MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
AEI70243.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000401.5 NRPS:Type I 72.0 99.6 798.0 2.83e-290
CAB15188.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000309.5 NRPS:Type I 70.0 98.7 756.0 6.3e-274
NPC94428.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002695.2 NRPS:Type I 69.0 97.2 748.0 7.46e-271
ABS75234.1 DhbE BGC0001185.5 NRPS:Type I 68.0 98.5 741.0 5.78e-268
QRK05499.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002324.3 NRPS:Type I+PKS 67.0 98.9 727.0 2.38e-262
AAG31128.1 MxcE BGC0001345.5 NRPS:Type I 65.0 98.0 715.0 1.35e-257
ABF86856.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002492.3 NRPS:Type I 66.0 98.0 712.0 1.88e-256
CBA63660.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000368.5 NRPS:Type I 65.0 97.8 667.0 1.42e-238
AGK13425.1 enterobactin_synthetase_component_E_(2,3-dihydroxybenzoate-AMP_ligase) BGC0002528.3 NRPS:Type I 60.0 98.1 638.0 2.72e-227
AAZ55904.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000359.5 NRPS:Type I 59.0 100.0 624.0 1.33e-221
WP_068925906.1 AMP-binding_protein BGC0002688.2 NRPS:Type I 60.0 99.3 613.0 5.76e-218
CAQ46282.1 putative_siderophore_specific_2,3-dihydroxybenzoate-AMP_ligase BGC0002689.2 NRPS:Type I 57.0 98.0 602.0 7.56e-213
AMK48234.1 salicylate-AMP_ligase BGC0001351.3 NRPS:Type I 56.0 98.3 599.0 7.07e-212
ABW70812.1 PchD BGC0002475.3 NRPS:Type I 56.0 98.0 597.0 4.19e-211
AEF33098.1 3-hydroxypicolinic_acid:AMP_ligase BGC0001039.5 NRPS:Type I+PKS 54.0 100.9 584.0 3.94e-206
RGP42811.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002696.2 NRPS:Type I 55.0 99.6 575.0 1.77e-202
BAH33406.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000371.5 NRPS:Type I 55.0 99.6 575.0 2.51e-202
QIE08740.1 salicylate-AMP_ligase BGC0002544.3 NRPS:Type I 54.0 98.9 571.0 5.25e-201
WP_141576284.1 AMP-binding_protein BGC0002686.2 NRPS:Type I 54.0 98.3 569.0 1.55e-200
MBD2892724.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002718.2 NRPS:Type I 55.0 98.7 566.0 3e-199
EFL06871.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000300.5 NRPS:Type I 54.0 98.0 556.0 1.73e-195
AGN74880.1 3-hydroxypicolinic_acid:AMP_ligase BGC0000459.5 NRPS:Type I+PKS:Trans-AT type I 53.0 98.9 553.0 6.69e-194
ACU36660.1 AMP-dependent_synthetase_and_ligase BGC0000392.5 NRPS:Type I 54.0 100.2 541.0 8.68e-189
AAO07759.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000460.5 NRPS:Type I 51.0 99.3 539.0 3.18e-188
AGE11892.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000366.5 NRPS:Type I 51.0 98.7 540.0 3.31e-188
ALK21567.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002678.2 NRPS:Type I 53.0 98.5 536.0 6.14e-187
ABU70375.1 hypothetical_protein BGC0001890.3 NRPS:Type I 53.0 99.1 531.0 1.95e-185
AFB35629.1 EsmD2 BGC0000935.5 other:aminocoumarin+PKS 51.0 99.8 524.0 3.77e-182
AAC45927.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002494.3 NRPS:Type I 50.0 98.9 523.0 4.78e-182
CAJ34366.1 putative_3-hydroxy-quinaldate-AMP-Ligase BGC0000445.5 NRPS:Type I 50.0 96.7 521.0 1.38e-181
QYA95658.1 AMP-binding_protein BGC0002676.2 NRPS:Type I 51.0 100.4 520.0 5.47e-181
KDQ70107.1 Triostin_synthetase_I BGC0001444.5 other:shikimate-derived 51.0 99.6 512.0 1.32e-177
ctg4_1 BGC0002017.3 NRPS:Type I 56.0 88.3 507.0 1.3e-176
AVR52609.1 AMP-dependent_synthetase BGC0002443.3 PKS 50.0 98.9 507.0 1.23e-175
EYT83445.1 Triostin_synthetase_I BGC0001213.5 PKS 47.0 100.0 506.0 2.68e-175
CAJ45636.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000454.5 NRPS:Type I 49.0 98.7 503.0 2.31e-174
CCA53797.1 Long-chain-fatty-acid--CoA_ligase BGC0001801.5 NRPS:Type I 49.0 98.9 501.0 1.43e-173
CAC17498.1 putative_AMP-binding_ligase BGC0000324.5 NRPS:Type I 49.0 102.2 498.0 4.51e-172
ALE27504.1 3-HPA:AMP_ligase BGC0001292.5 other:other 48.0 99.6 498.0 7.8e-172
BAH04171.1 AMP-binding_ligase BGC0000450.5 NRPS:Type I 49.0 98.7 496.0 1.08e-171
AET98914.1 putative_AMP-binding_ligase BGC0000415.5 NRPS:Type I 48.0 98.7 494.0 6.15e-171
MBE3202941.1 AMP-binding_protein BGC0002410.3 NRPS:Type I 46.0 105.2 496.0 1.76e-170
WP_069848012.1 salicylate_synthase BGC0002472.2 NRPS:Type I 49.0 97.8 508.0 3.36e-170
AAQ59159.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002679.2 NRPS:Type I 50.0 99.8 491.0 9.19e-170
AQZ26587.1 obafluorin_dimodular_nonribosomal_peptide_synthetase BGC0001437.5 NRPS:Type I 51.0 97.4 526.0 1.56e-169
ACY02013.1 enterobactin_synthase_subunit_E BGC0000343.5 NRPS:Type I 49.0 98.7 488.0 3.64e-168
ADE34495.1 SsfL1 BGC0000269.5 PKS:Type II+saccharide:hybrid/tailoring 48.0 101.3 484.0 8.91e-167
BAC16758.1 probable_2,3-dihydroxybenzoate-AMP_ligase_protein BGC0002474.2 NRPS:Type I 47.0 100.4 483.0 1.67e-166
BAE98151.1 putative_AMP-binding_ligase BGC0000339.5 NRPS:Type I 48.0 98.9 482.0 4.22e-166
AXG47413.1 salicylate_synthase BGC0002715.2 NRPS:Type I+PKS 50.0 95.2 496.0 1.12e-165
ABK38474.1 2,3-dihydroxybenzoate-AMP_ligase BGC0001502.4 NRPS:Type I 48.0 101.9 479.0 8.05e-165
WP_005009579.1 AMP-binding_protein BGC0002473.3 NRPS:Type I 47.0 100.4 479.0 8.6e-165
KJY85277.1 enterobactin_synthase_subunit_E BGC0002491.3 NRPS:Type I 49.0 101.1 478.0 2.93e-164
BAI63284.1 putative_peptide_arylation_enzyme BGC0000434.5 NRPS:Type I 48.0 98.7 475.0 2.29e-163
AAC73695.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002476.2 NRPS:Type I 47.0 100.4 474.0 8.46e-163
ADB92576.1 Ccb2 BGC0001225.5 NRPS:Type I 48.0 100.4 472.0 7.15e-162
KGA48878.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002413.3 NRPS:Type I 47.0 99.4 468.0 1.43e-160
MBX9445642.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002414.3 NRPS:Type I 47.0 100.0 463.0 1.74e-158
AAO56101.1 yersiniabactin_synthetase,_salicylate_ligase_component BGC0002570.2 NRPS:Type I+PKS 48.0 94.4 458.0 5.84e-157
ACR11042.1 Enterobactin_synthetase_component_E/2,3-dihydroxybenzoate-AMP_ligase BGC0000451.5 NRPS:Type I 47.0 98.0 458.0 9.87e-157
AAK95837.1 putative_2,3-dihydroxybenzoate-AMP-ligase_PhbE BGC0002495.2 NRPS:Type I 45.0 98.3 455.0 3.01e-155
CCP45172.1 Bifunctional_enzyme_MbtA:_salicyl-AMP_ligase_(SAL-AMP_ligase)_+_salicyl-S-ArCP_synthetase BGC0001021.5 NRPS:Type I+PKS 44.0 99.3 455.0 3.81e-155
AAM77987.1 adenylate_ligase BGC0000112.5 PKS:Iterative type I 45.0 100.4 454.0 8.62e-155
CAA73130.1 Irp5_protein BGC0000467.5 NRPS:Type I 48.0 93.7 451.0 3.35e-154
ABY66018.1 CoA_ligase BGC0001008.5 PKS:Iterative type I 46.0 100.2 452.0 3.54e-154
CAJ87594.1 2,3-dihydroxybenzoate-AMP_ligase BGC0001055.5 NRPS:Type I+PKS 48.0 93.7 448.0 5.4e-153
ABL70475.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002493.3 NRPS:Type I 45.0 100.4 435.0 1.17e-147
AFV52187.1 acyl-CoA_synthetase BGC0000081.5 NRPS:Type I+PKS:Iterative type I 45.0 99.6 431.0 5.53e-146
EET76301.1 putative_(2,3-dihydroxybenzoyl)adenylate_synthase BGC0002685.2 NRPS:Type I 44.0 102.0 430.0 3.44e-145
ATV95617.1 CoA_ligase BGC0001503.4 PKS 44.0 101.3 429.0 4.42e-145
ACN64830.1 PokM3 BGC0001061.4 PKS:Type II aromatic 43.0 100.6 428.0 1.21e-144
CAG69514.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000352.5 NRPS:Type I 43.0 101.9 421.0 3e-142
BAC87906.1 probable_acinetobactin_biosynthesis_protein BGC0000294.5 NRPS:Type I 44.0 98.0 415.0 8.45e-140
AAO07763.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000460.5 NRPS:Type I 41.0 97.2 404.0 1.37e-135
AKQ52536.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002533.2 NRPS:Type I+PKS 41.0 97.0 400.0 4.53e-134
CCC55917.1 putative_acyl_CoA_ligase BGC0000973.5 NRPS:Type I+PKS:Type I 43.0 98.9 400.0 1.62e-133
AEM06018.2 hypothetical_protein BGC0000966.5 NRPS:Type I+PKS 42.0 98.1 398.0 3.28e-133
AFD30957.1 CrmE BGC0000966.5 NRPS:Type I+PKS 42.0 98.1 398.0 8.92e-132
MBN3579117.1 AMP-binding_protein BGC0002613.2 NRPS:Type I+PKS 41.0 95.9 394.0 1.78e-131
CAP20363.1 equibactin_siderophore_biosynthetic_protein BGC0000347.5 NRPS:Type I 38.0 94.6 381.0 8.89e-127
ADQ74621.1 salicylyl-AMP_ligase BGC0000921.5 other:shikimate-derived+PKS+NRPS:Type I 39.0 95.5 367.0 2.04e-121
KZM73517.1 hypothetical_protein BGC0000632.5 terpene+saccharide 40.0 97.4 326.0 3.75e-105
AHH25585.1 AMP-dependent_synthetase_and_ligase BGC0000957.5 NRPS:Type I+PKS 30.0 99.4 217.0 6.36e-61
BBD17745.1 AMP-ligase BGC0001918.3 NRPS:Type I+PKS 31.0 94.4 196.0 5.9e-56
AWX24488.1 acyl-CoA_ligase BGC0001695.5 NRPS:Type I 32.0 94.6 187.0 6.3e-53
MBE3200457.1 AMP-binding_protein BGC0002409.3 NRPS:Type I 30.0 97.0 182.0 1.08e-50
WP_010639243.1 AMP-binding_protein BGC0000958.5 NRPS:Type I+PKS:Type I 29.0 94.1 177.0 2.92e-49
AQT01384.1 SgnS0 BGC0001690.5 PKS 29.0 99.3 175.0 2.33e-46
AGY30675.1 Ann3 BGC0001298.4 PKS:Type I 30.0 92.8 168.0 1.39e-45
AAF81723.1 putative_acyl-CoA_ligase_EncH BGC0000220.4 PKS:Type II 28.0 96.1 168.0 1.98e-45
QIC03945.1 EncH BGC0002366.2 PKS 28.0 96.1 167.0 3.76e-45
CAC20930.1 PimS0_protein BGC0000125.5 PKS 29.0 99.3 169.0 2.77e-44
AHD25943.1 putative_acyl-CoA_ligase/oxygenase_fusion_protein BGC0000208.5 PKS 27.0 98.9 156.0 9.52e-41
CAO85890.1 aryl-coA_ligase BGC0000110.5 PKS:Type I 30.0 99.1 150.0 7.65e-39
ONK09689.1 Beta-ketoacyl-acyl-carrier-protein_synthase_I BGC0001647.3 PKS 29.0 96.1 152.0 1.01e-38
ABU70356.1 hypothetical_protein BGC0001890.3 NRPS:Type I 25.0 100.7 144.0 4.69e-37
QQZ01622.1 amide_synthase BGC0002497.3 other:other 28.0 93.7 136.0 2.39e-34
QVQ68786.1 mmyL BGC0002129.4 PKS 27.0 95.9 131.0 1.75e-32
WP_240809958.1 long-chain_fatty_acid--CoA_ligase BGC0002686.2 NRPS:Type I 27.0 101.1 130.0 3.21e-32
QTC09983.1 benzoate-CoA_ligase BGC0002372.3 PKS+terpene+other:other 26.0 96.8 129.0 1.1e-31
AZY91996.1 hypothetical_protein BGC0002022.4 PKS 27.0 100.9 129.0 1.32e-31
NP_626687.1 acyl-CoA_synthetase BGC0000595.3 ribosomal:unmodified 29.0 92.9 127.0 2.04e-31
QYA95681.1 amino_acid_adenylation_domain-containing_protein BGC0002676.2 NRPS:Type I 28.0 100.0 125.0 8.32e-30
BCK51658.1 putative_acyl-CoA_synthetase BGC0002520.2 PKS 28.0 92.8 122.0 1.23e-29
MBD2892711.1 3-methylmercaptopropionyl-CoA_ligase BGC0002718.2 NRPS:Type I 25.0 100.4 121.0 4.56e-29
AAY37647.1 Amino_acid_adenylation BGC0000437.5 NRPS:Type I 25.0 101.7 122.0 8.77e-29
BAQ25518.1 acyl-CoA_synthetase BGC0001288.5 PKS 31.0 65.8 119.0 1.75e-28
AGM05527.1 AMP-dependent_synthetase_and_ligase BGC0002098.2 PKS 28.0 93.7 119.0 2.23e-28
SSTG_01180 BGC0000597.4 ribosomal:RiPP:Proteusin 31.0 69.5 117.0 4.7e-28
AEG64689.1 LpmA BGC0000379.5 NRPS:Type I 24.0 96.7 119.0 5.27e-28
QYA95659.1 amino_acid_adenylation_domain-containing_protein BGC0002676.2 NRPS:Type I 28.0 97.8 119.0 6.05e-28
BBG06561.1 AMP_binding_enzyme BGC0001925.4 other:other 28.0 77.9 115.0 4.17e-27
QOE83925.1 linear_gramicidin_synthase_subunit_B BGC0002051.2 NRPS:Type I 27.0 95.2 116.0 4.42e-27
BCB17035.1 acyl-CoA_ligase BGC0002523.2 NRPS:Type I 26.0 92.0 112.0 2.49e-26
MCC5036796.1 AMP-binding_protein BGC0002638.3 NRPS:Type I 29.0 69.1 110.0 9.3e-26
AEZ51516.1 PmxA BGC0001153.5 NRPS:Type I 25.0 97.0 110.0 1.08e-24
AFK57213.1 DidB BGC0000985.5 NRPS:Type I+PKS 29.0 98.7 109.0 1.62e-24
AJM89735.1 PmxA BGC0001192.5 NRPS:Type I 25.0 97.4 107.0 7.89e-24
AAC06346.1 bacitracin_synthetase_1 BGC0000310.5 NRPS:Type I 24.0 98.1 107.0 7.93e-24
CAM59601.1 non-ribosomal_peptide_synthetase/polyketide_synthase_hybrid_enzyme BGC0000297.5 NRPS:Type I+PKS+saccharide:hybrid/tailoring 25.0 105.2 105.0 1.95e-23
BCN28621.1 non-ribosomal_peptide_synthetase BGC0002441.2 PKS+NRPS:Type I 26.0 96.1 105.0 2.09e-23
QXJ26485.1 amino_acid_adenylation_domain-containing_protein BGC0002370.2 NRPS:Type I 23.0 100.0 103.0 8.91e-23
ACM68682.1 AerA BGC0000298.5 NRPS:Type I 24.0 104.8 102.0 2.51e-22
WP_141576286.1 non-ribosomal_peptide_synthetase BGC0002686.2 NRPS:Type I 26.0 93.3 101.0 4.01e-22
BAP05596.1 CalH BGC0000967.5 NRPS:Type I+PKS:Trans-AT type I 24.0 103.7 102.0 4.16e-22
AAK81827.1 peptide_synthetase BGC0000326.5 NRPS:Type I 27.0 89.0 101.0 6.57e-22
EPS34234.1 hypothetical_protein BGC0002067.3 NRPS:Type I+PKS:Iterative type I 24.0 99.4 100.0 1.26e-21
CAD89774.1 MelC_protein BGC0001010.5 NRPS:Type I+PKS:Type I 26.0 96.1 100.0 1.77e-21
QCQ67875.1 hybrid_peptide_synthetase/polyketide_synthase BGC0002297.2 NRPS:Type I+PKS 24.0 95.0 100.0 2.19e-21
APO47826.1 hypothetical_protein BGC0002653.2 NRPS:Type I 24.0 96.5 99.0 3.98e-21
QOV09194.1 ClyF/NocQ BGC0002597.2 NRPS:Type I+PKS 26.0 107.2 98.0 6.37e-21
BCK51655.1 Adenylate-forming_enzyme BGC0002520.2 PKS 27.0 66.0 96.0 6.74e-21
AKA54626.1 NRPS BGC0001216.5 NRPS:Type I+PKS 28.0 100.7 98.0 8.75e-21
AQX77695.1 NocQ BGC0001704.3 other:other 25.0 105.9 97.0 1.12e-20
KFL51885.1 amino_acid_adenylation_protein BGC0001711.4 NRPS:Type I+PKS 25.0 96.1 96.0 2.24e-20
AMY15066.1 acyl-CoA_synthetase/ligase BGC0001339.5 PKS:Iterative type I 28.0 66.2 95.0 3.27e-20
WP_010639240.1 non-ribosomal_peptide_synthetase BGC0000958.5 NRPS:Type I+PKS:Type I 27.0 100.7 94.0 1.45e-19
AGZ15476.1 putative_non_ribosomal_peptide_synthetase BGC0001036.5 NRPS:Type I+PKS 26.0 99.3 93.0 2.6e-19
CAG23957.2 NRPS/PKS_protein BGC0001089.5 NRPS:Type I+PKS:Type I 23.0 101.7 91.0 1.44e-18
AKL71650.1 NocQ BGC0001703.3 other:other 25.0 103.2 90.0 2.31e-18
DAC76734.1 type_I_polyketide_synthase/non-ribosomal_peptide_synthetase BGC0001885.3 NRPS:Type I+PKS 25.0 97.6 90.0 2.6e-18
NHN68325.1 amino_acid_adenylation_domain-containing_protein BGC0002719.2 NRPS:Type I 25.0 97.6 89.0 4.46e-18
MBC5793737.1 non-ribosomal_peptide_synthetase_(depsipeptide_synthetase) BGC0002480.2 PKS+NRPS:Type I 24.0 109.1 88.0 9.35e-18
BBC83957.1 nonribosomal_peptide_synthetase BGC0001636.4 NRPS:Type I 27.0 71.0 88.0 1.41e-17
EJP62835.1 nonribosomal_peptide_synthase,_putative BGC0002203.2 NRPS:Type I+PKS+other:other 23.0 87.0 87.0 1.78e-17
PLB46276.1 acetyl-CoA_synthetase-like_protein BGC0001712.3 other:other 24.0 101.1 87.0 2.18e-17
BAW32323.1 hybrid_cis-AT_polyketide_synthase_-_nonribosomal_peptide_synthetase BGC0001630.4 NRPS:Type I+PKS 25.0 97.8 87.0 3.03e-17
AKJ15896.1 non_ribosomal_peptide_synthetase BGC0002735.2 PKS+NRPS:Type I 26.0 97.8 84.0 1.22e-16
BAB69699.1 iturin_A_synthetase_B BGC0001098.5 NRPS:Type I+PKS 22.0 95.5 85.0 1.25e-16
simA BGC0000334.4 NRPS:Type I 25.0 100.6 84.0 1.72e-16
BAP82667.1 non-ribosomal_peptide_synthetase_A-domain_containing_protein BGC0001148.5 NRPS:Type I+ribosomal:RiPP 27.0 98.5 81.0 1.48e-15
BAP05589.1 CalA BGC0000967.5 NRPS:Type I+PKS:Trans-AT type I 21.0 96.3 80.0 3.41e-15
CBF80711.1 TdiA_[Source:UniProtKB/TrEMBL;Acc:A7XRY0] BGC0000442.5 NRPS:Type I 25.0 73.2 77.0 1.77e-14
AAQ59161.2 enterobactin_synthetase_component_F BGC0002679.2 NRPS:Type I 28.0 67.3 76.0 7.48e-14
PVC99845.1 amino_acid_adenylation_domain-containing_protein BGC0002100.2 NRPS:Type I+other:other 25.0 96.7 74.0 1.05e-13
ATQ39428.1 cyclosporin_C_synthetase BGC0001565.4 NRPS:Type I 24.0 97.6 75.0 1.74e-13
AEC14349.1 nonribosomal_peptide_synthetase BGC0000377.4 NRPS:Type I 23.0 95.7 72.0 6.58e-13
CAE17538.1 acyl_CoA_ligase BGC0000210.5 PKS:Type II+saccharide:oligosaccharide 25.0 75.7 67.0 2.18e-11
WP_012015338.1 AMP-binding_protein BGC0001458.4 other:aminocoumarin 23.0 90.7 63.0 3.83e-10