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Overview
1.1
1.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP039292.1 (Actinomyces procaprae)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1 | lanthipeptide-class-ii | 70,303 | 98,115 |
Region 2 | terpene-precursor | 1,838,244 | 1,859,425 |

NZ_CP039292.1 - Region 1 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 70,303 - 98,115 nt. (total: 27,813 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
binding site
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
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Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
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Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Lyases: cyclase
E4J16_RS00330: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

E4J16_RS00340: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001229.4 |  | 0.64 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000517.4 |  | 0.60 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0002110.3 |  | 0.59 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0000520.5 |  | 0.55 | ribosomal | lacticin 3147 A1, lacticin 3147 A2 | Lactococcus lactis
BGC0000552.3 |  | 0.53 | ribosomal | SmbA, SmbB | Streptococcus mutans
BGC0000555.3 |  | 0.53 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0000528.5 |  | 0.52 | ribosomal | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001311.5 |  | 0.52 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0002005.2 |  | 0.51 | ribosomal | RaxX | Xanthomonas oryzae pv. oryzae
BGC0000590.5 |  | 0.51 | ribosomal | microcin N | Escherichia coli

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001229.4 |  | 0.64 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000517.4 |  | 0.60 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0002110.3 |  | 0.59 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0000520.5 |  | 0.55 | ribosomal | lacticin 3147 A1, lacticin 3147 A2 | Lactococcus lactis
BGC0000552.3 |  | 0.53 | ribosomal | SmbA, SmbB | Streptococcus mutans
BGC0000555.3 |  | 0.53 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0000528.5 |  | 0.52 | ribosomal | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001311.5 |  | 0.52 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0002005.2 |  | 0.51 | ribosomal | RaxX | Xanthomonas oryzae pv. oryzae
BGC0000590.5 |  | 0.51 | ribosomal | microcin N | Escherichia coli

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for E4J16_RS00330

E4J16_RS14990
Leader:
MTHENLTGTYTASELEELNDISAYG
Core:
G T T P S S W P C G I G I T T T I C P T A V C T S K C R
Core with dehydrations:
G Dhb Dhb P Dha Dha W P Cys G I G I Dhb Dhb Dhb I Cys P Dhb A V Cys Dhb Dha K Cys R

#### antiSMASH-DB 4.0 matches for E4J16_RS14990

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: E4J16_RS14990_lanthipeptide
Lanthipeptides: E4J16_RS14990_lanthipeptide
1
G T T P S S W P C G I G I T T T I C P T A V C T S K C R
28
G T T P S S W P C G I G I T T T I C P T A V C T S K C R
1
G T T P S S W P C G I G I T T T I C P T A V C T S K C R
28
89.3%
NZ_CP025249.1 and 1 other:
NZ_CP025249.1 Lanthipeptides: CWT12_RS00390_lanthipeptide
Lanthipeptides: CWT12_RS00390_lanthipeptide
1
G T T P S S W P C G I G I T T T I C P T A V C T S K C R
28
G T T P S S W P C G I G I T T T+C P T A C+S K C R
1
G T T P S S W P C G I G I T T T V C P T A A C S S K C R
28
50.0%
NZ_LT630004.1:
Lanthipeptides: BQ5796_RS18310_lanthipeptide
5
S S W P C G I G I T T T I----C P T A V C T S K C
27
++ P C +G I T T I C P T C T S+C
2
T T L P C-V G I T V T I S V S M C P T T K C T S Q C
27
with 81 more sequence matches
Only the first 10 are displayed here.
46.9%
NC_021362.1 and 29 others:
NC_021362.1 Lanthipeptides: BALI_RS00915_lanthipeptide NZ_AP025342.1 Lanthipeptides: L6430_RS07475_lanthipeptide NZ_AP025342.1 Lanthipeptides: L6430_RS07475_lanthipeptide NZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20090_lanthipeptide NZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20090_lanthipeptide NZ_CP010524.1 Lanthipeptides: SC10_RS00915_lanthipeptide NZ_CP010524.1 Lanthipeptides: SC10_RS00915_lanthipeptide NZ_CP020352.1 Lanthipeptides: BLMD_RS01010_lanthipeptide NZ_CP020352.1 Lanthipeptides: BLMD_RS01010_lanthipeptide NZ_CP023168.1 Lanthipeptides: CK945_RS01010_lanthipeptide NZ_CP023168.1 Lanthipeptides: CK945_RS01010_lanthipeptide NZ_CP118744.1 Lanthipeptides: PWG69_RS01010_lanthipeptide NZ_CP118744.1 Lanthipeptides: PWG69_RS01010_lanthipeptide NZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20270_lanthipeptide NZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20270_lanthipeptide NZ_KN125579.1 Lanthipeptides: DJ88_RS03665_lanthipeptide NZ_KN125579.1 Lanthipeptides: DJ88_RS03665_lanthipeptide NZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19045_lanthipeptide NZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19045_lanthipeptide NZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16135_lanthipeptide NZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16135_lanthipeptide NZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11925_lanthipeptide NZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11925_lanthipeptide NZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01510_lanthipeptide NZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01510_lanthipeptide NZ_NKBC01000001.1 Lanthipeptides: CE036_RS00070_lanthipeptide NZ_NKBC01000001.1 Lanthipeptides: CE036_RS00070_lanthipeptide NZ_QXII01000007.1 Lanthipeptides: D1791_RS21810_lanthipeptide NZ_QXII01000007.1 Lanthipeptides: D1791_RS21810_lanthipeptide
Lanthipeptides: BALI_RS00915_lanthipeptide
2
T T P S S W P C G I G I T T T I C P T A V C T S K C
27
T T P S S P C G +T C P+ C T S C
7
T T P S S L P C G T L V T A V W C P S N A C T S D C
32
46.9%
NZ_CP006058.1 and 25 others:
NZ_CP006058.1 Lanthipeptides: BAMY6639_RS19790_lanthipeptide NZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptide NZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptide NZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptide NZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptide NZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptide NZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptide NZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptide NZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptide NZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptide NZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptide NZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptide NZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptide NZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptide NZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptide NZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptide NZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptide NZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptide NZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptide NZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptide NZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptide NZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptide NZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptide
Lanthipeptides: BAMY6639_RS19790_lanthipeptide
2
T T P S S W P C G I G I T T T I C P T A V C T S K C
27
T T P S S P C G+ +T C P+ C T S C
7
T T P S S L P C G V F V T A A F C P S T K C T S S C
32
46.9%
NZ_CP013862.1 and 1 other:
NZ_CP013862.1 Lanthipeptides: AOX59_RS09365_lanthipeptide
Lanthipeptides: AOX59_RS09365_lanthipeptide
2
T T P S S W P C G I G I T T T I C P T A V C T S K C
27
T T P S S C G I ++ C P T C T S+C
7
T T P S S V A C G I A V S A L F C P T T K C T S Q C
32
46.4%
NZ_CP084530.1 and 1 other:
NZ_CP084530.1 Lanthipeptides: LDO05_RS02090_lanthipeptide
Lanthipeptides: LDO05_RS02090_lanthipeptide
3
T P S S W P C G I G I T T T I C P T A V C T S K C
27
T S S W C G+ + C P+ C T S K C
5
T T S S W I C G V A-S A A F C P S T A C T S K C
28
45.5%
NZ_NTSF01000026.1 and 1 other:
NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21840_lanthipeptide
Lanthipeptides: CN325_RS21840_lanthipeptide
3
T P S S W P C G I G I T T T I----C P T A V C T S K C
27
T ++ P C G I G T T I C P T+ C T +C
1
T S T T V P C G I G S T I T I S I A Y C P T S K C T E R C
29
43.6%
NZ_CP009280.1 and 1 other:
NZ_CP009280.1 Lanthipeptides: P40081_RS37160_lanthipeptide
Lanthipeptides: P40081_RS37160_lanthipeptide
3
T P S S W P C G I G---I T T T I C P T A V C T S K C
27
T S S W P C I G I+ +C P T C T S K C
12
T T S S W P C V I G A V D I S A N L C P T T K C T S K C
39
41.9%
NC_018499.1 and 5 others:
NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide
Lanthipeptides: BCK_RS27845_lanthipeptide
2
T T P S S W P C G I G I T T T I C P T A V C T S K C
27
T T P++ P + ++ I C P T C T S K C
7
T T P A T-P T I V A V S L G I C P T T K C T S K C
31
41.9%
NZ_LT985747.1 and 1 other:
NZ_LT985747.1 Lanthipeptides: C8268_RS00150_lanthipeptide
Lanthipeptides: C8268_RS00150_lanthipeptide
1
G T T P S S W P C G I G I T T T I C P T A V C T S K C
27
G T S S W C G +T +C P+ C T C
6
G I T T S S W I C G F-V T A A L C P S T A C T G D C
31
41.4%
NZ_CP040938.1 and 1 other:
NZ_CP040938.1 Lanthipeptides: B5772_RS02455_lanthipeptide
Lanthipeptides: B5772_RS02455_lanthipeptide
5
S S W P C G I G I T T T I C P T A V C T S K C
27
+S P C + +T I C P T V C++K C
3
T S I P C A V M A S T A I C P T L V C S N K C
25
40.6%
NZ_NUML01000015.1:
Lanthipeptides: COD66_RS20140_lanthipeptide
2
T T P S S W P C G I G I T T T I C P T A V C T S K C
27
T T P++ +G I+ +C P T C T S K C
7
T T P A T P T I V V G I S V G L C P T T K C T S K C
32

#### MIBiG 4.0 matches for E4J16_RS14990

28.6%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
17
I C P T A V C T S K C
27
C P T C T S K C
16
F C P T T K C T S K C
26
21.6%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
11
I G I T T T I C P T A V C T S K C
27
+G++ C P T C T S+C
21
V G V S A A F C P T T K C T S R C
37
allorf_0075864_0076013
Leader:
MAGVRGCARRRRGAAAAGA
Core:
V A S W G C G W A N C R G A L N R P S R A C S M V C V S P D
Core with dehydrations:
V A Dha W G Cys G W A N Cys R G A L N R P Dha R A Cys Dha M V Cys V Dha P D

#### antiSMASH-DB 4.0 matches for allorf_0075864_0076013

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0075864_0076013_lanthipeptide
Lanthipeptides: allorf_0075864_0076013_lanthipeptide
1
V A S W G C G W A N C R G A L N R P S R A C S M V C V S P D
30
V A S W G C G W A N C R G A L N R P S R A C S M V C V S P D
1
V A S W G C G W A N C R G A L N R P S R A C S M V C V S P D
30
30.3%
NC_015215.1 and 5 others:
NC_015215.1 Lanthipeptides: SGGBAA2069_RS00700_lanthipeptide NZ_JAKUYO010000004.1 Lanthipeptides: MK556_RS09790_lanthipeptide NZ_JAKUYO010000004.1 Lanthipeptides: MK556_RS09790_lanthipeptide NZ_JAMDHZ010000003.1 Lanthipeptides: M5Q10_RS05355_lanthipeptide NZ_JAMDHZ010000003.1 Lanthipeptides: M5Q10_RS05355_lanthipeptide
Lanthipeptides: SGGBAA2069_RS00700_lanthipeptide
5
G C G W A-----N C R G A L N R P S R A C S M V C V S P
29
G C W A + A L + + A C+ C P
4
G C A W A A V S A I S T V S A L F Q I T T A C T T R C Y H P
33
27.3%
NZ_QORY01000016.1 and 1 other:
NZ_QORY01000016.1 Lanthipeptides: DT250_RS18265_lanthipeptide
Lanthipeptides: DT250_RS18265_lanthipeptide
3
S W G C G W A N C R G A L N R P S R A C S M V C V
27
+W G C A P+ A C S C+
9
T W G C A I F T I A S A A Q C P T T A C S S K C L
33
with 1 more sequence matches
17.6%
NZ_KB913037.1:
Lanthipeptides: allorf_10324079_10324312_lanthipeptide
7
G W A N C R G A L N
16
G W+ C R G A+
7
G W S G C R G A I G
16

#### MIBiG 4.0 matches for allorf_0075864_0076013

16.7%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
6
C G W A N C R G A L N R P S R A C S M V
25
C W N L C++
1
C A W Y N I S C R L G N K G A Y C T L T
20
allorf_0076232_0076441
Leader:
MRGLQAEPARPPGPRGRAWGRASRPRPSVVMRRFVFGG
Core:
V G G A G R W F V G V L C A D L V C S P V R G L L R R F G V C
Core with dehydrations:
V G G A G R W F V G V L Cys A D L V Cys Dha P V R G L L R R F G V Cys

#### antiSMASH-DB 4.0 matches for allorf_0076232_0076441

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0076232_0076441_lanthipeptide
Lanthipeptides: allorf_0076232_0076441_lanthipeptide
1
V G G A G R W F V G V L C A D L V C S P V R G L L R R F G V C
31
V G G A G R W F V G V L C A D L V C S P V R G L L R R F G V C
1
V G G A G R W F V G V L C A D L V C S P V R G L L R R F G V C
31
25.8%
NZ_CP077072.1:
Lanthipeptides: allorf_4755020_4755199_lanthipeptide
3
G A G R W F V G V L C A D L V C S P V R G
23
G G W G+ C P+R G
5
G C G P W R S G L R C P S G K E E P L R G
25
19.2%
NZ_CP014326.1:
Lanthipeptides: AXK38_RS05515_lanthipeptide
3
G A G R W F V G V L C A D L V C S P V R G L L R R F
28
G A G W G+L A C+ + G+ R
28
G A G T W A G G I L G A Q Y-C T A I W G I A R S L
52
with 2 more sequence matches
14.0%
NZ_CP098485.1:
Lanthipeptides: allorf_6386875_6387051_lanthipeptide
2
G G A G R W F V G V L C A D L
16
G R W + L C A L
20
G A H S R W I I H F L C A A L
34
12.5%
NZ_KB899666.1:
Lanthipeptides: allorf_268670_268867_lanthipeptide
18
C S P V R G L L R
26
C+P V R G +R
6
C T P V R G E I R
14

#### MIBiG 4.0 matches for allorf_0076232_0076441

12.9%
BGC0002322.3 (CEJ66604.1):
Lasso peptide: citrocin
2
G G A G R W
7
G G G R+
13
G G V G R Y
18
9.7%
BGC0000563.4 (AEA03263.1):
Lanthipeptide: venezuelin
9
V G V L C A
14
+G+ C A
17
I G I S C A
22
allorf_0076338_0076511
Leader:
MGVWVEPGGGSSACFALTSSARRFAVYYA
Core:
G S V S A E G S G R V S D C L C K G C G P T Y K E T R G
Core with dehydrations:
G Dha V Dha A E G Dha G R V Dha D Cys L Cys K G Cys G P Dhb Y K E Dhb R G

#### antiSMASH-DB 4.0 matches for allorf_0076338_0076511

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0076338_0076511_lanthipeptide
Lanthipeptides: allorf_0076338_0076511_lanthipeptide
1
G S V S A E G S G R V S D C L C K G C G P T Y K E T R G
28
G S V S A E G S G R V S D C L C K G C G P T Y K E T R G
1
G S V S A E G S G R V S D C L C K G C G P T Y K E T R G
28
25.8%
NZ_CP023694.1:
Lanthipeptides: CP976_RS43015_lanthipeptide
3
V S A E G S G R V S D C L C K G C
19
V S A+ ++ C C K G C
11
V S A K K C T K I K T C T C K G C
27
19.5%
NZ_JALGRP010000007.1 and 1 other:
NZ_JALGRP010000007.1 Lanthipeptides: allorf_190248_190481_lanthipeptide
Lanthipeptides: allorf_190248_190481_lanthipeptide
6
E G S G R V S D C L C K G C G P T Y K E T
26
+G V+D C+ C G P +K +
21
K G Q T D V A D R R C R R C G P Q W K R S
41
with 3 more sequence matches
17.9%
NZ_BDFA01000012.1 and 5 others:
NZ_CP025018.1 Lanthipeptides: allorf_10559500_10559625_lanthipeptide NZ_CP029823.1 Lanthipeptides: allorf_10618379_10618504_lanthipeptide NZ_CP065050.1 Lanthipeptides: allorf_00914926_00915051_lanthipeptide NZ_JAALLH010000001.1 Lanthipeptides: allorf_0868535_0868660_lanthipeptide NZ_LJIW01000001.1 Lanthipeptides: allorf_0970869_0970994_lanthipeptide
Lanthipeptides: allorf_122369_122494_lanthipeptide
6
E G S G R V S D C L C K G C G P T Y K
24
+G R +C + P Y+
1
H A T G R F H E C A V E Q L P P L Y R
19
17.9%
NZ_CP019458.1:
Lanthipeptides: allorf_00977826_00977951_lanthipeptide
6
E G S G R V S D C L C K G C G P T Y K
24
+G R +C + P Y+
1
H A T G R F H E C T V E Q L P P L Y R
19
17.9%
NZ_WIXN01000006.1:
Lanthipeptides: allorf_110297_110410_lanthipeptide
9
G R V S D C L C K G C G P T Y
23
+ D C+ C G Y
2
A H L I D C I W N A C G I Y Y
16
allorf_0079268_0079333
Leader:
MKSCGSVDRVPGA
Core:
S R R K W C N L
Core with dehydrations:
Dha R R K W Cys N L

#### antiSMASH-DB 4.0 matches for allorf_0079268_0079333

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0079268_0079333_lanthipeptide
Lanthipeptides: allorf_0079268_0079333_lanthipeptide
1
S R R K W C N L
8
S R R K W C N L
1
S R R K W C N L
8
allorf_0079275_0079346
Leader:
MHHFRRDAPGT
Core:
R S T E P H D F N D L C
Core with dehydrations:
R Dha Dhb E P H D F N D L Cys

#### antiSMASH-DB 4.0 matches for allorf_0079275_0079346

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0079275_0079346_lanthipeptide
Lanthipeptides: allorf_0079275_0079346_lanthipeptide
1
R S T E P H D F N D L C
12
R S T E P H D F N D L C
1
R S T E P H D F N D L C
12
11.5%
NZ_CP011129.1 and 1 other:
NZ_CP013141.1 Lanthipeptides: allorf_5335460_5335672_lanthipeptide
Lanthipeptides: allorf_3828668_3828880_lanthipeptide
1
R S T E P H D
7
R+T E P H D
44
R T T E P H D
50
allorf_0079649_0079816
Leader:
MSVPFGSGVSGA
Core:
D A V G S P P V V V A D R D K C V R R P G C F P S A E R L R L M R L K E E P G P T I V
Core with dehydrations:
D A V G Dha P P V V V A D R D K Cys V R R P G Cys F P Dha A E R L R L M R L K E E P G P Dhb I V

#### antiSMASH-DB 4.0 matches for allorf_0079649_0079816

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0079649_0079816_lanthipeptide
Lanthipeptides: allorf_0079649_0079816_lanthipeptide
1
D A V G S P P V V V A D R D K C V R R P G C F P S A E R L R L M R L K E E P G P T I V
43
D A V G S P P V V V A D R D K C V R R P G C F P S A E R L R L M R L K E E P G P T I V
1
D A V G S P P V V V A D R D K C V R R P G C F P S A E R L R L M R L K E E P G P T I V
43
23.3%
NZ_CP077072.1:
Lanthipeptides: allorf_4755020_4755199_lanthipeptide
17
V R R P G C F P S A E R L R L M R L K E E P
38
R G C P L R K E E P
1
A R G D G C G P W R S G L R C P S G K E E P
22
16.7%
NZ_GL985606.1:
Lanthipeptides: allorf_0159575_0159772_lanthipeptide
8
V V V A D R D K C V R R--P G C F P S A E R
28
+ +R K R R P G P+A R
30
I A T T N R S K A A R R I R P G S P P T A S R
52
with 4 more sequence matches
16.3%
NZ_CABJAL010000004.1:
Lanthipeptides: allorf_113329_113490_lanthipeptide
16
C V R R P G C F P S A E R L R L M R L K
35
C+ C F S E L L+
22
C I N A T Q C F N S T E N L N T F Y L Q
41
14.0%
NZ_FNCC01000010.1:
Lanthipeptides: allorf_129310_129399_lanthipeptide
16
C V R R P G C F P S A E R L R L M
32
C V P C S A ++ +
1
C V M H P S C G V S A H S V K W V
17
14.0%
NZ_LACR01000015.1:
Lanthipeptides: allorf_040936_041022_lanthipeptide
13
R D K C V R R P G C
22
R++C R R G C
5
R N Q C H R R Y G C
14
11.3%
NZ_QRZZ01000003.1 and 2 others:
NZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03680_lanthipeptide NZ_QUKU01000006.1 Lanthipeptides: DXC27_RS05520_lanthipeptide
Lanthipeptides: DWV87_RS03215_lanthipeptide
16
C V R R P G C F P S A E R L R
30
V G C+P+A+R++
15
A V A M S G C Y P N A Q R I K
29
allorf_0090688_0090780
Leader:
MVMMNWSPGA
Core:
S R E A A C S W S Q P C G Q R G G P G R
Core with dehydrations:
Dha R E A A Cys Dha W Dha Q P Cys G Q R G G P G R

#### antiSMASH-DB 4.0 matches for allorf_0090688_0090780

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0090688_0090780_lanthipeptide
Lanthipeptides: allorf_0090688_0090780_lanthipeptide
1
S R E A A C S W S Q P C G Q R G G P G R
20
S R E A A C S W S Q P C G Q R G G P G R
1
S R E A A C S W S Q P C G Q R G G P G R
20
28.6%
NC_017765.1 and 2 others:
NZ_CP013219.1 Lanthipeptides: allorf_0171989_0172081_lanthipeptide NZ_KQ948355.1 Lanthipeptides: allorf_085143_085235_lanthipeptide
Lanthipeptides: allorf_01990982_01991074_lanthipeptide
9
S Q P C G Q R G G
17
+ P C G R G G
7
T S P C G G R G G
15
23.1%
NZ_BORO01000007.1 and 5 others:
NZ_JALASB010000016.1 Lanthipeptides: MOD42_RS18070_lanthipeptide NZ_JALASR010000012.1 Lanthipeptides: MOD87_RS16305_lanthipeptide NZ_JALAUW010000005.1 Lanthipeptides: MOE83_RS03160_lanthipeptide NZ_JALAXQ010000010.1 Lanthipeptides: MOF24_RS12150_lanthipeptide NZ_KZ454939.1 Lanthipeptides: CEF20_RS01155_lanthipeptide
Lanthipeptides: KI343_RS07745_lanthipeptide
1
S R E A A C S W S Q P
11
E A A C+W+ P
2
D M E A A C T W T L P
12
with 4 more sequence matches
19.2%
NC_017912.1 and 14 others:
NZ_CP007242.1 Lanthipeptides: KHU1_RS17410_lanthipeptide NZ_CP031424.1 Lanthipeptides: DXX91_RS18935_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS10440_lanthipeptide NZ_CP043809.1 Lanthipeptides: ETZ92_RS14260_lanthipeptide NZ_CP049904.1 Lanthipeptides: V753_RS18470_lanthipeptide NZ_CP053764.1 Lanthipeptides: HPQ66_RS18325_lanthipeptide NZ_CP061938.1 Lanthipeptides: IEN91_RS19800_lanthipeptide NZ_CP063768.1 Lanthipeptides: IM712_RS05205_lanthipeptide NZ_CP087137.1 Lanthipeptides: LOK79_RS18580_lanthipeptide NZ_CP092383.1 Lanthipeptides: MID02_RS19390_lanthipeptide NZ_JAEACM010000001.1 Lanthipeptides: I5F15_RS04355_lanthipeptide NZ_JAJNPN010000015.1 Lanthipeptides: LQ568_RS13285_lanthipeptide NZ_SDKF01000002.1 Lanthipeptides: EUA41_RS09950_lanthipeptide NZ_VDUT01000007.1 Lanthipeptides: FS412_RS14545_lanthipeptide
Lanthipeptides: MUS_RS20065_lanthipeptide
1
S R E A A C S W S Q P
11
E A A C+++ P
2
D M E A A C T F T L P
12
17.9%
NZ_CP025546.1 and 5 others:
NZ_CP025546.1 Lanthipeptides: allorf_4260056_4260220_lanthipeptide NZ_SDLM01000003.1 Lanthipeptides: allorf_121827_121991_lanthipeptide NZ_SDLM01000003.1 Lanthipeptides: allorf_121827_121991_lanthipeptide NZ_SDLN01000007.1 Lanthipeptides: allorf_135103_135267_lanthipeptide NZ_SDLN01000007.1 Lanthipeptides: allorf_135103_135267_lanthipeptide
Lanthipeptides: allorf_4260056_4260220_lanthipeptide
8
W S Q P C G Q R G G P
18
W+ P C G P
13
W A T P C S L N G N P
23
13.5%
NZ_LILB01000005.1:
Lanthipeptides: AMD00_RS23330_lanthipeptide
1
S R E A A C S W S Q P C
12
+++A C S+ P C
22
T K Q A G C S F I P P C
33
13.0%
NZ_CP046122.1:
Lanthipeptides: allorf_1397846_1398043_lanthipeptide
4
A A C S W S Q P C G Q R G G
17
+A C +Q P G+R G
32
S A C V A N Q P R G K R S G
45
allorf_0091131_0091220
Leader:
MGRRQGMASGG
Core:
G R F V C L P D G S S G S S N S S A
Core with dehydrations:
G R F V Cys L P D G Dha Dha G Dha Dha N Dha Dha A

#### antiSMASH-DB 4.0 matches for allorf_0091131_0091220

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0091131_0091220_lanthipeptide
Lanthipeptides: allorf_0091131_0091220_lanthipeptide
1
G R F V C L P D G S S G S S N S S A
18
G R F V C L P D G S S G S S N S S A
1
G R F V C L P D G S S G S S N S S A
18
26.3%
NZ_AUBN01000022.1:
Lanthipeptides: allorf_02867_02956_lanthipeptide
4
V C L P D G S S G S S N S
16
V C P G G +++
5
V C F P S G P V G P A H T
17

#### Lanthipeptide(s) for E4J16_RS00340

E4J16_RS14990
Leader:
MTHENLTGTYTASELEELNDISAYG
Core:
G T T P S S W P C G I G I T T T I C P T A V C T S K C R
Core with dehydrations:
G Dhb Dhb P Dha Dha W P Cys G I G I Dhb Dhb Dhb I Cys P Dhb A V Cys Dhb Dha K Cys R

#### antiSMASH-DB 4.0 matches for E4J16_RS14990

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: E4J16_RS14990_lanthipeptide
Lanthipeptides: E4J16_RS14990_lanthipeptide
1
G T T P S S W P C G I G I T T T I C P T A V C T S K C R
28
G T T P S S W P C G I G I T T T I C P T A V C T S K C R
1
G T T P S S W P C G I G I T T T I C P T A V C T S K C R
28
89.3%
NZ_CP025249.1 and 1 other:
NZ_CP025249.1 Lanthipeptides: CWT12_RS00390_lanthipeptide
Lanthipeptides: CWT12_RS00390_lanthipeptide
1
G T T P S S W P C G I G I T T T I C P T A V C T S K C R
28
G T T P S S W P C G I G I T T T+C P T A C+S K C R
1
G T T P S S W P C G I G I T T T V C P T A A C S S K C R
28
50.0%
NZ_LT630004.1:
Lanthipeptides: BQ5796_RS18310_lanthipeptide
5
S S W P C G I G I T T T I----C P T A V C T S K C
27
++ P C +G I T T I C P T C T S+C
2
T T L P C-V G I T V T I S V S M C P T T K C T S Q C
27
with 81 more sequence matches
Only the first 10 are displayed here.
46.9%
NC_021362.1 and 29 others:
NC_021362.1 Lanthipeptides: BALI_RS00915_lanthipeptide NZ_AP025342.1 Lanthipeptides: L6430_RS07475_lanthipeptide NZ_AP025342.1 Lanthipeptides: L6430_RS07475_lanthipeptide NZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20090_lanthipeptide NZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20090_lanthipeptide NZ_CP010524.1 Lanthipeptides: SC10_RS00915_lanthipeptide NZ_CP010524.1 Lanthipeptides: SC10_RS00915_lanthipeptide NZ_CP020352.1 Lanthipeptides: BLMD_RS01010_lanthipeptide NZ_CP020352.1 Lanthipeptides: BLMD_RS01010_lanthipeptide NZ_CP023168.1 Lanthipeptides: CK945_RS01010_lanthipeptide NZ_CP023168.1 Lanthipeptides: CK945_RS01010_lanthipeptide NZ_CP118744.1 Lanthipeptides: PWG69_RS01010_lanthipeptide NZ_CP118744.1 Lanthipeptides: PWG69_RS01010_lanthipeptide NZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20270_lanthipeptide NZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20270_lanthipeptide NZ_KN125579.1 Lanthipeptides: DJ88_RS03665_lanthipeptide NZ_KN125579.1 Lanthipeptides: DJ88_RS03665_lanthipeptide NZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19045_lanthipeptide NZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19045_lanthipeptide NZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16135_lanthipeptide NZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16135_lanthipeptide NZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11925_lanthipeptide NZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11925_lanthipeptide NZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01510_lanthipeptide NZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01510_lanthipeptide NZ_NKBC01000001.1 Lanthipeptides: CE036_RS00070_lanthipeptide NZ_NKBC01000001.1 Lanthipeptides: CE036_RS00070_lanthipeptide NZ_QXII01000007.1 Lanthipeptides: D1791_RS21810_lanthipeptide NZ_QXII01000007.1 Lanthipeptides: D1791_RS21810_lanthipeptide
Lanthipeptides: BALI_RS00915_lanthipeptide
2
T T P S S W P C G I G I T T T I C P T A V C T S K C
27
T T P S S P C G +T C P+ C T S C
7
T T P S S L P C G T L V T A V W C P S N A C T S D C
32
46.9%
NZ_CP006058.1 and 25 others:
NZ_CP006058.1 Lanthipeptides: BAMY6639_RS19790_lanthipeptide NZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptide NZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptide NZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptide NZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptide NZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptide NZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptide NZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptide NZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptide NZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptide NZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptide NZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptide NZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptide NZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptide NZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptide NZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptide NZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptide NZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptide NZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptide NZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptide NZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptide NZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptide NZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptide
Lanthipeptides: BAMY6639_RS19790_lanthipeptide
2
T T P S S W P C G I G I T T T I C P T A V C T S K C
27
T T P S S P C G+ +T C P+ C T S C
7
T T P S S L P C G V F V T A A F C P S T K C T S S C
32
46.9%
NZ_CP013862.1 and 1 other:
NZ_CP013862.1 Lanthipeptides: AOX59_RS09365_lanthipeptide
Lanthipeptides: AOX59_RS09365_lanthipeptide
2
T T P S S W P C G I G I T T T I C P T A V C T S K C
27
T T P S S C G I ++ C P T C T S+C
7
T T P S S V A C G I A V S A L F C P T T K C T S Q C
32
46.4%
NZ_CP084530.1 and 1 other:
NZ_CP084530.1 Lanthipeptides: LDO05_RS02090_lanthipeptide
Lanthipeptides: LDO05_RS02090_lanthipeptide
3
T P S S W P C G I G I T T T I C P T A V C T S K C
27
T S S W C G+ + C P+ C T S K C
5
T T S S W I C G V A-S A A F C P S T A C T S K C
28
45.5%
NZ_NTSF01000026.1 and 1 other:
NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21840_lanthipeptide
Lanthipeptides: CN325_RS21840_lanthipeptide
3
T P S S W P C G I G I T T T I----C P T A V C T S K C
27
T ++ P C G I G T T I C P T+ C T +C
1
T S T T V P C G I G S T I T I S I A Y C P T S K C T E R C
29
43.6%
NZ_CP009280.1 and 1 other:
NZ_CP009280.1 Lanthipeptides: P40081_RS37160_lanthipeptide
Lanthipeptides: P40081_RS37160_lanthipeptide
3
T P S S W P C G I G---I T T T I C P T A V C T S K C
27
T S S W P C I G I+ +C P T C T S K C
12
T T S S W P C V I G A V D I S A N L C P T T K C T S K C
39
41.9%
NC_018499.1 and 5 others:
NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide
Lanthipeptides: BCK_RS27845_lanthipeptide
2
T T P S S W P C G I G I T T T I C P T A V C T S K C
27
T T P++ P + ++ I C P T C T S K C
7
T T P A T-P T I V A V S L G I C P T T K C T S K C
31
41.9%
NZ_LT985747.1 and 1 other:
NZ_LT985747.1 Lanthipeptides: C8268_RS00150_lanthipeptide
Lanthipeptides: C8268_RS00150_lanthipeptide
1
G T T P S S W P C G I G I T T T I C P T A V C T S K C
27
G T S S W C G +T +C P+ C T C
6
G I T T S S W I C G F-V T A A L C P S T A C T G D C
31
41.4%
NZ_CP040938.1 and 1 other:
NZ_CP040938.1 Lanthipeptides: B5772_RS02455_lanthipeptide
Lanthipeptides: B5772_RS02455_lanthipeptide
5
S S W P C G I G I T T T I C P T A V C T S K C
27
+S P C + +T I C P T V C++K C
3
T S I P C A V M A S T A I C P T L V C S N K C
25
40.6%
NZ_NUML01000015.1:
Lanthipeptides: COD66_RS20140_lanthipeptide
2
T T P S S W P C G I G I T T T I C P T A V C T S K C
27
T T P++ +G I+ +C P T C T S K C
7
T T P A T P T I V V G I S V G L C P T T K C T S K C
32

#### MIBiG 4.0 matches for E4J16_RS14990

28.6%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
17
I C P T A V C T S K C
27
C P T C T S K C
16
F C P T T K C T S K C
26
21.6%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
11
I G I T T T I C P T A V C T S K C
27
+G++ C P T C T S+C
21
V G V S A A F C P T T K C T S R C
37
allorf_0075864_0076013
Leader:
MAGVRGCARRRRGAAAAGA
Core:
V A S W G C G W A N C R G A L N R P S R A C S M V C V S P D
Core with dehydrations:
V A Dha W G Cys G W A N Cys R G A L N R P Dha R A Cys Dha M V Cys V Dha P D

#### antiSMASH-DB 4.0 matches for allorf_0075864_0076013

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0075864_0076013_lanthipeptide
Lanthipeptides: allorf_0075864_0076013_lanthipeptide
1
V A S W G C G W A N C R G A L N R P S R A C S M V C V S P D
30
V A S W G C G W A N C R G A L N R P S R A C S M V C V S P D
1
V A S W G C G W A N C R G A L N R P S R A C S M V C V S P D
30
30.3%
NC_015215.1 and 5 others:
NC_015215.1 Lanthipeptides: SGGBAA2069_RS00700_lanthipeptide NZ_JAKUYO010000004.1 Lanthipeptides: MK556_RS09790_lanthipeptide NZ_JAKUYO010000004.1 Lanthipeptides: MK556_RS09790_lanthipeptide NZ_JAMDHZ010000003.1 Lanthipeptides: M5Q10_RS05355_lanthipeptide NZ_JAMDHZ010000003.1 Lanthipeptides: M5Q10_RS05355_lanthipeptide
Lanthipeptides: SGGBAA2069_RS00700_lanthipeptide
5
G C G W A-----N C R G A L N R P S R A C S M V C V S P
29
G C W A + A L + + A C+ C P
4
G C A W A A V S A I S T V S A L F Q I T T A C T T R C Y H P
33
27.3%
NZ_QORY01000016.1 and 1 other:
NZ_QORY01000016.1 Lanthipeptides: DT250_RS18265_lanthipeptide
Lanthipeptides: DT250_RS18265_lanthipeptide
3
S W G C G W A N C R G A L N R P S R A C S M V C V
27
+W G C A P+ A C S C+
9
T W G C A I F T I A S A A Q C P T T A C S S K C L
33
with 1 more sequence matches
17.6%
NZ_KB913037.1:
Lanthipeptides: allorf_10324079_10324312_lanthipeptide
7
G W A N C R G A L N
16
G W+ C R G A+
7
G W S G C R G A I G
16

#### MIBiG 4.0 matches for allorf_0075864_0076013

16.7%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
6
C G W A N C R G A L N R P S R A C S M V
25
C W N L C++
1
C A W Y N I S C R L G N K G A Y C T L T
20
allorf_0076232_0076441
Leader:
MRGLQAEPARPPGPRGRAWGRASRPRPSVVMRRFVFGG
Core:
V G G A G R W F V G V L C A D L V C S P V R G L L R R F G V C
Core with dehydrations:
V G G A G R W F V G V L Cys A D L V Cys Dha P V R G L L R R F G V Cys

#### antiSMASH-DB 4.0 matches for allorf_0076232_0076441

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0076232_0076441_lanthipeptide
Lanthipeptides: allorf_0076232_0076441_lanthipeptide
1
V G G A G R W F V G V L C A D L V C S P V R G L L R R F G V C
31
V G G A G R W F V G V L C A D L V C S P V R G L L R R F G V C
1
V G G A G R W F V G V L C A D L V C S P V R G L L R R F G V C
31
25.8%
NZ_CP077072.1:
Lanthipeptides: allorf_4755020_4755199_lanthipeptide
3
G A G R W F V G V L C A D L V C S P V R G
23
G G W G+ C P+R G
5
G C G P W R S G L R C P S G K E E P L R G
25
19.2%
NZ_CP014326.1:
Lanthipeptides: AXK38_RS05515_lanthipeptide
3
G A G R W F V G V L C A D L V C S P V R G L L R R F
28
G A G W G+L A C+ + G+ R
28
G A G T W A G G I L G A Q Y-C T A I W G I A R S L
52
with 2 more sequence matches
14.0%
NZ_CP098485.1:
Lanthipeptides: allorf_6386875_6387051_lanthipeptide
2
G G A G R W F V G V L C A D L
16
G R W + L C A L
20
G A H S R W I I H F L C A A L
34
12.5%
NZ_KB899666.1:
Lanthipeptides: allorf_268670_268867_lanthipeptide
18
C S P V R G L L R
26
C+P V R G +R
6
C T P V R G E I R
14

#### MIBiG 4.0 matches for allorf_0076232_0076441

12.9%
BGC0002322.3 (CEJ66604.1):
Lasso peptide: citrocin
2
G G A G R W
7
G G G R+
13
G G V G R Y
18
9.7%
BGC0000563.4 (AEA03263.1):
Lanthipeptide: venezuelin
9
V G V L C A
14
+G+ C A
17
I G I S C A
22
allorf_0076338_0076511
Leader:
MGVWVEPGGGSSACFALTSSARRFAVYYA
Core:
G S V S A E G S G R V S D C L C K G C G P T Y K E T R G
Core with dehydrations:
G Dha V Dha A E G Dha G R V Dha D Cys L Cys K G Cys G P Dhb Y K E Dhb R G

#### antiSMASH-DB 4.0 matches for allorf_0076338_0076511

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0076338_0076511_lanthipeptide
Lanthipeptides: allorf_0076338_0076511_lanthipeptide
1
G S V S A E G S G R V S D C L C K G C G P T Y K E T R G
28
G S V S A E G S G R V S D C L C K G C G P T Y K E T R G
1
G S V S A E G S G R V S D C L C K G C G P T Y K E T R G
28
25.8%
NZ_CP023694.1:
Lanthipeptides: CP976_RS43015_lanthipeptide
3
V S A E G S G R V S D C L C K G C
19
V S A+ ++ C C K G C
11
V S A K K C T K I K T C T C K G C
27
19.5%
NZ_JALGRP010000007.1 and 1 other:
NZ_JALGRP010000007.1 Lanthipeptides: allorf_190248_190481_lanthipeptide
Lanthipeptides: allorf_190248_190481_lanthipeptide
6
E G S G R V S D C L C K G C G P T Y K E T
26
+G V+D C+ C G P +K +
21
K G Q T D V A D R R C R R C G P Q W K R S
41
with 3 more sequence matches
17.9%
NZ_BDFA01000012.1 and 5 others:
NZ_CP025018.1 Lanthipeptides: allorf_10559500_10559625_lanthipeptide NZ_CP029823.1 Lanthipeptides: allorf_10618379_10618504_lanthipeptide NZ_CP065050.1 Lanthipeptides: allorf_00914926_00915051_lanthipeptide NZ_JAALLH010000001.1 Lanthipeptides: allorf_0868535_0868660_lanthipeptide NZ_LJIW01000001.1 Lanthipeptides: allorf_0970869_0970994_lanthipeptide
Lanthipeptides: allorf_122369_122494_lanthipeptide
6
E G S G R V S D C L C K G C G P T Y K
24
+G R +C + P Y+
1
H A T G R F H E C A V E Q L P P L Y R
19
17.9%
NZ_CP019458.1:
Lanthipeptides: allorf_00977826_00977951_lanthipeptide
6
E G S G R V S D C L C K G C G P T Y K
24
+G R +C + P Y+
1
H A T G R F H E C T V E Q L P P L Y R
19
17.9%
NZ_WIXN01000006.1:
Lanthipeptides: allorf_110297_110410_lanthipeptide
9
G R V S D C L C K G C G P T Y
23
+ D C+ C G Y
2
A H L I D C I W N A C G I Y Y
16
allorf_0079268_0079333
Leader:
MKSCGSVDRVPGA
Core:
S R R K W C N L
Core with dehydrations:
Dha R R K W Cys N L

#### antiSMASH-DB 4.0 matches for allorf_0079268_0079333

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0079268_0079333_lanthipeptide
Lanthipeptides: allorf_0079268_0079333_lanthipeptide
1
S R R K W C N L
8
S R R K W C N L
1
S R R K W C N L
8
allorf_0079275_0079346
Leader:
MHHFRRDAPGT
Core:
R S T E P H D F N D L C
Core with dehydrations:
R Dha Dhb E P H D F N D L Cys

#### antiSMASH-DB 4.0 matches for allorf_0079275_0079346

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0079275_0079346_lanthipeptide
Lanthipeptides: allorf_0079275_0079346_lanthipeptide
1
R S T E P H D F N D L C
12
R S T E P H D F N D L C
1
R S T E P H D F N D L C
12
11.5%
NZ_CP011129.1 and 1 other:
NZ_CP013141.1 Lanthipeptides: allorf_5335460_5335672_lanthipeptide
Lanthipeptides: allorf_3828668_3828880_lanthipeptide
1
R S T E P H D
7
R+T E P H D
44
R T T E P H D
50
allorf_0079649_0079816
Leader:
MSVPFGSGVSGA
Core:
D A V G S P P V V V A D R D K C V R R P G C F P S A E R L R L M R L K E E P G P T I V
Core with dehydrations:
D A V G Dha P P V V V A D R D K Cys V R R P G Cys F P Dha A E R L R L M R L K E E P G P Dhb I V

#### antiSMASH-DB 4.0 matches for allorf_0079649_0079816

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0079649_0079816_lanthipeptide
Lanthipeptides: allorf_0079649_0079816_lanthipeptide
1
D A V G S P P V V V A D R D K C V R R P G C F P S A E R L R L M R L K E E P G P T I V
43
D A V G S P P V V V A D R D K C V R R P G C F P S A E R L R L M R L K E E P G P T I V
1
D A V G S P P V V V A D R D K C V R R P G C F P S A E R L R L M R L K E E P G P T I V
43
23.3%
NZ_CP077072.1:
Lanthipeptides: allorf_4755020_4755199_lanthipeptide
17
V R R P G C F P S A E R L R L M R L K E E P
38
R G C P L R K E E P
1
A R G D G C G P W R S G L R C P S G K E E P
22
16.7%
NZ_GL985606.1:
Lanthipeptides: allorf_0159575_0159772_lanthipeptide
8
V V V A D R D K C V R R--P G C F P S A E R
28
+ +R K R R P G P+A R
30
I A T T N R S K A A R R I R P G S P P T A S R
52
with 4 more sequence matches
16.3%
NZ_CABJAL010000004.1:
Lanthipeptides: allorf_113329_113490_lanthipeptide
16
C V R R P G C F P S A E R L R L M R L K
35
C+ C F S E L L+
22
C I N A T Q C F N S T E N L N T F Y L Q
41
14.0%
NZ_FNCC01000010.1:
Lanthipeptides: allorf_129310_129399_lanthipeptide
16
C V R R P G C F P S A E R L R L M
32
C V P C S A ++ +
1
C V M H P S C G V S A H S V K W V
17
14.0%
NZ_LACR01000015.1:
Lanthipeptides: allorf_040936_041022_lanthipeptide
13
R D K C V R R P G C
22
R++C R R G C
5
R N Q C H R R Y G C
14
11.3%
NZ_QRZZ01000003.1 and 2 others:
NZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03680_lanthipeptide NZ_QUKU01000006.1 Lanthipeptides: DXC27_RS05520_lanthipeptide
Lanthipeptides: DWV87_RS03215_lanthipeptide
16
C V R R P G C F P S A E R L R
30
V G C+P+A+R++
15
A V A M S G C Y P N A Q R I K
29
allorf_0090688_0090780
Leader:
MVMMNWSPGA
Core:
S R E A A C S W S Q P C G Q R G G P G R
Core with dehydrations:
Dha R E A A Cys Dha W Dha Q P Cys G Q R G G P G R

#### antiSMASH-DB 4.0 matches for allorf_0090688_0090780

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0090688_0090780_lanthipeptide
Lanthipeptides: allorf_0090688_0090780_lanthipeptide
1
S R E A A C S W S Q P C G Q R G G P G R
20
S R E A A C S W S Q P C G Q R G G P G R
1
S R E A A C S W S Q P C G Q R G G P G R
20
28.6%
NC_017765.1 and 2 others:
NZ_CP013219.1 Lanthipeptides: allorf_0171989_0172081_lanthipeptide NZ_KQ948355.1 Lanthipeptides: allorf_085143_085235_lanthipeptide
Lanthipeptides: allorf_01990982_01991074_lanthipeptide
9
S Q P C G Q R G G
17
+ P C G R G G
7
T S P C G G R G G
15
23.1%
NZ_BORO01000007.1 and 5 others:
NZ_JALASB010000016.1 Lanthipeptides: MOD42_RS18070_lanthipeptide NZ_JALASR010000012.1 Lanthipeptides: MOD87_RS16305_lanthipeptide NZ_JALAUW010000005.1 Lanthipeptides: MOE83_RS03160_lanthipeptide NZ_JALAXQ010000010.1 Lanthipeptides: MOF24_RS12150_lanthipeptide NZ_KZ454939.1 Lanthipeptides: CEF20_RS01155_lanthipeptide
Lanthipeptides: KI343_RS07745_lanthipeptide
1
S R E A A C S W S Q P
11
E A A C+W+ P
2
D M E A A C T W T L P
12
with 4 more sequence matches
19.2%
NC_017912.1 and 14 others:
NZ_CP007242.1 Lanthipeptides: KHU1_RS17410_lanthipeptide NZ_CP031424.1 Lanthipeptides: DXX91_RS18935_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS10440_lanthipeptide NZ_CP043809.1 Lanthipeptides: ETZ92_RS14260_lanthipeptide NZ_CP049904.1 Lanthipeptides: V753_RS18470_lanthipeptide NZ_CP053764.1 Lanthipeptides: HPQ66_RS18325_lanthipeptide NZ_CP061938.1 Lanthipeptides: IEN91_RS19800_lanthipeptide NZ_CP063768.1 Lanthipeptides: IM712_RS05205_lanthipeptide NZ_CP087137.1 Lanthipeptides: LOK79_RS18580_lanthipeptide NZ_CP092383.1 Lanthipeptides: MID02_RS19390_lanthipeptide NZ_JAEACM010000001.1 Lanthipeptides: I5F15_RS04355_lanthipeptide NZ_JAJNPN010000015.1 Lanthipeptides: LQ568_RS13285_lanthipeptide NZ_SDKF01000002.1 Lanthipeptides: EUA41_RS09950_lanthipeptide NZ_VDUT01000007.1 Lanthipeptides: FS412_RS14545_lanthipeptide
Lanthipeptides: MUS_RS20065_lanthipeptide
1
S R E A A C S W S Q P
11
E A A C+++ P
2
D M E A A C T F T L P
12
17.9%
NZ_CP025546.1 and 5 others:
NZ_CP025546.1 Lanthipeptides: allorf_4260056_4260220_lanthipeptide NZ_SDLM01000003.1 Lanthipeptides: allorf_121827_121991_lanthipeptide NZ_SDLM01000003.1 Lanthipeptides: allorf_121827_121991_lanthipeptide NZ_SDLN01000007.1 Lanthipeptides: allorf_135103_135267_lanthipeptide NZ_SDLN01000007.1 Lanthipeptides: allorf_135103_135267_lanthipeptide
Lanthipeptides: allorf_4260056_4260220_lanthipeptide
8
W S Q P C G Q R G G P
18
W+ P C G P
13
W A T P C S L N G N P
23
13.5%
NZ_LILB01000005.1:
Lanthipeptides: AMD00_RS23330_lanthipeptide
1
S R E A A C S W S Q P C
12
+++A C S+ P C
22
T K Q A G C S F I P P C
33
13.0%
NZ_CP046122.1:
Lanthipeptides: allorf_1397846_1398043_lanthipeptide
4
A A C S W S Q P C G Q R G G
17
+A C +Q P G+R G
32
S A C V A N Q P R G K R S G
45
allorf_0091131_0091220
Leader:
MGRRQGMASGG
Core:
G R F V C L P D G S S G S S N S S A
Core with dehydrations:
G R F V Cys L P D G Dha Dha G Dha Dha N Dha Dha A

#### antiSMASH-DB 4.0 matches for allorf_0091131_0091220

100.0%
NZ_CP039292.1 and 1 other:
NZ_CP039292.1 Lanthipeptides: allorf_0091131_0091220_lanthipeptide
Lanthipeptides: allorf_0091131_0091220_lanthipeptide
1
G R F V C L P D G S S G S S N S S A
18
G R F V C L P D G S S G S S N S S A
1
G R F V C L P D G S S G S S N S S A
18
26.3%
NZ_AUBN01000022.1:
Lanthipeptides: allorf_02867_02956_lanthipeptide
4
V C L P D G S S G S S N S
16
V C P G G +++
5
V C F P S G P V G P A H T
17
allorf_0094300_0094539
Leader:
MVLGLGDGCHSQAPKPSPVRRSNPEALCPHARCRRKGGCQRVRWSRPPGQTPFCPAGRACYSRPRGADSASA
Core:
L C S S S V R
Core with dehydrations:
L Cys Dha Dha Dha V R

#### antiSMASH-DB 4.0 matches for allorf_0094300_0094539

100.0%
NZ_CP039292.1:
Lanthipeptides: allorf_0094300_0094539_lanthipeptide
1
L C S S S V R
7
L C S S S V R
1
L C S S S V R
7
allorf_0094578_0094799
Leader:
MRHIQFGYVNDAGEIRANDSLGEAVTWMGDGGSAGA
Core:
A A A G V V S P R S D T D M A M A E R V R R E R M C E D F L T V V D P V G
Core with dehydrations:
A A A G V V Dha P R Dha D Dhb D M A M A E R V R R E R M Cys E D F L Dhb V V D P V G

#### antiSMASH-DB 4.0 matches for allorf_0094578_0094799

100.0%
NZ_CP039292.1:
Lanthipeptides: allorf_0094578_0094799_lanthipeptide
1
A A A G V V S P R S D T D M A M A E R V R R E R M C E D F L T V V D P V G
37
A A A G V V S P R S D T D M A M A E R V R R E R M C E D F L T V V D P V G
1
A A A G V V S P R S D T D M A M A E R V R R E R M C E D F L T V V D P V G
37
45.5%
NZ_CP025249.1 and 1 other:
NZ_CP025249.1 Lanthipeptides: allorf_0098372_0098596_lanthipeptide
Lanthipeptides: allorf_0098372_0098596_lanthipeptide
1
A A A G V V S P R S D T D M A M A E R V R R E R M C E D F L T V V D P V G
37
A G+ S P R S D T D M A M A E R V R R E M C D F L+V V D P V G
30
A T E G L A S P R S D T D M A M A E R V R R E H M C G D F L S V V D P V G
66
allorf_0094630_0094776
Leader:
MIRSVRRLHGWEMGVRRVLLRRELSAPGA
Core:
I R T W R W Q R G C E G N A C A R T S
Core with dehydrations:
I R Dhb W R W Q R G Cys E G N A Cys A R Dhb Dha

#### antiSMASH-DB 4.0 matches for allorf_0094630_0094776

100.0%
NZ_CP039292.1:
Lanthipeptides: allorf_0094630_0094776_lanthipeptide
1
I R T W R W Q R G C E G N A C A R T S
19
I R T W R W Q R G C E G N A C A R T S
1
I R T W R W Q R G C E G N A C A R T S
19
39.0%
NZ_CP025249.1 and 1 other:
NZ_CP025249.1 Lanthipeptides: allorf_0098430_0098639_lanthipeptide
Lanthipeptides: allorf_0098430_0098639_lanthipeptide
1
I R T W R W Q R G C E G N A C A R T S
19
I+T W R W Q R G C E G N C A T S
1
I Q T W R W Q R G C E G N T C A V T S
19
31.6%
NZ_CP031746.1:
Lanthipeptides: allorf_1813942_1814025_lanthipeptide
1
I R T W R W Q R G C E G
12
+R T W+ G C G
2
L R T V A W R P G C P G
13
with 3 more sequence matches
31.6%
NZ_LMGK01000023.1 and 1 other:
NZ_RCNY01000084.1 Lanthipeptides: allorf_084168_084254_lanthipeptide
Lanthipeptides: allorf_096724_096810_lanthipeptide
11
E G N A C A
16
E G N A C A
9
E G N A C A
14
22.2%
NZ_CP054919.1 and 1 other:
NZ_CP054919.1 Lanthipeptides: HUT16_RS27255_lanthipeptide
Lanthipeptides: HUT16_RS27255_lanthipeptide
10
C E G N A C A
16
C E G+A C A
15
C E G S A C A
21
15.4%
NZ_LR134504.1:
Lanthipeptides: allorf_1619680_1619865_lanthipeptide
4
W R W Q R G C E G N A C
15
R W + C G+A C
15
L R W A K S C L G S A C
26

#### MIBiG 4.0 matches for allorf_0094630_0094776

18.2%
BGC0000563.4 (AEA03263.1):
Lanthipeptide: venezuelin
10
C E G N A C A
16
C G +C A
16
C I G I S C A
22
allorf_0097938_0098072
Leader:
MTHATSKHRLHNTFLSRRSFGQSEDAIAG
Core:
I R E C S G F P P R P V L P W
Core with dehydrations:
I R E Cys Dha G F P P R P V L P W

#### antiSMASH-DB 4.0 matches for allorf_0097938_0098072

100.0%
NZ_CP039292.1:
Lanthipeptides: allorf_0097938_0098072_lanthipeptide
1
I R E C S G F P P R P V L P W
15
I R E C S G F P P R P V L P W
1
I R E C S G F P P R P V L P W
15
15.4%
NZ_BMJA01000007.1:
Lanthipeptides: allorf_022673_022864_lanthipeptide
2
R E C S G F P P R P
11
R C+G F P P
29
R V C T G F R P S P
38

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
No hits above weak threshold.
Weak hits (5):
HipB
Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 19.59 out of 33.73
Confidence: weak
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 19.18 out of 30.25
Confidence: weak
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 15.27 out of 18.57
Confidence: weak
FuR variant 2
Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 22.76 out of 32.74
Confidence: weak
FuR variant 2
Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 22.63 out of 32.74
Confidence: weak
Lanthipeptides
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

E4J16_RS14990 - Class II
  Cleavage pHMM score: -6.30
  RODEO score: 0
  Monoisotopic mass: 2660.3 Da
  Molecular weight: 2662.1 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2680.1 Da N = 1
    2698.1 Da N = 2
    2716.2 Da N = 3
    2734.2 Da N = 4
    2752.2 Da N = 5
    2770.2 Da N = 6
allorf_0075864_0076013 - Class II
  Cleavage pHMM score: -3.60
  RODEO score: 0
  Monoisotopic mass: 3080.4 Da
  Molecular weight: 3082.5 Da
  Number of bridges: 4
allorf_0076232_0076441 - Class II
  Cleavage pHMM score: -5.60
  RODEO score: 0
  Monoisotopic mass: 3243.7 Da
  Molecular weight: 3245.9 Da
  Number of bridges: 1
allorf_0076338_0076511 - Class II
  Cleavage pHMM score: -4.20
  RODEO score: 0
  Monoisotopic mass: 2695.3 Da
  Molecular weight: 2697.0 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2715.0 Da N = 1
    2733.0 Da N = 2
    2751.0 Da N = 3
allorf_0079268_0079333 - Class II
  Cleavage pHMM score: -4.10
  RODEO score: 0
  Monoisotopic mass: 1043.6 Da
  Molecular weight: 1044.2 Da
  Number of bridges: 1
allorf_0079275_0079346 - Class II
  Cleavage pHMM score: -7.30
  RODEO score: 0
  Monoisotopic mass: 1396.6 Da
  Molecular weight: 1397.5 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1415.5 Da N = 1
allorf_0079649_0079816 - Class II
  Cleavage pHMM score: -4.80
  RODEO score: 0
  Monoisotopic mass: 4661.5 Da
  Molecular weight: 4664.4 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4682.4 Da N = 1
allorf_0090688_0090780 - Class II
  Cleavage pHMM score: -6.30
  RODEO score: 0
  Monoisotopic mass: 2034.9 Da
  Molecular weight: 2036.2 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2054.2 Da N = 1
allorf_0091131_0091220 - Class II
  Cleavage pHMM score: -5.90
  RODEO score: 0
  Monoisotopic mass: 1618.8 Da
  Molecular weight: 1619.7 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1637.7 Da N = 1
    1655.7 Da N = 2
    1673.7 Da N = 3
    1691.8 Da N = 4
    1709.8 Da N = 5
E4J16_RS14990 - Class II
  Cleavage pHMM score: -6.30
  RODEO score: 0
  Monoisotopic mass: 2660.3 Da
  Molecular weight: 2662.1 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2680.1 Da N = 1
    2698.1 Da N = 2
    2716.2 Da N = 3
    2734.2 Da N = 4
    2752.2 Da N = 5
    2770.2 Da N = 6
allorf_0075864_0076013 - Class II
  Cleavage pHMM score: -3.60
  RODEO score: 0
  Monoisotopic mass: 3080.4 Da
  Molecular weight: 3082.5 Da
  Number of bridges: 4
allorf_0076232_0076441 - Class II
  Cleavage pHMM score: -5.60
  RODEO score: 0
  Monoisotopic mass: 3243.7 Da
  Molecular weight: 3245.9 Da
  Number of bridges: 1
allorf_0076338_0076511 - Class II
  Cleavage pHMM score: -4.20
  RODEO score: 0
  Monoisotopic mass: 2695.3 Da
  Molecular weight: 2697.0 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2715.0 Da N = 1
    2733.0 Da N = 2
    2751.0 Da N = 3
allorf_0079268_0079333 - Class II
  Cleavage pHMM score: -4.10
  RODEO score: 0
  Monoisotopic mass: 1043.6 Da
  Molecular weight: 1044.2 Da
  Number of bridges: 1
allorf_0079275_0079346 - Class II
  Cleavage pHMM score: -7.30
  RODEO score: 0
  Monoisotopic mass: 1396.6 Da
  Molecular weight: 1397.5 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1415.5 Da N = 1
allorf_0079649_0079816 - Class II
  Cleavage pHMM score: -4.80
  RODEO score: 0
  Monoisotopic mass: 4661.5 Da
  Molecular weight: 4664.4 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4682.4 Da N = 1
allorf_0090688_0090780 - Class II
  Cleavage pHMM score: -6.30
  RODEO score: 0
  Monoisotopic mass: 2034.9 Da
  Molecular weight: 2036.2 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2054.2 Da N = 1
allorf_0091131_0091220 - Class II
  Cleavage pHMM score: -5.90
  RODEO score: 0
  Monoisotopic mass: 1618.8 Da
  Molecular weight: 1619.7 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1637.7 Da N = 1
    1655.7 Da N = 2
    1673.7 Da N = 3
    1691.8 Da N = 4
    1709.8 Da N = 5
allorf_0094300_0094539 - Class II
  Cleavage pHMM score: -6.20
  RODEO score: 0
  Monoisotopic mass: 696.4 Da
  Molecular weight: 696.8 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    714.8 Da N = 1
    732.8 Da N = 2
allorf_0094578_0094799 - Class II
  Cleavage pHMM score: -2.40
  RODEO score: 0
  Monoisotopic mass: 3963.9 Da
  Molecular weight: 3966.5 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3984.5 Da N = 1
    4002.5 Da N = 2
    4020.5 Da N = 3
allorf_0094630_0094776 - Class II
  Cleavage pHMM score: -5.90
  RODEO score: 0
  Monoisotopic mass: 2196.1 Da
  Molecular weight: 2197.5 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2215.5 Da N = 1
allorf_0097938_0098072 - Class II
  Cleavage pHMM score: -7.00
  RODEO score: 0
  Monoisotopic mass: 1734.9 Da
  Molecular weight: 1736.0 Da
  Number of bridges: 1

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---

NZ_CP039292.1 - Region 2 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,838,244 - 1,859,425 nt. (total: 21,182 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Transferases: phosphorylase
E4J16_RS07405: thiamine-phosphate pyrophosphorylase

smcogs
  SMCOG1280: thiamine-phosphate pyrophosphorylase

Ligases: synthetase
E4J16_RS07420: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000677.5 |  | 0.38 | terpene | cyclooctatin | Streptomyces melanosporofaciens
BGC0002309.2 |  | 0.37 | terpene | cattleyene | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0001911.3 |  | 0.34 | terpene | raimonol | Streptomyces anulatus
BGC0001456.3 |  | 0.34 | terpene | isorenieratene | Streptomyces argillaceus
BGC0001910.4 |  | 0.33 | terpene | cyslabdan A, cyslabdan B, cyslabdan C | Streptomyces cyslabdanicus
BGC0000665.5 |  | 0.33 | other (other), terpene | xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C | Streptomyces sp. HKI0576
BGC0001521.3 |  | 0.33 | NRPS | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0002339.3 |  | 0.33 | terpene | 2-hydroxysorangiadenosine | Vitiosangium cumulatum
BGC0000936.5 |  | 0.32 | other (other) | pyocyanine | Pseudomonas aeruginosa PAO1
BGC0000664.5 |  | 0.32 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000677.5 |  | 0.38 | terpene | cyclooctatin | Streptomyces melanosporofaciens
BGC0002309.2 |  | 0.37 | terpene | cattleyene | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0001911.3 |  | 0.34 | terpene | raimonol | Streptomyces anulatus
BGC0001456.3 |  | 0.34 | terpene | isorenieratene | Streptomyces argillaceus
BGC0001910.4 |  | 0.33 | terpene | cyslabdan A, cyslabdan B, cyslabdan C | Streptomyces cyslabdanicus
BGC0000665.5 |  | 0.33 | other (other), terpene | xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C | Streptomyces sp. HKI0576
BGC0001521.3 |  | 0.33 | NRPS | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0002339.3 |  | 0.33 | terpene | 2-hydroxysorangiadenosine | Vitiosangium cumulatum
BGC0000936.5 |  | 0.32 | other (other) | pyocyanine | Pseudomonas aeruginosa PAO1
BGC0000664.5 |  | 0.32 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP
diterpene precursor |  | GGPP | C20 | acyclic | PP
sesterterpene precursor |  | GFPP | C25 | acyclic | PP
triterpene precursor |  | HPP | C30 | acyclic | PP

Genes with terpene domains:
E4J16_RS07420: PT_FPPS_like
Domain 1 (48 - 392): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: unknown

Reactions:
  IPP, DMAPP → FPP
  IPP, DMAPP → GGPP
  IPP, DMAPP → GFPP
  IPP, DMAPP → HPP

Terpene
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
GFPP | Geranylfarnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
HPP | Hexaprenyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate