LOCUS       NZ_CABVIY010000009     23036 bp    DNA     linear   CON 07-NOV-2023
DEFINITION  Pseudomonas fluorescens isolate PS918, whole genome shotgun
            sequence.
ACCESSION   NZ_CABVIY010000009
VERSION     NZ_CABVIY010000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Pseudomonas fluorescens
  ORGANISM  Pseudomonas fluorescens
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
REFERENCE   1
  AUTHORS   Chandra,G. and Truman W,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2019) JOHN INNES CENTRE, NORWICH, UK., Molecular
            Microbiology, Norwich Research Park, Norwich NR4 7UH, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/07/2023 08:57:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,059
            CDSs (total)                      :: 5,986
            Genes (coding)                    :: 5,920
            CDSs (with protein)               :: 5,920
            Genes (RNA)                       :: 73
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 7 of 66
            Pseudo Genes (incomplete)         :: 63 of 66
            Pseudo Genes (internal stop)      :: 6 of 66
            Pseudo Genes (multiple problems)  :: 8 of 66
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:35:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 212814
            Orig. end                         :: 235850
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CABVIY010000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23036
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23036
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23036
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13036](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13036
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(1114..1845)
                     /locus_tag="F8N66_RS29105"
                     /old_locus_tag="PS918_05561"
     CDS             complement(1114..1845)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008149150.1"
                     /locus_tag="F8N66_RS29105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05561"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_150773373.1"
                     /transl_table=11
                     /translation="MERWKELQLEQISATSEIESAYRTSLQFAKNIGFKFFAFSTTCPT
                     KSENFHTSRFNNYPDAWNAEYAKNKLGTIDPIVAHCNQSTLPILWSEELFRNAPRLWES
                     LEQQGLQHGWSQAVHDDQSGFCSIVSMARSHRQISAWELYENLGFSLFIGHHLHHLLMQ
                     TLPKVPAKSSSPHLSPREIDVLKLAADGKTAYESARILNLSARTVNFHIQEVIRKFGVN
                     NKVSAVIAAAKAGLLSSTLMR"
     CDS             complement(2046..2129)
                     /gene="allorf_214860_214943"
                     /locus_tag="allorf_214860_214943"
                     /protein_id="allorf_214860_214943"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MFLEQMLFICKQQKFGQSIYEARQKFD"
     CDS_motif       complement(2103..2129)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MFLEQMLFI"
                     /locus_tag="allorf_214860_214943_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(2046..2102)
                     /prepeptide="core"
                     /locus_tag="allorf_214860_214943_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.50"
                     /molecular_weight="2186.4"
                     /monoisotopic_mass="2185.1"
                     /core_sequence="CKQQKFGQSIYEARQKFD"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MFLEQMLFI"
                     /leader_location="[2102:2129](-)"
     gene            2199..2975
                     /locus_tag="F8N66_RS29110"
                     /old_locus_tag="PS918_05562"
     CDS             2199..2975
                     /EC_number="1.18.1.2"
                     /GO_function="GO:0004324 - ferredoxin-NADP+ reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_253305.1"
                     /locus_tag="F8N66_RS29110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05562"
                     /product="ferredoxin--NADP reductase"
                     /protein_id="WP_150773374.1"
                     /transl_table=11
                     /translation="MTASEEKFTRQTLLDVQPLTPNLFTLRATRDPGFRFRAGQFARLG
                     VTKADGSTVWRAYSMVSSPFDDFLEFFSIVVPGGEFTSELSRLGVGDTLLVDRQAFGYL
                     TLDRFVDGRDLWLLSTGTGLAPFLSILQDFEVWEKFERIILVYSVRETRELAYQELIAG
                     LAQREYLAEFAHKLQLINTVTREEHPGALNGRITTLIENGELERAAGVALTPEHSRVML
                     CGNPQMIDDTRKLLKQRDMHLSLSRRPGQVAVENFW"
     gene            complement(3021..3434)
                     /gene="mscL"
                     /locus_tag="F8N66_RS29115"
                     /old_locus_tag="PS918_05563"
     CDS             complement(3021..3434)
                     /GO_function="GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /GO_process="GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="mscL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008010503.1"
                     /locus_tag="F8N66_RS29115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05563"
                     /product="large-conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="WP_150773375.1"
                     /transl_table=11
                     /translation="MGVISEFKAFAVKGNVVDMAVGIIIGAAFGKIVTSFVGDVVMPPI
                     GLLIGGVDFSDLAITLKAASGDAPAVVLAYGKFIQSLIDFVIVAFAIFMGVKAINRLKR
                     EEAVAPTLPPVPTKEEELLGEIRDLLKAQNNRP"
     misc_feature    complement(3544..3559)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.59"
                     /tool="antismash"
     misc_feature    3633..3646
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 21.07"
                     /tool="antismash"
     CDS             3654..3764
                     /gene="allorf_216468_216578"
                     /locus_tag="allorf_216468_216578"
                     /protein_id="allorf_216468_216578"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MMISMRHKVSKGGYFHAVVEANDSKFKRGVEILCGG"
     CDS_motif       3654..3692
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MMISMRHKVSKGG"
                     /locus_tag="allorf_216468_216578_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3693..3764
                     /prepeptide="core"
                     /locus_tag="allorf_216468_216578_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.00"
                     /molecular_weight="2521.8"
                     /monoisotopic_mass="2520.3"
                     /core_sequence="YFHAVVEANDSKFKRGVEILCGG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MMISMRHKVSKGG"
                     /leader_location="[3653:3692](+)"
     misc_feature    3711..3729
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.91"
                     /tool="antismash"
     misc_feature    complement(3714..3729)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.24"
                     /tool="antismash"
     misc_feature    3955..3968
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.61"
                     /tool="antismash"
     gene            4061..5428
                     /gene="radA"
                     /locus_tag="F8N66_RS29120"
                     /old_locus_tag="PS918_05564"
     CDS             4061..5428
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="radA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_253299.1"
                     /locus_tag="F8N66_RS29120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05564"
                     /product="DNA repair protein RadA"
                     /protein_id="WP_150773376.1"
                     /transl_table=11
                     /translation="MAKAKRMYGCTECGSTFPKWAGQCGECGAWNTLTETMVESGGAAA
                     PTGRTGWAGQQAQIKTLAEVSVEEIPRFSTASSELDRVLGGGLVDGSVVLIGGDPGIGK
                     STILLQTLCNLAKSMPALYVTGEESQQQVAMRARRLGLPQDQLRVMTETCIETIIATAR
                     QEKPKVMVIDSIQTIFTEQLQSAPGGVSQVRESAALLVRYAKQSGTAIFLVGHVTKEGA
                     LAGPRVLEHMVDTVLYFEGESDGRLRLLRAVKNRFGAVNELGVFGMTDKGLKEVSNPSA
                     IFLTRAQEEVPGSVVMATWEGTRPMLVEVQALVDDSHLANPRRVTLGLDQNRLAMLLAV
                     LHRHGGIPTHDQDVFLNVVGGVKVLETASDLALMAAVMSSLRNRPLPHDLLVFGEVGLS
                     GEVRPVPSGQERLKEAAKHGFKRAIVPKGNAPKEAPAGLQIIAVTRLEQALDALFE"
     gene            complement(5524..5892)
                     /locus_tag="F8N66_RS29125"
                     /old_locus_tag="PS918_05565"
     CDS             complement(5524..5892)
                     /GO_function="GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008004293.1"
                     /locus_tag="F8N66_RS29125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05565"
                     /product="PilZ domain-containing protein"
                     /protein_id="WP_150773377.1"
                     /transl_table=11
                     /translation="MSDHPADRRRFKRIAFDAKTELSQGAFIWPVKLIDLSLKGLLIER
                     PEPWLGNPRQDFFVDIHLSEDIDIEMDVRLSHEDHGQLGFVCRHISLESIERLRRLIEF
                     NLGDPQELERELGALIDI"
     misc_feature    complement(5882..5897)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.32"
                     /tool="antismash"
     gene            6051..8117
                     /locus_tag="F8N66_RS29130"
                     /old_locus_tag="PS918_05566"
     CDS             6051..8117
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1185: carbon
                     starvation protein A"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_253296.1"
                     /locus_tag="F8N66_RS29130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05566"
                     /product="carbon starvation CstA family protein"
                     /protein_id="WP_150773378.1"
                     /transl_table=11
                     /translation="MKNNNSLLRHIPWLVLAIVGACALGVVALRRGEAINALWIVVAAV
                     AIYLVAYRYYSLFIANNVMQLDPRRATPAVLNNDGLDYVPTNKHILFGHHFAAIAGAGP
                     LVGPVLAAQMGYLPGTLWLIAGVVLAGAVQDFMVLFMSTRRNGRSLGDMVREEMGRIPG
                     TIALFGCFLIMIIILAVLALIVVKALAESPWGIFTVMATIPIAMFMGIYMRYIRPGRIG
                     EISVVGVLLLLGSIWLGGQIAADPVWAKAFTFNGVQITWMLIGYGFVAASLPVWLILAP
                     RDYLSTFLKIGTIVALAIGILITTPELKMPALTQFIDGTGPVWKGGLFPFLFITIACGA
                     VSGFHALISSGTTPKLLDNEVNARYIGYGGMLMESFVAIMAMVAASVIEPGVYFAMNSP
                     AAVVGGDVVAVAQTVSSWGFAITPEALQAVAHDIGETTILARAGGAPTLAVGIAQILHS
                     VLPGENTMAFWYHFAILFEALFILTAVDAGTRAGRFMLQDLLGSFVPALKRTESWTANL
                     IATAGCVAMWGWLLYQGVIDPLGGINTLWPLFGISNQMLAGIALMLGTVVLIKMKRQRY
                     IWVTLLPAVWLLICTTTAGFIKLFDANPAIGFLSLAKKYSDALANGQILAPAKDVTQMQ
                     HVIFNAYTNATLTALFLFVVFSILFYALKVGIASWGKKERTDKESPFQALPDA"
     gene            8132..8329
                     /locus_tag="F8N66_RS29135"
                     /old_locus_tag="PS918_05567"
     CDS             8132..8329
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1211: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_253295.1"
                     /locus_tag="F8N66_RS29135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05567"
                     /product="YbdD/YjiX family protein"
                     /protein_id="WP_077046022.1"
                     /transl_table=11
                     /translation="MFNDLSRLGKYLGQAARLMVGMPDYDNYVEHMQNKHPDKPVMSYE
                     AFFRERQEARYGGKGGPKCC"
     gene            8493..9464
                     /gene="yjiA"
                     /locus_tag="F8N66_RS29140"
                     /old_locus_tag="PS918_05568"
     CDS             8493..9464
                     /EC_number="3.6.5.-"
                     /codon_start=1
                     /gene="yjiA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1178: cobalamin synthesis protein/P47K family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007970879.1"
                     /locus_tag="F8N66_RS29140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05568"
                     /product="GTPase"
                     /protein_id="WP_150773379.1"
                     /transl_table=11
                     /translation="MSSPIPVTILSGFLGAGKTTLLRHLLKTEHGLKIAVIENEFSDAG
                     IDTQLLGDEPVQVMTLSNGCVCCTIHTDLTKALYLLLERLDSGEIAFDRLVIECTGLAD
                     PAPVAQTFFIDEELRERYILDGIITLVDAAHAETHLTQTIAQAQIGFADRLLVSKRDLV
                     DEPTFSALSDRLTRINRRAPIRVVDHGKIDLAELLDVRGFNLNADLGGGVSLRPVTQAP
                     SIDRISSLVLRTDKPLDIDKLSEFMNELLEDHGKQLLRYKGVLNILGEPRRMVFQGVLK
                     LYGFDWDTEWAEDEPRESIIVFIADDLPEDKIREGFTRVAAE"
     gene            9759..9920
                     /locus_tag="F8N66_RS31570"
                     /old_locus_tag="PS918_05569"
     CDS             9759..9920
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F8N66_RS31570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PS918_05569"
                     /product="hypothetical protein"
                     /protein_id="WP_191623064.1"
                     /transl_table=11
                     /translation="MQELILDLSGEFGAEFQAYVNSGNADVAAEIGCDTTVGCPTVACT
                     VLQPCCLP"
     CDS_motif       9759..9800
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MQELILDLSGEFGA"
                     /locus_tag="F8N66_RS31570_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9801..9920
                     /prepeptide="core"
                     /locus_tag="F8N66_RS31570_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.00"
                     /molecular_weight="3871.4"
                     /monoisotopic_mass="3868.8"
                     /core_sequence="EFQAYVNSGNADVAAEIGCDTTVGCPTVACTVLQPCCLP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MQELILDLSGEFGA"
                     /leader_location="[9758:9800](+)"
     misc_feature    9975..9989
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.57"
                     /tool="antismash"
     gene            10001..13036
                     /gene="lanM"
                     /locus_tag="F8N66_RS29145"
                     /old_locus_tag="PS918_05570"
     CDS             10001..13036
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018081 - peptide cross-linking via
                     lanthionine or 3-methyl-lanthionine [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="F8N66_RS29145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05570"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_150773380.1"
                     /sec_met_domain="DUF4135 (E-value: 3.5e-69, bitscore:
                     228.0, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.6e-48, bitscore:
                     158.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPMAEKYDALSKMIDLLHKDDKAIQYCFGIDRQALLEEYRDTL
                     LLGNATADRASEADQAKIRLIVSLSQGDDAEQVMFGRFCACWYGFLRHVFERDPKYETL
                     CEWIDVETFLPSIRSHLTSQVKQLALKSLVHQLNSRIADGADLDLELFDREVAGVGLPQ
                     FLASYPVLTRMLIERIEDTVAYLYKILCYFKLDICQLESTFGLCERQIGSISMGLGDAH
                     ANGETVCCVKVGTVELIFKPRSNREVLFYNALLEKMRTQTGNSYFAIHAPLMVSSDNHC
                     WIEKIENVPCETESELLLFYKRLGAQVAVIHALNGKDFHYENIIAHGSSPVMIDLECLF
                     TSAMVDLRVDEPHGRALFKIIRLNSQSVFTTGFVSNAAGSDNDQSGLSRQQRFVVTRPL
                     LVPEQGFYRLKPQEVDTRPLMQHLPVFEGEVRSVIAYEEAFLYGFKVGYDDVMNHREAV
                     LELLAEHAQGLKTRVLIKSTQRYADFIGMMTHPHFTQCQFKHELLLATLWADLGDRLNK
                     YDIPRHEIHDLKKANFPCFTQALLSDHLLDAHGQTVALLPIELPFESCRNKLETLSPKD
                     KAFQVHILQACVFPLATEFLPLNRSHHLEAVPDFGRVQYLEGAMRIAAIIEKNRIDGEL
                     GDVGWTCIETHPRTGRNFLTHMGNSLFNGMGGLAIFYLSLFRVGGVTRHRDEAERILYS
                     MSQSQGQFSRKLEVSAYLGLTSYLYVLVNYELMTGRQTYQANVEELLLKLADFPREDDE
                     FDFILGWCGALTVLVNLYQLGKRETLRPLIEKFSNAIQSALTLEKGVLRLKTTGKPLLT
                     GFSHGISGVMQAVGKAWEITKDPQLAELISTWLQAENHHTVDGYWLDLREDAKSASSIK
                     WCHGDGGILIARHGLVQSMGRALSAETRAVLEQDAERCERHLWEQGLGSGYSLCHGDFG
                     NLMCLLKRYRETSNESGIAKVNRALSQVAHNFFNEDFLDEYKFPDLSMMLGITGAGQAL
                     LQAVNADLPDVLALEFAKPATH"
     CDS             13046..13111
                     /gene="allorf_225860_225925"
                     /locus_tag="allorf_225860_225925"
                     /protein_id="allorf_225860_225925"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSRPLASAHYGTERGPCRVPA"
     CDS_motif       13046..13078
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSRPLASAHYG"
                     /locus_tag="allorf_225860_225925_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13079..13111
                     /prepeptide="core"
                     /locus_tag="allorf_225860_225925_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.20"
                     /molecular_weight="1067.2"
                     /monoisotopic_mass="1066.5"
                     /core_sequence="TERGPCRVPA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSRPLASAHYG"
                     /leader_location="[13045:13078](+)"
     gene            complement(13175..14428)
                     /gene="glyA"
                     /locus_tag="F8N66_RS29150"
                     /old_locus_tag="PS918_05571"
     CDS             complement(13175..14428)
                     /EC_number="2.1.2.1"
                     /GO_function="GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0070905 - serine binding [Evidence IEA]"
                     /GO_process="GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (83-371). E-value:
                     1.1e-11. Score: 36.4. Matches aSDomain:
                     nrpspksdomains_F8N66_RS29150_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="glyA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003340745.1"
                     /locus_tag="F8N66_RS29150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05571"
                     /product="serine hydroxymethyltransferase"
                     /protein_id="WP_020798669.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.5e-11, bitscore:
                     36.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSRDLTIAKYDADLFAAMEQEAQRQEEHIELIASENYTSPAVME
                     AQGSVLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHAGSQANSA
                     VYLALLSAGDTILGMSLAHGGHLTHGASVSSSGKLYNAIQYGIDANGLIDYDEVERLAV
                     EHKPKMIVAGFSAYSQILDFPRFREIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADV
                     VTTTTHKTLRGPRGGLILARANADIEKKLNSAVFPGAQGGPLEHVIAAKAICFKEALQP
                     EFKAYQQQVVKNAQAMASVFIERGFDVVSGGTENHLFLLSLIKQEISGKDADAALGKAF
                     ITVNKNSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELAGWICDILADLNNEAVID
                     AVREKVKAICKKLPVYGA"
     aSDomain        complement(13316..14179)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F8N66_RS29150_Aminotran_1_2.1"
                     /evalue="1.10E-11"
                     /label="F8N66_RS29150_Aminotran_1_2.1"
                     /locus_tag="F8N66_RS29150"
                     /protein_end="371"
                     /protein_start="83"
                     /score="36.4"
                     /tool="antismash"
                     /translation="ELFGADYANVQPHAGSQANSAVYLALLSAGDTILGMSLAHGGHLT
                     HGASVSSSGKLYNAIQYGIDANGLIDYDEVERLAVEHKPKMIVAGFSAYSQILDFPRFR
                     EIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGGLILARANAD
                     IEKKLNSAVFPGAQGGPLEHVIAAKAICFKEALQPEFKAYQQQVVKNAQAMASVFIERG
                     FDVVSGGTENHLFLLSLIKQEISGKDADAALGKAFITVNKNSVPNDPRSPFVTSGLRFG
                     TPAVTTR"
     misc_feature    14449..14465
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.93"
                     /tool="antismash"
     misc_feature    complement(14483..14499)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.23"
                     /tool="antismash"
     gene            complement(14668..18516)
                     /locus_tag="F8N66_RS29155"
                     /old_locus_tag="PS918_05572"
     CDS             complement(14668..18516)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_195670259.1"
                     /locus_tag="F8N66_RS29155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05572"
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="WP_150773381.1"
                     /transl_table=11
                     /translation="MSSVLPPLTTSAPSTANGSPLRGTLKSALASLVLLLLALLFWQLL
                     DQLRENQKTQRQYTIDYTADLAAQVSLNMALNAQIALNLLPIVEQPQSIEEQQELLRKL
                     QKSLPDLTSLALLSPSGTILTDSATNSEDADYLSELVRRSRAQPHYFSNAIDGSVVHLL
                     LHQASGSTRGYWALRFNPRFFSSLTQLNGTDGRPQWLVENRFNHQIISRDEALPLVNPG
                     MLTQDDVSNSVLTVPLSGSDWQLRGLFDRQRVLEELLPAFIGKCLLCLAFSMLPFIVLL
                     NMRRRQRQLHEGRRRYQEIFEGTGVALCVLDMSGLKSAFDKARLQSQEQLQGWLEDREQ
                     RLQLLQALRITEVNQVALQLLNVSTSGQAWDLLIDGNPLDGSAIGNQVLEAVLNQQQQL
                     ELEIKLQDATGRDQHLWLVLRLPQNAEGFKAVILSITDITSRKLIELSLLEREGFWSDV
                     VRTVPDHLYVQDVISQRMIFSNHHLGQTLGYNRTELQHMGEYFWEILLHPDDADYYHRS
                     RQNQRQGGYSQLMQCQLRFRHRDGEWRRFDIREQALARDKHDQVTRIIGVAKDVTEQIE
                     ASESLRDSEQRYRMLAESISDVIISTDNRMSLNYVSPSVQAVLGYDAEWIFQNGWQSTI
                     ANPQQLAGIYSLMERVSKALDQPEQLALLRTQVQTQMFLFDCLRADGRKIPIELRLVLV
                     WDEHDTFEGVLGVGRDISQQRRAEKDLRMAATVFEHSTSAILITDPAGYIVQANEAFSR
                     VSGYAVEQVLDQLPNMLTVDQEQEAHLHYVLKQLNQNSTWEGEVWLKRRNGEHYPAWVG
                     ITAVLDDEGDLASYVCFFSDISERKASEQRIHRLAYYDALTHLPNRTLFQDRLHTALQA
                     AERQKSWVVLMFLDLDRFKPINDSLGHAAGDRMLKDMATRLLGCVDDDDTVARMGGDEF
                     TLLLQPRANREIALNRAIHVAEQILASLVKPFVLEGREFFVTASIGIALSPQDGNELSQ
                     LMKNADTAMYHAKERGKNNFQFYQADMNASALERLELESDLRHALEQNEFVLYYQPQFS
                     GDGKRLTGAEALLRWRHPRRGLVPPGDFIPVLEELGLVVDVGDWVISEACRQLKTWHQA
                     KVRVPKVSVNISARQFSDGQLGTRIATILKDTGLPPACLELELTESILMREVSEAMQIL
                     DGLKNLGLSIAVDDFGTGYSSLNYLKQFPIDVLKIDRTFVDGLPSGEQDAQIARAIIAM
                     AHSLNLAVIAEGVETQEQLDFLREHGCDEVQGYLFGRPMPADRFEVQFSDDALFVFD"
     misc_feature    complement(18714..18727)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 23.03"
                     /tool="antismash"
     gene            18802..20466
                     /gene="ettA"
                     /locus_tag="F8N66_RS29160"
                     /old_locus_tag="PS918_05573"
     CDS             18802..20466
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0045900 - negative regulation of
                     translational elongation [Evidence IEA]"
                     /codon_start=1
                     /gene="ettA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_253285.1"
                     /locus_tag="F8N66_RS29160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05573"
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="WP_150773382.1"
                     /transl_table=11
                     /translation="MAQYVFTMHRLGKVVPPKREILKNISLSFFPGAKIGVLGLNGSGK
                     STLLKIMAGVDTEFEGEARPMPELNIGYLPQEPILDPTKTVREVVEEAVSVIKNAQARL
                     DEVYAAYADEDADFDKLAAEQAKLEAILQAGDGHNLERQLEVAADALRLPAWDAKVEFL
                     SGGEKRRVALCRLLLSAPDMLLLDEPTNHLDADSVAWLEHFLHDFPGTVVAITHDRYFL
                     DNVAGWILELDRGAGIPYEGNYSGWLEAKSDRLAAESKQQSAHEKAMKEELEWVRKGAK
                     ARQSKSKARLQRFEEMQSQEFQKRSETNEIYIPAGPRLGDKVIEFKNVTKGYGDRVLID
                     NLSFSMPKGAIVGVIGGNGAGKSTLFRMLMGKETPDSGSIEVGETVQLACVDQSREDLD
                     GSKTVFQQISDGSDQIRIGNYEIPSRTYVGRFNFKGGDQQKFVKDLSGGERGRLHLALT
                     LKEGGNVLLLDEPSNDLDVETLRSLEEALLDFPGAAIVISHDRWFLDRVATHILAYEDD
                     SQAVFFEGNYTEYEADRKKRLGEAAAQPHRVRHKKLA"
     CDS             20478..20552
                     /gene="allorf_233292_233366"
                     /locus_tag="allorf_233292_233366"
                     /protein_id="allorf_233292_233366"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MHEKAEPSGSVFFCVSFSASAVGP"
     CDS_motif       20478..20507
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MHEKAEPSGS"
                     /locus_tag="allorf_233292_233366_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       20508..20552
                     /prepeptide="core"
                     /locus_tag="allorf_233292_233366_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="1363.6"
                     /monoisotopic_mass="1362.7"
                     /core_sequence="VFFCVSFSASAVGP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MHEKAEPSGS"
                     /leader_location="[20477:20507](+)"
                     /alternative_weights="1381.6"
                     /alternative_weights="1399.6"
     misc_feature    20803..20818
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.48"
                     /tool="antismash"
     gene            20831..22168
                     /gene="gdhA"
                     /locus_tag="F8N66_RS29165"
                     /old_locus_tag="PS918_05574"
     CDS             20831..22168
                     /EC_number="1.4.1.4"
                     /GO_function="GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gdhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_253278.1"
                     /locus_tag="F8N66_RS29165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05574"
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="WP_150773383.1"
                     /transl_table=11
                     /translation="MIESVESFLARLKKRDPDQPEFHQAVEEVLRSLWPFLEANPHYLT
                     SGILERICEPERAIVFRVSWVDDHGKVQVNRGFRIQMNSAIGPYKGGLRFHPSVNLGVL
                     KFLAFEQTFKNSLTSLPMGGGKGGSDFDPKGKSDAEVMRFCQAFMSELYRHIGADVDVP
                     AGDIGVGAREIGFLFGQYKRLGNQFTSVLTGKGPSYGGSLIRPEATGFGCVYFAEEMLK
                     RRGLTVEGKRVAISGSGNVAQYAARKVMDLGGKVISLSDSEGTLYCESGLTEEQWQAVL
                     ELKNVQRGRISELAGRFGLEFLAGQHPWELSCDIALPCATQNELDADAARTLLRNGCVC
                     VAEGANMPTTLEAVDLFIDAGILFAPGKASNAGGVAVSGLEMSQNAMRLLWTGGEVDSK
                     LHAIMQSIHHACVHYGEENGQVNYVKGANIAGFVKVADAMLAQGVV"
     gene            complement(22165..22659)
                     /locus_tag="F8N66_RS29170"
                     /old_locus_tag="PS918_05575"
     CDS             complement(22165..22659)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228387.1"
                     /locus_tag="F8N66_RS29170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_05575"
                     /product="GreA/GreB family elongation factor"
                     /protein_id="WP_150773384.1"
                     /transl_table=11
                     /translation="MSRAFVNEDNAAAQADQPVERQVSAQPNYVTGAGLDLLQEKVAEL
                     QALHAQQSARGDQADKQLLANLERDLRYFHQRLQSAQVVPAATSTSKVQIGSRVTYVDE
                     QGTEHRVQLVGEDQAAAAKGLINWGSPLGRALLGAQLGDEVLWQRPAGDQLIGIVRIEP
                     V"
ORIGIN
        1 gccgacgacc tgttgctggt gaaacggtgg gttgcacagc accacgtcca gcgactgggg
       61 ctcctggcca gccaggccat caccggcacg cacgatgaca tcgcgctcac ccagtgcggc
      121 gcgccagttt tcggcggccg actgcacggc catgaacgat tcatccacca gcgtgtaatg
      181 ggcgtcaggg ttttgcaggg cactggcgat ggccagcaca ccgttgccgc atccgaggtc
      241 ggccacccgt gccgtgccaa gactcttcgg cagatgcggc aaaaacgccc gtgtgccgat
      301 gtccaggcct tcgcggcaga agacgttggc gtggttgagc agttcgatgg caggtgcgtc
      361 gagacgatag cgggtcggat agggcgacgt gaccggcgct ttgtcttcag ccgtggcgat
      421 caacaaccgc gccttcttga ccgccagcga cgcctgcacc ggcccgatat agcgttcgag
      481 cagatccccc gcggcacgtg gcagatgctt gatcatcgcc cccgcgacga cttgagcgcc
      541 gggtgccaat tggccttgca ggcgaatcag ttgttcttcc agcaacgcca gagtctttgg
      601 cacgcgtatc aggacccggt caaacggtcc cgccggtgtt tcgctggctg caatggccgg
      661 caccgaatcg aatgccaggc cattgcgggc caggttcttc tccagcccct ggaacgccag
      721 gaatgaatcg ccgctgctgg tcacgtcgac ctttccggcc aggctcgcgg ccaaggcgcc
      781 gaaactgtcg ttaaggacca gcactcgtgt atcgatcgag gtttgctgct cggccagatg
      841 gttgagcagg tattcgtcag ccgcgtcaaa agcttgcagc ggttcgtttt gctgttcagg
      901 ctggcggatc aggtcgaggc tggcgaaagg tgtttcgagc aaaggcatgg ggcggggctc
      961 tgggtaatca tcggggtatc ccgcgcccag ggggcgtcgt ggcgggcggg gccgtccgag
     1021 tgcactgcgt cgtggagggt tcacacgtca gcactcagga ggaaccgtgg atggtacttt
     1081 ttttcgtgtc ggattactcg caggtttttc caatcagcgc atcaaagtgc tgctgagcaa
     1141 acccgccttc gcggcggcaa tgacagccga gaccttgttg ttgactccga acttccggat
     1201 gacttcctgg atatggaaat tgaccgtgcg ggcgctgagg ttgaggatcc gggcgctttc
     1261 ataagccgtc ttgccatccg ccgccagctt caacacgtcg atctcccgtg gcgacaaatg
     1321 cggcgatgac gatttggctg gcactttggg cagtgtctgc atcaacagat ggtgtaaatg
     1381 atgcccgatg aagagggaga aaccgagatt ctcatacaac tcccacgcac tgatttggcg
     1441 atggctcctg gccatactca cgatgctgca gaatccgctt tggtcatcat gaacggcttg
     1501 cgaccagcca tgctgtaagc cttgttgttc gagtgactcc catagcctgg gagcattgcg
     1561 aaacagttcc tcactccaaa gtattggcag tgtggattga ttgcaatgcg ccactattgg
     1621 atcgatggtg cccaatttgt ttttcgcata ttcggcgttc caggcatcgg gataattgtt
     1681 gaaccgcgac gtatgaaaat tctccgactt cgtagggcaa gttgttgaaa aggcgaaaaa
     1741 tttaaagccg atgtttttgg cgaactgcag tgatgttcgg taggcacttt caatttcgct
     1801 cgtcgcagat atttgttcga gttgtaactc cttccacctt tccatcatgc aactccctct
     1861 gtgtatataa cgcgatcaac ctaacttgga tctgggatca cgatgagttt ggagtgtagg
     1921 atgaatccta caatgacgct gagaatattt tgaatttatg cccggctgaa agttactgat
     1981 ctggttctat agataggcgg tggcaggtta ttgaatgtca ctgttaatat taaagatctc
     2041 atgggttaat caaacttctg acgtgcttca tatatagatt ggccgaattt ttgttgtttg
     2101 caaatgaaga gcatttgctc caaaaacact acaaatcgcc ggtgtttatg gcgcccgctt
     2161 tgcgagacac tgcggctatc cgatgattgg agcccctcat gaccgccagt gaagagaaat
     2221 ttacccgtca gaccctgctc gacgttcagc ccctgacccc gaacctgttc accctgcgcg
     2281 ccacccggga tccgggcttc cgttttcgag cggggcaatt tgcccggcta ggcgtcacca
     2341 aggcggacgg cagcacggta tggcgtgcct attccatggt ttcatcgcct tttgacgact
     2401 ttctcgaatt cttttccatt gttgtgccgg gcggtgagtt caccagtgag ctgagccggc
     2461 tgggcgttgg cgatacattg ctggtcgacc gccaggcctt cggttacctg acactcgatc
     2521 gttttgtcga tgggcgggat ctgtggttgt tgtccacggg cactggcctg gcgccgtttt
     2581 tgtcgatcct ccaggacttc gaggtatggg agaaattcga gcgaatcatc ctggtctaca
     2641 gcgttcgcga aacccgggag ctggcctatc aggagttgat cgctggcctg gcgcagcgcg
     2701 aatacctggc ggaattcgcg cacaagttgc aactcatcaa caccgtgacg cgtgaagagc
     2761 atcctggcgc actcaatgga cgaattacca cgctgatcga aaatggcgaa ctagagcgcg
     2821 cggccggcgt ggcactgacg ccggagcact cgcgggtcat gctgtgcggc aacccgcaga
     2881 tgatcgatga cacccgtaag ttgctcaagc agcgtgacat gcacttgagc ctcagccgcc
     2941 gaccggggca ggtggcggtg gaaaatttct ggtaaagaaa cggcgcctgc aaggcgccgt
     3001 cttatttgcc atcagtgtgt tcaaggtcga ttgttctggg ccttgagcag gtcgcggatc
     3061 tcccccagca actcttcttc cttggtggga accggcggca gggtaggggc cacggcctcc
     3121 tcgcgcttca ggcggttgat ggccttgacg cccatgaaga ttgcgaaggc aacgatcacg
     3181 aagtcgatca ggctctggat gaatttaccg taggcaagca ccaccgccgg ggcatcaccg
     3241 ctggccgctt tgagcgtaat ggccaggtca ctgaagtcca ccccaccgat cagcaggcca
     3301 atgggaggca tgaccacgtc accgacaaac gaggtgacga tcttgccgaa cgcggcgccg
     3361 atgatgatac cgacggccat gtcgaccaca ttgcccttga cggcgaaggc cttgaactca
     3421 cttatcacgc ccataggtta ttccttgtta cagatgaggt tggtgaacgc agtgtaattc
     3481 agcaaggtgc attctgcttg aaacaactgc ttgcagggct tgcctgcaat cgaccggttg
     3541 ggcgttgaaa agtttaaaca aaagctgatt tcgtcctcgt atcttccttt tttggcacac
     3601 gcctgccagg tcgttttcac tctctatcca actggccagg atctaaggct cgattgatga
     3661 tttctatgcg ccacaaagtt tcgaagggtg gatattttca tgctgttgta gaagcgaatg
     3721 attctaagtt taaacgtgga gtggaaattc tatgcggtgg ttaataccct tgcgggtcct
     3781 ggggttgtta gctattgagt tgtacggtgg attttttatt tatagggttc gtacaggttt
     3841 catatttgat tgatggcggt tttataggtt gtcgtcacgg attggttata cagcgggtaa
     3901 cttgatgtaa tgtactaact gtttaatgag ctataggatt agtggttcgt ttcgttgcgc
     3961 gcgatcaaat aaattccttg cctatcgaca tccgtagggc ctcagctcgc gctgattacg
     4021 cgcggctgag ctatcatcgc ggtttttgcc gggagttcag atggccaagg ccaagcgcat
     4081 gtacggctgc accgagtgcg gctcaacctt ccccaagtgg gccggccagt gcggtgaatg
     4141 cggggcctgg aacacactga ccgaaaccat ggtggaaagc ggcggggccg cggcgcccac
     4201 cgggcgtacc ggatgggccg ggcaacaggc gcagatcaag accctggccg aagtcagcgt
     4261 cgaagaaatc ccgcgctttt ccacggcatc cagcgagctg gatcgggtac tgggtggcgg
     4321 tctcgtcgac ggctcggtcg tgctgatcgg cggcgatccc ggcatcggca aatcgaccat
     4381 ccttttgcaa accctgtgca acctggccaa gagcatgccg gccctgtacg tcacgggcga
     4441 agagtcccag caacaagtgg ccatgcgcgc ccgacgcctg ggtttgccac aggatcaact
     4501 gcgggtcatg accgagacct gcattgaaac catcatcgcc acggcacggc aggaaaagcc
     4561 caaggtcatg gtgatcgact cgatccagac gatcttcacg gaacaactgc aatcggcgcc
     4621 gggtggcgtc tcacaggtgc gcgaaagcgc ggcgttgctg gtgcgctatg ccaaacagag
     4681 cgggacggcg atcttcctgg tcggccacgt gaccaaggaa ggcgcactcg ccggtcctcg
     4741 cgtgctggag cacatggtcg atacggtgct gtattttgag ggcgagtccg acgggcgttt
     4801 gcgcctgttg cgggcggtga agaaccgttt cggcgcggtc aacgagctag gcgtgttcgg
     4861 catgaccgac aagggcctga aagaagtctc caatccgtcg gccattttcc tgacccgcgc
     4921 tcaggaagaa gtcccgggca gtgtggtcat ggcgacatgg gaagggaccc ggccgatgct
     4981 ggtggaagta caggcgctgg tggatgacag ccatctggcc aacccgcgtc gagtcacgct
     5041 ggggctggac cagaatcgcc tggcaatgtt gctggcggtg ttgcaccgtc acggcggtat
     5101 tccgacccac gatcaggacg tgtttctcaa cgtggtcggt ggtgtgaagg tcctggagac
     5161 agcctctgac ctggcgttga tggcggcggt gatgtccagc ttgcgcaacc ggccgctgcc
     5221 ccatgatctg ctggtattcg gtgaagtcgg cctgtccggc gaagtgcgcc cggtgcccag
     5281 cggtcaggaa cgactgaaag aagcggccaa gcatggcttc aagcgggcca tcgtgcccaa
     5341 gggcaatgca ccgaaagaag cgccggcggg gttgcagatc attgccgtca cacgtctgga
     5401 acaggccttg gacgccttgt tcgaataaac acaggtccct gtagcaggct gcgatctttt
     5461 gactttgcta ttgaacaaca agatcaaaag atcgcagcct gcggcagctc ctacaaggtg
     5521 tgctcagatg tctatcaggg cacccagctc ccgctccagt tcctgcggat ctcccagatt
     5581 gaattcaatc aaccgccgca gccgttcaat ggactccagg ctgatatgcc ggcagacaaa
     5641 tccgagctgg ccgtggtctt catggcttag ccgcacatcc atctcgatgt cgatgtcctc
     5701 gctcagatga atatcgacga aaaaatcctg ccgcgggttg cccagccaag gttcaggccg
     5761 ctcgatcagc agccccttga gcgatagatc gatcagcttc accggccaga tgaacgctcc
     5821 ctggctcagc tcggttttgg catcgaacgc aatacgtttg aagcggcggc gatcggcggg
     5881 gtggtcgctc atggcgcaat cctctggatg ttcgctgact atagacccgc attgtcagaa
     5941 cctgccagcc agcacaagcg tctagaccaa cgttgggtat ggtctttgcc gtcagtagcg
     6001 ctaaactcgg tgtggctgtc tttcttgtcc actctggctg gaatcataaa atgaaaaata
     6061 ataatagcct gctacgccac ataccctggc tggtgctggc aatcgtggga gcgtgcgccc
     6121 tgggcgtagt ggcattgcgc cgaggcgagg cgatcaacgc cttatggatt gtggtcgccg
     6181 ccgtggccat ttatctggtc gcgtatcgtt actacagtct gttcatcgct aacaatgtga
     6241 tgcaactcga cccgcgacgg gccacccccg ccgtgctcaa caacgacggt ctggactacg
     6301 ttccaaccaa caaacacatc cttttcggcc accacttcgc ggccatcgcc ggcgcggggc
     6361 cgctggtcgg tccggtcctg gcggcgcaga tgggctacct gcccggcacg ctgtggctga
     6421 tcgccggtgt ggtgctggcc ggtgcagtgc aggacttcat ggtcctgttc atgtccaccc
     6481 gccgcaacgg ccgttcgcta ggcgatatgg tccgtgagga aatgggccgc atccccggca
     6541 ccatcgcgct gtttggctgc ttcctgatca tgatcatcat cctcgcggtt ctggcgctga
     6601 tcgtggtcaa ggccctggcc gaaagcccgt ggggcatctt cacagtgatg gcgaccatcc
     6661 cgatcgcgat gttcatgggc atttacatgc gctacatccg cccgggccgc atcggtgaaa
     6721 tctcggtagt cggcgtgttg ctgctgttgg gttcgatctg gctgggcggg caaatcgccg
     6781 ctgatccggt gtgggccaag gcctttacct tcaatggcgt gcaaatcacc tggatgttga
     6841 tcggctacgg tttcgtcgcc gcttcgctgc cggtgtggct gatcctggca ccccgtgact
     6901 acctgtcgac ctttctgaaa atcggcacca tcgttgccct ggcgatcggc atcctgatca
     6961 ccacgcccga gctgaaaatg ccggcgctga cccagttcat cgacggcacc ggtccggtgt
     7021 ggaagggcgg cctgttcccg ttcctgttca tcaccatcgc ctgtggcgcc gtgtcgggtt
     7081 tccatgcact gatttcctcc ggcaccacgc ccaagctgct tgataacgag gtcaacgccc
     7141 gttacatcgg ctacggcggc atgctgatgg aatcctttgt ggcgatcatg gccatggtcg
     7201 ccgcttcggt gatcgagcct ggcgtgtact tcgccatgaa cagtccggcg gccgtggtcg
     7261 gcggtgatgt ggtggcagta gcacaaaccg tcagcagctg gggctttgca atcaccccgg
     7321 aagcgctgca agccgtggcg catgacatcg gtgaaaccac catcctggcc cgtgccggtg
     7381 gtgcgccgac cctggcggtg gggatcgcgc agatcctgca cagtgtgctg ccaggtgaaa
     7441 acaccatggc gttctggtac cacttcgcga tcctgttcga agcgctgttc atcctgaccg
     7501 ccgtcgacgc gggcacccgt gccgggcgtt tcatgctgca ggacttgctc ggttccttcg
     7561 tgccagcgct caagcgcacg gaatcctgga ccgccaacct gattgccacc gccggttgcg
     7621 tggccatgtg gggctggctg ctgtatcagg gcgtgatcga tccgctgggt ggcatcaaca
     7681 ccttgtggcc actgttcggc atctccaacc agatgctggc cggtatcgcg ctgatgctcg
     7741 gcaccgtcgt gctgatcaaa atgaaacgcc agcgctacat ctgggtgacc ttgctgccag
     7801 cggtatggct gctgatctgc accaccactg ccggcttcat caagctgttc gacgccaacc
     7861 cggcgatcgg cttcctgtcg ctggccaaaa aatacagcga tgccctggcc aatggtcaga
     7921 tcctcgcccc ggccaaggac gtcacgcaga tgcagcacgt gatcttcaat gcctacacca
     7981 atgccacgct gaccgcgctg ttcctgttcg tggtgttcag catcctgttc tacgcgctca
     8041 aggtcggcat cgcttcctgg ggcaaaaaag aacgtacgga taaagaatcg cccttccagg
     8101 cgctgccgga tgcgtgatcg aggactgcaa catgttcaat gacttgagtc gcctcggtaa
     8161 atacctcggt caggccgcgc gcctgatggt cggcatgccc gactacgaca attacgtcga
     8221 gcatatgcaa aacaagcacc cggacaaacc ggtgatgagc tatgaggcgt tcttccggga
     8281 acgtcaggag gcccgttacg gtggcaaggg cgggccgaag tgttgttgat ccaacaacca
     8341 ggttgacgca ataccctgtg ggagcgggat tgctcgcgaa agcggtgtgt cattcaacat
     8401 tcatgtcgac tgatacgacg tcttcgcgag caagcccgct cccacatttg ttttgtgttt
     8461 ttctttgaat tcaatgcaac aggagagtca gcgtgtcctc ccccatcccg gtcaccatcc
     8521 tcagcggctt cctcggcgca ggcaaaacca cgctgttgcg ccacctgctc aaaaccgagc
     8581 acggcctgaa aatcgccgtg atcgaaaacg aattcagtga cgccggcatc gacacccaac
     8641 tgttgggtga tgagccggtg caagtgatga cgctgtccaa cggctgcgtc tgttgcacca
     8701 tccacaccga cctgaccaaa gcgctgtatc tgctgctcga acgcctggac agcggtgaaa
     8761 tcgccttcga ccgactggtg attgaatgca ccggcctggc cgatccggca ccggtggcgc
     8821 aaaccttctt catcgacgaa gagctgcgcg agcgctacat cctcgacggc atcatcaccc
     8881 tggtggacgc cgcgcacgcc gagactcacc tgacccagac catcgcccag gcacagatcg
     8941 gtttcgccga ccgtttgctg gtgagcaagc gcgacctggt ggatgagccg acgttcagcg
     9001 ccctgagcga tcgcctgacc cgtatcaacc gtcgcgcgcc gattcgtgtg gtcgaccatg
     9061 gcaagatcga tctggccgaa ctgctcgatg tgcgtggttt caatctcaat gccgacctgg
     9121 gcggcggcgt gagtttgcgc ccggtcaccc aggcaccttc catcgaccgt atctccagcc
     9181 tggtgctgcg caccgacaag ccgctggata tcgacaaact cagcgaattc atgaacgaac
     9241 tgctggaaga ccatggcaag caattgctgc gctacaaggg tgtattgaac atcctgggcg
     9301 agccacggcg catggtgttt caaggcgttc tcaagttgta tggattcgat tgggacactg
     9361 aatgggcgga agatgaaccg cgtgaaagca tcatcgtatt tattgccgat gatttaccgg
     9421 aggataaaat ccgagagggg tttacacgag tggcagcaga gtagggttga atagtcgata
     9481 cgatacggtg agttgataag tgccgtagga gcgaggtttt cattcgaaag cgatttgtct
     9541 ggccgtcgag atagctcgct cctggcgcat cgcaagtaat ctttacagtc tgtttcagcc
     9601 ggttggcatt taaaaagtac ttcggattgg ctgctgatag gtagcgtcgt cgtttacatt
     9661 ttgttctgtt tgaagtggag tgaagttttc cggtcaatga tagttttgtt gttcgccagt
     9721 caaggcgatt aataaacttt ctttcaggag aaacacccat gcaagagctg attttggatc
     9781 tgtccggtga atttggtgcg gagttccagg cctatgtgaa ttccggtaac gccgatgtcg
     9841 ctgcggaaat tggttgtgat accacggttg gctgtccgac cgtggcctgc accgtacttc
     9901 aaccctgctg cctcccataa taagacaagg cgggctctgg cccgccttgt ttttacgagc
     9961 tcccgatatt ggcaaacttt ctgaaagtcg agtgaatgtt atgagtgcac caatggcgga
    10021 aaagtatgat gccttgagca aaatgattga tctgctgcac aaagatgaca aggctattca
    10081 gtattgtttt gggattgatc gtcaggcgct gctggaagag tatcgtgaca ctttattgct
    10141 cggtaatgct acagccgatc gggcaagtga ggcggatcag gcgaaaataa gattaattgt
    10201 ttcattgtct cagggtgacg atgctgagca agttatgttt ggcagatttt gtgcctgttg
    10261 gtatggtttt ctaaggcatg tgtttgaacg tgatccgaag tatgaaaccc tatgtgagtg
    10321 gattgatgta gaaacgtttt tgccgagtat tcgttctcac ttgacttcac aggtcaaaca
    10381 acttgcattg aaatccttgg ttcatcagct caacagccgg attgctgacg gtgctgatct
    10441 ggatctggaa ctatttgatc gggaagtggc tggcgtgggg ctgccacagt tcctggcatc
    10501 atatccggta ctgacacgca tgctgattga gcggatcgaa gatacggtcg cgtatctgta
    10561 caagatccta tgttatttca agttggatat ttgccagctt gaaagcactt ttggattatg
    10621 cgaaaggcag atcggttcaa tttccatggg cttgggcgat gctcatgcca acggcgaaac
    10681 tgtctgttgc gtgaaagtcg gcactgtgga gctgatattt aaaccaagaa gcaatcgtga
    10741 agtactattt tacaatgcgt tgctcgaaaa gatgcggacg cagacgggaa atagctattt
    10801 cgccatacat gcacccctta tggtttcttc ggataatcac tgctggattg aaaaaatcga
    10861 aaacgtgccc tgcgaaacag aaagcgagtt gttgcttttc tataagcgcc tgggggcaca
    10921 ggttgcagtg atccatgcat taaatggcaa agacttccac tatgaaaata tcattgccca
    10981 tgggagcagt ccggtaatga tcgatcttga atgcctgttc acttcggcca tggttgatct
    11041 aagggttgat gaaccgcatg ggcgggcgct tttcaaaatc atcaggctca atagccagtc
    11101 ggtgtttaca acaggttttg tttccaatgc agcaggctcg gacaatgacc aaagtggttt
    11161 gagccgccaa cagaggtttg tcgtcacgag gccactgtta gtacctgagc agggcttcta
    11221 tcgcttgaaa ccacaggaag tcgacactcg cccgttgatg caacacctcc ctgttttcga
    11281 aggtgaggtg cgttcggtca ttgcttacga agaggctttt ttatacggtt tcaaagttgg
    11341 ttacgatgac gtaatgaacc atcgagaggc ggtacttgaa ttgctggccg agcatgcaca
    11401 agggttgaag acccgtgtgc tgatcaaaag tacccaacgc tatgccgatt tcatcggaat
    11461 gatgactcat ccacatttca ctcagtgtca gttcaaacat gaattgttac tcgcaacctt
    11521 gtgggctgat ctcggtgaca ggctaaataa atacgatatc ccgagacacg aaatccacga
    11581 tctcaagaag gctaattttc catgttttac tcaagccttg ctgtctgacc atttgctcga
    11641 cgctcatggt cagaccgttg cgcttttacc gattgagctt ccttttgaga gttgccgaaa
    11701 caagctggaa acactatccc caaaggacaa ggcgttccag gttcatatat tgcaggcgtg
    11761 tgtgtttccc ctcgccactg aatttttgcc actcaatcga agtcaccact tggaagccgt
    11821 ccccgacttt ggtcgcgtgc agtatctcga aggcgctatg cgcattgccg caatcattga
    11881 aaaaaaccgc atcgacggcg agctgggcga tgtcggctgg acgtgcattg agacgcatcc
    11941 ccgaaccggc cgcaattttc taacgcacat gggcaatagc ttgttcaacg gaatgggagg
    12001 actggctatt ttctacctga gtctgttccg ggttggcggg gtgacgcgtc accgggatga
    12061 ggcagagcga atcctgtatt cgatgagtca atcccaaggg caattttcac gcaagctgga
    12121 ggtcagtgcg tatctcggcc tgacttccta cctgtacgtg ttggtcaatt atgagctgat
    12181 gactggccgt cagacctatc aggcgaacgt cgaagagctg ttgttgaaac tggcggattt
    12241 tccacgcgaa gacgatgaat tcgatttcat tctgggctgg tgtggcgccc tgaccgttct
    12301 ggtgaatctg taccagctcg gaaagcgtga gacattgcgc cccctgatcg aaaaattctc
    12361 aaacgccatt caatcggctc tgacgctgga gaagggagtg ctgcggctca agacaacggg
    12421 gaaaccgctg ttaaccggtt tttctcatgg catttcggga gttatgcagg cagttggcaa
    12481 ggcttgggag attacgaaag atccacagct cgccgagctg atttcaacgt ggttgcaagc
    12541 agaaaaccat cacacggtcg atggttactg gcttgacctt cgggaagacg ccaagtctgc
    12601 gtcatctatt aaatggtgcc atggtgatgg cggtattctc attgcccggc atgggctggt
    12661 tcaatcgatg gggagggcgt tgagcgccga aaccagagcg gtactcgagc aggatgccga
    12721 gcgctgtgag cgccatctct gggagcaggg gctcgggtct ggttacagct tgtgccatgg
    12781 tgattttggc aatctgatgt gcctgcttaa acgctatcgc gagacaagca acgaatcggg
    12841 cattgcgaag gtcaatcgcg cgctctctca agtggcccat aatttcttca atgaagattt
    12901 tctggatgag tacaagtttc ccgacctgag catgatgcta ggcatcacgg gtgctggtca
    12961 ggccctgctg caggccgtga atgcagactt gccggatgta ttggcattgg agtttgccaa
    13021 acctgctact cactgagcgg caattttgtc gcgcccgttg gcgtcagcac actacggtac
    13081 tgagcgtggc ccttgtcggg tgccggcatg acccgctcat aaaaaaaccg gccatctctg
    13141 gccggttttt cattgctgcg gtttagcggg ctgattaggc gccgtacacc ggcagcttct
    13201 tgcagatagc cttgaccttc tcgcgaacgg cgtcgatcac cgcttcgttg ttcaggtcgg
    13261 ccaggatgtc gcagatccag ccggccagtt ccttgcactc ggcttccttg aagccgcgag
    13321 tggtcaccgc cggggtgccg aagcgcaggc cggaggtgac gaacggggag cgtgggtcgt
    13381 ttggcacgga gttcttgttc acggtgatga acgctttgcc cagagcggcg tcggcgtctt
    13441 taccggagat ttcctgcttg atcagcgaca gcaggaagag gtggttttca gtaccgccgg
    13501 aaaccacgtc gaaaccgcgc tcgatgaata cgctggccat ggcctgggcg tttttcacca
    13561 cttgttgctg gtaggccttg aactcaggct gcagcgcttc cttgaagcag atggccttgg
    13621 cggcgatcac gtgctccagc gggccaccct gggcgccagg gaatacggcg gagttcagct
    13681 ttttctcgat gtcggcgttg gcgcgagcca ggatcaggcc gccacgtgga ccgcgcaggg
    13741 tcttgtgcgt ggtggtggtc acgacgtcag cgaatggaac cgggttcggg tagacgccag
    13801 cggcgaccag accggccacg tgggccatgt cgacgaacag gtaggcgcca actttgtcag
    13861 cgatttcgcg gaagcgcggg aagtccagga tctgcgagta ggcagagaaa ccggccacga
    13921 tcatcttcgg cttgtgctcg accgccaggc gctcgacttc gtcgtagtcg atcaggccgt
    13981 tggcgtcgat cccgtactgg atggcgttgt acagcttgcc ggaggacgaa acgctggcgc
    14041 cgtgggtcag gtgaccgccg tgggccaggc tcatgcccag gatggtgtca ccggccgaca
    14101 gcagggccag atagacggcg ctgttggctt gcgaaccggc gtgcggctga acgttggcgt
    14161 aatcggcgcc gaacagttct tttgcacggt cgatggccag ttgctcaacg atgtcgacgt
    14221 actcgcaacc gccgtagtag cgcttgcccg ggtagccttc ggcgtacttg ttggtcaata
    14281 ccgagccttg agcttccatc accgcagggc tggtgtagtt ttccgaagcg atcagctcaa
    14341 tgtgctcttc ctggcgctga gcttcttgct ccatggcggc aaagagatcg gcgtcgtact
    14401 tggcaatagt caaatcacgg ctgaacatgg cggtcctcaa ggatcggggg cagaaaaggg
    14461 gggcattcta ccccaacggg ttttggaagg catatgaaag gacatcatgt cgcagacaag
    14521 tggtgttcat gcggggatta gcggtgatcg tgccggcctc ttcgcgagca agcccgctcc
    14581 cacagagcaa tgcattccaa aatgcgggag cggcggtgcg acgattcgac ttgctcgcga
    14641 aagcgtcatc cgccgcgttg aaaaacgtca gtcgaacacg aagagagcat catcgctgaa
    14701 ttgcacttca aaccggtcag ccggcatcgg ccgcccgaac agataaccct ggacctcatc
    14761 gcaaccgtgt tccctcagga agtccagctg ctcctgggtt tccacacctt cggcgatcac
    14821 cgccaggttg aggctgtggg ccatggcgat gatcgcccgg gcgatctgcg cgtcctgttc
    14881 gcccgatggc aggccgtcga cgaaggtgcg gtcgattttc agcacgtcga tcgggaactg
    14941 cttgaggtag ttgagcgatg agtaaccggt gccgaagtcg tcgaccgcaa tgctcaggcc
    15001 gagatttttc aagccgtcga ggatctgcat cgcctcgctg acttcgcgca tcaggatact
    15061 ttcggtcagc tccagttcca ggcacgccgg tggcaggccg gtgtccttga ggatggtggc
    15121 gattcgcgta ccgagctgac cgtcggagaa ctgtcgcgcc gagatgttca ccgacacctt
    15181 cggcacccgc actttggcct gatgccaggt cttgagctgg cggcatgcct cgctgatcac
    15241 ccagtcgccc acgtccacca ccaggccgag ctcttcgagc accgggatga agtccccggg
    15301 cggtaccagg ccgcggcgcg gatggcgcca gcgcaacagg gcttcggcgc cggtcaaacg
    15361 tttgccatcg ccgctgaatt gcggttggta atacaggacg aactcgttct gctccagggc
    15421 atggcgcagg tcactttcca gttccaggcg ctccagggcg ctggcgttca tgtccgcctg
    15481 atagaactgg aagttgttct tgccgcgctc cttggcgtgg tacatcgcgg tgtcggcgtt
    15541 cttcatcagc tggctgagtt cgttgccgtc ctgcgggctc agggcgatgc cgatactggc
    15601 cgtgacgaag aactcacggc cttcgagcac gaacggtttc accaggctgg cgagaatctg
    15661 ttctgccaca tgaattgccc ggttcagggc aatctcccgg ttggcccgtg gttgcagcag
    15721 cagggtgaac tcatcgccgc ccatgcgcgc cacggtgtcg tcgtcatcga cgcaccccag
    15781 caggcgcgtg gccatgtcct tgagcatgcg gtcgccggcg gcatggccca gggagtcgtt
    15841 gatcggcttg aaacggtcca ggtcaaggaa catcagcacc acccacgact tttgccgttc
    15901 ggccgcttgc agcgcggtgt gcaggcgatc ctggaacagg gtgcggttgg gcaggtgggt
    15961 cagggcatcg taataggcga ggcgatgaat ccgctgctca ctggccttgc gctcgctgat
    16021 gtcgctgaaa aagcacacgt agctggccag gtcgccttcg tcgtccagta ccgcggtaat
    16081 gccgacccac gccgggtaat gttcgccatt acggcgcttg agccagactt cgccttccca
    16141 ggtgctgttc tggttaagtt gcttgagcac gtaatgcaga tgcgcttcct gttcctggtc
    16201 gacggtcagc atgttcggca actggtcgag tacttgctcc accgcataac cgctgacgcg
    16261 actgaaggct tcgttggcct gaacgatgta gccggccggg tcggtgatca ggatcgccga
    16321 ggtcgagtgc tcgaataccg tggcggccat gcgcaggtct ttttcggcgc ggcgctgctg
    16381 gctgatgtcg cgaccgacac cgagcacgcc ttcgaaggtg tcgtgttcgt cccagaccag
    16441 caccagccgc agttcgatgg gaatcttgcg cccgtcggcc cgcaggcagt cgaacaggaa
    16501 catctgggtc tgcacctggg tgcgcaacag ggccagttgt tcaggttgat ccagggcttt
    16561 gctgacccgc tccatcaggc tgtagatgcc ggccagttgc tgcgggttgg cgatggtcga
    16621 ttgccagccg ttctggaaaa tccattcggc gtcgtagccc agcaccgctt gcaccgaggg
    16681 gctgacgtaa ttgagtgaca tgcggttgtc ggtggagatg atcacgtcgc tgatgctttc
    16741 ggcgagcatc cggtagcgct gttcgctgtc gcgcagggac tcactggcct cgatctgctc
    16801 ggtgacgtcc ttggccacgc cgatgatgcg ggtcacctgg tcgtgcttgt cccgtgccag
    16861 ggcttgttcg cgaatgtcga aacgccgcca ttccccgtcc cggtgacgga agcgcagctg
    16921 gcattgcatc aattggctgt agccgccttg ccgctggttc tggcgcgagc ggtggtagta
    16981 atcggcatcg tcggggtgga ggaggatttc ccagaaatac tcgcccatgt gctgcagttc
    17041 ggtgcggttg tagcccaggg tctggcccag atggtggttg ctgaagatca tgcgctggct
    17101 gatcacgtcc tgtacgtaca ggtgatcggg cacggtgcgc accacatcgg accagaatcc
    17161 ttcgcgctcc agcagtgaca actcgatgag cttgcggctg gtgatgtcgg tgatgctcag
    17221 gatcaccgct ttgaagcctt cggcgttttg tggcaggcgc aacaccagcc acaggtgctg
    17281 gtcgcggccg gtcgcgtcct ggagcttgat ttccagttcc agttgctgct gttgattgag
    17341 caccgcttcg agcacctggt tgccgatggc gctgccgtcc agcgggttgc catcgatcag
    17401 caagtcccag gcttgtccgg aggtactgac gttgagcaac tgcagggcca cctggttgac
    17461 ttcggtaatg cgcagcgcct ggagcagctg caggcgctgt tcccggtcct ccagccaccc
    17521 ttgcagttgc tcctgactct gcaaccgggc cttgtcgaac gcgctcttga ggccagacat
    17581 gtcgagtaca cacagcgcga cgcccgtgcc ttcgaagatt tcctgataac ggcggcgacc
    17641 ttcatgcagc tggcgctggc gccggcgcat gttcagcagg acgataaacg gcagcatgga
    17701 gaaggccagg cacaacaggc atttgccgat gaaggccggc agcagttcct cgagcacccg
    17761 ctggcgatcg aacagcccgc gcagctgcca gtcactgccg ctcagcggaa cggtcagtac
    17821 gctgttgctc acgtcgtctt gggtgagcat gcccgggttg accaggggca gcgcttcatc
    17881 gcggctgatg atctggtggt tgaagcggtt ttccaccagc cattgcggac ggccatcggt
    17941 cccgttcagc tgggtcaggg acgagaaaaa cctcggattg aagcgcaagg cccagtagcc
    18001 acgggtactg ccgctggctt gatgcagcaa cagatgcacc accgagccat cgatggcatt
    18061 gctgaaataa tgaggctggg cacgactgcg ccggaccagt tcgctcaggt aatccgcgtc
    18121 ttcgctgttg gtcgcgctgt cggtcaggat ggttccggac gggctgagca gggcgaggct
    18181 ggtcaggtcg ggcaaggact tttgcagctt gcgcagcagc tcctgctgtt cttcgatact
    18241 ttgcggctgt tcaacgatcg gtagcagatt aagggcgatc tgcgcgttga gcgccatgtt
    18301 caggctgact tgcgcggcca ggtcggcggt gtagtcgatg gtgtattggc gctgggtttt
    18361 ctggttttcg cgcagctggt ccagcagctg ccagaacagc agtgcaagca gtaaaagcac
    18421 gaggctcgcc aaggcacttt tcagggttcc gcgcaggggc gaaccgttcg ctgttgaagg
    18481 tgcactggtg gtcaggggcg gaaggacact ggacaagctt tgatcctgcg gtttggctgg
    18541 actggcgcga cgtgcactat aagccggacg cccgaagggc ggctagcatg ccttgagttg
    18601 tggcaaagtg ccagccccac tcggctggac ggccatctgt cattgaggta gctttgccgg
    18661 ttacgcggga gcgttccagc tcctagaatc agactttttt cagcgcgcac gcattgatcc
    18721 ccatcaagcg gccgacgcgc acggtctggc caggcatcgc ctgcgcttta ttattcatct
    18781 gtcactgacc ctaggttctc catggctcaa tacgtattca ccatgcatcg gctgggcaaa
    18841 gttgtgccgc cgaagcggga aatcctgaaa aacatctccc tgtcgttctt cccgggcgcc
    18901 aagatcggcg tgctcggtct caacggttcg ggtaaatcca cgctgttgaa aatcatggcc
    18961 ggcgtcgaca ccgagttcga gggcgaagcc cgtccgatgc cggagctgaa catcggttac
    19021 ctgccacagg aaccgatcct ggacccgacc aagaccgtgc gtgaagtggt cgaggaagcg
    19081 gtcagcgtga tcaagaacgc ccaggcacgc ctggacgagg tctacgcggc ttacgcggat
    19141 gaggatgccg acttcgacaa actggccgct gaacaggcca agctcgaagc catcctgcaa
    19201 gcgggcgacg gtcataacct ggagcgccag ctggaagtcg ccgccgatgc actgcgcctg
    19261 ccggcgtggg atgccaaggt tgaattcctt tccggtggcg agaagcgtcg tgtggccctg
    19321 tgccgcctgc tgctgtccgc cccggacatg ctgctgctcg acgaaccgac caaccacctg
    19381 gacgccgatt ccgtcgcctg gctggagcac ttcctccacg acttcccggg caccgtggta
    19441 gcgatcacgc acgaccgtta cttcctggac aacgtcgccg gctggattct ggaactcgac
    19501 cgcggcgcag gcattccgta cgaaggcaac tattcgggtt ggctggaagc caagtcggat
    19561 cgtctggcgg ccgaatccaa gcaacagtcg gctcacgaaa aagccatgaa ggaagaactg
    19621 gagtgggtgc gcaaaggcgc gaaggcccgc cagtcgaaat ccaaggctcg cctgcaacgc
    19681 ttcgaagaaa tgcaatcgca ggaattccag aagcgcagcg aaaccaacga gatctacatc
    19741 ccggccggtc cgcgcctggg cgacaaggtc atcgagttca agaacgtcac caagggttac
    19801 ggcgatcgcg tgttgatcga caacctgtcg ttctccatgc ctaagggcgc catcgtcggc
    19861 gtgatcggcg gtaacggtgc cggtaagtcg accctgttcc gcatgctgat gggcaaggaa
    19921 acaccggatt cgggcagcat cgaagtcggc gaaaccgtgc aactggcgtg cgtcgaccag
    19981 agccgcgaag acctcgacgg cagcaagacg gtgttccagc agatttccga cggttccgac
    20041 cagatccgca tcggcaacta cgagatcccg tcgcgcacct acgtcggtcg cttcaacttc
    20101 aagggcggcg accagcagaa gttcgtcaag gacctgtccg gtggtgagcg cggtcgcttg
    20161 cacctggcct tgaccctgaa ggagggcggc aacgtcctgc tgctcgacga accgtccaac
    20221 gacctcgacg tcgaaaccct gcgttccctg gaagaagcct tgctggactt cccgggcgcc
    20281 gccattgtga tctctcacga tcggtggttc cttgaccgcg tcgcgactca catcctggcg
    20341 tacgaagacg actcgcaagc cgtgttcttc gaaggcaact acaccgagta cgaagccgat
    20401 cgtaaaaagc gtctcggcga agcggctgca cagccgcacc gtgtacgcca caagaaactg
    20461 gcctgatatc gggtgggttg catgaaaaag cggagccttc gggctccgtt tttttttgcg
    20521 tgtctttcag tgcctctgcg gtgggcccat agcgagcaag cccgctccca catttggtcg
    20581 cattccacct ggaggaacgg ggtcaaaagt gggagcgggc ttgctcgcga atgcagtctt
    20641 cataacggtg cgaatcttgg tttgtgaatc ccttttcagg tgcaaaaacg gtcggaaaac
    20701 acgatcaatt tatatcctgt gcaccattta atttcataaa cgcgacattc tgctctgttc
    20761 ttgtgcacgt ttcgtttgtt aaagtccggc ccaatttctt ccaacgacaa taatttgccg
    20821 agccttttcc atgatcgaat ccgtcgaatc cttccttgcc cgcctgaaaa aacgcgatcc
    20881 ggaccaacct gaattccacc aggccgtcga agaagtcctg cgcagcctct ggccctttct
    20941 cgaggccaat ccccactatt tgacctccgg gattctggag cgaatttgcg agccggagcg
    21001 ggcgatcgtg tttcgcgttt cctgggtcga cgatcacggc aaggtgcagg tcaatcgtgg
    21061 tttccgcatc cagatgaaca gcgccatcgg tccgtacaag ggcggtttgc gcttccatcc
    21121 ttcggtcaac ctcggcgtat tgaaattcct cgcgttcgag cagaccttca agaactcgct
    21181 gacctcgttg cccatgggtg gcggcaaggg cggttcggac ttcgatccaa aaggcaaaag
    21241 cgacgcggaa gtcatgcgct tctgccaggc cttcatgagc gagttgtacc gtcacatcgg
    21301 tgccgacgtt gacgtgccgg ccggtgatat cggcgtcggt gcccgggaaa tcggtttcct
    21361 gttcggccag tacaagcgcc tgggcaacca gttcaccagc gtgctgaccg gcaagggccc
    21421 aagctacggc ggcagcctga ttcgtccgga ggccaccggt ttcggttgcg tctacttcgc
    21481 cgaagagatg ctcaagcgtc gcggcctgac ggtcgaaggc aagcgggtag cgatctccgg
    21541 ttccggcaac gtcgcacagt acgcggcccg caaggtcatg gacctgggcg gcaaagtgat
    21601 ttcgctgtcg gattccgaag gcacgctcta ctgcgagagc ggtttgaccg aggagcagtg
    21661 gcaagcggtg ctggagctga aaaacgtcca gcgcggacgc atcagcgagc tggctggccg
    21721 atttggcctg gagttcctcg ccggtcagca cccgtgggaa ctgagctgcg acatcgcgct
    21781 gccgtgcgcc acgcagaacg aactggatgc cgatgccgct cgcactttgc tgcgcaatgg
    21841 ctgcgtctgt gtggccgaag gcgccaacat gccgaccacg cttgaggcag tggacctgtt
    21901 tatcgacgcc ggcatcctgt tcgcgccggg caaggcttct aacgcgggtg gggtggccgt
    21961 gagcgggctg gagatgtcgc agaacgccat gcgcctgctg tggaccggcg gtgaagtgga
    22021 cagcaagctg cacgccatca tgcagtcgat ccaccacgct tgcgtgcatt acggtgaaga
    22081 gaacggtcag gtcaactacg tgaagggcgc gaacatcgcc ggtttcgtca aggtcgccga
    22141 cgccatgctc gcccagggcg tggtctaaac cggttcgata cggacgatcc cgatcaactg
    22201 atcgcccgcc gggcgttgcc acagcacctc gtcaccgagt tgcgccccga gcaacgcccg
    22261 gcccagcggc gatccccaat tgatcaggcc tttggcggca gcggcctggt cttcaccgac
    22321 caattgcacg cggtgctcgg tgccttgctc atcgacgtag gtgacccggc tgccaatctg
    22381 caccttgctg gtcgacgtcg ccgcgggcac cacctgagcg ctttgcaggc gttggtgaaa
    22441 gtaacgcaga tcccgttcaa ggttggccag cagctgcttg tcagcctgat cacccctcgc
    22501 cgattgttgg gcgtgcaatg cctgcaactc ggcgaccttt tcctgcagca gatccaggcc
    22561 agcgccagtg acgtaattgg gctgcgcgct gacctgccgt tcgaccggct gatcggcttg
    22621 cgcggcggcg ttatcttcat tgacgaaggc gcgactcatg gttttctccc gagatagggt
    22681 ttgggccatg gttgcaggct tttggtttca atggatgtct gtcagcgacc tattgcgagc
    22741 gataggcccg ggcggcgtcc tgatcctttt gctgttgcca ggctttatcg cgctcgttcc
    22801 aatggctgtt gcgatagtcc gcgcggtcct ggttctcgcg catggcctgg cactggcgaa
    22861 aaccgtcact ccagccttcg gcgtagttgt tgtctttcag gtaacgcggg acatttttgc
    22921 gaaactcgcc ggtgatggcg ccggcggctt gccggccact gctgcagccg tcatcgaaac
    22981 cgtcggcgaa cgccggtgga taacccttgg cgatcaggtc ttcgtgggtt gtctgg
//
