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Overview
1.1
1.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP027862.1 (Actinomyces sp. Z16)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1 | lanthipeptide-class-ii | 88,439 | 116,261 |
Region 2 | terpene-precursor | 2,039,357 | 2,060,502 |  |

NZ_CP027862.1 - Region 1 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 88,439 - 116,261 nt. (total: 27,823 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
binding site
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
C3B71_RS15670: crotonyl-CoA reductase / alcohol dehydrogenase

smcogs
  SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase

Lyases: cyclase
C3B71_RS00445: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

C3B71_RS00455: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000520.5 |  | 0.62 | ribosomal | lacticin 3147 A1, lacticin 3147 A2 | Lactococcus lactis
BGC0001229.4 |  | 0.62 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000517.4 |  | 0.59 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0002110.3 |  | 0.57 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0000555.3 |  | 0.57 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0001555.4 |  | 0.51 | ribosomal | colicin V | Escherichia coli chi7122
BGC0000528.5 |  | 0.51 | ribosomal | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001311.5 |  | 0.51 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0001210.5 |  | 0.50 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0002698.2 |  | 0.50 | ribosomal | phaeornamide | Pseudophaeobacter arcticus DSM 23566

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000520.5 |  | 0.62 | ribosomal | lacticin 3147 A1, lacticin 3147 A2 | Lactococcus lactis
BGC0001229.4 |  | 0.62 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000517.4 |  | 0.59 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0002110.3 |  | 0.57 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0000555.3 |  | 0.57 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0001555.4 |  | 0.51 | ribosomal | colicin V | Escherichia coli chi7122
BGC0000528.5 |  | 0.51 | ribosomal | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001311.5 |  | 0.51 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0001210.5 |  | 0.50 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0002698.2 |  | 0.50 | ribosomal | phaeornamide | Pseudophaeobacter arcticus DSM 23566

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for C3B71_RS00445

C3B71_RS00410
Leader:
MPTPRAAGWSLLLVGIALSALAA
Core:
CTHLAWLWIIAIVVLVASIGTLAVAFVSDADGPGDGRRR
Core with dehydrations:
CysDhbHLAWLWIIAIVVLVADhaIGDhbLAVAFVDhaDADGPGDGRRR

#### antiSMASH-DB 4.0 matches for C3B71_RS00410

100.0%
NZ_CP027862.1:
Lanthipeptides: C3B71_RS00410_lanthipeptide
1
CTHLAWLWIIAIVVLVASIGTLAVAFVSDADGPGDGRRR
39
CTHLAWLWIIAIVVLVASIGTLAVAFVSDADGPGDGRRR
1
CTHLAWLWIIAIVVLVASIGTLAVAFVSDADGPGDGRRR
39
C3B71_RS16245
Leader:
MLAPHDLTGA
Core:
VVTADALHTDRHSAADTRPGRRLCAGRQGQPARPESEAEG
Core with dehydrations:
VVDhbADALHDhbDRHDhaAADDhbRPGRRLCysAGRQGQPARPEDhaEAEG

#### antiSMASH-DB 4.0 matches for C3B71_RS16245

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: C3B71_RS16245_lanthipeptide
Lanthipeptides: C3B71_RS16245_lanthipeptide
1
VVTADALHTDRHSAADTRPGRRLCAGRQGQPARPESEAEG
40
VVTADALHTDRHSAADTRPGRRLCAGRQGQPARPESEAEG
1
VVTADALHTDRHSAADTRPGRRLCAGRQGQPARPESEAEG
40
25.0%
NZ_CP013141.1:
Lanthipeptides: allorf_5320283_5320453_lanthipeptide
19
PGRRLCAGRQGQPARPE
35
PG+ GR GQPAR E
2
PGQGAQGGRPGQPARAE
18
17.5%
NZ_VBSN01000041.1:
Lanthipeptides: FEM33_RS15105_lanthipeptide
17
TRPGRRLCAGRQG
29
T PG+ CAG G
5
TAPGQSCCAGSNG
17
allorf_0094367_0094588
Leader:
MCIGGCGLSARVIGANVVLQTGVLGG
Core:
CLLPAFAVWTAVPCLDRVSLFGPPLCAAWAVQTDARGPNRRGRSKPR
Core with dehydrations:
CysLLPAFAVWDhbAVPCysLDRVDhaLFGPPLCysAAWAVQDhbDARGPNRRGRDhaKPR

#### antiSMASH-DB 4.0 matches for allorf_0094367_0094588

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0094367_0094588_lanthipeptide
Lanthipeptides: allorf_0094367_0094588_lanthipeptide
1
CLLPAFAVWTAVPCLDRVSLFGPPLCAAWAVQTDARGPNRRGRSKPR
47
CLLPAFAVWTAVPCLDRVSLFGPPLCAAWAVQTDARGPNRRGRSKPR
1
CLLPAFAVWTAVPCLDRVSLFGPPLCAAWAVQTDARGPNRRGRSKPR
47
21.6%
NZ_CP027306.1:
Lanthipeptides: allorf_8952890_8953126_lanthipeptide
19
SLFGPPLCAAWAVQT--DARGPNR
40
L GPPL A W ++ D RG R
20
GLLGPPLSALWQRESLFDERGLFR
43
11.5%
NZ_KB900614.1:
Lanthipeptides: allorf_2973093_2973293_lanthipeptide
2
LLPAFAVWTAVPCLDR
17
L+PAF+++ +P L
9
LIPAFSIFMTMPSLGH
24

#### MIBiG 4.0 matches for allorf_0094367_0094588

8.5%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
27
AAWAVQTDARGPN
39
W T PN
16
GGWCTLTKECQPN
28
allorf_0097945_0098112
Leader:
MESQAEVTWIEEVGEQSFDTDVFGA
Core:
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
Core with dehydrations:
CysDhaDhbNDhbFDhaLDhaDYWGNRGYWCysDhbLDhbHECysMDhaWCysK

#### antiSMASH-DB 4.0 matches for allorf_0097945_0098112

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide
Lanthipeptides: allorf_0097945_0098112_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
90.0%
NZ_QGEE01000020.1 and 5 others:
NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06160_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide
Lanthipeptides: DKP74_RS06160_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDYWGNRG WCTL+HECM+WCK
1
CSTNTFSLSDYWGNRGNWCTLSHECMAWCK
30
86.7%
NZ_BLIS01000009.1 and 7 others:
NZ_BLIS01000009.1 Lanthipeptides: GVO03_RS04820_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide
Lanthipeptides: GVO03_RS04820_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLSDYWGN+G WCTLTHECM+WCK
1
CTTNTFSLSDYWGNKGNWCTLTHECMNWCK
30
with 106 more sequence matches
Only the first 10 are displayed here.
86.7%
NZ_CACZYW010000004.1 and 1 other:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide
Lanthipeptides: HUF10_RS02825_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDYWGN G WCTL+HECM+WCK
1
CSTNTFSLSDYWGNNGNWCTLSHECMAWCK
30
86.7%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18440_lanthipeptide
Lanthipeptides: EI692_RS18440_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDYWGN+G WCT++HECMSWCK
1
CSTNTFSLSDYWGNKGGWCTISHECMSWCK
30
86.7%
NZ_CP051884.1 and 2 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide
Lanthipeptides: HGK68_RS15125_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDYWGN G+ CT+THECMSWCK
1
CSTNTFSLSDYWGNNGWLCTITHECMSWCK
30
86.7%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06330_lanthipeptide
Lanthipeptides: IE339_RS06330_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLSDYWGN+G WCT THECMSWCK
1
CTTNTFSLSDYWGNKGGWCTATHECMSWCK
30
86.7%
NZ_FMPI01000012.1 and 1 other:
NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08305_lanthipeptide
Lanthipeptides: BJR39_RS08305_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDYWGN G WCT +HECMSWCK
1
CSTNTFSLSDYWGNNGNWCTASHECMSWCK
30
86.7%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09620_lanthipeptide
Lanthipeptides: CQS04_RS09620_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLSDYWGN G WCT THECMSWCK
1
CTTNTFSLSDYWGNNGNWCTATHECMSWCK
30
83.3%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06515_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide
Lanthipeptides: PO853_RS06515_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLSDYWGN+G WCT THECM WCK
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
83.3%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15350_lanthipeptide
Lanthipeptides: BHL26_RS15350_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLSDYWGN G WC+L+HECMSWCK
1
CTTNTFSLSDYWGNDGSWCSLSHECMSWCK
30
83.3%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23160_lanthipeptide
Lanthipeptides: CN977_RS23160_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLSDYWGN G WCT THEC+SWCK
1
CTTNTFSLSDYWGNDGSWCTATHECLSWCK
30
80.0%
NZ_FNHR01000005.1 and 1 other:
NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05590_lanthipeptide
Lanthipeptides: BLQ37_RS05590_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDY GN G WCT++HECM+WCK
1
CSTNTFSLSDYMGNNGNWCTISHECMAWCK
30

#### MIBiG 4.0 matches for allorf_0097945_0098112

63.3%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLS+ GN G WCTLT EC C
1
CTTNTFSLSNALGNNGGWCTLTKECQPNCN
30
40.0%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
6
FSLSDYWGNRGYWCTLTHECMSWC
29
+++S GN+G +CTLT ECM C
4
YNISCRLGNKGAYCTLTVECMPSC
27
15.4%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
CTLTHECMSWC
29
CTL+ EC C
28
CTLSKECQPNC
38
allorf_0098227_0098397
Leader:
MNNLELGKYLESDMIAVTEEDVEGG
Core:
ATPAVATAALLAVGGFISHNTCPTTVCTRAC
Core with dehydrations:
ADhbPAVADhbAALLAVGGFIDhaHNDhbCysPDhbDhbVCysDhbRACys

#### antiSMASH-DB 4.0 matches for allorf_0098227_0098397

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: C3B71_RS16030_lanthipeptide
Lanthipeptides: C3B71_RS16030_lanthipeptide
1
ATPAVATAALLAVGGFISHNTCPTTVCTRAC
31
ATPAVATAALLAVGGFISHNTCPTTVCTRAC
1
ATPAVATAALLAVGGFISHNTCPTTVCTRAC
31
67.7%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23165_lanthipeptide
Lanthipeptides: CN977_RS23165_lanthipeptide
2
TPAVATAALLAVGGFISHNTCPTTVCTRAC
31
TP V+ AL AV G+IS NTCPTT CTRAC
2
TPTVS-IALTAVSGYISSNTCPTTACTRAC
30
60.6%
NZ_LR134317.1 and 1 other:
NZ_LR134317.1 Lanthipeptides: EL136_RS01690_lanthipeptide
Lanthipeptides: EL136_RS01690_lanthipeptide
1
ATPAVATAALLAVGGFISHNTCPTTVCTRAC
31
ATP + A++ AV FIS NTCPTT CTRAC
4
ATPWLVKASV-AVTAFISANTCPTTSCTRAC
33
with 82 more sequence matches
Only the first 10 are displayed here.
58.1%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide
Lanthipeptides: EI692_RS18435_lanthipeptide
2
TPAVATAALLAVGGFISHNTCPTTVCTRAC
31
TPA++ + V GFIS NTCP+T CTRAC
2
TPAIS----ILVSGFISTNTCPSTACTRAC
27
56.2%
NZ_CACZYW010000004.1 and 3 others:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide
Lanthipeptides: HUF10_RS02820_lanthipeptide
2
TPAV-ATAALLAVGGFISHNTCPTTVCTRAC
31
TPA AT ++AV ++S TCPTT CTRAC
2
TPATPATPVIVAVSAYVSDKTCPTTACTRAC
32
54.8%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide
Lanthipeptides: PO853_RS06520_lanthipeptide
1
ATPAVATAALLAVGGFISHNTCPTTVCTRAC
31
TP + +AV G+IS TCPT+VCTRAC
1
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
31
54.8%
NZ_CP016767.1 and 3 others:
NZ_CP016767.1 Lanthipeptides: BCV50_RS13415_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide
Lanthipeptides: BCV50_RS13415_lanthipeptide
7
TAALLAVGGFISHNTCPTTVCTRAC
31
T AL + G+IS NTCPTT CTRAC
2
TPALSVITGYISSNTCPTTACTRAC
26
54.8%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide
Lanthipeptides: IE339_RS06335_lanthipeptide
7
TAALLAVGGFISHNTCPTTVCTRAC
31
T + AV G+IS NTCPTT CTRAC
4
TIVITAVTGYISTNTCPTTSCTRAC
28
54.8%
NZ_JALAPU010000003.1 and 7 others:
NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07925_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00585_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00585_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17010_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17010_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04640_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04640_lanthipeptide
Lanthipeptides: MOD17_RS07925_lanthipeptide
7
TAALLAVGGFISHNTCPTTVCTRAC
31
T AL V +IS NTCPTT CTRAC
2
TPALSVVTAYISSNTCPTTACTRAC
26
54.8%
NZ_QGEE01000020.1 and 3 others:
NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06165_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptide
Lanthipeptides: DKP74_RS06165_lanthipeptide
2
TPAVATAALLAVGGFISHNTCPTTVCTRAC
31
TP + +A++ V GF+S +TCPTT CTRAC
2
TPVIGYSAVI-VSGFVSSHTCPTTACTRAC
30
54.5%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide
Lanthipeptides: BHL26_RS15355_lanthipeptide
7
TAALLAVGGFISHNTCPTTVCTRAC
31
T AL AV G+IS NTCP+T CTRAC
9
TGALTAVSGYISSNTCPSTACTRAC
33
51.6%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide
Lanthipeptides: CQS04_RS09625_lanthipeptide
4
AVATAALLAVGGFISHNTCPTTVCTRAC
31
A T + A+ G+IS N+CPTT CTRAC
1
ATPTIVITAITGYISANSCPTTACTRAC
28
46.9%
NZ_NUML01000015.1:
Lanthipeptides: COD66_RS20140_lanthipeptide
2
TPAVATAALLAVGGFISHNTCPTTVCTRAC
31
TPA T + VG IS CPTT CT C
8
TPATPT---IVVG--ISVGLCPTTKCTSKC
32

#### MIBiG 4.0 matches for allorf_0098227_0098397

37.8%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
5
VATAALLAVGGFISHNTCPTTVCTRAC
31
VA A +AVG +S CPTT CT C
13
VAIQAGVAVG--VSAAFCPTTKCTSRC
37
22.6%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
22
CPTTVCTRAC
31
CPTT CT C
17
CPTTKCTSKC
26
allorf_0109463_0109555
Leader:
MWWWGGAGDVGGG
Core:
LVADGELVVSGGCGARV
Core with dehydrations:
LVADGELVVDhaGGCysGARV

#### antiSMASH-DB 4.0 matches for allorf_0109463_0109555

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0109463_0109555_lanthipeptide
Lanthipeptides: allorf_0109463_0109555_lanthipeptide
1
LVADGELVVSGGCGARV
17
LVADGELVVSGGCGARV
1
LVADGELVVSGGCGARV
17
15.0%
NZ_CP114040.1:
Lanthipeptides: O0S08_RS10560_lanthipeptide
6
ELVVSGGCGAR
16
E+ SGGCG++
2
EVHASGGCGSQ
12
allorf_0109479_0109712
Leader:
MLAMWVVVWWRMVSWSCLVAVGPEFEWAACALRELARAFVSSLALLGA
Core:
SSRSRVVDVGACGRAGCVLSEDWCAQSGA
Core with dehydrations:
DhaDhaRDhaRVVDVGACysGRAGCysVLDhaEDWCysAQDhaGA

#### antiSMASH-DB 4.0 matches for allorf_0109479_0109712

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0109479_0109712_lanthipeptide
Lanthipeptides: allorf_0109479_0109712_lanthipeptide
1
SSRSRVVDVGACGRAGCVLSEDWCAQSGA
29
SSRSRVVDVGACGRAGCVLSEDWCAQSGA
1
SSRSRVVDVGACGRAGCVLSEDWCAQSGA
29
34.5%
NZ_AP014940.1:
Lanthipeptides: allorf_3267938_3268081_lanthipeptide
11
ACGRAGCVLSEDWCAQSGA
29
AC RA +S CAQ GA
4
ACNRAARSVSRLPCAQRGA
22
21.2%
NZ_CP110813.1:
Lanthipeptides: allorf_5693634_5693777_lanthipeptide
14
RAGCVLSEDW
23
RAGCV S+ W
20
RAGCVESDRW
29
allorf_0109556_0109681
Leader:
MGCVRPSGARSRLRELACA
Core:
VGSVVPEPGCRRGCLWAGRLCA
Core with dehydrations:
VGDhaVVPEPGCysRRGCysLWAGRLCysA

#### antiSMASH-DB 4.0 matches for allorf_0109556_0109681

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0109556_0109681_lanthipeptide
Lanthipeptides: allorf_0109556_0109681_lanthipeptide
1
VGSVVPEPGCRRGCLWAGRLCA
22
VGSVVPEPGCRRGCLWAGRLCA
1
VGSVVPEPGCRRGCLWAGRLCA
22
36.4%
NZ_CP106798.1:
Lanthipeptides: allorf_8193611_8193688_lanthipeptide
1
VGSVVPEPGCRRGC
14
V SV PG R GC
1
VTSVADMPGTRSGC
14
24.0%
NZ_GL545262.1:
Lanthipeptides: HMPREF0798_RS11845_lanthipeptide
1
VGSVVPEPGCRRGCLWA
17
+ S+ PEP R W+
1
IQSMTPEPSVTRILTWS
17
with 2 more sequence matches
16.7%
NZ_QJTF01000024.1:
Lanthipeptides: allorf_35736_35903_lanthipeptide
8
PGCRRGCLWAGR
19
GC GC AGR
17
DGCSTGCTEAGR
28
14.3%
NC_014718.1:
Lanthipeptides: RBRH_RS14080_lanthipeptide
3
SVVPEPGCRR
12
+V P+PG R+
24
AVTPQPGTRQ
33
allorf_0109701_0109913
Leader:
MDRCSPDGPLFPRWTAVAAGYSGPTGRGRSNGA
Core:
WAVQRGVGGPTGPVQDPLAPFDCRQPGPRHRGNALRA
Core with dehydrations:
WAVQRGVGGPDhbGPVQDPLAPFDCysRQPGPRHRGNALRA

#### antiSMASH-DB 4.0 matches for allorf_0109701_0109913

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0109701_0109913_lanthipeptide
Lanthipeptides: allorf_0109701_0109913_lanthipeptide
1
WAVQRGVGGPTGPVQDPLAPFDCRQPGPRHRGNALRA
37
WAVQRGVGGPTGPVQDPLAPFDCRQPGPRHRGNALRA
1
WAVQRGVGGPTGPVQDPLAPFDCRQPGPRHRGNALRA
37
35.1%
NZ_CP072827.1:
Lanthipeptides: allorf_1271443_1271583_lanthipeptide
8
GGPTGP---VQDPLAPFDCRQPGPRHRGNA
34
GGP P V LA ++CR H GNA
5
GGPEHPSLRVGGALASYECRNRLCSHAGNA
34
29.7%
NZ_FNBR01000006.1 and 1 other:
NZ_FUYT01000011.1 Lanthipeptides: allorf_180567_180686_lanthipeptide
Lanthipeptides: allorf_233241_233360_lanthipeptide
18
LAPFD-CRQPGPRHRGNALR
36
L P D CR PG R NA+R
1
LTPADSCRAPGYGTRANAMR
20
with 2 more sequence matches
26.1%
NZ_BNBI01000017.1:
Lanthipeptides: IE316_RS35725_lanthipeptide
1
WAVQRGVGG--PTGPVQDPLAPFDCRQPGPRHRGNA
34
W V+R +++PL D R+P PR R N+
7
WVVERTFAWLYQFKRLRNPLR--DTRRPPPRTRSNS
40
18.9%
NZ_NNBP01000005.1:
Lassopeptides: CG747_RS46885_lassopeptide
8
GGPTGPVQDPLAPFDC
23
GG V++ AP+DC
1
GGDDTGVENKRAPYDC
16

#### MIBiG 4.0 matches for allorf_0109701_0109913

13.5%
BGC0002150.2 (MBO0654592.1):
Lasso peptide: triculamin
25
QPGPRHRGNALRA
37
+PG RG +R
5
KPGDGIRGKGVRG
17

#### Lanthipeptide(s) for C3B71_RS00455

C3B71_RS16245
Leader:
MLAPHDLTGA
Core:
VVTADALHTDRHSAADTRPGRRLCAGRQGQPARPESEAEG
Core with dehydrations:
VVDhbADALHDhbDRHDhaAADDhbRPGRRLCysAGRQGQPARPEDhaEAEG

#### antiSMASH-DB 4.0 matches for C3B71_RS16245

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: C3B71_RS16245_lanthipeptide
Lanthipeptides: C3B71_RS16245_lanthipeptide
1
VVTADALHTDRHSAADTRPGRRLCAGRQGQPARPESEAEG
40
VVTADALHTDRHSAADTRPGRRLCAGRQGQPARPESEAEG
1
VVTADALHTDRHSAADTRPGRRLCAGRQGQPARPESEAEG
40
25.0%
NZ_CP013141.1:
Lanthipeptides: allorf_5320283_5320453_lanthipeptide
19
PGRRLCAGRQGQPARPE
35
PG+ GR GQPAR E
2
PGQGAQGGRPGQPARAE
18
17.5%
NZ_VBSN01000041.1:
Lanthipeptides: FEM33_RS15105_lanthipeptide
17
TRPGRRLCAGRQG
29
T PG+ CAG G
5
TAPGQSCCAGSNG
17
allorf_0094367_0094588
Leader:
MCIGGCGLSARVIGANVVLQTGVLGG
Core:
CLLPAFAVWTAVPCLDRVSLFGPPLCAAWAVQTDARGPNRRGRSKPR
Core with dehydrations:
CysLLPAFAVWDhbAVPCysLDRVDhaLFGPPLCysAAWAVQDhbDARGPNRRGRDhaKPR

#### antiSMASH-DB 4.0 matches for allorf_0094367_0094588

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0094367_0094588_lanthipeptide
Lanthipeptides: allorf_0094367_0094588_lanthipeptide
1
CLLPAFAVWTAVPCLDRVSLFGPPLCAAWAVQTDARGPNRRGRSKPR
47
CLLPAFAVWTAVPCLDRVSLFGPPLCAAWAVQTDARGPNRRGRSKPR
1
CLLPAFAVWTAVPCLDRVSLFGPPLCAAWAVQTDARGPNRRGRSKPR
47
21.6%
NZ_CP027306.1:
Lanthipeptides: allorf_8952890_8953126_lanthipeptide
19
SLFGPPLCAAWAVQT--DARGPNR
40
L GPPL A W ++ D RG R
20
GLLGPPLSALWQRESLFDERGLFR
43
11.5%
NZ_KB900614.1:
Lanthipeptides: allorf_2973093_2973293_lanthipeptide
2
LLPAFAVWTAVPCLDR
17
L+PAF+++ +P L
9
LIPAFSIFMTMPSLGH
24

#### MIBiG 4.0 matches for allorf_0094367_0094588

8.5%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
27
AAWAVQTDARGPN
39
W T PN
16
GGWCTLTKECQPN
28
allorf_0097945_0098112
Leader:
MESQAEVTWIEEVGEQSFDTDVFGA
Core:
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
Core with dehydrations:
CysDhaDhbNDhbFDhaLDhaDYWGNRGYWCysDhbLDhbHECysMDhaWCysK

#### antiSMASH-DB 4.0 matches for allorf_0097945_0098112

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide
Lanthipeptides: allorf_0097945_0098112_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
90.0%
NZ_QGEE01000020.1 and 5 others:
NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06160_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide
Lanthipeptides: DKP74_RS06160_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDYWGNRG WCTL+HECM+WCK
1
CSTNTFSLSDYWGNRGNWCTLSHECMAWCK
30
86.7%
NZ_BLIS01000009.1 and 7 others:
NZ_BLIS01000009.1 Lanthipeptides: GVO03_RS04820_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide
Lanthipeptides: GVO03_RS04820_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLSDYWGN+G WCTLTHECM+WCK
1
CTTNTFSLSDYWGNKGNWCTLTHECMNWCK
30
with 106 more sequence matches
Only the first 10 are displayed here.
86.7%
NZ_CACZYW010000004.1 and 1 other:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide
Lanthipeptides: HUF10_RS02825_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDYWGN G WCTL+HECM+WCK
1
CSTNTFSLSDYWGNNGNWCTLSHECMAWCK
30
86.7%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18440_lanthipeptide
Lanthipeptides: EI692_RS18440_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDYWGN+G WCT++HECMSWCK
1
CSTNTFSLSDYWGNKGGWCTISHECMSWCK
30
86.7%
NZ_CP051884.1 and 2 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide
Lanthipeptides: HGK68_RS15125_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDYWGN G+ CT+THECMSWCK
1
CSTNTFSLSDYWGNNGWLCTITHECMSWCK
30
86.7%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06330_lanthipeptide
Lanthipeptides: IE339_RS06330_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLSDYWGN+G WCT THECMSWCK
1
CTTNTFSLSDYWGNKGGWCTATHECMSWCK
30
86.7%
NZ_FMPI01000012.1 and 1 other:
NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08305_lanthipeptide
Lanthipeptides: BJR39_RS08305_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDYWGN G WCT +HECMSWCK
1
CSTNTFSLSDYWGNNGNWCTASHECMSWCK
30
86.7%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09620_lanthipeptide
Lanthipeptides: CQS04_RS09620_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLSDYWGN G WCT THECMSWCK
1
CTTNTFSLSDYWGNNGNWCTATHECMSWCK
30
83.3%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06515_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide
Lanthipeptides: PO853_RS06515_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLSDYWGN+G WCT THECM WCK
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
83.3%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15350_lanthipeptide
Lanthipeptides: BHL26_RS15350_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLSDYWGN G WC+L+HECMSWCK
1
CTTNTFSLSDYWGNDGSWCSLSHECMSWCK
30
83.3%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23160_lanthipeptide
Lanthipeptides: CN977_RS23160_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLSDYWGN G WCT THEC+SWCK
1
CTTNTFSLSDYWGNDGSWCTATHECLSWCK
30
80.0%
NZ_FNHR01000005.1 and 1 other:
NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05590_lanthipeptide
Lanthipeptides: BLQ37_RS05590_lanthipeptide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
CSTNTFSLSDY GN G WCT++HECM+WCK
1
CSTNTFSLSDYMGNNGNWCTISHECMAWCK
30

#### MIBiG 4.0 matches for allorf_0097945_0098112

63.3%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
C+TNTFSLS+ GN G WCTLT EC C
1
CTTNTFSLSNALGNNGGWCTLTKECQPNCN
30
40.0%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
6
FSLSDYWGNRGYWCTLTHECMSWC
29
+++S GN+G +CTLT ECM C
4
YNISCRLGNKGAYCTLTVECMPSC
27
15.4%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
CTLTHECMSWC
29
CTL+ EC C
28
CTLSKECQPNC
38
allorf_0098227_0098397
Leader:
MNNLELGKYLESDMIAVTEEDVEGG
Core:
ATPAVATAALLAVGGFISHNTCPTTVCTRAC
Core with dehydrations:
ADhbPAVADhbAALLAVGGFIDhaHNDhbCysPDhbDhbVCysDhbRACys

#### antiSMASH-DB 4.0 matches for allorf_0098227_0098397

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: C3B71_RS16030_lanthipeptide
Lanthipeptides: C3B71_RS16030_lanthipeptide
1
ATPAVATAALLAVGGFISHNTCPTTVCTRAC
31
ATPAVATAALLAVGGFISHNTCPTTVCTRAC
1
ATPAVATAALLAVGGFISHNTCPTTVCTRAC
31
67.7%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23165_lanthipeptide
Lanthipeptides: CN977_RS23165_lanthipeptide
2
TPAVATAALLAVGGFISHNTCPTTVCTRAC
31
TP V+ AL AV G+IS NTCPTT CTRAC
2
TPTVS-IALTAVSGYISSNTCPTTACTRAC
30
60.6%
NZ_LR134317.1 and 1 other:
NZ_LR134317.1 Lanthipeptides: EL136_RS01690_lanthipeptide
Lanthipeptides: EL136_RS01690_lanthipeptide
1
ATPAVATAALLAVGGFISHNTCPTTVCTRAC
31
ATP + A++ AV FIS NTCPTT CTRAC
4
ATPWLVKASV-AVTAFISANTCPTTSCTRAC
33
with 82 more sequence matches
Only the first 10 are displayed here.
58.1%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide
Lanthipeptides: EI692_RS18435_lanthipeptide
2
TPAVATAALLAVGGFISHNTCPTTVCTRAC
31
TPA++ + V GFIS NTCP+T CTRAC
2
TPAIS----ILVSGFISTNTCPSTACTRAC
27
56.2%
NZ_CACZYW010000004.1 and 3 others:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide
Lanthipeptides: HUF10_RS02820_lanthipeptide
2
TPAV-ATAALLAVGGFISHNTCPTTVCTRAC
31
TPA AT ++AV ++S TCPTT CTRAC
2
TPATPATPVIVAVSAYVSDKTCPTTACTRAC
32
54.8%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide
Lanthipeptides: PO853_RS06520_lanthipeptide
1
ATPAVATAALLAVGGFISHNTCPTTVCTRAC
31
TP + +AV G+IS TCPT+VCTRAC
1
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
31
54.8%
NZ_CP016767.1 and 3 others:
NZ_CP016767.1 Lanthipeptides: BCV50_RS13415_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide
Lanthipeptides: BCV50_RS13415_lanthipeptide
7
TAALLAVGGFISHNTCPTTVCTRAC
31
T AL + G+IS NTCPTT CTRAC
2
TPALSVITGYISSNTCPTTACTRAC
26
54.8%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide
Lanthipeptides: IE339_RS06335_lanthipeptide
7
TAALLAVGGFISHNTCPTTVCTRAC
31
T + AV G+IS NTCPTT CTRAC
4
TIVITAVTGYISTNTCPTTSCTRAC
28
54.8%
NZ_JALAPU010000003.1 and 7 others:
NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07925_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00585_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00585_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17010_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17010_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04640_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04640_lanthipeptide
Lanthipeptides: MOD17_RS07925_lanthipeptide
7
TAALLAVGGFISHNTCPTTVCTRAC
31
T AL V +IS NTCPTT CTRAC
2
TPALSVVTAYISSNTCPTTACTRAC
26
54.8%
NZ_QGEE01000020.1 and 3 others:
NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06165_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptide
Lanthipeptides: DKP74_RS06165_lanthipeptide
2
TPAVATAALLAVGGFISHNTCPTTVCTRAC
31
TP + +A++ V GF+S +TCPTT CTRAC
2
TPVIGYSAVI-VSGFVSSHTCPTTACTRAC
30
54.5%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide
Lanthipeptides: BHL26_RS15355_lanthipeptide
7
TAALLAVGGFISHNTCPTTVCTRAC
31
T AL AV G+IS NTCP+T CTRAC
9
TGALTAVSGYISSNTCPSTACTRAC
33
51.6%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide
Lanthipeptides: CQS04_RS09625_lanthipeptide
4
AVATAALLAVGGFISHNTCPTTVCTRAC
31
A T + A+ G+IS N+CPTT CTRAC
1
ATPTIVITAITGYISANSCPTTACTRAC
28
46.9%
NZ_NUML01000015.1:
Lanthipeptides: COD66_RS20140_lanthipeptide
2
TPAVATAALLAVGGFISHNTCPTTVCTRAC
31
TPA T + VG IS CPTT CT C
8
TPATPT---IVVG--ISVGLCPTTKCTSKC
32

#### MIBiG 4.0 matches for allorf_0098227_0098397

37.8%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
5
VATAALLAVGGFISHNTCPTTVCTRAC
31
VA A +AVG +S CPTT CT C
13
VAIQAGVAVG--VSAAFCPTTKCTSRC
37
22.6%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
22
CPTTVCTRAC
31
CPTT CT C
17
CPTTKCTSKC
26
allorf_0109463_0109555
Leader:
MWWWGGAGDVGGG
Core:
LVADGELVVSGGCGARV
Core with dehydrations:
LVADGELVVDhaGGCysGARV

#### antiSMASH-DB 4.0 matches for allorf_0109463_0109555

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0109463_0109555_lanthipeptide
Lanthipeptides: allorf_0109463_0109555_lanthipeptide
1
LVADGELVVSGGCGARV
17
LVADGELVVSGGCGARV
1
LVADGELVVSGGCGARV
17
15.0%
NZ_CP114040.1:
Lanthipeptides: O0S08_RS10560_lanthipeptide
6
ELVVSGGCGAR
16
E+ SGGCG++
2
EVHASGGCGSQ
12
allorf_0109479_0109712
Leader:
MLAMWVVVWWRMVSWSCLVAVGPEFEWAACALRELARAFVSSLALLGA
Core:
SSRSRVVDVGACGRAGCVLSEDWCAQSGA
Core with dehydrations:
DhaDhaRDhaRVVDVGACysGRAGCysVLDhaEDWCysAQDhaGA

#### antiSMASH-DB 4.0 matches for allorf_0109479_0109712

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0109479_0109712_lanthipeptide
Lanthipeptides: allorf_0109479_0109712_lanthipeptide
1
SSRSRVVDVGACGRAGCVLSEDWCAQSGA
29
SSRSRVVDVGACGRAGCVLSEDWCAQSGA
1
SSRSRVVDVGACGRAGCVLSEDWCAQSGA
29
34.5%
NZ_AP014940.1:
Lanthipeptides: allorf_3267938_3268081_lanthipeptide
11
ACGRAGCVLSEDWCAQSGA
29
AC RA +S CAQ GA
4
ACNRAARSVSRLPCAQRGA
22
21.2%
NZ_CP110813.1:
Lanthipeptides: allorf_5693634_5693777_lanthipeptide
14
RAGCVLSEDW
23
RAGCV S+ W
20
RAGCVESDRW
29
allorf_0109556_0109681
Leader:
MGCVRPSGARSRLRELACA
Core:
VGSVVPEPGCRRGCLWAGRLCA
Core with dehydrations:
VGDhaVVPEPGCysRRGCysLWAGRLCysA

#### antiSMASH-DB 4.0 matches for allorf_0109556_0109681

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0109556_0109681_lanthipeptide
Lanthipeptides: allorf_0109556_0109681_lanthipeptide
1
VGSVVPEPGCRRGCLWAGRLCA
22
VGSVVPEPGCRRGCLWAGRLCA
1
VGSVVPEPGCRRGCLWAGRLCA
22
36.4%
NZ_CP106798.1:
Lanthipeptides: allorf_8193611_8193688_lanthipeptide
1
VGSVVPEPGCRRGC
14
V SV PG R GC
1
VTSVADMPGTRSGC
14
24.0%
NZ_GL545262.1:
Lanthipeptides: HMPREF0798_RS11845_lanthipeptide
1
VGSVVPEPGCRRGCLWA
17
+ S+ PEP R W+
1
IQSMTPEPSVTRILTWS
17
with 2 more sequence matches
16.7%
NZ_QJTF01000024.1:
Lanthipeptides: allorf_35736_35903_lanthipeptide
8
PGCRRGCLWAGR
19
GC GC AGR
17
DGCSTGCTEAGR
28
14.3%
NC_014718.1:
Lanthipeptides: RBRH_RS14080_lanthipeptide
3
SVVPEPGCRR
12
+V P+PG R+
24
AVTPQPGTRQ
33
allorf_0109701_0109913
Leader:
MDRCSPDGPLFPRWTAVAAGYSGPTGRGRSNGA
Core:
WAVQRGVGGPTGPVQDPLAPFDCRQPGPRHRGNALRA
Core with dehydrations:
WAVQRGVGGPDhbGPVQDPLAPFDCysRQPGPRHRGNALRA

#### antiSMASH-DB 4.0 matches for allorf_0109701_0109913

100.0%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0109701_0109913_lanthipeptide
Lanthipeptides: allorf_0109701_0109913_lanthipeptide
1
WAVQRGVGGPTGPVQDPLAPFDCRQPGPRHRGNALRA
37
WAVQRGVGGPTGPVQDPLAPFDCRQPGPRHRGNALRA
1
WAVQRGVGGPTGPVQDPLAPFDCRQPGPRHRGNALRA
37
35.1%
NZ_CP072827.1:
Lanthipeptides: allorf_1271443_1271583_lanthipeptide
8
GGPTGP---VQDPLAPFDCRQPGPRHRGNA
34
GGP P V LA ++CR H GNA
5
GGPEHPSLRVGGALASYECRNRLCSHAGNA
34
29.7%
NZ_FNBR01000006.1 and 1 other:
NZ_FUYT01000011.1 Lanthipeptides: allorf_180567_180686_lanthipeptide
Lanthipeptides: allorf_233241_233360_lanthipeptide
18
LAPFD-CRQPGPRHRGNALR
36
L P D CR PG R NA+R
1
LTPADSCRAPGYGTRANAMR
20
with 2 more sequence matches
26.1%
NZ_BNBI01000017.1:
Lanthipeptides: IE316_RS35725_lanthipeptide
1
WAVQRGVGG--PTGPVQDPLAPFDCRQPGPRHRGNA
34
W V+R +++PL D R+P PR R N+
7
WVVERTFAWLYQFKRLRNPLR--DTRRPPPRTRSNS
40
18.9%
NZ_NNBP01000005.1:
Lassopeptides: CG747_RS46885_lassopeptide
8
GGPTGPVQDPLAPFDC
23
GG V++ AP+DC
1
GGDDTGVENKRAPYDC
16

#### MIBiG 4.0 matches for allorf_0109701_0109913

13.5%
BGC0002150.2 (MBO0654592.1):
Lasso peptide: triculamin
25
QPGPRHRGNALRA
37
+PG RG +R
5
KPGDGIRGKGVRG
17
allorf_0111999_0112211
Leader:
MGRSAILAG
Core:
RPTCFQGPRRGRAASASHVQRMSLVEAQNRAAPTAPVTPSLIRASLSSATPVSGQRSASSR
Core with dehydrations:
RPDhbCysFQGPRRGRAADhaADhaHVQRMDhaLVEAQNRAAPDhbAPVDhbPDhaLIRADhaLDhaDhaADhbPVDhaGQRDhaADhaDhaR

#### antiSMASH-DB 4.0 matches for allorf_0111999_0112211

100.0%
NZ_CP027862.1:
Lanthipeptides: allorf_0111999_0112211_lanthipeptide
1
RPTCFQGPRRGRAASASHVQRMSLVEAQNRAAPTAPVTPSLIRASLSSATPVSGQRSASSR
61
RPTCFQGPRRGRAASASHVQRMSLVEAQNRAAPTAPVTPSLIRASLSSATPVSGQRSASSR
1
RPTCFQGPRRGRAASASHVQRMSLVEAQNRAAPTAPVTPSLIRASLSSATPVSGQRSASSR
61
11.5%
NZ_CP015591.1 and 15 others:
NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide
Lanthipeptides: A7A70_RS27550_lanthipeptide
34
TAPVTPSLIRASLSSATPVSGQRSASSR
61
T P TP+++ A++++ + +SR
7
TTPATPTIVEATIAATVSICPTTKCTSR
34

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
No hits above weak threshold.
Weak hits (4):
MexT
Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 17.88 out of 21.84
Confidence: weak
MexT
Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.38 out of 21.84
Confidence: weak
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 17.54 out of 27.78
Confidence: weak
LexA variant 1
Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 22.04 out of 29.65
Confidence: weak
Lanthipeptides
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

C3B71_RS00410 - Class II
  Cleavage pHMM score: -6.80
  RODEO score: 0
  Monoisotopic mass: 4046.2 Da
  Molecular weight: 4048.7 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4066.7 Da N = 1
    4084.7 Da N = 2
    4102.8 Da N = 3
C3B71_RS16245 - Class II
  Cleavage pHMM score: -6.00
  RODEO score: 0
  Monoisotopic mass: 4148.1 Da
  Molecular weight: 4150.5 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4168.5 Da N = 1
    4186.5 Da N = 2
    4204.5 Da N = 3
    4222.5 Da N = 4
allorf_0094367_0094588 - Class II
  Cleavage pHMM score: -5.70
  RODEO score: 0
  Monoisotopic mass: 5046.7 Da
  Molecular weight: 5049.9 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    5067.9 Da N = 1
allorf_0097945_0098112 - Class II
  Cleavage pHMM score: -0.50
  RODEO score: 0
  Monoisotopic mass: 3434.5 Da
  Molecular weight: 3436.8 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3454.8 Da N = 1
    3472.9 Da N = 2
    3490.9 Da N = 3
    3508.9 Da N = 4
allorf_0098227_0098397 - Class II
  Cleavage pHMM score: -1.90
  RODEO score: 0
  Monoisotopic mass: 2890.5 Da
  Molecular weight: 2892.4 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2910.4 Da N = 1
    2928.4 Da N = 2
    2946.4 Da N = 3
    2964.4 Da N = 4
allorf_0109463_0109555 - Class II
  Cleavage pHMM score: -3.80
  RODEO score: 0
  Monoisotopic mass: 1582.8 Da
  Molecular weight: 1583.8 Da
  Number of bridges: 1
allorf_0109479_0109712 - Class II
  Cleavage pHMM score: -5.80
  RODEO score: 0
  Monoisotopic mass: 2835.3 Da
  Molecular weight: 2837.1 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2855.1 Da N = 1
    2873.2 Da N = 2
allorf_0109556_0109681 - Class II
  Cleavage pHMM score: -3.90
  RODEO score: 0
  Monoisotopic mass: 2267.1 Da
  Molecular weight: 2268.7 Da
  Number of bridges: 1
allorf_0109701_0109913 - Class II
  Cleavage pHMM score: -3.10
  RODEO score: 0
  Monoisotopic mass: 3915.0 Da
  Molecular weight: 3917.4 Da
  Number of bridges: 1
C3B71_RS16245 - Class II
  Cleavage pHMM score: -6.00
  RODEO score: 0
  Monoisotopic mass: 4148.1 Da
  Molecular weight: 4150.5 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4168.5 Da N = 1
    4186.5 Da N = 2
    4204.5 Da N = 3
    4222.5 Da N = 4
allorf_0094367_0094588 - Class II
  Cleavage pHMM score: -5.70
  RODEO score: 0
  Monoisotopic mass: 5046.7 Da
  Molecular weight: 5049.9 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    5067.9 Da N = 1
allorf_0097945_0098112 - Class II
  Cleavage pHMM score: -0.50
  RODEO score: 0
  Monoisotopic mass: 3434.5 Da
  Molecular weight: 3436.8 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3454.8 Da N = 1
    3472.9 Da N = 2
    3490.9 Da N = 3
    3508.9 Da N = 4
allorf_0098227_0098397 - Class II
  Cleavage pHMM score: -1.90
  RODEO score: 0
  Monoisotopic mass: 2890.5 Da
  Molecular weight: 2892.4 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2910.4 Da N = 1
    2928.4 Da N = 2
    2946.4 Da N = 3
    2964.4 Da N = 4
allorf_0109463_0109555 - Class II
  Cleavage pHMM score: -3.80
  RODEO score: 0
  Monoisotopic mass: 1582.8 Da
  Molecular weight: 1583.8 Da
  Number of bridges: 1
allorf_0109479_0109712 - Class II
  Cleavage pHMM score: -5.80
  RODEO score: 0
  Monoisotopic mass: 2835.3 Da
  Molecular weight: 2837.1 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2855.1 Da N = 1
    2873.2 Da N = 2
allorf_0109556_0109681 - Class II
  Cleavage pHMM score: -3.90
  RODEO score: 0
  Monoisotopic mass: 2267.1 Da
  Molecular weight: 2268.7 Da
  Number of bridges: 1
allorf_0109701_0109913 - Class II
  Cleavage pHMM score: -3.10
  RODEO score: 0
  Monoisotopic mass: 3915.0 Da
  Molecular weight: 3917.4 Da
  Number of bridges: 1
allorf_0111999_0112211 - Class II
  Cleavage pHMM score: -3.10
  RODEO score: 0
  Monoisotopic mass: 6100.3 Da
  Molecular weight: 6103.8 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    6121.8 Da N = 1
    6139.9 Da N = 2
    6157.9 Da N = 3
    6175.9 Da N = 4
    6193.9 Da N = 5
    6211.9 Da N = 6
    6230.0 Da N = 7
    6248.0 Da N = 8
    6266.0 Da N = 9
    6284.0 Da N = 10
    6302.0 Da N = 11
    6320.1 Da N = 12
    6338.1 Da N = 13
    6356.1 Da N = 14

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---

NZ_CP027862.1 - Region 2 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,039,357 - 2,060,502 nt. (total: 21,146 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
binding site
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Transferases: acyltransferase phosphorylase
C3B71_RS08465: thiamine-phosphate pyrophosphorylase

smcogs
  SMCOG1280: thiamine-phosphate pyrophosphorylase

C3B71_RS08530: acyltransferase

smcogs
  SMCOG1141: acyltransferase

Ligases: synthetase
C3B71_RS08490: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000677.5 |  | 0.42 | terpene | cyclooctatin | Streptomyces melanosporofaciens
BGC0001911.3 |  | 0.38 | terpene | raimonol | Streptomyces anulatus
BGC0000643.3 |  | 0.37 | terpene | carotenoid | Brevundimonas vesicularis
BGC0002309.2 |  | 0.37 | terpene | cattleyene | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000936.5 |  | 0.37 | other (other) | pyocyanine | Pseudomonas aeruginosa PAO1
BGC0002578.2 |  | 0.37 | other (other) | gaburedin A, gaburedin B, gaburedin C, gaburedin D, gaburedin E, gaburedin F | Streptomyces venezuelae ATCC 10712
BGC0000634.3 |  | 0.37 | terpene | carotenoid | Brevundimonas sp. SD212
BGC0001456.3 |  | 0.37 | terpene | isorenieratene | Streptomyces argillaceus
BGC0001910.4 |  | 0.36 | terpene | cyslabdan A, cyslabdan B, cyslabdan C | Streptomyces cyslabdanicus
BGC0000678.5 |  | 0.36 | terpene | pentalenolactone | Streptomyces avermitilis MA-4680 = NBRC 14893

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000677.5 |  | 0.42 | terpene | cyclooctatin | Streptomyces melanosporofaciens
BGC0001911.3 |  | 0.38 | terpene | raimonol | Streptomyces anulatus
BGC0000643.3 |  | 0.37 | terpene | carotenoid | Brevundimonas vesicularis
BGC0002309.2 |  | 0.37 | terpene | cattleyene | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000936.5 |  | 0.37 | other (other) | pyocyanine | Pseudomonas aeruginosa PAO1
BGC0002578.2 |  | 0.37 | other (other) | gaburedin A, gaburedin B, gaburedin C, gaburedin D, gaburedin E, gaburedin F | Streptomyces venezuelae ATCC 10712
BGC0000634.3 |  | 0.37 | terpene | carotenoid | Brevundimonas sp. SD212
BGC0001456.3 |  | 0.37 | terpene | isorenieratene | Streptomyces argillaceus
BGC0001910.4 |  | 0.36 | terpene | cyslabdan A, cyslabdan B, cyslabdan C | Streptomyces cyslabdanicus
BGC0000678.5 |  | 0.36 | terpene | pentalenolactone | Streptomyces avermitilis MA-4680 = NBRC 14893

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP
diterpene precursor |  | GGPP | C20 | acyclic | PP
sesterterpene precursor |  | GFPP | C25 | acyclic | PP
triterpene precursor |  | HPP | C30 | acyclic | PP

Genes with terpene domains:
C3B71_RS08490: PT_FPPS_like
Domain 1 (46 - 379): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: unknown

Reactions:
  IPP, DMAPP → FPP
  IPP, DMAPP → GGPP
  IPP, DMAPP → GFPP
  IPP, DMAPP → HPP

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 18.58 out of 23.79
Confidence: medium
AbrC3
Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 18.16 out of 18.16
Confidence: strong
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 23.58 out of 30.11
Confidence: medium
Additional weak hits (3):
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 17.50 out of 27.78
Confidence: weak
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 17.38 out of 28.19
Confidence: weak
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 22.10 out of 30.11
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
GFPP | Geranylfarnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
HPP | Hexaprenyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
AbrC3 | Antibiotic production activator
CelR | Cellobiose uptake repressor
IolR | Regulator of the inositol catabolism