GCF_004332015.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP028720.1 (Enterococcus faecalis)

Region	Type	From	To
Region 1.1	terpene-precursor	142,809	163,690
Region 1.2	darobactin	894,027	915,034
Region 1.3	RiPP-like	1,445,448	1,456,491
Region 1.4	cyclic-lactone-autoinducer	2,316,517	2,337,245

NZ_CP028721.1 (Enterococcus faecalis)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 2.1	lanthipeptide-class-ii	28,909	51,890	High	cytolysin ClyLl/cytolysin ClyLs	ribosomal:RiPP:Lanthipeptide

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1.1	terpene-precursor	142,809	163,690
Region 1.2	darobactin	894,027	915,034
Region 1.3	RiPP-like	1,445,448	1,456,491
Region 1.4	cyclic-lactone-autoinducer	2,316,517	2,337,245
Region 2.1	lanthipeptide-class-ii	28,909	51,890	High	cytolysin ClyLl/cytolysin ClyLs	ribosomal:RiPP:Lanthipeptide

No secondary metabolite regions were found in these records:: NZ_CP028722.1 (Enterococcus faecalis); NZ_CP028723.1 (Enterococcus faecalis)

Compact view

NZ_CP028720.1 - Region 1 - terpene-precursor

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Location: 142,809 - 163,690 nt. (total: 20,882 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: peptidase

C7I32_RS00915: methionine aminopeptidase

smcogs: SMCOG1172: methionine aminopeptidase

Ligases: synthetase

C7I32_RS00880: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.39	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0002309.2	0.36	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000639.3	0.34	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.34	terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0001605.3	0.32	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0001075.5	0.31	PKS, terpene	aurachin RE	Rhodococcus erythropolis
BGC0001456.3	0.30	terpene	isorenieratene	Streptomyces argillaceus
BGC0000286.3	0.30	PKS	viguiepinol	Streptomyces sp. KO-3988

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.39	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0002309.2	0.36	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000639.3	0.34	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.34	terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0001605.3	0.32	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0001075.5	0.31	PKS, terpene	aurachin RE	Rhodococcus erythropolis
BGC0001456.3	0.30	terpene	isorenieratene	Streptomyces argillaceus
BGC0000286.3	0.30	PKS	viguiepinol	Streptomyces sp. KO-3988

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor		FPP	C15	acyclic	PP

Genes with terpene domains:

C7I32_RS00880: PT_FPPS_like

Domain 1 (29 - 276): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:: DMAPP, IPP → FPP

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57

Confidence: strong

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 25.18 out of 26.06

Confidence: strong

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.38 out of 27.78

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.87 out of 28.19

Confidence: medium

Additional weak hits (1):

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.64 out of 29.38

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
MogR	Repressor of flagellar motility genes
ToxT	Regulator of MSHA biosynthesis
ZuR variant 1	Zinc-responsive repressor

NZ_CP028720.1 - Region 2 - darobactin

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Location: 894,027 - 915,034 nt. (total: 21,008 nt) Show pHMM detection rules used

darobactin: ((cds(PF04055 and (TIGR04085 or SPASM)) and darobactin_precursor) or darobactin_rSAM)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Ligases: synthase

C7I32_RS04835: carbamoyl phosphate synthase small subunit

smcogs: SMCOG1249: carbamoyl phosphate synthase small subunit

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000883.5	0.36	other (other)	arginomycin	Streptomyces arginensis
BGC0000875.4	0.30	other (nucleoside), saccharide	caprazamycin, caprazamycin aglycon	Streptomyces sp. MK730-62F2
BGC0000207.5	0.30	PKS	chartreusin	Streptomyces chartreusis
BGC0000872.5	0.30	other (other)	A-90289 A, A-90289 B	Streptomyces sp. SANK 60405
BGC0001076.5	0.30	other (nucleoside)	liposidomycin B, liposidomycin A, liposidomycin C, liposidomycin Z, liposidomycin H, liposidomycin G, liposidomycin L, liposidomycin M, liposidomycin K, liposidomycin N	Streptomyces sp. SN-1061M
BGC0002359.3	0.29	NRPS	dudomycin A	Streptomyces albus subsp. chlorinus
BGC0001835.2	0.25	PKS	gynuellalide	Gynuella sunshinyii YC6258
BGC0001812.3	0.25	PKS	tylactone	Micromonospora chalcea subsp. izumensis
BGC0000804.5	0.24	saccharide	acarviostatin I03, acarviostatin II03, acarviostatin III03, acarviostatin IV03	Streptomyces coelicoflavus ZG0656
BGC0000907.5	0.24	other (other)	lincomycin	Streptomyces lincolnensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000883.5	0.36	other (other)	arginomycin	Streptomyces arginensis
BGC0000875.4	0.30	other (nucleoside), saccharide	caprazamycin, caprazamycin aglycon	Streptomyces sp. MK730-62F2
BGC0000207.5	0.30	PKS	chartreusin	Streptomyces chartreusis
BGC0000872.5	0.30	other (other)	A-90289 A, A-90289 B	Streptomyces sp. SANK 60405
BGC0001076.5	0.30	other (nucleoside)	liposidomycin B, liposidomycin A, liposidomycin C, liposidomycin Z, liposidomycin H, liposidomycin G, liposidomycin L, liposidomycin M, liposidomycin K, liposidomycin N	Streptomyces sp. SN-1061M
BGC0002359.3	0.29	NRPS	dudomycin A	Streptomyces albus subsp. chlorinus
BGC0001835.2	0.25	PKS	gynuellalide	Gynuella sunshinyii YC6258
BGC0001812.3	0.25	PKS	tylactone	Micromonospora chalcea subsp. izumensis
BGC0000804.5	0.24	saccharide	acarviostatin I03, acarviostatin II03, acarviostatin III03, acarviostatin IV03	Streptomyces coelicoflavus ZG0656
BGC0000907.5	0.24	other (other)	lincomycin	Streptomyces lincolnensis

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 25.80 out of 29.38

Confidence: medium

Additional weak hits (2):

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.86 out of 29.38

Confidence: weak

NrtR

Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 24.09 out of 35.63

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
FuR variant 1	Ferric Uptake Regulator

NZ_CP028720.1 - Region 3 - RiPP-like

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Location: 1,445,448 - 1,456,491 nt. (total: 11,044 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: acetyltransferase

C7I32_RS07485: Chloramphenicol acetyltransferase

smcogs: SMCOG1156: Chloramphenicol acetyltransferase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001510.5	0.31	other (other)	anisomycin	Streptomyces hygrospinosus
BGC0000770.4	0.31	saccharide	lipo-oligosaccharide	Campylobacter jejuni
BGC0000762.3	0.27	saccharide	exopolysaccharide	Rhizobium leguminosarum bv. viciae
BGC0000298.5	0.25	NRPS	aeruginosin 98-A, aeruginosin 98-B, aeruginosin 98-C	Microcystis aeruginosa NIES-98
BGC0000795.3	0.24	saccharide	S-layer glycan	Aneurinibacillus thermoaerophilus
BGC0000806.5	0.24	saccharide	phosphonoglycans	Glycomyces sp. NRRL B-16210
BGC0001412.3	0.24	saccharide	polysaccharide C	Bacteroides fragilis
BGC0001894.2	0.21	saccharide	heteropolysaccharide (HePS)	Lactobacillus plantarum
BGC0002550.2	0.19	PKS	lobophorin CR4	Streptomyces olivaceus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001510.5	0.31	other (other)	anisomycin	Streptomyces hygrospinosus
BGC0000770.4	0.31	saccharide	lipo-oligosaccharide	Campylobacter jejuni
BGC0000762.3	0.27	saccharide	exopolysaccharide	Rhizobium leguminosarum bv. viciae
BGC0000298.5	0.25	NRPS	aeruginosin 98-A, aeruginosin 98-B, aeruginosin 98-C	Microcystis aeruginosa NIES-98
BGC0000795.3	0.24	saccharide	S-layer glycan	Aneurinibacillus thermoaerophilus
BGC0000806.5	0.24	saccharide	phosphonoglycans	Glycomyces sp. NRRL B-16210
BGC0001412.3	0.24	saccharide	polysaccharide C	Bacteroides fragilis
BGC0001894.2	0.21	saccharide	heteropolysaccharide (HePS)	Lactobacillus plantarum
BGC0002550.2	0.19	PKS	lobophorin CR4	Streptomyces olivaceus

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

AfsR

Description: Pleiotropic regulatory for antibiotic production
Species: Streptomyces coelicolor
Score: 18.76 out of 23.05

Confidence: medium

Additional weak hits (2):

RicR

Description: Copper-responsive regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 21.43 out of 32.93

Confidence: weak

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 19.95 out of 25.88

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
AfsR	Pleiotropic regulatory for antibiotic production

NZ_CP028720.1 - Region 4 - cyclic-lactone-autoinducer

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Location: 2,316,517 - 2,337,245 nt. (total: 20,729 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001291.3	0.41	ribosomal	enterocin NKR-5-3B	Enterococcus faecium
BGC0001948.3	0.37	other (other)	naseseazine C, C3-aryl pyrroloindolines	Streptomyces sp.
BGC0000046.4	0.35	PKS	depudecin	Alternaria brassicicola
BGC0002227.3	0.31	NRPS	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0002667.2	0.30	ribosomal	estericin A	Clostridium estertheticum
BGC0001246.3	0.30	PKS	trans-resorcylide	Sarocladium zeae
BGC0000045.3	0.29	PKS	dehydrocurvularin	Aspergillus terreus
BGC0000676.5	0.29	terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae
BGC0000688.4	0.29	terpene	copalyl diphosphate	Diaporthe amygdali
BGC0001954.2	0.28	NRPS, PKS	wortmanamide A, wortmanamide B	Talaromyces wortmannii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001291.3	0.41	ribosomal	enterocin NKR-5-3B	Enterococcus faecium
BGC0001948.3	0.37	other (other)	naseseazine C, C3-aryl pyrroloindolines	Streptomyces sp.
BGC0000046.4	0.35	PKS	depudecin	Alternaria brassicicola
BGC0002227.3	0.31	NRPS	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0002667.2	0.30	ribosomal	estericin A	Clostridium estertheticum
BGC0001246.3	0.30	PKS	trans-resorcylide	Sarocladium zeae
BGC0000045.3	0.29	PKS	dehydrocurvularin	Aspergillus terreus
BGC0000676.5	0.29	terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae
BGC0000688.4	0.29	terpene	copalyl diphosphate	Diaporthe amygdali
BGC0001954.2	0.28	NRPS, PKS	wortmanamide A, wortmanamide B	Talaromyces wortmannii

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.50 out of 23.79

Confidence: medium

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.08 out of 23.79

Confidence: medium

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 28.99 out of 30.25

Confidence: strong

CRP

Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.55 out of 19.26

Confidence: medium

Additional weak hits (1):

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 23.02 out of 28.14

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
CRP	Cyclic AMP receptor protein
ColR	Phenol-responsive regulator
IolR	Regulator of the inositol catabolism

NZ_CP028721.1 - Region 1 - lanthipeptide-class-ii

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Location: 28,909 - 51,890 nt. (total: 22,982 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: protease

C7I32_RS15460: alkaline serine protease, subtilase family

smcogs: SMCOG1075: alkaline serine protease, subtilase family

Lyases: cyclase

C7I32_RS15470: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000504.5	1.00	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000500.5	0.53	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0001407.5	0.50	ribosomal	bicereucin	Bacillus cereus SJ1
BGC0000525.5	0.50	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000623.3	0.49	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000516.4	0.47	ribosomal	geobacillin II	Geobacillus thermodenitrificans
BGC0002698.2	0.47	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566
BGC0002674.2	0.46	ribosomal	enterocin F4-9	Enterococcus faecalis
BGC0001210.5	0.45	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000502.5	0.45	ribosomal	cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7	Bacillus cereus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000504.5	1.00	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000500.5	0.53	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0001407.5	0.50	ribosomal	bicereucin	Bacillus cereus SJ1
BGC0000525.5	0.50	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000623.3	0.49	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000516.4	0.47	ribosomal	geobacillin II	Geobacillus thermodenitrificans
BGC0002698.2	0.47	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566
BGC0002674.2	0.46	ribosomal	enterocin F4-9	Enterococcus faecalis
BGC0001210.5	0.45	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000502.5	0.45	ribosomal	cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7	Bacillus cereus

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for C7I32_RS15470

C7I32_RS16360

Leader:

MLLSMNITVTEIFM

Core:

KTYDYRGSVIKEGNKTTSIAYVQCACGCLASRMSSDSDKYKCSWCKRTYMLGKEIYR

Core with dehydrations:

KDhbYDYRGDhaVIKEGNKDhbDhbDhaIAYVQCysACysGCysLADhaRMDhaDhaDDhaDKYKCysDhaWCysKRDhbYMLGKEIYR

antiSMASH-DB 4.0 matches for C7I32_RS16360

100.0%

NZ_CP028721.1and 1 other:

NZ_JAQKZU010000014.1 Lanthipeptides: PMV60_RS12570_lanthipeptide

Lanthipeptides: C7I32_RS16360_lanthipeptide

KTYDYRGSVIKEGNKTTSIAYVQCACGCLASRMSSDSDKYKCSWCKRTYMLGKEIYR

15.8%

NZ_AP019008.1and 1 other:

NZ_BDDX01000012.1 Lanthipeptides: FF306_RS05510_lanthipeptide

Lanthipeptides: FF306_RS00060_lanthipeptide

AYVQCACGCLASRMSSDSDKYKCSWCK

+YV C GC+ R+ ++K K C

SYVLCTPGCITGRLMGCNNKTKTCHCH

15.8%

NZ_JXCW01000008.1:

Lanthipeptides: RZ55_RS07215_lanthipeptide

AYVQCACGCLASRMSSDSDKYKCSWCKRTY

+YV C GC+ R+ ++K K C ++

SYVLCTPGCITGRLMGCNNKTKTCHCHSSH

with 3 more sequence matches

14.0%

NZ_KV815277.1:

Lanthipeptides: allorf_240001_240225_lanthipeptide

CLASRMSSDSDKYKCSWCKRTYM

CL+ S + +CS C R+Y

CLSGAASPSTPTRECSECSRSYT

14.0%

NZ_KZ859514.1:

Lanthipeptides: DPQ64_RS19145_lanthipeptide

KTTSIAYVQCACGCLASRMSSD

K T I + C+C C+ S+ D

KITGIWSLDCSCTCMCSQWCGD

10.5%

NZ_CM002330.1and 4 others:

NZ_CP085885.1 Lanthipeptides: allorf_5880464_5880601_lanthipeptideNZ_CP099610.1 Lanthipeptides: allorf_5773509_5773646_lanthipeptideNZ_RHRT01000002.1 Lanthipeptides: allorf_000661_000798_lanthipeptideNZ_RHRW01000002.1 Lanthipeptides: allorf_440068_440205_lanthipeptide

Lanthipeptides: allorf_5814187_5814324_lanthipeptide

KTTSIAYVQCACGC

K+T I+++ CA C

KSTGISFLHCAHHC

C7I32_RS15475

Leader:

MLNKENQENYYSNKLELVGPSFEELSLEEMEAIQGS

Core:

GDVQAETTPACFTIGLGVGALFSAKFC

Core with dehydrations:

GDVQAEDhbDhbPACysFDhbIGLGVGALFDhaAKFCys

antiSMASH-DB 4.0 matches for C7I32_RS15475

100.0%

NZ_AP026721.1and 35 others:

NZ_CP015883.1 Lanthipeptides: A6B47_RS00875_lanthipeptideNZ_CP028286.1 Lanthipeptides: CEQ02_RS16115_lanthipeptideNZ_CP028721.1 Lanthipeptides: C7I32_RS15475_lanthipeptideNZ_CP028835.1 Lanthipeptides: C9432_RS02740_lanthipeptideNZ_CP028837.1 Lanthipeptides: C9432_RS15935_lanthipeptideNZ_CP033787.1 Lanthipeptides: EGX75_RS02740_lanthipeptideNZ_CP039296.1 Lanthipeptides: E7T02_RS02755_lanthipeptideNZ_CP045045.1 Lanthipeptides: F9293_RS12755_lanthipeptideNZ_CP075604.2 Lanthipeptides: KKP64_RS02155_lanthipeptideNZ_CP085289.1 Lanthipeptides: LIT95_RS07630_lanthipeptideNZ_CP085291.1 Lanthipeptides: LIT96_RS04335_lanthipeptideNZ_CP085297.1 Lanthipeptides: LIT97_RS14520_lanthipeptideNZ_CP086726.1 Lanthipeptides: LM507_RS03415_lanthipeptideNZ_CP091901.1 Lanthipeptides: L5I17_RS09010_lanthipeptideNZ_CP091905.1 Lanthipeptides: L5I20_RS14940_lanthipeptideNZ_CP091907.1 Lanthipeptides: L5I26_RS13265_lanthipeptideNZ_CP093957.1 Lanthipeptides: MPM64_RS01385_lanthipeptideNZ_CP116962.1 Lanthipeptides: PO880_RS13030_lanthipeptideNZ_JAASJP010000011.1 Lanthipeptides: HCH27_RS13275_lanthipeptideNZ_JAHZNN010000041.1 Lanthipeptides: K0X81_RS16410_lanthipeptideNZ_JAKTAU010000028.1 Lanthipeptides: MKK46_RS14535_lanthipeptideNZ_JALSCL010000035.1 Lanthipeptides: NEI30_RS13375_lanthipeptideNZ_JAQDOF010000024.1 Lanthipeptides: PGP79_RS14595_lanthipeptideNZ_JAQKZU010000014.1 Lanthipeptides: PMV60_RS12615_lanthipeptideNZ_KB932317.1 Lanthipeptides: Q95_RS09840_lanthipeptideNZ_KB932336.1 Lanthipeptides: Q9C_RS13350_lanthipeptideNZ_KB944697.1 Lanthipeptides: WO3_RS18030_lanthipeptideNZ_KB944708.1 Lanthipeptides: WO5_RS05650_lanthipeptideNZ_KB944753.1 Lanthipeptides: WO9_RS06460_lanthipeptideNZ_KB944762.1 Lanthipeptides: WOA_RS17470_lanthipeptideNZ_KB944819.1 Lanthipeptides: WOK_RS14355_lanthipeptideNZ_KB946767.1 Lanthipeptides: UK1_RS12990_lanthipeptideNZ_KB947483.1 Lanthipeptides: WUI_RS10440_lanthipeptideNZ_KZ845881.1 Lanthipeptides: EB41_RS04380_lanthipeptideNZ_NGMY01000001.1 Lanthipeptides: A5862_RS02370_lanthipeptide

Lanthipeptides: PO855_RS02215_lanthipeptide

GDVQAETTPACFTIGLGVGALFSAKFC

85.2%

NZ_CP011974.1and 2 others:

NZ_CP115914.1 Lanthipeptides: PGN40_RS02040_lanthipeptideNZ_MWSI01000006.1 Lanthipeptides: B1B01_RS20140_lanthipeptide

Lanthipeptides: BEH_RS02100_lanthipeptide

GDVQAETTPACFTIGLGVGALFSAKFC

GDVQAETTP CFTIGLGVGAL SA C

GDVQAETTPVCFTIGLGVGALVSAAGC

77.8%

NZ_JH791802.1and 2 others:

NZ_MIFM01000001.1 Lanthipeptides: BHL22_RS00410_lanthipeptideNZ_NINI01000009.1 Lanthipeptides: CEV12_RS07260_lanthipeptide

Lanthipeptides: IKS_RS03655_lanthipeptide

GDVQAETTPACFTIGLGVGALFSAKFC

GDVQAETTP CFT+GLGVG+L SA C

GDVQAETTPVCFTVGLGVGSLVSASVC

with 108 more sequence matches

Only the first 10 are displayed here.

74.1%

NZ_JH791802.1and 2 others:

NZ_MIFM01000001.1 Lanthipeptides: BHL22_RS00405_lanthipeptideNZ_NINI01000009.1 Lanthipeptides: CEV12_RS07255_lanthipeptide

Lanthipeptides: IKS_RS03660_lanthipeptide

GDVQAETTPACFTIGLGVGALFSAKFC

GDVQAETTP CFT+GLG+G+L SA C

GDVQAETTPVCFTVGLGIGSLVSASVC

71.4%

NZ_KB946334.1:

Lanthipeptides: UC7_RS10230_lanthipeptide

GDVQAETTPAC-FTIGLGVGALFSAKFC

GDVQ ETTP C FTIG+G+GAL S K+C

GDVQPETTPICGFTIGIGIGALASVKWC

71.4%

NZ_KB946334.1:

Lanthipeptides: UC7_RS10250_lanthipeptide

GDVQAETTPAC-FTIGLGVGALFSAKFC

GDVQ ETTP C FTIG+G+GAL S K+C

GDVQPETTPLCGFTIGIGIGALVSVKWC

70.0%

NZ_NVAW01000030.1and 1 other:

NZ_NVEP01000021.1 Lanthipeptides: COL17_RS24445_lanthipeptide

Lanthipeptides: COK11_RS25885_lanthipeptide

GDVQAETTPAC---FTIGLGVGALFSAKFC

GDV+ ETTPAC FTIGLG+GAL SA C

GDVKPETTPACLAGFTIGLGIGALASAAGC

66.7%

NZ_CP025701.1:

Lanthipeptides: C0569_RS26125_lanthipeptide

GDVQAETTPAC---FTIGLGVGALFSAKFC

GDV+ ETTPAC FT+GLG+GAL SA C

GDVKPETTPACLAGFTVGLGIGALASAAGC

63.0%

NZ_JACDUU010000003.1:

Lanthipeptides: HNQ85_RS08035_lanthipeptide

GDVQAETTPACFTIGLGVGALFSAKFC

GDVQ ET+PAC TIG+G+G S FC

GDVQPETSPACVTIGIGIGIGISKLFC

59.3%

NZ_JAOVZP010000016.1and 3 others:

NZ_NHVL01000036.1 Lanthipeptides: CEU70_RS27720_lanthipeptideNZ_NTYE01000081.1 Lanthipeptides: CN490_RS28165_lanthipeptideNZ_NVMN01000027.1 Lanthipeptides: CON30_RS23205_lanthipeptide

Lanthipeptides: OF830_RS26725_lanthipeptide

GDVQAETTPACFTIGLGVGALFSAKFC

DVQ ETTPAC T L G +FS K+C

SDVQPETTPACVT-ALTTGIIFSIKWC

58.6%

NZ_JAOVZP010000016.1and 3 others:

NZ_NHVL01000036.1 Lanthipeptides: CEU70_RS27725_lanthipeptideNZ_NTYE01000081.1 Lanthipeptides: CN490_RS28170_lanthipeptideNZ_NVMN01000027.1 Lanthipeptides: CON30_RS23200_lanthipeptide

Lanthipeptides: OF830_RS26730_lanthipeptide

GDVQAETTPAC---FTIGLGVGALFSAKFC

DVQ ETTPAC FTIG V +FS + C

SDVQPETTPACAVAFTIGATV--IFSVRNC

57.1%

NZ_JANFNS010000003.1:

Lanthipeptides: NOM90_RS11325_lanthipeptide

DVQAETTPAC-FTIGLGVGALFSAKFC

DVQ ETTP C F +G+G+GA+ SA C

DVQPETTPVCGFFVGVGIGAIISATAC

55.6%

NZ_JACSPU010000002.1:

Lanthipeptides: H9630_RS06775_lanthipeptide

GDVQAETTPACFTIGLGVGALFSAKFC

DV ETTPAC G LFS KFC

SDVAPETTPAC-VAAFATGLLFSIKFC

MIBiG 4.0 matches for C7I32_RS15475

27.0%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

TTPACFTIGLGVGAL-------FSAKFC

T PA + LG+ A+ SA FC

TDPAVTGLILGIVAIQAGVAVGVSAAFC

11.8%

BGC0000535.4 (ADJ56352.1):

Lanthipeptide: nisin A

TPACFT

TP C T

TPGCKT

7.8%

BGC0002120.3 (NQE92413.1):

Lanthipeptide: nocathioamide A

PACFTIG

PAC T+

PACHTLS

C7I32_RS15480

Leader:

MENLSVVPSFEELSVEEMEAIQGS

Core:

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

Core with dehydrations:

GDVQAEDhbDhbPVCysAVAADhbAAADhaDhaAACysGWVGGGIFDhbGVDhbVVVDhaLKHCys

antiSMASH-DB 4.0 matches for C7I32_RS15480

100.0%

NZ_AP026721.1and 34 others:

NZ_CP015883.1 Lanthipeptides: A6B47_RS00880_lanthipeptideNZ_CP028286.1 Lanthipeptides: CEQ02_RS16120_lanthipeptideNZ_CP028721.1 Lanthipeptides: C7I32_RS15480_lanthipeptideNZ_CP028835.1 Lanthipeptides: C9432_RS02735_lanthipeptideNZ_CP028837.1 Lanthipeptides: C9432_RS15930_lanthipeptideNZ_CP033787.1 Lanthipeptides: EGX75_RS02745_lanthipeptideNZ_CP039296.1 Lanthipeptides: E7T02_RS02750_lanthipeptideNZ_CP045045.1 Lanthipeptides: F9293_RS12760_lanthipeptideNZ_CP075604.2 Lanthipeptides: KKP64_RS02150_lanthipeptideNZ_CP085289.1 Lanthipeptides: LIT95_RS07625_lanthipeptideNZ_CP085291.1 Lanthipeptides: LIT96_RS04340_lanthipeptideNZ_CP085297.1 Lanthipeptides: LIT97_RS14515_lanthipeptideNZ_CP086726.1 Lanthipeptides: LM507_RS03420_lanthipeptideNZ_CP091901.1 Lanthipeptides: L5I17_RS09015_lanthipeptideNZ_CP091905.1 Lanthipeptides: L5I20_RS14935_lanthipeptideNZ_CP091907.1 Lanthipeptides: L5I26_RS13260_lanthipeptideNZ_CP093957.1 Lanthipeptides: MPM64_RS01390_lanthipeptideNZ_CP116962.1 Lanthipeptides: PO880_RS13035_lanthipeptideNZ_JAASJP010000011.1 Lanthipeptides: HCH27_RS13280_lanthipeptideNZ_JAHZNN010000041.1 Lanthipeptides: K0X81_RS16405_lanthipeptideNZ_JAKTAU010000028.1 Lanthipeptides: MKK46_RS14540_lanthipeptideNZ_JALSCL010000035.1 Lanthipeptides: NEI30_RS13380_lanthipeptideNZ_JAQDOF010000024.1 Lanthipeptides: PGP79_RS14600_lanthipeptideNZ_JAQKZU010000014.1 Lanthipeptides: PMV60_RS12620_lanthipeptideNZ_KB932317.1 Lanthipeptides: Q95_RS09835_lanthipeptideNZ_KB932336.1 Lanthipeptides: Q9C_RS13355_lanthipeptideNZ_KB944697.1 Lanthipeptides: WO3_RS18035_lanthipeptideNZ_KB944708.1 Lanthipeptides: WO5_RS05645_lanthipeptideNZ_KB944753.1 Lanthipeptides: WO9_RS06455_lanthipeptideNZ_KB944762.1 Lanthipeptides: WOA_RS17465_lanthipeptideNZ_KB944819.1 Lanthipeptides: WOK_RS14360_lanthipeptideNZ_KB946767.1 Lanthipeptides: UK1_RS12995_lanthipeptideNZ_KB947483.1 Lanthipeptides: WUI_RS10435_lanthipeptideNZ_KZ845881.1 Lanthipeptides: EB41_RS04385_lanthipeptide

Lanthipeptides: PO855_RS02210_lanthipeptide

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

93.2%

NZ_CP011974.1and 2 others:

NZ_CP115914.1 Lanthipeptides: PGN40_RS02045_lanthipeptideNZ_MWSI01000006.1 Lanthipeptides: B1B01_RS20135_lanthipeptide

Lanthipeptides: BEH_RS02105_lanthipeptide

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

GDVQAETTPVCA+AATAAASSAACG+VGGGIFTGVTVVVSLK C

GDVQAETTPVCAIAATAAASSAACGYVGGGIFTGVTVVVSLKSC

90.9%

NZ_CP011974.1and 2 others:

NZ_CP115914.1 Lanthipeptides: PGN40_RS02050_lanthipeptideNZ_MWSI01000006.1 Lanthipeptides: B1B01_RS20130_lanthipeptide

Lanthipeptides: BEH_RS02110_lanthipeptide

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

GDVQAETTPVCA+AATAAASSAACG+VGGGIFTGVTVVV+LK C

GDVQAETTPVCAIAATAAASSAACGYVGGGIFTGVTVVVTLKSC

with 107 more sequence matches

Only the first 10 are displayed here.

86.4%

NZ_JH791802.1and 5 others:

NZ_MIFM01000001.1 Lanthipeptides: BHL22_RS00420_lanthipeptideNZ_MIFM01000001.1 Lanthipeptides: BHL22_RS00415_lanthipeptideNZ_NINI01000009.1 Lanthipeptides: CEV12_RS07275_lanthipeptideNZ_NINI01000009.1 Lanthipeptides: CEV12_RS07270_lanthipeptideNZ_NINI01000009.1 Lanthipeptides: CEV12_RS07265_lanthipeptide

Lanthipeptides: IKS_RS30065_lanthipeptide

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

GDVQAETTPVCA+AAT AASSAACGWVGGGI TGVTVV++LK C

GDVQAETTPVCAIAATTAASSAACGWVGGGIATGVTVVITLKSC

84.1%

NZ_CP025701.1:

Lanthipeptides: C0569_RS26130_lanthipeptide

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

GDVQAETTPVCA+AATAAASS C GGGI TGVTVVVSLKHC

GDVQAETTPVCAIAATAAASSGICAATGGGIATGVTVVVSLKHC

81.8%

NZ_NVAW01000030.1and 1 other:

NZ_NVEP01000021.1 Lanthipeptides: COL17_RS24440_lanthipeptide

Lanthipeptides: COK11_RS25880_lanthipeptide

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

GDVQAETTPVCAVAATAAASS C G GI TGVTVVVSLK C

GDVQAETTPVCAVAATAAASSGVCAATGAGIATGVTVVVSLKSC

77.3%

NZ_MIFM01000001.1and 1 other:

NZ_NINI01000009.1 Lanthipeptides: CEV12_RS07280_lanthipeptide

Lanthipeptides: BHL22_RS00425_lanthipeptide

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

GDVQAETTPVCAV+ SSAACGWV GGI TGVTVVV+LK C

GDVQAETTPVCAVSVATMTSSAACGWVAGGIATGVTVVVTLKSC

72.7%

NZ_CP062165.1and 5 others:

NZ_CP062165.1 Lanthipeptides: JNUCC31_RS17165_lanthipeptideNZ_QICW01000005.1 Lanthipeptides: DEU73_RS14625_lanthipeptideNZ_QICW01000005.1 Lanthipeptides: DEU73_RS14625_lanthipeptideNZ_QLLI01000007.1 Lanthipeptides: DET54_RS17330_lanthipeptideNZ_QLLI01000007.1 Lanthipeptides: DET54_RS17330_lanthipeptide

Lanthipeptides: JNUCC31_RS17165_lanthipeptide

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

GDVQ ETTPVCAVAAT AASSA C VGGGI GVT+V+++K C

GDVQPETTPVCAVAATVAASSATCAAVGGGIAVGVTIVLTIKSC

72.7%

NZ_JANFNS010000003.1:

Lanthipeptides: NOM90_RS11330_lanthipeptide

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

DVQ ETTPVCAVAAT AASSA C VGGG+ GVTVV++LK C

ADVQPETTPVCAVAATVAASSATCAAVGGGVAVGVTVVLTLKTC

70.5%

NZ_KB946334.1and 1 other:

NZ_KB946334.1 Lanthipeptides: UC7_RS10235_lanthipeptide

Lanthipeptides: UC7_RS10245_lanthipeptide

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

GDVQAETTPVCA++AT AASSAAC VG GI TG+T+V++ K C

GDVQAETTPVCAISATVAASSAACAGVGAGIGTGITIVLTFKRC

68.2%

NZ_KB946334.1:

Lanthipeptides: UC7_RS10240_lanthipeptide

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

GDVQ ETTPVCA++AT AASSAAC VG GI TG+T+V++ K C

GDVQVETTPVCAISATVAASSAACAGVGAGIGTGITIVLTFKRC

68.2%

NZ_LN831278.1:

Lanthipeptides: BN1360_RS08835_lanthipeptide

DVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

DVQ ETTP+CAVAAT AASSA C VGGGI GVT+V+++K C

DVQPETTPICAVAATVAASSATCAAVGGGIAVGVTIVLTIKSC

65.9%

NC_014098.1:

Lanthipeptides: BTUS_RS14190_lanthipeptide

GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKHC

GDVQAETTP+C AAT ASSAAC VG GI GVT+V+++K C

GDVQAETTPICYTAATVTASSAACAGVGAGIVAGVTIVLTIKRC

allorf_32905_33036

Leader:

MVGLNEERETKLKRRRPVEQSETNYS

Core:

SFRVWPCSWYKKLFVFK

Core with dehydrations:

DhaFRVWPCysDhaWYKKLFVFK

antiSMASH-DB 4.0 matches for allorf_32905_33036

100.0%

NZ_CP028721.1:

Lanthipeptides: allorf_32905_33036_lanthipeptide

SFRVWPCSWYKKLFVFK

94.1%

NZ_JAQKZU010000014.1:

Lanthipeptides: allorf_35422_35553_lanthipeptide

SFRVWPCSWYKKLFVFK

SFRV PCSWYKKLFVFK

SFRVCPCSWYKKLFVFK

31.6%

NZ_CP086142.1:

Lanthipeptides: allorf_039242_039433_lanthipeptide

FRVWPCSWYKKLFV

F W CS+ ++FV

FTSWNCSYKLQIFV

with 3 more sequence matches

17.2%

NC_014098.1:

Lanthipeptides: allorf_2904154_2904300_lanthipeptide

PCSWYKKLFVF

PCS + +FV

PCSGFSAVFVL

15.0%

NZ_CP070496.1:

Lanthipeptides: allorf_3787373_3787519_lanthipeptide

SFRVWPCSW

S +VW CSW

SIQVWQCSW

8.6%

NZ_CP101913.1:

Lanthipeptides: allorf_1841460_1841675_lanthipeptide

SFRVWPCS

+FR++PCS

TFRLFPCS

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

Binding sites found:

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.60 out of 30.25

Confidence: medium

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 24.29 out of 29.38

Confidence: medium

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 26.49 out of 32.93

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 24.10 out of 24.78

Confidence: strong

Additional weak hits (5):

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 19.86 out of 30.22

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 21.02 out of 29.65

Confidence: weak

LuxO

Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 20.68 out of 26.12

Confidence: weak

NrdR

Description: Represses ribonucleotide reductase encoding genes
Species: Streptomyces coelicolor
Score: 19.13 out of 27.18

Confidence: weak

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 16.18 out of 19.52

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

C7I32_RS16360 - Class II

Cleavage pHMM score: -6.20

RODEO score: 0

Monoisotopic mass: 6346.1 Da

Molecular weight: 6350.3 Da

Number of bridges: 5

Alternative weights: (assuming N unmodified Ser/Thr residues); 6368.3 Da N = 1; 6386.3 Da N = 2; 6404.3 Da N = 3; 6422.3 Da N = 4; 6440.4 Da N = 5; 6458.4 Da N = 6

C7I32_RS15475 - Class II

Cleavage pHMM score: 2.00

RODEO score: 0

Monoisotopic mass: 2630.3 Da

Molecular weight: 2632.0 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 2650.0 Da N = 1; 2668.0 Da N = 2

C7I32_RS15480 - Class II

Cleavage pHMM score: 2.00

RODEO score: 0

Monoisotopic mass: 4017.0 Da

Molecular weight: 4019.5 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 4037.6 Da N = 1; 4055.6 Da N = 2; 4073.6 Da N = 3; 4091.6 Da N = 4; 4109.6 Da N = 5

allorf_32905_33036 - Class II

Cleavage pHMM score: -4.10

RODEO score: 0

Monoisotopic mass: 2184.2 Da

Molecular weight: 2185.6 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2203.6 Da N = 1

TFBS definitions

Regulator	Description
ColR	Phenol-responsive regulator
FuR variant 1	Ferric Uptake Regulator
LexA variant 2	Repressor of DNA damage response
LexA variant 3	Repressor of DNA damage response