LOCUS       NZ_CAKMXI010000016      5803 bp    DNA     linear   CON 03-JUN-2024
DEFINITION  Streptomyces atroolivaceus strain TUE2108, whole genome shotgun
            sequence.
ACCESSION   NZ_CAKMXI010000016
VERSION     NZ_CAKMXI010000016.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces atroolivaceus
  ORGANISM  Streptomyces atroolivaceus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 192723)
  AUTHORS   Wibberg,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-FEB-2022) CEBITEC, Genome Research of Industrial
            Microorganisms (GRIM), Universitaetsstrasse 27, 33615, NRW, Germany
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_928722305.1-RS_2024_06_03
            Annotation Date                   :: 06/03/2024 04:23:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,057
            CDSs (total)                      :: 6,983
            Genes (coding)                    :: 6,683
            CDSs (with protein)               :: 6,683
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 2 (5S, 16S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 300
            CDSs (without protein)            :: 300
            Pseudo Genes (ambiguous residues) :: 0 of 300
            Pseudo Genes (frameshifted)       :: 123 of 300
            Pseudo Genes (incomplete)         :: 254 of 300
            Pseudo Genes (internal stop)      :: 20 of 300
            Pseudo Genes (multiple problems)  :: 87 of 300
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:59:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 186920
            Orig. end                         :: 192723
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CAKMXI010000016.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..5803
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ectoine"
                     /region_number="4"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..5803
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..5803
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:5399](-)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5399)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     misc_feature    complement(106..119)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.73"
                     /tool="antismash"
     gene            216..713
                     /locus_tag="NBY68_RS31280"
     CDS             216..713
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471158.1"
                     /locus_tag="NBY68_RS31280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_250293836.1"
                     /transl_table=11
                     /translation="MGLNPEPDHRSRDAAREGSEFVELLEVLWEHGREAVPTGPVSPSQ
                     LRVLYTLDREDGINLRMLADALGSASPSVSRLCDRLQATGFVERTPSPVSRRELELRLT
                     SHGKAYLVDLRMRREKVLMSTIDAMPPKARRSLLEGLRAFRNAASAGGQDSSGARPLRS
                     TA"
     gene            complement(742..1929)
                     /locus_tag="NBY68_RS31285"
     CDS             complement(742..1929)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048445.1"
                     /locus_tag="NBY68_RS31285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_250293816.1"
                     /transl_table=11
                     /translation="MDRFAAVERELRRAAPHLLLDVVTAALREQYDVQNVELRLADYGM
                     STLQVVSEAPLAEPVPVHNSPQGRAFGAQEPYVEHRATPGPATVHLPVTVRGDRLGVLS
                     VTAPESGCSPAALAGMQQICEALGHEILVAGRDTDLYLLARRATRLTLAAEMQWQLLPG
                     RSVSRPEFSLGAHLEPAYAIFGDNFDWSVSAHHLTLTVTNGMGKGMEAALLTNLVVNAL
                     RNARRAGLDLPGQASLADQAVYAQHRGALHASVLLLRFDLATGEVEAVDAGSPRMWRLR
                     GRSVEPLEFDAQLPLGMFEETEYVAERLRVEPGDRLLIGSDGVYDSASAAGERYGQRAL
                     ALSLSAHRFLPSEQVPQAVLRDLRDYRGATPLDDDALVVCLDWFGRQASTGDTSA"
     gene            2220..3077
                     /locus_tag="NBY68_RS31290"
     CDS             2220..3077
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158118.1"
                     /locus_tag="NBY68_RS31290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="WP_250293837.1"
                     /transl_table=11
                     /translation="MRTDGAPVSETAAERMGELPWIEDAGKVSPKDARALSTLFFEQLQ
                     VLEEGTHEYQYARNTLIEMNISLVRFAARRFRNRGSGDMEDITQVGTIGLIKAIDRFEL
                     SREVEFATFAVPYIVGEIKRFFRDTTWAVHVPRRLQELRVELARAKDELATRLDRDPTV
                     KELADHLNLTEDEVIEGVIASNGYTAGSLDLPTDAGETTGTASRTFADILGEPDSAMET
                     VENLHALAPLLQELDDRERRIIEMRFGQEMTQSQIGAELDVSQMHVSRLLTRTLGKLRA
                     GMLA"
     gene            3173..3529
                     /locus_tag="NBY68_RS31295"
     CDS             3173..3529
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="NBY68_RS31295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_250293817.1"
                     /transl_table=11
                     /translation="MTAPAILRRAQDRRPPPAADRAERAQLAGVRVDPLIEFERVEAAL
                     ELVAAGAGDTIAGRAVIASPSFPAGLHTTPFSERLYDTVPLVRRHGHPLSRATRELARL
                     AENTIRELGHGLMT"
     gene            complement(3811..>4242)
                     /locus_tag="NBY68_RS31300"
     CDS             complement(3811..>4242)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156966.1"
                     /locus_tag="NBY68_RS31300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_250293818.1"
                     /sec_met_domain="PhyH (E-value: 9e-17, bitscore: 55.3,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="HMRTVSVSIALTENFDTNGGLMIMPGSHKSFVGCAGETPKDNYKK
                     SLQMQDAGIPSDEVLTKMADRHGIKLFTGKAGSATWFDCNAMHGSGDNITPYARSNVFI
                     VFNSVENTAQEPFAAPIRRPEFIGARDFTPVGSGSEGGS"
     assembly_gap    4243..4791
                     /estimated_length=549
                     /gap_type="unknown"
                     /linkage_evidence="unspecified"
     gene            complement(<4792..4997)
                     /locus_tag="NBY68_RS31305"
                     /pseudo=""
     CDS             complement(<4792..4997)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156966.1"
                     /locus_tag="NBY68_RS31305"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ectoine hydroxylase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MITDVRADLYPSRGAAEMTTPRQDPVIWSAPGTPGPVAAKDLQGF
                     EENGFLTVDQLIRPEEVAVYRAE"
     gene            complement(5001..5399)
                     /locus_tag="NBY68_RS31310"
     CDS             complement(5001..5399)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123624.1"
                     /locus_tag="NBY68_RS31310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ectoine synthase"
                     /protein_id="WP_250293819.1"
                     /sec_met_domain="ectoine_synt (E-value: 4.8e-55, bitscore:
                     178.2, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRSFSDIENTDRHVRSASGTWESKRIVLAKEKVGFSLHETVLY
                     AGTETSMWYANHIEAVLCTEGEAELTNDESGETHWISPGTMYLLDGHERHTLRPKTDFR
                     CVCVFNPPVTGREDHDENGVYPLLTEEG"
     CDS             complement(5542..>5801)
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=2
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156968.1"
                     /locus_tag="NBY68_RS31315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_250293820.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.3e-13, bitscore:
                     43.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="QALLAIAEEHQETEARIRGRGLVWGMQFPEAPRASAVCMRAFELG
                     LLLETSGPESEVVKVLPPLTISSEELEEGLRILARAVRETG"
     gene            complement(5542..>5803)
                     /locus_tag="NBY68_RS31315"
ORIGIN
        1 ccgcatgaca actgttgtca tgcggcaacc tatgggtggg ccggtggcga cctcggaagc
       61 ccgtggtgcg cgggggtacg atatccgggg ccacgcgcgt gtcccggaac ctttgtcctg
      121 gctttccata cgagcgcatc agacgcccgg ctcgcttgct cggtccggtg gccagacgga
      181 cgagtgaggc gatgccggat cggagtgtca tcaccatggg cctgaacccc gaacccgacc
      241 accggtcccg ggatgcggcc cgtgagggtt ccgagttcgt cgaactcctc gaagtcctct
      301 gggagcacgg acgtgaggcc gttccgacag gcccggtctc cccttcccag ctgcgcgtgc
      361 tgtacacgct ggacagggag gacggcatca acctgcggat gctcgccgac gccctcggtt
      421 cggcctcccc ctcggtcagc aggctgtgcg accgactgca ggccacgggg ttcgtcgagc
      481 gcacgcccag cccggtgagc cgccgggaac tggaactccg gctgaccagc cacggcaagg
      541 cgtacctcgt cgacctgcgt atgcgcaggg agaaggtgct gatgtccacg atcgacgcga
      601 tgccgcccaa ggcacggcgt tcgctcctcg aagggctcag ggccttccgc aacgcggcct
      661 cggccggggg gcaggacagc agcggggcga gacccttgcg gtcgaccgca tgacgaccgg
      721 tcgaccgcaa gtcgttccag ttcacgcgga tgtgtcaccg gtggaggcct gccggccgaa
      781 ccagtccagg cagaccacca gggcgtcgtc gtccagtggc gttgcacctc ggtagtcccg
      841 caggtcccgg aggaccgctt gcggcacctg ctcggacggc aggaagcggt gcgcggacag
      901 cgacagcgcg agggcgcgct gcccgtagcg ctccccggcc gccgacgcgc tgtcgtagac
      961 accgtcgctc ccgatcagaa gccggtcgcc aggttccacg cgcaggcgct ccgcgacgta
     1021 ctccgtctcc tcgaacatgc ccagcgggag ctgcgcgtcg aattcgagcg gttcgacgct
     1081 gcgccccctc agccgccaca tccgggggga ccccgcgtcc accgcctcca cctcgcccgt
     1141 ggccaggtcg aagcgcagca gcaggaccga agcgtgcagc gcgccacggt gctgggcgta
     1201 gacggcctga tcggcgaggc tggcctggcc ggggaggtcg aggccggcac gccgggcgtt
     1261 gcgcagcgcg ttgacgacga gattggtcag cagggccgcc tccatcccct tccccatgcc
     1321 gttggtgacg gtgagggtga ggtgatgggc cgacaccgac cagtcgaagt tgtcgccgaa
     1381 gatcgcgtaa gcgggctcca ggtgggcgcc caacgagaat tcggggcggg acacggagcg
     1441 gcccggcagc aactgccact gcatctccgc ggccagggtg agccgtgtgg cgcggcgcgc
     1501 gaggaggtag agatcggtgt cccgtccggc gaccaggatc tcgtggccga gcgcttcgca
     1561 gatctgctgc atccctgcca gggccgccgg cgagcagccg ctctccggcg ccgtgacgga
     1621 gaggacaccg agccggtcgc cccggacggt caccggcagg tgcacggtgg ccgggcccgg
     1681 cgtcgcccgg tgctccacat acggctcctg ggccccgaag gcccggccct gcgggctgtt
     1741 gtgcacgggc accggctcgg cgagcggcgc ctcggagacc acttggagcg tgctcatgcc
     1801 gtagtcggcg agccgcagct ccacgttctg cacgtcgtac tgctcccgca gagccgccgt
     1861 gacgacatcg aggagcagat gaggtgcggc tctgcgcagc tcccgctcga cggcagcgaa
     1921 tctgtccacg tgatcctgtt tctcgtcgtg ccgcgccgaa accgggaccg tccgtgggcc
     1981 ccggccgtcg gcctccagcg tacggagcct gtaaccagat cctgcggcaa tcccgcaagg
     2041 gcgcgccggt ttccggtacc gctcatccta cgatgtccgg agacaactgt ttccgcacag
     2101 caagaaatat cgcgtccgca cgcatggccc tcccgagccg gggcaggggc tggcacagga
     2161 agcgcgctcg gcacgaggga gggtggaacg aaatgatgac tgaagagacc cccggaacca
     2221 tgcggactga cggtgcgccg gtttcggaga ccgcagcgga gcgcatgggc gagctgccgt
     2281 ggatcgaaga cgcgggcaag gtgagcccga aggacgcccg tgcgctgtcg acgctgttct
     2341 tcgagcagct gcaggtcctg gaggagggca cgcacgagta ccagtacgcg cgcaacacgc
     2401 tcatcgagat gaacatctcc ctcgtccggt tcgcggcacg ccgcttccgc aaccggggca
     2461 gcggtgacat ggaggacatc acccaggtcg ggaccatcgg cctcatcaag gccatcgacc
     2521 ggttcgagct ctcccgtgag gtcgagttcg ccaccttcgc cgtcccctac atcgtgggcg
     2581 agatcaagcg cttcttccgt gacacgacct gggccgtcca cgtcccgcgt cggctgcagg
     2641 aactccgcgt ggaactcgcc agggcgaagg acgagctcgc cacccgcctc gaccgcgacc
     2701 ccacggtgaa ggaactggcc gaccacctga acctcaccga ggacgaggtc atcgagggtg
     2761 tcatcgcgtc gaacggctac accgccggat ccctggacct tccgaccgac gccggcgaga
     2821 cgacgggcac ggcttcgcgc accttcgccg acatcctggg cgagccggat tcggccatgg
     2881 agacggtgga gaacctgcac gcactggccc ctcttctgca ggaactcgac gaccgcgagc
     2941 gccgcatcat cgagatgcgc ttcggccagg agatgacgca gtcccagatc ggtgccgaac
     3001 tcgacgtctc ccagatgcac gtctcccgtc tcctcacgcg caccctcggc aagctccgcg
     3061 ccggcatgct ggcctgattc cgtacgtccg tcgagatgcg gccggcggtc cgcccgtcgg
     3121 ccgcatctca gcgcccgtat ccgcacggac cgggcattcc ggcgtccgtg gggtgacggc
     3181 cccggcaatc ctccgacgag cgcaggacag gcgcccgccc ccggcggcag atcgcgccga
     3241 gcgcgcccag ctagccggag tccgcgtcga tcccctgatc gagttcgaac gcgtggaggc
     3301 ggcactggag ctggtggcgg caggagcggg cgacacgatc gccggccggg ccgtgatcgc
     3361 cagcccgtca ttccccgcag gactgcacac cacccccttc tccgaacgcc tgtacgacac
     3421 cgtcccgctg gtcaggcgtc acggtcatcc cctctcgcgc gccacccggg aactcgcccg
     3481 tctcgccgag aacaccatcc gcgagctcgg ccacggcctg atgacctgac gcgccgggca
     3541 ggtgcggagc ggggtccgac ctcccacagg gaaaccctgt gggaggcaca ggaactaccc
     3601 ctcaagccct gtgtcggcgt cgcgtctacc gtccggggta tcgggtcgga tgcgcccttc
     3661 cctcacccgc gccgttcgcg tcccctggcg ggcgagggcg atcagacccg gccgaggtca
     3721 cgatccgcgg tccctgggtg cgtgagaaga gaacacacgc cagggagagg agcggcatgg
     3781 gcgctcatgc gccagccacg cgccggcctg tcaactacct ccttcacttc cggaccctac
     3841 gggcgtgaag tcgcgggctc cgatgaactc gggccggcgg atcggggcgg cgaagggttc
     3901 ctgcgctgtg ttctccacgc tgttgaagac gatgaagacg ttgctgcggg cgtacggggt
     3961 gatgttgtcc ccggagccgt gcatggcgtt gcagtcgaac caggtcgccg agccggcctt
     4021 gccggtgaag agcttgatgc cgtgccggtc ggccatcttc gtcagcacct cgtcggacgg
     4081 gatgccggcg tcctgcatct gcagggactt cttgtagttg tccttcggcg tctcgcccgc
     4141 acagccgacg aacgacttgt gcgaaccggg catgatcatc agcccgccgt tggtgtcgaa
     4201 gttctcggtg agcgcgatcg agacggacac ggtccgcatg tgnnnnnnnn nnnnnnnnnn
     4261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nagttccgcc
     4801 cggtagacgg ccacctcctc gggcctgatg agctggtcga cggtgaggaa accgttctcc
     4861 tcgaagcctt gcaggtcctt cgcggctacc ggcccgggcg tccccggcgc ggaccagatg
     4921 accgggtcct ggcggggagt ggtcatctcg gcggcgccgc gcgaggggta caggtcggcg
     4981 cgtacatcgg tgatcatggt tcagccctcc tctgtcagca gcgggtatac accgttctcg
     5041 tcatggtcct cccgaccggt gacgggggga ttgaagacgc acacgcagcg gaagtcggtc
     5101 ttgggccgga gcgtgtggcg ctcgtgcccg tccagcaggt acatcgtgcc gggggagatc
     5161 cagtgcgtct cgccgctctc gtcgttcgtg agctcggcct cgccctcggt gcacaggacg
     5221 gcctcgatgt ggttcgcgta ccacatcgac gtctccgtgc ccgcgtacag cacggtctcg
     5281 tggagcgaga agcccacctt ctccttggcg agcacgatgc gcttgctctc ccaggttcct
     5341 gaagcggacc tgacgtgccg gtcggtgttc tcgatgtcac tgaaagatcg gacgatcacg
     5401 gtggggtggc acccttccta cgttggcacg gcccacggtc ggaatgcggc gtgagcggtg
     5461 acggggcgtt gagctgtgat ggggcgcgag cggccggccg gccttcccgg ctctcgggcg
     5521 gacgcttcgc gtccaggtgg ttcagccggt ttcccgcaca gctctcgcaa ggatccgcag
     5581 gccctcttcg agctcctccg aggagatggt gaggggcggc agtaccttga ccacctcact
     5641 ctcaggccct gacgtctcca gcagcaggcc cagctcgaat gcgcgcatgc agacggcgga
     5701 ggcacggggt gcctcgggga actgcatgcc ccagaccagg ccgcggccac ggatccgggc
     5761 ctcggtctcc tggtgctcct ccgcgatcgc cagcagtgcc tgt
//
