LOCUS       NZ_CABVIY010000001     23277 bp    DNA     linear   CON 07-NOV-2023
DEFINITION  Pseudomonas fluorescens isolate PS918, whole genome shotgun
            sequence.
ACCESSION   NZ_CABVIY010000001
VERSION     NZ_CABVIY010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Pseudomonas fluorescens
  ORGANISM  Pseudomonas fluorescens
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
REFERENCE   1
  AUTHORS   Chandra,G. and Truman W,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2019) JOHN INNES CENTRE, NORWICH, UK., Molecular
            Microbiology, Norwich Research Park, Norwich NR4 7UH, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/07/2023 08:57:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,059
            CDSs (total)                      :: 5,986
            Genes (coding)                    :: 5,920
            CDSs (with protein)               :: 5,920
            Genes (RNA)                       :: 73
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 7 of 66
            Pseudo Genes (incomplete)         :: 63 of 66
            Pseudo Genes (internal stop)      :: 6 of 66
            Pseudo Genes (multiple problems)  :: 8 of 66
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:35:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 243154
            Orig. end                         :: 266431
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CABVIY010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23277
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="2"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..23277
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23277
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:13277]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13277
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            774..2384
                     /locus_tag="F8N66_RS01085"
                     /old_locus_tag="PS918_00204"
     CDS             774..2384
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1274: gamma-glutamyltranspeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015884887.1"
                     /locus_tag="F8N66_RS01085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00204"
                     /product="gamma-glutamyltransferase family protein"
                     /protein_id="WP_150768418.1"
                     /transl_table=11
                     /translation="MFKFSAHEYPYASQRQSVFAKRGMVAASQPLAAEAGIEIMRRGGN
                     AIDAAIATAAALTVVEPTGCGIGGDAFALVWTQNKLHGLNANGAAPQALSIDAVKAAGH
                     EKMPLHGWTPVTVPGCPSAWAELSTRFGRLPFADVLQPAINLARDGFPVSPVVALQWQT
                     ALEDFTPDRSEVLESWFETFLIDGRAPRAGELFRNPAQARTLSELAATGCESFYRGALA
                     QRLDAHSRATGGYLRASDLKDYRAQWVEPIKVNYRGVDVWEIPPSGQGLVALMTLKILE
                     GFDFDHRDSQQTWHRQLEAMKLAYCDGLHYITDPAHMRVAVDDLLSDHYAAHRRGQIGE
                     RAVAPQPGDPHASGTVYLATADGEGNMVSFIQSNYHGFGSGVVLPDSGIALQNRGEEFS
                     LDPGHSNCLAPGKKTFHTIIPGFLSKDGEAMGPFGVMGGYMQPQGHVQMVMNLVDFGLN
                     PQAALDAPRWQWLGGLKVGIEQDASRDLAAALARRGHAVEVACDVTSYGRGQIILRDPE
                     TGVLCGGTEPRTDSHIAVY"
     gene            complement(2884..3225)
                     /locus_tag="F8N66_RS01090"
                     /old_locus_tag="PS918_00205"
     CDS             complement(2884..3225)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007999522.1"
                     /locus_tag="F8N66_RS01090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00205"
                     /product="DUF3077 domain-containing protein"
                     /protein_id="WP_150768419.1"
                     /transl_table=11
                     /translation="MTQPANELPDIPIDTSLTSPQGSAAAQRALDYYLKPVVSEEEVGA
                     RFFDVNRNISSEEALVHASDLLRCAAATAYESASHLHGTNRDLAFSAVHMIDMAKAMVD
                     RSLERHQNG"
     gene            3356..3994
                     /locus_tag="F8N66_RS01095"
                     /old_locus_tag="PS918_00206"
     CDS             3356..3994
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019580039.1"
                     /locus_tag="F8N66_RS01095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00206"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_150768420.1"
                     /transl_table=11
                     /translation="MDKWIELVKTKMSELKVTQEILAERLGMSQGGVGHWLTKRRQPGI
                     DDMNRVLQALGLGFLEVALVIREPQDAQDEELSLTQKYNPYFRYPVSDWRETSEVRDGE
                     QGQYRFELSDYHAQGAAFWLTVVGDAMTAPSGLSIAEGMLILVDPDVEVEPGKLVIAQW
                     ANSSEAMFRKLIEEGGQRYLVPLNPTYPKALYTEECRIIGVVVQATVKF"
     misc_feature    complement(3373..3388)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.35"
                     /tool="antismash"
     gene            complement(4034..5989)
                     /locus_tag="F8N66_RS01100"
                     /old_locus_tag="PS918_00207"
     CDS             complement(4034..5989)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007981007.1"
                     /locus_tag="F8N66_RS01100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00207"
                     /product="acetyl/propionyl/methylcrotonyl-CoA carboxylase
                     subunit alpha"
                     /protein_id="WP_150768421.1"
                     /sec_met_domain="ATP-grasp (E-value: 1.2e-10, bitscore:
                     37.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.5e-13,
                     bitscore: 46.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPVLTTLLVANRGEIACRVMRTAKALGLTTVAVHSATDRDARH
                     SREADIRVDLGGSKAADSYLQIDKLIAAAKASGAQAIHPGYGFLSENAGFARAIEAAGL
                     IFLGPPASAIDAMGSKSAAKALMETAGVPLVPGYHGEAQDLDTFRDACERIGYPVLLKA
                     TAGGGGKGMKVVEDVSQLAEALASAQREAQSSFGDSRMLVEKYLLKPRHVEIQVFADQH
                     GHCLYLNERDCSIQRRHQKVVEEAPAPGLSPELRRAMGEAAVRSAQAIGYVGAGTVEFL
                     LDARGEFFFMEMNTRLQVEHPVTEAITGLDLVAWQIRVARGEALPMTQDQVPLIGHAIE
                     VRLYAEDPGNDFLPATGRLDLYRESAPGAGRRVDSGVEEGDEISPFYDPMLGKLIAWGE
                     DREQARLRLLSMLDEFAIGGLKTNINFLRRIIAHPAFAAAELDTGFIPRYQEQLLPAPS
                     DLSDEFWQAAAQAFAQSQHRAPRSDDSSSPWAVGNGFRAGLPAQITLHLSCEGQDRALT
                     LGAPDSHGAQLKGEHLLTEHDGVRRQHRAIRRGEFVYLQWEGELRRIEPYDPISAVEAS
                     HSHHGGLAAPMNGSIVRVLVEAGQTVEAGAQLVVLEAMKMEHSIRAPHAGVIKALYCQE
                     GEMVSEGSALVELEEA"
     gene            complement(5989..6804)
                     /locus_tag="F8N66_RS01105"
                     /old_locus_tag="PS918_00208"
     CDS             complement(5989..6804)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (15-256). E-value: 3.8e-43. Score:
                     139.5. Matches aSDomain:
                     nrpspksdomains_F8N66_RS01105_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010458779.1"
                     /locus_tag="F8N66_RS01105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00208"
                     /product="gamma-carboxygeranoyl-CoA hydratase"
                     /protein_id="WP_150768422.1"
                     /transl_table=11
                     /translation="MSDFNTLELLTDPRGFATLWLSREEKNNAFNAEMIRELIIALDHV
                     SSDASLRFLLVRGRGKHFSAGADLAWMQQSAELDYHTNLDDARELAELMYNLAKLKLPT
                     LAVVQGAAFGGALGLISCCDMAIGVDDAQFCLSEVRIGLAPAVISPFVVQAIGERATRR
                     YALTAERFDGQRARELGLLSESYPSSELEQRVEQWIDNLLLNSPAAMRASKDLLREVGD
                     GSLLPALRRYTENAIARIRVSPEGQEGLRAFLQKRAPSWQAAITPKESR"
     aSDomain        complement(6037..6759)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F8N66_RS01105_ECH.1"
                     /evalue="3.80E-43"
                     /label="F8N66_RS01105_ECH.1"
                     /locus_tag="F8N66_RS01105"
                     /protein_end="256"
                     /protein_start="15"
                     /score="139.5"
                     /tool="antismash"
                     /translation="FATLWLSREEKNNAFNAEMIRELIIALDHVSSDASLRFLLVRGRG
                     KHFSAGADLAWMQQSAELDYHTNLDDARELAELMYNLAKLKLPTLAVVQGAAFGGALGL
                     ISCCDMAIGVDDAQFCLSEVRIGLAPAVISPFVVQAIGERATRRYALTAERFDGQRARE
                     LGLLSESYPSSELEQRVEQWIDNLLLNSPAAMRASKDLLREVGDGSLLPALRRYTENAI
                     ARIRVSPEGQEGLRAFLQK"
     misc_feature    complement(6912..6928)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.37"
                     /tool="antismash"
     gene            complement(6923..8530)
                     /locus_tag="F8N66_RS01110"
                     /old_locus_tag="PS918_00209"
     CDS             complement(6923..8530)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_250704.1"
                     /locus_tag="F8N66_RS01110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00209"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_150768423.1"
                     /transl_table=11
                     /translation="MATLHTQLNPRSAEFAANSAAMLKQVDALHTLLAQVAQGGGPKAQ
                     ERHTSRGKLLPRERINRLLDPGSPFLEISQLAAYEVYGEDVPAAGVIAGIGRVEGVECM
                     IVANDATVKGGSYYPLTVKKHLRAQTIAQQNRLPCIYLVDSGGANLPRQDEVFPDREHF
                     GRIFFNQANMSALGIPQIAVVMGSCTAGGAYVPAMADEAIMVREQATIFLAGPPLVKAA
                     TGEVVSAEDLGGADVHCKISGVADHYAESDEHALAIARRSVANLNWRKLGEVQQRTPIA
                     PLYSSDELYGVVPADAKQPFDVREVIARLVDGSVFDEFKALFGTTLVCGFAYLHVYPIA
                     ILANNGILFAEAAQKGAHFIELACQRGIPLLFLQNITGFMVGQKYEAGGIAKHGAKLVT
                     AVACAKVPKFTVIIGGSFGAGNYGMCGRAYDPRFLWMWPNARIGVMGAEQAAGVLVQVK
                     REQAERSGQGFSAEQEAEIKQPILDQYEEQGHPYYSSARLWDDGVIDPAQTRDVLGLAL
                     SASLNAPIEPSRFGVFRM"
     gene            complement(8542..9705)
                     /locus_tag="F8N66_RS01115"
                     /old_locus_tag="PS918_00210"
     CDS             complement(8542..9705)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_250705.1"
                     /locus_tag="F8N66_RS01115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00210"
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="WP_077045893.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.8e-39, bitscore:
                     130.3, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 8.9e-29, bitscore:
                     95.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.5e-42, bitscore:
                     140.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYPSLNFALGETIDMLRDQVQSFVAKEIAPRAAQIDIDNLFPAD
                     LWRKFGDMGLLGITVPEEYGGAGLGYLAHVVAMEEISRGSASVALSYGAHSNLCVNQIN
                     RNGNHEQKLKYLPKLISGEHIGALAMSEPNAGSDVVSMKLRADKRGDKYVLNGSKTWIT
                     NGPDANTYVIYAKTDLEKGPHGITAFIVERDWKGFSRSNKFDKLGMRGSNTCELFFDDV
                     EVPEENILGVLNGGVKVLMSGLDYERVVLSGGPTGIMQACMDLIVPYIHDRKQFGQSIG
                     EFQLIQGKVADMYTQLNASRAYLYAVAQACERGETTRKDAAGVILYSAERATQMALDAI
                     QILGGNGYINEFPAGRLLRDAKLYEIGAGTSEIRRMLIGRELFNETR"
     misc_feature    9780..9798
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
     gene            10001..11698
                     /locus_tag="F8N66_RS01125"
                     /old_locus_tag="PS918_00211"
     CDS             10001..11698
                     /NRPS_PKS="Domain: AMP-binding (29-462). E-value: 2.8e-99.
                     Score: 324.4. Matches aSDomain:
                     nrpspksdomains_F8N66_RS01125_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007992803.1"
                     /locus_tag="F8N66_RS01125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00211"
                     /product="AMP-binding protein"
                     /protein_id="WP_150768425.1"
                     /sec_met_domain="AMP-binding (E-value: 4.2e-107, bitscore:
                     354.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQPSASPQRSYTRGSQDKALLAMTIGQAFENTVAQYPDGEALVV
                     RHQQLRYTWRQLAHAADLHARALLALGLQAGDRLGIWAPNCAQWCITQIATAKIGVILV
                     NINPAYRSSELEYVLKQSGCQWLVCAGAFKTSNYHAMLQGLVPELAEQPVGKLHSERLP
                     ELRGVISLDAQPPGGFVPWAQLADLAGSVSDQQLHERQESLHFDQAVNIQYTSGTTGFP
                     KGATLSHYNILNNGYMVGESLGLTAADRLVIPVPLYHCFGMVMGNLGCITHGSTMIYPN
                     DAFDPLLTLNTVAEEKATALYGVPTMFIAMLDQPQRAEFDLSSLRTGIMAGATCPIEVM
                     RRVINEMHMSEVQIAYGMTETSPVSLQTGPSDDLELRVTTVGRTQPQLESKIIDEAGNL
                     VPRGTIGELCTRGYSVMLGYWNNPQGTAEAIDQAGWMHTGDLASMNDEGYVCIAGRNKD
                     MIIRGGENIYPRELEEFFFTHPAVADVQVIGIPCSRYGEEIVAWIKFHPGHSASEQELQ
                     AWCKERIAHFKTPRYFKFVEEFPMTVTGKIQKFKMREISIEELRINKA"
     aSDomain        10088..11386
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F8N66_RS01125_AMP-binding.1"
                     /evalue="2.80E-99"
                     /label="F8N66_RS01125_AMP-binding.1"
                     /locus_tag="F8N66_RS01125"
                     /protein_end="462"
                     /protein_start="29"
                     /score="324.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FENTVAQYPDGEALVVRHQQLRYTWRQLAHAADLHARALLALGLQ
                     AGDRLGIWAPNCAQWCITQIATAKIGVILVNINPAYRSSELEYVLKQSGCQWLVCAGAF
                     KTSNYHAMLQGLVPELAEQPVGKLHSERLPELRGVISLDAQPPGGFVPWAQLADLAGSV
                     SDQQLHERQESLHFDQAVNIQYTSGTTGFPKGATLSHYNILNNGYMVGESLGLTAADRL
                     VIPVPLYHCFGMVMGNLGCITHGSTMIYPNDAFDPLLTLNTVAEEKATALYGVPTMFIA
                     MLDQPQRAEFDLSSLRTGIMAGATCPIEVMRRVINEMHMSEVQIAYGMTETSPVSLQTG
                     PSDDLELRVTTVGRTQPQLESKIIDEAGNLVPRGTIGELCTRGYSVMLGYWNNPQGTAE
                     AIDQAGWMHTGDLASMNDEGYVCIAGRNKDMIIR"
     CDS_motif       10634..10687
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F8N66_RS01125_0001"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="F8N66_RS01125"
                     /protein_end="229"
                     /protein_start="211"
                     /score="17.9"
                     /tool="antismash"
                     /translation="IQYTSGTTGFPKGATLSH"
     CDS_motif       11201..11287
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F8N66_RS01125_0002"
                     /evalue="1.90E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="F8N66_RS01125"
                     /protein_end="429"
                     /protein_start="400"
                     /score="29.8"
                     /tool="antismash"
                     /translation="PRGTIGELCTRGYSVMLGYWNNPQGTAEA"
     gene            complement(12378..13277)
                     /locus_tag="F8N66_RS01130"
                     /old_locus_tag="PS918_00212"
     CDS             complement(12378..13277)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015094354.1"
                     /locus_tag="F8N66_RS01130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00212"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_150768426.1"
                     /sec_met_domain="HMGL-like (E-value: 8e-55, bitscore:
                     182.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLPTHVRLVEVGPRDGLQNEAQPISVADKVQLVDALTAAGLGYI
                     EVGSFVSPKWVPQMAGSAEVFAQIQRKPGVTYGALAPNLRGFEDALACGVKEVAVFAAA
                     SEAFSQRNINCSISESLERFVPIMDAARQHGVSVRGYVSCVLGCPYEGQVAPEQVARVA
                     RELYAMGCYEVSLGDTIGTGTAGATRRMFEVVSADVPREKLAGHFHDTYGQAMANIYAS
                     LLEGISVFDSSIAGLGGCPYAKGASGNVATEDVVYLLNGLGIDTGIDLDALILAGQQIC
                     SVLGRPTGSRVAKARNAQ"
     gene            complement(13423..13824)
                     /locus_tag="F8N66_RS01135"
                     /old_locus_tag="PS918_00213"
     CDS             complement(13423..13824)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007980992.1"
                     /locus_tag="F8N66_RS01135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00213"
                     /product="MerR family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_150768427.1"
                     /transl_table=11
                     /translation="MSSQTYSISDLARELDITTRAIRFYEEQGLLSPERRGQERIYSPR
                     DKVSLKLILRGKRIGFSLAECRELIELYDPSSGNTKQLHSMLAKISERREQLEQQLLDI
                     EQMKLELDTAEERCVQALEQTLKNQQAIQ"
     misc_feature    complement(13823..13837)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 23.51"
                     /tool="antismash"
     gene            complement(14020..14949)
                     /locus_tag="F8N66_RS01140"
                     /old_locus_tag="PS918_00214"
     CDS             complement(14020..14949)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1125: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008148497.1"
                     /locus_tag="F8N66_RS01140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00214"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_150768428.1"
                     /transl_table=11
                     /translation="MNLSKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLR
                     ETFNDPLFVRTAQGMVPTPMAQNIIGPVRNALSLLRVSVQESRIFNPLQAVKTYRISMT
                     DLTEAVILPPLFQRLRRLAPTVIIESFLSKRRETTKELAAGRLDFAVDAPLNTDPQVRH
                     VKLMEDRYVCAMRKGHPLAAKEKFTLDDYLGLTHIHISSRRSGLGHVDLALGKMGIQRK
                     IALRSQHYLMASQVLQQTDMVMTVPERFARRNDLHAFSLPVNDVPPVETHLYWHESTDQ
                     DPANRWMREQMIELCQQVTAHEKKLEKV"
     gene            15114..16343
                     /locus_tag="F8N66_RS01145"
                     /old_locus_tag="PS918_00215"
     CDS             15114..16343
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_251240.1"
                     /locus_tag="F8N66_RS01145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00215"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_150768429.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 9e-19, bitscore:
                     64.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.8e-20, bitscore:
                     68.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.4e-34, bitscore:
                     113.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFAYSPKVQELRERVTAFMDTYVYPAEAVFERQVAEGDRWQPTA
                     IMEELKLKAKAEGLWNLFLPESELGAGLTNLEYAPLAEIMGRSLLGPEPFNCSAPDTGN
                     MEVLVRYANEEQKQRWLEPLLRGEIRSAFAMTEPDVASSDATNMAARAVRDGDEWVING
                     KKWWTSGACDPRCKILIFMGLSNPDAPRHAQHSMILVPVDTPGVKILRPLPVFGYDDAP
                     HGHAEVLFDNVRVPYENVLLGEGRGFEIAQGRLGPGRIHHCMRSIGMAERALELMCKRS
                     VNRTAFGKPLARLGGNIDKIADSRMEIDMARLLTLKAAYMMDTVGNKVAKSEIAQIKVV
                     APNVALRVIDRAIQIHGGAGVSNDFPLAYMYAMQRTLRLADGPDEVHRAAIGKFEIGKY
                     VPKEMLRSGQ"
     gene            complement(16458..17792)
                     /locus_tag="F8N66_RS01150"
                     /old_locus_tag="PS918_00216"
     CDS             complement(16458..17792)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019648445.1"
                     /locus_tag="F8N66_RS01150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00216"
                     /product="phosphate ABC transporter substrate-binding/OmpA
                     family protein"
                     /protein_id="WP_150768430.1"
                     /transl_table=11
                     /translation="MTLRGLFLLMLWLPLTVLASSLPLPERGPVLRIQGSNTIGAALGP
                     ALVEGLLRQQGLVNVHRETPDTANELRIVGETVQGRRVEVELAAHGSSTGFSALKTGRA
                     DLAASSRPIKDREVADLQALGDLKSPGAEQVIAIDGLAIIVHPDNPLNQLDTEQLARIF
                     SGDANTWEDVGASGGPIHLYARDDQSGTYDTFKELVLSGRGKTLGSAAKRFESSEQLSD
                     AISLDPQGIGFIGLPYVRQAKAVAIVDGQSQAMLPQRSLIATEDYPLSRRLFLYLPPNG
                     KNPWAEALVTFAQSSQGQAIVAANGFIAQTVQAMAVVPNALMPEGYQGLSRHAQRLTVN
                     FRFEEGSASLDNKARQDLSRVLDYIKQHDKADRQVTLVGFGDAKSDLARADLLSKLRAM
                     AVRRELVKSGVVLREIRGFGAQMPVAANSADEGRIKNRRVEVWVY"
     gene            complement(17923..18735)
                     /gene="xthA"
                     /locus_tag="F8N66_RS01155"
                     /old_locus_tag="PS918_00217"
     CDS             complement(17923..18735)
                     /EC_number="3.1.11.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0008311 - double-stranded DNA 3'-5' DNA
                     exonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="xthA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_251235.1"
                     /locus_tag="F8N66_RS01155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00217"
                     /product="exodeoxyribonuclease III"
                     /protein_id="WP_150768431.1"
                     /transl_table=11
                     /translation="MKIVSFNINGLRARPHQLAALIEKHQPDVIGLQETKVHDDQFPLD
                     EVRALGYHVYFHGQKGHYGVALLSRQEPLALHKGFATDEEDAQRRFIWGTFADANGVPV
                     TIMNGYFPQGESRDHPTKFPAKERFYSDLQQLLESQFKNDQPLVVMGDVNISPEDCDIG
                     IGPDNMKRWLKTGKCSFLPEEREWMARLKNWGLVDSFRHLNPDVADRFSWFDYRSRGFE
                     DEPKRGLRIDLILASHGLLPRVKDAGVDYELRGMEKPSDHAPIWLELS"
     misc_feature    complement(18872..18887)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.32"
                     /tool="antismash"
     gene            19027..19677
                     /locus_tag="F8N66_RS01165"
                     /old_locus_tag="PS918_00218"
     CDS             19027..19677
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018925466.1"
                     /locus_tag="F8N66_RS01165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00218"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_150768433.1"
                     /transl_table=11
                     /translation="MPETSTAIADIHMLDSGYSREARSLLYQAYRHEPTFGYLFESERP
                     GYEQRVRATVRELVKQHFLQDLPAIGLLVNDRLIGIALIAPPQRRLGITESWAWRLRMV
                     LSTGFRCTRRYLEYHDAVAACVPSDSVHVLPLLGVHPQFQGKHFGEQLLQAVHNWCAVD
                     EHSQGVILDTGNPRYLEFYKRQGYEEIGEVAVGPIREHVFFHPNPQVVQSATA"
     gene            19757..21484
                     /locus_tag="F8N66_RS01170"
                     /old_locus_tag="PS918_00219"
     CDS             19757..21484
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007904105.1"
                     /locus_tag="F8N66_RS01170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PS918_00219"
                     /product="autotransporter assembly complex family protein"
                     /protein_id="WP_150768434.1"
                     /transl_table=11
                     /translation="MKFPGRITSGVLMLISSCAALAQSELDVRIKPSNDALKANIEGYI
                     GSLGDRDEEALLRFSRGAEEQARKAAQALGYYQPQIDSKVTGGKTPHLILDIDPGEPVH
                     LRNVTIRVDGPAASLKSFRVPKSHALQTGAVLNHGQYDDAKRLIQNQASRYGFFSGHFT
                     RSKLSVDPRAGVADIELIYDSGPRYSLGKISFEGDTPFDEDLLQRMVPFKEGTPYDSEL
                     IAELSQAMQSSGYFESVRVDAAPTASKNNVIPVDVKLETRKPRTMGLGLGYSTDVGPRI
                     KANWTRHWVNPQGHSYGWETEVSAPRQNVGVFYDIPLDPPLTDKLRFAGGYQNEEIADK
                     DSLSKLLTVGPEWHSKLPSGWQRVVSLKWQREEYRLGDDSGLSTLLMPGVSYTYLKSDN
                     RIDPHNGYRLAFETRVAKEGLGSDNNLLYGTALVKGLTTVFDKHRFLGRVQVGGSATNG
                     YTSVPPSLRFFAGGDQSVRGYDYQSLSPENNQGDRIGGRYMVAGSVEYQYSVAEKWRVA
                     TFVDQGNAFNTLELPSLKTGVGIGVRWVSPVGPIRLDLAHALDDDGGIRLHFSMGPEL"
     misc_feature    complement(22320..22334)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.85"
                     /tool="antismash"
     misc_feature    complement(22430..22445)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.49"
                     /tool="antismash"
     misc_feature    23201..23215
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.84"
                     /tool="antismash"
ORIGIN
        1 tggacattca caagtccttc ggtgacctgg aaattctcaa gggcatttcc ctgcaagtgc
       61 gacggggcga agtggtggtg ctgatcggtg cgtccgggtc cggcaaaacc acgttcattc
      121 ggtgtatcaa cttgctggag gacattcagt ccggacagat ccgtgtgtct ggcaagccga
      181 tggggtatcg cacccgggcc gacggcagcc tggcccgtga ttcggaacgc aacatcgccc
      241 gccagcgccg ggacatcggc atggtgttcc agcgcttcaa cctgttcccg cacatgaccg
      301 ccctggaaaa catcatcgaa gcgcccatcc aggtgctggg ggtggcccgc gcggcggcgg
      361 tcgagcaggc gcgcgccttg ctcaagcgcg tcgggctggc ggagaaggcg gatcactatc
      421 cgtcgatgtt gtccggtggc cagcagcagc gggtcgcgat tgcccgggca ttggccatga
      481 aaccgcaggc gatgctgttc gacgaaccca ccagtgccct ggatccggag acggtcggcg
      541 aagtgctgca ggtgatgaag gagctggccg aggagggcat gaccatggtc gtggtcaccc
      601 acgaaatggg gtttgcccgg gaagtggccg accgggtggt ggtgctcgac cagggcgaac
      661 tgatcgaaca gggcccgccg gagcagatct tcagccagcc cgtccatgcc cgtacgcggg
      721 cgttcctcag ccgcgtgttg tgaacccgtc aaaaactttt gtgtgagtct gccatgttca
      781 aattttctgc ccatgagtat ccctacgcct cacaacgtca aagtgtcttc gccaagcgtg
      841 gcatggtcgc cgcttcacag ccgctggccg ccgaggccgg gatcgaaatc atgcgtcgcg
      901 gtggcaatgc catcgatgcc gccatcgcca cggccgcggc gctcaccgtg gtcgagccca
      961 ctggctgtgg catcggcggt gatgcctttg cgctggtctg gacgcaaaac aaattgcacg
     1021 gcttgaacgc caacggtgcg gccccgcaag ccttgagcat cgacgcggtg aaagccgccg
     1081 gccatgaaaa gatgccgttg catggctgga cgccggtgac cgtcccaggc tgcccgtcgg
     1141 cctgggcgga attgtccacg cgctttggcc gactgccgtt tgccgatgtg ctgcaaccgg
     1201 cgatcaacct ggcgcgggat ggttttccgg tgtcaccggt ggttgccctg cagtggcaaa
     1261 ccgcgctgga ggatttcacg ccggaccgta gcgaagtcct tgagagctgg ttcgagacct
     1321 ttctgatcga cggccgcgcg ccccgtgccg gtgaactgtt tcgcaacccg gcgcaggccc
     1381 ggaccttgag tgaactggcc gccacggggt gtgaaagttt ttatcgcggt gcgctggcgc
     1441 agcggctgga tgcccactcc cgggccacgg gcggttactt gcgtgccagt gacctgaagg
     1501 attaccgcgc gcaatgggtc gagccgatca aggtcaacta tcgcggtgtc gatgtctggg
     1561 agattccacc gagtggccaa gggctggtgg cgctgatgac gttgaagatt ctcgagggct
     1621 tcgacttcga tcatcgcgac agccagcaaa cctggcaccg ccagctcgaa gccatgaagc
     1681 tcgcttactg cgatggcctg cactacatca ccgatcctgc gcacatgcgg gttgccgtgg
     1741 acgacttgtt gagcgaccac tatgcggctc atcgccgggg gcagatcggt gagcgggccg
     1801 tggcgccgca gccgggcgac ccccatgcca gcggcacggt gtacctggcc accgccgatg
     1861 gcgaaggcaa catggtttcc ttcatccaga gcaactatca cggtttcggt tccggcgtgg
     1921 tgctgcccga cagcggtatc gccctgcaga accggggaga agaattcagt cttgatcccg
     1981 ggcattccaa ttgcctggcc ccgggcaaga aaaccttcca taccatcatt ccagggttcc
     2041 tcagcaagga cggtgaggcg atggggccgt ttggcgtcat gggtggctac atgcagccgc
     2101 aagggcacgt gcagatggtg atgaacctgg tggacttcgg gctcaacccg caagcggccc
     2161 tggatgcgcc gcgctggcaa tggctgggtg gactgaaggt cggtatcgaa caggacgcat
     2221 cgagagacct ggcggcggca ttggcacgcc gggggcatgc ggtggaagtg gcctgcgacg
     2281 tcaccagtta cgggcgggga cagatcatcc tgcgcgatcc tgaaacgggt gtgctatgcg
     2341 ggggtaccga accgcgtacg gattcacata ttgctgtgta ttgagggagg aaagggcggt
     2401 gagggtgcga tgccttcacc tgcctcgcag cgagcatttc atgatgaatg atcaccgcaa
     2461 tgtgcggggc ggaggcaggg ggaacggggg gcgtcgtcct tgacgccgac gcagcttaga
     2521 gattatgcga ttgattctca agtgctattt gccattactt tgccccattg atcaaaggca
     2581 tctcttgcca acaaatattc ttttgatatg atccgcgcca tcgaatttgc ggcacctaaa
     2641 gacttcatta gcctgaagcc ataagccaga aaactggcaa aaaaagaccc ggcaaaaagc
     2701 cgggtcaaaa accgtgatta gcctgatgag gagatagtcc aggagaccga cctaaggtcc
     2761 ctggtccatc gactgatctc gcgaccagct gatgcaataa taatcattct cgtttgcaag
     2821 tcaaacattt ttatctgcgc gatcggaaaa ttctttccag tcctctcttt ttgcatcttc
     2881 gcttcaaccg ttctgatgcc tctccagcga ccggtccacc atggctttgg ccatgtcgat
     2941 catatgcacc gccgaaaacg ccaggtcccg gtttgttccg tgcaggtgac tggctgattc
     3001 ataggccgtg gctgccgcgc aacgcaacag gtccgaggcg tggaccagcg cctcctcgct
     3061 gctgatattt cggttcacat caaagaaacg cgccccgacc tcttcctctg aaacaactgg
     3121 tttcaagtag tagtccagcg cgcgctgtgc ggccgccgac ccttgggggg aggtgaggga
     3181 cgtgtcgatg ggtatatccg gcagttcgtt ggcaggttgg gtcatgatga tggcaaagct
     3241 ccgtgatagg ttcagatccg taagctcata ctaatacgat ctgtatttgt gaccataaat
     3301 taaatactac aatttgtgtt ttgatggccg gaggcgccca cgtatcgtgc cgcacatgga
     3361 taaatggatt gaattggtca agaccaagat gagtgaactc aaagtcactc aagagatact
     3421 cgccgagcgc ctcgggatgt cccagggtgg cgtcgggcac tggctgacga aacgccgcca
     3481 gccaggcatc gacgacatga atcgcgtcct gcaggcgctg ggcctggggt ttctggaagt
     3541 ggcgctggtg atcagggaac ctcaggacgc ccaggacgag gaactgtccc tgacgcaaaa
     3601 atacaatccg tactttcgct acccggtcag cgattggcgg gaaacgagtg aggtccgcga
     3661 tggcgaacag gggcaatacc gtttcgaact gtccgactat cacgcacaag gcgcggcgtt
     3721 ctggctgaca gtggtgggcg atgcgatgac agcgcccagt ggcctcagca ttgccgaggg
     3781 catgttgatc ctggtggacc cggatgtgga agtcgagccc ggcaaactgg tcatcgccca
     3841 atgggcgaac agcagcgagg caatgtttcg caagctgatc gaagagggcg ggcagcgtta
     3901 cctggtcccg ctcaatccga catacccgaa agccctgtac accgaagagt gccgaatcat
     3961 cggcgtggtg gttcaggcga ccgtcaagtt ctgatcagat cggtcctcgg cgggtgcagg
     4021 accgatcttc atttcaggcc tcttccaact cgaccagcgc actgccttca ctgaccatct
     4081 cgccttcctg gcaatacagc gccttgatca cgccggcgtg gggcgcgcga atgctgtgct
     4141 ccatcttcat cgcttccagc accaccagtt gcgccccggc ttcgaccgtt tgcccggcct
     4201 ccaccagcac gcgcacgatg ctgccgttca tgggcgcggc cagcccgcca tgatggctgt
     4261 gactggcttc aacggcgctg atcgggtcat agggctcgat gcggcgcagt tcgccttccc
     4321 attgcaggta tacgaattcg ccacggcgaa tcgcccggtg ctggcggcgc acgccgtcgt
     4381 gttcggtcag cagatgctcg cccttgagtt gtgcgccgtg actgtcgggc gcgcccagcg
     4441 tcaatgcgcg gtcctggcct tcacaactca ggtgcagggt gatttgcgct ggcaacccgg
     4501 cccggaagcc gttgccgacg gcccatggcg aactcgagtc atcgctacgc ggtgcgcggt
     4561 gctggctctg ggcaaatgcc tgggcggcgg cttgccagaa ttcatcactg aggtccgaag
     4621 gcgccggcag aagttgttcc tgatagcgcg ggataaaccc ggtatccagt tcggcggcgg
     4681 cgaacgctgg atgcgcaatg atccggcgca ggaagttgat gttggtcttg aggccgccaa
     4741 tggcgaactc atcgagcatg ctcagcaggc gcaagcgtgc ctgttcgcgg tcttcgcccc
     4801 aggcaatcag cttgccgagc atcgggtcgt agaacggcga aatttcatcg ccttcttcga
     4861 caccgctgtc cacccggcga cccgcgcccg gcgcggattc acggtacaga tccaggcgac
     4921 cggtcgccgg caggaagtca ttgcccggat cttcggcata cagccgtact tcaatcgcat
     4981 ggccgatcag cggcacctgg tcctgggtca tcggcaacgc ttcgccacgg gccacgcgga
     5041 tctgccacgc caccagatcg aggccggtga tggcctcggt gaccgggtgt tcgacctgca
     5101 ggcgcgtgtt catctccatg aagaagaact cgccgcgcgc atccagcaaa aattccacgg
     5161 tgccggcacc gacgtaaccg atggcctggg ccgaacgcac ggcggcttcg cccatggcgc
     5221 ggcgcagttc cgggctcagg ccgggcgccg gcgcttcttc gacgactttc tggtgccggc
     5281 gctgaatcga gcagtcacgt tcgttgaggt acaggcagtg gccgtgttga tcggcgaaca
     5341 cctggatttc cacgtggcgc ggcttgagca ggtacttctc caccagcatc cgcgaatcgc
     5401 cgaacgacga ctgcgcttca cgctgggccg aggccagggc ttcggccagc tggctgacgt
     5461 cctcgaccac tttcatgcct ttgccgccac ccccggcggt ggccttgagc agcaccgggt
     5521 aaccgatgcg ttcgcaggca tcgcggaagg tgtcgaggtc ttgcgcttcg ccgtgataac
     5581 ccggcaccag cggcacgccg gcggtttcca tcagggcctt ggcggcggat ttgctgccca
     5641 tggcgtcgat ggccgaggcg ggcgggccga ggaagatcag gccggccgct tcaatcgcgc
     5701 gggcgaaccc ggcgttctcc gagagaaagc cataaccggg gtggatcgcc tgggcgccgc
     5761 tggccttggc cgccgcgatc agtttgtcga tttgcaggta gctgtcggcg gccttgctgc
     5821 cgccgagatc gacgcggata tcggcttcgc ggctgtgccg tgcgtcacgg tcggtggcgc
     5881 tgtgcacggc cacggtggtc aggcccaggg ccttggcggt gcgcatcacc cggcaagcga
     5941 tttcgccgcg gttggccacc agcagggtag tgaggacggg tgcgctcatc aacgcgactc
     6001 cttgggggtg attgcggctt gccagctcgg cgcacgtttt tgcaggaagg cgcgcaggcc
     6061 ttcctggcct tcggggctga cgcggatgcg ggcgatggcg ttctcggtgt agcggcgcag
     6121 cgccgggagc agcgagccgt cgccgacttc acgcaacaag tccttgctgg cccgcatggc
     6181 ggcggggctg ttgagcagca agttgtcgat ccactgttcg acgcgctgtt ccagctcgga
     6241 cgatggatag ctctccgaca gcagacccag ttcccgcgcc cgttggccgt cgaagcgttc
     6301 agcggtcaag gcatagcggc gcgtggcgcg ttcgccgatg gcttgcacca cgaacgggct
     6361 gatcaccgcc ggggccaggc cgatgcgcac ttccgacagg cagaactgcg cgtcatcgac
     6421 gccgatggcc atgtcgcagc aactgatcag gcccagtgcg ccgccaaagg ctgcgccttg
     6481 caccacggcc agggtcggga gtttcagttt ggccaggttg tacatcaact ccgccagttc
     6541 ccgggcgtcg tcgaggttgg tgtggtagtc gagctcggcc gattgctgca tccacgccag
     6601 gtcggcgccg gcgctgaaat gcttgccgcg accccgtacc agcaggaaac gcaggctggc
     6661 atcgctggac acgtggtcca gggcgatgat cagttcgcgg atcatttcgg cgttgaacgc
     6721 gttgttcttt tcttcgcggc taagccacag ggtggcaaag ccccgtgggt cggtcagcag
     6781 ttcgagggtg ttgaagtcgc tcatattctt ccgttctcca cggtctttgt gggagcgggc
     6841 ttgctcgcga agaacgataa cgcggtgcat cagataaacc gcggtgaatc cttcgcgagc
     6901 aagcccgctc ccacaaaaaa aattacatcc ggaacacgcc gaagcggctc ggttcgattg
     6961 gcgcgttcag cgacgccgac agggccagtc ccaggacatc gcgggtctgt gccgggtcaa
     7021 tgacgccgtc gtcccacaag cgagcgctgg aatagtaagg gtggccctgt tcttcgtact
     7081 gatcgaggat tggctgcttg atctcggctt cctgctcggc gctgaaaccc tggccgctac
     7141 gttcggcctg ctcgcgcttg acctgcacca gcacgccggc ggcctgttcg gcacccatca
     7201 cgccgatgcg cgcgttcggc cacatccaca ggaaacgcgg gtcgtaggct cgaccgcaca
     7261 tgccatagtt accggcaccg aaactgccgc cgatgatcac ggtgaacttc ggcaccttgg
     7321 cgcaggccac agcggtcacc agtttcgcgc cgtgcttggc gatgccgccg gcctcgtatt
     7381 tctgcccgac catgaaaccg gtgatgtttt gcaggaacag cagcggaatg ccgcgctggc
     7441 aggccagttc gataaagtgc gcgcctttct gcgccgcttc agcgaagagg atgccgttgt
     7501 tggccaggat cgcgatcggg taaacgtgca ggtaggcaaa accgcacacc agcgtggtcc
     7561 cgaacaaggc cttgaactcg tcgaacaccg agccgtccac cagccgcgca atgacttcgc
     7621 gcacgtcgaa gggttgcttg gcatcggccg gcaccacgcc gtacaactcg tcgctgctgt
     7681 agagcggagc aatgggcgtg cgttgctgca cctcaccgag cttgcgccag ttgaggttcg
     7741 ctacgctgcg acgggcgatg gccagggcgt gttcatcgct ctcggcgtaa tggtccgcca
     7801 cgccggaaat cttgcagtgc acgtcggccc cgccgaggtc ttcggcgctg accacttcac
     7861 cggtcgcggc tttcaccagc ggcgggccgg cgaggaaaat cgtcgcctgc tcgcgcacca
     7921 tgatcgcttc gtcggccatc gccggcacat aggcgccgcc cgcagtgcag gagcccatga
     7981 ccacggcaat ctgcgggata cccagggcgc tcatgttggc ctggttgaag aaaatccggc
     8041 cgaagtgctc acggtccggg aagacttcat cctggcgcgg caggttggcg ccaccggagt
     8101 ccaccaggta aatgcagggc aggcggttct gctgggcgat ggtctgggcg cgcaggtgtt
     8161 ttttcacggt cagcgggtag tacgagccac ccttcaccgt ggcgtcgttg gcgacgatca
     8221 tgcattcgac gccttccacg cggccaatcc cggcaatcac gccagcggcc ggaacgtctt
     8281 cgccatacac ctcgtaggcc gccaactggc tgatttcgag gaatggcgaa cccggatcga
     8341 gcaggcgatt gatccgctca cggggcagca atttaccccg cgaggtgtgg cgttcttgcg
     8401 ccttcgggcc gccaccttgc gccacttggg caagcagggt gtgcagggcg tcgacctgtt
     8461 tgagcatcgc cgcgctgttg gcggcgaatt ccgctgaacg ggggttgagc tgggtatgca
     8521 gggtagccat gggcagctcc gttagcgggt ttcgttaaac agttcgcgac cgatcagcat
     8581 gcgacggatc tcactggtgc cagcaccgat ttcatacaac ttggcgtcac gcagcaggcg
     8641 accggccggg aattcgttga tgtaaccgtt gccgccgaga atctggatcg cgtcgagggc
     8701 catttgcgtg gcgcgttcgg cgctgtagag gatcacgccg gcggcgtcct tgcgcgtggt
     8761 ttcgccgcgc tcgcaggcct gggccacggc gtacaggtag gcccggctgg catttagttg
     8821 ggtgtacatg tcggcgacct tgccctggat cagctggaac tcgccgatgc tttggccgaa
     8881 ctgcttgcgg tcgtggatgt acggcacgat caggtccatg caggcctgca tgatcccggt
     8941 cgggccgccc gagagcacca cgcgctcgta gtcgaggccg ctcatcagca ccttcacgcc
     9001 accgttgagt acgccgagga tgttttcttc cggcacttcg acgtcatcga agaacagctc
     9061 gcaggtgttg gagccgcgca tgccgagctt gtcgaacttg ttgctgcggc tgaagccttt
     9121 ccagtcgcgc tcgacgatga aggcggtgat gccgtggggg cctttttcca ggtcggtctt
     9181 ggcgtagatt acataggtgt tggcgtccgg accgttggtg atccaggtct tgctgccgtt
     9241 cagcacgtat ttgtcgccgc gcttatcggc gcgcagcttc atcgagacca cgtcggaacc
     9301 ggcattcggt tcgctcatcg ccaaggcgcc gatgtgctcc ccgctgatca gcttcggcag
     9361 gtacttgagt ttctgctcat gattgccgtt gcggttgatc tggttgacac agaggttgga
     9421 gtgcgcgccg taggacaacg ccaccgaggc cgagccacga ctgatttctt ccatcgccac
     9481 cacgtgggcc aggtaaccca ggccggcgcc gccgtactcc tctggaaccg tgatgcccag
     9541 caggcccatg tcgccgaatt tgcgccacag gtcagcgggg aacaggttgt cgatgtcgat
     9601 ctgagcggcg cggggggcga tctctttggc gacgaaggac tgaacctgat cgcgcagcat
     9661 gtcgatggtt tcaccgaggg caaaattcag ggatgggtag ctcatgggtc accttttggc
     9721 ttttttgtcg ggtggggagg gcggtggttc agctctcacc tttacgttaa cgtaagcctg
     9781 tgacgaatgg ctgtcaatca ccctttacgt taacgtcaac ttgagcgaga gtagaggcag
     9841 ttcaagatag aacgcgggcc accattgtgg gagcgggctt gctcgcgaaa gcgctgtgtc
     9901 attcaacgtt gatgtcgact gacacagcgc tttcgcgagc aagcccgctc ccacaggggg
     9961 caccgccggt agcccataaa taaagacaat aggggtcgtc atggatcaac ccagtgcaag
    10021 cccgcaacgc agttacaccc gtggttccca ggacaaagcc ttgctggcga tgaccatcgg
    10081 ccaggcgttc gagaacacgg tcgcgcagta cccggacggg gaggcgctgg tcgtgcggca
    10141 tcaacagttg cgctacacct ggcggcaact ggcgcacgcc gcggacctgc acgccagggc
    10201 actgctggcg ctgggcctgc aggccggtga ccgtcttggc atctgggcac ccaactgcgc
    10261 ccagtggtgc atcacccaga tcgccacggc gaaaatcggc gtgatcctgg tcaacatcaa
    10321 cccggcctac cgcagttccg aacttgaata cgtgttgaag caatccggct gtcagtggct
    10381 ggtgtgcgcc ggggctttca agacctccaa ctaccacgcg atgctccagg gcctggtgcc
    10441 cgagctggcg gagcaacccg tcggcaagtt gcacagcgag cgcctgcccg aactgcgtgg
    10501 cgtcatcagc ctggatgcgc agcccccagg cggtttcgtg ccctgggcgc aactggcgga
    10561 tctggccggc agcgtatcgg accaacaact gcacgaacgt caggagagcc tgcatttcga
    10621 ccaggcggtg aacattcagt acacctccgg taccaccggt ttccccaagg gcgcgaccct
    10681 tagccactac aacatcctca acaacggtta catggttggc gaaagcctcg gccttaccgc
    10741 cgctgatcgc ctggtgatcc ccgtgccgct gtatcactgc ttcggcatgg tgatgggcaa
    10801 tctgggttgc atcacccacg gcagcaccat gatttatccc aatgacgcct tcgatccgtt
    10861 gctgaccctg aatactgtcg ccgaagaaaa agccaccgcg ctgtacggcg tgccgaccat
    10921 gttcatcgcc atgctcgatc agccgcaacg cgcggaattc gacctgtcga gcctgcgcac
    10981 cgggatcatg gcgggggcga cgtgccctat cgaagtgatg cgccgggtga tcaatgaaat
    11041 gcacatgagc gaagtgcaga ttgcctacgg catgaccgaa accagcccgg tgtcgttgca
    11101 gaccgggccg tccgacgatc tggagctgcg cgtcaccacg gtgggccgca ctcagccgca
    11161 gctggaaagc aagattatcg acgaagcggg caacctggtg ccgcgcggca ccatcggcga
    11221 actgtgcacc cggggctaca gcgtgatgct cggctactgg aacaacccgc aaggcaccgc
    11281 cgaggcgatc gaccaggcgg gctggatgca caccggtgac ctggcgagca tgaacgacga
    11341 gggttatgtg tgcatcgccg ggcgcaacaa ggacatgatc attcgtggcg gcgagaatat
    11401 ttacccgcga gagctggaag agttcttctt cacccacccg gccgtggccg acgtgcaggt
    11461 gatcggtatt ccatgctctc ggtatggcga agagattgtc gcctggatca agttccaccc
    11521 ggggcacagc gcgagcgaac aggagttgca agcctggtgc aaagagcgca tcgcgcactt
    11581 caagacgccg cgttacttca agttcgtgga agaattcccg atgaccgtga ccggcaagat
    11641 ccagaaattc aagatgcgcg agattagtat cgaggagttg cgcattaata aggcatgacc
    11701 caaaacctgt gggagcgggc ttgctcgcga atacggtata cctgtcgaca catgcgctgg
    11761 caggcactcc gcattcgcga gcaagcccgc tcccacaggg ttttgcatga ttatctaaat
    11821 cgcagacagc acaaagggga gccgaggctc ccctttaatt gtcgttgcgc gtgctctttt
    11881 tttattattg aggggcggtc tgtttttgtt tttggcaacc gttgcccttt accgctgttt
    11941 ttggcgatcc ccatccggga tcaagagcaa acgtattttt ttgagcgctg atctactttt
    12001 tcgctgagcg atccaaccag ttcgggagct acctgaaggt agttttattg ttctctgccc
    12061 ggttgcgggt tactccgaaa agcaccctga aaagcacatc ttctccaaaa aaatctgtta
    12121 gctgcgtctc tgccgtgttg tttttgttat gtcagagtcg ttacgtcttg tttttattag
    12181 gtgtgtcgca attttttatt cttgttgtgc catagagata gcagttcccg tgccaacttt
    12241 taaaaaccct ttaaaatcaa caacttagta ttttgtggga tttttctctc agggaatccc
    12301 tgacaatttg tttccgtgtt actcgctgcc gcccacattt tcagcgtggg cggtaacacc
    12361 cggacacacc cgcacactca ctgcgcgtta cgggccttgg ccacacgtga accggtcggg
    12421 cgccccagca cagagcaaat ttgctgaccg gccaggatca gcgcgtccag gtcgatgccg
    12481 gtgtcgatgc ccaggccgtt gagcaggtaa accacgtctt cggtggcgac gttaccgctg
    12541 gcgcccttgg cgtaggggca gccaccgagc ccggcgatgg agctgtcgaa caccgagatg
    12601 ccttcgagga ggctggcgta gatgttggcc atggcctggc cgtaggtgtc gtggaaatgc
    12661 ccggccagtt tttcccgggg gacatcggcc gataccacct cgaacatccg gcgggtggcg
    12721 ccagcggtgc cggtgccgat ggtgtcgccc aaagacactt cgtagcagcc catggcatag
    12781 agctcgcggg cgacccgggc gacctgttcg ggggcgacct gaccttcata agggcaaccc
    12841 agcacacagg acacgtaacc gcgcacactc acgccgtgct gtcgggcggc gtccatgatc
    12901 ggcacgaaac gctcaaggct ttcgctgatc gagcaattga tgttgcgctg ggaaaaggct
    12961 tcggacgccg cggcgaacac cgccacctcc ttgaccccgc aggcaagggc atcctcaaag
    13021 ccacgcaggt tgggcgcgag tgcgccatac gtgacgccgg gcttgcgctg gatctgcgcg
    13081 aagacctcgg cggaaccggc catctgcggc acccatttgg gcgagacgaa actgccgact
    13141 tctatatagc caaggcccgc ggccgtgagc gcgtcgacca gttgcacctt gtcggcgacg
    13201 ctgatgggtt gggcttcgtt ttgcaggccg tcgcgggggc cgacttcgac caggcgtacg
    13261 tgggtgggaa gggacatggg taattcacct gtattaatgg gtgaacgacg atcccgtgtg
    13321 ggagcgggct tgctcgcgaa agcggtgggt cagtcgacat ccctgttgga tgaaaagccg
    13381 cattcgcgag caagcccgct cccacacggg atcgtcgtat gattattgaa tggcctgttg
    13441 attcttgagg gtctgctcca gcgcctgcac acagcgctct tcagccgtgt ccagctcgag
    13501 tttcatctgt tcgatgtcca gcagctgctg ttccagctgt tcccggcgct cgctgatttt
    13561 tgccagcatg ctgtgcagtt gcttggtgtt accgctggac gggtcgtaga gctcgatcaa
    13621 ctcgcggcat tcggccagcg aaaagccgat gcgcttgccc cgcaggatca acttcaggct
    13681 gaccttgtcc cggggcgaat agatgcgttc ctggcctcgg cgttcggggc tgagcaagcc
    13741 ttgctcttca tagaagcgaa tggcccgggt ggtgatgtcg agctcgcggg cgaggtcgga
    13801 aatgctgtag gtctggctgc tcatgggcgc gctcgcaaaa ggtcatggcg ctaagctaat
    13861 ggcaggttga cgtttacgtc aaggggcagg ggttttcagt gtcgtcgcgg gcctcttcgc
    13921 gagcaagccc gctcccacat tcaaccgcgc tcctccagaa agaacgcgtt cagtgtggga
    13981 gcgggcttgc tcgcgaaagg ggcagcgcgg tggagcgtcc tacaccttct ccagcttctt
    14041 ctcatgcgcc gtcacttgct ggcacaactc gatcatctgc tcgcgcatcc agcggttggc
    14101 cgggtcctgg tcggtgcttt cgtgccagta gaggtgggtt tccaccggtg gcacatcgtt
    14161 gaccggcagg ctgaaggcgt gcagatcgtt tcggcgggcg aagcgttccg gcacggtcat
    14221 caccatgtcg gtctgttgca gcacttgcga agccatcagg taatgctggg agcgcagggc
    14281 gatcttgcgc tggatgccca tcttgcccag ggccaggtcg acatggccca ggccgctgcg
    14341 acggctggaa atatggatgt gcgtcaggcc gaggtaatca tcaagggtga atttttcttt
    14401 cgccgccagc gggtgcccct tgcgcatcgc acacacgtag cgatcttcca tcaacttgac
    14461 gtggcgtacc tgcgggtcgg tgttgagcgg cgcatccacg gcgaagtcga ggcgaccggc
    14521 cgccagttcc ttggtggtct cgcggcgctt ggacaggaaa ctctcgatga tcaccgtcgg
    14581 cgcgaggcga cgcaggcgct ggaacagcgg cggcaggatc acggcttcgg tgaggtcggt
    14641 catgctgatg cgataggtct tgaccgcctg cagcgggttg aaaatgcggc tttcctgcac
    14701 cgatacccgc agcagcgaga gggcgttgcg caccgggccg atgatgttct gtgccatcgg
    14761 cgtgggcacc atgccttggg ccgtgcgcac gaacaatgga tcgttgaagg tctcgcgcag
    14821 gcgggccagg gcgttcgaca ccgctggctg agtgatgccg acaatctgcc cggcacgggt
    14881 caggttggct tccgtgtaga tcgcgtcgaa gacgatgaaa aggttgaggt cgaccttgct
    14941 cagattcata tacgcggctc tcttattgtg tggacgggta gccgtggcta tcagtcgatc
    15001 atatatcggt gatgaatgtt aatacacgcc gagaataggc taggtaaatt ttcatggctg
    15061 ttctagcatc gattgcatga cctaaacaac ctccctcaag aaggtagctg ctcatggatt
    15121 tcgcttattc gcccaaggtt caggaactgc gtgagcgcgt gaccgcgttc atggacacct
    15181 acgtttatcc cgctgaagcc gtgttcgagc gtcaggttgc cgagggcgac cgctggcagc
    15241 cgacggcgat catggaagaa ctcaaactca aggcaaaggc cgagggcctg tggaatttgt
    15301 ttctgcctga gtcggaactg ggtgccggcc tgaccaacct cgaatacgcg ccgctggcgg
    15361 aaatcatggg ccgctcgctg ctcggtccgg agccgttcaa ctgctcggcg ccggacaccg
    15421 gcaacatgga agtgctggtg cgctacgcca acgaagaaca gaaacagcgc tggctcgaac
    15481 cgctgctgcg cggcgagatc cgctcggcgt tcgccatgac cgaacccgac gttgcctcct
    15541 ccgatgccac caacatggcg gcccgcgcgg tgcgcgatgg cgatgagtgg gtgatcaatg
    15601 gcaagaagtg gtggacttcc ggcgcctgcg acccgcgctg caagatcctg atcttcatgg
    15661 gcctgagcaa ccctgatgcg ccgcgtcacg cccagcattc gatgattctg gtgccggtcg
    15721 atacccctgg cgtgaagatc ctgcgtccgc taccggtgtt cggctatgac gatgcccccc
    15781 atggtcacgc cgaagtgctg ttcgacaacg tgcgggtgcc gtacgaaaac gtcctgctgg
    15841 gcgaaggacg cggcttcgag attgcccagg gtcgccttgg ccctggccgg attcaccact
    15901 gcatgcgctc gatcggcatg gcggagcgcg cgctggaact gatgtgtaaa cgctcggtga
    15961 accgcacggc gttcggcaaa cccctggcgc gcctgggcgg caacatcgac aagatcgccg
    16021 actcgcggat ggaaatcgac atggcgcgcc tgctgacgtt gaaagcggcc tacatgatgg
    16081 acaccgtcgg taacaaggtg gcgaagagcg aaatcgcgca aatcaaggtg gtggcgccga
    16141 acgtggcctt gcgggtgatc gaccgggcga tccagattca tggcggggca ggggtgtcga
    16201 acgatttccc gctggcgtac atgtatgcga tgcagcgcac cctgcgcctg gccgacggcc
    16261 cggatgaagt gcaccgcgcg gcgatcggca agttcgagat cggcaagtac gtgcccaaag
    16321 agatgttgcg tagcggccag taagttcgag tcgcctgcca ttcgcgagca agcccgctcc
    16381 cacaggattt acgctagccc tgtgggagcg ggcttgctcg cgaagacgtc aggcccatca
    16441 ccacagaaac atcagattca atacacccaa acctcaaccc gccgattctt gatccgcccc
    16501 tcatccgcgc tgttggccgc caccggcatt tgcgcgccga agccgcgaat ctcgcgcaac
    16561 accacgccgc ttttcaccag ctcccgtcgc acggccatgg cccgcagttt cgacaagagg
    16621 tcggcccgcg ccaggtcgct cttggcatcg ccgaatccca ccagcgtcac ctgccggtcg
    16681 gctttgtcat gctgctttat atagtcgagc acccgcgaca ggtcctgccg ggccttgttg
    16741 tcgaggctgg cgctgccttc ctcgaaacgg aagttcaccg tcagccgctg ggcgtgacgg
    16801 ctcagtccct ggtaaccctc gggcatcagc gcattcggga cgacggccat ggcctgcacg
    16861 gtctgggcga taaaaccgtt ggcggccacg atcgcctgac cctggctgct ttgcgcgaac
    16921 gtcaccagcg cctcggccca ggggtttttc ccgttcggcg gcaagtaaag aaacaatcgg
    16981 cgggacagcg gatagtcttc ggtggcgatc aggctgcgct gcggcaacat ggcctgggat
    17041 tggccgtcga cgatcgccac ggctttggcc tggcgcacgt agggcaggcc gatgaaaccg
    17101 atgccttgcg ggtcgaggct gatcgcgtcg gacaattgct cgctggattc gaaacgtttc
    17161 gcggcgctgc ccagggtttt cccgcgaccg ctgagcacca gttccttgaa cgtatcgtag
    17221 gtgccggact gatcgtcccg cgcatacaga tgtatcggcc cgccgctggc accgacgtct
    17281 tcccaggtgt tggcgtcgcc actgaaaatg cgcgccagtt gctcggtgtc gagctggttc
    17341 agtggattgt ccggatgaac aatgatcgcc aggccgtcga tggcgatgac ctgttcggcg
    17401 ccggggcttt tcaggtcgcc cagcgcctgg aggtccgcca cctcgcgatc cttgattggg
    17461 cgcgaagaag cggcgagatc ggcgcggccg gtcttcagtg cactgaaacc ggtgctggaa
    17521 ccgtgggccg ccagttccac ctcgacccgg cgtccctgga cggtttcacc gacgatgcgc
    17581 aattcattgg ccgtgtccgg ggtctcgcgg tgtacgttga ccaggccctg ctggcgcagc
    17641 aagccttcga ccagcgccgg gcccaatgcc gcgccgatgg tattggaacc ctggatgcgc
    17701 agcaccgggc cccgttcggg caggggcagg ctgctggcta gaaccgtgag cggcaaccag
    17761 agcatcaaca ggaacaaccc gcgcagcgtc atgccggcac cttacatagc gaaagaggtg
    17821 tcgggagatt aagtcagtaa ggtttccgaa atatgacaga tcaaaggatc gcaacctgcg
    17881 gcagctcctg taggagctgc cgcaggctgc gatcttttac tttcagctca attcaagcca
    17941 gatcggcgca tgatccgagg gcttttccat gccgcgcagt tcgtagtcca cgcccgcatc
    18001 cttgacccgt ggcagcaagc cgtgggacgc caggatcaag tcgatccgca ggccacgctt
    18061 gggctcgtct tcgaacccgc ggctgcggta gtcgaaccag ctgaagcgat cggccacgtc
    18121 cgggttgagg tggcggaagc tgtccaccag gccccagttt ttcaatcggg ccatccattc
    18181 gcgctcttcc ggcaggaagc tgcacttgcc ggttttcagc cagcgtttca tgttgtccgg
    18241 gccgataccg atgtcgcaat cttccgggga aatgttcacg tcgcccatga ccaccagcgg
    18301 ctggtcgttc ttgaactggc tttccagcag ttgctgcaag tcgctgtaga agcgttcctt
    18361 ggccgggaat ttggtggggt ggtcgcggct ttcgccttgt ggaaagtagc cgttcatgat
    18421 ggtcaccggc acgccattgg catcggcgaa ggtgccccag atgaagcgtc gttgcgcgtc
    18481 ttcttcatcg gtggcgaagc ccttgtgcaa ggcaagcggt tcctggcgcg agagcagggc
    18541 aacgccgtaa tggccctttt gcccatggaa atacacgtgg tagcccaggg ccctgacttc
    18601 atcgagtggg aattggtcgt cgtggacttt ggtttcctgc aggccgatca catcgggctg
    18661 gtgcttttcg atcagcgccg ccagctgatg gggacgggcg cgcagcccgt tgatgttgaa
    18721 ggagacaatc ttcatggtcg gcagtcctgg caaaagggcg atgctagctg acatgcgggg
    18781 ttggggccag tgtcgggatg gggtcttcag tcagatcttt attgactgtt ccggcctctt
    18841 cgcgagcaag cccgctccca cagggttcga gtctggtcta tacctttgtg ggagcgggct
    18901 tgctcgcgaa ggcgccgccc gatccacgct gatttcagat cacaacggaa ctgtgcaggc
    18961 accgccaggc tcgtacccat aagaaagagc gcagccaccc gagccgcgcc ggggagatca
    19021 accgtcatgc ccgaaacctc caccgccatc gccgatatcc acatgctcga cagcggctat
    19081 tcccgcgaag cgcgttccct gctgtaccag gcctaccggc acgagccgac attcggctac
    19141 ctgttcgagt cggagcgccc aggctatgaa cagcgcgtgc gcgccacggt gcgggaactg
    19201 gtcaagcaac acttcctgca ggacttgccg gccattggcc tgctggtcaa cgaccgcttg
    19261 atcggcatcg ccctgatcgc gccgccgcaa cggcggctgg gcatcaccga aagttgggcc
    19321 tggcgcttgc ggatggtgct cagcaccggt tttcgctgca cccgccgcta ccttgagtat
    19381 cacgatgcgg tcgcggcgtg cgtgccgtcg gattcggtgc atgtcctgcc gttgctgggg
    19441 gtccatccgc aattccaggg caaacacttt ggcgagcagc tgctgcaagc ggtgcataac
    19501 tggtgcgcgg tggatgaaca ctctcagggg gtaattctcg acaccggcaa tccgcgctac
    19561 ctggagtttt acaagcgtca gggctatgag gaaattggag aggtggccgt aggaccgatc
    19621 cgcgagcacg tatttttcca ccccaaccct caagtcgtgc agagcgccac ggcataagag
    19681 cgagaacttc tcggccgcgc caggctctat cacgctccca tgttgatcaa ccatgcacgt
    19741 gatagcatcc gcgcctatga agtttccagg aagaattacc agtggcgtgc tcatgctgat
    19801 cagcagctgc gcggcactgg cccaaagtga attggatgtg cggatcaaac cgtccaacga
    19861 tgcactgaaa gccaatatag agggctatat cggcagtctc ggcgatcgtg acgaagaggc
    19921 cttgctgcgc ttcagtcggg gtgccgaaga gcaggcgcgc aaggccgccc aggccctggg
    19981 ttattaccag ccgcagatcg acagcaaggt gacgggaggc aagaccccgc acctgatcct
    20041 cgacatcgac cccggcgagc cggtgcattt gcgcaacgtc actatccgtg tcgatggccc
    20101 ggcggcctcc ctcaaatcct ttcgtgtgcc caagagccat gccttgcaaa ccggtgcggt
    20161 gctcaaccat ggccaatacg atgacgccaa gcggctgatc cagaaccagg cctcgcgcta
    20221 cggctttttc agcggccatt tcacccgctc gaagctgtcg gtcgaccccc gggccggcgt
    20281 ggccgatatc gagttgatct atgacagcgg cccgcgttac tcgctgggca agatcagttt
    20341 cgaaggcgat accccgttcg acgaagacct gctgcaacgc atggtgccgt tcaaggaagg
    20401 tacgccgtat gactcggagc tgatcgccga actcagccag gcgatgcagt cgagcgggta
    20461 tttcgaaagc gtgcgggtcg atgccgcgcc gacagcctcg aaaaacaatg tgatccccgt
    20521 cgacgtcaag cttgaaaccc gcaagccgcg caccatgggg ctgggccttg ggtactccac
    20581 cgacgtcggt ccgcggatca aggccaactg gacccggcac tgggtcaatc cgcaggggca
    20641 tagctatggc tgggagaccg aagtctctgc gccacggcaa aacgtcgggg tgttctacga
    20701 catcccgctg gacccgccgc tgaccgacaa actgcgtttc gccggcggct atcagaacga
    20761 ggaaatcgcc gacaaggaca gcctcagcaa actgctgacg gtggggccgg aatggcacag
    20821 caagttgccc agcggctggc agcgggtggt gtcgctgaag tggcaacgcg aggaatatcg
    20881 gctgggcgac gactccgggc tcagtacgtt gttgatgccc ggcgtgagct atacgtacct
    20941 caagagtgac aatcgcatcg atccacacaa cggctatcgc ctggcatttg aaacccgcgt
    21001 ggccaaggaa ggcttgggtt cggacaacaa cttgctgtac ggcacggcac tggtcaaagg
    21061 cttgaccacg gtcttcgaca agcaccgctt cctcggtcgg gtgcaggtcg gcggcagtgc
    21121 caccaacggc tatacgtcgg tgccgccgtc gctgcggttt ttcgccggtg gcgaccagag
    21181 cgtgcgcggt tacgattatc agagcctgtc cccggaaaac aaccagggcg accgcatcgg
    21241 cggccggtac atggtcgcgg gcagcgtcga atatcaatat tcggtcgccg agaaatggcg
    21301 ggtcgccacg ttcgtcgacc agggcaatgc cttcaatacc ctcgaactgc cgagcctcaa
    21361 gaccggcgtc ggtatcggcg tgcgctgggt ctcgccggtc gggccgattc gcctcgacct
    21421 ggcccatgcg ctggacgacg atggcggcat ccgattgcac ttttccatgg ggcctgagct
    21481 gtgaagcctg tttttgtaaa gcgtggcctg gcaatcacgc tgctggcgat tctgacgctg
    21541 gtgatgctgc tggttctgac gctggccacg gtgctgggga cggcgacggg cagtcgctgg
    21601 gcgctgggat tcgtcccggg tctgagcctg gacaatttcc agggacgctt gggcgggcag
    21661 tggagtgccg accatgtgct gtggcagcag gacagcagcc gggtcgagct ggaccaggtg
    21721 attttcgcct ggtcgccgtt gtgcctgacg cgcatgacgc tgtgcatcga tcaattgcag
    21781 gccgaccggg tcagcctgca atttgcgccg ggtgtcgaag aagacagcag cgcaccgatc
    21841 agccttccgg atgtgcggct gcccgtggcc ctcgaactgg gcgatgtcaa ggtcggcagc
    21901 ctgctgttca acggcagcga acagctcaag ggcctgcaac tggcggcgca ctggacggcc
    21961 aacggcttgc agatcgactc ggtgagcctg caacgcgacg agctgagcct gaacctgtcc
    22021 ggcctgctgc aacccaccgg ccactggccg ctcaaggctc aaggcaaact cacgctgcct
    22081 gcgccaggca ccgaaccgtg ggcgctggct ttgaaggtcg atggcgacct gctgaaaacc
    22141 ctgaacctga ccgccgacag cagcggatac ctgaacgggc aactgaccgg cgagctgcaa
    22201 ccgctggtgg aaaacctgcc ggccaaggtg cgtatcaccg ctgacggctt caagcccggc
    22261 gccgatctgc cggacaccct gcaactcaat cagctggaac ttacgggcgc tggcgatctt
    22321 aaaaacggtt accagttgaa cgccaaggcg acgctgcccg ccgaacaggg cccggtcgcg
    22381 ctggcgctac aaggcaaggt cgacgccagc ggcgcgcaga tcgccgcgct ggacctgacg
    22441 gccaacgaca agcaaagcct caagctgacg gggcaactgg actggagcaa aggcttgaat
    22501 gccgaggcca cagtcgattg gctggatttc ccctggcacc gcctctatcc gctgatcgac
    22561 gaaccggaag tcgccttgcg caccttcaag ggcgaagttt cctacaccga cggcaagtac
    22621 ctcggccact tcgacgctaa ggcggacggc ccggccgggg cgttcagcct gagcagcccg
    22681 ttcgccggcg acctgacgaa aatctacctg caacagattc aactgactgc ggggcagggt
    22741 aaggccgaag ggcacctgaa cctgcaattc gccgacggca tcgcctggga caccgcgctg
    22801 gacctgtcgg cgatcaaccc ggcgtactgg gtcgcggagc tgccgggcac cctcgccgga
    22861 ccgttgcgca gcaaaggcga aatgaagaat gagaaactca gcctgaccgc cgacctcgac
    22921 ctcaagggca agttgcgtgg ccagccggcc gtcctgcaag ccaaggccga tggtggcggc
    22981 gagcaatgga acctcaatgc cctgcaaatc cgcctgggcg acaacagcat ccatggcaag
    23041 ggcagcctgc aacagaaact ggccgggcag atcgacatca agttgccgcg actggcccag
    23101 ctctggccgc aattacgcgg ccagatcaat ggccgggtcg acgtcgccgg cacgctcaag
    23161 gcgccccagg gcaagctcgg gctgcaaggt tcgcaactgg catttgctga taatcgcctg
    23221 caaagcctga acctggatgc caccctcgac agtgcgcaac gggcgaaaat cgacctc
//
