%

NZ_CP011129.1and 1 other:

NZ_CP013141.1 Lanthipeptides: allorf_5335460_5335672_lanthipeptide

Lanthipeptides: allorf_3828668_3828880_lanthipeptide

RSTEPHD

R+TEPHD

RTTEPHD

allorf_0079649_0079816

Leader:

MSVPFGSGVSGA

Core:

DAVGSPPVVVADRDKCVRRPGCFPSAERLRLMRLKEEPGPTIV

Core with dehydrations:

DAVGDhaPPVVVADRDKCysVRRPGCysFPDhaAERLRLMRLKEEPGPDhbIV

antiSMASH-DB 4.0 matches for allorf_0079649_0079816

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0079649_0079816_lanthipeptide

Lanthipeptides: allorf_0079649_0079816_lanthipeptide

DAVGSPPVVVADRDKCVRRPGCFPSAERLRLMRLKEEPGPTIV

23.3%

NZ_CP077072.1:

Lanthipeptides: allorf_4755020_4755199_lanthipeptide

VRRPGCFPSAERLRLMRLKEEP

R GC P LR KEEP

ARGDGCGPWRSGLRCPSGKEEP

16.7%

NZ_GL985606.1:

Lanthipeptides: allorf_0159575_0159772_lanthipeptide

VVVADRDKCVRR--PGCFPSAER

+ +R K RR PG P+A R

IATTNRSKAARRIRPGSPPTASR

with 4 more sequence matches

16.3%

NZ_CABJAL010000004.1:

Lanthipeptides: allorf_113329_113490_lanthipeptide

CVRRPGCFPSAERLRLMRLK

C+ CF S E L L+

CINATQCFNSTENLNTFYLQ

14.0%

NZ_FNCC01000010.1:

Lanthipeptides: allorf_129310_129399_lanthipeptide

CVRRPGCFPSAERLRLM

CV P C SA ++ +

CVMHPSCGVSAHSVKWV

14.0%

NZ_LACR01000015.1:

Lanthipeptides: allorf_040936_041022_lanthipeptide

RDKCVRRPGC

R++C RR GC

RNQCHRRYGC

11.3%

NZ_QRZZ01000003.1and 2 others:

NZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03680_lanthipeptideNZ_QUKU01000006.1 Lanthipeptides: DXC27_RS05520_lanthipeptide

Lanthipeptides: DWV87_RS03215_lanthipeptide

CVRRPGCFPSAERLR

V GC+P+A+R++

AVAMSGCYPNAQRIK

allorf_0090688_0090780

Leader:

MVMMNWSPGA

Core:

SREAACSWSQPCGQRGGPGR

Core with dehydrations:

DhaREAACysDhaWDhaQPCysGQRGGPGR

antiSMASH-DB 4.0 matches for allorf_0090688_0090780

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0090688_0090780_lanthipeptide

Lanthipeptides: allorf_0090688_0090780_lanthipeptide

SREAACSWSQPCGQRGGPGR

28.6%

NC_017765.1and 2 others:

NZ_CP013219.1 Lanthipeptides: allorf_0171989_0172081_lanthipeptideNZ_KQ948355.1 Lanthipeptides: allorf_085143_085235_lanthipeptide

Lanthipeptides: allorf_01990982_01991074_lanthipeptide

SQPCGQRGG

+ PCG RGG

TSPCGGRGG

23.1%

NZ_BORO01000007.1and 5 others:

NZ_JALASB010000016.1 Lanthipeptides: MOD42_RS18070_lanthipeptideNZ_JALASR010000012.1 Lanthipeptides: MOD87_RS16305_lanthipeptideNZ_JALAUW010000005.1 Lanthipeptides: MOE83_RS03160_lanthipeptideNZ_JALAXQ010000010.1 Lanthipeptides: MOF24_RS12150_lanthipeptideNZ_KZ454939.1 Lanthipeptides: CEF20_RS01155_lanthipeptide

Lanthipeptides: KI343_RS07745_lanthipeptide

SREAACSWSQP

EAAC+W+ P

DMEAACTWTLP

with 4 more sequence matches

19.2%

NC_017912.1and 14 others:

NZ_CP007242.1 Lanthipeptides: KHU1_RS17410_lanthipeptideNZ_CP031424.1 Lanthipeptides: DXX91_RS18935_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS10440_lanthipeptideNZ_CP043809.1 Lanthipeptides: ETZ92_RS14260_lanthipeptideNZ_CP049904.1 Lanthipeptides: V753_RS18470_lanthipeptideNZ_CP053764.1 Lanthipeptides: HPQ66_RS18325_lanthipeptideNZ_CP061938.1 Lanthipeptides: IEN91_RS19800_lanthipeptideNZ_CP063768.1 Lanthipeptides: IM712_RS05205_lanthipeptideNZ_CP087137.1 Lanthipeptides: LOK79_RS18580_lanthipeptideNZ_CP092383.1 Lanthipeptides: MID02_RS19390_lanthipeptideNZ_JAEACM010000001.1 Lanthipeptides: I5F15_RS04355_lanthipeptideNZ_JAJNPN010000015.1 Lanthipeptides: LQ568_RS13285_lanthipeptideNZ_SDKF01000002.1 Lanthipeptides: EUA41_RS09950_lanthipeptideNZ_VDUT01000007.1 Lanthipeptides: FS412_RS14545_lanthipeptide

Lanthipeptides: MUS_RS20065_lanthipeptide

SREAACSWSQP

EAAC+++ P

DMEAACTFTLP

17.9%

NZ_CP025546.1and 5 others:

NZ_CP025546.1 Lanthipeptides: allorf_4260056_4260220_lanthipeptideNZ_SDLM01000003.1 Lanthipeptides: allorf_121827_121991_lanthipeptideNZ_SDLM01000003.1 Lanthipeptides: allorf_121827_121991_lanthipeptideNZ_SDLN01000007.1 Lanthipeptides: allorf_135103_135267_lanthipeptideNZ_SDLN01000007.1 Lanthipeptides: allorf_135103_135267_lanthipeptide

Lanthipeptides: allorf_4260056_4260220_lanthipeptide

WSQPCGQRGGP

W+ PC G P

WATPCSLNGNP

13.5%

NZ_LILB01000005.1:

Lanthipeptides: AMD00_RS23330_lanthipeptide

SREAACSWSQPC

+++A CS+ PC

TKQAGCSFIPPC

13.0%

NZ_CP046122.1:

Lanthipeptides: allorf_1397846_1398043_lanthipeptide

AACSWSQPCGQRGG

+AC +QP G+R G

SACVANQPRGKRSG

allorf_0091131_0091220

Leader:

MGRRQGMASGG

Core:

GRFVCLPDGSSGSSNSSA

Core with dehydrations:

GRFVCysLPDGDhaDhaGDhaDhaNDhaDhaA

antiSMASH-DB 4.0 matches for allorf_0091131_0091220

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0091131_0091220_lanthipeptide

Lanthipeptides: allorf_0091131_0091220_lanthipeptide

GRFVCLPDGSSGSSNSSA

26.3%

NZ_AUBN01000022.1:

Lanthipeptides: allorf_02867_02956_lanthipeptide

VCLPDGSSGSSNS

VC P G G +++

VCFPSGPVGPAHT

Lanthipeptide(s) for E4J16_RS00340

E4J16_RS14990

Leader:

MTHENLTGTYTASELEELNDISAYG

Core:

GTTPSSWPCGIGITTTICPTAVCTSKCR

Core with dehydrations:

GDhbDhbPDhaDhaWPCysGIGIDhbDhbDhbICysPDhbAVCysDhbDhaKCysR

antiSMASH-DB 4.0 matches for E4J16_RS14990

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: E4J16_RS14990_lanthipeptide

Lanthipeptides: E4J16_RS14990_lanthipeptide

GTTPSSWPCGIGITTTICPTAVCTSKCR

89.3%

NZ_CP025249.1and 1 other:

NZ_CP025249.1 Lanthipeptides: CWT12_RS00390_lanthipeptide

Lanthipeptides: CWT12_RS00390_lanthipeptide

GTTPSSWPCGIGITTTICPTAVCTSKCR

GTTPSSWPCGIGITTT+CPTA C+SKCR

GTTPSSWPCGIGITTTVCPTAACSSKCR

50.0%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS18310_lanthipeptide

SSWPCGIGITTTI----CPTAVCTSKC

++ PC +GIT TI CPT CTS+C

TTLPC-VGITVTISVSMCPTTKCTSQC

with 81 more sequence matches

Only the first 10 are displayed here.

46.9%

NC_021362.1and 29 others:

Lanthipeptides: BALI_RS00915_lanthipeptide

TTPSSWPCGIGITTTICPTAVCTSKC

TTPSS PCG +T CP+ CTS C

TTPSSLPCGTLVTAVWCPSNACTSDC

46.9%

NZ_CP006058.1and 25 others:

Lanthipeptides: BAMY6639_RS19790_lanthipeptide

TTPSSWPCGIGITTTICPTAVCTSKC

TTPSS PCG+ +T CP+ CTS C

TTPSSLPCGVFVTAAFCPSTKCTSSC

46.9%

NZ_CP013862.1and 1 other:

NZ_CP013862.1 Lanthipeptides: AOX59_RS09365_lanthipeptide

Lanthipeptides: AOX59_RS09365_lanthipeptide

TTPSSWPCGIGITTTICPTAVCTSKC

TTPSS CGI ++ CPT CTS+C

TTPSSVACGIAVSALFCPTTKCTSQC

46.4%

NZ_CP084530.1and 1 other:

NZ_CP084530.1 Lanthipeptides: LDO05_RS02090_lanthipeptide

Lanthipeptides: LDO05_RS02090_lanthipeptide

TPSSWPCGIGITTTICPTAVCTSKC

T SSW CG+ + CP+ CTSKC

TTSSWICGVA-SAAFCPSTACTSKC

45.5%

NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21840_lanthipeptide

Lanthipeptides: CN325_RS21840_lanthipeptide

TPSSWPCGIGITTTI----CPTAVCTSKC

T ++ PCGIG T TI CPT+ CT +C

TSTTVPCGIGSTITISIAYCPTSKCTERC

43.6%

NZ_CP009280.1and 1 other:

NZ_CP009280.1 Lanthipeptides: P40081_RS37160_lanthipeptide

Lanthipeptides: P40081_RS37160_lanthipeptide

TPSSWPCGIG---ITTTICPTAVCTSKC

T SSWPC IG I+ +CPT CTSKC

TTSSWPCVIGAVDISANLCPTTKCTSKC

41.9%

NC_018499.1and 5 others:

Lanthipeptides: BCK_RS27845_lanthipeptide

TTPSSWPCGIGITTTICPTAVCTSKC

TTP++ P + ++ ICPT CTSKC

TTPAT-PTIVAVSLGICPTTKCTSKC

41.9%

NZ_LT985747.1and 1 other:

NZ_LT985747.1 Lanthipeptides: C8268_RS00150_lanthipeptide

Lanthipeptides: C8268_RS00150_lanthipeptide

GTTPSSWPCGIGITTTICPTAVCTSKC

G T SSW CG +T +CP+ CT C

GITTSSWICGF-VTAALCPSTACTGDC

41.4%

NZ_CP040938.1and 1 other:

NZ_CP040938.1 Lanthipeptides: B5772_RS02455_lanthipeptide

Lanthipeptides: B5772_RS02455_lanthipeptide

SSWPCGIGITTTICPTAVCTSKC

+S PC + +T ICPT VC++KC

TSIPCAVMASTAICPTLVCSNKC

40.6%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

TTPSSWPCGIGITTTICPTAVCTSKC

TTP++ +GI+ +CPT CTSKC

TTPATPTIVVGISVGLCPTTKCTSKC

MIBiG 4.0 matches for E4J16_RS14990

28.6%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

ICPTAVCTSKC

CPT CTSKC

FCPTTKCTSKC

21.6%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

IGITTTICPTAVCTSKC

+G++ CPT CTS+C

VGVSAAFCPTTKCTSRC

allorf_0075864_0076013

Leader:

MAGVRGCARRRRGAAAAGA

Core:

VASWGCGWANCRGALNRPSRACSMVCVSPD

Core with dehydrations:

VADhaWGCysGWANCysRGALNRPDhaRACysDhaMVCysVDhaPD

antiSMASH-DB 4.0 matches for allorf_0075864_0076013

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0075864_0076013_lanthipeptide

Lanthipeptides: allorf_0075864_0076013_lanthipeptide

VASWGCGWANCRGALNRPSRACSMVCVSPD

30.3%

NC_015215.1and 5 others:

Lanthipeptides: SGGBAA2069_RS00700_lanthipeptide

GCGWA-----NCRGALNRPSRACSMVCVSP

GC WA + AL + + AC+ C P

GCAWAAVSAISTVSALFQITTACTTRCYHP

27.3%

NZ_QORY01000016.1and 1 other:

NZ_QORY01000016.1 Lanthipeptides: DT250_RS18265_lanthipeptide

Lanthipeptides: DT250_RS18265_lanthipeptide

SWGCGWANCRGALNRPSRACSMVCV

+WGC A P+ ACS C+

TWGCAIFTIASAAQCPTTACSSKCL

with 1 more sequence matches

17.6%

NZ_KB913037.1:

Lanthipeptides: allorf_10324079_10324312_lanthipeptide

GWANCRGALN

GW+ CRGA+

GWSGCRGAIG

MIBiG 4.0 matches for allorf_0075864_0076013

16.7%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

CGWANCRGALNRPSRACSMV

C W N L C++

CAWYNISCRLGNKGAYCTLT

allorf_0076232_0076441

Leader:

MRGLQAEPARPPGPRGRAWGRASRPRPSVVMRRFVFGG

Core:

VGGAGRWFVGVLCADLVCSPVRGLLRRFGVC

Core with dehydrations:

VGGAGRWFVGVLCysADLVCysDhaPVRGLLRRFGVCys

antiSMASH-DB 4.0 matches for allorf_0076232_0076441

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0076232_0076441_lanthipeptide

Lanthipeptides: allorf_0076232_0076441_lanthipeptide

VGGAGRWFVGVLCADLVCSPVRGLLRRFGVC

25.8%

NZ_CP077072.1:

Lanthipeptides: allorf_4755020_4755199_lanthipeptide

GAGRWFVGVLCADLVCSPVRG

G G W G+ C P+RG

GCGPWRSGLRCPSGKEEPLRG

19.2%

NZ_CP014326.1:

Lanthipeptides: AXK38_RS05515_lanthipeptide

GAGRWFVGVLCADLVCSPVRGLLRRF

GAG W G+L A C+ + G+ R

GAGTWAGGILGAQY-CTAIWGIARSL

with 2 more sequence matches

14.0%

NZ_CP098485.1:

Lanthipeptides: allorf_6386875_6387051_lanthipeptide

GGAGRWFVGVLCADL

G RW + LCA L

GAHSRWIIHFLCAAL

12.5%

NZ_KB899666.1:

Lanthipeptides: allorf_268670_268867_lanthipeptide

CSPVRGLLR

C+PVRG +R

CTPVRGEIR

MIBiG 4.0 matches for allorf_0076232_0076441

12.9%

BGC0002322.3 (CEJ66604.1):

Lasso peptide: citrocin

GGAGRW

GG GR+

GGVGRY

9.7%

BGC0000563.4 (AEA03263.1):

Lanthipeptide: venezuelin

VGVLCA

+G+ CA

IGISCA

allorf_0076338_0076511

Leader:

MGVWVEPGGGSSACFALTSSARRFAVYYA

Core:

GSVSAEGSGRVSDCLCKGCGPTYKETRG

Core with dehydrations:

GDhaVDhaAEGDhaGRVDhaDCysLCysKGCysGPDhbYKEDhbRG

antiSMASH-DB 4.0 matches for allorf_0076338_0076511

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0076338_0076511_lanthipeptide

Lanthipeptides: allorf_0076338_0076511_lanthipeptide

GSVSAEGSGRVSDCLCKGCGPTYKETRG

25.8%

NZ_CP023694.1:

Lanthipeptides: CP976_RS43015_lanthipeptide

VSAEGSGRVSDCLCKGC

VSA+ ++ C CKGC

VSAKKCTKIKTCTCKGC

19.5%

NZ_JALGRP010000007.1and 1 other:

NZ_JALGRP010000007.1 Lanthipeptides: allorf_190248_190481_lanthipeptide

Lanthipeptides: allorf_190248_190481_lanthipeptide

EGSGRVSDCLCKGCGPTYKET

+G V+D C+ CGP +K +

KGQTDVADRRCRRCGPQWKRS

with 3 more sequence matches

17.9%

NZ_BDFA01000012.1and 5 others:

Lanthipeptides: allorf_122369_122494_lanthipeptide

EGSGRVSDCLCKGCGPTYK

+GR +C + P Y+

HATGRFHECAVEQLPPLYR

17.9%

NZ_CP019458.1:

Lanthipeptides: allorf_00977826_00977951_lanthipeptide

EGSGRVSDCLCKGCGPTYK

+GR +C + P Y+

HATGRFHECTVEQLPPLYR

17.9%

NZ_WIXN01000006.1:

Lanthipeptides: allorf_110297_110410_lanthipeptide

GRVSDCLCKGCGPTY

+ DC+ CG Y

AHLIDCIWNACGIYY

allorf_0079268_0079333

Leader:

MKSCGSVDRVPGA

Core:

SRRKWCNL

Core with dehydrations:

DhaRRKWCysNL

antiSMASH-DB 4.0 matches for allorf_0079268_0079333

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0079268_0079333_lanthipeptide

Lanthipeptides: allorf_0079268_0079333_lanthipeptide

SRRKWCNL

allorf_0079275_0079346

Leader:

MHHFRRDAPGT

Core:

RSTEPHDFNDLC

Core with dehydrations:

RDhaDhbEPHDFNDLCys

antiSMASH-DB 4.0 matches for allorf_0079275_0079346

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0079275_0079346_lanthipeptide

Lanthipeptides: allorf_0079275_0079346_lanthipeptide

RSTEPHDFNDLC

11.5%

NZ_CP011129.1and 1 other:

NZ_CP013141.1 Lanthipeptides: allorf_5335460_5335672_lanthipeptide

Lanthipeptides: allorf_3828668_3828880_lanthipeptide

RSTEPHD

R+TEPHD

RTTEPHD

allorf_0079649_0079816

Leader:

MSVPFGSGVSGA

Core:

DAVGSPPVVVADRDKCVRRPGCFPSAERLRLMRLKEEPGPTIV

Core with dehydrations:

DAVGDhaPPVVVADRDKCysVRRPGCysFPDhaAERLRLMRLKEEPGPDhbIV

antiSMASH-DB 4.0 matches for allorf_0079649_0079816

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0079649_0079816_lanthipeptide

Lanthipeptides: allorf_0079649_0079816_lanthipeptide

DAVGSPPVVVADRDKCVRRPGCFPSAERLRLMRLKEEPGPTIV

23.3%

NZ_CP077072.1:

Lanthipeptides: allorf_4755020_4755199_lanthipeptide

VRRPGCFPSAERLRLMRLKEEP

R GC P LR KEEP

ARGDGCGPWRSGLRCPSGKEEP

16.7%

NZ_GL985606.1:

Lanthipeptides: allorf_0159575_0159772_lanthipeptide

VVVADRDKCVRR--PGCFPSAER

+ +R K RR PG P+A R

IATTNRSKAARRIRPGSPPTASR

with 4 more sequence matches

16.3%

NZ_CABJAL010000004.1:

Lanthipeptides: allorf_113329_113490_lanthipeptide

CVRRPGCFPSAERLRLMRLK

C+ CF S E L L+

CINATQCFNSTENLNTFYLQ

14.0%

NZ_FNCC01000010.1:

Lanthipeptides: allorf_129310_129399_lanthipeptide

CVRRPGCFPSAERLRLM

CV P C SA ++ +

CVMHPSCGVSAHSVKWV

14.0%

NZ_LACR01000015.1:

Lanthipeptides: allorf_040936_041022_lanthipeptide

RDKCVRRPGC

R++C RR GC

RNQCHRRYGC

11.3%

NZ_QRZZ01000003.1and 2 others:

NZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03680_lanthipeptideNZ_QUKU01000006.1 Lanthipeptides: DXC27_RS05520_lanthipeptide

Lanthipeptides: DWV87_RS03215_lanthipeptide

CVRRPGCFPSAERLR

V GC+P+A+R++

AVAMSGCYPNAQRIK

allorf_0090688_0090780

Leader:

MVMMNWSPGA

Core:

SREAACSWSQPCGQRGGPGR

Core with dehydrations:

DhaREAACysDhaWDhaQPCysGQRGGPGR

antiSMASH-DB 4.0 matches for allorf_0090688_0090780

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0090688_0090780_lanthipeptide

Lanthipeptides: allorf_0090688_0090780_lanthipeptide

SREAACSWSQPCGQRGGPGR

28.6%

NC_017765.1and 2 others:

NZ_CP013219.1 Lanthipeptides: allorf_0171989_0172081_lanthipeptideNZ_KQ948355.1 Lanthipeptides: allorf_085143_085235_lanthipeptide

Lanthipeptides: allorf_01990982_01991074_lanthipeptide

SQPCGQRGG

+ PCG RGG

TSPCGGRGG

23.1%

NZ_BORO01000007.1and 5 others:

Lanthipeptides: KI343_RS07745_lanthipeptide

SREAACSWSQP

EAAC+W+ P

DMEAACTWTLP

with 4 more sequence matches

19.2%

NC_017912.1and 14 others:

Lanthipeptides: MUS_RS20065_lanthipeptide

SREAACSWSQP

EAAC+++ P

DMEAACTFTLP

17.9%

NZ_CP025546.1and 5 others:

Lanthipeptides: allorf_4260056_4260220_lanthipeptide

WSQPCGQRGGP

W+ PC G P

WATPCSLNGNP

13.5%

NZ_LILB01000005.1:

Lanthipeptides: AMD00_RS23330_lanthipeptide

SREAACSWSQPC

+++A CS+ PC

TKQAGCSFIPPC

13.0%

NZ_CP046122.1:

Lanthipeptides: allorf_1397846_1398043_lanthipeptide

AACSWSQPCGQRGG

+AC +QP G+R G

SACVANQPRGKRSG

allorf_0091131_0091220

Leader:

MGRRQGMASGG

Core:

GRFVCLPDGSSGSSNSSA

Core with dehydrations:

GRFVCysLPDGDhaDhaGDhaDhaNDhaDhaA

antiSMASH-DB 4.0 matches for allorf_0091131_0091220

100.0%

NZ_CP039292.1and 1 other:

NZ_CP039292.1 Lanthipeptides: allorf_0091131_0091220_lanthipeptide

Lanthipeptides: allorf_0091131_0091220_lanthipeptide

GRFVCLPDGSSGSSNSSA

26.3%

NZ_AUBN01000022.1:

Lanthipeptides: allorf_02867_02956_lanthipeptide

VCLPDGSSGSSNS

VC P G G +++

VCFPSGPVGPAHT

allorf_0094300_0094539

Leader:

MVLGLGDGCHSQAPKPSPVRRSNPEALCPHARCRRKGGCQRVRWSRPPGQTPFCPAGRACYSRPRGADSASA

Core:

LCSSSVR

Core with dehydrations:

LCysDhaDhaDhaVR

antiSMASH-DB 4.0 matches for allorf_0094300_0094539

100.0%

NZ_CP039292.1:

Lanthipeptides: allorf_0094300_0094539_lanthipeptide

LCSSSVR

allorf_0094578_0094799

Leader:

MRHIQFGYVNDAGEIRANDSLGEAVTWMGDGGSAGA

Core:

AAAGVVSPRSDTDMAMAERVRRERMCEDFLTVVDPVG

Core with dehydrations:

AAAGVVDhaPRDhaDDhbDMAMAERVRRERMCysEDFLDhbVVDPVG

antiSMASH-DB 4.0 matches for allorf_0094578_0094799

100.0%

NZ_CP039292.1:

Lanthipeptides: allorf_0094578_0094799_lanthipeptide

AAAGVVSPRSDTDMAMAERVRRERMCEDFLTVVDPVG

45.5%

NZ_CP025249.1and 1 other:

NZ_CP025249.1 Lanthipeptides: allorf_0098372_0098596_lanthipeptide

Lanthipeptides: allorf_0098372_0098596_lanthipeptide

AAAGVVSPRSDTDMAMAERVRRERMCEDFLTVVDPVG

A G+ SPRSDTDMAMAERVRRE MC DFL+VVDPVG

ATEGLASPRSDTDMAMAERVRREHMCGDFLSVVDPVG

allorf_0094630_0094776

Leader:

MIRSVRRLHGWEMGVRRVLLRRELSAPGA

Core:

IRTWRWQRGCEGNACARTS

Core with dehydrations:

IRDhbWRWQRGCysEGNACysARDhbDha

antiSMASH-DB 4.0 matches for allorf_0094630_0094776

100.0%

NZ_CP039292.1:

Lanthipeptides: allorf_0094630_0094776_lanthipeptide

IRTWRWQRGCEGNACARTS

39.0%

NZ_CP025249.1and 1 other:

NZ_CP025249.1 Lanthipeptides: allorf_0098430_0098639_lanthipeptide

Lanthipeptides: allorf_0098430_0098639_lanthipeptide

IRTWRWQRGCEGNACARTS

I+TWRWQRGCEGN CA TS

IQTWRWQRGCEGNTCAVTS

31.6%

NZ_CP031746.1:

Lanthipeptides: allorf_1813942_1814025_lanthipeptide

IRTWRWQRGCEG

+RT W+ GC G

LRTVAWRPGCPG

with 3 more sequence matches

31.6%

NZ_LMGK01000023.1and 1 other:

NZ_RCNY01000084.1 Lanthipeptides: allorf_084168_084254_lanthipeptide

Lanthipeptides: allorf_096724_096810_lanthipeptide

EGNACA

22.2%

NZ_CP054919.1and 1 other:

NZ_CP054919.1 Lanthipeptides: HUT16_RS27255_lanthipeptide

Lanthipeptides: HUT16_RS27255_lanthipeptide

CEGNACA

CEG+ACA

CEGSACA

15.4%

NZ_LR134504.1:

Lanthipeptides: allorf_1619680_1619865_lanthipeptide

WRWQRGCEGNAC

RW + C G+AC

LRWAKSCLGSAC

MIBiG 4.0 matches for allorf_0094630_0094776

18.2%

BGC0000563.4 (AEA03263.1):

Lanthipeptide: venezuelin

CEGNACA

C G +CA

CIGISCA

allorf_0097938_0098072

Leader:

MTHATSKHRLHNTFLSRRSFGQSEDAIAG

Core:

IRECSGFPPRPVLPW

Core with dehydrations:

IRECysDhaGFPPRPVLPW

antiSMASH-DB 4.0 matches for allorf_0097938_0098072

100.0%

NZ_CP039292.1:

Lanthipeptides: allorf_0097938_0098072_lanthipeptide

IRECSGFPPRPVLPW

15.4%

NZ_BMJA01000007.1:

Lanthipeptides: allorf_022673_022864_lanthipeptide

RECSGFPPRP

R C+GF P P

RVCTGFRPSP

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (5):

HipB

Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 19.59 out of 33.73

Confidence: weak

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 19.18 out of 30.25

Confidence: weak

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 15.27 out of 18.57

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 22.76 out of 32.74

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 22.63 out of 32.74

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

E4J16_RS14990 - Class II

Cleavage pHMM score: -6.30

RODEO score: 0

Monoisotopic mass: 2660.3 Da

Molecular weight: 2662.1 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 2680.1 Da N = 1; 2698.1 Da N = 2; 2716.2 Da N = 3; 2734.2 Da N = 4; 2752.2 Da N = 5; 2770.2 Da N = 6

allorf_0075864_0076013 - Class II

Cleavage pHMM score: -3.60

RODEO score: 0

Monoisotopic mass: 3080.4 Da

Molecular weight: 3082.5 Da

Number of bridges: 4

allorf_0076232_0076441 - Class II

Cleavage pHMM score: -5.60

RODEO score: 0

Monoisotopic mass: 3243.7 Da

Molecular weight: 3245.9 Da

Number of bridges: 1

allorf_0076338_0076511 - Class II

Cleavage pHMM score: -4.20

RODEO score: 0

Monoisotopic mass: 2695.3 Da

Molecular weight: 2697.0 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2715.0 Da N = 1; 2733.0 Da N = 2; 2751.0 Da N = 3

allorf_0079268_0079333 - Class II

Cleavage pHMM score: -4.10

RODEO score: 0

Monoisotopic mass: 1043.6 Da

Molecular weight: 1044.2 Da

Number of bridges: 1

allorf_0079275_0079346 - Class II

Cleavage pHMM score: -7.30

RODEO score: 0

Monoisotopic mass: 1396.6 Da

Molecular weight: 1397.5 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1415.5 Da N = 1

allorf_0079649_0079816 - Class II

Cleavage pHMM score: -4.80

RODEO score: 0

Monoisotopic mass: 4661.5 Da

Molecular weight: 4664.4 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 4682.4 Da N = 1

allorf_0090688_0090780 - Class II

Cleavage pHMM score: -6.30

RODEO score: 0

Monoisotopic mass: 2034.9 Da

Molecular weight: 2036.2 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 2054.2 Da N = 1

allorf_0091131_0091220 - Class II

Cleavage pHMM score: -5.90

RODEO score: 0

Monoisotopic mass: 1618.8 Da

Molecular weight: 1619.7 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1637.7 Da N = 1; 1655.7 Da N = 2; 1673.7 Da N = 3; 1691.8 Da N = 4; 1709.8 Da N = 5

E4J16_RS14990 - Class II

Cleavage pHMM score: -6.30

RODEO score: 0

Monoisotopic mass: 2660.3 Da

Molecular weight: 2662.1 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 2680.1 Da N = 1; 2698.1 Da N = 2; 2716.2 Da N = 3; 2734.2 Da N = 4; 2752.2 Da N = 5; 2770.2 Da N = 6

allorf_0075864_0076013 - Class II

Cleavage pHMM score: -3.60

RODEO score: 0

Monoisotopic mass: 3080.4 Da

Molecular weight: 3082.5 Da

Number of bridges: 4

allorf_0076232_0076441 - Class II

Cleavage pHMM score: -5.60

RODEO score: 0

Monoisotopic mass: 3243.7 Da

Molecular weight: 3245.9 Da

Number of bridges: 1

allorf_0076338_0076511 - Class II

Cleavage pHMM score: -4.20

RODEO score: 0

Monoisotopic mass: 2695.3 Da

Molecular weight: 2697.0 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2715.0 Da N = 1; 2733.0 Da N = 2; 2751.0 Da N = 3

allorf_0079268_0079333 - Class II

Cleavage pHMM score: -4.10

RODEO score: 0

Monoisotopic mass: 1043.6 Da

Molecular weight: 1044.2 Da

Number of bridges: 1

allorf_0079275_0079346 - Class II

Cleavage pHMM score: -7.30

RODEO score: 0

Monoisotopic mass: 1396.6 Da

Molecular weight: 1397.5 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1415.5 Da N = 1

allorf_0079649_0079816 - Class II

Cleavage pHMM score: -4.80

RODEO score: 0

Monoisotopic mass: 4661.5 Da

Molecular weight: 4664.4 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 4682.4 Da N = 1

allorf_0090688_0090780 - Class II

Cleavage pHMM score: -6.30

RODEO score: 0

Monoisotopic mass: 2034.9 Da

Molecular weight: 2036.2 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 2054.2 Da N = 1

allorf_0091131_0091220 - Class II

Cleavage pHMM score: -5.90

RODEO score: 0

Monoisotopic mass: 1618.8 Da

Molecular weight: 1619.7 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1637.7 Da N = 1; 1655.7 Da N = 2; 1673.7 Da N = 3; 1691.8 Da N = 4; 1709.8 Da N = 5

allorf_0094300_0094539 - Class II

Cleavage pHMM score: -6.20

RODEO score: 0

Monoisotopic mass: 696.4 Da

Molecular weight: 696.8 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 714.8 Da N = 1; 732.8 Da N = 2

allorf_0094578_0094799 - Class II

Cleavage pHMM score: -2.40

RODEO score: 0

Monoisotopic mass: 3963.9 Da

Molecular weight: 3966.5 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 3984.5 Da N = 1; 4002.5 Da N = 2; 4020.5 Da N = 3

allorf_0094630_0094776 - Class II

Cleavage pHMM score: -5.90

RODEO score: 0

Monoisotopic mass: 2196.1 Da

Molecular weight: 2197.5 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 2215.5 Da N = 1

allorf_0097938_0098072 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 1734.9 Da

Molecular weight: 1736.0 Da

Number of bridges: 1

TFBS definitions

Regulator	Description

NZ_CP039292.1 - Region 2 - terpene-precursor

Download region GenBank file

Download region SVG

Location: 1,838,244 - 1,859,425 nt. (total: 21,182 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: phosphorylase

E4J16_RS07405: thiamine-phosphate pyrophosphorylase

smcogs: SMCOG1280: thiamine-phosphate pyrophosphorylase

Ligases: synthetase

E4J16_RS07420: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000677.5	0.38	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0002309.2	0.37	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0001911.3	0.34	terpene	raimonol	Streptomyces anulatus
BGC0001456.3	0.34	terpene	isorenieratene	Streptomyces argillaceus
BGC0001910.4	0.33	terpene	cyslabdan A, cyslabdan B, cyslabdan C	Streptomyces cyslabdanicus
BGC0000665.5	0.33	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0001521.3	0.33	NRPS	auriculamide	Herpetosiphon aurantiacus DSM 785
BGC0002339.3	0.33	terpene	2-hydroxysorangiadenosine	Vitiosangium cumulatum
BGC0000936.5	0.32	other (other)	pyocyanine	Pseudomonas aeruginosa PAO1
BGC0000664.5	0.32	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000677.5	0.38	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0002309.2	0.37	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0001911.3	0.34	terpene	raimonol	Streptomyces anulatus
BGC0001456.3	0.34	terpene	isorenieratene	Streptomyces argillaceus
BGC0001910.4	0.33	terpene	cyslabdan A, cyslabdan B, cyslabdan C	Streptomyces cyslabdanicus
BGC0000665.5	0.33	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0001521.3	0.33	NRPS	auriculamide	Herpetosiphon aurantiacus DSM 785
BGC0002339.3	0.33	terpene	2-hydroxysorangiadenosine	Vitiosangium cumulatum
BGC0000936.5	0.32	other (other)	pyocyanine	Pseudomonas aeruginosa PAO1
BGC0000664.5	0.32	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor	FPP	C15	acyclic	PP
diterpene precursor	GGPP	C20	acyclic	PP
sesterterpene precursor	GFPP	C25	acyclic	PP
triterpene precursor	HPP	C30	acyclic	PP

Genes with terpene domains:

E4J16_RS07420: PT_FPPS_like

Domain 1 (48 - 392): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

Terpene

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate