GCF_003111765.1 - 2 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP027862.1 (Actinomyces sp. Z16)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	lanthipeptide-class-ii	88,439	116,261
Region 2	terpene-precursor	2,039,357	2,060,502

NZ_CP027862.1 - Region 1 - lanthipeptide-class-ii

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Location: 88,439 - 116,261 nt. (total: 27,823 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

C3B71_RS15670: crotonyl-CoA reductase / alcohol dehydrogenase

smcogs: SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase

Lyases: cyclase

C3B71_RS00445: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

C3B71_RS00455: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000520.5	0.62	ribosomal	lacticin 3147 A1, lacticin 3147 A2	Lactococcus lactis
BGC0001229.4	0.62	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000517.4	0.59	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0002110.3	0.57	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0000555.3	0.57	ribosomal	staphylococcin C55 α, staphylococcin C55 β	Staphylococcus aureus
BGC0001555.4	0.51	ribosomal	colicin V	Escherichia coli chi7122
BGC0000528.5	0.51	ribosomal	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001311.5	0.51	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0001210.5	0.50	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0002698.2	0.50	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000520.5	0.62	ribosomal	lacticin 3147 A1, lacticin 3147 A2	Lactococcus lactis
BGC0001229.4	0.62	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000517.4	0.59	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0002110.3	0.57	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0000555.3	0.57	ribosomal	staphylococcin C55 α, staphylococcin C55 β	Staphylococcus aureus
BGC0001555.4	0.51	ribosomal	colicin V	Escherichia coli chi7122
BGC0000528.5	0.51	ribosomal	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001311.5	0.51	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0001210.5	0.50	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0002698.2	0.50	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for C3B71_RS00445

C3B71_RS00410

Leader:

MPTPRAAGWSLLLVGIALSALAA

Core:

CTHLAWLWIIAIVVLVASIGTLAVAFVSDADGPGDGRRR

Core with dehydrations:

CysDhbHLAWLWIIAIVVLVADhaIGDhbLAVAFVDhaDADGPGDGRRR

antiSMASH-DB 4.0 matches for C3B71_RS00410

100.0%

NZ_CP027862.1:

Lanthipeptides: C3B71_RS00410_lanthipeptide

CTHLAWLWIIAIVVLVASIGTLAVAFVSDADGPGDGRRR

C3B71_RS16245

Leader:

MLAPHDLTGA

Core:

VVTADALHTDRHSAADTRPGRRLCAGRQGQPARPESEAEG

Core with dehydrations:

VVDhbADALHDhbDRHDhaAADDhbRPGRRLCysAGRQGQPARPEDhaEAEG

antiSMASH-DB 4.0 matches for C3B71_RS16245

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: C3B71_RS16245_lanthipeptide

Lanthipeptides: C3B71_RS16245_lanthipeptide

VVTADALHTDRHSAADTRPGRRLCAGRQGQPARPESEAEG

25.0%

NZ_CP013141.1:

Lanthipeptides: allorf_5320283_5320453_lanthipeptide

PGRRLCAGRQGQPARPE

PG+ GR GQPAR E

PGQGAQGGRPGQPARAE

17.5%

NZ_VBSN01000041.1:

Lanthipeptides: FEM33_RS15105_lanthipeptide

TRPGRRLCAGRQG

T PG+ CAG G

TAPGQSCCAGSNG

allorf_0094367_0094588

Leader:

MCIGGCGLSARVIGANVVLQTGVLGG

Core:

CLLPAFAVWTAVPCLDRVSLFGPPLCAAWAVQTDARGPNRRGRSKPR

Core with dehydrations:

CysLLPAFAVWDhbAVPCysLDRVDhaLFGPPLCysAAWAVQDhbDARGPNRRGRDhaKPR

antiSMASH-DB 4.0 matches for allorf_0094367_0094588

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0094367_0094588_lanthipeptide

Lanthipeptides: allorf_0094367_0094588_lanthipeptide

CLLPAFAVWTAVPCLDRVSLFGPPLCAAWAVQTDARGPNRRGRSKPR

21.6%

NZ_CP027306.1:

Lanthipeptides: allorf_8952890_8953126_lanthipeptide

SLFGPPLCAAWAVQT--DARGPNR

L GPPL A W ++ D RG R

GLLGPPLSALWQRESLFDERGLFR

11.5%

NZ_KB900614.1:

Lanthipeptides: allorf_2973093_2973293_lanthipeptide

LLPAFAVWTAVPCLDR

L+PAF+++ +P L

LIPAFSIFMTMPSLGH

MIBiG 4.0 matches for allorf_0094367_0094588

8.5%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

AAWAVQTDARGPN

W T PN

GGWCTLTKECQPN

allorf_0097945_0098112

Leader:

MESQAEVTWIEEVGEQSFDTDVFGA

Core:

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

Core with dehydrations:

CysDhaDhbNDhbFDhaLDhaDYWGNRGYWCysDhbLDhbHECysMDhaWCysK

antiSMASH-DB 4.0 matches for allorf_0097945_0098112

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide

Lanthipeptides: allorf_0097945_0098112_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

90.0%

NZ_QGEE01000020.1and 5 others:

NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06160_lanthipeptideNZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptideNZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptideNZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptideNZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide

Lanthipeptides: DKP74_RS06160_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

CSTNTFSLSDYWGNRG WCTL+HECM+WCK

CSTNTFSLSDYWGNRGNWCTLSHECMAWCK

86.7%

NZ_BLIS01000009.1and 7 others:

NZ_BLIS01000009.1 Lanthipeptides: GVO03_RS04820_lanthipeptideNZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptideNZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptideNZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptideNZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptideNZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptideNZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide

Lanthipeptides: GVO03_RS04820_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLSDYWGN+G WCTLTHECM+WCK

CTTNTFSLSDYWGNKGNWCTLTHECMNWCK

with 106 more sequence matches

Only the first 10 are displayed here.

86.7%

NZ_CACZYW010000004.1and 1 other:

NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide

Lanthipeptides: HUF10_RS02825_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

CSTNTFSLSDYWGN G WCTL+HECM+WCK

CSTNTFSLSDYWGNNGNWCTLSHECMAWCK

86.7%

NZ_CP034414.1and 1 other:

NZ_CP034414.1 Lanthipeptides: EI692_RS18440_lanthipeptide

Lanthipeptides: EI692_RS18440_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

CSTNTFSLSDYWGN+G WCT++HECMSWCK

CSTNTFSLSDYWGNKGGWCTISHECMSWCK

86.7%

NZ_CP051884.1and 2 others:

NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptideNZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide

Lanthipeptides: HGK68_RS15125_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

CSTNTFSLSDYWGN G+ CT+THECMSWCK

CSTNTFSLSDYWGNNGWLCTITHECMSWCK

86.7%

NZ_CP061868.1and 1 other:

NZ_CP061868.1 Lanthipeptides: IE339_RS06330_lanthipeptide

Lanthipeptides: IE339_RS06330_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLSDYWGN+G WCT THECMSWCK

CTTNTFSLSDYWGNKGGWCTATHECMSWCK

86.7%

NZ_FMPI01000012.1and 1 other:

NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08305_lanthipeptide

Lanthipeptides: BJR39_RS08305_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

CSTNTFSLSDYWGN G WCT +HECMSWCK

CSTNTFSLSDYWGNNGNWCTASHECMSWCK

86.7%

NZ_PCGR01000003.1and 1 other:

NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09620_lanthipeptide

Lanthipeptides: CQS04_RS09620_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLSDYWGN G WCT THECMSWCK

CTTNTFSLSDYWGNNGNWCTATHECMSWCK

83.3%

NZ_AP026714.1and 21 others:

NZ_AP026714.1 Lanthipeptides: PO853_RS06515_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide

Lanthipeptides: PO853_RS06515_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLSDYWGN+G WCT THECM WCK

CTTNTFSLSDYWGNKGNWCTATHECMGWCK

83.3%

NZ_MIFN01000022.1and 1 other:

NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15350_lanthipeptide

Lanthipeptides: BHL26_RS15350_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLSDYWGN G WC+L+HECMSWCK

CTTNTFSLSDYWGNDGSWCSLSHECMSWCK

83.3%

NZ_NUIO01000031.1and 1 other:

NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23160_lanthipeptide

Lanthipeptides: CN977_RS23160_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLSDYWGN G WCT THEC+SWCK

CTTNTFSLSDYWGNDGSWCTATHECLSWCK

80.0%

NZ_FNHR01000005.1and 1 other:

NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05590_lanthipeptide

Lanthipeptides: BLQ37_RS05590_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

CSTNTFSLSDY GN G WCT++HECM+WCK

CSTNTFSLSDYMGNNGNWCTISHECMAWCK

MIBiG 4.0 matches for allorf_0097945_0098112

63.3%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLS+ GN G WCTLT EC C

CTTNTFSLSNALGNNGGWCTLTKECQPNCN

40.0%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

FSLSDYWGNRGYWCTLTHECMSWC

+++S GN+G +CTLT ECM C

YNISCRLGNKGAYCTLTVECMPSC

15.4%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTLTHECMSWC

CTL+ EC C

CTLSKECQPNC

allorf_0098227_0098397

Leader:

MNNLELGKYLESDMIAVTEEDVEGG

Core:

ATPAVATAALLAVGGFISHNTCPTTVCTRAC

Core with dehydrations:

ADhbPAVADhbAALLAVGGFIDhaHNDhbCysPDhbDhbVCysDhbRACys

antiSMASH-DB 4.0 matches for allorf_0098227_0098397

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: C3B71_RS16030_lanthipeptide

Lanthipeptides: C3B71_RS16030_lanthipeptide

ATPAVATAALLAVGGFISHNTCPTTVCTRAC

67.7%

NZ_NUIO01000031.1and 1 other:

NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23165_lanthipeptide

Lanthipeptides: CN977_RS23165_lanthipeptide

TPAVATAALLAVGGFISHNTCPTTVCTRAC

TP V+ AL AV G+IS NTCPTT CTRAC

TPTVS-IALTAVSGYISSNTCPTTACTRAC

60.6%

NZ_LR134317.1and 1 other:

NZ_LR134317.1 Lanthipeptides: EL136_RS01690_lanthipeptide

Lanthipeptides: EL136_RS01690_lanthipeptide

ATPAVATAALLAVGGFISHNTCPTTVCTRAC

ATP + A++ AV FIS NTCPTT CTRAC

ATPWLVKASV-AVTAFISANTCPTTSCTRAC

with 82 more sequence matches

Only the first 10 are displayed here.

58.1%

NZ_CP034414.1and 1 other:

NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide

Lanthipeptides: EI692_RS18435_lanthipeptide

TPAVATAALLAVGGFISHNTCPTTVCTRAC

TPA++ + V GFIS NTCP+T CTRAC

TPAIS----ILVSGFISTNTCPSTACTRAC

56.2%

NZ_CACZYW010000004.1and 3 others:

NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptideNZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptideNZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide

Lanthipeptides: HUF10_RS02820_lanthipeptide

TPAV-ATAALLAVGGFISHNTCPTTVCTRAC

TPA AT ++AV ++S TCPTT CTRAC

TPATPATPVIVAVSAYVSDKTCPTTACTRAC

54.8%

NZ_AP026714.1and 21 others:

NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide

Lanthipeptides: PO853_RS06520_lanthipeptide

ATPAVATAALLAVGGFISHNTCPTTVCTRAC

TP + +AV G+IS TCPT+VCTRAC

GTPTITIPISIAVSGWISDKTCPTSVCTRAC

54.8%

NZ_CP016767.1and 3 others:

NZ_CP016767.1 Lanthipeptides: BCV50_RS13415_lanthipeptideNZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptideNZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide

Lanthipeptides: BCV50_RS13415_lanthipeptide

TAALLAVGGFISHNTCPTTVCTRAC

T AL + G+IS NTCPTT CTRAC

TPALSVITGYISSNTCPTTACTRAC

54.8%

NZ_CP061868.1and 1 other:

NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide

Lanthipeptides: IE339_RS06335_lanthipeptide

TAALLAVGGFISHNTCPTTVCTRAC

T + AV G+IS NTCPTT CTRAC

TIVITAVTGYISTNTCPTTSCTRAC

54.8%

NZ_JALAPU010000003.1and 7 others:

NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07925_lanthipeptideNZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00585_lanthipeptideNZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00585_lanthipeptideNZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17010_lanthipeptideNZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17010_lanthipeptideNZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04640_lanthipeptideNZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04640_lanthipeptide

Lanthipeptides: MOD17_RS07925_lanthipeptide

TAALLAVGGFISHNTCPTTVCTRAC

T AL V +IS NTCPTT CTRAC

TPALSVVTAYISSNTCPTTACTRAC

54.8%

NZ_QGEE01000020.1and 3 others:

NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06165_lanthipeptideNZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptideNZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptide

Lanthipeptides: DKP74_RS06165_lanthipeptide

TPAVATAALLAVGGFISHNTCPTTVCTRAC

TP + +A++ V GF+S +TCPTT CTRAC

TPVIGYSAVI-VSGFVSSHTCPTTACTRAC

54.5%

NZ_MIFN01000022.1and 1 other:

NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide

Lanthipeptides: BHL26_RS15355_lanthipeptide

TAALLAVGGFISHNTCPTTVCTRAC

T AL AV G+IS NTCP+T CTRAC

TGALTAVSGYISSNTCPSTACTRAC

51.6%

NZ_PCGR01000003.1and 1 other:

NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide

Lanthipeptides: CQS04_RS09625_lanthipeptide

AVATAALLAVGGFISHNTCPTTVCTRAC

A T + A+ G+IS N+CPTT CTRAC

ATPTIVITAITGYISANSCPTTACTRAC

46.9%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

TPAVATAALLAVGGFISHNTCPTTVCTRAC

TPA T + VG IS CPTT CT C

TPATPT---IVVG--ISVGLCPTTKCTSKC

MIBiG 4.0 matches for allorf_0098227_0098397

37.8%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

VATAALLAVGGFISHNTCPTTVCTRAC

VA A +AVG +S CPTT CT C

VAIQAGVAVG--VSAAFCPTTKCTSRC

22.6%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

CPTTVCTRAC

CPTT CT C

CPTTKCTSKC

allorf_0109463_0109555

Leader:

MWWWGGAGDVGGG

Core:

LVADGELVVSGGCGARV

Core with dehydrations:

LVADGELVVDhaGGCysGARV

antiSMASH-DB 4.0 matches for allorf_0109463_0109555

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0109463_0109555_lanthipeptide

Lanthipeptides: allorf_0109463_0109555_lanthipeptide

LVADGELVVSGGCGARV

15.0%

NZ_CP114040.1:

Lanthipeptides: O0S08_RS10560_lanthipeptide

ELVVSGGCGAR

E+ SGGCG++

EVHASGGCGSQ

allorf_0109479_0109712

Leader:

MLAMWVVVWWRMVSWSCLVAVGPEFEWAACALRELARAFVSSLALLGA

Core:

SSRSRVVDVGACGRAGCVLSEDWCAQSGA

Core with dehydrations:

DhaDhaRDhaRVVDVGACysGRAGCysVLDhaEDWCysAQDhaGA

antiSMASH-DB 4.0 matches for allorf_0109479_0109712

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0109479_0109712_lanthipeptide

Lanthipeptides: allorf_0109479_0109712_lanthipeptide

SSRSRVVDVGACGRAGCVLSEDWCAQSGA

34.5%

NZ_AP014940.1:

Lanthipeptides: allorf_3267938_3268081_lanthipeptide

ACGRAGCVLSEDWCAQSGA

AC RA +S CAQ GA

ACNRAARSVSRLPCAQRGA

21.2%

NZ_CP110813.1:

Lanthipeptides: allorf_5693634_5693777_lanthipeptide

RAGCVLSEDW

RAGCV S+ W

RAGCVESDRW

allorf_0109556_0109681

Leader:

MGCVRPSGARSRLRELACA

Core:

VGSVVPEPGCRRGCLWAGRLCA

Core with dehydrations:

VGDhaVVPEPGCysRRGCysLWAGRLCysA

antiSMASH-DB 4.0 matches for allorf_0109556_0109681

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0109556_0109681_lanthipeptide

Lanthipeptides: allorf_0109556_0109681_lanthipeptide

VGSVVPEPGCRRGCLWAGRLCA

36.4%

NZ_CP106798.1:

Lanthipeptides: allorf_8193611_8193688_lanthipeptide

VGSVVPEPGCRRGC

V SV PG R GC

VTSVADMPGTRSGC

24.0%

NZ_GL545262.1:

Lanthipeptides: HMPREF0798_RS11845_lanthipeptide

VGSVVPEPGCRRGCLWA

+ S+ PEP R W+

IQSMTPEPSVTRILTWS

with 2 more sequence matches

16.7%

NZ_QJTF01000024.1:

Lanthipeptides: allorf_35736_35903_lanthipeptide

PGCRRGCLWAGR

GC GC AGR

DGCSTGCTEAGR

14.3%

NC_014718.1:

Lanthipeptides: RBRH_RS14080_lanthipeptide

SVVPEPGCRR

+V P+PG R+

AVTPQPGTRQ

allorf_0109701_0109913

Leader:

MDRCSPDGPLFPRWTAVAAGYSGPTGRGRSNGA

Core:

WAVQRGVGGPTGPVQDPLAPFDCRQPGPRHRGNALRA

Core with dehydrations:

WAVQRGVGGPDhbGPVQDPLAPFDCysRQPGPRHRGNALRA

antiSMASH-DB 4.0 matches for allorf_0109701_0109913

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0109701_0109913_lanthipeptide

Lanthipeptides: allorf_0109701_0109913_lanthipeptide

WAVQRGVGGPTGPVQDPLAPFDCRQPGPRHRGNALRA

35.1%

NZ_CP072827.1:

Lanthipeptides: allorf_1271443_1271583_lanthipeptide

GGPTGP---VQDPLAPFDCRQPGPRHRGNA

GGP P V LA ++CR H GNA

GGPEHPSLRVGGALASYECRNRLCSHAGNA

29.7%

NZ_FNBR01000006.1and 1 other:

NZ_FUYT01000011.1 Lanthipeptides: allorf_180567_180686_lanthipeptide

Lanthipeptides: allorf_233241_233360_lanthipeptide

LAPFD-CRQPGPRHRGNALR

L P D CR PG R NA+R

LTPADSCRAPGYGTRANAMR

with 2 more sequence matches

26.1%

NZ_BNBI01000017.1:

Lanthipeptides: IE316_RS35725_lanthipeptide

WAVQRGVGG--PTGPVQDPLAPFDCRQPGPRHRGNA

W V+R +++PL D R+P PR R N+

WVVERTFAWLYQFKRLRNPLR--DTRRPPPRTRSNS

18.9%

NZ_NNBP01000005.1:

Lassopeptides: CG747_RS46885_lassopeptide

GGPTGPVQDPLAPFDC

GG V++ AP+DC

GGDDTGVENKRAPYDC

MIBiG 4.0 matches for allorf_0109701_0109913

13.5%

BGC0002150.2 (MBO0654592.1):

Lasso peptide: triculamin

QPGPRHRGNALRA

+PG RG +R

KPGDGIRGKGVRG

Lanthipeptide(s) for C3B71_RS00455

C3B71_RS16245

Leader:

MLAPHDLTGA

Core:

VVTADALHTDRHSAADTRPGRRLCAGRQGQPARPESEAEG

Core with dehydrations:

VVDhbADALHDhbDRHDhaAADDhbRPGRRLCysAGRQGQPARPEDhaEAEG

antiSMASH-DB 4.0 matches for C3B71_RS16245

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: C3B71_RS16245_lanthipeptide

Lanthipeptides: C3B71_RS16245_lanthipeptide

VVTADALHTDRHSAADTRPGRRLCAGRQGQPARPESEAEG

25.0%

NZ_CP013141.1:

Lanthipeptides: allorf_5320283_5320453_lanthipeptide

PGRRLCAGRQGQPARPE

PG+ GR GQPAR E

PGQGAQGGRPGQPARAE

17.5%

NZ_VBSN01000041.1:

Lanthipeptides: FEM33_RS15105_lanthipeptide

TRPGRRLCAGRQG

T PG+ CAG G

TAPGQSCCAGSNG

allorf_0094367_0094588

Leader:

MCIGGCGLSARVIGANVVLQTGVLGG

Core:

CLLPAFAVWTAVPCLDRVSLFGPPLCAAWAVQTDARGPNRRGRSKPR

Core with dehydrations:

CysLLPAFAVWDhbAVPCysLDRVDhaLFGPPLCysAAWAVQDhbDARGPNRRGRDhaKPR

antiSMASH-DB 4.0 matches for allorf_0094367_0094588

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0094367_0094588_lanthipeptide

Lanthipeptides: allorf_0094367_0094588_lanthipeptide

CLLPAFAVWTAVPCLDRVSLFGPPLCAAWAVQTDARGPNRRGRSKPR

21.6%

NZ_CP027306.1:

Lanthipeptides: allorf_8952890_8953126_lanthipeptide

SLFGPPLCAAWAVQT--DARGPNR

L GPPL A W ++ D RG R

GLLGPPLSALWQRESLFDERGLFR

11.5%

NZ_KB900614.1:

Lanthipeptides: allorf_2973093_2973293_lanthipeptide

LLPAFAVWTAVPCLDR

L+PAF+++ +P L

LIPAFSIFMTMPSLGH

MIBiG 4.0 matches for allorf_0094367_0094588

8.5%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

AAWAVQTDARGPN

W T PN

GGWCTLTKECQPN

allorf_0097945_0098112

Leader:

MESQAEVTWIEEVGEQSFDTDVFGA

Core:

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

Core with dehydrations:

CysDhaDhbNDhbFDhaLDhaDYWGNRGYWCysDhbLDhbHECysMDhaWCysK

antiSMASH-DB 4.0 matches for allorf_0097945_0098112

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide

Lanthipeptides: allorf_0097945_0098112_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

90.0%

NZ_QGEE01000020.1and 5 others:

Lanthipeptides: DKP74_RS06160_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

CSTNTFSLSDYWGNRG WCTL+HECM+WCK

CSTNTFSLSDYWGNRGNWCTLSHECMAWCK

86.7%

NZ_BLIS01000009.1and 7 others:

Lanthipeptides: GVO03_RS04820_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLSDYWGN+G WCTLTHECM+WCK

CTTNTFSLSDYWGNKGNWCTLTHECMNWCK

with 106 more sequence matches

Only the first 10 are displayed here.

86.7%

NZ_CACZYW010000004.1and 1 other:

NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide

Lanthipeptides: HUF10_RS02825_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

CSTNTFSLSDYWGN G WCTL+HECM+WCK

CSTNTFSLSDYWGNNGNWCTLSHECMAWCK

86.7%

NZ_CP034414.1and 1 other:

NZ_CP034414.1 Lanthipeptides: EI692_RS18440_lanthipeptide

Lanthipeptides: EI692_RS18440_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

CSTNTFSLSDYWGN+G WCT++HECMSWCK

CSTNTFSLSDYWGNKGGWCTISHECMSWCK

86.7%

NZ_CP051884.1and 2 others:

NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptideNZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide

Lanthipeptides: HGK68_RS15125_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

CSTNTFSLSDYWGN G+ CT+THECMSWCK

CSTNTFSLSDYWGNNGWLCTITHECMSWCK

86.7%

NZ_CP061868.1and 1 other:

NZ_CP061868.1 Lanthipeptides: IE339_RS06330_lanthipeptide

Lanthipeptides: IE339_RS06330_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLSDYWGN+G WCT THECMSWCK

CTTNTFSLSDYWGNKGGWCTATHECMSWCK

86.7%

NZ_FMPI01000012.1and 1 other:

NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08305_lanthipeptide

Lanthipeptides: BJR39_RS08305_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

CSTNTFSLSDYWGN G WCT +HECMSWCK

CSTNTFSLSDYWGNNGNWCTASHECMSWCK

86.7%

NZ_PCGR01000003.1and 1 other:

NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09620_lanthipeptide

Lanthipeptides: CQS04_RS09620_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLSDYWGN G WCT THECMSWCK

CTTNTFSLSDYWGNNGNWCTATHECMSWCK

83.3%

NZ_AP026714.1and 21 others:

Lanthipeptides: PO853_RS06515_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLSDYWGN+G WCT THECM WCK

CTTNTFSLSDYWGNKGNWCTATHECMGWCK

83.3%

NZ_MIFN01000022.1and 1 other:

NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15350_lanthipeptide

Lanthipeptides: BHL26_RS15350_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLSDYWGN G WC+L+HECMSWCK

CTTNTFSLSDYWGNDGSWCSLSHECMSWCK

83.3%

NZ_NUIO01000031.1and 1 other:

NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23160_lanthipeptide

Lanthipeptides: CN977_RS23160_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLSDYWGN G WCT THEC+SWCK

CTTNTFSLSDYWGNDGSWCTATHECLSWCK

80.0%

NZ_FNHR01000005.1and 1 other:

NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05590_lanthipeptide

Lanthipeptides: BLQ37_RS05590_lanthipeptide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

CSTNTFSLSDY GN G WCT++HECM+WCK

CSTNTFSLSDYMGNNGNWCTISHECMAWCK

MIBiG 4.0 matches for allorf_0097945_0098112

63.3%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

CSTNTFSLSDYWGNRGYWCTLTHECMSWCK

C+TNTFSLS+ GN G WCTLT EC C

CTTNTFSLSNALGNNGGWCTLTKECQPNCN

40.0%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

FSLSDYWGNRGYWCTLTHECMSWC

+++S GN+G +CTLT ECM C

YNISCRLGNKGAYCTLTVECMPSC

15.4%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTLTHECMSWC

CTL+ EC C

CTLSKECQPNC

allorf_0098227_0098397

Leader:

MNNLELGKYLESDMIAVTEEDVEGG

Core:

ATPAVATAALLAVGGFISHNTCPTTVCTRAC

Core with dehydrations:

ADhbPAVADhbAALLAVGGFIDhaHNDhbCysPDhbDhbVCysDhbRACys

antiSMASH-DB 4.0 matches for allorf_0098227_0098397

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: C3B71_RS16030_lanthipeptide

Lanthipeptides: C3B71_RS16030_lanthipeptide

ATPAVATAALLAVGGFISHNTCPTTVCTRAC

67.7%

NZ_NUIO01000031.1and 1 other:

NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23165_lanthipeptide

Lanthipeptides: CN977_RS23165_lanthipeptide

TPAVATAALLAVGGFISHNTCPTTVCTRAC

TP V+ AL AV G+IS NTCPTT CTRAC

TPTVS-IALTAVSGYISSNTCPTTACTRAC

60.6%

NZ_LR134317.1and 1 other:

NZ_LR134317.1 Lanthipeptides: EL136_RS01690_lanthipeptide

Lanthipeptides: EL136_RS01690_lanthipeptide

ATPAVATAALLAVGGFISHNTCPTTVCTRAC

ATP + A++ AV FIS NTCPTT CTRAC

ATPWLVKASV-AVTAFISANTCPTTSCTRAC

with 82 more sequence matches

Only the first 10 are displayed here.

58.1%

NZ_CP034414.1and 1 other:

NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide

Lanthipeptides: EI692_RS18435_lanthipeptide

TPAVATAALLAVGGFISHNTCPTTVCTRAC

TPA++ + V GFIS NTCP+T CTRAC

TPAIS----ILVSGFISTNTCPSTACTRAC

56.2%

NZ_CACZYW010000004.1and 3 others:

NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptideNZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptideNZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide

Lanthipeptides: HUF10_RS02820_lanthipeptide

TPAV-ATAALLAVGGFISHNTCPTTVCTRAC

TPA AT ++AV ++S TCPTT CTRAC

TPATPATPVIVAVSAYVSDKTCPTTACTRAC

54.8%

NZ_AP026714.1and 21 others:

Lanthipeptides: PO853_RS06520_lanthipeptide

ATPAVATAALLAVGGFISHNTCPTTVCTRAC

TP + +AV G+IS TCPT+VCTRAC

GTPTITIPISIAVSGWISDKTCPTSVCTRAC

54.8%

NZ_CP016767.1and 3 others:

NZ_CP016767.1 Lanthipeptides: BCV50_RS13415_lanthipeptideNZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptideNZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide

Lanthipeptides: BCV50_RS13415_lanthipeptide

TAALLAVGGFISHNTCPTTVCTRAC

T AL + G+IS NTCPTT CTRAC

TPALSVITGYISSNTCPTTACTRAC

54.8%

NZ_CP061868.1and 1 other:

NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide

Lanthipeptides: IE339_RS06335_lanthipeptide

TAALLAVGGFISHNTCPTTVCTRAC

T + AV G+IS NTCPTT CTRAC

TIVITAVTGYISTNTCPTTSCTRAC

54.8%

NZ_JALAPU010000003.1and 7 others:

Lanthipeptides: MOD17_RS07925_lanthipeptide

TAALLAVGGFISHNTCPTTVCTRAC

T AL V +IS NTCPTT CTRAC

TPALSVVTAYISSNTCPTTACTRAC

54.8%

NZ_QGEE01000020.1and 3 others:

NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06165_lanthipeptideNZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptideNZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptide

Lanthipeptides: DKP74_RS06165_lanthipeptide

TPAVATAALLAVGGFISHNTCPTTVCTRAC

TP + +A++ V GF+S +TCPTT CTRAC

TPVIGYSAVI-VSGFVSSHTCPTTACTRAC

54.5%

NZ_MIFN01000022.1and 1 other:

NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide

Lanthipeptides: BHL26_RS15355_lanthipeptide

TAALLAVGGFISHNTCPTTVCTRAC

T AL AV G+IS NTCP+T CTRAC

TGALTAVSGYISSNTCPSTACTRAC

51.6%

NZ_PCGR01000003.1and 1 other:

NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide

Lanthipeptides: CQS04_RS09625_lanthipeptide

AVATAALLAVGGFISHNTCPTTVCTRAC

A T + A+ G+IS N+CPTT CTRAC

ATPTIVITAITGYISANSCPTTACTRAC

46.9%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

TPAVATAALLAVGGFISHNTCPTTVCTRAC

TPA T + VG IS CPTT CT C

TPATPT---IVVG--ISVGLCPTTKCTSKC

MIBiG 4.0 matches for allorf_0098227_0098397

37.8%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

VATAALLAVGGFISHNTCPTTVCTRAC

VA A +AVG +S CPTT CT C

VAIQAGVAVG--VSAAFCPTTKCTSRC

22.6%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

CPTTVCTRAC

CPTT CT C

CPTTKCTSKC

allorf_0109463_0109555

Leader:

MWWWGGAGDVGGG

Core:

LVADGELVVSGGCGARV

Core with dehydrations:

LVADGELVVDhaGGCysGARV

antiSMASH-DB 4.0 matches for allorf_0109463_0109555

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0109463_0109555_lanthipeptide

Lanthipeptides: allorf_0109463_0109555_lanthipeptide

LVADGELVVSGGCGARV

15.0%

NZ_CP114040.1:

Lanthipeptides: O0S08_RS10560_lanthipeptide

ELVVSGGCGAR

E+ SGGCG++

EVHASGGCGSQ

allorf_0109479_0109712

Leader:

MLAMWVVVWWRMVSWSCLVAVGPEFEWAACALRELARAFVSSLALLGA

Core:

SSRSRVVDVGACGRAGCVLSEDWCAQSGA

Core with dehydrations:

DhaDhaRDhaRVVDVGACysGRAGCysVLDhaEDWCysAQDhaGA

antiSMASH-DB 4.0 matches for allorf_0109479_0109712

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0109479_0109712_lanthipeptide

Lanthipeptides: allorf_0109479_0109712_lanthipeptide

SSRSRVVDVGACGRAGCVLSEDWCAQSGA

34.5%

NZ_AP014940.1:

Lanthipeptides: allorf_3267938_3268081_lanthipeptide

ACGRAGCVLSEDWCAQSGA

AC RA +S CAQ GA

ACNRAARSVSRLPCAQRGA

21.2%

NZ_CP110813.1:

Lanthipeptides: allorf_5693634_5693777_lanthipeptide

RAGCVLSEDW

RAGCV S+ W

RAGCVESDRW

allorf_0109556_0109681

Leader:

MGCVRPSGARSRLRELACA

Core:

VGSVVPEPGCRRGCLWAGRLCA

Core with dehydrations:

VGDhaVVPEPGCysRRGCysLWAGRLCysA

antiSMASH-DB 4.0 matches for allorf_0109556_0109681

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0109556_0109681_lanthipeptide

Lanthipeptides: allorf_0109556_0109681_lanthipeptide

VGSVVPEPGCRRGCLWAGRLCA

36.4%

NZ_CP106798.1:

Lanthipeptides: allorf_8193611_8193688_lanthipeptide

VGSVVPEPGCRRGC

V SV PG R GC

VTSVADMPGTRSGC

24.0%

NZ_GL545262.1:

Lanthipeptides: HMPREF0798_RS11845_lanthipeptide

VGSVVPEPGCRRGCLWA

+ S+ PEP R W+

IQSMTPEPSVTRILTWS

with 2 more sequence matches

16.7%

NZ_QJTF01000024.1:

Lanthipeptides: allorf_35736_35903_lanthipeptide

PGCRRGCLWAGR

GC GC AGR

DGCSTGCTEAGR

14.3%

NC_014718.1:

Lanthipeptides: RBRH_RS14080_lanthipeptide

SVVPEPGCRR

+V P+PG R+

AVTPQPGTRQ

allorf_0109701_0109913

Leader:

MDRCSPDGPLFPRWTAVAAGYSGPTGRGRSNGA

Core:

WAVQRGVGGPTGPVQDPLAPFDCRQPGPRHRGNALRA

Core with dehydrations:

WAVQRGVGGPDhbGPVQDPLAPFDCysRQPGPRHRGNALRA

antiSMASH-DB 4.0 matches for allorf_0109701_0109913

100.0%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0109701_0109913_lanthipeptide

Lanthipeptides: allorf_0109701_0109913_lanthipeptide

WAVQRGVGGPTGPVQDPLAPFDCRQPGPRHRGNALRA

35.1%

NZ_CP072827.1:

Lanthipeptides: allorf_1271443_1271583_lanthipeptide

GGPTGP---VQDPLAPFDCRQPGPRHRGNA

GGP P V LA ++CR H GNA

GGPEHPSLRVGGALASYECRNRLCSHAGNA

29.7%

NZ_FNBR01000006.1and 1 other:

NZ_FUYT01000011.1 Lanthipeptides: allorf_180567_180686_lanthipeptide

Lanthipeptides: allorf_233241_233360_lanthipeptide

LAPFD-CRQPGPRHRGNALR

L P D CR PG R NA+R

LTPADSCRAPGYGTRANAMR

with 2 more sequence matches

26.1%

NZ_BNBI01000017.1:

Lanthipeptides: IE316_RS35725_lanthipeptide

WAVQRGVGG--PTGPVQDPLAPFDCRQPGPRHRGNA

W V+R +++PL D R+P PR R N+

WVVERTFAWLYQFKRLRNPLR--DTRRPPPRTRSNS

18.9%

NZ_NNBP01000005.1:

Lassopeptides: CG747_RS46885_lassopeptide

GGPTGPVQDPLAPFDC

GG V++ AP+DC

GGDDTGVENKRAPYDC

MIBiG 4.0 matches for allorf_0109701_0109913

13.5%

BGC0002150.2 (MBO0654592.1):

Lasso peptide: triculamin

QPGPRHRGNALRA

+PG RG +R

KPGDGIRGKGVRG

allorf_0111999_0112211

Leader:

MGRSAILAG

Core:

RPTCFQGPRRGRAASASHVQRMSLVEAQNRAAPTAPVTPSLIRASLSSATPVSGQRSASSR

Core with dehydrations:

RPDhbCysFQGPRRGRAADhaADhaHVQRMDhaLVEAQNRAAPDhbAPVDhbPDhaLIRADhaLDhaDhaADhbPVDhaGQRDhaADhaDhaR

antiSMASH-DB 4.0 matches for allorf_0111999_0112211

100.0%

NZ_CP027862.1:

Lanthipeptides: allorf_0111999_0112211_lanthipeptide

RPTCFQGPRRGRAASASHVQRMSLVEAQNRAAPTAPVTPSLIRASLSSATPVSGQRSASSR

11.5%

NZ_CP015591.1and 15 others:

NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide

Lanthipeptides: A7A70_RS27550_lanthipeptide

TAPVTPSLIRASLSSATPVSGQRSASSR

T P TP+++ A++++ + +SR

TTPATPTIVEATIAATVSICPTTKCTSR

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (4):

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 17.88 out of 21.84

Confidence: weak

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.38 out of 21.84

Confidence: weak

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 17.54 out of 27.78

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 22.04 out of 29.65

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

C3B71_RS00410 - Class II

Cleavage pHMM score: -6.80

RODEO score: 0

Monoisotopic mass: 4046.2 Da

Molecular weight: 4048.7 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 4066.7 Da N = 1; 4084.7 Da N = 2; 4102.8 Da N = 3

C3B71_RS16245 - Class II

Cleavage pHMM score: -6.00

RODEO score: 0

Monoisotopic mass: 4148.1 Da

Molecular weight: 4150.5 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 4168.5 Da N = 1; 4186.5 Da N = 2; 4204.5 Da N = 3; 4222.5 Da N = 4

allorf_0094367_0094588 - Class II

Cleavage pHMM score: -5.70

RODEO score: 0

Monoisotopic mass: 5046.7 Da

Molecular weight: 5049.9 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 5067.9 Da N = 1

allorf_0097945_0098112 - Class II

Cleavage pHMM score: -0.50

RODEO score: 0

Monoisotopic mass: 3434.5 Da

Molecular weight: 3436.8 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3454.8 Da N = 1; 3472.9 Da N = 2; 3490.9 Da N = 3; 3508.9 Da N = 4

allorf_0098227_0098397 - Class II

Cleavage pHMM score: -1.90

RODEO score: 0

Monoisotopic mass: 2890.5 Da

Molecular weight: 2892.4 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2910.4 Da N = 1; 2928.4 Da N = 2; 2946.4 Da N = 3; 2964.4 Da N = 4

allorf_0109463_0109555 - Class II

Cleavage pHMM score: -3.80

RODEO score: 0

Monoisotopic mass: 1582.8 Da

Molecular weight: 1583.8 Da

Number of bridges: 1

allorf_0109479_0109712 - Class II

Cleavage pHMM score: -5.80

RODEO score: 0

Monoisotopic mass: 2835.3 Da

Molecular weight: 2837.1 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2855.1 Da N = 1; 2873.2 Da N = 2

allorf_0109556_0109681 - Class II

Cleavage pHMM score: -3.90

RODEO score: 0

Monoisotopic mass: 2267.1 Da

Molecular weight: 2268.7 Da

Number of bridges: 1

allorf_0109701_0109913 - Class II

Cleavage pHMM score: -3.10

RODEO score: 0

Monoisotopic mass: 3915.0 Da

Molecular weight: 3917.4 Da

Number of bridges: 1

C3B71_RS16245 - Class II

Cleavage pHMM score: -6.00

RODEO score: 0

Monoisotopic mass: 4148.1 Da

Molecular weight: 4150.5 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 4168.5 Da N = 1; 4186.5 Da N = 2; 4204.5 Da N = 3; 4222.5 Da N = 4

allorf_0094367_0094588 - Class II

Cleavage pHMM score: -5.70

RODEO score: 0

Monoisotopic mass: 5046.7 Da

Molecular weight: 5049.9 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 5067.9 Da N = 1

allorf_0097945_0098112 - Class II

Cleavage pHMM score: -0.50

RODEO score: 0

Monoisotopic mass: 3434.5 Da

Molecular weight: 3436.8 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3454.8 Da N = 1; 3472.9 Da N = 2; 3490.9 Da N = 3; 3508.9 Da N = 4

allorf_0098227_0098397 - Class II

Cleavage pHMM score: -1.90

RODEO score: 0

Monoisotopic mass: 2890.5 Da

Molecular weight: 2892.4 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2910.4 Da N = 1; 2928.4 Da N = 2; 2946.4 Da N = 3; 2964.4 Da N = 4

allorf_0109463_0109555 - Class II

Cleavage pHMM score: -3.80

RODEO score: 0

Monoisotopic mass: 1582.8 Da

Molecular weight: 1583.8 Da

Number of bridges: 1

allorf_0109479_0109712 - Class II

Cleavage pHMM score: -5.80

RODEO score: 0

Monoisotopic mass: 2835.3 Da

Molecular weight: 2837.1 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2855.1 Da N = 1; 2873.2 Da N = 2

allorf_0109556_0109681 - Class II

Cleavage pHMM score: -3.90

RODEO score: 0

Monoisotopic mass: 2267.1 Da

Molecular weight: 2268.7 Da

Number of bridges: 1

allorf_0109701_0109913 - Class II

Cleavage pHMM score: -3.10

RODEO score: 0

Monoisotopic mass: 3915.0 Da

Molecular weight: 3917.4 Da

Number of bridges: 1

allorf_0111999_0112211 - Class II

Cleavage pHMM score: -3.10

RODEO score: 0

Monoisotopic mass: 6100.3 Da

Molecular weight: 6103.8 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 6121.8 Da N = 1; 6139.9 Da N = 2; 6157.9 Da N = 3; 6175.9 Da N = 4; 6193.9 Da N = 5; 6211.9 Da N = 6; 6230.0 Da N = 7; 6248.0 Da N = 8; 6266.0 Da N = 9; 6284.0 Da N = 10; 6302.0 Da N = 11; 6320.1 Da N = 12; 6338.1 Da N = 13; 6356.1 Da N = 14

TFBS definitions

Regulator	Description

NZ_CP027862.1 - Region 2 - terpene-precursor

Download region GenBank file

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Location: 2,039,357 - 2,060,502 nt. (total: 21,146 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: acyltransferase phosphorylase

C3B71_RS08465: thiamine-phosphate pyrophosphorylase

smcogs: SMCOG1280: thiamine-phosphate pyrophosphorylase

C3B71_RS08530: acyltransferase

smcogs: SMCOG1141: acyltransferase

Ligases: synthetase

C3B71_RS08490: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000677.5	0.42	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001911.3	0.38	terpene	raimonol	Streptomyces anulatus
BGC0000643.3	0.37	terpene	carotenoid	Brevundimonas vesicularis
BGC0002309.2	0.37	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000936.5	0.37	other (other)	pyocyanine	Pseudomonas aeruginosa PAO1
BGC0002578.2	0.37	other (other)	gaburedin A, gaburedin B, gaburedin C, gaburedin D, gaburedin E, gaburedin F	Streptomyces venezuelae ATCC 10712
BGC0000634.3	0.37	terpene	carotenoid	Brevundimonas sp. SD212
BGC0001456.3	0.37	terpene	isorenieratene	Streptomyces argillaceus
BGC0001910.4	0.36	terpene	cyslabdan A, cyslabdan B, cyslabdan C	Streptomyces cyslabdanicus
BGC0000678.5	0.36	terpene	pentalenolactone	Streptomyces avermitilis MA-4680 = NBRC 14893

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000677.5	0.42	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001911.3	0.38	terpene	raimonol	Streptomyces anulatus
BGC0000643.3	0.37	terpene	carotenoid	Brevundimonas vesicularis
BGC0002309.2	0.37	terpene	cattleyene	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000936.5	0.37	other (other)	pyocyanine	Pseudomonas aeruginosa PAO1
BGC0002578.2	0.37	other (other)	gaburedin A, gaburedin B, gaburedin C, gaburedin D, gaburedin E, gaburedin F	Streptomyces venezuelae ATCC 10712
BGC0000634.3	0.37	terpene	carotenoid	Brevundimonas sp. SD212
BGC0001456.3	0.37	terpene	isorenieratene	Streptomyces argillaceus
BGC0001910.4	0.36	terpene	cyslabdan A, cyslabdan B, cyslabdan C	Streptomyces cyslabdanicus
BGC0000678.5	0.36	terpene	pentalenolactone	Streptomyces avermitilis MA-4680 = NBRC 14893

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor	FPP	C15	acyclic	PP
diterpene precursor	GGPP	C20	acyclic	PP
sesterterpene precursor	GFPP	C25	acyclic	PP
triterpene precursor	HPP	C30	acyclic	PP

Genes with terpene domains:

C3B71_RS08490: PT_FPPS_like

Domain 1 (46 - 379): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

Transcription Factor Binding Sites

Binding sites found:

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 18.58 out of 23.79

Confidence: medium

AbrC3

Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 18.16 out of 18.16

Confidence: strong

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 23.58 out of 30.11

Confidence: medium

Additional weak hits (3):

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 17.50 out of 27.78

Confidence: weak

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 17.38 out of 28.19

Confidence: weak

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 22.10 out of 30.11

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
AbrC3	Antibiotic production activator
CelR	Cellobiose uptake repressor
IolR	Regulator of the inositol catabolism