LOCUS       NZ_CAKMXI010000004     21074 bp    DNA     linear   CON 03-JUN-2024
DEFINITION  Streptomyces atroolivaceus strain TUE2108, whole genome shotgun
            sequence.
ACCESSION   NZ_CAKMXI010000004
VERSION     NZ_CAKMXI010000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces atroolivaceus
  ORGANISM  Streptomyces atroolivaceus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 637656)
  AUTHORS   Wibberg,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-FEB-2022) CEBITEC, Genome Research of Industrial
            Microorganisms (GRIM), Universitaetsstrasse 27, 33615, NRW, Germany
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_928722305.1-RS_2024_06_03
            Annotation Date                   :: 06/03/2024 04:23:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,057
            CDSs (total)                      :: 6,983
            Genes (coding)                    :: 6,683
            CDSs (with protein)               :: 6,683
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 2 (5S, 16S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 300
            CDSs (without protein)            :: 300
            Pseudo Genes (ambiguous residues) :: 0 of 300
            Pseudo Genes (frameshifted)       :: 123 of 300
            Pseudo Genes (incomplete)         :: 254 of 300
            Pseudo Genes (internal stop)      :: 20 of 300
            Pseudo Genes (multiple problems)  :: 87 of 300
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:59:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 609762
            Orig. end                         :: 630836
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CAKMXI010000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:11074](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11074)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(100..333)
                     /locus_tag="NBY68_RS13515"
     CDS             complement(100..333)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018551844.1"
                     /locus_tag="NBY68_RS13515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_033304167.1"
                     /transl_table=11
                     /translation="MGTQQEKDELYALDISDVQWLSAPGTENVEERVEIAHLPGGAVAM
                     RSSLDPETVLRYTEAEWRAFVLGARDGEFDLE"
     gene            complement(418..1128)
                     /locus_tag="NBY68_RS13520"
     CDS             complement(418..1128)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153732.1"
                     /locus_tag="NBY68_RS13520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_033304169.1"
                     /transl_table=11
                     /translation="MTKHIAPRRGLLGPRHAGHTLAADHLGALSLPVGDDGVIIGDDAE
                     GRPQLIGFHRPAPYDVLLIGGLWTAQVLALRAAGTGARVAVETGRTQAWTTLAQAAGAG
                     LECVSLHDVGRVPPTGATVGSPVVVVRDCGMRPPRGRVVSSPWQSVLTLLPYLSPVAPR
                     LMRAATLVGVQRVSPAESEQIGRILGLARTESEALPTLADGVTLWVSGRERHWVMTSAT
                     DVEAGLLGTARRMD"
     gene            complement(1125..2465)
                     /gene="eccE"
                     /locus_tag="NBY68_RS13525"
     CDS             complement(1125..2465)
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="eccE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965865.1"
                     /locus_tag="NBY68_RS13525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type VII secretion protein EccE"
                     /protein_id="WP_250289037.1"
                     /transl_table=11
                     /translation="MGAATGERARRSTHRTPRPSRRQRSNGSDGTAPHRSADAPAATTL
                     HSISRTGRVGPALRQMVLVEAALAVAVVGAALGGAWLIPAGVIACLLILLAVVRRRGRA
                     VQDWLSTVSSLRRRNRSAVAAPVETEPQLAPVAESVPGFAPYIYVDGARRTVGMVGDGT
                     FLTAVVRVEASGESLRQAQGARALPLSLLGDALAVDDIVLESAQLVQQVRPAPAPHLPE
                     RSVARLSYAPLQDRTGAPALRMTWVAVKLDPELCREAVDARGGGLGGAQRCLVRVADHV
                     ASRITGAGFRASVLDQEELNSAVATSACANPILSARAGRPDAAPQRRTAETPRVWRCDD
                     RWHTTYAVDRWPELGRGATPLPRLVSLLTSVPAYATTFSLTVRRGAHQGHVSVRGHVRI
                     TGGSDTELVGVRRTLEQAARHAEVGLVRLDREQLPGVLATLPLGGAQ"
     misc_feature    2492..2507
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    2493..2508
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.55"
                     /tool="antismash"
     misc_feature    2497..2506
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.9"
                     /tool="antismash"
     gene            2649..4181
                     /gene="eccB"
                     /locus_tag="NBY68_RS13530"
     CDS             2649..4181
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="eccB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378783.1"
                     /locus_tag="NBY68_RS13530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type VII secretion protein EccB"
                     /protein_id="WP_033304172.1"
                     /transl_table=11
                     /translation="MASRRDELNAYTFAKRRLVAQFLQPHPSGSEEGAPRPLRAVVPGV
                     IVGVVVLAVFGAWGMFKPVAPQKWDTPYENVIIASKSTTRYVVLTTDGKTQLHPVLNMS
                     SAKLLLAPDKGKVVNVDESVLDSGKIPHGATLGIPYAPDRLPDKGEAGSTKRWAVCERP
                     GEGGRAIQKAAFVFAEREQKKTEGANKLHGGEVMYVEGPGPDRTRYIVDATGKAYPVEN
                     NELLLRTLVDQDRVPQRVSAEWLATLHMGDEVTFPAIEGTPGTDAGVPGELQPDDNKVG
                     MILAATSGTRTQQYVVLKGRVAPVSDFVAKLLLSSRDLVDLEQDGKAKSVSAGAFEPGE
                     AFGQEADWPTNEATPVNSASAADGSRNTVCNVLRGVSEKNGTSTLSTWAGKGFPATLPT
                     GSSSAYVTPGSGQLFRQFKGSSPESGPLFLVTDTGLRYAMQSNGDSAQDDSGIGESGTK
                     EERKQRQQEAQQAQIKLGYKDVDPAPVPADWSAFLPTGPRLSTGAARQPQGS"
     gene            4192..5445
                     /gene="mycP"
                     /locus_tag="NBY68_RS13535"
     CDS             4192..5445
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="mycP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984702.1"
                     /locus_tag="NBY68_RS13535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type VII secretion-associated serine protease
                     mycosin"
                     /protein_id="WP_250289038.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.4e-49, bitscore:
                     162.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQSTSTRSRRLLTAAAATGVLLVTLPMPMAAADDATQCTFPSK
                     KYAGRPWALQRVLMDELWEQSTGKGVRVAVIDTGVDVKNPQLTKAVDTGSGRNYLDKNL
                     KDENGNKIERGNENGTTDLVGHGTKVAGIIAAREAKGTGFTGLAPDATIIPIQQNDAEG
                     HGTAETLAEAIRYAAGEGGADVINISQDTANAVEPAPALKEAVDAALAQDIVIVASAGN
                     DGLGGNVKETYPASFAGVLAVAASDRNNERAAFSQSGDFVGVAAPGVDMVSTVPGGGHC
                     SDNGTSFSAPYVAGVAALIKAKHKDWTQEQIVAQIQQTAERSTAGHDRLVGWGVVDPVR
                     ALTEDDKPIEKPVAHEGVSKGEAPVPAAFHLGETADERNARLATYVVVGGGVLVAAIAG
                     TAVAVRDRHRRQGRPGGS"
     gene            5609..6049
                     /locus_tag="NBY68_RS13540"
     CDS             5609..6049
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015578975.1"
                     /locus_tag="NBY68_RS13540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_033304174.1"
                     /transl_table=11
                     /translation="MAEGKGNLRRGVGALEKFQKSVNALLAELESSPAGKSKVAAQTVS
                     RTALSGQNTCFAEADGLYTQYNRVHESLVTLSKSLSDQIEYLNLGVHAAAVGFDNVDDD
                     TRRRFHEIRTRLDKEHEQAQGEKTVKPEQNADKKSDAGWAAE"
     misc_feature    6931..6944
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.35"
                     /tool="antismash"
     misc_feature    7339..7353
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
     gene            7834..9075
                     /locus_tag="NBY68_RS13550"
     CDS             7834..9075
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153726.1"
                     /locus_tag="NBY68_RS13550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /protein_id="WP_250289040.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 9.9e-45, bitscore:
                     148.1, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQTRRRRMPGLRRRLFGAVAVAAAWSVGFSGTAPSAVAADVQSK
                     QWYLSAMQAAEMWKTATGEGIKIAVIDTGVNSSTPSLEGQVLKGLDATGAEGEETDDYE
                     GHGTTMAELIAGTGKGGGLKGLAPGAKIIPMRVAGAKWQTTETLNPHDTSDAIRAAADS
                     DAKIISMSFGNDFASDREEEAVKYAQSKGKLFFASVGNEAKNGNPERYPAAYAEVVGVS
                     SADREGKVAEYSQNGRTVDIAAPGNDIPYWCDATFKSYCDGDGGTSAATAIASASAALL
                     WSAHPDWTANQVLNVLFDTASRDWEKGTLSKYLGHGLIRPSMNILKGKGTPGAADVSPL
                     TKEKTPGSAGSAAPSASASSQPEKSEKADDAAMAGSSTEKNDGSQLGLILGGVAVVLVL
                     GVGGFLFARRRRTA"
     misc_feature    complement(9096..9112)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 23.01"
                     /tool="antismash"
     gene            9152..9526
                     /locus_tag="NBY68_RS13555"
     CDS             9152..9526
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061854.1"
                     /locus_tag="NBY68_RS13555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="WXG100 family type VII secretion target"
                     /protein_id="WP_033304179.1"
                     /transl_table=11
                     /translation="MADQKLSDDALIKIEGELSTRFESVRGQIKTLQGTIDSLEGAWKG
                     IGATAFNSKQDEINRRMGNIAVRMANFQEAIKAARVISGNTEDEIKAALQGVDVVDGYS
                     AGAEAKTAAITPPPSALNSL"
     gene            9587..9886
                     /locus_tag="NBY68_RS13560"
     CDS             9587..9886
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153724.1"
                     /locus_tag="NBY68_RS13560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="WXG100 family type VII secretion target"
                     /protein_id="WP_250289041.1"
                     /transl_table=11
                     /translation="MPTNDGTMVVTYASLEQAAGDIDRQSRQLQEDLAAIKRVVASASE
                     LWVGEAKTAYDAAQAGWDRDATAIQTALTEISRKVRDAGMAYQGGDKRARANFE"
     gene            complement(10001..11074)
                     /locus_tag="NBY68_RS13565"
     CDS             complement(10001..11074)
                     /EC_number="4.2.3.166"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153723.1"
                     /locus_tag="NBY68_RS13565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="(+)-(1(10)E,4E,6S,7R)-germacradien-6-ol synthase"
                     /protein_id="WP_250289042.1"
                     /sec_met_domain="T1TS (E-value: 7.5e-75, bitscore: 248.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPAPAPKIPQLWVPLPSGIHPGWREIDERSAAWLDRFGLYSDR
                     AQRERLMRISVGEITSRGAPAGRPAALQWTSDFLMWLFAFDDEFCDEGPVAASPDATLL
                     IITKLQRIAEVPWAAPADDSYSAALRELRLRLDHLTTPVQTARWAASFRAYLQGQIWMA
                     SNSAHGRIPSLSDHLAVRLDSSGVKIFSTLSEIIHGYDLPAADYERHDIRGFVEVFASI
                     IGWSNDLISYHKERQRSQDSFGNIVDLIAYERKCSLDEAVSETAMMHTRAMTLYLRLRD
                     QILRDAGSELRRWITDCDSWIRADYDWSLTTNRYVNPEDPADLPAGSAASPFREREADQ
                     PLPIPSVAWWWTLLKDQ"
     gene            complement(11682..15650)
                     /gene="eccCa"
                     /locus_tag="NBY68_RS13570"
     CDS             complement(11682..15650)
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="eccCa"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127993.1"
                     /locus_tag="NBY68_RS13570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type VII secretion protein EccCa"
                     /protein_id="WP_250289043.1"
                     /transl_table=11
                     /translation="MSQIVVKRPPRALPSEVPGEQVQLQPPPELPRGQQEGVMMQLLPM
                     LGMGGSVVFFFMTPNPIMRIMGMIMIASTIAMAIAMIIRFRRGTQGQLADMRRDYLKYL
                     TQTRRAVLRTARQQRDAQFYLHPSPEQLWALVAEGSRLWERRVGDADFAHVRIGLGSQE
                     LATPLVAPDTAPVDELEPLTAGAMQQFLTTHSTLDGLPMAVSLRAFYHLTISGEGESAR
                     ATARAMIGSLASLHSPEDLIIAVATGRDAAPRWDWTKWLPHVQARGSTDGAGSRRLIST
                     SVAELEEMLAGHLDGRPRFQPGGQPLLDQPHVVVVLDGESVPATSALASTEGLQGVTVV
                     EIVTGQVNGARGGLSIVVDPHSLQLESGHGLVYDGLPDLLSHEAAEALARQLAPLHVAT
                     GGDDDEPLLANLEFTDLLNLGDAASVDVSRTWRARSQAERLRVPIGVGEDGAPVMLDLK
                     EAAQEGMGPHGLCVGATGSGKSELLRTLVLGLAVTHTSETLNFVLADFKGGATFAGMAQ
                     MPHVAAVITNLADDLTLVDRMGDSISGELNRRQEMLRDAGNYANIHDYEKARAAGAPLQ
                     PIPSLVLVIDEFSELLTAKPDFIEMFVQIGRIGRSLGVHLLLASQRLEEGRLRGLETYL
                     SYRIGLRTFSAGESRAALGVPDAYHLPNVPGSGYLKYGTDEMVRFKAAYVSGVYRSGAR
                     RAASSGPLPVDRMPVVFTAAPVPVRYVQPAAQTGVPEPRTSEDDALADTVLDVIVRRLE
                     GRGASAHQVWLPPLDNPPSFDELLPGLSAVEGRGLTQPGFEGSGRLVAPLGVVDKPYEQ
                     RRDTLYRDFSGAAGHMQITGGPQSGKSTLLRSLIAGFALTHTPHEVQFYALDFGGGGLA
                     SVSGLPHVGGVASRLDPERVRRTVSEVYGIMARREEYFRSAGIDSIATFRRLRARGDIS
                     VTDQPWGDVFLIIDGWGNFRSDYEGLESAAVDIAQRGLGYGIHLIVTASRSMEVRANLK
                     DHLMNRLELRLGDVMDSELDRKAAVNVPPGVPGRGLTPEKLHFMAAVPRIDGINSDSDL
                     SEATAAMNAEVARHWTAAPAPAVRLLPRELPVHELPAGYAQPERGIAFGIDENNLEPVF
                     LDFERDPFFLVFGESESGKSNLLRLLIKQLTERYDGNAAKFFVIDNRRALLDVTPATHL
                     AEYVPMSNNMDHHADALYDLMKRRTPSPEVTAQELRDRSWWSGPTVYVVVDDYDLVSTS
                     SGNPLAKLTEMLPFSRDVGVRFIIARSTAGAGRALYEPFMQRILELGAQGVMLSGDPVE
                     GDVLGNVRPRPMPPGRGVFVTRRRGNPLVQTGLMDGEA"
     gene            15897..17399
                     /gene="eccD"
                     /locus_tag="NBY68_RS13575"
     CDS             15897..17399
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="eccD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512723.1"
                     /locus_tag="NBY68_RS13575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type VII secretion integral membrane protein
                     EccD"
                     /protein_id="WP_250289074.1"
                     /transl_table=11
                     /translation="MTAQTAATGSGRPGPGVPAGNGTGFCRVTVVAPDSRVDVALPEDI
                     PVADLYPEILRLSGQSPAPGAPVGYHLVRRDGTVLDSGRTLAGLRILDGELLSLRPFSE
                     SLPPAVFDDVSDAVATAVARDRTLWGDSLMRSAGLFGGSVLLVLLGFVLWTSDVRHDMH
                     GLPGILAAVSALLLLALACVRARVYADRGSSIALGTGALANAAVAGAGLLPLGAGQGIG
                     RLQFLLACAAVLVASVILMIAAPEGDGTFVAFVFASVIGALVTFVAIMTGMEPAETAAV
                     CAPLSVGLLAFLPGLSTRFARLPIGFEPPRTTVGDYGTSDPAPQGPVDAERITAQARRG
                     HELLVGLVGGCALVAVGAAAVLGFSDSVWGQLLALATGVAMLMRAHLFRYTAQVGCALG
                     AGLAALVLLGLGLSLNPPVALVKEAFAGETAGLDIRTIWLTAAVAGVAALITAIGLIVP
                     RKGVTPFWGRFLEIAEACVLLTLLPLCLAVFDVYHSIRALTS"
     gene            17576..17866
                     /gene="rpsO"
                     /locus_tag="NBY68_RS13580"
     CDS             17576..17866
                     /GO_component="GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127995.1"
                     /locus_tag="NBY68_RS13580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="30S ribosomal protein S15"
                     /protein_id="WP_003965855.1"
                     /transl_table=11
                     /translation="MPLDAATKKQIMSEFAQKEGDTGSPEVQVAMLSRRISDLTEHLKT
                     HKHDHHSRRGLLILVGQRRRLLQYLAKKDIQRFRALVDRLGIRRGAAGGAK"
     gene            18138..20354
                     /locus_tag="NBY68_RS13585"
     CDS             18138..20354
                     /EC_number="2.7.7.8"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /GO_process="GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512722.1"
                     /locus_tag="NBY68_RS13585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="WP_033304185.1"
                     /transl_table=11
                     /translation="MENETHYAEAVIDNGTFGTRTIRFETGRLAKQAAGSAVAYLDDDT
                     MVLSATTASKRPKDQLDFFPLTVDVEERQYAAGKIPGSFFRREGRPSEDAILTCRLIDR
                     PLRPSFKKGLRNEIQIVETIMALNPDHLYDVVAINAASASTILAGLPFSGPIGATRVAL
                     IKGQWVAFPTHTELEDAVFDMVVAGRVLEDGDVAIMMVEAEATEKTIQLVKDGAEAPTE
                     EVVAAGLEAAKPFIKALCKAQSDLASKAAKPTGEFPVFLDYQDDVLEALSKAVSTELAK
                     ALTIAGKQEREAELDRIKEIAGEKLLPAFEGREKEISGAYRALTKKLVRERVIKDKVRI
                     DGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNMLRMEQQLDTLSPVTRKR
                     YMHNYNFPPYSVGETGRVGSPKRREIGHGALAERAIVPVLPSREEFPYAIRQVSEALGS
                     NGSTSMGSVCASTMSLLNAGVPLKAAVAGIAMGLISEEIDGKTHYVALTDILGAEDAFG
                     DMDFKVAGTKQFVTALQLDTKLDGIPASVLAAALKQARDARLHILDVMNEAIDVPDEMS
                     PNAPRIITVKIPVDKIGEVIGPKGKMINQIQEDTGADITIEDDGTIYIGAQQGSQAEAA
                     RATINAIANPTMPEVGERYLGTVVKTTTFGAFVSLMPGKDGLLHISQIRKLAGGKRVEN
                     VEDVLAVGAKVQVEIAEIDSRGKLSLIPVIEGEEADEKKDDTDK"
ORIGIN
        1 ggaacacgga ggaacgggcc gccgccgcgc accgtgacgc gggcggacac aaggagaggg
       61 cggcagtccc cgacagccgc ccccccaccg tgcggacgcc tactcgaggt cgaattcacc
      121 gtcccgcgcg cccagtacga acgcgcgcca ctcggcctcc gtgtagcgca gtacggtctc
      181 cggatccagc gacgagcgca tggcgaccgc gccccccggg aggtgggcga tctcgacccg
      241 ttcctcgacg ttctcggtac cgggtgcgct cagccactgc acatccgaga tgtcgagagc
      301 gtagagctcg tccttttcct gctgggtgcc catggacccg tcccttcggt cgaactgtgt
      361 cgttcccacg ccatgatcct gaaaagcggc ggatccgggg agcgaacgag acaggattca
      421 gtccatcctg cgagcggtgc ccagcagtcc ggcctctaca tccgtcgcac tggtcatcac
      481 ccagtggcgt tcgcggcccg acacccagag ggtgacaccg tccgcaaggg tgggcagagc
      541 ctcgctctcg gtcctggcga gccccaggat ccggccgatc tgttcggact cggccggaga
      601 cacccgctga acacccacga gcgtcgccgc ccgcatcaac cggggcgcca ccgggctcag
      661 atagggcagc agcgtcagta cggactgcca cggcgaggac accacccggc cgcgaggcgg
      721 gcgcatgccg cagtcgcgca ccacgaccac cggactgccg acggtcgctc cggtcggcgg
      781 aacccggccc acgtcatgga gcgagacgca ctcgagcccc gcgcccgcgg cctgcgccag
      841 cgtggtccac gcctgggtgc ggcccgtctc gaccgccacc cgcgcaccgg taccggccgc
      901 gcgcagcgcc agcacctgcg ccgtccacag accgccgatc agcaggacgt cgtacggtgc
      961 cggacggtgg aagccgatca gctgcgggcg gccttcggcg tcgtcaccga tgatcacccc
     1021 gtcgtccccc accggcaacg acagggcgcc caggtggtcc gccgccaggg tgtggccggc
     1081 atggcgcggg cccagcagcc ctcgcctcgg agcgatgtgc ttcgtcactg tgcgcctccc
     1141 agggggagcg tcgccaggac gcccggcagc tgctctcggt ccagccgtac gagcccgacc
     1201 tcggcgtgcc gtgcggcctg ctccaaagtc cttcgtacgc cgaccagttc ggtgtcggag
     1261 ccgccggtga tccgcacgtg gccgcgcacc gacacgtggc cctggtgcgc accgcggcgc
     1321 accgtcaggc tgaacgtcgt cgcgtacgcc ggcaccgacg tcagcagcga gacgagccgc
     1381 ggaagcggag tcgccccccg tcccagctcc ggccagcggt ccaccgcgta ggtggtgtgc
     1441 cagcggtcgt cgcagcgcca gacccgcggc gtctccgccg tacgccgctg cggcgcggca
     1501 tccgggcgtc cggcacgggc cgacaggatg gggttggcgc acgcggacgt cgccaccgcg
     1561 gagttcagct cctcctggtc cagcaccgag gcccggaacc ccgcaccggt gatccggctc
     1621 gccacatggt ccgcgacccg gaccaggcag cgctgagccc ctccgagccc gccaccgcgg
     1681 gcgtccacgg cctcccggca cagctccgga tccagcttca ccgccaccca ggtcatccgc
     1741 agcgcgggcg ccccggtccg gtcctgcagc ggggcgtacg agagccgggc caccgaccgc
     1801 tccggcagat gcggcgcagg ggcgggccgt acctgctgca cgagttgcgc ggactcgagc
     1861 acgatgtcgt ccaccgcgag agcgtcgccc aggagggaca gcgggagcgc ccgggcaccc
     1921 tgcgcctggc gaagcgattc accgctcgcc tcgacccgca cgaccgcggt caggaacgtg
     1981 ccgtccccga ccatgcccac cgtgcggcgg gcgccgtcca catagatgta cggagcgaat
     2041 cccggcacgc tctccgccac cggagccagt tgcggctccg tctcgacggg ggccgccacg
     2101 gccgaccggt tgcgacggcg gagggaggac accgtcgaga gccagtcctg caccgcccgg
     2161 ccccggcggc gtaccactgc gagaaggatg agcagacagg cgatcacgcc tgcgggaatg
     2221 agccacgcgc cgccgagcgc ggcacccacc acggccactg ccagggctgc ttcgacgagc
     2281 accatctgcc gcagcgcggg accgacgcgg ccggtcctgg agatcgaatg gagagtggtg
     2341 gccgctgggg cgtccgccga ccggtgggga gctgtgccgt ccgacccgtt gctgcgttgc
     2401 ctccgggaag ggcggggcgt tcggtgggtg gaccgcctcg cgcgttcccc cgtcgctgca
     2461 cccatcgccg cgttgccccc tcgtgtccgt attcaccgtt ttttgcacgg gcgttgatcg
     2521 ggcgatcacc ctacctgagc ggtgagagcc aagtgccaac aggcatagta ggggtcccgg
     2581 tcggcggcag cggtccacgg ccggtgtggg aacctggtcg cccacagggg agaaggggca
     2641 gcgcgcacat ggcatcacgg cgggacgaac tcaatgccta caccttcgcg aagcggaggt
     2701 tggtcgcaca gttcctgcag ccccacccgt ccggctcgga agagggggcg ccgcgtccgc
     2761 ttcgcgcggt ggttcccgga gtgatcgtcg gcgtggtcgt cctcgcggtg ttcggagcct
     2821 ggggcatgtt caagcccgta gcgccccaga agtgggacac cccctacgag aacgtcatca
     2881 tcgccagcaa gtccaccacc aggtacgtgg tgttgacgac cgacggcaag acacagctcc
     2941 acccggtgct gaacatgtcc agcgccaagc tcctcctcgc cccggacaag ggcaaggtcg
     3001 tcaacgtcga cgagtcggtc ctcgacagcg gcaagatccc gcacggggcg accctcggta
     3061 tcccgtacgc ccccgaccgc ctgccggaca agggcgaagc cggttccacg aagcgctggg
     3121 cggtctgcga gcggcccggc gagggcggca gggccatcca gaaggcggcg ttcgtcttcg
     3181 cggagcgcga gcagaagaag accgaaggcg cgaacaagct gcacggcggc gaggtgatgt
     3241 acgtcgaggg cccgggaccg gacaggaccc gctacatcgt ggacgccacg ggcaaggcgt
     3301 acccggtgga gaacaacgag ctgctgctgc gcaccctggt cgaccaggac cgtgtccccc
     3361 agcgggtgtc ggccgagtgg ctcgccacgc tgcacatggg cgacgaggtc accttcccgg
     3421 ccatcgaggg aactcccggc accgacgcgg gtgttccggg ggagctgcag cccgacgaca
     3481 acaaggtggg gatgatcctc gcggcgacct cggggacgag gacccagcag tacgtggtcc
     3541 tcaaggggag ggtcgccccg gtgtccgact tcgtcgccaa gctcctgctc agcagccgcg
     3601 acctggtcga cctcgagcag gacggcaagg cgaagtccgt cagcgccgga gcgttcgagc
     3661 ccggtgaggc cttcgggcag gaagcggact ggcccacgaa cgaggcgaca cccgtcaact
     3721 ccgcgagcgc ggcggacgga agccgtaaca ccgtgtgcaa cgtcctgcgc ggcgtatcgg
     3781 agaagaacgg caccagcacg ctcagcacct gggcgggcaa gggcttcccc gccaccctcc
     3841 ctaccggctc cagcagtgcc tacgtcaccc ccggatccgg tcagctcttc cggcagttca
     3901 agggttccag ccctgagtcc ggtcctctct tcctggtgac cgacacgggc ctgcgctatg
     3961 ccatgcagtc caacggcgac agcgcgcagg acgactccgg catcggtgag tccggcacga
     4021 aggaggaaag gaagcagagg cagcaggagg cgcagcaggc gcagatcaag ctgggttaca
     4081 aggacgtcga tcccgcaccc gtccccgccg actggtccgc cttcctgccg acgggccccc
     4141 gactgtcgac cggcgccgcg cgccagccgc agggttcgtg aggagcgaca cgtgaccacg
     4201 cagagcacgt ccactcgttc ccgtcgcctg ctgacagccg cggccgccac cggcgtcctc
     4261 ctcgtcacac tgccgatgcc catggcagcc gcggacgacg ccacccagtg caccttcccc
     4321 tcgaagaagt acgcgggccg cccctgggca ctgcaacgcg tgctgatgga cgagctgtgg
     4381 gagcagtcca ccggcaaggg cgtacgggtg gccgtcatcg acaccggcgt cgacgtcaag
     4441 aaccctcagc tcacgaaggc cgtggacacc gggagcggac gcaactacct ggacaagaac
     4501 ctgaaggacg agaacggcaa caagatcgag cgcggcaacg agaacggcac caccgacctg
     4561 gtcggccacg gcaccaaagt cgccggcatc atcgccgcgc gcgaggcgaa gggcaccggg
     4621 ttcaccggcc tggccccgga cgcgacgatc atcccgatcc agcagaacga cgccgagggc
     4681 cacgggacag cggaaacgct ggcggaggcc atccgttacg ccgccgggga gggaggcgcg
     4741 gacgtcatca acatctccca ggacacggcc aacgcggtgg agcccgcacc cgccctgaag
     4801 gaggcggtgg acgcggctct ggcccaggac atcgtgatcg tcgcctcggc gggcaacgac
     4861 gggctgggcg gaaacgtcaa ggagacctac ccggcctcgt tcgccggagt cctggccgtc
     4921 gccgcctcgg accgcaacaa cgagcgtgcg gccttctcgc agtccggcga cttcgtgggt
     4981 gtcgcggcac cgggggtgga catggtgtcc acggtccccg gcgggggaca ctgctccgac
     5041 aacggcacca gcttctcggc cccttacgtc gcgggggtcg cggcgctcat caaggccaag
     5101 cacaaggact ggacgcagga gcaaatcgtc gcccagatcc agcagacggc ggagcgctcg
     5161 accgcgggcc acgaccgact ggtcggctgg ggggtcgtcg acccggtgcg cgccctgacg
     5221 gaggacgaca aacccatcga gaaaccggtg gcacacgagg gcgtgagcaa gggcgaagcg
     5281 ccggtccccg ccgcgttcca cctgggtgag accgccgacg agcgcaacgc acggctagcg
     5341 acctatgtcg tggtgggcgg gggagtgctg gtcgccgcca tcgcgggaac ggccgtggcc
     5401 gtgcgcgaca ggcacaggcg gcaggggcgt cctggcggtt cgtgacggcc ggggcgcttg
     5461 acgccgggga agttacgtga tggacaagac agttggtcat gtcagtgcca ttggctagag
     5521 tgatgctatg aagccagggc tgttcacgcg agtgcgatag caacgcgaga cagactgtgc
     5581 aaacggggaa acggggaagg acagcaacgt ggccgaaggc aaaggcaatc tccggcgcgg
     5641 ggtaggcgcc ctggagaagt tccagaagag cgtgaacgcg ttgctggcgg agctcgagag
     5701 ttcaccggcc ggcaagtcga aggtcgcggc acagacggtg tcgcgtaccg ccttgagtgg
     5761 ccagaacaca tgcttcgcgg aagcggacgg gctctacacc cagtacaacc gggtccacga
     5821 gtcgctcgtc acgctctcga agtccctgag cgaccagatc gagtacctga acctcggcgt
     5881 gcacgcggcg gcggtcggct tcgacaacgt ggacgacgac acgcgacgac ggttccacga
     5941 gatccggacg cgcctcgaca aggagcacga gcaggcgcag ggcgagaaga cggtcaagcc
     6001 cgagcagaac gccgacaaga agagcgacgc ggggtgggca gccgaatgag tgaaccgaag
     6061 acgccggcac cgggtgctga ggcggagccg gaactgagcc ccgcggaaca gctgaagcag
     6121 gacgagggcc gcgtccaggg ccagttgatc gtcacggacg tcaaccgtgt ggtgcagggc
     6181 gtgatggagg tgttcggggg ctccggccct gcgggacgga cctccttcga aggccatgag
     6241 ctcaacgcga tgatcgacct gatcgagaac tccaagccgg aggatctcga agcggcgggc
     6301 aaggcgctct ggaacgccag gggagcgatc aaggacgcgg cgggcgaact gggacggttc
     6361 atcgagggcg tcgactggga gggcgaatcc gggaccgcct tccgcgactg gggtatggcc
     6421 ctggtcgccc atgccgacaa gctggccgtc ttcgcggaag tggccggcac ccagatcacc
     6481 gtcgcaggca cgggtctcgc ttcggtgcgt aactccctcc cgccccggga caaccgcctc
     6541 gtccgcaagt cccccgacga gatcgaggcc ccgaagcgga tcgagggcaa cgcggagtac
     6601 gaggcggcgg tgaaggtcga gaaggaccgc caggaggcca tcaaccaggc gaaccggctg
     6661 gcttcgtact acgcggtttc ggaggagacg ctggcggcgc agcagccgcc gcggttcgag
     6721 aagaagcttg atgtggagat gcccaggcct cagggctgga gtgacaggcc cgagtcaagc
     6781 cctgcaacgt cggcagcctc cgattcgtcg ggcagcggag ggctccagga tgcgacagtg
     6841 catggggcga cgggcagtcg gggttccgcg acaaacggtg acggctatga gccgcccgtg
     6901 gcggtggcgc ctgtcctgga caagggaacg tcgacagaga tcaatagcgt cgccaccccg
     6961 tcagccccgg tatctacccc aaacgcgcct tctccgggcc cgaccacgaa ccccgcacct
     7021 ggtggaggtc ctcctcccat ggcgtccggt ttcgtgaacc cagtgacgcg tagctcacga
     7081 ggaccccagg gggcaccagc gcccagagct gtcggccacg cgggggtcgg gggtgccaga
     7141 actaccggcc ctgcgggagg tggccctgcg gcgaacaccc gcgcaggatc cccggtgggg
     7201 cgccctccgg cccccatggg tgggggcccg gcctccggta cgtccgggcg tggtggtggt
     7261 gggccacagg ctcccactgc cggtcgcccc gctgttactg gcggcaggcc catggcagca
     7321 ggccacccag gtacgtccgg ggccaccggc ccttttgccg ggagggcggc cagcggcatc
     7381 gtaggcggaa ccccgcagcg cgccgttccg ggcgcgggtg cgcctggtgg cgctcgtggt
     7441 gtcccacgcg ggacggttat cggagcaggg ggagcggcgc gggccggtgg gcctgccggt
     7501 gttgggcagc gtggtgtcgt cggcggaggc acgggcagtg cgctccgtcc tggcgggcga
     7561 ggaactccca gcaccaacgg agttgtgggc acacctcgtg gaggccctgt gcgaccgggc
     7621 acaggcgcga aaggtttcac ccctggaggc gccggtctcg tgcgtggacc tgcaggccgc
     7681 aaggactcca gggatgaaga ccaggacgac ggcacgccgc gcccggacta cctgacggaa
     7741 gacagagaga cgtgggagac cggccggcgc ggaaccgcac cgccggtcat cgagtagatc
     7801 caggaagagt cggaagtcag gatgacagca gcaatgagcc agacccggag gcgccgtatg
     7861 cccggattgc gaaggcgcct gttcggcgct gtggctgtgg ccgctgcctg gagcgtggga
     7921 ttctccggga cggctccctc cgctgtcgcg gcggacgtgc agtcgaagca gtggtacctc
     7981 agcgcgatgc aggccgcaga gatgtggaag acggccaccg gtgaaggcat caagatcgct
     8041 gtcatcgata ccggcgtcaa ctcgtcgaca ccgtccctgg agggccaggt actcaagggg
     8101 cttgatgcaa ccggtgccga gggtgaagaa actgacgatt acgaaggcca cggcacgacg
     8161 atggctgagt tgattgcagg cactggtaag ggcggaggcc tgaagggcct tgctccagga
     8221 gcaaaaatca tcccgatgag agtcgccggt gcgaagtggc agactacgga aactctgaat
     8281 ccccacgata cgtcggatgc gattcgggcc gctgctgaca gcgatgcaaa aattatcagc
     8341 atgtctttcg gtaacgactt cgcgtcggat cgagaagaag aagctgtgaa gtatgcacaa
     8401 agcaagggga aattgttctt cgcttctgtt ggtaatgagg ccaagaacgg caacccggag
     8461 cgctatcctg ctgcgtacgc cgaagttgtc ggtgtctcct ctgcggaccg tgaaggaaaa
     8521 gtagcggagt actcccaaaa tgggcgcact gtggatatcg cggctcccgg aaacgatatt
     8581 ccgtactggt gcgacgccac gttcaagagc tattgcgatg gcgacggagg aaccagcgcg
     8641 gccaccgcca tcgcatctgc ctctgcggct ctgctctggt cggcccaccc cgactggact
     8701 gccaatcagg tactcaacgt tctcttcgac accgcgagcc gtgactggga aaagggaacg
     8761 ctcagcaagt acctcggcca cggcctgatc cgcccttcca tgaacatctt gaagggaaag
     8821 ggcacgcccg gtgcagcgga cgtcagcccg ctcaccaagg agaagacgcc cggttccgca
     8881 ggctcagccg ccccgtctgc atcagcctcg tcacagcctg agaagagcga gaaggctgac
     8941 gacgctgcca tggcaggctc cagcacggag aagaacgacg gcagccaact gggcctgatc
     9001 ctcggcggag tggccgtggt tctcgtactc ggcgtcggtg gtttcctgtt cgcgcgcagg
     9061 cgccgtaccg cctgacgggc cgtagtttct catatgtacc cccggcggga atgccggacc
     9121 gaagaagagc atcaggaagg aagccagcac catggcagat cagaagcttt cagatgacgc
     9181 gctcatcaag atcgagggcg agctctccac gcgattcgaa tccgtgaggg gccagatcaa
     9241 gacgctgcag gggacgatcg acagcctgga aggcgcgtgg aagggcatcg gcgccaccgc
     9301 cttcaacagc aagcaggatg agatcaaccg gaggatgggc aacatcgccg tccggatggc
     9361 caacttccag gaagccatca aggcggcccg cgtgatctcg ggcaacaccg aagacgagat
     9421 caaggcggcc ctccagggcg tcgacgtggt cgacggctac tcggccggcg cggaggccaa
     9481 gaccgcggcc atcacccctc cgccctcggc gctcaactcc ctctgagctt cgcctccgta
     9541 ctgcgtacgg accatcacat agaactagat tgaactggag gaccgtatgc cgaccaacga
     9601 cggcacgatg gttgtcactt atgcaagcct cgagcaggcc gctggtgaca tcgaccggca
     9661 gagcaggcag cttcaggagg acctcgcggc gatcaagcga gtggttgcca gtgcgtccga
     9721 actctgggtg ggcgaggcca agacggcgta cgacgcggcg caggccggct gggaccgtga
     9781 cgccacggcg attcagacgg ccctgaccga gatctcccgc aaggtgcgcg acgccggcat
     9841 ggcctaccag ggcggcgaca agcgggcgag ggccaacttc gagtaggact cgctgaagag
     9901 caaacaggtc agggtgggca cgcacgggag gtgcccaccc tgacctgtgt cgtgaggccg
     9961 gagtgctcgc gctctgccgg ccgcacgtct tcggttcagg tcactggtcc ttcaacaggg
    10021 tccaccacca ggcgacgctg gggatgggca ggggttggtc cgcctctctt tcgcgaaagg
    10081 gagaggcggc gctaccggcg gggaggtcgg cggggtcctc cggattgacg tagcgattgg
    10141 tggtgaggga ccagtcgtag tcggcacgga tccaggagtc gcagtccgtg atccaccggc
    10201 ggagttcgga gccggcgtcc cgcagtatct ggtcgcggag gcggaggtag agggtcatgg
    10261 cgcgggtgtg catcatggcg gtctcgctca ccgcctcgtc aagagagcat ttccgctcgt
    10321 acgcgatcag gtcgacgatg tttccgaagc tgtcttggct gcgttgccgc tccttgtggt
    10381 aggagatcag gtcgttggac cagccgatga tcgaggcgaa gacttcgacg aacccgcgga
    10441 tgtcgtggcg ctcgtagtcg gccgcgggga ggtcgtatcc gtggatgatc tcgctgagcg
    10501 tcgagaagat cttgaccccg gaggagtcga gccggaccgc cagatgatcc gagaggctgg
    10561 gaatccggcc gtgggcgctg ttggaggcca tccatatctg gccctggagg taggcccgga
    10621 agctggcggc ccagcgagcg gtctgcacgg gcgtggtcaa gtggtcgagt ctcaggcgca
    10681 actcgcgtag agcggcgctg tagctgtcgt cggcgggagc cgcccagggg acttcggcga
    10741 tgcgctgaag cttggtgatg atgagcaggg tggcatccgg ggacgctgcg acaggcccct
    10801 cgtcgcagaa ctcgtcgtcg aacgcgaaga gccacatcag gaagtccgac gtccactgca
    10861 aggccgcagg acgtccggcc ggggcgccac ggctggttat ctctcccacg gagatccgca
    10921 tcagccgttc gcgttgcgct cggtcggagt agaggccgaa ccgatcgagc caggcggcgg
    10981 agcgctcgtc gatctcacgc cagcccggat ggatccccga ggggagcgga acccacagct
    11041 gagggatctt cggcgctgga gctggggagg tcatgtaccg ccctttcacg ggtgcttctc
    11101 aatgcctctg agccccggaa gttagcaagg gtcacagcag gcgtgtacaa ccctttcaag
    11161 cctgcttggc ctacggacca ctgtccgtcc ccccacgggg ccggggcctc cgggcatgtc
    11221 ttcggcaccc gtgaaaggcg agaaagcggt tgatcgcgcc tcgattcagg ttgatcgtgc
    11281 gcagcgcggc gttggcccga aagtgactct tgccaggtgg ggattcaccg aatcggggga
    11341 ggagccccgg gctttgccgg cgccgggccc ggtaagcgcc cggttcaccg cgcctgacgc
    11401 ggagtggccg acccgggcag catggctcca gcaggaccgt ccgggacgga atattcacac
    11461 tgcggtggtg aatcgcctct gctgcgctcc ccatggaggc gactgggtac ggagaagggt
    11521 tgccgggccg ccgctccccg gccgtctcgg ctgcttctgc cgacggtcat gtgggttgat
    11581 ttcttcgtgg cccggcccac acgcagcaac gggcggtgac agaggcgtct cgcccactgt
    11641 caccgccctg cccgtcactg ccgcgtgtcg tgccgcgcgt cctacgcttc cccgtccatg
    11701 agcccggtct gcaccaacgg atttccgcgc cgccgggtga cgaagacccc gcgccccggg
    11761 ggcatcgggc gcggccggac gttgccgagc acgtccccct cgacggggtc gcccgacagc
    11821 atcacgccct gcgcccccag ctccaggatg cgctgcatga agggctcgta cagcgcacgg
    11881 cccgcacccg ccgtgctgcg ggcgatgatg aaccgcacgc cgacatcgcg ggagaacggc
    11941 agcatctccg tcagcttggc cagcgggttc ccgctggacg tcgacaccag gtcgtagtcg
    12001 tcgacgacca cgtacaccgt cggaccgctc caccagctgc ggtcacggag ttcctgggcc
    12061 gtgacctcgg gcgagggcgt acgacgcttc atcaggtcgt acagcgcgtc cgcgtggtgg
    12121 tccatgttgt tggacatggg cacgtactcc gccaggtgcg tggcgggggt gacgtcaagc
    12181 agcgctcgcc ggttgtcgat gacgaagaac ttcgcggcgt tcccgtcgta cctctcggtc
    12241 agctgcttga tgagcaggcg caggaggttg gacttgccgg actcgctctc gccgaacacc
    12301 aggaagaacg ggtcccgctc gaagtcgagg aagaccggct cgaggttgtt ctcgtcgata
    12361 ccgaacgcga tgccccgttc cggctgcgcg tagcccgcgg gcagctcgtg gaccgggagt
    12421 tcgcggggca gcagcctgac cgccggggcg ggagccgcgg tccagtgccg ggcgacctcc
    12481 gcgttcatcg ccgccgtggc ctcggagagg tcgctgtcgg agttgatgcc gtcgatgcgc
    12541 gggaccgcgg ccatgaagtg cagcttctcc ggcgtgagac cgcgtccggg tacgccgggg
    12601 ggcacgttga ccgcggcctt gcggtccagc tcggagtcca tgacgtctcc gagccgcagc
    12661 tcgagccggt tcatcaggtg gtccttcaga ttggcccgga cctccatcga acgcgacgcc
    12721 gtgacgatca ggtggatgcc gtagccgagg cctcgttggg cgatgtcgac ggctgccgat
    12781 tccaggccct cgtagtccga ccggaagttg ccccagccgt cgatgatcag gaagacgtcg
    12841 ccccacggct ggtccgtcac cgagatatcg ccacgggcgc gcagccttcg gaaggtggcg
    12901 atggagtcga tgccggcgct gcggaagtac tcctcacgcc gcgccatgat cccgtacacc
    12961 tcggagaccg tacggcgcac ccgttccggg tcgagccggg acgcgacccc tccgacatgg
    13021 ggcagaccgg agaccgaggc caggccgccg ccgccgaagt cgagcgcgta gaactggacc
    13081 tcgtggggcg tgtgggtgag ggcgaagccc gcgatgagcg agcgcaggag cgtggacttg
    13141 ccggactgcg ggccgccggt gatctgcatg tggcccgccg caccggagaa gtcccggtag
    13201 agcgtgtcgc ggcgctgctc gtacggcttg tcgaccacac ccagcggtgc gacgaggcgt
    13261 cccgatccct cgaacccggg ctgggtcagc ccacggccct cgaccgcgga gagccccgga
    13321 aggagctcgt cgaacgatgg cgggttgtcc agcggaggaa gccacacctg gtgtgcggaa
    13381 gcaccccggc cctccagccg gcgcacgatc acatcgagca ccgtgtccgc cagggcgtcg
    13441 tcctcggacg tacgcggctc gggtacaccg gtctgcgccg cgggctgtac gtagcgcacc
    13501 ggcaccggag ccgcggtgaa caccaccggc atgcggtcca cgggcagggg gccggaggac
    13561 gcggcccggc gtgcgcccga gcggtacacc ccggagacgt acgccgcctt gaagcggacc
    13621 atctcgtccg tgccgtactt caggtagccc gaaccaggga cgttgggcag gtggtacgcg
    13681 tcgggcacgc cgagcgcggc ccgggactcg cccgcggaga acgtacgcag accgatccgg
    13741 tacgacagat aggtctccag gccgcgcagc cgcccctctt cgaggcgctg cgaggccagc
    13801 agcagatgga cgcccagcga acggccgatg cgcccgatct gcacgaacat ctcgatgaag
    13861 tccggcttgg cggtgagcag ctcgctgaac tcgtcgatga ccaggacgag cgaggggatg
    13921 ggctgcagcg gggcacccgc cgctcgcgcc ttctcgtagt cgtggatgtt ggcgtagttg
    13981 cccgcgtcgc gcagcatctc ctggcggcgg ttgagttcgc cgctgatgga gtcgcccatg
    14041 cggtccacca gcgtcaggtc gtccgcgagg ttggtgatca ccgctgcgac atggggcatc
    14101 tgtgccatac cggcgaaggt ggcaccaccc ttgaagtccg cgaggacgaa gttgagcgtc
    14161 tccgaggtat gggtgacggc gaggcccagc acgagcgtgc ggagcagctc ggacttgccg
    14221 gaaccggtgg cgccgacaca caggccgtgc ggtcccatgc cctcctgcgc cgcctccttg
    14281 aggtccagca tcaccggcgc gccgtcctca cccacgccga tcggtacccg cagccgttcg
    14341 gcctgcgagc gggcccgcca ggtgcggctc acatcgacgg aggccgcgtc accgagattc
    14401 agcagatcgg tgaactccag attggcgagc agaggttcgt cgtcgtcccc gcccgtggcg
    14461 acgtggagcg gggccagttg ccgcgccagt gcctcggcgg cctcgtggct cagcaggtcg
    14521 gggagaccgt cgtagaccag gccgtgcccc gactccagct gcagcgagtg ggggtcgacc
    14581 acgatggaga ggccgccgcg cgccccgttg acctggcccg tgacgatctc gaccaccgtc
    14641 acgccctgga ggccctcggt cgacgcgagc gcggacgtcg cggggacgga ctcaccgtcg
    14701 agcacgacga cgacgtgcgg ctggtcgagg aggggctggc cgcccggctg gaagcggggc
    14761 ctgccgtcga ggtgtcccgc gagcatctcc tccagttccg cgacgctcgt gctgatcagg
    14821 cggcggctgc cggcgccgtc ggtggagccc cgcgcctgga cgtgcgggag ccacttcgtc
    14881 cagtcccagc gcggagcggc gtcgcggccg gtcgcgacgg cgatgatcag gtcctcgggg
    14941 gagtgcagcg aggcgagcga cccgatcatc gcgcgggcgg tggcgcgcgc ggactccccc
    15001 tcgccgctga tcgtcaggtg gtagaaggcc cggagggaga ccgccatcgg cagaccgtcc
    15061 agcgtgctgt gggtcgtcag gaactgctgc atcgccccgg cggtcagagg ctccagctca
    15121 tcgaccggcg cggtgtcggg tgcgacgagc ggagtcgcga gctcctggct gcccagaccg
    15181 atgcgtacgt gggcgaagtc cgcgtcaccg acacggcgct cccacagccg gctgccctcg
    15241 gcgacgagcg cccacagctg ctccggggac gggtggagat agaactgcgc gtcgcgctgc
    15301 tgccgggcgg tccggagtac ggcgcgtctg gtctgcgtca ggtacttcag atagtcgcgc
    15361 cgcatgtccg cgagctgacc ctgggtgccg cgccggaagc ggatgatcat cgcgatggcc
    15421 atcgcgatcg tcgacgcgat catgatcatg cccatgatcc gcatgatcgg gttcggcgtc
    15481 atgaagaaga agacgacgga accacccata ccgagcatcg gcagcagctg catcatcacc
    15541 ccctcctgct gcccgcgagg caactcgggc ggaggttgca actgcacctg ctcgcccgga
    15601 acttcggagg ggagggcccg cggtgggcgc ttgacgacaa tctggctcac agctcaccaa
    15661 ttcccttgcc ggacggaact gttcctatcg gcgcccccgt ggcgacgggt tccgtccgcg
    15721 ggaggatcct actggcgtac cccgtgaccc gagggcggta gggtgtcgcg acgcgtgtac
    15781 gcatccgcta actaccgcaa aaaaatgggt cattcgggac gcaggaagag cctgtggccc
    15841 aggggtgcgt ttccaggaga tcgcagcaga accacgaggg ggagcagcac gtgactatga
    15901 cggcccaaac ggcggctacc ggatccgggc ggccgggtcc cggagttccg gccggcaacg
    15961 gaaccggctt ctgccgggtc acggtcgtcg cgccggacag ccgcgtcgac gtggcgctgc
    16021 ccgaggacat ccccgtcgcc gacctctatc cggagatcct ccggctgtcg gggcagagcc
    16081 cggccccggg cgctccggtc ggctatcacc tcgtacgccg tgacggcacc gtcctcgaca
    16141 gcgggcgcac gctggccggc ctgcgcatcc tcgacggtga gctgctgtcc ctgcgcccct
    16201 tctcggagtc gctgcccccc gcggtcttcg acgacgtctc cgacgccgtc gccaccgccg
    16261 tcgcccggga ccgcaccctc tggggcgaca gcctcatgcg ctcggccggt ctcttcggcg
    16321 gctcggtcct gctggtcctg ctcggcttcg tgctgtggac ctccgacgtg cggcacgaca
    16381 tgcacggcct cccgggcatc ctcgccgccg tcagcgccct gctcctcctc gctctggcct
    16441 gcgtacgcgc gcgcgtctac gcggaccgcg gctcgtccat cgcgctgggg accggcgcac
    16501 tcgccaacgc cgcagtcgcc ggagccgggc tcctcccgct cggcgcgggc cagggcatcg
    16561 gcaggctcca gttcctgctc gcctgtgccg ccgtgctggt ggcgtcggtg atcctcatga
    16621 tcgccgcacc cgaaggtgac gggacgttcg tcgcgttcgt gttcgcctcg gtcatcggcg
    16681 cactggtcac cttcgtcgcg atcatgacgg gcatggagcc ggccgagacc gcggccgtgt
    16741 gtgcccccct ctccgtgggg ctcctcgcct tcctgcccgg gctgtccacc cgcttcgcgc
    16801 gcctcccgat cggcttcgag ccgccccgca ccaccgtcgg tgactacggg acgtccgacc
    16861 ccgcgcccca gggcccggtc gacgccgagc gcatcaccgc ccaggcgcgg cgcggccatg
    16921 aactgctcgt cggcctcgtc ggcggatgcg cgctggtcgc ggtgggagcc gcagcggtgc
    16981 tcggcttctc ggacagcgtc tggggccagc tgctggccct cgccaccggg gtcgcgatgc
    17041 tgatgcgcgc ccacctgttc cgctacacgg cccaggtcgg ctgcgccctg ggggcagggc
    17101 tcgccgcact cgtgcttctc ggcctcgggc tgtcgctcaa cccgccggtc gccctcgtga
    17161 aggaggcgtt cgccggggag accgcaggtc tcgacatccg tacgatctgg ctgaccgcag
    17221 cggtcgccgg ggtcgcggcc ctgatcacag ccataggcct gatcgtgccg cgcaagggcg
    17281 tcactccctt ctgggggcgc ttcctggaga tcgccgaggc ctgcgtgctc ctgacgctgc
    17341 tgccgctgtg cctcgctgtt ttcgacgtct accactcgat ccgggccctc accagctgac
    17401 acccgtcggg ggcgctccga acggctggta ctctgaccag tggccgtttg tgtacgcgtt
    17461 cccgggtcct cctgggggct gcgctcatcg gaccttcgcc tccgagtcat ggaagctccc
    17521 ctgagatcaa gaccaggggc actcgtgggc gcatcgaaca tcaagaggag tacgcgtgcc
    17581 gctcgacgcc gctacgaaga agcagatcat gtccgagttc gcccagaagg agggtgacac
    17641 cggatccccc gaggtccagg tcgccatgct ctcccgccgg atctcggacc tgacggagca
    17701 cctcaagacg cacaagcacg accaccactc ccgtcgtggt ctgctgatcc tggtcggcca
    17761 gcgtcgccgc ctccttcagt acctggccaa gaaggacatc cagcgcttcc gtgcgctcgt
    17821 cgaccgcctc ggcatccgcc gcggtgcggc cggcggcgcc aagtaaggac gctgtgggag
    17881 ggagcggtac cccggttcca gggggccgct ccctttgctg tacgtgcgtg acccgggtcc
    17941 ggctaagtaa cctggacgca caacaccaga acgaggagag gcgccccacg gccgccgccg
    18001 gtcctcggta gtggcccccg ggacaacgcc cgggagcttc gatcgaagac cggcccgcac
    18061 acacggtgcg cttctccgca ccgtcctccg ccacacgggc ggcaggacga aagacgacga
    18121 gtatggagaa atcactagtg gagaacgaga cccactacgc cgaagccgtg atcgacaacg
    18181 gtactttcgg cacccgcacc atccgcttcg agacgggccg cctggccaag caggccgccg
    18241 gctccgccgt cgcgtacctg gacgacgaca ccatggtgct ctcggccacc accgcttcca
    18301 agcggcccaa ggaccagctc gacttcttcc ccctcacggt ggacgtcgag gagcggcagt
    18361 acgcggccgg caagatcccc ggctccttct tccgccgtga gggccggccc tccgaggacg
    18421 cgatcctcac ctgccgcctg atcgaccgcc cgctgcgccc ctccttcaag aagggcctgc
    18481 gcaacgagat ccagatcgtc gagacgatca tggcgctcaa ccccgaccac ctgtacgacg
    18541 tggtcgcgat caacgccgcc tccgcctcca cgatcctggc gggcctgccc ttctccggcc
    18601 cgatcggcgc cacccgcgtc gccctgatca agggccagtg ggtcgccttc ccgacgcaca
    18661 ccgagctcga ggacgccgtc ttcgacatgg tcgtcgccgg ccgcgtcctg gaggacggcg
    18721 acgtcgcgat catgatggtc gaggccgagg ccaccgagaa gaccatccag ctcgtcaagg
    18781 acggcgccga ggccccgacc gaggaggtcg tcgccgccgg tctcgaggcc gcgaagccct
    18841 tcatcaaggc gctctgcaag gcccagtccg acctcgcctc caaggccgcc aagcccaccg
    18901 gcgagttccc ggtcttcctc gactaccagg acgacgtcct ggaggcgctc agcaaggccg
    18961 tcagcaccga gctcgccaag gcgctcacca tcgccggcaa gcaggagcgc gaggccgagc
    19021 tggaccgcat caaggagatc gcgggcgaga agctcctccc ggccttcgag ggccgcgaga
    19081 aggagatctc cggtgcctac cgcgcgctga ccaagaagct ggtccgcgag cgcgtcatca
    19141 aggacaaggt ccgcatcgac ggccgcggcg tcacggacat ccgtacgctc gccgccgagg
    19201 tcgaggccat cccgcgcgtg cacggctcgg cgctgttcga gcgtggcgag acccagatcc
    19261 tgggcgtcac caccctcaac atgctccgca tggagcagca gctggacacc ctctccccgg
    19321 tgacccgcaa gcgctacatg cacaactaca acttcccgcc gtactccgtc ggtgagaccg
    19381 gccgcgtggg ctcgcccaag cgccgcgaga tcggccacgg agcgctcgcc gagcgcgcca
    19441 tcgtgccggt gctgccgtcg cgcgaggagt tcccctacgc gatccgccag gtctccgagg
    19501 cgctgggctc caacggttcg acgtccatgg gctcggtctg cgcctccacc atgtcgctgc
    19561 tgaacgccgg tgtgcccctc aaggccgccg tcgccggtat cgccatgggt ctgatctccg
    19621 aggagatcga cggcaagacc cactacgtcg ccctcaccga catcctcggt gcggaggacg
    19681 ccttcggcga catggacttc aaggtcgccg gtacgaagca gttcgtgacc gcgctccagc
    19741 tcgacaccaa gctcgacggc atccccgcct cggtcctggc cgccgcgctg aagcaggccc
    19801 gtgacgcgcg tctgcacatc ctggacgtca tgaacgaggc catcgacgtc ccggacgaga
    19861 tgtccccgaa cgccccgcgg atcatcaccg tcaagatccc ggtggacaag atcggtgagg
    19921 tcatcggccc caagggcaag atgatcaacc agatccagga ggacaccggc gccgacatca
    19981 cgatcgagga cgacggcacc atctacatcg gtgcccagca gggctcgcag gccgaggccg
    20041 cccgcgccac gatcaacgcg atcgccaacc cgaccatgcc ggaggtcggc gagcgctacc
    20101 tgggtacggt cgtcaagacc acgaccttcg gtgcgttcgt ctccctgatg cccggcaagg
    20161 acggcctgct gcacatctcg cagatccgca agctcgccgg tggcaagcgc gtggagaacg
    20221 tcgaggacgt gctcgcggtc ggcgcgaagg tccaggtcga gatcgccgag atcgactccc
    20281 gcggcaagct ctccctgatc cccgtgatcg agggcgaaga ggccgacgag aagaaggacg
    20341 acaccgacaa gtgacgtccc gtagttccgt gacgacggcc cgcccctcct cggaggggcg
    20401 ggccgtcgcc cgtacccaaa cgcttctcaa gggcagcaac ggcatcggca cggtccgccg
    20461 taccgtcctc ccgggcggtc tccgggtcgt caccgagacg ctgccctccg tacgctccgc
    20521 caccttcggg atctgggcca acgtcggttc acgcgacgag acgcccaccc tgaacggcgc
    20581 gacgcactac ctggaacacc tcctcttcaa gggcacggcc aagcgcagcg ccctcgacat
    20641 ctcgtccgcg atcgacgcgg tcggcggcga gatgaacgcc ttcacggcga aggagtacac
    20701 ctgctactac gcgcgggtcc tggacaccga cctgccgctg gccatcgatg tcgtgtgcga
    20761 catgctgacc ggatccctga tcgcccccga ggacgtcgac gccgagcgcg gcgtcatcct
    20821 cgaggagatc gcgatgacgg aggacgaccc gggcgactgc gtgcacgacc tgttcgcgca
    20881 caccatgctc ggcgacaccc cgctgggccg cccggtcctc ggcaccgtcg acacgatcaa
    20941 cgcgctgaac cgcggccaga tcgcccgctt ctacaagaag cactacgacc ccacgcacct
    21001 ggtcgtcgcc gccgccggca acgtcgacca cgccacggtc gtgcgacagg tccgcaaggc
    21061 gttcgagcgc gccg
//
