LOCUS       NZ_CABVIY010000003     22133 bp    DNA     linear   CON 07-NOV-2023
DEFINITION  Pseudomonas fluorescens isolate PS918, whole genome shotgun
            sequence.
ACCESSION   NZ_CABVIY010000003
VERSION     NZ_CABVIY010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Pseudomonas fluorescens
  ORGANISM  Pseudomonas fluorescens
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
REFERENCE   1
  AUTHORS   Chandra,G. and Truman W,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2019) JOHN INNES CENTRE, NORWICH, UK., Molecular
            Microbiology, Norwich Research Park, Norwich NR4 7UH, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/07/2023 08:57:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,059
            CDSs (total)                      :: 5,986
            Genes (coding)                    :: 5,920
            CDSs (with protein)               :: 5,920
            Genes (RNA)                       :: 73
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 7 of 66
            Pseudo Genes (incomplete)         :: 63 of 66
            Pseudo Genes (internal stop)      :: 6 of 66
            Pseudo Genes (multiple problems)  :: 8 of 66
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:35:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 220974
            Orig. end                         :: 243107
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CABVIY010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22133
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="1"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22133
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22133
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12133](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12133
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     misc_feature    complement(1242..1255)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            1723..2184
                     /gene="pedF"
                     /locus_tag="F8N66_RS11920"
                     /old_locus_tag="PS918_02279"
     CDS             1723..2184
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene="pedF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010209355.1"
                     /locus_tag="F8N66_RS11920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02279"
                     /product="cytochrome c-550 PedF"
                     /protein_id="WP_150770359.1"
                     /transl_table=11
                     /translation="MTTKRNALLVTGLLAGLLCAGSVWAHGNVVPQAVATQGLTPIKEA
                     GVPLDADGWAAVNPYRTAPEHDKAVEIGASAYNQNCAACHGLEAKSGGIAPDLRMLDVG
                     EAGDEWFVERVRHGAVRDGRVYMPKMADYLSQEALWAVRSYLDSVHVEE"
     gene            2188..3063
                     /locus_tag="F8N66_RS11925"
                     /old_locus_tag="PS918_02280"
     CDS             2188..3063
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020800572.1"
                     /locus_tag="F8N66_RS11925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02280"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_150770360.1"
                     /transl_table=11
                     /translation="MRLLAVLISAVWLCCQSVQAQVRNYDEMIAAGELKVAVYKDFAPY
                     SFEQAGQPRGVDVELAQALAKALGVRLVLIWAPAGEKLDDDLRDYIWRASQLHNQQLAD
                     LMMRVPYDRDYAQKRNEFGELENGHVVMFGPYQNEQWQVAYDRRRLDKVASVAVFEQHP
                     IGVEVDSVPSFYLTSVFNGMLAGKTRHYPGVPQAFAAMKAGEVDAVMAMRGEIDWQVHQ
                     AADPQLALAENAYPNMGKQVWEIGMAVHESNRQLAYAVEEALESLIRDGSVNTLYGHYG
                     LRYDVPDMYQ"
     gene            3073..3834
                     /locus_tag="F8N66_RS11930"
                     /old_locus_tag="PS918_02281"
     CDS             3073..3834
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008149750.1"
                     /locus_tag="F8N66_RS11930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02281"
                     /product="quinoprotein dehydrogenase-associated SoxYZ-like
                     carrier"
                     /protein_id="WP_150770361.1"
                     /transl_table=11
                     /translation="MKWQRRCLLACCLSLAAHAAAVDPGKDPVPSVMWAFYHKQMLGDA
                     PFVFDERVKLLAPPFAEDARQVPLEIDARAFKGDVVRILAWAELNPLPKIVDFQPLSGV
                     LPWLSIRIRVEQATPLRAAVLTRDGLWHVGSTLIDAAGGGCTAPSVVRTQPGWEERIGE
                     VLGGRYPRQDFSRLRVQVAHPMDNGMVGGIPEFFINHAQLRDQHDQPLARLELFPAVSE
                     NPSLGFDIEGAGQTRLLLRDNSGNQFDAAIP"
     gene            3851..4786
                     /locus_tag="F8N66_RS11935"
                     /old_locus_tag="PS918_02282"
     CDS             3851..4786
                     /codon_start=1
                     /gene_functions="resistance (resist) SubclassB1"
                     /gene_kind="resistance"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008036749.1"
                     /locus_tag="F8N66_RS11935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02282"
                     /product="quinoprotein relay system zinc metallohydrolase
                     1"
                     /protein_id="WP_150770362.1"
                     /transl_table=11
                     /translation="MRWMLLLLIALGLPAMADLEYSLKPRLIAPDTWLLEGSTDNFGKD
                     NGGNIVNTAFIVTERGVVVIDTGPSKRYGEALRRAIAATTDKPVIQVLLSHHHPDHVLG
                     NQAFSDVPIGALAGTTELLQKQGDAMAENMYRLVGDWMRGTEVVLPNQTLVPGVSSFGN
                     HDLRLLSLGGHTGADLAILDQQTGVLFAGDLVFYQRALTTPNSPGLSVWLADLATLQGL
                     PWTLIVPGHGPLASDARPFEQMHDYLSWLDQLMGEGAANGSDMAEMIRSPIPERFAGIS
                     LGRYELIRSVSHLYPRYERAQMTRVDSTNP"
     misc_feature    complement(3873..3888)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.92"
                     /tool="antismash"
     gene            5033..6808
                     /locus_tag="F8N66_RS11940"
                     /old_locus_tag="PS918_02283"
     CDS             5033..6808
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017847477.1"
                     /locus_tag="F8N66_RS11940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02283"
                     /product="PQQ-dependent methanol/ethanol family
                     dehydrogenase"
                     /protein_id="WP_150770363.1"
                     /transl_table=11
                     /translation="MTQPVRRQPFVLSMLLSAMLLSGQALAGVSDQDILQDPKNPEQIV
                     TNGLGVQGQRYSPLDILNVDNVKELRPAWAFSFGGEKQRGQQAQPMIKDGVMYMTGSYS
                     RVFAVDARTGKKLWQYDARLPDDIRPCCDVINRGVALYGDLVIFGTLDAKLVALNKDTG
                     KVVWSKKVADHKEGYSISAAPLVINGKLITGVAGGEFGVVGKIEAYDPKNGDLLWTRPT
                     VEGHMGYLYKDGKAVENGISGGEAGKTWPGDLWKTGGAAPWLGGYYDPETNLLLFGTGN
                     PAPWNSHLRPGDNLYSSSRLALNPDDGTIKWHFQSTPHDGWDYDGVNELVSFNYSEGGK
                     EIKAAATADRNGFFYVLDRTNGKFIRGFPFVDKITWATGLDKAGRPIYNEASRPGAPGS
                     EAKGSSVFVAPAFLGAKNWMPMAYNRDTGLFYVPSNEWGMDIWNEGIAYKKGAAFLGAG
                     FTIKPLNEDYIGVLRAIDPKTGKEVWRHKNFAPLWGGVLTTKGNLVFTGTPEGFLQAFN
                     AKTGEKVWEFQTGSGVLGSPVTWEMDGEQYVSVLSGWGGAVPLWGGEVAKRVKDFNQGG
                     MLWTFKLPKDLVAKH"
     gene            7066..8586
                     /locus_tag="F8N66_RS11945"
                     /old_locus_tag="PS918_02284"
     CDS             7066..8586
                     /EC_number="1.2.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_250674.1"
                     /locus_tag="F8N66_RS11945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02284"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_150770364.1"
                     /sec_met_domain="Aldedh (E-value: 3.3e-166, bitscore:
                     548.9, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIYAQPGTPGAVVSFKPRYGNFIGGEFVAPVNGEYFTNTSPVNGE
                     VIAEFPRSGAADIDKALDAAHAAADAWGKTSAQDRSRVLLKIADRIEQNLEILAVTETW
                     DNGKAVRETLNADVPLAADHFRYFAGCIRAQEGGAAEINELTTAYHFHEPLGVVGQIIP
                     WNFPLLMAAWKLAPALAAGNCIVLKPAEQTPLSIMVFAELIADLLPAGVLNIVQGFGRE
                     AGEALATSKRIAKIAFTGSTPVGAHIMHCAAENIIPSTVELGGKSPNIFFEDIMNAEPA
                     FIEKAAEGLVLAFFNQGEVCTCPSRALVQESIYEPFMAEVMKKIVKIKRGNPLDTETMV
                     GAQASEQQYDKILSYLTIAQEEGAQLLTGGAAERLEGDLSSGYYIQPTLLKGTNNMRVF
                     QEEIFGPVVGVTTFKDEAEALAIANDTEFGLGAGLWTRDINRAYRMGRAIKAGRVWTNC
                     YHLYPAHAAFGGYKKSGVGRENHKMMLDHYQQTKNLLVSYDINPLGFF"
     misc_feature    8589..8605
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.66"
                     /tool="antismash"
     misc_feature    8634..8643
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            8833..8904
                     /gene="pqqA"
                     /locus_tag="F8N66_RS11955"
     CDS             8833..8904
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_250675.1"
                     /locus_tag="F8N66_RS11955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_003253598.1"
                     /transl_table=11
                     /translation="MWTKPAFTDLRIGFEVTMYFANR"
     gene            8960..9874
                     /gene="pqqB"
                     /locus_tag="F8N66_RS11960"
                     /old_locus_tag="PS918_02285"
     CDS             8960..9874
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010455121.1"
                     /locus_tag="F8N66_RS11960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02285"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_150770365.1"
                     /transl_table=11
                     /translation="MHIRVLGSAAGGGFPQWNCNCRQCAGVRNGSLRAQRRTQSSIALS
                     DNGVDWVLCNASPDIRAQLDSFPPLQPARRLRDSAIAAVVLMDSQIDHCTGLLSLREGC
                     PHDVWCTERVHQDLSSGFPLFTMLSHWNGGLQWQPIGLTREPFYIPTCAHLQFRAIPLV
                     SNAPPYSPNRGHPQPGDTIGLFIEDQRSGASLFYAPGLGQVDDELLDWMQRADCLVLDG
                     TLWRDDEMRLCEVGQSLGSEMGHLAQSGPGGMLEVLEGFPRQRKVLIHINNTNPILDED
                     SAERALLERRGIEVAYDGMDIVL"
     gene            10001..10744
                     /gene="pqqC"
                     /locus_tag="F8N66_RS11965"
                     /old_locus_tag="PS918_02286"
     CDS             10001..10744
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019366409.1"
                     /locus_tag="F8N66_RS11965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02286"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_150770366.1"
                     /sec_met_domain="TIGR02111 (E-value: 3.1e-122, bitscore:
                     402.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMTPAEFEQALRAKGAYYHIHHPFHQAMYAGQATREQIQGWVAN
                     RFYYQVNIPLKDAAILANCPDRDVRREWLQRILDHDGAPGSEGGIEAWLRLGEAVGLDR
                     EQILSQELVLPGVRFAVDAYVNFARRACWQEAASSSLTELFAPQIHQSRLDAWPTHYPW
                     IDVAGYDYFRTRLGQARRDVEHGLRITLAHYVTLEAQQRMLEILQFKLDVLWSMLDAMS
                     MAYELERPPYHTVTRDNVWHRGIAL"
     gene            10741..11013
                     /gene="pqqD"
                     /locus_tag="F8N66_RS11970"
                     /old_locus_tag="PS918_02287"
     CDS             10741..11013
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020800245.1"
                     /locus_tag="F8N66_RS11970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02287"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_150770367.1"
                     /sec_met_domain="PqqD_RRE (E-value: 5e-33, bitscore: 108.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.2e-17, bitscore: 56.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLIDRELSPSLRRGFRLQWEPRQDCHVLLYPEGMIKLNASAAQI
                     LELLDGQRSVAAIIDRLTADFPGVPGIDEDVLAFLEVAHAQFWIE"
     aSDomain        10747..11010
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_F8N66_RS11970_PqqD_RRE.1"
                     /evalue="1.80E-34"
                     /identifier="RREFam006.1"
                     /label="F8N66_RS11970"
                     /locus_tag="F8N66_RS11970"
                     /protein_end="90"
                     /protein_start="2"
                     /score="108.4"
                     /tool="antismash"
                     /translation="LIDRELSPSLRRGFRLQWEPRQDCHVLLYPEGMIKLNASAAQILE
                     LLDGQRSVAAIIDRLTADFPGVPGIDEDVLAFLEVAHAQFWIE"
     gene            10991..12133
                     /gene="pqqE"
                     /locus_tag="F8N66_RS11975"
                     /old_locus_tag="PS918_02288"
     CDS             10991..12133
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008017486.1"
                     /locus_tag="F8N66_RS11975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02288"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_150770368.1"
                     /sec_met_domain="PF04055 (E-value: 2.4e-24, bitscore: 82.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1e-07, bitscore: 27.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 4.2e-11, bitscore: 38.8,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 8.9e-09, bitscore:
                     31.3, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNSGSSEALPGPPLWLLAELTYRCPLQCPYCSNPLDFARHGEEL
                     GTEEWIRVFREAREMGAAQLGFSGGEPLVRQDLAELIKAARGMGYYTNLITSGIGLTEQ
                     KVRDFKDAGLDHIQISFQAADEAVNNMLAGSRKAFAQKLAMARAVKAQGYPMVLNFVTH
                     RHNIDRIDRIIDLCLELEADFVELATCQFYGWAELNRVGLLPTREQLQRAERITNEYRE
                     RLEDQGHPCKLIFVTPDYYEERPKTCMNGWANLFLDITPDGTALPCHSARQLPVQFPNV
                     REHSISHIWNDSFGFNRFRGDAWMKEPCRSCDEKHKDLGGCRCQAFMLTGDAENADPVC
                     SKSPHHGVILKAREEAEAPGLGMEHLTLRNEKASRLIYRG"
     gene            12344..13507
                     /gene="ercA"
                     /locus_tag="F8N66_RS11985"
                     /old_locus_tag="PS918_02289"
     CDS             12344..13507
                     /codon_start=1
                     /gene="ercA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_250681.1"
                     /locus_tag="F8N66_RS11985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02289"
                     /product="alcohol dehydrogenase-like regulatory protein
                     ErcA"
                     /protein_id="WP_150770370.1"
                     /sec_met_domain="Fe-ADH (E-value: 5.9e-117, bitscore:
                     386.1, seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSLSQLRKFVSPEIIFGAGCRHNVGNYAKTFGARKVLVVSDPG
                     VIAAGWVADVEASLQALGIEYCLYSAVSPNPRVEEVMLGAELYRENHCDVIVAVGGGSP
                     MDCGKGIGIVVAHGRSILEFEGVDTIRVPSPPLILIPTTAGTSADVSQFVIISNQQERM
                     KFSIVSKAVVPDVSLIDPETTLSMDPFLSACTGIDALVHAIEAFVSTGHGPLTDPHALE
                     AMRLINGNLVQMIANPTDIALREKIMLGSMQAGLAFSNAILGAVHAMSHSLGGFLDLPH
                     GLCNAVLVEHVVAFNYSSAPERFKVIAETFGIDCRGLNQRQICGRLVEHLIALKHAIGF
                     HETLGLHGVRTSDIPFLSQHAMDDPCILTNPRESSQRDVEVVYGEAL"
     gene            13491..15227
                     /locus_tag="F8N66_RS11990"
                     /old_locus_tag="PS918_02290"
     CDS             13491..15227
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015095424.1"
                     /locus_tag="F8N66_RS11990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02290"
                     /product="NahK/ErcS family hybrid sensor histidine
                     kinase/response regulator"
                     /protein_id="WP_150770371.1"
                     /transl_table=11
                     /translation="MAKPSDEQQRALAGLLGLGSHSARKSHYPELAARLDELEAERNRY
                     KWLFENAVHGIFQASLHEGLRAANPALAHMLGYQDPQEVLFSLNDLASHLFAGGAQELE
                     TIGDLLKRQRSLHGYETRLRRKDGSHLDVLMNLLLKPGQEGLVEGFVADITERVQAQQR
                     LQQLNDELEQRVAARTDELLEANRNLQQQITQRKQIAQALRDARDAAEAANRSKDKYLA
                     AASHDLLQPLNAARLLISTLRERQLPEVEQVLVERTHQALEGAEDLLTDLLDISRLDQA
                     AVKPDIALYRLDELLGPLVSEFQSVAQAAGLNLRVHTGDYAISTDLRLMTRILRNFLSN
                     ACRYTDEGSILLGARRRGEYLRLEVWDTGRGIAADRLDSIFLEFNQLDVGRAADRKGVG
                     LGLAIVERIARILGYPIGVHSLPGRGSMFSIDVPLSHDIPLPIDQAAPQPVTGNPLPGR
                     RLLVLDNELSILESMSALLGQWGCEVVTATDEASALAALAGRAPELILADYHLDHAVVG
                     CDVVRHLREHFHQRIPAVIITADRTDQCRRSLQRLEAPLLNKPVKPGKLRAVLSQLLAA
                     PA"
     gene            complement(15203..16087)
                     /locus_tag="F8N66_RS11995"
                     /old_locus_tag="PS918_02291"
     CDS             complement(15203..16087)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007972172.1"
                     /locus_tag="F8N66_RS11995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02291"
                     /product="aldose 1-epimerase"
                     /protein_id="WP_150770372.1"
                     /transl_table=11
                     /translation="MKLIELEDEYTRLTLAPELGASIVNWSVRSTGQPLLRHTDAPALH
                     SGLPGKLGCFPLAPWSNRIAEGGFDCPDGWLALTPNSPGDPLPIHGTAWQQAWQVVSHR
                     HDEVVLQLDSTTPFAYRARQRLHLSQGRLGIELQVTHLAARPAWHGLGLHPYFPRLAST
                     RLQAHAEQVWLCEASRLPTGLASVPAPWDFRQLQALPETLVDNGFCQWNGHCLIRQPDL
                     GYELECQASGSDYYLLYCPPGLDFFCLEPVSHPVNAHHLPGRPGLRLLEQGQSTELGFS
                     LRYRALQAGAANS"
     gene            16188..16808
                     /locus_tag="F8N66_RS12000"
                     /old_locus_tag="PS918_02292"
     CDS             16188..16808
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_249127.1"
                     /locus_tag="F8N66_RS12000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02292"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_150770373.1"
                     /transl_table=11
                     /translation="MGNHKIEIRRSNVEKILLGAEKVFAEKGFGSTAMADIAAEVQLPR
                     SNLHYYFSTKTELYSAVLFDLLEVWKQDALCFEMFDDPRVVLSSYIRAKMNHSRSRPYG
                     SKVWANEIIHGAPTLGEALDASLYDWAKMKEAKIRQWVDDKRILPVEPSSLLYMIWAST
                     QHYADFDHQVNILNDHQPLSDMQFERAVQTVTSVILRGIGLEP"
     gene            complement(16916..18190)
                     /gene="preA"
                     /locus_tag="F8N66_RS12005"
                     /old_locus_tag="PS918_02293"
     CDS             complement(16916..18190)
                     /EC_number="1.3.1.1"
                     /GO_function="GO:0017113 - dihydropyrimidine dehydrogenase
                     (NADP+) activity [Evidence IEA]"
                     /GO_process="GO:0006210 - thymine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006212 - uracil catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="preA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009048418.1"
                     /locus_tag="F8N66_RS12005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02293"
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
                     /protein_id="WP_150770374.1"
                     /transl_table=11
                     /translation="MADLSIVFAGIKSPNPFWLASAPPTDKAYNVVRAFEAGWGGVVWK
                     TLGEDPAAVNVSSRYSAHFGANREVLGFNNIELITDRSLEINLREITQVKKDWPDRALI
                     VSLMVPCVEESWKHILPLVEATGADGIELNFGCPHGMPERGMGAAVGQVPEYVEQVTRW
                     CKTYCSLPVIVKLTPNITDIRVAARAAHRGGADAVSLINTINSITSVNLERMVANPVVG
                     SQSTHGGYCGSAVKPIALNMVAEIARDPQTQGLPISGIGGIGNWRDAAEFIALGSGSVQ
                     VCTAAMLHGFRIVEEMKDGLSRWMDSQGYASISEFSGRAVANTTDWKYLDINYQVIAKI
                     DQEACIGCGRCHIACEDTSHQAVASLKKADGTHAYEVIDEECVGCNLCQITCPVQDCIE
                     MVPVETGKPFLDWNHDPRNPYHVAV"
     gene            complement(18191..19558)
                     /locus_tag="F8N66_RS12010"
                     /old_locus_tag="PS918_02294"
     CDS             complement(18191..19558)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_249131.1"
                     /locus_tag="F8N66_RS12010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02294"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_150770375.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.3e-34, bitscore:
                     114.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKTLTHLPHPYENAAALAGHFTDLAPPLNDRQAHLEASRCLYCY
                     DAPCVNACPSEIDIPSFIRNIHQDNVQGAAQKILSANILGGSCARVCPTEILCQQACVR
                     NNAHECAPVLIGLLQRYAVDNAHFSQHPFSRAAATGKRIAVVGAGPAGLSCAHRSAMHG
                     HDVVIFEAREKAGGLNEYGIAKYKLVDDYAQKELDFLLEIGGIEIRHGQKLGENLSLSE
                     LHQQFDAVFLGLGLAASKQLGLLHEDAPGLVAATDYIRELRQADDLTQLPLADHCIVLG
                     AGNTAIDMAVQMARLGAHDVNLVYRRGVEDMGATHHEQDIAKANQVRLLTWAQPEDVLL
                     DDQGNVRGMRFARTHLVEGRLQTTGETFELAADAIFKAIGQTFDSSALADPLARELKRQ
                     GDRIQVDEQLRTSIPGVYAGGDCTSLDQDLTVQAVQHGKRAAEAIHAQLMLNVEAA"
     gene            complement(19713..21152)
                     /gene="hydA"
                     /locus_tag="F8N66_RS12015"
                     /old_locus_tag="PS918_02295"
     CDS             complement(19713..21152)
                     /EC_number="3.5.2.2"
                     /GO_function="GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="hydA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_249132.1"
                     /locus_tag="F8N66_RS12015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_02295"
                     /product="dihydropyrimidinase"
                     /protein_id="WP_150770376.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 9.4e-28, bitscore:
                     93.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLIRGATVVTHDESYRADVYCADGVIKAIGENLDLPAGAEVLD
                     GSGQYLMPGGIDPHTHMQLPFMGTVASEDFFSGTAAGLAGGTTSIIDFVIPNPQQSLME
                     AFHQWRGWAEKSASDYGFHVAITWWSEQVREEMAELVSHHGVNSFKHFMAYKNAIMAAD
                     DTLVASFERCLELGAVPTVHAENGELVYHLQRKLMAQGMTGPEAHPLSRPSQVEGEAAS
                     RAIRIAETLGTPLYLVHVSTKEALDEITYARAKGQPVYGEVLAGHLLLDDSVYQHPDWQ
                     TAAGYVMSPPFRPRGHQEALWHGLQAGNLHTTATDHCCFCAEQKAAGKDDFSKIPNGTA
                     GIEDRMAVLWDEGVNTGRFSMQQFVALTSTNTAKIFNLYPRKGAIRVGADADLVLWDPQ
                     GTRTISAKTHHQQVDFNIFEGKTVRGVPSHTISQGRVVWADGDLRAERGAGRYIERPAY
                     PAVFDLLSKRAELNQPVAVKR"
     misc_feature    21283..21296
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.96"
                     /tool="antismash"
     misc_feature    complement(21286..21299)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.4"
                     /tool="antismash"
     misc_feature    complement(21461..21476)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.52"
                     /tool="antismash"
     misc_feature    complement(21462..21476)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.7"
                     /tool="antismash"
ORIGIN
        1 ggtacgccga gcctttcttg tagttgacct cctcggtcca gtactcctcc ttccactggt
       61 taccgggaat gtagaacagc ccggtgtcct ggctgtaggc catggggttc cagttcttgc
      121 cgccgaggaa cggcggcgag acttccaccg gcttgccttt ggtttccccc ggtaacggct
      181 tggccggacg ctggccttcg ttctccaccg ggcggccggt cttgaggtcg atgtggctgg
      241 cccaggtgat gttgtcgacg aaggggaagg cgttctgcaa tttgccgtta ttgcggtcga
      301 ccacatagaa gaaaccgttg cggtcggcgt ggccggtggc cttgaccgtt ttgccgtcct
      361 tgtccttgta gtcgaatagc accagctcgt tgttgccgga gaagtcccag gcatcgttcg
      421 gtgtgtgctg gtagaaccat ttcacttcgc cggtgctcgg atcgacaccg acctggcccg
      481 aggtgtagag gctgtcgtaa tcgtgagggt tgccgtcctt cgacgtgcgc gcccaggtgt
      541 tccacgggcc cgggttgccg gcgccgacga tgatcgtgtt ggtctcggca tcgaaactgg
      601 cgctctgcca aggggcgccg ccgccatggc tccaggcctc gaccttgccg gtttcggtgg
      661 tcgggtcgtt cggccacgac ggcgccttga cgtcgccggt cggtgtactg tccttgccgt
      721 tcaggcggcc catgtggcct tcgacgaacg gccgcatcca gacctcttca ccggtgtccg
      781 ggtcgcgggc gtaaagctgg ccaaccacac cgaactcatc gccggaactg ccatggatca
      841 gcagcacctt gccgctggtc ttgtccttga tcagcaccgg cgcgccggtc atggtgtagc
      901 cggcggcgtg gtcgccgaac ttcttgttcc acaccacttt gccggtgttc ttgtccaggg
      961 cgatcaggcg tgcatcgagg gtgccgaagt agatcttgtc gccaaagatc gccgcgcccc
     1021 ggttgaccac gtcgcagcac gggcgaatgt tgtccggcag gcgatggttg taggtccaca
     1081 ggcgtttgcc ggtcttggcg tccagcgcga atacccgcga gtacgagccg gtgacgtaca
     1141 ccacgccgtc actgacgatg gcctgggatt cctggccgcg ctgtttctcg tcgccgaagg
     1201 agtaggacca ggccggggtc agcttgaaca cgttcttgtc gttgacctgg gccaacgggc
     1261 tccagcgctg ggcattggtg cccatgccgt attgcagcac gtccctggtg gtcaggtgat
     1321 cgttggcaat gtcttcccag ctcacgttgc gggtggccgg tgcgttctcg gcatgccccg
     1381 ccgcgctcag ggacaggctg ccgaccagca aaaaggcctg gatggcgacg gtcaaggggg
     1441 aaagggcggg tagcgatctt attgtcatgt ttgcagttcc cagtggaggt tttgacctgc
     1501 acagggtggg gcgccggcac gttcggcgga tacggaaaaa gtcccgccgt tgccgggaaa
     1561 acttcccatg ggccacctga tttcgacgtc cgtccaaggc cttactacca agggagtaga
     1621 cggcggccac caaagcagca tggggcctgt gcaccggggt ttctaagatg gttgccatag
     1681 cctctgccaa gaggttttgc gtgcaatcct gagggcataa caatgacaac aaaacgcaac
     1741 gccttgctcg tgaccgggct gttggccggt cttctctgtg cgggttccgt ctgggcccac
     1801 ggcaatgtgg tgccgcaggc cgtcgccacc cagggcctga ccccgatcaa ggaggccggc
     1861 gtcccgctgg atgccgatgg ctgggcggcg gtgaaccctt atcgcacggc gccggaacac
     1921 gacaaggcgg tggaaatcgg cgcgtcggcc tacaaccaga actgcgcggc ctgtcatggc
     1981 ctggaagcca agtccggcgg tatcgccccg gacttgcgca tgctcgacgt cggcgaggcc
     2041 ggtgatgaat ggttcgtcga gcgggtgcgc cacggcgccg tgcgcgacgg gcgggtgtac
     2101 atgccgaaaa tggccgacta cctgagccag gaagccctgt gggcggtgcg cagttacctg
     2161 gacagcgtcc acgtcgagga gtgacccatg cgcctgctcg cggtattgat cagcgctgtg
     2221 tggctgtgct gccagtcagt gcaggcgcag gttcgcaact atgacgaaat gatcgccgcc
     2281 ggcgagctga aggtggcggt ctacaaggac ttcgccccct acagctttga acaggccggt
     2341 cagccccggg gcgttgacgt ggaactggcc caggccctgg ccaaggcgtt gggcgtgcgc
     2401 ctggtgctga tctgggcgcc ggccggcgag aagctcgacg acgacctgcg cgattacatc
     2461 tggcgcgcca gccagttgca caaccagcaa ctggccgacc tgatgatgcg cgtgccctac
     2521 gatcgcgact acgcgcaaaa gcgcaacgaa ttcggcgaac tggaaaacgg ccatgtggtg
     2581 atgttcgggc cgtaccagaa cgagcaatgg caagtcgcct atgaccgccg ccgactggac
     2641 aaggtcgcca gtgtcgcggt gttcgaacag cacccgattg gcgtcgaagt cgacagcgtg
     2701 ccgtcgtttt acctgacctc ggtgttcaac ggcatgcttg ccggcaagac ccgccattat
     2761 ccgggtgtgc cccaggcgtt tgccgcgatg aaggccggcg aggtcgatgc ggtcatggcc
     2821 atgcgcggcg agattgactg gcaagtgcat caagcggccg atccacaact ggccctggca
     2881 gagaacgcct acccgaacat gggcaaacag gtctgggaga tcggcatggc ggtgcacgaa
     2941 agcaaccggc aactggccta tgccgtggaa gaggcgctgg aaagcctgat ccgcgacggc
     3001 tcggtgaaca ccctctacgg ccattacggc ctgcgctatg acgtgcccga catgtatcaa
     3061 taggagccgg cgatgaaatg gcaaaggcgt tgtctgttgg cctgctgtct gagcctggcg
     3121 gcccatgccg ccgctgtcga tcccggcaag gacccggtgc cgtcggtgat gtgggcgttc
     3181 tatcacaagc aaatgctcgg cgatgcaccg ttcgtgttcg atgagcgggt caagctgctg
     3241 gcgccgccgt ttgccgaaga cgcacgccaa gtgccgctgg aaatcgacgc ccgggcgttc
     3301 aagggcgacg tggtgagaat cctcgcctgg gccgaactca accccttgcc gaaaatcgtc
     3361 gatttccaac cgctgagcgg cgtgctgccc tggttgtcga tccgcatccg cgtcgaacag
     3421 gccacgccct tgcgcgcggc ggtcttgacc cgcgatgggc tgtggcatgt cggttcgacc
     3481 ctgatcgatg cggccggtgg cggctgcacc gcgcccagcg tggtgcgcac ccagccgggt
     3541 tgggaagagc gcatcggcga ggtgctgggc ggtcgttatc cgcgtcagga tttcagccgc
     3601 ctgcgcgtgc aggtggcgca tccgatggac aacggcatgg tcggcggcat tccggaattc
     3661 ttcattaacc atgcgcagct gcgcgatcaa catgatcaac cgttggcccg cctggaactg
     3721 ttccccgccg tcagcgaaaa ccccagcctg gggtttgata tcgagggggc agggcagacg
     3781 cgtctgttgt tgcgcgataa cagcggcaac caattcgatg cggccattcc ctgacttgaa
     3841 ggagcgtctc atgcgctgga tgctgctgtt gttgatcgcc ctcggcctgc cggccatggc
     3901 tgacctcgaa tactcgctca agccccggct gattgccccc gatacctggc tgctggaagg
     3961 cagcaccgat aatttcggca aggacaatgg cggcaacatc gtcaacaccg cgttcatcgt
     4021 caccgagcgc ggggtggtgg tgatcgatac cgggccgtcg aagcgttatg gcgaagccct
     4081 gcgccgggcg attgccgcga ccaccgacaa accggtgatc caggtcctgc tgagccatca
     4141 tcaccccgac catgtgttgg gcaaccaggc gttcagcgac gtgccgattg gcgcactggc
     4201 cgggaccacc gagctgctgc aaaagcaggg cgatgccatg gccgagaaca tgtaccggct
     4261 ggtgggggac tggatgcgtg gcaccgaggt ggtgctgccg aaccagacgc tggtccccgg
     4321 cgtttcaagt tttgggaatc atgatctgcg cctgctaagc ctgggtgggc ataccggtgc
     4381 ggatctggct attctcgacc agcaaaccgg cgtgctgttt gccggggacc tggtgtttta
     4441 tcaacgggcc ctgaccacgc ccaacagtcc ggggctgtcg gtgtggctgg ccgacctcgc
     4501 gaccctgcag ggactgccct ggaccctgat cgtgcccggc cacgggccgc tggccagcga
     4561 tgcccggccc ttcgagcaaa tgcacgacta cctgagctgg ctcgatcaac tgatgggcga
     4621 gggcgcggcc aatggcagcg acatggccga gatgatccgc agccccatcc ccgagcgctt
     4681 cgccggcatc agcctgggtc gttatgagct gattcgcagc gtcagtcatc tgtacccgcg
     4741 ctatgaacgc gcgcagatga cgcgggtcga ttccacaaac ccctgacctg ccccaatccc
     4801 ctgtgggagc gagcctgctc gcgaaagcgg tctgcctgac acattgatgc tggatgtgcc
     4861 ggcgccttcg cgagcaggct cgctcccaca gaggagcgat catctgaacc tgtaccaagg
     4921 aactagaaat ctccacattg cgggcaattg ttgtccgggc ggcggcgccc aagaatctgc
     4981 accagaccgg gaaaatttcc cgggaacaac aaaaaccgca gaggaagccg tcatgactca
     5041 acccgtacgt cgccagccct tcgtcttgag catgttgctc agtgccatgc tgttgtccgg
     5101 ccaggcattg gccggggttt ccgaccagga cattctccag gaccccaaga accccgagca
     5161 gatcgtcacc aacggcctgg gcgtccaggg ccagcgctac agcccgctgg acattctcaa
     5221 cgtcgacaac gtcaaggagc tgcgaccggc gtgggcgttc tccttcggtg gcgagaagca
     5281 gcgcgggcaa caggcgcagc cgatgatcaa ggacggtgtg atgtacatga ccggctccta
     5341 ctcgcgggtg ttcgcggtgg atgcgcgcac cggcaagaaa ctctggcaat acgacgcgcg
     5401 cctgcccgat gacattcgcc cgtgctgcga cgtgatcaac cgtggcgtcg cgctgtacgg
     5461 cgacctggtg atcttcggca ccctcgacgc caagctcgtg gcgctgaaca aggacaccgg
     5521 caaggtggtc tggagcaaga aagtcgccga ccacaaggaa ggctactcga tcagcgccgc
     5581 gccgctggtg atcaacggca agctgatcac cggggtggcc ggtggcgagt tcggcgtggt
     5641 cggcaagatc gaggcctacg acccgaaaaa cggcgacctg ctgtggaccc ggccgacggt
     5701 cgaaggccac atgggctacc tgtacaagga tggcaaggcc gtggaaaacg gcatctccgg
     5761 cggcgaggcg ggcaagacct ggccggggga cctgtggaag accggcggcg cggcaccctg
     5821 gctgggtggc tactacgacc cggaaaccaa cctgttgctg ttcggcaccg gcaacccggc
     5881 gccgtggaac tcgcacctgc gcccgggcga caacctctac tcgtcgtcgc gcctggcgct
     5941 caacccggac gatggcacca tcaaatggca tttccagagc acgccccacg acggttggga
     6001 ctatgacggc gtgaacgagc tggtgtcgtt caactacagc gaaggcggca aggaaatcaa
     6061 ggcagcggcc accgccgacc gtaacggctt tttctacgtg ctggatcgca ccaacggcaa
     6121 attcatccgt ggcttcccgt ttgtcgacaa gatcacctgg gccaccggcc tggataaggc
     6181 cggccggccg atctacaacg aagccagccg ccccggcgcc ccgggttccg aagccaaggg
     6241 cagctcggtg ttcgtcgcgc cggcgttcct cggcgccaag aactggatgc cgatggccta
     6301 caaccgtgac accgggttgt tctacgtgcc gtccaacgag tggggcatgg acatctggaa
     6361 cgagggcatc gcctacaaga aaggcgcggc cttcctcggc gccgggttca ccatcaagcc
     6421 gctgaacgaa gactacatcg gcgtgctgcg ggccatcgat ccgaaaaccg gcaaggaagt
     6481 ctggcgccac aagaacttcg cgccgctgtg gggcggggtg ctgaccacca aaggcaacct
     6541 ggtgttcacc ggcacgccgg aaggcttcct gcaggcgttc aatgccaaga ccggtgaaaa
     6601 ggtctgggaa ttccagaccg gttccggcgt actgggttcg cccgtgacct gggaaatgga
     6661 cggcgagcag tacgtctcgg tgctctccgg ctggggcggc gccgtgccgc tgtggggcgg
     6721 cgaagtggcc aagcgggtga aagacttcaa ccagggcggc atgctctgga ccttcaagct
     6781 gcccaaggac ctcgtggcca agcattaatc acaccgcccc ccctgtagga gcgagcctgc
     6841 tcgcgaaggc gtcgtgtcag ccacccatag gctgaatgac acaccgcttt cgcgagcagg
     6901 ctcgctccca cagggattgt tcccacatct ggatttgtgc aaaacctacg accaaataac
     6961 gagagcccct cctgccaacg atgcattcgt ctggcgcgcg gggctctcta gtatcggttc
     7021 atcgcccgtc gacacgacag gcatcgaccc agacagaggc ccatcatgat ctacgcccaa
     7081 cccggaacac ccggcgccgt cgtttccttc aagccgcgct acggcaactt catcggcggc
     7141 gaattcgtcg cgccggtcaa tggcgaatac ttcaccaata cctcgccggt caacggcgaa
     7201 gtgatcgccg aattcccgcg ctccggcgcc gccgacatcg acaaggccct cgacgccgcc
     7261 catgccgccg ctgacgcctg gggcaagacc tcggcccagg accgctcgcg ggtgttgctg
     7321 aaaatcgccg accgcatcga acagaacctg gaaatcctcg ccgtcaccga aacctgggac
     7381 aacggcaagg cggtgcgtga aaccctcaac gccgacgtgc cgctggcggc cgaccatttc
     7441 cgctacttcg ccggttgcat ccgcgcccag gaaggcggcg ccgccgagat caacgaactg
     7501 accaccgcct accacttcca cgagccgttg ggcgtggtcg ggcagatcat tccatggaac
     7561 ttcccgctgc tgatggccgc ctggaaactc gcgccggccc tggccgcggg caactgcatc
     7621 gtgctcaagc cggccgagca gacgccgctg tcgatcatgg tcttcgccga actgattgcc
     7681 gacttgctgc cggcgggcgt gctgaacatc gtccagggtt tcggtcgcga agccggcgag
     7741 gcgctggcca ccagcaagcg catcgccaag atcgccttca ccggctcgac cccggtcggc
     7801 gcgcacatca tgcattgcgc cgccgagaac atcattccca gcaccgtgga actgggcggc
     7861 aagtcgccga acatcttctt cgaagacatc atgaacgccg aacctgcgtt catcgaaaag
     7921 gccgccgaag gcctggtgct ggcgttcttc aaccagggcg aggtgtgcac ctgtccgtcc
     7981 cgggcgttgg tgcaggagtc gatctacgag ccgttcatgg ccgaagtcat gaagaagatc
     8041 gtcaagatca agcgtggcaa cccgctcgac accgagacca tggtcggcgc ccaggcgtcg
     8101 gagcagcagt acgacaagat cctctcgtac ctgaccatcg cccaggaaga gggcgcccag
     8161 ctgctcaccg gtggcgcggc cgaacgcctg gagggcgatc tgtccagcgg ctattacatc
     8221 cagccgacgc tgctcaaggg caccaacaac atgcgcgtgt tccaggaaga aatctttggt
     8281 ccggtggtgg gcgtcaccac cttcaaggat gaggccgaag ccctggcgat tgccaacgac
     8341 accgaattcg gcctcggcgc cggcctctgg acccgcgaca tcaaccgcgc ctaccgcatg
     8401 ggccgggcga tcaaggccgg gcgcgtgtgg accaactgct accacctgta cccggcgcat
     8461 gcggcgttcg gtggctacaa gaaatccggc gtcgggcggg agaatcacaa gatgatgctc
     8521 gaccattacc agcagaccaa gaacctgctg gtgagctacg acatcaaccc gctcgggttc
     8581 ttctgatttt ctaaattcac cacaaaacaa attgtgggag cgggcttgct cgcgaaggcg
     8641 gcgtcacatt caacatatgg gttgactgac actccgcttt cgcgagcaag cccgctccca
     8701 cattggtttg agtgtctgat accccctacc aacgcacccc cgaacctcct tcgaaagtag
     8761 cattcgggca cccggcgcag cgtgcattaa tggtgctacc ggaatcgccc ggcacaagaa
     8821 gaggaatgac ccatgtggac taaacccgcg tttaccgatc tgcgcattgg cttcgaagtg
     8881 acgatgtatt tcgccaaccg ttgattgacc acccggccag ccgttgcgtt ggccgggcct
     8941 gccttctgga gcattgccca tgcacatccg cgtcctcggc tccgccgccg gtggtggttt
     9001 tccgcagtgg aactgcaact gccgccagtg cgccggcgtg cgcaacggca gcctgcgtgc
     9061 ccagcggcgc acgcagtcgt caatcgccct gagcgacaac ggcgtggact gggtgctgtg
     9121 caacgcttcg ccggacattc gcgcgcaact cgacagtttc ccgccgctgc aaccggcccg
     9181 ccgcttgcgt gatagcgcca ttgccgcagt ggtgttgatg gacagccaga tcgatcactg
     9241 caccggtctg ctgagcctgc gcgaagggtg cccgcatgat gtctggtgca ccgagcgggt
     9301 ccatcaggac ctcagcagcg gcttcccgct gttcaccatg ctcagccact ggaacggcgg
     9361 attgcagtgg caacccatag ggctcacgcg tgagccgttc tacattccga cctgcgcgca
     9421 cctgcaattt cgcgcaattc ccctggtcag caacgcaccg ccgtactcgc ccaaccgggg
     9481 ccatccgcag ccgggcgaca ccatcggcct gttcattgaa gaccagcgca gcggcgcctc
     9541 gctgttctac gcgccgggcc tggggcaggt cgacgacgaa ctgctggact ggatgcagcg
     9601 cgccgattgc ctggtgctgg acggcacgct gtggcgcgat gacgagatgc gcctgtgcga
     9661 agtcggccag agcctgggca gcgaaatggg gcatctggcg caaagcgggc ccggcggcat
     9721 gctggaagtg ctggaaggat ttcctcgcca gcgcaaggtg ctgattcaca tcaacaacac
     9781 caacccgatc ctcgacgaag actcggcgga gcgggcgctg ctggagcggc gggggatcga
     9841 ggtggcgtat gacggcatgg atattgtgtt gtagcgactg gcctcttcgc gagcaagccc
     9901 gctcccacag tggatggcgg gtgcacacaa aacccagtgg gagcgggctt gctcgcgaag
     9961 gggccagacc cgacacagca gagcttccag gagaacaatc atgacaatga cccccgccga
    10021 attcgagcag gccctgcgcg ccaagggcgc ctactaccac atccatcacc cgttccacca
    10081 agccatgtac gccgggcagg ccacccgcga gcagatccag ggctgggttg ccaatcgctt
    10141 ctactaccag gtcaacatcc cgctcaagga cgccgccatc cttgccaact gcccggaccg
    10201 cgatgtgcgc cgggaatggc tgcaacgcat cctcgatcac gacggcgccc ccggcagcga
    10261 aggcggcatc gaagcctggc tgcgcctggg cgaagcggtg gggctggatc gcgagcaaat
    10321 actgtcgcaa gagctggtgc tgcccggcgt ccgtttcgcc gtggacgcct acgtcaattt
    10381 cgcccggcgt gcctgctggc aggaagcggc cagcagctcg ctgaccgaac tgttcgcgcc
    10441 gcagatccat caatcgcggc tcgacgcgtg gccgacccat tacccgtgga tcgacgtcgc
    10501 cggctacgac tacttccgca cgcggttggg ccaggcccgg cgcgatgtcg agcacggctt
    10561 gcgcatcacc ctggcgcact acgtcaccct tgaggcccag caacgcatgc tcgagatcct
    10621 gcaattcaag ctggatgtgc tgtggagcat gctcgacgcc atgagcatgg cctacgagct
    10681 ggagcgcccg ccgtatcaca ccgtcacccg tgacaacgtc tggcatcggg ggattgccct
    10741 gtgagcctga tcgaccgcga gctgtcaccg tcgttgcgcc ggggttttcg tctgcaatgg
    10801 gaaccgcgcc aggactgtca cgtgctgctg taccccgaag gcatgatcaa gctcaacgcc
    10861 agtgccgcgc agattctcga actgctggac ggccagcgca gcgtcgcggc gatcattgac
    10921 cggctgacgg cggatttccc cggcgtgccg gggattgacg aggatgtgct ggcgttcctg
    10981 gaggtggccc atgcgcaatt ctggatcgag tgaagcgctg ccggggccgc cgttgtggct
    11041 gctggcggag ctgacctacc gctgcccgct gcaatgcccg tattgctcca atccgctgga
    11101 cttcgcccga cacggcgagg aactgggcac cgaagagtgg attcgggtct tccgcgaggc
    11161 gcgggagatg ggcgccgccc aactgggctt ttccggtggc gaaccgctgg tgcgccagga
    11221 cctggccgag ctgatcaagg ccgcgcgggg catgggctac tacaccaacc tgatcacctc
    11281 gggcatcggc ctgaccgagc agaaggtgcg cgatttcaag gatgccgggc tcgatcatat
    11341 ccagatcagt ttccaggccg ccgacgaggc ggtgaacaac atgctggccg gctcgcgcaa
    11401 ggccttcgcg cagaaactcg ccatggcccg ggcggtgaaa gcccagggct acccgatggt
    11461 gctgaacttc gtcacccacc ggcacaacat cgaccgcatc gaccggatca ttgacctgtg
    11521 cctggagctg gaggcggatt tcgtcgagtt ggccacctgc cagttctatg gctgggccga
    11581 gctcaaccgc gtcggtctgc tgccgacccg tgagcaattg caacgcgccg agcgcatcac
    11641 caacgagtac cgtgagcgac tggaggacca ggggcacccg tgcaagctga tcttcgtcac
    11701 cccggactac tacgaggaac gccccaagac ctgcatgaac ggctgggcca acctgtttct
    11761 cgacatcacc cccgacggca cggcgttgcc ttgccatagc gcccggcaat tgccggtgca
    11821 gtttcccaac gtgcgtgaac acagcatttc gcacatctgg aacgattcgt tcggcttcaa
    11881 ccgctttcgc ggcgatgcgt ggatgaagga gccgtgtcgc tcctgcgatg agaagcacaa
    11941 ggacctgggc ggctgccgct gccaggcctt catgctgacc ggcgatgccg agaacgccga
    12001 cccggtgtgc agcaaatcgc cgcaccatgg ggtgatcctc aaggcgcggg aggaggccga
    12061 ggcgccgggg ctgggcatgg aacacctgac gctgcgcaac gagaaggctt cgcggctgat
    12121 ctaccgcggc tagatcaaac accgcaaatc ccttgtggga gcgggcttgc tcgcgaaagc
    12181 ggtgtgtcag cgagagaatc tgccgactga cgcaccgctt tcgcgagcaa gcccgctccc
    12241 acaggggatc tacggtgagt ccagccattg gtctgattgc attcagcgcc ggatgcgtta
    12301 gtgtggctgt tacattccaa aacaataaaa aacaggcttt ccaatgagcc agagtctcag
    12361 ccaactgcgt aaattcgtct cgcctgaaat catcttcggt gccggctgcc ggcacaacgt
    12421 cggcaactac gccaagacct ttggtgcgcg caaggtgctg gtggtcagcg atccgggggt
    12481 gattgccgcc ggttgggtgg cggatgtcga ggccagcctg caagcgctgg gcatcgagta
    12541 ctgcctttac agcgccgtct cgcccaaccc ccgggttgaa gaagtcatgc tcggtgccga
    12601 gctgtaccgg gaaaaccact gcgatgtgat cgtcgctgtc ggcggtggca gcccgatgga
    12661 ttgcggcaaa ggcatcggca ttgtcgtcgc ccatggccgc agcatcctcg aattcgaagg
    12721 ggtggacacc atccgcgtgc ccagcccgcc gttgatcctg attccgacca ccgccggcac
    12781 ttcggccgat gtctcgcaat tcgtgatcat ctccaatcag caggaacgca tgaagttctc
    12841 catcgtcagc aaggcggtgg tgccggacgt ctcgctgatc gacccggaaa ccaccctgag
    12901 catggacccg tttctttcgg cctgtaccgg catcgatgcc ctggtgcacg ccatcgaagc
    12961 cttcgtgtcc accggtcacg ggcccctgac cgatccccat gcgctggagg cgatgcgcct
    13021 gatcaatggc aacctggtgc agatgatcgc caacccgacg gacatcgccc tgcgcgaaaa
    13081 aatcatgctc ggcagcatgc aggccgggct ggcgttctcc aacgcgatcc tcggcgcggt
    13141 gcatgcgatg tcccacagcc tgggcggttt tctcgacttg ccccacggcc tgtgcaacgc
    13201 ggtgctggtg gagcacgtcg tggcgttcaa ctacagctcg gcgccggagc gtttcaaagt
    13261 gatcgccgag accttcggta tcgattgccg gggtctcaac cagcggcaaa tctgcgggcg
    13321 cctggtggaa cacctgatcg ccctgaaaca tgcgatcggc ttccacgaaa ccctcggctt
    13381 gcatggggtc aggacctctg acattccgtt cctgtcgcag cacgccatgg atgacccgtg
    13441 catcctgacc aacccgcgcg agtccagcca gcgtgacgtc gaggtcgtct atggcgaagc
    13501 cctctgacga acaacaacgg gccctggccg ggctgctggg actgggcagc cactcggcgc
    13561 gcaagagtca ttacccggaa ctggcggcgc gcctggatga gctggaggcg gagcggaacc
    13621 gctacaaatg gctgttcgaa aacgccgtcc acgggatctt ccaggccagc ctgcacgagg
    13681 gcctgcgcgc cgcgaatccg gcactggcgc acatgctcgg ctaccaggac ccgcaggagg
    13741 tgctgttttc cctgaatgac ctggccagcc acctgttcgc cggtggggcg caggaactgg
    13801 aaaccattgg cgacctcctc aagcggcaac gcagcctgca cggctacgaa acccgcttgc
    13861 gccgcaagga cggcagccac ctcgacgtgt tgatgaacct gttgctcaag cccggccagg
    13921 aagggctggt ggaagggttc gtcgccgata tcacagagcg cgtgcaggct cagcagcgcc
    13981 tgcaacaact caatgacgaa ctggagcagc gcgtcgctgc gcgcaccgat gaactgctgg
    14041 aagccaaccg caacctgcag cagcagatca cccagcgtaa acagatcgcc caggccctgc
    14101 gcgatgcccg tgatgccgcc gaagccgcca accgcagcaa ggacaagtac ctggcggcgg
    14161 ccagccatga cctgctgcaa ccgctgaacg ccgcgcgctt gctgatctcg accctgcgcg
    14221 agcggcagtt gccggaggtg gagcaggtgc tggtcgagcg cacgcaccag gcgctggaag
    14281 gggctgaaga cctgctcacc gatctgctgg acatttcccg gctcgaccag gcggcggtca
    14341 agccggacat tgcactttac cgcctggatg agttgctcgg cccgctggtc tcggagttcc
    14401 agtccgttgc ccaggcggcg ggcttgaacc tgcgggtgca cacgggcgat tacgccatca
    14461 gcaccgactt gcgcctgatg acacgcattc tgcgcaactt tctcagcaat gcctgccgct
    14521 ataccgacga gggcagcatc ctgctcggcg cccgacggcg gggcgagtat ttgcgtctgg
    14581 aggtgtggga caccgggcgc gggatcgcgg cggaccggct cgactcgatc ttcctcgaat
    14641 tcaatcaact ggatgtcggc cgcgccgccg accgcaaggg cgtgggcctg gggctggcga
    14701 ttgtcgagcg catcgcccgg atcctcggtt accccatcgg cgtgcattcg ctgccggggc
    14761 gcggttcgat gttcagcatc gatgtgccgc tgtcccatga catcccgttg ccgatcgacc
    14821 aggctgcgcc ccagcccgtc accggtaacc cgttgccggg ccgacgtttg ctggtgctgg
    14881 acaatgaatt gagcattctt gaaagcatga gcgcgttgct cggccagtgg ggctgcgaag
    14941 tcgtcacggc caccgacgaa gcctcggccc tggcggcgct ggccggacgg gcaccggaac
    15001 tgattctggc ggactaccac ctcgatcacg cggtggttgg ctgcgatgtg gtgcgccatc
    15061 tgcgcgagca tttccaccag cgtatccccg cggtgatcat caccgccgat cgcaccgacc
    15121 agtgccggcg ctcgctgcaa cgtctggagg cgccactgct gaacaaaccg gtgaagcctg
    15181 gcaagttgcg cgcggtgttg agtcagctgt tggcggcgcc ggcctgaagc gcccggtagc
    15241 gcaggctgaa acccagttcc gtggactggc cttgctccag tagtcgcaag cccggccgac
    15301 ccggcaagtg gtgcgcgttg accgggtggc tgaccggttc caggcagaaa aaatccaggc
    15361 caggcgggca gtagagcagg tagtagtcgc taccgctggc ctggcactcc agttcgtaac
    15421 ccaggtcagg ttgccggatc aggcagtggc cgttccattg gcaaaagccg ttatcgacca
    15481 gcgtctcggg caatgcttgc agctgccgga aatcccatgg cgcgggtacg ctggcaagcc
    15541 cggtcggcaa tctggacgcc tcacacaacc agacctgttc ggcgtgtgcc tgcaggcgag
    15601 tgctggccag gcgcggaaaa taggggtgca ggccgagccc atgccaggcc gggcgggcgg
    15661 ccagatgagt gacttgcagc tcaatgccca ggcggccctg gctcaggtgc aagcgttgcc
    15721 gggcgcgata agcgaagggc gtggtgctgt cgagttgcag cacgacttca tcgtggcggt
    15781 gcgaaaccac ctgccacgct tgttgccagg ccgtgccgtg gatcggcagc ggatcgccgg
    15841 ggctgttggg cgtcagcgcc agccagccat cggggcagtc gaagccgcct tcggcgatgc
    15901 gattggacca gggcgccagg ggaaaacagc cgagcttgcc gggcaggccg ctgtgcagcg
    15961 ccggcgcgtc ggtgtgacgc agcaggggtt ggccggtgct gcgcacgctc cagttgacga
    16021 tgctcgcgcc gagttcgggg gcgagggtga ggcgggtgta ttcgtcttcg agttcaatca
    16081 gtttcattgt gattgtcttg gtgaagtgat gggttcatgg ctgcggccct gtcgcggcga
    16141 gcagtgcgga tgctagtctt gtttaacgct gttgtcaggg agccctcatg ggcaatcaca
    16201 agatcgagat ccgtcgcagt aacgtcgaga aaattctgct gggtgccgag aaggtcttcg
    16261 ccgaaaaagg ctttggcagc accgccatgg ccgacatcgc cgccgaggtg caactgccgc
    16321 gctccaatct gcattactac ttcagtacca agaccgagtt gtacagcgcg gtgctgttcg
    16381 acctgctgga agtgtggaag caggacgcgc tgtgcttcga gatgttcgac gacccgcgcg
    16441 tggtgctcag cagctacatc cgcgccaaga tgaaccactc ccgcagccgg ccctacggtt
    16501 ccaaagtctg ggccaacgaa atcatccacg gcgcgccgac cctgggcgag gcgctggatg
    16561 ccagcctgta cgactgggcc aagatgaagg aagcgaagat ccgccagtgg gtggacgaca
    16621 aacgcatcct gccggtggag ccgtcgagcc tgctgtacat gatctgggcc tcgacccagc
    16681 actacgccga ctttgaccat caggtgaata ttctgaatga ccatcagccg ctgtcggaca
    16741 tgcagttcga gcgggcggtg caaacggtca cgagtgtgat tttgcggggg atcgggttgg
    16801 agccttgaat caaaagatcg cagcctcgtt tcactcgaca gctcctacag gcgttcacat
    16861 tcccttgtag gagctgtcga gtgaaacgag gctgcgatct cttgatagtt aacgatcaaa
    16921 cggcaacgtg atacggattc ctcggatcat gattccagtc caggaacggc ttcccggtct
    16981 ccaccggcac catctcgatg caatcctgca ccgggcaggt gatctggcac aggttgcagc
    17041 ctacgcattc ctcatcgatc acctcgtacg catgcgtacc atcggccttt ttcaggctgg
    17101 ccaccgcctg gtgcgaggtg tcttcgcagg cgatgtgaca gcggccgcaa ccgatgcagg
    17161 cctcctggtc aatcttcgcg atcacttgat agttgatgtc caggtacttc cagtcggtgg
    17221 tattggccac cgcgcgcccg gaaaattctg aaatgctggc gtagccctga ctgtccatcc
    17281 agcgcgacaa cccgtccttc atctcctcga caatccggaa gccatgcagc atggccgccg
    17341 tgcacacctg caccgagccg ctgcccaggg cgatgaattc cgcggcgtcg cgccagttgc
    17401 cgatgccgcc gatgccgctg atgggcagtc cttgggtctg cgggtcgcgg gcgatttcgg
    17461 cgaccatgtt cagggcaatc ggcttgaccg ccgaaccgca gtagccgcca tgggtgctct
    17521 ggctgccaac cacgggattg gcgaccatgc gctccaggtt gacgctggtg atcgagttga
    17581 tggtgttgat cagcgacacc gcatcggcac cgccccggtg cgccgcacgg gcggcgacgc
    17641 ggatgtcggt gatgtttggc gtgagcttga cgattaccgg cagcgaacaa taggtcttgc
    17701 accagcgggt gacctgttcg acgtactccg gcacctggcc gaccgccgcg cccatgccgc
    17761 gttccggcat gccgtggggg cagccgaaat tcagttcgat gccgtcggcg ccggtggctt
    17821 cgaccagcgg caggatgtgt ttccaggact cttcgacgca gggcaccatc aacgacacga
    17881 tcaaggcgcg gtccggccag tccttcttca cctgggtgat ttcccgcagg ttgatctcca
    17941 gcgagcggtc ggtgatcaat tcgatgttat tgaaacccag cacttcacga ttcgccccga
    18001 agtgcgcgga gtaacgcgac gacacgttga ccgccgccgg gtcttcaccc agggttttcc
    18061 agaccacgcc gccccagccg gcctcgaagg cgcggaccac gttgtaggcc ttgtcggtcg
    18121 gcggcgcgga ggccagccag aatgggttgg gggacttgat gccagcgaag acaatcgaca
    18181 gatcggccat ttacgcagcc tccacattga gcatcagttg agcatggatg gcctcggcgg
    18241 cgcgtttgcc gtgctgcacc gcctgcacgg tgaggtcctg gtcgaggctg gtgcagtcac
    18301 cgccggcata cacgccgggg atgctggtgc gcagttgttc gtccacctga atgcgatcgc
    18361 cctggcgctt gagttcgcgg gccagcgggt cggcgagggc gcttgagtcg aaggtttggc
    18421 cgatggcctt gaagatcgca tcggcggcca gttcgaaggt ttcgccagtg gtttgcagcc
    18481 ggccttcgac gagatgggtg cgggcgaagc gcatgccacg cacgttgccc tggtcatcga
    18541 gcaacacgtc ttccggttgc gcccaggtca acaggcgcac ctgattggcc ttggcgatgt
    18601 cctgttcgtg gtgggtcgcc cccatgtctt cgacgccacg gcggtacacc aggttgacgt
    18661 catgggcacc gaggcgggcc atttgcaccg ccatgtcgat cgcggtattg ccggcgccta
    18721 gcacgatgca gtggtcagcc agtggcaact gggtcaggtc gtcggcctgg cgcagttcac
    18781 ggatgtaatc ggtggcggcg acgaggccgg gcgcgtcttc atgcagcaga ccaagctgct
    18841 tgctggcagc caggccgagg ccgaggaaca ccgcatcgaa ctgttgatgc agctcgctca
    18901 ggctcaggtt ttccccgagt ttttgcccat ggcggatttc aatgccgccg atctccagca
    18961 ggaagtccag ttccttctgc gcgtaatcgt ccaccagctt gtacttggcg atgccgtatt
    19021 cattcaggcc gccggctttt tccctggctt cgaaaatcac cacgtcatgg ccgtgcatgg
    19081 cgctgcgatg ggcgcaggac agcccggccg ggccggcacc gaccacggca atgcgcttgc
    19141 cggtggcggc ggcgcgggag aacgggtgtt ggctgaaatg ggcgttgtcc acggcgtagc
    19201 gctgcaacaa accgatgagc accggtgcgc attcatgggc gttattacgc acgcaggctt
    19261 gctggcagag gatttccgtc gggcagaccc gggcgcaact gccgccgagg atgttcgccg
    19321 agaggatttt ctgcgccgcg ccctgaacgt tgtcctggtg gatgttgcgg atgaacgagg
    19381 ggatgtcgat ttcgctgggg caggcattca cgcacggcgc gtcgtagcaa tacaggcagc
    19441 gcgaggcttc caggtgggcc tggcggtcgt tgagtggcgg cgcgaggtcc gtgaagtggc
    19501 cggcgagggc ggccgcgttc tcgtagggat gcgggagatg ggtcagggtc ttgatcacgg
    19561 tcttggcctc acggtgatgg aggttatgcc tctggtgggc attgagtttt ttgttgtctg
    19621 ggcgggcctc ttcgcgagca agcccgctcc cacatctgga atgcgtaacc ctgtgggagc
    19681 gggcttgctc gcgaaggccg aaggcctcga tctcagcgct tcacggcaac cggctgattc
    19741 aactcggccc gcttgctcag taaatcaaac accgccggat atgccggccg ttcgatgtac
    19801 cgcccggcgc cgcgctcggc gcgcaggtcg ccgtcggccc agaccacccg gccctggctg
    19861 atggtgtggc tgggcacgcc gcgcacggtc ttgccttcga agatgttgaa gtcgacctgc
    19921 tggtgatggg tcttggccga aatcgtgcgc gtgccttgcg ggtcccacag caccaagtcg
    19981 gcatcggcgc ccacgcggat cgcgcctttg cgtgggtaaa ggttgaagat cttcgcggtg
    20041 ttggtcgagg tcagggcgac gaactgctgc atcgaaaaac gcccggtgtt caccccttca
    20101 tcccagagca ctgccatgcg gtcttcgatg ccggcggtgc cattggggat cttgctgaaa
    20161 tcgtccttgc ccgccgcttt ctgctcggcg cagaagcagc agtgatcggt ggcggtggtg
    20221 tgcaggttgc cggcttgcag gccgtgccag agcgcttcct gatggccgcg cggacggaac
    20281 ggcgggctca taacgtaacc ggcggcggtc tgccagtccg ggtgttgata gacgctgtcg
    20341 tccagcagca gatgcccggc cagcacctcg ccgtagaccg gctggccctt ggcccgggca
    20401 taggtgattt cgtccagggc ttccttggtc gagacgtgca ccaggtacag cggcgtgccg
    20461 agggtttcgg caatgcggat cgcccggctt gcggcttcgc cttcgacctg ggaaggacgc
    20521 gacagcggat gcgcctccgg cccggtcatg ccctgggcca tcagtttgcg ttgcaggtgg
    20581 tagaccagct cgccgttttc cgcgtgcacg gtgggcaccg cgcccagttc caggcagcgc
    20641 tcgaaactcg ccaccagggt gtcgtccgcc gccatgatcg cgtttttgta agccatgaaa
    20701 tgcttgaagc tgttgacccc gtgatggctc accagctcgg ccatttcctc gcgcacctgt
    20761 tcgctccacc aggtgatggc gacgtggaag ccgtaatcgg aggcagactt ctcggcccag
    20821 ccacgccatt gatggaaggc ttccatcagc gactgctgcg gattgggtat gacgaagtcg
    20881 atgatcgagg tcgtgccacc ggccagaccc gccgccgtgc cgctgaaaaa gtcttcgctg
    20941 gccacggtgc ccatgaaggg cagttgcata tgggtgtgcg gatcgatgcc accgggcatc
    21001 aggtactggc cgctgccgtc gaggacctcg gcgcctgcgg gaaggtcgag gttttcgccg
    21061 attgccttga tcacgccgtc tgcgcaatac acatcggcgc gataactttc atcatgggta
    21121 acaacggtag cgccacggat caacagagac attccggatt cctcgcaggc atgaccggct
    21181 gatgccggtt ctaggtgttt tatatgaagc catcgtcaac aggcatattc ctgtcagcgc
    21241 tgtcaggaat aaacgctagc tgcacttacg ggaatcagca agaatatttt ttataagctt
    21301 atatctgttt taagttattg ataattaacg atgtaaatcg aaaatcacca aaatggtgag
    21361 ggtcctcacc attttgacgc acttgacagg atcgaaatat ggtcaagatt tcctatgtga
    21421 aatcagctgt ttgtgcgtgg tctatggttg atgcgcaatg gtgaaaaaaa gatccacgca
    21481 ccacattgag tcctgacgat ccggacaact tgcctgtcat tcggcctgag tgagagggca
    21541 aaaaagccgg ggattcaata gttgtcttca taaaactgat taatatcagt tgcttaaaaa
    21601 gtgtttatgg aactgcccga tgcgcaagcg gggcgcccgg cacgcttatt gaagtcgcca
    21661 gcccctgatg agcaaaaata actcgaagaa cagtggagcg gccatgcaac agatcagatc
    21721 gcaagtgacc gagcgcgacg gcttgtttga gctggaagcc ggcagcgatg tcctcgacag
    21781 tccccgttac aaccacgaca tggcaccgac caaggtgcgc gaacgaacct ggaacaaatg
    21841 gcacatcacc gccttgtggg tcggcatgtc gatctgcgtg ccgacctaca ccctcggcgg
    21901 cgtcctgacg gcgtatttcg gcctgagcgt cggcgaagcg ctgctggcga tcctgtttgc
    21961 caacctcatc gttttgatcc cgctgaccct gaacgccttt cccggcacca agtacggcat
    22021 tccgttcccg gtgttgctgc gctcgtcgtt cggcatcctc ggttccaacg tcccgtgcct
    22081 gatccgcgcc ctggtggcgt gcggctggtt cggtatccag acgatgttcg gcg
//
