LOCUS       NZ_CAOJCM010000001     23974 bp    DNA     linear   CON 27-FEB-2024
DEFINITION  Paenibacillus sp. JJ-100 isolate CIP112173 NODE_1, whole genome
            shotgun sequence.
ACCESSION   NZ_CAOJCM010000001
VERSION     NZ_CAOJCM010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. JJ-100
  ORGANISM  Paenibacillus sp. JJ-100
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Paenibacillaceae; Paenibacillus.
REFERENCE   1  (bases 1 to 1461466)
  AUTHORS   Criscuolo,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2023) INSTITUT PASTEUR, 25-28 Rue du Dr Roux,
            75015 Paris, France
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/27/2024 01:59:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,059
            CDSs (total)                      :: 4,954
            Genes (coding)                    :: 4,927
            CDSs (with protein)               :: 4,927
            Genes (RNA)                       :: 105
            rRNAs                             :: 8, 8, 11 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 4, 8, 11 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 27
            CDSs (without protein)            :: 27
            Pseudo Genes (ambiguous residues) :: 0 of 27
            Pseudo Genes (frameshifted)       :: 8 of 27
            Pseudo Genes (incomplete)         :: 22 of 27
            Pseudo Genes (internal stop)      :: 1 of 27
            Pseudo Genes (multiple problems)  :: 4 of 27
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:23:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 230502
            Orig. end                         :: 254476
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CAOJCM010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23974
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..23974
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23974
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13974](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13974
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(182..195)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.65"
                     /tool="antismash"
     misc_feature    complement(269..284)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.84"
                     /tool="antismash"
     gene            945..3425
                     /locus_tag="PQG66_RS01165"
                     /old_locus_tag="PAECIP112173_00231"
     CDS             945..3425
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007725828.1"
                     /locus_tag="PQG66_RS01165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00231"
                     /product="EAL domain-containing protein"
                     /protein_id="WP_272034208.1"
                     /transl_table=11
                     /translation="MEHIHGTYNLQLVILSYIIASLSSYVALDLAGRVSLTSGRARHWW
                     IACGAVSMGLGIWSMHFVGMLAFVLPIHVSYSTDIIMVSVLLAIAASGVALNFARRESH
                     KIARLVLAGLLMTIGITSMHYVGMEAMSIPVTYKPTLVSLSVLVAAVASFAALWLMFYF
                     NRRDSKLSWVYKMGSGFIMGLGIAGMHYTGMEAARFHQARIIPDHLSRQVEPEMLAYLI
                     TAGSFVTIGLTLFGNFINQRMSLKDQRIRESEQWYQALYHNHSDAIISVDRAGVIKGIN
                     AAVTTITGYTEKRVIDYPVEQILKHLDPQCESIHNACKWDDQEVEQQLFMAKMRNGRDE
                     LLDLSIAVIPVIIDETHVGSHILIKDITEETQAQEIIRHQALQDPLTGLYNRRKLDEVL
                     ANTIHICKENEARFAVMVMDIDRFKMINDSLGHSIGDIFLKEVSSRITSTIEASYPQAA
                     SNVTLARMGGDEFTMVVTGEQATEKHIVQLAEQIVEAIQQPYRLQENDFYVTTSIGIAM
                     YPEHGDVADDLIKHADSAMYEVKKNGKNGYQFYTAQLDSELYERIELEGYLRKALERNE
                     MVLYYQPQIRTQDGQMIGVEALIRWQHPIKGLLAPDVFIPLAEETGLIYEIGNWTLREA
                     CRQMKAWHASDGPRIPVSVNLSSQQFHQPNLVEQVQNALSETGLEAKYLELEITESMMM
                     DAAVSTAILNELSALGVKISLDDFGTGYSSLSYLKHFPIHKLKIDRSFVTDITESHSDQ
                     AIVATIISMAQNLQMEVIAEGIETKGQLDILMQNECKEIQGYYFSRPLPASEVENSFFV
                     PWRLFEESNSVVHS"
     gene            3623..3856
                     /locus_tag="PQG66_RS01170"
                     /old_locus_tag="PAECIP112173_00232"
     CDS             3623..3856
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015846288.1"
                     /locus_tag="PQG66_RS01170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00232"
                     /product="hypothetical protein"
                     /protein_id="WP_272034211.1"
                     /transl_table=11
                     /translation="MNFSLKAPDGTVIESYEKDHKEFIRIAGLEYEVYNPVDELDSDPE
                     IRQMIEASEKDIEQGELYSTDDLIQRVKRGEL"
     gene            3857..4138
                     /locus_tag="PQG66_RS01175"
                     /old_locus_tag="PAECIP112173_00233"
     CDS             3857..4138
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]"
                     /GO_function="GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]"
                     /GO_process="GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PQG66_RS01175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PAECIP112173_00233"
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_272034213.1"
                     /transl_table=11
                     /translation="MKVQWTATAMNRLRQIKSEHFSEQETMEYKINLIRRIEQKVVTMG
                     TMMPSREYHNTYYCIVDRYVVSYKVMDSGEYYVITSFKHSAMNRKYRF"
     gene            complement(4248..5684)
                     /locus_tag="PQG66_RS01180"
                     /old_locus_tag="PAECIP112173_00234"
     CDS             complement(4248..5684)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309457.1"
                     /locus_tag="PQG66_RS01180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00234"
                     /product="SpoVR family protein"
                     /protein_id="WP_272034216.1"
                     /transl_table=11
                     /translation="MTDEIRELEYAIAEIMEIADGFGLDYYPMRYEICPSDIIYTFGAY
                     GMPTRFSHWSFGKTFHKMKMQYDFGLSKIYELVINSNPCYAFLLDGNSLIQNKLIVAHV
                     LAHCDFFKNNARFSKSNRNMVDSMAATADRISNYEMEYGTEAVESFIDAVLAIQEHVDP
                     QLIKPRRLDKQRYMEMKIREQRGEKAPKPEGQYDDLWSLDNLQIEEKPADSIQVHHFPP
                     EPEKDIMWFIQEFSEVLTDWQRDIMSMMREEMLYFWPQMETKIMNEGWASYWHQRIIRE
                     LDLSSEDTIEFAKLNSSVVQPSRQSLNPYYLGLKIFEDIERRWDQPTREEQERWGRQPG
                     QGRAKMFEVREFDSDTSFIRNYMTKKLTEDLDLYVFEKKGPDWKITDKSWENIRDQLVF
                     SRINGGSPYLVVQDADYLRTGELVLKHQYEGIELDLKYMERTLPYLYRLWGRTVHVETR
                     VEEKPIWFTYDGKKHHRKFL"
     gene            complement(5681..6847)
                     /gene="yhbH"
                     /locus_tag="PQG66_RS01185"
                     /old_locus_tag="PAECIP112173_00235"
     CDS             complement(5681..6847)
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yhbH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370159.1"
                     /locus_tag="PQG66_RS01185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00235"
                     /product="sporulation protein YhbH"
                     /protein_id="WP_272034218.1"
                     /transl_table=11
                     /translation="MSNSHQPYSFVVSREDWSLHRKGYQDQQRHQQKVKDVIKQNLPDL
                     ITEENIIMSDGQQIIKVPIRSLDEYRFVYNYQKQKHVGQGDGDSQVGDVIGRDPASQKP
                     GKGEKAGDQPGHDIVEAEISIEELEDILFAELELPDLKQKDKDLIETHTVVFNDIRKKG
                     MQSNIDKKRTILENLRRNATTGNPGIHHISPDDLRYKTWEDKIIPQSNAVIIAMMDTSG
                     SMGSFEKYCARSFFFWMTRFLRRQYEKVDIVFLAHHTEAKEVTEEEFFTRGESGGTICS
                     SVYMKALEIIDQRYPPSSYNIYPFHFSDGDNLTSDNERCVKLIGELMKRSNMFGYGEVN
                     QYNRSSTLMSAYRHIKMDQFMYYVIKEKGEVYKALRSFFQKREGGSLG"
     gene            7103..8437
                     /locus_tag="PQG66_RS01190"
                     /old_locus_tag="PAECIP112173_00236"
     CDS             7103..8437
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015846352.1"
                     /locus_tag="PQG66_RS01190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00236"
                     /product="MFS transporter"
                     /protein_id="WP_272034220.1"
                     /transl_table=11
                     /translation="MDKRAVKAWIMYDWANSAYATTVLAAVLPVFYASIAAATLDKDTA
                     ASYLAYTHSVGMLCVALLTPLLGTLADLSGRKGDFLRVFAITGIMATLGFSVIGEGDWL
                     LASVLLVLSTIGFAGGNTFYDAMLPDLVPAERRDMVSSKGYAYGYIGGGLLLAINLLMI
                     QQPGWFGMSSTLAGTRLAFISVSLWWLLFSLPIFRHAPRRPASAELPASWIGYTKVGIH
                     RLRQTFGQIRRFPQLLRMLLAFWFFNDGINTIILMATIYGTSIGIGTSDLMLALLLTQF
                     IGFPCTLLLGAWAQRWGAKQVLLVSLSIYICIVILGYFMTQALHFYILAGLVGVVQGIS
                     QSTARSLFSNLMPSGRTGEYFGFVNITGKFASIFGPFVFGYVGQITGSSRWGILSLIFF
                     FVAGIVFLLTVNVQKGIHDARLADQEELERGMEMLGKGKGVHFTG"
     gene            8736..10001
                     /locus_tag="PQG66_RS01195"
                     /old_locus_tag="PAECIP112173_00237"
     CDS             8736..10001
                     /EC_number="2.8.2.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280289.1"
                     /locus_tag="PQG66_RS01195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00237"
                     /product="sulfotransferase"
                     /protein_id="WP_272034222.1"
                     /transl_table=11
                     /translation="MIDTQGNGLVFLLCIPRSGSSLSTVMLQNHSRIFATQEMWFLMNL
                     VDLSKADSRAYGGSSIIRQFYQAMVSEDVFEKACRSFALEIYNGFLEGSGADFIVDKSP
                     RYYYMLEWLDRLFPQSRRIHLQRNPLSIAASFKKVDRHTGESFDLIQSLNHPKLHMKAI
                     DLTLGLTRLNDYFAEPHPLAYELKYEQLVMKPQEEMEKLCGFLGLSYEQGMEQYGQFVH
                     STKADMFYSMGVGDPFLSSHQEAHQGSVNNWKNILDRQEVEWYCRVLGADLFERMGYGE
                     QLQEAERWTGVQFQAEPDQEVLERLQQQLTAATDCRWQQNYRLRAPIDGVENRASLQSS
                     PDSQEAAKIDPTLAAMATIRQLQAALRAADQRLERGYSERERLKKQLDSAQSKLKRIKS
                     WIPFGHQISAWASQRKIVRGGK"
     gene            10001..11932
                     /locus_tag="PQG66_RS01200"
                     /old_locus_tag="PAECIP112173_00238"
     CDS             10001..11932
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689564.1"
                     /locus_tag="PQG66_RS01200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00238"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_272034224.1"
                     /sec_met_domain="GATase_7 (E-value: 1.8e-23, bitscore:
                     79.1, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 4.9e-19, bitscore:
                     65.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIVHRDGQQALWEDSWRLYASLGHIPADTTGVWKGDEAFL
                     SCHAQWITLESVNEKLPLHDEDSRLIITADAILDNREQLADQLQISRAELSTLADSQLI
                     LRAYQRWGEQVAGHLLGDFVFAIWDERRHTLFAARDITGMRAFYYRHDGSRFAFCTLMK
                     PLLELEGVQKSLDESWLSEFLAIPDMHDSVDIHSTVYRGVNQLPSAHTLTFRNGKIELK
                     HYHRWDDVEPLRLKSDDEYVEAFRDVFSQAVGSRLRTHRQVAAALSGGLDSGAVAGFAS
                     GTLRNQGKQLHAYSYVPVPDFTDYTPKTLLADERPFIRSTISHVGNIAENYLDFEGRSP
                     LSEVDTWLNMMEMPYKYFENSFWIRGFYEKASEQDAGILLTGARGNFTISWGPALDYYA
                     SLLKSGRYFRWFREMQQYSERTGMAFSRIARITGRKAFPDWFKGNNKATVQPAGAQLIH
                     PELAQRTGVMERLKSILVLQGGARADALQVRADKFNNLAIANKNGAVATKCSLRYRVWE
                     RDPTSDPRVIRFCLSVPIEQYVRHGTDRSLIRRATSPELPDKVRLNQRVRGVQPADWLH
                     RILPDWQAFTSEMQALCSDSRVAGILNTDRIRTALANFPSPKAELASHPDLRLMMHSLI
                     VYRFIQKF"
     gene            11969..12106
                     /locus_tag="PQG66_RS01205"
                     /old_locus_tag="PAECIP112173_00239"
     CDS             11969..12106
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689562.1"
                     /locus_tag="PQG66_RS01205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00239"
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_272034226.1"
                     /transl_table=11
                     /translation="MQNEKKEWQAPVLEVLDVNETMAGVGYRQIDWITAHDADMYDPTS
                     "
     gene            12247..13191
                     /locus_tag="PQG66_RS01210"
                     /old_locus_tag="PAECIP112173_00240"
     CDS             12247..13191
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PQG66_RS01210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PAECIP112173_00240"
                     /product="aldolase"
                     /protein_id="WP_272034228.1"
                     /transl_table=11
                     /translation="MPVHYEAYGLRWLSQIPMPELQSAPLDAETEQGAVDVRIETFDLT
                     GLWKSWDVGNDNFVARDGCLFFRIEDTGLFLMEQGQRIVISPISGADPKKVRLFILGTC
                     MSVIMMQRGILPLHGSAVVIDQRAYAFVGHSGAGKSTLSAALASRGYPLLTDDVVALTW
                     DAEGRAIVSPGYPQQKLWQPSLDGFGMDQQNYATVHAEITKYAIPVQHYFHERAVPLAG
                     IYELVPRPDHGSGSVHLEEVIGLERLHVLCSHTFRAGLVTRQGLAQWLFETVSKLSASV
                     EISRISRTGQDFTAFEMVERIINHIRKGVQVGI"
     gene            13188..13487
                     /locus_tag="PQG66_RS01215"
                     /old_locus_tag="PAECIP112173_00241"
     CDS             13188..13487
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689560.1"
                     /locus_tag="PQG66_RS01215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00241"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_272034230.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.6e-27,
                     bitscore: 91.7, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 7.4e-19, bitscore: 64.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAITPIHANDVISRKEGNLVSDMGGEKVMMSIASGKYYNLGSTG
                     GRIWELIAEQRKLEELIEALAVEYDIQPEQCREQVVPFLEHLSREGLIDISRGV"
     aSDomain        13227..13469
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PQG66_RS01215_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.40E-29"
                     /identifier="RREFam002.1"
                     /label="PQG66_RS01215"
                     /locus_tag="PQG66_RS01215"
                     /protein_end="94"
                     /protein_start="13"
                     /score="91.7"
                     /tool="antismash"
                     /translation="SRKEGNLVSDMGGEKVMMSIASGKYYNLGSTGGRIWELIAEQRKL
                     EELIEALAVEYDIQPEQCREQVVPFLEHLSREGLID"
     gene            13492..13974
                     /locus_tag="PQG66_RS01220"
                     /old_locus_tag="PAECIP112173_00242"
     CDS             13492..13974
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689559.1"
                     /locus_tag="PQG66_RS01220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00242"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_272034232.1"
                     /sec_met_domain="PF13471 (E-value: 2e-25, bitscore: 85.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRKIKAYFSLPAPVRQLMWEAYILLGWARIQKARSFAKIAPGLG
                     TPMVETPMTGLNRTQVVEIRNISKAVMLASKYTLWESQCLVMAIAAMKMLERRHIASTL
                     YMGTARNKQGQLMAHAWLRSGKLIVTGADTMDQYTVVGVFGKGCPEKGSGEIVYDA"
     gene            14021..15160
                     /locus_tag="PQG66_RS01225"
                     /old_locus_tag="PAECIP112173_00243"
     CDS             14021..15160
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.4"
                     /locus_tag="PQG66_RS01225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00243"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_272034235.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.5e-63, bitscore:
                     210.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLRDDLTDLTSKEMTSRLHDMDWPLFVQLVYHHRLYSVIYVRL
                     KQMNLPSVPQTVMESLKQQYTINTFRMLQLTAEMEQVCGAFRERGIRTITLKGPALAHD
                     LYGDVSMRTSKDLDILIPVQEVEAAERILIGLGYQCKEGERSLTVRSWKWREHHICYIH
                     PEKRTQVEIHWRLNPDSGRETDFELLWKRSRFSSYTQTPVRMLEREDLWVYLVTHGARH
                     GWFRLRWLLDMDQMIRTMPLDTKKIERRLKAEGRLSIGSQTLHLASGLLHTPLSDDYLS
                     IMAMSNRAGQRLARAGALFMNDMLDSPAELPNYQSYLFSLRSVRQKWFFFIERLYPSTW
                     DVHQLPLPRSLYFLYFPLRPFLWFWRRFKKSTMTERGKV"
     gene            15157..16998
                     /locus_tag="PQG66_RS01230"
                     /old_locus_tag="PAECIP112173_00244"
     CDS             15157..16998
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689557.1"
                     /locus_tag="PQG66_RS01230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00244"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_272034237.1"
                     /transl_table=11
                     /translation="MISELKYFMQKLHHVSGPILYWNLLAMISIGLMEGIGIYMLVPML
                     SLIGVFEMGSTGLHLSWLSSILRQFSENSQLILVLFAFVFILSGQAWMQRLQTIRNTRI
                     QQQFIRTLRMETYSAILRAQWSFFLQKRKSDFNHILTTELARVSQGTNLILQTVASLIF
                     TTIQIGLAFWLSARLTTLVLICGVLLFILLRKFVRRAKQIGDQTSEYSQHYYNGITEHF
                     NGIKDIKSNMLEHSHIRWFERLCRQIEYNVVQFSQLNTGTQLIHRMSAALIIATFIYLS
                     LQVMSVPPASLLLIILIFSRLWPRFTAIQSNLEYISSMLPAFRMVRELQLQTEKSREIN
                     EEFSIDPEPEPKRGASVAPPIVPMDPVEAITCENVYFRYEDSDTYALKNVQSSIPARGM
                     TAIVGKSGAGKSTLIDLIMGLIKPESGQILIDGKALSEEQLLNWRSSIGYVSQDPFLFH
                     TSIRENLRLVDPNASEEQMWRALQFSSSASFVQRLPQGLDTIIGDRGIRLSGGERQRLV
                     LARTMLRNPSVLVLDEATSALDSENEQHIHEALERLKGHVTIIVIAHRLSTIRTADRVI
                     VLEEGRVIQEGGYQQLSSDSSGTFSKLLHMQAGAAGQ"
     gene            complement(17148..17786)
                     /gene="cysC"
                     /locus_tag="PQG66_RS01235"
                     /old_locus_tag="PAECIP112173_00245"
     CDS             complement(17148..17786)
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689556.1"
                     /locus_tag="PQG66_RS01235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00245"
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_272034239.1"
                     /transl_table=11
                     /translation="MSNEERNITWQTSSLSRQDRERFNGHRSRTVWFTGLSGAGKSSIA
                     FALESYLSEQGVRCYVLDGDNVRHGLNRDLGFTSSDRQENLRRIGEVSKLMVDAGLLVL
                     SAFISPHEEDREMVKQLFEPEDFIEIYVRCSIEECERRDPKGLYKKARNGEIPHFTGIS
                     APYDIPKSPSLIIDTEQYNIAEAVQQIVEHLQHIGALNLPVQTDSALTY"
     gene            17938..18351
                     /locus_tag="PQG66_RS01240"
                     /old_locus_tag="PAECIP112173_00246"
     CDS             17938..18351
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689555.1"
                     /locus_tag="PQG66_RS01240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00246"
                     /product="hypothetical protein"
                     /protein_id="WP_272034241.1"
                     /transl_table=11
                     /translation="MSDNITNIQVGFKCPDCGQEVSLYFIQEQVNTVRCGGCQRAYTLM
                     KPTIGDEILLNWEQEALYHKLRAERSEQDNHSMSALIIKVIELLTWRDQGDGQTRAIQT
                     VKEWLADSGKPLTLLELFHQPTSIKHENKRNSR"
     gene            18447..19226
                     /gene="pdaA"
                     /locus_tag="PQG66_RS01245"
                     /old_locus_tag="PAECIP112173_00247"
     CDS             18447..19226
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pdaA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689554.1"
                     /locus_tag="PQG66_RS01245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00247"
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="WP_272034243.1"
                     /transl_table=11
                     /translation="MKRLVLYLLLGLLMISTLASQAEASPINGAYHFGFKKSQNGQLPS
                     IDQEGFKSILEHNQAIFLGDTKQKELYLTFDNGYENGFTPAILDVLRTKKVPAAFFVTG
                     HYLKDQPELVKRMAAEGHIVGNHSWSHPDMTRISNGQIKEELEKVKSEVNRLTGQQATF
                     LRPPRGIFNNRTLAESYAQGYINVFWSVAYKDWDTNVQRGPQYAHQQVLKQLHPGAVIL
                     LHSVSKDNTDALGSIIDEARKQGYVFKSLEELKTKTY"
     gene            complement(19449..20297)
                     /locus_tag="PQG66_RS01250"
                     /old_locus_tag="PAECIP112173_00248"
     CDS             complement(19449..20297)
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018753336.1"
                     /locus_tag="PQG66_RS01250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00248"
                     /product="DegV family protein"
                     /protein_id="WP_272034245.1"
                     /transl_table=11
                     /translation="MARIKIFADSTSDLAPEWIQQYDIGIVPLYVVFGDESLKDGEEIK
                     PEQLYERVSRDGSLPKTAAPSPADFMTAFQPYIEQGDDILYISLSSELSSTYQNALLAS
                     SEFPEGRISVVDSKNLSSGIGLMVMKAVHAAEQGQTLVQITERIEAMKSNVRTEFVIDT
                     LEYLYKGGRCSGMQNLIGSLLKIRPVIRVADGKMTPAYKVRGKREKALEQMLQNTLSNK
                     EQIDRDLVIVVHTMAEEDALNLQKTLQEQTGARVELTTAGCVICSHCGPKTTGIIYSTT
                     H"
     gene            complement(20407..20874)
                     /locus_tag="PQG66_RS01255"
                     /old_locus_tag="PAECIP112173_00249"
     CDS             complement(20407..20874)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PQG66_RS01255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PAECIP112173_00249"
                     /product="hypothetical protein"
                     /protein_id="WP_272034246.1"
                     /transl_table=11
                     /translation="MDHQNTNNSEMNNTSSHSGYSDPNALGNTFPPDLPGTPAERLKHS
                     GPGISSFIVGLVALLGHITTFVLLFLALNNTLQLLGSSLSREDLAFHPAVVLSSLAFLV
                     CLVLNLSGVILGIIGLVLKNRRKVFAIIGLILNALFILLFVGLILREIYLT"
     gene            21054..21440
                     /locus_tag="PQG66_RS01260"
                     /old_locus_tag="PAECIP112173_00250"
     CDS             21054..21440
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689551.1"
                     /locus_tag="PQG66_RS01260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00250"
                     /product="DUF423 domain-containing protein"
                     /protein_id="WP_272034248.1"
                     /transl_table=11
                     /translation="MQRRWMMVGAILTMLSVAIGAFGAHMLKDRIGASAIATYETGVQY
                     HMIHALGLLIIGLTAGQLGASMKLRWAARLLFAGIIIFSGSLYILSISGIKILGAITPI
                     GGVAFIIGWLLFALDVWQRGKNSF"
     gene            complement(21568..22113)
                     /locus_tag="PQG66_RS01265"
                     /old_locus_tag="PAECIP112173_00251"
     CDS             complement(21568..22113)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007127357.1"
                     /locus_tag="PQG66_RS01265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00251"
                     /product="hypothetical protein"
                     /protein_id="WP_272034251.1"
                     /transl_table=11
                     /translation="MKQTLSNQDEIGYLFNVDILIKSRSNALALQSLIEFINKEEQVAD
                     FRIHSGIELGKIIETMLETRKITSDSDPKKQESSPSPGEKLTSTKPNKAVDSASKKKTT
                     SDTSHVADASSFDAWIESLIKENRLTRIVVNNKNGKHQSIPCRILNFDRDNSVVTIYHV
                     DEKQVYTFRTNEIDEFLT"
     gene            22385..22687
                     /locus_tag="PQG66_RS01270"
                     /old_locus_tag="PAECIP112173_00252"
     CDS             22385..22687
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349131.1"
                     /locus_tag="PQG66_RS01270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00252"
                     /product="YunC family protein"
                     /protein_id="WP_272034253.1"
                     /transl_table=11
                     /translation="MVTMEPIVVGEHVLVGVEVKLPKTTLLTINTSKGYIMCGALDVGL
                     LNEKLGDRKIVAARAVGVRTLEQLLHAPMESVTTEAQAMGITVGMTGVEALLKMI"
     gene            complement(22797..23858)
                     /gene="mtnA"
                     /locus_tag="PQG66_RS01275"
                     /old_locus_tag="PAECIP112173_00253"
     CDS             complement(22797..23858)
                     /EC_number="5.3.1.23"
                     /GO_function="GO:0046523 -
                     S-methyl-5-thioribose-1-phosphate isomerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /gene="mtnA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689544.1"
                     /locus_tag="PQG66_RS01275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PAECIP112173_00253"
                     /product="S-methyl-5-thioribose-1-phosphate isomerase"
                     /protein_id="WP_272034256.1"
                     /transl_table=11
                     /translation="MTTPEHQPLSSLNWKKDKLEMLDQRLLPETILMLKLYTPEEVWEA
                     IHSMKVRGAPAIGIAAAFGVVLGAKAYDGIAIQGWLDHVKSVCAHLATSRPTAVNLFWA
                     LDRMMQKANQAAESGLSLQEGTDALEVEALLIQKEDEEVCRMIGEHALPLFEDGMGVLT
                     HCNAGGLATAKYGTATAPMYLAQERGIHLKVFADETRPVLQGARLTAFELQQAGIDVTL
                     LCDNMAGMVMSKGWVQAVIVGTDRVAANGDVANKIGTYSLAVLAKAHNIPFYVASPLST
                     IDLSTSSGDLIPIEERAAEEVTEGFGKRTAPQGIKVFNPAFDVTPNEYVTAIITEKGIV
                     RAPFQENLAALFT"
ORIGIN
        1 attattgtct ggaacgatac aaataatgag cagccacaga agaaagaaag tcgaggcaag
       61 ctcaagttag gccctgagtt gaaacaagtt aaagtcacgt acggaactcc tgtggtggat
      121 ggcaaggaag ataagctatg gaaaaaagct gcatccatca caacggatgt aactgttgtg
      181 ggcaattccg gtgccaaggc taaggcgaag ctgctgtggg atgaaaagta tctctacgtg
      241 ctcgctaatg tcaatgatcc tctactcagt aaaaaaagcg ctaatgccca tgaacaagac
      301 tccattgagt tattcattga tctgaacaag aatcagacga gtagctatga ggatgatgat
      361 gcgcagtacc gaattaattt cgacaatgaa gcttcttttg gaggtaacgc ccgcaaagag
      421 cagttcaaat cgaccgccct tctgaccaaa gatgggtata tgatcgaggc tgccattcca
      481 cttgagaatg tgaactccaa gcagagcaaa tggattggtt tcgatcttca ggtgaatgat
      541 gacggtgcgg gggatggcaa acgaagcagt gtcttcatgt ggagtgatcc ttcaggcaat
      601 tcgtaccgcg acacgtccgg atttggtagc ctgtttctgg tgaaaaaata ggtctgcgga
      661 tagaactatg aacccgttat atgatgaaga gttgcagcgg agaagccagg tacagctgag
      721 ttatgcttct ggaaataagt gttgattttc gcagctggga cgtttagact atatacatcg
      781 attatatgcg ggtttcaaat gtatgccaaa cggtttatga ctgagtcgct aatctcgaag
      841 tcaaatgata cggagcgagt gcctgtcatc cagacagtgc gctcgcttct ttttcatatt
      901 ttacaacata catatgagat ctcccggctg aaaggacaga gtgagtggag cacatacatg
      961 gcacctataa tctacaactt gttattttat cctatattat tgcgtcgtta tcctcttatg
     1021 tagcacttga tcttgcaggt cgtgtatcac tgacaagcgg aagagcccgt cactggtgga
     1081 ttgcttgcgg ggctgtttct atggggctag gcatatggtc aatgcacttt gtcggcatgc
     1141 ttgcgtttgt tctgcctatt cacgtctctt attctacaga tataatcatg gtatctgttc
     1201 ttctggcgat tgccgcatca ggagttgcac tgaactttgc gagacgcgag tcccataaaa
     1261 tcgccagact ggtgcttgca gggctattga tgacgatcgg tattacctct atgcattacg
     1321 tggggatgga agcgatgtcc attccagtga catacaaacc gacacttgtg tctttatcgg
     1381 ttctggttgc agcggtggct tcctttgcgg cgctgtggct tatgttttat tttaaccgac
     1441 gggattctaa actgagctgg gtttataaaa tgggtagtgg cttcattatg gggttgggca
     1501 ttgcaggtat gcattacacc ggcatggagg cggcccgttt ccaccaagcg agaatcattc
     1561 ctgaccattt aagcagacaa gttgaaccag agatgcttgc ttatctgatt acagcaggct
     1621 catttgtgac gattggcctc acattgtttg gtaattttat taatcagcgg atgtccctga
     1681 aggatcagcg tattcgcgag agtgaacaat ggtatcaagc gttgtatcat aatcattcag
     1741 atgccattat ctctgtggac agagcaggtg ttattaaagg gatcaacgca gctgtaacta
     1801 cgattacggg atatacggag aaaagggtga ttgactatcc ggtcgaacaa attcttaagc
     1861 atttggatcc ccagtgtgag agtattcata atgcttgcaa atgggacgat caggaagtgg
     1921 agcaacagtt attcatggcc aagatgagaa atggtcgcga tgaactcctt gacttaagta
     1981 ttgctgtcat tccagttatc atagatgaaa ctcatgtagg cagtcatatt ctcattaaag
     2041 atataacgga ggagacgcag gctcaggaga taatacgcca tcaagcgctg caagatccac
     2101 tcacagggtt gtataatcgg cgcaagttgg atgaagtgct ggcgaatacc atacatattt
     2161 gtaaagaaaa cgaagcccga tttgctgtga tggttatgga catagaccgc ttcaaaatga
     2221 ttaacgactc attgggtcat tctatcggtg atatattcct taaggaagtt agtagccgaa
     2281 ttacaagtac cattgaagct tcttatccac aagcggcttc taatgtgacg ctcgcccgaa
     2341 tgggcgggga cgagtttacc atggtagtca ctggtgaaca ggcgacggag aagcacatag
     2401 ttcaacttgc agaacagatt gtcgaagcga tccagcaacc ttatcgtcta caggaaaatg
     2461 atttttacgt tacaaccagt atcggtattg ccatgtatcc tgagcatggg gacgtagcgg
     2521 atgatctgat taaacatgcg gattctgcca tgtatgaagt gaagaaaaat ggaaagaacg
     2581 gctaccagtt ctatacggct cagctggact ctgagctcta cgaacgaatt gagctggaag
     2641 gttatctgcg aaaagcgctg gaacggaatg aaatggtgct gtattatcag ccgcagatca
     2701 ggacacagga tggccagatg attggagttg aagctctgat ccgttggcag catcccatta
     2761 aaggattgtt agcacctgat gtatttattc cactggccga ggagacgggt ctgatctatg
     2821 agattggcaa ctggacgctt cgtgaagcct gcaggcagat gaaggcctgg catgctagcg
     2881 atggcccacg tatcccggtg tctgtgaact tatccagcca gcaatttcac caacctaacc
     2941 tggtggagca agttcagaat gcattaagcg agacaggact ggaagccaaa tatctggaac
     3001 tggaaattac cgaaagtatg atgatggatg cagcggtatc cacagctatt ctgaacgagc
     3061 tttccgctct gggtgtgaag atcagtctgg atgatttcgg tacgggatac agttcactaa
     3121 gctatctgaa acacttcccg atccacaaat tgaagatcga tcgttccttt gtcacggata
     3181 ttaccgagag tcatagcgat caagcgatcg tggcaaccat tatttcgatg gcacagaatc
     3241 ttcagatgga agtgatcgca gaaggcattg aaacgaaggg acagctggat attctgatgc
     3301 aaaatgaatg caaggaaatc caaggttatt atttcagccg gcctctaccg gcaagtgaag
     3361 tggaaaacag tttctttgta ccctggcgtt tgtttgaaga aagtaattct gttgtacatt
     3421 cctaaaaagg ctaagcggca agttctcgat ttgtatcgcg aacttgccgc tttattttgt
     3481 ggtatacgct cttctttcaa tatttgtaaa ttgtccgaaa gtcattattt catggctgag
     3541 ttgcaacacg gttgtatgct ataattcaga ttaaggttct tattagcagg tgtagcgata
     3601 tcatcgaagg aggttgcaag gaatgaactt tagtctgaaa gctcctgatg gcaccgtcat
     3661 tgaatcctat gagaaagatc ataaggaatt cattcgaatt gccggcttgg aatatgaagt
     3721 gtataatccg gtggatgagt tggattccga tccggaaata agacaaatga ttgaagcatc
     3781 cgagaaagac atcgagcaag gtgaactgta ttcaacagat gacctgattc aacgggtgaa
     3841 gcgtggtgag ctgtaattga aggttcaatg gaccgcaacg gcgatgaacc gacttcgtca
     3901 gatcaaaagt gagcattttt cagagcaaga aacgatggag tacaaaatca atctgattcg
     3961 acgtatagaa caaaaagtgg taacgatggg gacaatgatg ccttcccgtg agtaccacaa
     4021 tacatattac tgtatcgtgg atcgttatgt tgtctcttat aaagtcatgg acagcggcga
     4081 atactatgtg atcacttcat ttaagcatag tgcgatgaat cgtaaatata gattttaatc
     4141 tctgacgaac ttatatataa catgccaaag cggcaagttc tcgaattgta tcgggaactt
     4201 gccgtttttt gtttttccaa cctatatccg tactgcatca ctccagctta caaaaacttg
     4261 cggtgatgct ttttgccatc ataggtgaac cagattggtt tttcttctac acgagtctcc
     4321 acgtgaacag tacgccccca gagtcgatac aggtacggaa gggtgcgttc catgtatttt
     4381 agatctagct caatgccctc atattgatgt ttcaacacga gttcgcccgt gcgcagatag
     4441 tccgcgtcct gcacgaccag atatggggag cccccattga tacgcgaaaa tacaagctgg
     4501 tcgcggatgt tctcccacga cttgtcggtg attttccagt ccggtccctt tttctcgaac
     4561 acatagagat cgaggtcctc ggttaacttc ttggtcatgt agttccggat gaaggaagta
     4621 tccgagtcga attcgcgcac ctcgaacatt ttggctctac cctgacctgg ctgccgcccc
     4681 caacgttcct gctcctcacg tgtgggctga tcccagcggc gttcgatatc ttcgaagatt
     4741 ttcagtccta ggtaatatgg attcagactc tgtctggagg gttgcacaac ggaagaattc
     4801 agcttggcaa attctatcgt atcctcacta ctcaggtcta gctcgcgtat aatacgttga
     4861 tgccagtagg aggcccagcc ttcgttcata attttcgttt ccatctgtgg ccagaaatag
     4921 agcatttcct cccgcatcat actcataatg tcccgctgcc agtcggtgag cacctcggag
     4981 aactcctgga taaaccacat aatatctttc tctggttccg gcgggaaatg atgcacctgt
     5041 atgctgtccg caggcttttc ttcgatctgc agattatcga gggaccacag gtcatcgtat
     5101 tgaccttccg gtttaggcgc tttttcacca cgctgttcgc gaattttcat ctccatgtac
     5161 cgctgtttgt ctaggcgccg cggtttgata agctgcgggt ccacatgttc ttgaatggcg
     5221 agtaccgcgt cgatgaagga ttcgaccgcc tctgtaccat actccatctc atagttgctg
     5281 attcgatccg ccgtagcggc catgctatcg accatgttgc ggttggattt ggagaagcgg
     5341 gcattgtttt tgaaaaagtc gcagtgcgca agaacgtgcg ctacgattaa tttgttctga
     5401 attagagagt tgccatccaa caggaaggcg tagcaaggat tagagttgat tacgagttca
     5461 taaattttgc taagtccaaa atcatattgc attttcattt tgtgaaatgt tttaccaaag
     5521 ctccaatggc tgaacctcgt gggcatgccg taagcgccaa aggtgtagat aatatccgac
     5581 gggcagatct cgtagcgcat cgggtaatag tcgaggccga atccatcggc aatctccata
     5641 atttcagcaa tagcgtattc cagttcgcgg atctcatcgg tcatcccagg ctgcctcctt
     5701 ctcttttttg aaaaaagctg cggagcgctt tgtacacttc tcctttttcc ttgatgacgt
     5761 aatacataaa ctgatccatc ttaatatggc ggtaggcaga catcagtgta ctgctgcggt
     5821 tgtactgatt cacttcaccg tatccaaaca tgttgctgcg cttcataagt tcaccaatca
     5881 atttcacgca acgctcatta tccgaggtca ggttatcgcc atccgagaaa tggaacggat
     5941 aaatattgta gctggaaggc ggataacgtt gatcaataat ctccagtgcc ttcatatata
     6001 cagaggagca gatcgtgccg ccgctctcgc cgcgagtgaa aaattcctct tccgtcactt
     6061 ctttggcctc cgtgtggtga gccaggaaca caatgtcgac tttttcatac tgacgccgta
     6121 ggaaacgggt catccagaag aaaaagctac gcgcgcagta tttttcaaac gatcccatcg
     6181 acccggatgt atccatcatg gcgataataa ccgcattgga ctgaggaatg atcttatctt
     6241 cccaggtctt gtaacggaga tcgtccggac tgatgtgatg gatgcctgga ttgcctgttg
     6301 tggcattgcg gcgcaggttc tccagtattg tacgtttctt gtcgatgttg gactgcatgc
     6361 cctttttgcg aatatcgttg aagaccacgg tatgtgtctc gatcagatct ttatccttct
     6421 gtttcagatc aggcagttcc aattcggcaa acagaatatc ttctaattcc tcaatactga
     6481 tctccgcttc aacaatatcg tgaccgggct gatcgccggc tttttcgccc tttcctggct
     6541 tctgagatgc cggatcacgg ccaatgacgt cgccaacctg gctatccccg tctccttggc
     6601 caacatgttt ttgcttctgg tagttataca caaaacggta ctcatccaga ctgcggattg
     6661 gtaccttaat gatttgttgt ccatcggaca tgataatatt ttcttcggta atcagatcag
     6721 gcagattttg cttaatgaca tctttcacct tttgctgatg gcgctgctgg tcctggtacc
     6781 ctttgcggtg aagcgaccaa tcttcccggg atacgacgaa cgagtaaggc tggtgtgaat
     6841 ttgacatgta ggcacccccc attgattacg cggcacagtt tggcctgtcg gtaattaagt
     6901 atattcacgg gctggggcga tatgtgatgc gatctcaact aaaatgaatg aattgcgtgg
     6961 attcgcatcg ggattagctg gagaaagtac atgccgaaat tttacaaaaa tgatgatcaa
     7021 ctgtgagcaa tttcctttac aatagagaaa atagactcat tttgaacatc gaaccctgat
     7081 gtgtgtaaag gacggatgaa gtgtggataa acgtgcagta aaagcctgga ttatgtatga
     7141 ctgggccaat tcggcttatg caacaacggt gctggcagct gtgctgcctg tattctatgc
     7201 ttctatagct gcggcaacct tggataagga tactgcggct tcctacctcg cctatacaca
     7261 ttccgtcgga atgttgtgtg tcgcgctatt aacaccgctg ctgggaactt tagcggacct
     7321 gtctgggcga aaaggagatt tcctgcgcgt atttgcgata acggggatca tggcaactct
     7381 gggattcagc gtcattggag aaggggattg gctacttgca tctgtcctgc tggtgttatc
     7441 cacgattggg tttgctggcg ggaatacgtt ctatgatgcc atgctaccgg atctggttcc
     7501 tgcggagcga agggatatgg tatcttccaa agggtacgcc tatggttata tcggcggagg
     7561 gctgctgctg gccatcaatc tgttaatgat tcagcagccg ggctggtttg gcatgtcaag
     7621 tacacttgca ggcacgaggc ttgcattcat ttcggtttcg ctgtggtggc tgttgttttc
     7681 cctcccgatc ttccggcatg caccgagaag accggcttcc gctgaactgc cagcttcctg
     7741 gataggttat acgaaggttg gtatacatag attaaggcag accttcggac agatcagacg
     7801 ttttccgcag ctgcttcgaa tgctgcttgc tttctggttt ttcaacgacg gaatcaatac
     7861 gattattctg atggcaacca tctacggaac cagcatcggt attggcacgt cggatctgat
     7921 gctcgcgctg ctgctcacgc agttcatcgg atttccgtgt acactgcttc tgggcgcgtg
     7981 ggcacagcgg tggggagcga agcaagttct gctggtgagt ctaagtatct acatctgtat
     8041 cgttattctt ggatatttta tgacgcaagc tcttcatttt tatatcctcg caggattagt
     8101 tggcgttgtg caggggataa gtcaatcgac ggcacgttcg ctgttcagca atctgatgcc
     8161 atctggacga accggtgagt actttggatt tgtaaatatt actggcaagt tcgcctcgat
     8221 ctttggacca tttgtattcg gttatgtggg acagatcacg ggttcttccc gttggggtat
     8281 tctgtcgctg atcttctttt ttgtagcagg tattgttttt ttattgacag tgaatgtaca
     8341 aaaaggcata catgatgccc gattggccga ccaggaagag ctggagcgtg gcatggaaat
     8401 gctggggaaa gggaaaggcg ttcattttac tggttaagta ttctttcgtt atcgttgttc
     8461 atcaaatcat actcctcgct tcaggtactg ttcatgacag agcagatccc tggagctttt
     8521 ttacgttgag ccgtattccg caagaggtga gcaaataaat tatgaaaagg tgaaaataaa
     8581 agattgacat gatacatttt gtatcataga gtaaagatgt aaatacatat tgtatcttag
     8641 agtgtcgaaa tgacctgtca tatgcaggcc tatgttactc cggtcgatcc gatcccacat
     8701 cttattctta taaatataca gaggagaggc tgccattgat agatacgcaa ggaaacggac
     8761 ttgtcttttt gttatgcatc ccccgcagtg gcagttcgtt atccaccgtt atgctgcaaa
     8821 accatagtcg tatattcgct acgcaagaga tgtggtttct gatgaatctc gtcgatttgt
     8881 ccaaggctga ctctcgcgct tacggtggta gttctatcat ccgtcaattt tatcaagcga
     8941 tggtgtccga agatgttttc gaaaaggcat gtagaagctt tgctcttgaa atatacaatg
     9001 gattcctgga agggagcgga gcagacttca tcgtagataa atctccgcgt tattattata
     9061 tgcttgaatg gctggatcgg ttgtttccgc agtccagacg cattcatctt cagcgtaatc
     9121 ccctttctat agcggcatcc tttaaaaaag tagatcgcca taccggcgaa agttttgatc
     9181 tcattcagag tctgaatcat ccgaagctcc atatgaaagc tattgatctg acgttaggct
     9241 taactcgtct aaatgattat ttcgcagagc ctcatccact tgcatatgaa ctcaagtatg
     9301 agcagctggt catgaaacca caggaggaaa tggagaagtt atgtggcttc ctaggacttt
     9361 cttatgaaca aggtatggag cagtatggac agtttgttca cagtacgaaa gctgacatgt
     9421 tctacagcat gggtgttggg gatcctttcc tttcatctca tcaggaagcc caccaaggtt
     9481 ctgttaacaa ctggaaaaat atactagatc ggcaagaggt tgaatggtat tgtcgtgtcc
     9541 tgggagccga tctgttcgaa cgtatgggat acggtgaaca gctgcaagaa gccgaacgat
     9601 ggacgggagt ccagttccaa gctgagccag atcaggaagt gctggagcga cttcagcagc
     9661 agctgacggc ggcaacagat tgtcgttggc agcagaacta ccgactaaga gcgccaatag
     9721 atggcgtgga gaatcgtgct tcacttcaga gcagtccaga tagccaggaa gctgcaaaga
     9781 tcgacccaac actagcagcg atggctacga tccggcagtt gcaggcagct cttcgtgcag
     9841 cggatcagcg gctggaacga gggtattcgg aacgagagcg tttgaagaag caacttgatt
     9901 ccgcccaaag caagcttaag cggatcaaat catggatacc attcggtcat caaatcagcg
     9961 catgggcatc tcaacgcaaa atcgttcgag gaggaaagta atgagtgcca tagccggaat
    10021 tgtacatagg gatggtcagc aggcgctatg ggaggacagc tggcggttat acgcaagtct
    10081 tggacatatc ccagcagata caacgggggt atggaaaggg gatgaagcct tccttagctg
    10141 ccatgcccag tggattacgc tagagtctgt caacgaaaaa ttgcctttac atgatgaaga
    10201 tagtcgatta atcatcactg ccgatgccat tctggataac cgggagcaac tggcagatca
    10261 gttgcagatt tcaagagctg agctgtctac gctggcagac agtcagctga ttctacgggc
    10321 atatcagcgc tggggagaac aggtggctgg tcatctgtta ggcgattttg tatttgcaat
    10381 ctgggatgaa cggcgccata ccttgtttgc cgcaagggat atcacaggca tgagggcgtt
    10441 ctactatcgt catgatggtt cacggtttgc cttttgtacg ttgatgaagc cattgcttga
    10501 gcttgaaggt gtccagaaat cactcgacga aagctggtta tccgaattcc tggctattcc
    10561 ggatatgcat gactcggtag atattcattc cacggtttat cgtggcgtaa atcagcttcc
    10621 atctgcacac acattgacgt ttcggaacgg gaagatcgaa ctgaagcatt accatcgctg
    10681 ggatgacgtt gaaccgcttc ggctcaaatc ggatgatgaa tatgtggaag cttttcgcga
    10741 tgtgttcagt caagctgtag gttcgcgcct gcgaacccac agacaagtgg cggcggcatt
    10801 aagtggtgga ttggattctg gagccgttgc cggttttgca tctggaacgc tccgtaatca
    10861 ggggaaacag cttcatgctt acagctatgt acctgttccc gactttacgg attacacgcc
    10921 caagacgtta cttgctgacg agcggccatt cattcgttcc acgatcagtc acgtaggtaa
    10981 tatcgcggag aactatctgg atttcgaagg acgcagcccg ctcagtgaag tggatacatg
    11041 gctcaatatg atggagatgc cttataaata ctttgaaaat tcattctgga tccgtggatt
    11101 ctatgagaaa gcgagtgagc aggatgcagg tattctgctc acaggcgccc gtggtaattt
    11161 tacgatctcg tggggacctg cgcttgacta ttatgccagt ttgctgaaaa gcggaaggta
    11221 tttccgctgg ttccgggaga tgcagcagta cagcgagcgt acaggaatgg cattctcaag
    11281 aattgcccgc atcacaggac gtaaagcctt ccctgactgg tttaaaggga acaacaaggc
    11341 gacagtacag cctgcaggcg cgcaattaat tcatcctgaa ttagcccaaa gaacaggggt
    11401 aatggagcga ctcaaatcta ttctggtgtt gcagggtgga gcacgagccg atgcccttca
    11461 ggtacgagct gacaagttca acaatttggc gatagccaat aagaatgggg ctgtcgctac
    11521 aaaatgttct cttcgctatc gggtatggga acgtgacccg acgagtgatc caagagtcat
    11581 ccgattttgt ctctctgtac cgattgagca gtatgtcaga catggcacgg atcgatctct
    11641 gattcgccga gctacttcac cggaattgcc cgataaggta aggctgaacc agcgtgttcg
    11701 gggcgtacag cctgcggact ggctgcatcg tattttgcct gactggcaag catttacctc
    11761 agagatgcag gccttgtgtt ctgacagccg ggttgccggc atattaaaca cggatcgcat
    11821 tagaacagcc ctagctaatt ttccaagtcc taaggccgaa ctggcgtcac acccggattt
    11881 gcgcctaatg atgcacagtt tgattgtata ccgatttatt cagaaatttt aacctgcagc
    11941 agagctcata tgaaaggagg tgaaaacaat gcaaaacgaa aaaaaggaat ggcaagcacc
    12001 tgtacttgag gtattggatg tgaacgaaac aatggcaggg gtagggtaca gacaaatcga
    12061 ctggattact gcacacgatg ccgatatgta cgatccaacg tcttaattct gttcatattc
    12121 caagcatgtc catacttaaa gggcggaaat gcagacatct cagctttttc gcctccgccc
    12181 taatattgag caaatgaata tcagggcttt ttttcatatc taaaaacgaa ggaggccccc
    12241 ttattgttgc ctgtgcacta tgaagcttac ggtttgcgct ggttgagtca gatcccgatg
    12301 cccgagttgc aaagtgcacc tctggatgcc gaaacggagc agggtgcagt tgatgtacgg
    12361 atcgaaacgt tcgatctgac gggactgtgg aagagctggg atgtgggcaa cgacaacttt
    12421 gtagcgcggg acggttgtct ttttttcaga atcgaagata caggattatt tttaatggaa
    12481 cagggtcaac gcatcgtaat ctcgccaata tcgggagctg atccgaaaaa agtaaggctg
    12541 tttatcctcg ggacatgcat gtccgtgatt atgatgcagc gcggcattct tccactgcac
    12601 gggagtgcag tagttattga tcaaagggct tacgcgttcg tcgggcattc tggcgcagga
    12661 aagtctacat tatctgcagc gctcgcatct cgtggatatc ctcttctcac cgatgatgtg
    12721 gtggccttga cttgggatgc cgaaggaaga gccatcgtgt caccgggata tccacagcag
    12781 aaattatggc agcccagtct ggatggtttt ggtatggatc aacagaacta cgccacggtg
    12841 cacgctgaaa tcacgaaata tgccattccc gttcaacact attttcatga gagagcggtg
    12901 cctttagctg gaatctatga gcttgtaccc cggccagatc acggatcggg atcggttcat
    12961 ctggaagagg ttatcggtct cgaacgtctt cacgtgctgt gctctcatac ctttcgtgct
    13021 ggactggtga cacggcaggg acttgctcaa tggttgttcg aaacggtatc caaactctca
    13081 gctagtgtgg agatcagcag gatcagcaga acagggcaag actttacagc atttgagatg
    13141 gtggaacgaa tcatcaatca tatacgcaaa ggagtgcaag taggaatatg acagctatta
    13201 cacccatcca tgcgaatgac gtgatatcac ggaaggaagg taatctggtt agtgatatgg
    13261 gcggcgagaa ggtgatgatg agcattgcct ccggtaaata ttacaatctg ggcagcaccg
    13321 gtggacgcat ctgggaactc atcgcagagc agcgtaagct ggaggaattg attgaggcgc
    13381 ttgctgtaga atacgatatc caaccggagc aatgccgtga acaggttgtg ccttttttgg
    13441 agcacctctc acgtgaagga ttaatcgata tttcccgcgg agtctaggaa gatgtttcgg
    13501 aaaataaaag cgtatttctc gcttccagct ccggtaaggc aattgatgtg ggaagcttac
    13561 atcctgctgg gatgggcacg aattcagaag gcaaggtcgt ttgccaagat tgctccggga
    13621 ctcggaacgc ctatggtgga aacacctatg actggtttga atcgaactca agtggtggag
    13681 atcagaaata tctcaaaagc agttatgctt gccagcaaat atacgttatg ggaaagccag
    13741 tgtcttgtca tggctatagc tgcgatgaaa atgttggagc gtcgtcatat cgcaagtacg
    13801 ttatatatgg gcacggcacg gaataagcaa ggacaactga tggcacacgc ctggctacga
    13861 agtggcaagc tgatcgtaac tggagcagat acgatggatc aatatacggt cgtcggcgtg
    13921 tttggtaaag ggtgtcctga gaagggatct ggagagattg tctatgacgc atgaaactga
    13981 actgtattct acaaggtttc cgaaggagct taagttcatc ttgagcctgc ttagagatga
    14041 tctgacggat ctaacttcta aggagatgac gagccggctg cacgatatgg attggccact
    14101 gtttgtacag cttgtgtacc accatcgtct gtattcggtc atctatgtga gattaaaaca
    14161 gatgaatctt ccgtctgttc cccagacggt aatggagagc ttgaaacagc agtatacgat
    14221 caacacgttt cgtatgttgc aactcacagc tgaaatggag caagtatgcg gggcgtttcg
    14281 ggaacggggg atccgcacga ttacactaaa agggcctgct ctggcgcatg acctgtacgg
    14341 tgatgtttct atgcgaacct ccaaagatct ggatattttg attccagtcc aagaggtcga
    14401 ggcagcagaa cgtattctca tcgggcttgg ttaccagtgc aaggagggtg agagatcact
    14461 taccgttcgc agttggaagt ggcgggagca tcacatttgt tatattcatc ccgagaaacg
    14521 gactcaagtg gagatccatt ggaggcttaa tcccgactcc ggccgagaaa cagactttga
    14581 gttattatgg aaacgcagtc gcttcagctc ttatacccag acacctgtac gtatgctcga
    14641 aagagaggat ctatgggtgt atttagtgac acatggtgca aggcatggat ggttcagatt
    14701 gcggtggtta ctggacatgg atcagatgat tcgtacgatg ccactggata caaaaaagat
    14761 agagcgacgt ctgaaagcag agggacgttt atccattggt tcccagacat tgcatcttgc
    14821 ttcgggcctg ctgcatacgc cgctgagtga cgattacctc tccatcatgg ctatgagtaa
    14881 ccgtgctggt cagcgattag cgagagccgg tgcgctgttt atgaatgaca tgctggatag
    14941 tccagcagag ttgccgaatt atcaatcgta tttgttttct cttcgaagtg ttaggcagaa
    15001 atggtttttc tttattgagc gtttatatcc gagtacttgg gacgtgcatc aactgccgct
    15061 tcctcgctct ctgtactttc tatatttccc gttacgtccg tttctctggt tctggcggcg
    15121 cttcaaaaaa agcacgatga cagagagggg aaaagtatga tctcagaact gaaatatttt
    15181 atgcaaaagc tgcatcatgt ctcggggccc attttatatt ggaatctgct ggctatgatc
    15241 tcgatcggtc taatggaagg aatcggcatc tacatgcttg ttccgatgct gagcttaatc
    15301 ggtgtttttg agatgggatc gacaggtcta catctatctt ggttaagctc tatacttcgc
    15361 caattctcag aaaatagtca attaatactt gttctgttcg cctttgtatt catcctctct
    15421 ggacaggcgt ggatgcaacg tctccagacg atccgcaata cccgtattca gcagcaattc
    15481 atacgaacgc tgcgtatgga aacctatagc gcgatcctta gagcgcagtg gtcttttttt
    15541 ctccaaaaac gaaaatccga ttttaatcat atattaacga ctgaacttgc ccgagtaagt
    15601 cagggaacca atctcattct gcagacggtg gcctcactga tttttacaac cattcagatc
    15661 ggtcttgctt tctggttatc tgccagatta acaacacttg tgctgatctg tggagtgttg
    15721 ctatttatcc tcctgcgcaa gtttgttaga cgcgctaaac agattgggga tcagacttcg
    15781 gaatattcac aacattatta taatggcatt accgagcatt ttaacggaat caaagatatc
    15841 aaaagtaata tgctggaaca ctcccatatc cgctggtttg agcgcttgtg cagacagatt
    15901 gaatataatg tggtgcagtt tagtcagcta aatacaggta cacagctcat tcataggatg
    15961 tcagctgcgt taattattgc gacgtttatt tatctatctc tacaggtaat gtccgtgcct
    16021 ccagcaagtc tgctattgat tatattaatt ttttcacgat tatggccgag gtttaccgcc
    16081 attcagtcca atctggagta cataagctcg atgctgcctg catttcggat ggtgagagag
    16141 ctgcaattac agacggagaa gagccgcgag atcaatgaag aattctcaat cgacccagaa
    16201 ccagaaccga aaagaggtgc gtccgttgct ccccccatcg ttccaatgga tcccgtggaa
    16261 gccatcacct gcgaaaatgt ttattttcgt tatgaagaca gcgacactta cgcattgaag
    16321 aacgtacaat catcgattcc agctcggggt atgacagcga ttgttggtaa atcaggggca
    16381 ggtaaaagca cattaattga tctgattatg ggtctaataa agcctgagag cggacagatc
    16441 ttgatcgacg gaaaagcctt gtcagaggag caactgttaa attggcgtag ttctatcgga
    16501 tacgtgtcgc aagatccctt tttgtttcat acaagtattc gtgaaaatct gcggctggtt
    16561 gaccctaatg caagtgagga acagatgtgg cgggcacttc aattttcttc ttcagcctca
    16621 tttgtacaga gacttcctca aggtctggat acgattatcg gcgatcgggg catacgtctt
    16681 tccggcggtg agcgtcagcg tctggtgcta gctcggacca tgctgcgcaa tccttccgtg
    16741 ctggtactgg atgaagcaac aagtgcactg gacagtgaaa atgaacagca cattcatgaa
    16801 gcgctcgaac gactgaaagg acacgtcact attattgtca ttgcccatcg attatctacc
    16861 attcgaaccg cagatcgagt catcgttctg gaagaagggc gtgtcattca agagggtgga
    16921 tatcagcagt tatcatccga ctcatctggg acgtttagca agctgcttca tatgcaggca
    16981 ggtgcagcag ggcaatagaa gacatatgag cttaagaaag gagtgaagag tgaagtaaaa
    17041 caacaaagga gtaaaataaa acaagaaagg cgtaccgcaa agggacgcct tttctatcat
    17101 tcatttttag tagattgtaa tttgtagatt agtagctctg aggtctacta atatgtcagg
    17161 gcagaatcgg tctgtacagg aagatttaaa gcgccgatgt gttgcagatg ttctacgatc
    17221 tgttgaacag cttctgcaat gttatattgc tctgtatcga tgatgagtga aggggacttc
    17281 ggtatgtcat aaggggcgga gattcctgta aagtgaggga tctcaccatt gcgtgccttt
    17341 ttgtagagac ctttcggatc acgccgttca cattcctcaa tagaacagcg cacatagatt
    17401 tcgatgaaat cttctggttc gaataattgc ttaaccatct cccggtcttc ttcatgagga
    17461 gagataaacg ccgagagtac aagcagtcca gcgtcgacca tcaacttgga cacttctcca
    17521 atgcgccgta gattttcttg ccgatccgac gaagtaaacc caagatcgcg attcaaccca
    17581 tgacggacat tatcaccatc aagcacataa caacgaacac cttgttcaga caagtaactc
    17641 tccagtgcaa aagcaataga tgacttaccc gcgccggata aaccagtaaa ccacactgtg
    17701 cggctgcgat gtccgttgaa tctttcccga tcctgtctac ttaaactcga tgtttgccag
    17761 gtaatattgc gttcttcatt tgacatgtca tcccgcctct tctaacctca tgatttgtat
    17821 aatattttaa catatttact agattgtagc atatagaaat gttctgcaaa gatacagctt
    17881 gaatgttctg tatatcgggt atagatgtgt atacatagag agcaggaggg caatacgatg
    17941 agtgataaca ttaccaatat acaagtgggc ttcaaatgcc ctgattgcgg gcaggaagta
    18001 agtttatatt ttatacagga acaagtgaat acggttcgct gtggtggatg tcagcgtgct
    18061 tatacactca tgaaaccaac gataggcgat gagattttgc tgaattggga gcaggaggca
    18121 ctgtaccata agctgcgtgc agaacgttct gagcaggata atcacagtat gtcggcactc
    18181 atcattaaag tgattgagct cttgacctgg cgggatcaag gagatgggca gacccgcgca
    18241 atccagacag tcaaagaatg gctggctgac agcggcaaac cgctgacttt gctggagctt
    18301 tttcatcaac cgacatccat caaacacgaa aataaacgga actcgcgcta aataattaca
    18361 taacatatac gttcctgtgg catattacct gaaggtgttt gtgaaccttg aaacaaaccg
    18421 aatattcagg aacaggagcg gataacatga agcggttggt tctatatctg ctgctcggct
    18481 tgttaatgat tagcacgctg gcatctcagg cagaggcatc tcctattaac ggagcttatc
    18541 actttggctt caaaaaaagt caaaatggtc agctaccttc cattgatcag gaaggattca
    18601 agtccatatt ggaacataat caagccatat ttttgggaga taccaaacaa aaagaactgt
    18661 atttaacttt tgataatggc tatgagaatg gattcacccc tgcaatattg gatgtgttac
    18721 gaacaaaaaa agtgcctgct gctttctttg tcacgggaca ttatttgaag gatcagcctg
    18781 agctagttaa acggatggct gccgaagggc acatcgtggg taaccattca tggagccacc
    18841 ctgatatgac ccgaatttcc aacggacaaa tcaaagagga actggaaaag gtgaaatccg
    18901 aagtgaaccg ccttacggga caacaagcta cttttttacg tccccctcga ggtattttta
    18961 acaatcgtac actcgctgag agttatgccc aaggatatat taatgtgttc tggtctgtag
    19021 cctataagga ttgggacacc aatgttcagc gaggtccaca atatgctcat cagcaagtgt
    19081 tgaaacaact tcatccggga gctgtcattt tgctgcattc tgtatccaaa gataatacgg
    19141 acgcacttgg ctctattatc gatgaggctc gcaagcaagg ttatgtattc aaaagcctcg
    19201 aagagttgaa aacaaaaacc tattaattcg gacaagttat tcgattaatg gatcagacag
    19261 gtgaatgtac caaatgagct aaagtctttt acaggtacag atacaggtac ggaacaggta
    19321 aagttcaaca taatcagaag ggcatgccaa gcgaatctgc ttagcatgcc ctttatgagt
    19381 ttgacacagt catcaaagta tacatagatt gcagttgatg gcctgattca atatatacaa
    19441 tgtcacatct agtgtgtggt gctataaata atgcccgttg ttttcggacc acaatgactg
    19501 caaatgacgc agcccgccgt ggttaattca acgcgtgccc cggtctgttc ttgcaatgtt
    19561 ttttgtaagt taagcgcgtc ttcctcagcc atagtgtgaa cgacaatcac taggtcacga
    19621 tcaatctgtt ccttattact gagtgtgttt tgtaacatct gctccagtgc cttctcccgc
    19681 ttacctcgta ctttataagc aggggtcatt ttaccatcag ctactcgaat gacaggacga
    19741 atcttaagca gactgccaat caggttttgc atcccggagc agcgtccacc tttatataag
    19801 tattcgagag tatcgatgac aaattctgta cgaacgttcg atttcatggc ttcgatacgc
    19861 tctgtaatct gaaccagagt ctgcccctgt tctgcagcgt gaacagcttt cattaccatc
    19921 aggccaatac cggaggagag gtttttggaa tctacaacgg agatgcgtcc ctccggaaat
    19981 tcagaactgg cgagcagggc attctggtat gttgaagaaa gttcagatga taaggagata
    20041 tacagaatat cgtccccttg ttctatgtaa ggttgaaatg cggtcatgaa atctgctggc
    20101 gaaggtgcag ctgtcttggg tagagaacca tcgcggctta cacgttcgta caattgctct
    20161 ggtttaatct cttctccgtc cttcagggat tcatcaccaa ataccacata caatggaacg
    20221 atgccgatgt cgtattgctg gatccattca ggggccagat cactagtact gtccgcaaaa
    20281 attttgattc gtgccatctt aatctccttt agaaaacaaa tatttgtcag ttacacataa
    20341 cgtgtaatag gcaagtatag gccgcctgag ttttattata aagaaccttg cctgttatgc
    20401 aaagcattac gtcaagtaga tttctctaag tatgagtccg acgaacagca gaataaatag
    20461 tgcattcaga atcaagccaa tgatcgcgaa taccttccgg cgatttttga gcactaatcc
    20521 aatgataccg aggataactc cagacagatt aagaaccaga cagacgagaa aagctagaga
    20581 ggacaggaca actgccggat gaaaagcgag atcctcgcgg ctgagtgacg agcccagaag
    20641 ttggagagtg ttgttcagag ctagaaaaag taaaacaaag gtcgtgatat gccctaaaag
    20701 tgctaccaac cctacgataa aactggatat tcccggtcct gaatgcttga gtcgctcagc
    20761 aggtgtgccg ggtaagtctg gcggaaacgt gttgccaagg gcattaggat ctgaataacc
    20821 ggaatgtgat gaggtgttgt tcatttctga gttgttcgtg ttttgatggt ccatagatga
    20881 ggactcctcc ttctaaatat tgtgatattc tgcggtggaa taaaagctat tacccgattt
    20941 accgtccagt gatagattgc gaaagtagat atccatacga tgtttctttt actttgggta
    21001 gtgaattcgc tacaatacat agtatcagaa acctttaaag ggagagagtg aacatgcagc
    21061 gtagatggat gatggttgga gccatattaa ccatgctatc ggtggcgatt ggtgcatttg
    21121 gcgcacatat gcttaaggac agaattggcg caagtgcaat agctacatat gaaacaggag
    21181 tgcaatacca tatgattcat gctctgggct tgctcattat tggattaacg gcaggccaac
    21241 tgggagcttc gatgaagctg agatgggcag cacgtctcct gtttgcagga attatcatct
    21301 tctcaggaag cctgtatatt cttagcatct caggtattaa gatcctggga gctattacac
    21361 ccatcggcgg cgtagcgttt atcattggct ggttgttatt cgcgctggat gtctggcaac
    21421 gaggcaaaaa cagtttctaa ccgcattctt atttataatg aaagaatagc ataataaaag
    21481 caacctgtgt cgaatgtcca gcattctaga acaggttgct ttttgagttg aattataaac
    21541 ttgcattgcc attgctagat ataagggcta tgtcaagaac tcatcaattt cgttggtacg
    21601 gaaagtgtac acttgtttct cgtccacgtg atagatggtt accacactgt tatcccgatc
    21661 aaagttaaga atacgacaag gaatgctttg atgtttgcca tttttgttgt tcacaacaat
    21721 tcgcgtgagc cgattttctt tgattaatga ttctatccag gcatcaaacg aactagcgtc
    21781 agcaacatgt gaagtgtcgg aagttgtttt tttcttagaa gcagaatcaa ctgctttgtt
    21841 tggcttagtg gaggttaact tttcaccagg tgatggtgag gactcttgtt tttttggatc
    21901 agagtcagag gtgattttcc ttgtctcaag catcgtttca atgattttgc cgagctctat
    21961 tccggagtga atccgaaagt ccgcaacttg ttcttctttg ttaatgaact cgatcaggga
    22021 ctgtagtgcc aatgcatttg aacggctctt aataagtata tcgacattaa ataaatagcc
    22081 gatttcatct tgattggata aggtttgttt cattcatccc agccccgtta aataatgtat
    22141 aagtaccaac gtactctagt atactatagc attaatatac tggaaatcat agaccaaagg
    22201 ggggggatgt gtattaaaat taaaggattt taatatttcc aaaatgggcc atcagaggat
    22261 gatgttgcag cgatgtctgt tttttataca tacttttgat tatgcacggc aggtgtccac
    22321 acagtgtttc gtcaaaaggc atacaaatat cgggatctgt tgaataggag ggaatctcga
    22381 tattatggtg acgatggaac ccattgtggt gggagagcat gtgctcgttg gggtagaggt
    22441 taaacttccc aagacgacat tgttaacaat taatacatct aaggggtata tcatgtgcgg
    22501 cgctcttgat gtggggttgc tgaatgagaa actgggtgac cgcaaaattg tggctgcgcg
    22561 ggctgtcggt gtgcgaacac tggagcaatt gcttcatgca ccaatggaat cagtgacaac
    22621 tgaggcgcag gctatgggca ttacagtagg aatgacaggc gtagaagcgt tgttaaaaat
    22681 gatctaaatc aagtttcagg ttacacatgt cacagtacga agaagaacaa aaaagggacg
    22741 aagtcggatg cgtccgtctt gtcccttctt actaaccccc aaagaaggcc ccggctttac
    22801 gtaaataaag cggcaaggtt ctcctgaaaa ggtgcacgaa cgatgccctt ttctgtaata
    22861 atcgcggtca cgtactcatt cggcgttaca tcaaaggctg gattaaatac cttgatacct
    22921 tgtggtgctg tgcgtttccc gaatccttcg gtcacttctt ccgcagcacg ttcctcgatc
    22981 ggaatcaaat ctccggaaga ggtggacaag tctatcgttg ataatggact tgctacatag
    23041 aacggaatgt tgtgggcttt agcgagtaca gcgaggctgt aagtaccaat tttgttagct
    23101 acatcgccat tcgcggctac ccgatccgta ccgacgataa cagcttgtac ccaccctttg
    23161 gacatgacca ttccagccat gttgtcacac agcagagtta catctattcc agcttgttgc
    23221 aactcaaatg ctgttaagcg ggccccttgc aggacagggc gcgtttcatc agcgaatact
    23281 tttagatgaa tcccgcgttc ctgagcgaga tacatcggag cggttgccgt accgtatttg
    23341 gctgtagcca gtccccctgc attgcagtga gtcagcacac ccatcccatc ctcaaacaaa
    23401 ggcagagcat gttctccgat catgcggcac acttcttcat cttccttctg aatcagcaat
    23461 gcttccactt caagcgcatc cgtgccttct tgcagactca ggccagattc agctgcttgg
    23521 ttagcctttt gcatcatgcg atctagtgcc cagaacagat taaccgctgt tggacgggag
    23581 gtcgccagat gtgcacatac ggacttaacg tgatccagcc agccttggat ggctatacca
    23641 tcataagctt tggcgcccag tacaacacca aatgctgcgg caataccaat ggcaggtgca
    23701 ccacgtactt tcatcgaatg gatcgcttcc cacacttctt caggcgtata tagtttcagc
    23761 atcagaatgg tttctggcag tagtcgctga tcgagcattt ctagcttgtc ctttttccag
    23821 ttaagcgaag acagaggctg atgttctggg gttgtcatgg gtgttcctcc gttcaataat
    23881 attagattta gactgtggta agagtagtag atactagatc aagcacctca ttgatcgtgt
    23941 ttacttggcg attattcttg ataagtgctt tacc
//
