LOCUS       NZ_CABVIY010000010     22169 bp    DNA     linear   CON 07-NOV-2023
DEFINITION  Pseudomonas fluorescens isolate PS918, whole genome shotgun
            sequence.
ACCESSION   NZ_CABVIY010000010
VERSION     NZ_CABVIY010000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Pseudomonas fluorescens
  ORGANISM  Pseudomonas fluorescens
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
REFERENCE   1
  AUTHORS   Chandra,G. and Truman W,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2019) JOHN INNES CENTRE, NORWICH, UK., Molecular
            Microbiology, Norwich Research Park, Norwich NR4 7UH, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/07/2023 08:57:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,059
            CDSs (total)                      :: 5,986
            Genes (coding)                    :: 5,920
            CDSs (with protein)               :: 5,920
            Genes (RNA)                       :: 73
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 7 of 66
            Pseudo Genes (incomplete)         :: 63 of 66
            Pseudo Genes (internal stop)      :: 6 of 66
            Pseudo Genes (multiple problems)  :: 8 of 66
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:35:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 58895
            Orig. end                         :: 81064
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CABVIY010000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22169
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="1"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22169
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22169
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12169](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12169
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     misc_feature    24..33
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     misc_feature    complement(341..356)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.02"
                     /tool="antismash"
     gene            complement(483..2837)
                     /locus_tag="F8N66_RS29930"
                     /old_locus_tag="PS918_05723"
     CDS             complement(483..2837)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016704067.1"
                     /locus_tag="F8N66_RS29930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05723"
                     /product="glucose/quinate/shikimate family membrane-bound
                     PQQ-dependent dehydrogenase"
                     /protein_id="WP_150773504.1"
                     /transl_table=11
                     /translation="MNNSGAAAGSKWLLAGLGVLIALIGLGLVGGGGYLITLGGSAYFL
                     LMGLAMLVSGVMIARRKPQGAWLYGLALILTAIWAVWDAGFEYWPLVSRVLTFAVIGLV
                     VALIYPTLVRASGATAGRGAYGLAGILGVGVVATMAYMFVPTHVVKASSEPTVTPVAPG
                     TEQKDWAHWGNTTAGNRFAALDQINKGNIDKLQVAWTFRTGDIPQSTGAGAEDQNTPLQ
                     IGDTVYTCTAYGKVFALDVDTGAQRWKFDPQGTAPNWQRCRGLGYSETPASSDNQPTAC
                     KKRLFLPTGDARLIAINAETGKPCEAFGNQGTVDLTTDMGEVKPGYYQQTSTPLVAGDV
                     VIVGGRVADNYSTGEPPGVVRAYDVRSGELVWAWDPGNPNTTKRPPAGETYTRGTPNVW
                     SAMSYDAKLGLVYLPTGNATPDFFGGQRTEFDDKWSSSIVAIDVKTGQVRWHFQTTHHD
                     LWDFDLPAQPLLYDVPDDKGGLQPALAQVTKQGEIFLLNRETGVPIARVEERPVPQGSV
                     PGERYSPTQPFSVDMPSIGNKTLTEADMWGATPFDQLMCRIQFKGMRHEGVYTPPGMDR
                     ALQFPGSLGGMNWGSVSVDPNSHYMFVNDMRLGLANYMIPRDKIGAGASGIEMGVVPQE
                     GTPFGAMRERFLSAVGIPCQKPPFGTMSAIDLKTHKLMWQVPVGTVQDTGPLGIRMHLP
                     IPIGMPTLGASLATQSGLLFFAGTQDFYLRAFDTGNGNEIWKSRLPVGSQSGPMTYVSP
                     KTGKQYILLTVGGARQSTDRGDYVIAYALPK"
     gene            2981..3442
                     /locus_tag="F8N66_RS29935"
                     /old_locus_tag="PS918_05724"
     CDS             2981..3442
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020798842.1"
                     /locus_tag="F8N66_RS29935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05724"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_007980298.1"
                     /transl_table=11
                     /translation="MPDTRPPVLDEIDRQLIAALQINARESVAMLARQLGIARTTVTSR
                     LARLEKAKVITGYGVRLGQRVVDGGLQAYVGITVQPRSGKEVLRRLSAMAQVQQLCAVS
                     GEFDYVAWLRTDSPEQLDQLLDQIGSVDGVEKTTTSIILSSKIDRGQPV"
     gene            3702..5384
                     /locus_tag="F8N66_RS29940"
                     /old_locus_tag="PS918_05725"
     CDS             3702..5384
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008147187.1"
                     /locus_tag="F8N66_RS29940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05725"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_150773505.1"
                     /transl_table=11
                     /translation="MNKNNRHPADGKKPVTIFGPDFPFAFDDWIEHPAGLGSIPEHHHG
                     AEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKLGGRLRSQAFNGTDGIVAELGGMRFP
                     VSSTAFYHYVDKLGLETKPFPNPLTPASGSTVIDLEGKTHYAQKLADLPALFQEVADAW
                     ADALEAGSQFSDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFHHR
                     EVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCV
                     HWPQGTSLKSLHSGAPRSGVKKIAHAPGGRFAVTDNNGDTREYAAVLTTCQSWLLTTQI
                     ECDESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPQTGCDLMSMTLTDRLTRGT
                     YLFDNGDDKPGVICLSYSWMSDALKMLPHPVEKRVKLALDALKKIYPKVDIAARIIGDP
                     ITVSWEADPHFLGAFKGALPGHYRYNQRMYAHFMQDDMPPEQRGIFIAGDDVSWTPAWV
                     EGAVQTSLNAVWGIMKHFGGVTHKENPGPGDVFKDIGPIALPE"
     gene            5397..6191
                     /locus_tag="F8N66_RS29945"
                     /old_locus_tag="PS918_05726"
     CDS             5397..6191
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007947815.1"
                     /locus_tag="F8N66_RS29945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05726"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_150773506.1"
                     /transl_table=11
                     /translation="MRVALYQCPPLPLDVPGNLQRLQQLAQEAKGADLLVLPEMFLTGY
                     NIGVDAVSVLAEVHNGESAQQVARIARAAGIAILYGYPERTEDGQIYNAVQLIDAEGER
                     VCNYRKTHLFGDLDRSMFSPGTNQFPVVELNGWKLGFLICYDLEFPENARRLAIEGAEL
                     ILVPTANMIPFDFIADVTVRSRAFENQCYVAYANYCGQEGDIQYCGQSSIAAPDGSRIA
                     QAGLDEALIVGELNRQLMADSRGANRYLIDRRPELYGALNKR"
     gene            6230..8659
                     /gene="pqqF"
                     /locus_tag="F8N66_RS29950"
                     /old_locus_tag="PS918_05727"
     CDS             6230..8659
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007936525.1"
                     /locus_tag="F8N66_RS29950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05727"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqF"
                     /protein_id="WP_150773507.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 8.8e-36, bitscore:
                     117.3, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1.4e-11,
                     bitscore: 38.9, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPALNPPHPHTETLANGLRVTLRHAPDLKRCAAVLRVAAGSHDVP
                     LAWPGLAHFLEHLLFLGTERFALEQGLMAYVQRHGGQLNARTHERTTDYFFELPPQAFA
                     GGLERLSDMLAHPRMNLEDQQREREVLQAEFVAWSQDATAQQQLALFDGLSPQHPLRGF
                     HAGNRDSLPVEQPAFQQALQGFYQQFYQAGQMTLSLVGPQPLEALKALAQEFADALPEG
                     EKVPRQAPVALMDTLTKSYQQPHERRLDLLFAFETLPERSPEALAFLCHWLNNAKSGGL
                     LAELRSRGWADSLKAAPLYQFAGQALLHIECTLNADAQPSAIHHLLLDWLGFFARQEWS
                     GLRDEYTALLQRQQHVSGALQLARLDSEQHEAGLSGQGVTALKDVLQQIGAVDNFTGPW
                     QLPAPNPFLRSEAPAPNAGLIRGQTSAHRGLRTFAQDRSRSRRERSPMQFSQALPDNTA
                     EGAVYVRWRLEYAPGSHVQAHLDNGLHPLREDARQAGVDLSFGASGNEWLLKMTGLQEP
                     MPIILEHALKELTKPGGDFSQEQSTSVALMPIRQLLKVLPGLCLERSPESQSLQQLWAS
                     ARWDGLATGLSAQTQAAMGLALSRIPGTADNQLTPPPSIRSHCLWSHVETGSSEHALLL
                     FCPTATDDIASESAWRLLAHLAQTPFYQRLRVELQLGYAVFSGLRQLHGQTGLLFGVQS
                     PSVTPPVLLQHIEQFLNGLPDMLRDMDDGHFTALRHTLADQFACGALPNAQAAELLWHG
                     KLAGRSSDFLTQLPEAILSVDRPALIDAARRLIQAEGGWRCLSSGPCPGAPWQVTK"
     misc_feature    complement(8714..8728)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.62"
                     /tool="antismash"
     gene            8815..8889
                     /gene="pqqA"
                     /locus_tag="F8N66_RS29955"
     CDS             8815..8889
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003444522.1"
                     /locus_tag="F8N66_RS29955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_003194766.1"
                     /transl_table=11
                     /translation="MTWSKPAYTDLRIGFEVTMYFASR"
     gene            8963..9874
                     /gene="pqqB"
                     /locus_tag="F8N66_RS29960"
                     /old_locus_tag="PS918_05728"
     CDS             8963..9874
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017701795.1"
                     /locus_tag="F8N66_RS29960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05728"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_150773508.1"
                     /transl_table=11
                     /translation="MFVQILGSAAGGGFPQWNCNCVNCAGFRDGSLRAKARTQSSIAIS
                     DDGVNWVLCNTSPDIRAQLQSFAPMQPGRALRDTGISAIILMDSQIDHTTGLLMLREGC
                     PHQVWCTDMVHEDLSSGFPLFNMLTHWNGGLSWNRIELDQSFSIPACPNLRFTPLPLRS
                     AAPPYSPHRFDPHPGDNIGLIVEDLNTGGKLFYAPGLGKVDAPLLEIMAGSDCLLVDGT
                     LWDDDEMQRRGVGTRTGREMGHLAQNGPGGMLEVLEQLPKQRKVLIHINNTNPILDEDS
                     PQRAELDRRGVEVAYDGMSIVL"
     gene            10001..10753
                     /gene="pqqC"
                     /locus_tag="F8N66_RS29965"
                     /old_locus_tag="PS918_05729"
     CDS             10001..10753
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007926092.1"
                     /locus_tag="F8N66_RS29965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05729"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_150773509.1"
                     /sec_met_domain="TIGR02111 (E-value: 2.5e-128, bitscore:
                     420.5, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTPMSPAEFEAALRAKGAYYHIHHPYHVAMYEGRATREQIQGW
                     VANRFYYQVNIPLKDAAILANCPDREIRREWIQRLLDHDGAPGEDGGIEAWLRLGQAVG
                     LDPDQLRSQELVLPGVRFAVDAYVNFARRASWQEAASSSLTELFAPQIHQSRLDSWPQH
                     YPWIDPAGYAYFRTRLGQARRDVEHGLAITLQHYTTQAGQERMLEILQFKLDILWSMLD
                     AMSMAYELKRPPYHSVTEQRVWHKGITL"
     gene            10750..11025
                     /gene="pqqD"
                     /locus_tag="F8N66_RS29970"
                     /old_locus_tag="PS918_05730"
     CDS             10750..11025
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004419445.1"
                     /locus_tag="F8N66_RS29970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05730"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_150758522.1"
                     /sec_met_domain="PqqD_RRE (E-value: 6.8e-36, bitscore:
                     116.1, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.6e-16, bitscore: 53.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFDRSKTPTWRPGYRFQYEPAQKGHVLLYPEGMIKLNESAALIG
                     GLIDGQRDVAAIITELDQQFPGVPELGDDIEQFMEVARAQHWIELA"
     aSDomain        10753..11019
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_F8N66_RS29970_PqqD_RRE.1"
                     /evalue="6.70E-37"
                     /identifier="RREFam006.1"
                     /label="F8N66_RS29970"
                     /locus_tag="F8N66_RS29970"
                     /protein_end="90"
                     /protein_start="1"
                     /score="116.1"
                     /tool="antismash"
                     /translation="SFDRSKTPTWRPGYRFQYEPAQKGHVLLYPEGMIKLNESAALIGG
                     LIDGQRDVAAIITELDQQFPGVPELGDDIEQFMEVARAQHWIEL"
     gene            10997..12169
                     /gene="pqqE"
                     /locus_tag="F8N66_RS29975"
                     /old_locus_tag="PS918_05731"
     CDS             10997..12169
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007936504.1"
                     /locus_tag="F8N66_RS29975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05731"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_150773510.1"
                     /sec_met_domain="PTHR43273 (E-value: 1.5e-30, bitscore:
                     100.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.1e-25, bitscore: 85.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.6e-09, bitscore: 31.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.9e-10, bitscore: 34.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.4e-09, bitscore:
                     29.7, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSTGSNLPDSSVQVPPKPDIGLPLWLLAELTYRCPLQCPYCSNP
                     LDFAEQGKELSTEQWIKVFREAREMGAAQLGFSGGEPLVRQDLAELIAEARQLGFYTNL
                     ITSGIGLTEQKISDFKKAGLDHIQISFQASDEQVNNLLAGSKKAFAQKLEMARAVKAHG
                     YPMVLNFVTHRHNIDRIDRIIELCIALEADFVELATCQFYGWAQLNRVGLLPTKEQLVR
                     AERITNEYRARLEAQGHPCKLIFVTPDYYEERPKACMNGWGSIFLTVTPDGTALPCHGA
                     RQMPVQFPNVRDHSMQHIWYDSFGFNRFRGYDWMPEPCRSCDEKEKDFGGCRCQAFMLT
                     GDASNADPVCSKSHHHGVILAAREEAEHATQTIGQLAFRNERNSRLIAKS"
     gene            12135..13961
                     /locus_tag="F8N66_RS29980"
                     /old_locus_tag="PS918_05732"
     CDS             12135..13961
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007999152.1"
                     /locus_tag="F8N66_RS29980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05732"
                     /product="S9 family peptidase"
                     /protein_id="WP_150773511.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 5.7e-47, bitscore:
                     154.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEIHASSPKAEPFSAARAVAAGIDFAELQVGQQGLFWNEYRPED
                     AACRLWHWRDGVAKCLTPPGFSVRSRVYEYGGGAFCLTDDGVVFVNEADQQLYRQSFQG
                     EAPEVLTTGVCRYGDLQFASGQVLAVEENRDRHRLVAIDLADGKRHVLAEGADFYAAPT
                     LSPDVQRLAWIEWSRPDQPWTATRLMVAERQRDGGFGPGRCVAGDDAQESLQQPRFDNR
                     GRLGCLTDRGGYWQPWLESASGLTPLPSAAADHGPAPWQLGGCTWLPLTDDRYLASWTE
                     GGFGRLGLWSGAVEEFAGDYTRFRSLAVDAQCIYCIAASPVSSSAVIAIDRQTRQVKVL
                     AGGIAPLPAEQVSRPQTLCYPSGAGQAHGFFYPAMTGEAKPPLVVFIHGGPTSACYPML
                     DPRIQYWAQRGFAVADLNYRGSSGYGRAYRQALHLSWGEVDVEDACAVVSHLAERGLID
                     GDNAFIRGGSAGGYTTLCALAFRSVFRAGASLYGVSDPVALGRATHKFEGDYLDWLIGD
                     PVQDAERYAARTPLLHAGNIRVPVIFFQGELDAVVVPQQTRDMVEALHNNGIAVQAHYY
                     ADERHGFRKAGNQAHALEQEWLFYRRVMDQLD"
     gene            complement(14079..14237)
                     /locus_tag="F8N66_RS29985"
                     /old_locus_tag="PS918_05733"
     CDS             complement(14079..14237)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_249258.1"
                     /locus_tag="F8N66_RS29985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05733"
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="WP_003228885.1"
                     /transl_table=11
                     /translation="MDFIRIIIAILLPPLGVFLQVGFGGAFWLNILLTLCGYIPGIVHA
                     VYIIAKR"
     gene            complement(14322..14642)
                     /locus_tag="F8N66_RS29990"
                     /old_locus_tag="PS918_05734"
     CDS             complement(14322..14642)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007980317.1"
                     /locus_tag="F8N66_RS29990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05734"
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="WP_150773512.1"
                     /transl_table=11
                     /translation="MSKKFKSEIAESIHESASALFAIGAITKATMREFDESCLATVPDA
                     IPAEQIKALRERNNVSQPVFARYLNTSASTVKQWEAGDKHPSGMALKLLSIVQKHGLEI
                     LA"
     gene            complement(14635..14991)
                     /locus_tag="F8N66_RS29995"
                     /old_locus_tag="PS918_05735"
     CDS             complement(14635..14991)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007910060.1"
                     /locus_tag="F8N66_RS29995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05735"
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_150773513.1"
                     /transl_table=11
                     /translation="MSPRLFKTKRFAMQAAKAWIGDDELREAFAEMLNGQADNLGGDVW
                     KKRLNANRHRSILLAKGGRYWVYQFLYAKKDQSNITPRHLADLRELAKTSGGLSEMGIQ
                     RLLDMREFVEIRYE"
     misc_feature    complement(15013..15029)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 23.5"
                     /tool="antismash"
     misc_feature    complement(15014..15029)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: medium, score: 25.46"
                     /tool="antismash"
     misc_feature    15133..15145
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.6"
                     /tool="antismash"
     gene            complement(15244..16527)
                     /locus_tag="F8N66_RS30000"
                     /old_locus_tag="PS918_05736"
     CDS             complement(15244..16527)
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (45-360). E-value: 1.1e-79.
                     Score: 259.9. Matches aSDomain:
                     nrpspksdomains_F8N66_RS30000_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020796022.1"
                     /locus_tag="F8N66_RS30000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05736"
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_150773514.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.4e-85, bitscore:
                     281.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLFNLRRHSPSLDDLVADASFASGDDILASECLMPSVERPQQVF
                     VRGQGSWLWDSEDRAYLDFSQGGGANSLGHSPKALVNAITAQARSLINPGFGLHNRGML
                     NLAERLCLSTGSDQAYLLNTGSEACEAAIKLARKWGQQHRGGASRIIVASNGCHGRSLG
                     TMSASDSSTLINRFEPQLPGFSPVPFNDLPALHAAVDERTVAIMLEPIQNAAGVIPATA
                     HYLRGVERLCRELGILLILDEVQTGIGRCGTVLAEQSYGVRADIVVLGKGLGGGVPLAA
                     LLARGKACCFDSGEMSGTHHGNALMTMAGLAVLDSVQDKGFLDHIGETAQHLREGLQRL
                     SHRYGHGELRGQGLLWGLTLSDDCAEAVVKAALYEGLLLDAPQPDVLRFTPALTVSKAN
                     IDEMLLRLARAFSRVRTAQLQCRKGIAV"
     aSDomain        complement(15448..16392)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F8N66_RS30000_Aminotran_3.1"
                     /evalue="1.10E-79"
                     /label="F8N66_RS30000_Aminotran_3.1"
                     /locus_tag="F8N66_RS30000"
                     /protein_end="360"
                     /protein_start="45"
                     /score="259.9"
                     /tool="antismash"
                     /translation="VRGQGSWLWDSEDRAYLDFSQGGGANSLGHSPKALVNAITAQARS
                     LINPGFGLHNRGMLNLAERLCLSTGSDQAYLLNTGSEACEAAIKLARKWGQQHRGGASR
                     IIVASNGCHGRSLGTMSASDSSTLINRFEPQLPGFSPVPFNDLPALHAAVDERTVAIML
                     EPIQNAAGVIPATAHYLRGVERLCRELGILLILDEVQTGIGRCGTVLAEQSYGVRADIV
                     VLGKGLGGGVPLAALLARGKACCFDSGEMSGTHHGNALMTMAGLAVLDSVQDKGFLDHI
                     GETAQHLREGLQRLSHRYGHGELRGQGLLWGLTL"
     misc_feature    16556..16571
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.38"
                     /tool="antismash"
     gene            16697..17626
                     /locus_tag="F8N66_RS30005"
                     /old_locus_tag="PS918_05737"
     CDS             16697..17626
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015097090.1"
                     /locus_tag="F8N66_RS30005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05737"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_150773515.1"
                     /transl_table=11
                     /translation="MDFKQLRYFVAVYEEGHVGRAAERLSISQPALSQQIRHLEQTLDV
                     SLFERSSKRLLPTLAAHTLYNHALPLLDGLQRAREALGNFKGQALRTLAIGVLQTVHTS
                     LVPQMLERVRKAQPHLVVQIYELTGLEIERRLLNGSLDIGISYLPPRQPGLHGVMLYED
                     ELTLVIPAEHPLREFKKVSMKQAAELPMLLLGEEFQVRQIWQAQLANLGRRPQVQAELN
                     NMAGILDSLPHTRLATVLPGRSQKAHGNKDLLWKPLSEPRVPLKVGLVCRDVQRQQASL
                     ALLRTLLEEVMNQPDERLNSTSERDGLS"
     gene            complement(17854..19632)
                     /locus_tag="F8N66_RS30010"
                     /old_locus_tag="PS918_05738"
     CDS             complement(17854..19632)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_249199.1"
                     /locus_tag="F8N66_RS30010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05738"
                     /product="acyl-CoA dehydrogenase C-terminal
                     domain-containing protein"
                     /protein_id="WP_150773516.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.1e-13, bitscore:
                     45.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.4e-17, bitscore:
                     57.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5e-23, bitscore:
                     76.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADYKAPLRDMRFVLNEVFEVAKLWAELPALADTVDAETVEAILE
                     EAGKVTSKSIAPLSRAADEEGCHWADGAVTTPAGFPQAYQTYAEGGWVGVGGDPAYGGM
                     GMPKAVSAQVEEMVNSASLSFGLYPMLTAGACLSINAHASDELKAAYLPNMYAGVWAGS
                     MCLTEPHAGTDLGIIRTKAEPQADGSYKVSGTKIFITGGEHDLTENIIHLVLAKLPDAP
                     AGPKGISLFLVPKFMVNADGSLGARNPANCGSIEHKMGIQASATCVMNFDEAVGYLVGE
                     PNKGLAAMFTMMNYERLGVGIQGLASGERSYQNAVEYARDRLQSRSPTGAQNKDKVADP
                     IIVHPDVRRMLLTMKASNEGGRAFSTYVAMQLDTAKFSEDATTRKRAEDLVALLTPVAK
                     AFLTDLGLETTVHGQQVFGGHGYIREWGQEQLVRDVRITQIYEGTNGIQALDLVGRKIV
                     GSGGAFYNLFADEIRHFTATASADLAEFTKPLNDAVTTLDELTAWLLDRAKNNPNEIGA
                     ASVEYLQAFGYTAYAYMWALMAKAALGKEAQDDFYASKLGTARFYFARLLPRIHSLSAS
                     VKAGSESLFLLDAAQF"
     misc_feature    19742..19758
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.33"
                     /tool="antismash"
     gene            complement(19877..21673)
                     /locus_tag="F8N66_RS30015"
                     /old_locus_tag="PS918_05739"
     CDS             complement(19877..21673)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_249198.1"
                     /locus_tag="F8N66_RS30015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05739"
                     /product="acyl-CoA dehydrogenase C-terminal
                     domain-containing protein"
                     /protein_id="WP_150773517.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 4.2e-15, bitscore:
                     50.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.3e-19, bitscore:
                     64.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.8e-26, bitscore:
                     87.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEYKAPLRDMRFLIDHVFDFHSHYAALGANDASPDMINAILEEG
                     AKFCENVLSPLNRSGDEEGCHFDNGVVTTPAGFKQAFAQYVEGGWHGLAADPAYGGQGL
                     PSSLGLVISEMVASSNTSWGMYPGLTHGAMSAIHAHGTDAQKQTYLSKLTAGQWTGTMC
                     LTEAHCGTDLGIIKTRAVPQADGSYAISGSKIFISAGEHDMSDNIIHLVLAKLPDAPAG
                     TKGISLFIVPKFLPDAAGEAGARNGVSCGSIEHKMGIKASATCVLNFDGAQGFLIGEAN
                     KGLNCMFTMMNHARLGTGMQGLCLGEASFQGAIKYANERLQMRALTGPKAPEKAADPII
                     VHPDVRRMLLTMKAFNEGNRALTYFTAQLLDTAHLSADAAARQDAEDLLAFLTPICKAF
                     MTETGLEVTNHGMQVFGGHGFIREWGMEQLVRDCRIAPIYEGTNGIQALDLLGRKVLGS
                     QGKLLRGFTRIVHKFCLANAAHPQLAVHVAQLNDLNRQWGELTTRVGMAAMNNPDEVGA
                     ASVDYLMYSGYIILGYLWLRMALVAQARLEEGSGDADFCRAKLATSEFYFKRLLPRTEA
                     HRAGIEAGSDCLMQLPAELFAL"
ORIGIN
        1 gcgcagcagg tgtcgcagct ccctgatttt tgcgtcatcg cgttccgcgc cgaacgcgcc
       61 attgaggatg gcggcggctt gcgatgtatc gacacgtttc ttgcgcgcag gggttgaagg
      121 taatgtctgc gccatcgcgc cggcgaacag gacaatgatc cgggcttcca gatagtcctt
      181 catcgcctgc atcgaggcga ttgaacgggc cagggtgatg caagcgcccc ctttatgcct
      241 aaggtccatg gtcacggcca gggtcacgcc acccgtttca aaccccaggg tccgggccac
      301 ggcatagtga cccatttcat gatgggcgat ctgcagggca tgttcgcgca cagcggcagg
      361 catcttcttc acatgcatcg cgtcggatct cccgttcgac tacgaatgac tgtaactgcc
      421 ctgaatcttc acacaaaaaa gccgtgcaat cgcacggctt tttctttcct gcctgtcagc
      481 ctttatttgg gcaaggcata ggcaatcaca tagtccccac ggtccgtcga ctgacgcgca
      541 ccgcccaccg tcagcaggat gtactgcttg ccggttttcg gcgagacgta ggtcatcggc
      601 ccggactggc tgcccactgg caggcgtgac ttccagattt cattgccgtt gccggtatcg
      661 aaggcgcgca ggtagaaatc ctgggtgccg gcgaagaaca gcaggcccga ctgggtggcc
      721 agcgaggcgc cgagggtcgg catgccgatc gggattggca ggtgcatgcg gatgcccaac
      781 gggccggtat cctgcacggt gccgaccggg acttgccaca tcagtttgtg ggtcttgagg
      841 tcgatggcgg acatggtgcc gaacggtggt ttctggcagg gaatgccgac cgccgagagg
      901 aagcgttcgc gcatggcgcc gaacggcgtg ccttcctgcg gtacgacgcc catttcgata
      961 ccactggccc cggcgccgat cttgtcacgg gggatcatgt agttggccag gcccaggcgc
     1021 atgtcgttga cgaacatgta gtggctgttc ggatcgaccg agacgctgcc ccagttcatg
     1081 ccgcccaacg aacccgggaa ttgcagggca cggtccatgc ccggcggcgt gtagacgcct
     1141 tcgtggcgca tgcccttgaa ctggatgcgg cacatcagct ggtcgaatgg cgtggcgccc
     1201 cacatgtcgg cttcggtcag ggttttattg ccgatggacg gcatgtccac cgagaacggc
     1261 tgggtgggcg agtagcgttc gccgggcacg ctgccctgtg gcaccgggcg ctcttcgaca
     1321 cgtgcgatgg gcacgccggt ttcacggttg agcaggaaga tctcgccctg tttggtgact
     1381 tgcgccaagg ccggttgcag gccgcccttg tcgtccggca cgtcgtacag cagcggctgg
     1441 gcgggcaggt cgaagtccca caggtcgtgg tgagtggtct ggaagtgcca gcgcacctgg
     1501 ccggtcttca cgtcgatggc gacgatggac gaactccatt tgtcatcgaa ctcggtgcgt
     1561 tgaccgccga aaaagtccgg ggtggcgtta ccggtcggca ggtacaccag gccgagtttg
     1621 gcgtcgtagg acatggccga ccagacgttc ggcgtgccac gggtataggt ctcgccggcc
     1681 ggcgggcgtt tggtggtgtt cgggttgccc ggatcccacg cccataccag ctcaccgcta
     1741 cgcacgtcgt aggcacggac cacaccgggc ggttcgccgg tggagtagtt atcggccacg
     1801 cgaccaccga cgatcaccac atcacccgcg accaatggcg tcgaggtttg ctggtaataa
     1861 ccgggcttca cttcgcccat gtcggtggtc aggtcgacgg tgccctggtt gccgaacgct
     1921 tcacacggct tgccggtttc ggcattgatg gcgatcaggc gggcatcgcc ggtcggcaga
     1981 aacagacgtt tcttacaggc tgttggctgg ttgtctgaag acgcaggggt ttcggaataa
     2041 cccaggccac ggcagcgctg ccaattgggc gcggtgcctt gcgggtcgaa cttccagcgc
     2101 tgggcaccgg tatcgacgtc cagggcgaag accttgccgt aggccgtgca cgtgtagacc
     2161 gtatcgccga tttgcagcgg ggtgttctgg tcttcggcgc cagcgccggt gctttgcggg
     2221 atgtcgccgg tgcggaaggt ccaggccacc tgcaacttgt cgatattgcc cttgttgatc
     2281 tggtccagcg cggcaaagcg gttaccggcg gtggtgttgc cccagtgcgc ccagtccttt
     2341 tgctcggtgc ccggtgcgac cggtgtcacg gtcggttcgc tgctggcctt gaccacgtgg
     2401 gtcggcacga acatgtaggc catggtcgcg acgacaccca cgcccaggat gccggccagg
     2461 ccataggcac cacgacccgc cgtcgcaccc gatgcacgca ccagcgtcgg gtagatcaac
     2521 gcgacgacca ggccgatcac ggcgaacgtc agcacgcgag aaaccagcgg ccagtattcg
     2581 aaaccggcat cccacaccgc ccagatcgcc gtcaggatca gcgccaggcc gtacagccag
     2641 gcaccttgcg gcttacgacg ggcgatcatc accccggaga ccagcatcgc caggcccatc
     2701 aacaggaagt acgcactgcc gcccagcgtg atcaggtaac caccgccacc gaccaggcca
     2761 agcccgatca gtgcgatcag gacacccagc cccgccagca accatttgct gccggcggca
     2821 gccccagaat tattcatgtc ggaaattttc cccatttgtg acaagggcga aatgatgtac
     2881 tacctagtta cttatggcaa attgtcgcac acagaaatgg catgaacggt agtgacctgt
     2941 aacatgctag cccgtccacc tgtgccgctg gagccccctt gtgcctgaca ctcgcccgcc
     3001 cgttctcgac gaaatcgacc gtcagctgat tgccgccttg caaatcaatg cgcgcgaaag
     3061 cgtggccatg ctcgcccgcc aactgggcat cgcccgaacc accgtgacat cgcgtctggc
     3121 acggttggag aaagccaaag tgatcaccgg ttacggcgtg cgcctcggtc agcgggtggt
     3181 agatggtggc ttgcaggcct acgtcgggat taccgtgcag ccgcgctccg gcaaggaagt
     3241 gttgcgtcgt ctgagtgcca tggcccaggt gcagcagtta tgtgcggtca gtggcgaatt
     3301 tgattatgtg gcgtggctgc gcaccgactc gccggagcag ctggatcagc tgctggatca
     3361 gattggcagc gtggatgggg tggagaagac cacgacgtcg atcatcttga gcagcaagat
     3421 tgaccggggg cagccggttt gaacacagtc aatgctggag cgggcctgct cgcgaacgcg
     3481 gtttatcagt gacctttaag ctgactgaca cactgcgttc gcgagcaagc ccgctcccac
     3541 acctgcgcag ttagcatcaa cagttcgtca tattgttcat ttcattagca taacgacgac
     3601 actttgcgtc ttattaacgt gttccaggct ctctagaatg gctgccatct tttcctatac
     3661 tcagacgcgc actccgcgtc cggacgccag caaggtcagc catgaacaag aacaatcgcc
     3721 atcctgcaga cggtaaaaaa ccggtcacca ttttcggccc tgactttcct ttcgccttcg
     3781 acgactggat cgagcacccg gccggcctgg gcagtattcc cgagcaccat catggtgccg
     3841 aagtggcgat cgtcggtgcc ggtatcgccg ggctggtggc cgcctacgaa ctgatgaagc
     3901 ttggcctcaa gcctgtcgtc tacgaggctt cgaagctggg cgggcgcctg cgctcccagg
     3961 cattcaatgg caccgacggc atcgtcgccg agctgggcgg catgcgtttt ccggtgtcgt
     4021 ccaccgcgtt ctatcactac gtcgacaagc tgggcctcga gaccaagccc ttccccaacc
     4081 cgctgacgcc ggcctctggc agcaccgtca tcgacctgga aggcaaaacc cattacgcac
     4141 agaaactggc ggatcttcct gccctgttcc aggaagtggc tgacgcctgg gccgatgccc
     4201 tggaagccgg ctcgcagttc tccgatatcc agcaagcgat ccgcgaccgc gacgtcccgc
     4261 gcctcaagga gctgtggaac accctcgtgc cgctgtggga cgaccgcacc ttctacgatt
     4321 tcgtcgccac ttccaaagcc ttcgccaagt tgtcgttcca tcaccgcgaa gtgttcggcc
     4381 aggtcggctt cggcaccggt ggctgggatt cggacttccc caactcgatg ctggaaatct
     4441 tccgcgtggt gatgaccaac tgcgacgatc accagcacct ggtggtcggc ggcgtggaac
     4501 aagtgccgca gggcatctgg cgccatgttc cggagcgctg tgtgcactgg ccgcagggta
     4561 ccagcctcaa gtcattgcac agcggtgcgc cacgttccgg cgtgaagaaa atcgcccacg
     4621 caccgggcgg tcgcttcgcg gtcaccgaca acaacggcga cacccgcgaa tacgcggcgg
     4681 tgctgaccac ctgccagagc tggctgctga ccacccagat cgaatgcgac gaatccctgt
     4741 tctcgcaaaa gatgtggatg gccctggacc gcacccgcta catgcaatcg tcgaaaacct
     4801 tcgtgatggt cgaccgcccg ttctggaagg acaaggaccc gcaaaccggc tgcgacctga
     4861 tgagcatgac cctcaccgat cgcctgaccc gtggcacgta cctgttcgat aacggcgacg
     4921 acaagcccgg ggtgatttgc ctgtcgtact cgtggatgag cgacgcgttg aaaatgctcc
     4981 cgcacccggt ggaaaaacgc gtgaaactgg cactggatgc gctgaagaag atctacccga
     5041 aggtcgacat cgccgcgcga atcatcggcg atccgatcac cgtgtcctgg gaagccgacc
     5101 cgcatttcct cggtgccttc aaaggcgccc tgcccggcca ctaccgctac aaccagcgca
     5161 tgtacgcgca cttcatgcag gacgacatgc cgcccgaaca gcgcgggatt ttcatcgccg
     5221 gcgacgacgt ttcgtggacg ccggcctggg tcgagggtgc ggtacagacc tcgctcaatg
     5281 cggtgtgggg catcatgaag catttcggcg gcgtcacaca taaagagaac cctggcccgg
     5341 gtgatgtgtt caaagacata ggccctatcg ccctgcccga gtaagaggag ttcccgatgc
     5401 gcgtagccct ttaccaatgc ccacccctgc cgctggatgt ccccggcaac ctgcagcgcc
     5461 tgcaacagct ggcgcaggaa gccaaaggcg ccgacttgct ggtgctgccg gagatgttcc
     5521 tgaccggcta caacattggc gtcgatgccg tcagcgtgct ggcggaagtg cacaacggtg
     5581 agtcggcaca gcaggtcgcg cgcatcgccc gcgccgccgg gattgccatt ttgtacggct
     5641 atcccgaacg caccgaggac gggcagatct acaacgccgt gcagttgatc gacgccgagg
     5701 gcgagcgtgt ctgcaattac cgcaagaccc acctgttcgg tgatcttgac cgctcgatgt
     5761 tcagccccgg caccaaccaa ttccccgtcg ttgaactcaa cggctggaag ctcggtttcc
     5821 tgatctgcta cgacctggag ttcccggaaa acgcccgccg cctggccatc gaaggcgccg
     5881 aactgatcct ggtgccgacg gcgaacatga ttcccttcga tttcatcgcc gatgtcaccg
     5941 ttcgctcccg cgctttcgaa aaccagtgct acgtggccta cgccaactac tgcggccagg
     6001 aaggcgacat ccagtattgc ggccagagca gcattgccgc gccggatggc agccgtatcg
     6061 cccaggccgg ccttgatgaa gccttgattg tcggtgagct gaatcgtcaa ttgatggccg
     6121 actcccgcgg cgccaatcgc tacctcatcg atcgccgtcc cgagctttac ggcgcgctga
     6181 acaagcgcta atccgctagc attggcactt cactgttctg gaagtgccca tgcccgcgct
     6241 gaatccccct cacccccaca ctgaaaccct ggccaacggc ttgcgggtga cgctgcgtca
     6301 cgcccccgat ttgaagcgtt gtgccgccgt gttgcgagtg gctgctggca gccatgacgt
     6361 gcccttggca tggcccgggc tggcgcattt ccttgagcac ctgctgtttc tggggactga
     6421 gcgctttgcg ctggaacaag ggctgatggc gtatgtccag cgccatggcg ggcagttgaa
     6481 tgcgcgcacc catgagcgca ccaccgatta ctttttcgag ttgccacccc aggcgtttgc
     6541 cggtgggctt gagcgtctgt cagacatgct cgcccatcca cgtatgaatc tggaggatca
     6601 gcagcgggaa cgggaagtgt tgcaggcgga atttgtcgcc tggtcacagg atgcgacggc
     6661 ccaacagcaa ttggccctgt tcgacgggct atcgccgcaa catcccctgc gcggcttcca
     6721 cgctggcaac cgcgacagcc tgcccgttga gcaaccggcg tttcagcaag cgttgcaggg
     6781 tttctaccag cagttctatc aggccgggca aatgacgctg agcctggtgg ggcctcaacc
     6841 gctcgaagcc ttgaaagcgt tggcgcagga atttgccgac gccctcccag aaggtgaaaa
     6901 agttcctcgg caagcgcccg tggcgttgat ggacaccctg acaaaaagtt atcaacagcc
     6961 ccacgaacgt cgcctggatc tgttgttcgc attcgaaacg ctgcccgagc gttcccctga
     7021 agcgctggcg ttcttgtgtc actggttgaa caacgcgaag agcggtggat tgctggctga
     7081 gttgcgcagc cgtggctggg ccgacagcct gaaagcggcg ccgttgtatc agttcgccgg
     7141 acaggccttg ctgcacatcg aatgcacact gaacgccgat gcgcagccct ctgcgatcca
     7201 tcacttgctg ctggattggc taggcttttt tgcccggcaa gaatggagcg ggctgcgtga
     7261 cgaatacacc gccctgctcc agcgccagca gcacgtcagt ggcgccttgc agctggcacg
     7321 actggacagt gaacaacacg aagccgggtt atccggacaa ggcgtgaccg ccctcaagga
     7381 tgtcctgcaa caaattggcg ctgtggataa cttcaccggc ccatggcagc tgccggcacc
     7441 caatccgttc ctgcgatccg aagcacccgc ccccaacgcc gggttgattc gtggccagac
     7501 cagcgcccac cgaggcttgc ggacttttgc ccaggatcgc tcgcgcagtc gccgcgaacg
     7561 ttcgccgatg caattcagcc aggccttgcc ggataacacg gccgaaggcg ctgtgtatgt
     7621 tcgttggcgt ctggaatacg caccgggcag ccacgttcag gcgcatctgg acaatggcct
     7681 tcatccgctg cgcgaagatg cacgtcaggc gggcgtggac ttgagttttg gcgcatcagg
     7741 caatgagtgg ctgctgaaaa tgaccggtct gcaagagcct atgcccatca tccttgagca
     7801 tgctctgaaa gaactgacaa aacctggtgg agatttctca caggagcaat ccacgagcgt
     7861 tgcgctgatg ccgattcgac agctgctcaa ggtgctgccc ggtctatgcc tcgaacgcag
     7921 ccccgagtcg caaagcttgc agcaactgtg ggcaagtgcg cgctgggatg gcctggcgac
     7981 gggcctgtcg gctcagactc aagctgccat gggccttgcc ctgagtcgta tcccagggac
     8041 tgcggacaat cagctgacac caccgccatc gatccgctcg cactgcctct ggagccacgt
     8101 cgaaaccggc tccagcgagc atgcattgct gctgttctgc cccactgcaa ccgacgacat
     8161 tgccagcgaa tcggcgtggc gcttactcgc tcacctggcc cagaccccgt tctaccagcg
     8221 cctgcgggtg gagttgcagc tcggctacgc agtgttcagc ggcctgcgcc agttgcacgg
     8281 gcaaaccggg ctgttgttcg gcgtgcagtc accgagcgtg acgccaccgg ttttgctgca
     8341 acacatcgag cagttcctga acggcttgcc agacatgctc cgcgacatgg atgacggcca
     8401 tttcaccgcc ctgcgccaca ccctggccga tcagttcgcc tgcggcgcac tgcccaacgc
     8461 ccaagccgcc gaactgctct ggcacggcaa attggccggc cgctcgtcgg attttctgac
     8521 tcaactgcct gaggcaattc tctcagtgga ccgaccggcg ctcatcgacg ccgcccggcg
     8581 cctgatacaa gccgaaggcg gctggcgctg cctgtccagc gggccttgcc ctggcgcccc
     8641 ttggcaagtg acaaaatgat cattaccgag gctgcaatta actttctcga acatttgcag
     8701 ccaatcaccg tgaaattttg agtaacatag ctgcctaact atctgaacat ctcccgccgg
     8761 aggtggacta tatgtatagg tctctactgt cccatcacct taaggagcgc ccccatgacc
     8821 tggtccaaac ctgcttacac cgacctgcgt atcggctttg aagtcaccat gtacttcgcc
     8881 agccgctaag tttgtcttgt ggtttcaacg cctcggtttg ccgaggcgtt tttattttca
     8941 gcgttgaaat gatggagcac ccatgtttgt ccagattcta ggttccgccg ccggcggcgg
     9001 tttcccccag tggaactgca actgcgtgaa ctgcgcaggt tttcgcgacg gcagcctgcg
     9061 ggccaaggcg cgaacccagt cgtccatcgc gatttccgat gacggcgtga actgggtgct
     9121 gtgcaacacc tccccggaca tccgcgccca gcttcagagc ttcgccccga tgcaaccggg
     9181 ccgcgccctg cgcgataccg ggatcagcgc gatcatcctg atggacagcc agatcgacca
     9241 caccaccggc ctgctcatgc tgcgcgaagg gtgcccgcat caggtctggt gcaccgacat
     9301 ggtccatgag gatttgagca gcggtttccc gctgttcaac atgctgaccc actggaacgg
     9361 cggcctgagc tggaaccgca tcgaactgga ccagagcttc agcatcccgg cctgcccgaa
     9421 cctgcgcttc accccactgc ccttgcgcag cgccgcgccg ccgtattcgc cgcaccgctt
     9481 cgacccgcac ccgggcgaca acatcggcct gatcgtcgaa gacctgaaca ccggcggcaa
     9541 gctgttctac gcaccgggcc tgggcaaggt cgatgcgccg ttgctggaga tcatggccgg
     9601 cagcgattgc ctgctggtgg acggcacgct gtgggacgac gatgaaatgc agcgccgcgg
     9661 cgtcggcacc cgcaccggtc gggagatggg ccacctggcg cagaacggcc ccggcggcat
     9721 gcttgaagtg ctggagcaac tgcccaagca gcgcaaggtg cttatccaca tcaacaacac
     9781 caacccgatt ctcgatgagg attcgccgca gcgcgcggag ctggatcggc ggggtgttga
     9841 agtggcgtat gacggcatga gtattgtgct gtagcggatg gttccttcgc gggcaagccc
     9901 gctcccacag ttgaccgcat tccaatgtgg gagtgggctt gctcgcgaag gcgtccgatc
     9961 agacaccaaa gaatccaccg gccatacccc ggagaaccgc atgaccgaca ccccgatgtc
    10021 ccccgccgaa ttcgaagccg ccctgcgcgc caaaggcgcc tactaccaca tccaccaccc
    10081 ctaccatgtg gcgatgtacg aaggccgggc cacccgcgaa cagatccagg gctgggtcgc
    10141 caaccgcttt tactaccagg tgaacatccc gctcaaggac gccgcgatcc tggccaactg
    10201 tccggaccgc gagatccgtc gcgagtggat tcagcgcctg ctggaccacg acggcgctcc
    10261 cggtgaagac ggcggtatcg aagcctggtt gcgtctgggc caggccgtcg ggctcgaccc
    10321 ggaccagctg cgctcccagg aactggtgct gcccggcgta cgctttgccg tggacgccta
    10381 cgtcaacttc gcccgccgcg ccagttggca ggaagccgcc agcagctcac tgaccgagct
    10441 gttcgcgccg cagatccacc agtcgcgcct ggacagctgg ccgcagcatt acccgtggat
    10501 cgacccggcc ggctacgcgt atttccgcac gcgcctgggc caggcgcgcc gtgatgtcga
    10561 gcacggtctg gcgattacct tgcagcacta cacgacacag gcaggccagg agcgcatgct
    10621 ggaaattctc cagttcaaac tggacattct ttggagcatg ctcgatgcca tgagcatggc
    10681 ctacgaattg aagcgcccgc cctatcacag cgtgaccgaa caacgggtct ggcataaggg
    10741 aattacacta tgagtttcga ccgcagcaag accccgacct ggcggcccgg ctaccgcttc
    10801 cagtacgaac cggcacagaa aggccacgtg ctgctgtacc cggaaggcat gatcaaactc
    10861 aatgaaagcg ccgcgctgat cggcggtttg atcgatggcc agcgcgatgt cgcggcgatc
    10921 atcaccgagc tcgatcagca gttccccggc gtgcccgagc tcggtgacga catcgagcaa
    10981 ttcatggagg tcgcccgtgc tcagcactgg atcgaacttg cctgattcat cggtgcaagt
    11041 gccgcccaaa ccggacatcg gcctgcccct gtggttgctg gccgagttga cctatcgctg
    11101 cccgctgcaa tgcccgtatt gctccaaccc gctggacttc gccgaacaag gcaaggagct
    11161 gagcaccgaa caatggatca aggtgtttcg cgaagcgcgg gaaatgggcg ccgcgcaatt
    11221 gggcttttcc ggtggtgaac cgctggtgcg ccaggacctc gccgagctga ttgccgaggc
    11281 gcgccagctg ggtttctaca ccaacctgat cacctccggc atcggcctga ccgagcagaa
    11341 aatcagcgat ttcaaaaagg ccgggctcga tcacatccag atcagtttcc aggccagcga
    11401 cgaacaggtg aacaacctgc tggccggctc gaaaaaggcc ttcgcgcaga agctggagat
    11461 ggcccgcgcg gtgaaggccc acggctatcc gatggtgctg aacttcgtca cccatcggca
    11521 caacatcgac cggatcgacc gcatcatcga gctgtgcatt gcgcttgagg ctgacttcgt
    11581 cgagctcgcc acctgccagt tctacggctg ggcccagctc aatcgggtcg ggctgttgcc
    11641 gaccaaagag caattggtcc gtgccgagcg catcaccaat gaataccgcg cccggctcga
    11701 agcccaaggg catccgtgca agttgatttt cgtcacgcct gactattatg aagaacgccc
    11761 caaggcctgc atgaatggct ggggcagtat ttttctgacg gtcacgccgg acggcaccgc
    11821 gttgccgtgt cacggtgccc gacagatgcc ggtgcaattt cccaacgtgc gcgaccacag
    11881 catgcagcac atctggtacg actcgttcgg cttcaatcgc tttcgcggtt acgactggat
    11941 gcccgagccg tgtcgctcct gcgacgagaa ggaaaaagac ttcggtggct gtcgctgcca
    12001 ggcgttcatg ctcaccggtg acgcgagcaa cgccgacccg gtgtgcagca agtcgcacca
    12061 tcacggcgtg attctcgccg cccgcgaaga ggccgagcac gcgacccaga ccattggaca
    12121 actggccttt cgcaatgaac gaaattcacg cctcatcgcc aaaagctgaa cccttcagcg
    12181 ccgccagggc cgtcgcggcc ggcatcgact ttgccgaact gcaggtcggc caacagggtt
    12241 tgttctggaa cgaataccgc ccggaggacg ccgcctgccg cctctggcat tggcgcgatg
    12301 gcgtcgcgaa atgtctgacg ccaccgggtt tcagcgtgcg cagtcgggtg tacgaatatg
    12361 gcggtggcgc gttttgcctg acggacgacg gggtggtgtt cgtcaacgaa gcggaccagc
    12421 aactgtatcg ccaatcgttt cagggcgaag cgcccgaggt gctgaccacc ggtgtctgcc
    12481 gttacggcga cttgcagttc gccagcggcc aagtcctggc ggttgaagaa aaccgcgacc
    12541 ggcatcggct ggtggccatc gatctggctg acggcaagcg ccatgtgctg gccgaaggtg
    12601 ccgacttcta cgccgccccg accctcagtc ccgatgtgca acgcctggcg tggatcgagt
    12661 ggagtcgccc ggatcagccg tggaccgcca cccggttgat ggttgccgaa cgccaacgcg
    12721 acggaggctt tggcccgggc cgctgcgtgg ccggcgatga cgctcaagag tccctgcaac
    12781 aaccgcgatt cgataaccga ggccgtttgg gttgcctgac ggatcgcggc ggctactggc
    12841 aaccgtggct ggagtcggcg agcggcctga ccccattgcc gagcgcggcg gccgatcatg
    12901 gccctgcccc ctggcaactc ggcggatgca cctggctgcc gctgaccgac gatcgctacc
    12961 tcgcgagctg gaccgaaggc ggtttcggcc ggttgggttt gtggtcaggt gccgttgaag
    13021 agtttgctgg cgactacacc cgtttccgaa gcctcgccgt ggatgctcag tgcatttact
    13081 gcatcgccgc ctcgccggtc agttcctcgg cagtgatcgc catcgaccgc cagacccggc
    13141 aggtcaaggt gcttgccggc ggtatcgcac ccttgcccgc cgagcaagtc agtcgcccgc
    13201 aaaccctgtg ctatccaagc ggcgcggggc aggcgcacgg cttcttctac ccggccatga
    13261 cgggcgaggc aaaaccgcca ctggtggtgt ttatccatgg tggaccgacg tccgcctgct
    13321 acccgatgct cgacccccgc atccagtact gggcccaacg cggtttcgcc gtcgccgacc
    13381 tcaactaccg tggcagcagc ggttacggtc gagcgtaccg gcaggcgctg catttgagtt
    13441 ggggcgaggt ggatgtcgaa gacgcttgcg cggtggtcag ccatctcgcc gaacgcggat
    13501 tgattgatgg cgacaacgca ttcattcgcg gcggcagtgc cggtggctac accacactgt
    13561 gtgcgctggc cttccgcagc gtattccggg ccggcgccag cctgtatggg gtcagcgacc
    13621 ccgtcgccct gggccgggcg acgcacaaat tcgagggcga ctacctggat tggctgatcg
    13681 gtgatcccgt gcaagacgcc gagcgctatg ccgcgcggac gccgctgctg cacgcgggca
    13741 acatccgcgt gccggtgatc ttctttcagg gcgaactgga cgccgtggtc gttccgcagc
    13801 agacccggga catggtcgag gcgctgcaca acaacggcat tgcggtccaa gcccattact
    13861 acgcggacga acgccatggc tttcgcaagg ccggcaacca ggcccatgca ctggaacagg
    13921 agtggttgtt ttatcggcgg gtgatggatc agctggactg agcagaattt gcggcgccgc
    13981 cattcgcgag caagcacgct cccacagagt ctgtggtgta cacaaaacct gtgagagcgg
    14041 gcttgcccgc gaaagctatc taccaggcgg ggccagactc aacgcttggc gatgatgtac
    14101 accgcatgca cgatccccgg aatgtaaccg cacaacgtca acagaatgtt cagccagaac
    14161 gccccgccaa accctacttg cagaaacaca cccaacggcg gcaacagaat ggcgatgatg
    14221 atgcgaataa aatccatggg gtcagctcct gattgaagtc ggctcatgcg agccctacat
    14281 gcaatcgacc tgtgccgttg gtcagggttc agcccttttc ctcaggccag tatttcaagc
    14341 ccgtgtttct ggacgatgct cagcaacttc aacgccatgc cactggggtg cttgtccccg
    14401 gcctcccatt gcttgaccgt ggacgcgctg gtgttcaagt aacgtgcaaa caccggctga
    14461 ctgacattgt tgcgctcacg cagcgctttg atctgctctg ctggaattgc gtccgggacg
    14521 gtcgcaagac aggactcatc gaactcgcgc atggtcgcct ttgttattgc accgatggca
    14581 aacaaggcac tggcagactc gtgaatcgac tccgctattt cacttttgaa ttttttactc
    14641 ataacgtatc tccacaaact ccctcatatc cagcaaacgc tggattccca tctcagacag
    14701 ccctccggat gtcttggcta attcgcgcaa gtcggccaag tgcctcggag tgatattgct
    14761 ctgatccttc ttggcataga gaaactgata cacccagtaa cggcctccct ttgccaaaag
    14821 aatcgaccga tgacggttgg cattcaaacg tttcttccaa acgtcaccac ccaggttatc
    14881 agcctggcca ttcagcattt cggcgaacgc ctcccgaagc tcgtcatcac cgatccatgc
    14941 cttcgcggcc tgcattgcaa aacgttttgt cttgaacagc cttggtgaca ttggcatccc
    15001 ttccctgaaa acataccacc cagtggtatg gaactcaaag ccaacgcccc aacaaagttg
    15061 ttacgccagc atcggcactc cttgccgacg ccctgtaaaa agccactgat cccgtcatgg
    15121 ctcaagccga aattgccttg tgcaaaaccc agccacaaaa aaacgcccca cgccaaaaga
    15181 atcaggcgtg gggcgtgcgt tataccgcga gacggttcgg gaattcaggc agggcgcgtc
    15241 cggtcagacg gcgattcctt tgcggcactg caattgcgcc gtgcgcacac gggagaaggc
    15301 ccgggccagg cgtagcagca tttcgtcgat gttggccttg ctgacggtca atgccggggt
    15361 aaagcgcagg acgtcgggtt gcggggcgtc gagcagcaag ccttcgtaca gcgccgcctt
    15421 gaccaccgcc tccgcgcaat cgtcggacag ggtcaggccc cagagcagtc cttggccacg
    15481 caattcgccg tggccataac gatgggataa acgttgcagg ccttcgcgca ggtgctgggc
    15541 ggtttccccg atatggtcga gaaacccttt gtcctgcacg ctgtcgagca cggccaggcc
    15601 cgccatggtc atcagcgcat tgccatgatg ggtgccgctc atttcgccgc tgtcgaagca
    15661 acaggccttg ccccgcgcca gcaaggccgc cagcggtacg ccaccgccca ggcctttgcc
    15721 gagcacaacg atatcggccc gtacgccgta ggattgttcg gcgagcacgg tgccgcagcg
    15781 accgataccg gtttgcactt cgtcgaggat cagcaggatg ccaagctccc gacacaggcg
    15841 ctcgacccct ctgaggtaat gggccgtggc cggaatcacc ccggctgcgt tctggatcgg
    15901 ctccagcatg atcgccaccg tccgctcatc cacggcggcg tgcaacgctg ggaggtcgtt
    15961 gaacggcaca gggctgaaac ccggaagttg cggctcgaat cggttgatca gcgtcgaact
    16021 gtctgacgcc gacatcgtcc ccagactacg gccatggcag ccgttgctgg caacgatgat
    16081 ccgcgaagcg ccgccccggt gctgctgacc ccatttgcgc gccagtttga tcgccgcttc
    16141 acaggcttcg ctgcccgtgt tgagcagata cgcctggtcg ctaccggtgc tcaggcacag
    16201 gcgttcggcg aggttgagca tgccgcggtt atgcaggccg aagccgggat tgatcagcga
    16261 ccgggcctgc gccgttatcg cgttgaccag ggccttgggg ctgtggccga ggctattggc
    16321 cccgccgccc tgggaaaaat ccagatacgc gcgatcttcg ctgtcccaca accacgaacc
    16381 ctggccgcgg acgaacacct gctgcggccg ctcgacactc ggcatcagac actcgctcgc
    16441 caggatgtca tccccggacg caaaggatgc gtcagccacc agatcatcga ggctcggtga
    16501 atgacggcgc aggttgaaca gattcatggg ttcaaccctc gcttgaggtt ttttgcgtta
    16561 cctatgtaaa caccatcgaa gcaatcgcta ttcatcgcgt tctgtggccc tgtaagcctt
    16621 atgaatgcgg ttagactagg cgcagacacg gcgttgagcc atttcgattt ccgagcattt
    16681 tcgataagta ttacttatgg atttcaagca actgcgttat ttcgtcgcgg tctacgaaga
    16741 aggccatgtg ggacgcgccg ccgaacggct gtcgatctcg caaccggcgc tgtcccagca
    16801 gatccgccac ctcgagcaga ctctcgatgt cagcctgttc gagcgcagca gtaaacgcct
    16861 gttgccgacg ctggcggccc acacgctgta caaccacgcc ctgcccttgc tcgacggctt
    16921 gcaacgggcc cgcgaagcgc tgggtaattt caagggccag gcgttgcgca cactggccat
    16981 cggtgtcctg cagaccgtgc acaccagcct ggtgccgcaa atgctcgaac gggtgcgcaa
    17041 ggcccaaccg catctggtgg tgcagatcta tgaattgacg ggcctggaga tcgagcgacg
    17101 cctgctcaat ggttcgctgg acatcggcat cagctatttg ccaccccggc aaccgggact
    17161 gcacggcgtg atgctgtacg aagatgaact gacccttgtc atcccggcgg agcatccgtt
    17221 gcgcgaattc aagaaagtgt ccatgaagca ggctgccgag ctgccgatgc tgctactggg
    17281 cgaggagttc caggtgcggc agatctggca ggcgcagctg gcgaacctgg gacggcggcc
    17341 gcaggtgcag gcggaactga acaacatggc tgggattctc gacagcctgc cgcacacgcg
    17401 cctggccacc gtgctgcccg ggcgctcaca aaaggcccat ggcaataagg atttgctgtg
    17461 gaagccgctg agcgaaccac gggtgccact caaagtcgga ttggtgtgtc gggatgtgca
    17521 acggcaacag gcctcgctgg cgttgttgcg caccttgctg gaagaagtga tgaatcagcc
    17581 ggatgagcgc ttgaacagca cgtcggaacg ggatggcctg agctgaatac tttttcgcgg
    17641 gcataagaaa accccgccga agcggggctt tgcagactgt ttccctgaca tccatttcac
    17701 tccgccatcc tggcagaatc ctacgtgtcc gtgttgttgc tttgcgcttc ctgcgctacg
    17761 tccatgtgaa gtagattagc cgtggatcca attcgctact atgggagaac agcagcacgt
    17821 catgtaagag aatgcttaca tgaggttaca ttctcagaac tgcgccgcgt ccagcagaaa
    17881 cagcgactca ctgcccgctt tcaccgacgc actcaacgag tggatgcgcg gcaacaggcg
    17941 ggcgaaatag aaccgcgccg tgcccagttt actcgcgtag aaatcgtcct gcgcttcctt
    18001 gcccaaggcc gccttggcca tcaatgccca catgtaggcg taagcggtgt agccgaaggc
    18061 ttgcaggtac tccaccgaag cggcgccgat ttcattcggg ttgtttttcg cccggtcgag
    18121 caaccaggcg gtcagctcat ccagcgtggt caccgcatcg ttcaacggct tggtgaactc
    18181 cgccaggtca gcgctggcgg tggccgtgaa gtgacgaatc tcgtcggcga acaggttgta
    18241 gaacgccccg ccgctgccga cgatcttgcg cccgaccagg tccagcgcct gaatgccgtt
    18301 ggtgccttcg tagatctggg taatgcgcac gtcgcgcacc agctgctcct ggccccattc
    18361 acggatgtaa ccgtggccgc cgaacacctg ctggccgtgc accgtggttt ccaggccgag
    18421 gtcggtgagg aacgccttgg ccaccggggt cagcagcgcc accagatctt ccgcgcgctt
    18481 gcgcgtcgtg gcgtcttcgc tgaacttggc ggtgtccagt tgcatggcca catacgtcga
    18541 gaaggcacga ccgccttcgt tcgaggcttt catggtcagc agcatgcgac gcacgtccgg
    18601 gtggacgatg atcgggtccg ccaccttgtc cttgttctgc gcgccggtcg gcgaacggct
    18661 ttgcagacga tcacgggcgt actcgacggc gttctgatag gagcgttcac cgctggccag
    18721 gccctggatg ccgacaccca ggcgctcgta gttcatcatg gtgaacatcg ccgccaggcc
    18781 cttgttcggc tcgccaacca gataacccac ggcttcatcg aagttcatca cgcaggtcgc
    18841 ggacgcctgg atgcccatct tgtgttcgat cgaaccgcaa ttggccgggt tgcgcgcgcc
    18901 caggctgcca tcggcattga ccatgaactt gggcaccagg aacagcgaga tgcccttggg
    18961 tcccgccggt gcgtccggca acttggccag caccaggtga ataatgtttt cggtcaggtc
    19021 gtgctcacca ccggtgatga agatcttggt gccgctgacc ttgtaggaac cgtcggcctg
    19081 gggttcggcc ttggtgcgga tgatccccag gtcggtgccg gcatgcggct cggtcaggca
    19141 catggaaccg gcccagacgc cggcgtacat gttcggcagg tacgcggcct tcagctcgtc
    19201 gctggcgtgg gcgttgatcg acaggcaggc gcccgcggtc agcatcgggt acaggccgaa
    19261 cgacaggctc gcggagttga ccatttcttc gacctgggcc gataccgcct tgggcatgcc
    19321 catgccgccg taggccggat cgccaccgac accgacccaa ccgccttcag cgtaggtctg
    19381 gtaagcctgg gggaagccgg ctggggtggt gacggcaccg tccgcccagt ggcaaccttc
    19441 ttcgtcagcc gcgcggctca ggggtgcgat gcttttgctg gtgaccttgc cagcctcttc
    19501 gagaatggct tcgaccgttt cggcatcgac ggtatcggcc agcgccggca gctcggccca
    19561 gagtttggcg acctcgaaga cttcattgag gacgaagcgc atatcgcgca ggggcgcttt
    19621 gtagtcagcc atggcaaacc tcgcaagatc taatacaggt gattcacagg aatggtgctt
    19681 tggatgtgtc ggagtgtaac ccaacaactt ttgcgacaca tagggtcagc acatgaccaa
    19741 tttgtaattt ttagtcatcg cttgatacac agggaatcgt aagaattgta ggagctgccg
    19801 aaggctgcga tcttttgatc ttgccattaa aagatcgcag cctcgttaca ctcgacagct
    19861 cctacagggg gcagtgtcag agggcgaata gctccgccgg cagctgcatc aggcaatcac
    19921 tccccgcctc gatccccgcc cggtgcgcct cggtgcgcgg caacaggcgc ttgaagtaaa
    19981 actcgctggt cgccagtttc gcccggcaga aatcggcatc gccgctgccc tcttccagcc
    20041 gagcctgcgc caccaacgcc atgcgcaacc acaaataacc cagaatgatg taaccgctgt
    20101 acatcaggta atccaccgag gcggccccga cctcatccgg attgttcatc gcggccatgc
    20161 cgacccgggt cgtcaactca ccccattgcc gattcaggtc attgagctgg gccacatgga
    20221 cggccaactg tggatgcgcg gcgttggcca ggcagaactt gtggacgatt ctggtaaagc
    20281 cccgcagcag cttgccctgg ctgccgagga cttttcgccc gagcaagtcc agcgcctgaa
    20341 taccgttggt gccctcatag atcggcgcga tacggcaatc gcgaaccagt tgctccatgc
    20401 cccattcacg aatgaaacca tggccgccga acacctgcat gccgtggttg gtcacctcca
    20461 ggccggtttc ggtcatgaag gctttgcaga tcggcgtgag gaacgccaac aggtcttcgg
    20521 cgtcctggcg cgccgccgcg tccgcgctca ggtgcgcggt gtccagcaac tgcgcggtga
    20581 aataggtcag cgcgcggttg ccttcgttga aggctttcat cgtcagcaac atccggcgga
    20641 cgtcgggatg aacgatgatc gggtcggcgg ctttttccgg cgctttcggg ccggtcagcg
    20701 cgcgcatctg caagcgctca ttggcgtact tgatcgcccc ctggaaactc gcttcgccca
    20761 gacacaaacc ctgcatgcca gtacccagcc gcgcatggtt catcatggtg aacatgcagt
    20821 tcaggccctt gttggcttca ccgatcagga aaccctgggc gccgtcgaag ttcagcacgc
    20881 aggtggccga ggccttgatg cccattttgt gttcgatgga cccgcacgac acgccattgc
    20941 gcgccccggc ttcgcccgcg gcatcgggca ggaacttggg cacgatgaac agtgaaatgc
    21001 ccttggtccc ggcgggcgca tccggcagtt tcgccaacac caggtgaatg atgttgtcgc
    21061 tcatgtcgtg ctcaccggca gagatgaaaa tcttgctgcc ggagattgca taactgccat
    21121 cggcctgggg cacggcgcgg gtcttgatga tgcccaggtc ggtgccgcaa tgggcttcgg
    21181 tcaggcacat ggtgccggtc cattggccgg cggtgagttt gctcaggtag gtctgtttct
    21241 gcgcgtcggt gccgtgggcg tggatcgccg acatggcgcc atgggtcagg ccagggtaca
    21301 tgccccacga ggtgttgctg gacgccacca tttcgctgat gaccagcccc agggagctgg
    21361 gcaaaccctg gccaccgtag gccggatcgg ccgccaaacc atgccagccg ccttccacgt
    21421 attgtgcgaa cgcctgcttg aagccggccg gcgtcgtcac cacgccgttg tcgaaatggc
    21481 agccctcttc gtcgccgctg cggttgaggg gcgacagcac gttctcgcag aatttcgcgc
    21541 cttcctcgag gatcgcattg atcatgtccg ggctggcgtc gttggccccc agtgccgcgt
    21601 agtggctgtg aaagtcgaag acgtggtcga tcagaaagcg catgtcgcgc aggggagctt
    21661 tgtactcggg catggtcgtt tctccggcgg caggttttct tcaacctact gctggcaacc
    21721 acgcctcaca atcacagtcc agacgctgaa tgcgccatca tcactcaacc gcagcggcat
    21781 ccatgcgcac ggcgccacgg cgggtctgcc cgaaggccac cacgcagttt cgcccggcgc
    21841 ccttggcgct gtagagcgcc tggtcagcgg acttgagcac ttcttcgggg gtgcgctgct
    21901 cgacccgttc ggcgacgccg atactgaccg tgaccgacac gctcgacgcg ctggaaccgg
    21961 agcgacgctg acggccctga ctgtcatctt gcggacggtt gtcctgattg cgcaggtgaa
    22021 tgttgtaggt ggcgatggac tcgcgaatca cttccaggtg cggcatgcac tcttcgaggg
    22081 tcttgcctgc aaacaccagg gcaaattcct cgccgccgta gcgataggcc ttgccgccac
    22141 cgccgatttt cgccagcttg ctggccacc
//
