LOCUS       NZ_CABIWO010000002     21661 bp    DNA     linear   CON 29-FEB-2024
DEFINITION  Paraclostridium bifermentans isolate MGYG-HGUT-00024, whole genome
            shotgun sequence.
ACCESSION   NZ_CABIWO010000002
VERSION     NZ_CABIWO010000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paraclostridium bifermentans
  ORGANISM  Paraclostridium bifermentans
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Paraclostridium.
REFERENCE   1
  CONSRTM   EMBL-EBI Metagenomics Team
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2019) EMG, The European Bioinformatics Institute
            (EMBL-EBI), Wellcome Genome Campus, CB10 1SD, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/29/2024 00:21:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,602
            CDSs (total)                      :: 3,499
            Genes (coding)                    :: 3,477
            CDSs (with protein)               :: 3,477
            Genes (RNA)                       :: 103
            rRNAs                             :: 11, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 5, 2 (5S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 22
            CDSs (without protein)            :: 22
            Pseudo Genes (ambiguous residues) :: 0 of 22
            Pseudo Genes (frameshifted)       :: 2 of 22
            Pseudo Genes (incomplete)         :: 13 of 22
            Pseudo Genes (internal stop)      :: 7 of 22
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:03:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 153965
            Orig. end                         :: 175626
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CABIWO010000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21661
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..21661
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21661
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11661](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11661
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     gene            complement(63..440)
                     /locus_tag="FY209_RS11340"
     CDS             complement(63..440)
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592116.1"
                     /locus_tag="FY209_RS11340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_035116861.1"
                     /transl_table=11
                     /translation="MFLVLLGFFSGIIGGMGMGGGTILIPALILFANIDPKIAQSINLL
                     SSIPMTIFALLIHIKNKKVILKLVIPIASFGILGAIFGSFLATYLSSEILKKVFGVFLL
                     VIGVLEVKKGIFNPNKNKCEK"
     gene            complement(440..808)
                     /locus_tag="FY209_RS11345"
     CDS             complement(440..808)
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592117.1"
                     /locus_tag="FY209_RS11345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_207737925.1"
                     /transl_table=11
                     /translation="MKKKFLNFNIKNSFIGLITGFINGVFGSGGGTLLVPILNNILKVE
                     EHKSHATALAIILFLTTTSSFIYVSQGTYDLNTTFKVAVGSIVGGIVGAKILCKLTGRF
                     LRISFGSIMIIAALRMVF"
     gene            917..1672
                     /gene="nadE"
                     /locus_tag="FY209_RS11350"
     CDS             917..1672
                     /EC_number="6.3.1.5"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008795 - NAD+ synthase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nadE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /locus_tag="FY209_RS11350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(+) synthase"
                     /protein_id="WP_035116858.1"
                     /transl_table=11
                     /translation="MTDINFKIDKTIDWLREKVKESNTNGLIVGVSGGIDSAVVAYLIK
                     KAFPKDSMGVIMSIKSNPQDRLDALKVIDGCEIEYLDLDLTDEQVGIYNKVTDGLKNKG
                     LYKENNDRMSDANLRARIRMSTVYTVANNLGYLVVGTDNAAEIHTGYFTKYGDGGVDLV
                     PLANLTKREVYEWAKALGVHNDVINKAPSAGLWEGQTDENEMGTSYDMIDAVVKGEIEK
                     VPQKDQDIIARLHRISEHKRHTAAAPPKF"
     gene            1830..2552
                     /locus_tag="FY209_RS11355"
     CDS             1830..2552
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005365233.1"
                     /locus_tag="FY209_RS11355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_053832153.1"
                     /transl_table=11
                     /translation="MGRIGNIINKKGKQDAKRAKIFTKHARAIAVAAKEGGGNPEYNAT
                     LKAAIDKAKADNMPNDNIDRAIAKGAGGGANENFETIVYEGYGPGGVAVIVETLTDNKN
                     RTAGNVRYYFDKNGGNLGTSGCVSFMFDRKGQILIEATDDVSEEELMDIALEAGAEDLI
                     VEEDGFEVVTSPEDFQAVRDELEAKGYNFISAEVKLLPQTTTKLTEEEQLKFMNRLVDM
                     LEDDDDVQSIAHNWEIEE"
     gene            complement(2581..2904)
                     /locus_tag="FY209_RS11360"
     CDS             complement(2581..2904)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /locus_tag="FY209_RS11360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1540 domain-containing protein"
                     /protein_id="WP_114542281.1"
                     /transl_table=11
                     /translation="MDKIKCSVDNCSHNSKGLCYADRVNIQGSAAQTKEHTACASFLEH
                     AVYSDLTNNTNDSGACSCLFCKVNTCSYNSNNLCTLDSIKVSPDTGRPNLYSETSCSSF
                     KCK"
     gene            complement(3004..3321)
                     /locus_tag="FY209_RS11365"
     CDS             complement(3004..3321)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FY209_RS11365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_114542280.1"
                     /transl_table=11
                     /translation="MSIDKELLSRVEFIEFKQQVLLLKHPSHKATVFAELTLYEFLSIR
                     DYVENFEYYLENGHKFDFKSFESGLYDLIPKLKAYPESSVLISKILMNISNFNKLFDSN
                     N"
     gene            3492..4091
                     /locus_tag="FY209_RS11370"
     CDS             3492..4091
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FY209_RS11370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_021431775.1"
                     /transl_table=11
                     /translation="MFEKKKEFPWRIPIVIILGIVVLAGGIYVGFKSTNENISKKTNSE
                     QKKEETTAKEIFNLSEDCEIWVEKTLEDGTPSKEAPTMIGTIPKDLVGKSKEDITKYLS
                     TKYPNRSIKKLDTYEITLQERETFNDTSKANQFAIVDNKGLLNVYKYNEKGDREFIENT
                     EIETESLPKKVQEEVKSGIFAKSQDEIYSKLEDFGS"
     gene            4228..4737
                     /gene="ruvC"
                     /locus_tag="FY209_RS11375"
     CDS             4228..4737
                     /EC_number="3.1.21.10"
                     /GO_function="GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="ruvC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /locus_tag="FY209_RS11375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="WP_021428405.1"
                     /transl_table=11
                     /translation="MIILGIDPGIAIVGYGIIEYKNNKFRVIDYGAVTTPAHMDILRRL
                     ELVYKGIDMLIKNYNIDEVGIEELFFNKNVKTAITVAQARGVTMLACAHNNIPVYEYTP
                     LQVKQGVVGYGRAQKAQVQQMVKSFLNLKAIPKPDDVADALAVAICHCHSNKLEKTLKN
                     IGGQYV"
     gene            4730..5332
                     /gene="ruvA"
                     /locus_tag="FY209_RS11380"
     CDS             4730..5332
                     /EC_number="3.6.4.12"
                     /GO_component="GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA]"
                     /GO_function="GO:0009378 - four-way junction helicase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="ruvA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /locus_tag="FY209_RS11380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="WP_148551431.1"
                     /transl_table=11
                     /translation="MYSYIKGKIEEINLDSLVIEANNIGYKVNVSANTLADVKLGKECK
                     IHTKLIVREDDMSLCGFSTKEELKMFELLNSVSKIGPKVALGILSFATPKQIGAYIVSE
                     DVAKMSKAPGVGKKTAERIILELKDKIDKNNIEFEPTLLSQIPIAISQDEAVDALIALG
                     YSSQESKEAVDKCKKDGMNTEDIIKKSLSYIMSKSLR"
     gene            5349..6362
                     /gene="ruvB"
                     /locus_tag="FY209_RS11385"
     CDS             5349..6362
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0009378 - four-way junction helicase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="ruvB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286274.1"
                     /locus_tag="FY209_RS11385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="WP_021428482.1"
                     /transl_table=11
                     /translation="MFEDENRIITSSMQNEDVDIENNLRPKSLDDYLGQNKAKELLKIF
                     IEAAKARNEQLDHVLLYGPPGLGKTTLASIIASEMGVNLRITSGPAIERAGDLAAILTN
                     LNENDVLFIDEVHRISRTVEEVLYSAMEDYCLDIIIGKGPSARSIRLDLPKFTLIGATT
                     KAGMLTNPLRDRFGVICKLDYYTVEELAQIVIRSSAILGAEIQIGGATEIARRSRGTPR
                     IANRLLKRVRDYAQVRADGNITDEVANDALELLGVDSLGLDYVDEKLLVTIIEKFKGGP
                     VGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRIAMPLAYEHLNIPYPKEK"
     gene            6468..7493
                     /gene="queA"
                     /locus_tag="FY209_RS11390"
     CDS             6468..7493
                     /EC_number="2.4.99.17"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="queA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /locus_tag="FY209_RS11390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="WP_021428515.1"
                     /transl_table=11
                     /translation="MKTSDFYFDLPEELIAQTPLEDRSNSRLMVLDRKTGDVEHKIFKD
                     VIDYLNPGDCLVLNNTRVIPARLIGEKVDTGGKIEFLLLKRTEKDVWQALVKPGKRAKI
                     GTKFSFGNGKLIGEVVGLAEEGSRLVKFYYEGIFEEVLDELGNMPLPPYITERLEERER
                     YQTVYSKHNGSAAAPTAGLHFTNELLESIKAKGIDIAFVTLHVGLGTFRPVKVDDVLAH
                     EMHSEYYMVDKEAAEKINRAKKNGNKVICVGTTSCRTVESASNENGEIVESSGWTNIFI
                     YPGYKFKVVDRLITNFHLPESTLIMLVSALVSKDAVLNAYNTAVKEKYRFFSFGDAMII
                     K"
     gene            7513..8013
                     /locus_tag="FY209_RS11395"
     CDS             7513..8013
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /locus_tag="FY209_RS11395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphate-starvation-inducible PsiE family
                     protein"
                     /protein_id="WP_021428403.1"
                     /transl_table=11
                     /translation="MKKLAEKSLALKIAYIFESLLAMVVLLAVFLGTIDVLRMIWHSYI
                     VEYRTPVQYAQFNDLLGQILLLVIGVELVVMLSLHIPGALIEVLLYAIARKLLLLPKSE
                     GMLELLLGIMAIAGLFAIRKYLLTDDNSTMNVTSIHYEECEDEDCDCHKRNLEKALKNE
                     NKQ"
     gene            8033..9154
                     /gene="tgt"
                     /locus_tag="FY209_RS11400"
     CDS             8033..9154
                     /EC_number="2.4.2.29"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tgt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) bTGT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /locus_tag="FY209_RS11400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="WP_021428401.1"
                     /sec_met_domain="bTGT (E-value: 1.6e-208, bitscore: 686.1,
                     seeds: 1816, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVRYELIKTCKQSGARLGRLHTPHGVIETPIFMPVGTQATVKS
                     MTPEELKEIGSQIILSNTYHLYMRPGHDLVKEAGGLHKFMNWDKPILTDSGGFQVFSLG
                     PLRKITEEGVNFRSHIDGSKHFISPEKAMEIQNALGSDIMMAFDECAPYPADREYVKNS
                     LERTTRWLERCKEAHKNTENQALFGIIQGGMYKDLREQSAREVLALDLPGYAVGGLSVG
                     EPKDLMYEVLDYTVPLMPEDKPRYLMGVGSPDDLIEGVIRGIDMFDCVLPTRIARNGTA
                     MTSEGKVVVRNAKYARDFGPLDPNCDCYCCRNYTRAYIRHLVKANEILAARLITTHNLH
                     FLLDLMKQVRQAIMEDRLLDFRKEFFQKYGYEL"
     misc_feature    complement(9165..9178)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.88"
                     /tool="antismash"
     gene            9233..9505
                     /gene="yajC"
                     /locus_tag="FY209_RS11405"
     CDS             9233..9505
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="yajC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /locus_tag="FY209_RS11405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="preprotein translocase subunit YajC"
                     /protein_id="WP_021428480.1"
                     /transl_table=11
                     /translation="MPQAVVGILMWVVFFAIFYFFLIRPQKKKDKQLKEMRESLDVGAK
                     VVTIGGIVANVAKVEEDVVILEIGPSRTKVPFEKWAIASTESKEK"
     gene            9571..9933
                     /locus_tag="FY209_RS11410"
     CDS             9571..9933
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /locus_tag="FY209_RS11410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR04086 family membrane protein"
                     /protein_id="WP_148551432.1"
                     /transl_table=11
                     /translation="MEKSNSIFKGLGYAYIITLICLLTYNGLLTFTNMSGDSIAMAASI
                     ITTASAAFGGFYASKKIKEKGLLYGILVGLLYIVCLMVVVFLAKDSFVFEITSIYKVLL
                     TSLAGGIGGVLGVNFK"
     gene            10001..10144
                     /gene="scfA"
                     /locus_tag="FY209_RS11415"
     CDS             10001..10144
                     /codon_start=1
                     /gene="scfA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /locus_tag="FY209_RS11415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="WP_021122491.1"
                     /sec_met_domain="TIGR03973 (E-value: 4.6e-26, bitscore:
                     84.6, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.6e-26, bitscore: 86.1,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKHIKTLSKATLKESAAKGGCGECQTSCQSACKTSCTVANQEC
                     ER"
     gene            10288..11661
                     /gene="scfB"
                     /locus_tag="FY209_RS11420"
     CDS             10288..11661
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="scfB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019595258.1"
                     /locus_tag="FY209_RS11420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="WP_085283014.1"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1e-29,
                     bitscore: 96.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.4e-07, bitscore: 24.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 5e-73, bitscore:
                     240.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.1e-17, bitscore: 56.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 9e-16, bitscore: 52.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 7.8e-22, bitscore:
                     71.7, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.2e-07, bitscore: 25.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDMIHKFSMHGYNIVLDVNGGAVHVVDEVAYNLLDHYKEKSLDEI
                     ISLLSETYTEDQIKEAYNEVKTLEEEGLLYTEDTYNHHPNFIDRKKVVKALCLHVAHDC
                     NLKCKYCFAAQGDFGGAKELMSYEVGKKAIDYLIANSGNRRNLEIDFFGGEPLMNFEVV
                     KQLVEYGRSIEKENNKNIRFTITTNGILLDDEKIEYINKHMHNVVLSLDGRKDVNDRMR
                     PTLNDKGSYDIIMPKFKKLVESRPKDKYYYIRGTFTRDNLDFSEDVLHFADEGFELTSV
                     EPVVDDESNPFALREEDLETVFNEYEKLAVKYSDRLLNGDKFKFFHFMIDLNQGPCVIK
                     RITGCGAGNEYLAITPEGDMYPCHQFVGKEEFKLANINDEEIVIPRELTDKFKNAHVYS
                     KEDCKKCWNKFYCSGGCHANAMNFNGDVMKPYELGCEMQKKRTECSIMIQARLMIEGK"
     aSDomain        10291..10584
                     /aSDomain="Ranthipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a
                     ranthipeptide/SCIFF cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FY209_RS11420_Ranthipeptide_rSAM_RRE.
                     1"
                     /evalue="1.00E-30"
                     /identifier="RREFam024.1"
                     /label="FY209_RS11420"
                     /locus_tag="FY209_RS11420"
                     /protein_end="99"
                     /protein_start="1"
                     /score="96.9"
                     /tool="antismash"
                     /translation="DMIHKFSMHGYNIVLDVNGGAVHVVDEVAYNLLDHYKEKSLDEII
                     SLLSETYTEDQIKEAYNEVKTLEEEGLLYTEDTYNHHPNFIDRKKVVKALCLH"
     gene            11667..12167
                     /locus_tag="FY209_RS11425"
     CDS             11667..12167
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440863.1"
                     /locus_tag="FY209_RS11425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="WP_021428394.1"
                     /transl_table=11
                     /translation="MIKGYKGNNPVIDSSVFIAESADIIGNVTIGKNSNVWYNVVIRGD
                     ENNIVIGENTNIQDGTVIHIEYNKDTVIGNNVTVGHKALIHGCTIGDNTLIGMGSIILG
                     GVEIGEYTLVAAGSLIPPNKKIPSGVLVKGAPAQVVRELTEEEKQNLVNSALKYVETAN
                     NYK"
     misc_feature    12168..12184
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.1"
                     /tool="antismash"
     gene            12253..13917
                     /locus_tag="FY209_RS11430"
     CDS             12253..13917
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440864.1"
                     /locus_tag="FY209_RS11430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="WP_148551433.1"
                     /transl_table=11
                     /translation="MKVSYRHLKRYKEIVHILLKYGFSIIVEKLNIEGVAYKIPITNPP
                     AEIKNMTTGERLRKAFEELGPTYVKLGQILSTRKDLLDQSIISELVKLRDNVEVFDTEI
                     AMSILKEELSMPIDKIFEEFNETPIAAASLGQVYEAKLISGENVIVKIQRPNVEQLIKS
                     DVEILKSIASALTDIKKDLNIDVQGIVEDFETQILRELDYNFEAINAVKFQNMFSNTNE
                     VYIPKVFMDYTTQKVLVLEKIVGVKLSDVNKMKKLGWDTEKISEIGIRSLFKQIFEYGF
                     FHADPHPGNIFVINENCIAYIDFGMIGIIDKKMLNTLNSITLAAVDRNIDRIIYLLMEL
                     DVISYDTNLTGLRQDLLYLMHYYYDVPIDKLSLGDILNEVFRFCRTYKAALPPQLVLLG
                     KALITLEGTARELNPNFSITVAGKSFMKYYYLNRLNPENLIKESKQSAQEAIADIRIIP
                     RQVKSILRNIEKNNIKIHIEDVKFSKLEKIITDLATQLSLSLVLAALLVGSSLIIASPN
                     VNSNWWVKVLAFSGFVVSFLVGILLVVKIIRSQYIKK"
     gene            13930..16374
                     /gene="recJ"
                     /locus_tag="FY209_RS11435"
     CDS             13930..16374
                     /GO_function="GO:0008297 - single-stranded DNA
                     exodeoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592139.1"
                     /locus_tag="FY209_RS11435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="WP_148551434.1"
                     /transl_table=11
                     /translation="MFNKKWTLKYKGSIKEYDLGKKMKISPEIGQILKNRGIKDKEDAE
                     IFINPSLDYLRDPFLMKDMKKAVDRIKDAMENKQNIWVYGDYDVDGVSSTSILCIYFDS
                     IGYPVKYYIPNRLEEGYGINEDAIRVLKEQECDLIISVDCGITSVKEVELANELGIDII
                     ITDHHEVQDKIPDAYAVINPKQRDCNYPFDMLCGCGVAFKIIQALTPEDEFKTSMYKYL
                     EIVTLATICDIVPLVDENRIIVKNGLRLMKDGENIGLRELINVCGIETDKIGSSHIGFS
                     IGPRINASGRLGYSYLGVELFTTKSKEEAMEIASLLEEKNNERQMIEAKMYQEAENIIL
                     NDKNYNSDKVLVIAKEGWQHGVIGIVASKLTEKYYKPTILLTIEDGEATGSARSIKGFS
                     IFDTLVNCSELLNKFGGHEQAAGLSMDSKNIETLRRKVNEIANYQLTEDDMVENISVEF
                     ELNEGSIDFNLIEELHSLEPFGMSNPSPRFIMRELEIRGIFRLGKDKNHLKLNLEKNNV
                     YECIGFNMAYMSEQFEVGDKVDVLFQLDENNYMGNRKIQFLLKDIRMAYPKDIGKSLDS
                     INLFRNIKPCLDSNNKISNYGKVNIDGCKAINVFDYINEKSLVIANSVNGFFKALSDIS
                     LTEYEFDINYNIIENINNKVQLIFFPYIDKIDLKRYNNIILYDYLYDIEEYSCLFEESD
                     NECEIIKYYDKNDLIYINNIIRSIIPEREEFITLYKIMSKYKEIKINILDIKSKLNIAP
                     IKLFAMLNVLKELDLINFHVEDENSTLTMEIMPKPSTKIDLASSKVLQGLNQLKDKYKQ
                     SY"
     gene            16385..16897
                     /locus_tag="FY209_RS11440"
     CDS             16385..16897
                     /EC_number="2.4.2.7"
                     /GO_function="GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006168 - adenine salvage [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /locus_tag="FY209_RS11440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="WP_021428377.1"
                     /transl_table=11
                     /translation="MNLKDSIREIKDFPKPGIGFKDITTLLSNGEAFKFAVDEIIADLK
                     DKNVDIIVGPEARGFLMGTPVAYGMGIGFVPVRKPGKLPGETEKFEYGLEYGTDTLEIH
                     KDSIKPGQRVAIVDDLLATGGTMEAAAKLIEKLGGEVVSMQFLIELEELNGRDKVSQYH
                     VNSLVKY"
     gene            16972..19179
                     /locus_tag="FY209_RS11445"
     CDS             16972..19179
                     /EC_number="2.7.6.5"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422921.1"
                     /locus_tag="FY209_RS11445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="WP_114542966.1"
                     /transl_table=11
                     /translation="MQDKQLQELIEKIKRYAPNGDLDLIEKAYYYGKKAHEGQLRKSGE
                     PYFIHPIAVANILCDMELDMQTIAAGLLHDVVEDTEFTYEDIKNDFGEEIADLVDGVTK
                     LGQIKYKSKEETQAENLRKMFLAMSKDIRVILIKLADRLHNMRTLKFMPPEKAKAKATE
                     TLEIYGGIASRLGIYKVKWELEDIALRYIDSDGYYDLVEKVAKKRSQREAYIERIVHVL
                     KEKFDEVNINCDIYGRPKHFYSIYRKMKNKHKDFEEIYDLMAVRIIVNSVKDCYAVLGM
                     VHTLWKPIPGRFKDYIAMPKPNMYQSLHTIVVGPDGEPLEIQIRTKEMHNIAEYGIAAH
                     WKYKEGKTSVKESKLEEKLQWLRQMMEWEKDLKDPQEFMDALKDDVFNSQVYVFTPKGD
                     VIELPAGSTPIDFAYRVHTNVGNKCVGAKINGRIVTLDYKLQNGNIVEILTSANSSGPS
                     RDWINIVQTPNAKSKIRQWFKKERREENIERGNLILEKEFKKYSIPTKDPIIEKYMLQM
                     ARKFNQPTVGDLVATIGYGGIMPSQIVPKVKELYEKDHVKKSSEIKVIDDINKHSIGEQ
                     EYTKKRKKSSPQGIIVKGVDNILVRFAKCCNPIPGDEIIGYITKGRGVAVHRKDCPNSN
                     LDNEYFRNRLVEVSWENSNNAKFEAEIQIQAEDRRGIINDITHIVSIEKVSLNGINARK
                     GKLNIVSVNLLVEVDSIETLTLLMKKVRAIPGVEDIYRVIN"
     gene            19189..19638
                     /gene="dtd"
                     /locus_tag="FY209_RS11450"
     CDS             19189..19638
                     /EC_number="3.1.1.96"
                     /GO_function="GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dtd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426448.1"
                     /locus_tag="FY209_RS11450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="WP_035116838.1"
                     /transl_table=11
                     /translation="MRAVVQRVASSSVTVDEQKISNIEKGLLVLLGVTHEDTSKDVDYL
                     IEKIVNLRIFEDEDEKMNLSLKDINGELIVVSQFTLYGDCKKGRRPNFTGAAKPDLANN
                     LYEEFIEKAKKQNINVGTGKFGAHMMVELINDGPVTILIDSEKNF"
     gene            19652..20269
                     /locus_tag="FY209_RS11455"
     CDS             19652..20269
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /locus_tag="FY209_RS11455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_114542965.1"
                     /transl_table=11
                     /translation="MIIEKFTDHLFGENTYLIADKNTREGAVIDPGGEVDDLMRFIKDN
                     FIDVKYIILTHGHGDHIGCVPKLKETTNACIIADSEEKELLLDKKKNLSYKMHCGATEF
                     DADKYVNEGDSIKLGELKLKFIHTPGHTKGCMCIKVGNHMFTGDTLFAGSMGRTDLYSG
                     DDNQMKKSLNRLKKYEDDIIVYPGHGPNTTMGIEKATNPYLV"
     misc_feature    complement(20837..20851)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.05"
                     /tool="antismash"
     misc_feature    20839..20853
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 19.55"
                     /tool="antismash"
     misc_feature    21333..21350
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
ORIGIN
        1 agtgatacta taaaaaaatg cccaaagtta attttataaa aattaaactt tgggctattt
       61 tgttactttt cacatttatt tttatttgga ttaaaaatgc cttttttaac ttctaaaact
      121 cctattacaa gtaaaaaaac tccaaaaact ttttttaaaa tttctgatga taggtatgtt
      181 gctaaaaaag atccaaatat agctcctaaa ataccaaatg aggctattgg tattactaat
      241 tttaaaataa cctttttatt ttttatatgt atcaataaag cgaatatagt cataggtatg
      301 gatgaaagta aatttatact ttgagctatt ttagggtcaa tatttgcaaa taatattaat
      361 gctggaatca atattgtacc gccacccata cccataccac ctattattcc agaaaaaaat
      421 ccaagtaaaa caagaaacat taaaacacca tccttaatgc agctataatc attatagatc
      481 caaaagatat tcttaaaaat cttccagtca acttgcaaag tattttagcg ccaacaatgc
      541 cgccaacaat acttcctaca gcaactttaa aagttgtatt taaatcatag gtaccttgag
      601 aaacatatat aaaggaactt gtagttgtta aaaataatat tattgcaagc gctgtagcat
      661 gagacttatg ttcttctact tttaaaatgt tatttaaaat aggaactaaa agtgttccac
      721 caccagatcc aaaaacaccg tttataaagc ctgttattaa acctataaat gaatttttaa
      781 tattaaaatt taaaaatttt tttttcataa tatcaccttc ttgaattatt tttaacataa
      841 agcataaatt atatttaatt aaaataaaaa tatctgatat aattgggtta tccataaaat
      901 gtaaggagga agtataatga cagatataaa ttttaaaata gataaaacaa tagattggtt
      961 aagagaaaaa gtaaaagaat caaatactaa tggtttaata gtaggtgtgt ctgggggtat
     1021 agactcggca gtagttgctt accttataaa aaaagctttt ccaaaagatt caatgggtgt
     1081 aattatgagc ataaaaagta atccacaaga tagattagat gcactaaaag taatagatgg
     1141 ttgtgaaata gagtatttag acttagattt aacggatgaa caagttggaa tatataataa
     1201 agttactgat ggtttaaaaa acaagggact ttataaagaa aataatgata gaatgagtga
     1261 tgctaactta agagctagaa taagaatgag tacagtgtat acagttgcaa ataatttagg
     1321 gtatttagtt gtaggaactg ataacgcagc agaaattcat acagggtatt ttactaagta
     1381 tggagatgga ggagttgatt tagttcctct agcaaactta acaaaaagag aagtatatga
     1441 atgggctaaa gctttaggtg ttcataatga tgttataaat aaagccccat cagctgggct
     1501 ttgggaaggt caaactgatg aaaatgaaat gggtacaagc tatgatatga tagatgctgt
     1561 agtaaaaggt gaaatagaaa aagttcctca aaaagaccaa gatataatag caagacttca
     1621 tagaattagt gaacataaaa gacatacagc agcagcaccg cctaagttct aatttactaa
     1681 attaatgttt tatgctaaaa ttacggtgta tatatagtat aacttacaac atgtttatat
     1741 agtaaagtta tattacgtat taaatatcct tatataaaat ataagcataa cgtaacttta
     1801 ttttaattta catagcaagg agtggaatta tgggacgtat aggaaacata atcaacaaaa
     1861 aaggtaaaca agacgctaag agagcaaaaa tatttacaaa acatgcaaga gctatagcag
     1921 ttgcagctaa agaaggtgga ggaaatccag aatacaatgc aacactaaaa gcagcaatag
     1981 ataaagctaa agcagataat atgcctaatg ataatataga tagagctata gctaaaggtg
     2041 ctggtggtgg agccaacgaa aactttgaaa ctatagttta tgaagggtac ggaccaggag
     2101 gagttgcggt aatagtagaa actttaactg acaacaaaaa cagaacagca ggaaatgtta
     2161 gatactactt cgataaaaat ggtggaaact taggaactag tggatgcgtt tcatttatgt
     2221 ttgatagaaa aggtcaaata ttaatcgaag caactgatga tgtatctgaa gaagagttaa
     2281 tggatatagc attagaagct ggagctgaag atctaatagt tgaagaagat ggatttgaag
     2341 tagtaacttc tccagaagat ttccaagctg ttagagacga attagaagct aaaggatata
     2401 actttatatc agcagaagtt aaattattac cacaaacaac tactaaatta acagaagaag
     2461 aacaattaaa gttcatgaat agattagtag acatgctaga agatgatgat gatgttcaat
     2521 ctatagctca taactgggaa atagaagaat aaaaaaagga gatatttata tctccttttt
     2581 ttatttacat ttaaaacttg aacaacttgt ttcagagtaa aggttaggtc taccagtatc
     2641 aggcgatact tttatagaat ctaaagtaca taagttgttt gagttgtatg aacatgtatt
     2701 caccttacag aaaaggcaag agcacgctcc actatcattg gtattattag taagatcact
     2761 ataaactgca tgttctaaaa atgatgcaca tgctgtatgt tcttttgttt gagctgcact
     2821 tccttgaatg ttaactctat ctgcgtaaca taaacctttg ctattgtgag aacagttatc
     2881 aacactacat ttaattttat ccataataaa tcctcctaaa atagtattta ctaaaattat
     2941 ttccaaaagg atttatagat atactttata aaaaaaggca atagagattt taaagtcata
     3001 tcactaatta tttgaatcaa ataatttatt gaagtttgat atattcatta gtatttttga
     3061 aattaaaact gaactttctg gataagcttt tagtttaggt attaaatcat ataagcccga
     3121 ttcaaagctc ttaaaatcaa atttatgtcc attttctaaa taatactcaa aattttcaac
     3181 ataatctcta atagataaaa attcgtataa agttagctct gcaaatacag tagctttatg
     3241 agacgggtgt tttaacagta aaacttgttg tttaaactca ataaattcaa ctcttgataa
     3301 taattcctta tcgatactca atattttcac ctccatcaaa aaatcatatt tataaagtat
     3361 aatatgaaaa tttatcaata aatgggacta aggatagaaa aatatttaaa ataaaatatt
     3421 ataataaatg taaaaaatgt ataaaaaata aacaattgga aaaaatatcc gatataagga
     3481 ggttgttttt aatgttcgaa aagaaaaaag aatttccttg gcgaatacca attgttataa
     3541 ttttaggcat agtagttctc gctggaggga tttatgtagg atttaaatca acaaatgaaa
     3601 atatttctaa aaagaccaat tcagagcaaa agaaagaaga aacaacagca aaagaaattt
     3661 ttaatttaag tgaagactgt gaaatttggg tagaaaagac acttgaagat ggcacaccta
     3721 gcaaagaagc tccaacaatg atcggtacga taccgaaaga tttggttgga aaatcaaaag
     3781 aagatataac taagtactta tcgactaaat atcctaatag aagcataaaa aaactagata
     3841 catatgaaat tactttacaa gaaagagaaa catttaatga tactagtaag gctaatcaat
     3901 ttgctatagt tgataacaaa ggtttattaa atgtttacaa gtacaatgaa aaaggcgata
     3961 gagaatttat agaaaataca gaaattgaaa cagagtcttt acctaaaaaa gttcaagaag
     4021 aagttaaatc tggaatattt gcaaaatcac aagatgaaat ttattcaaaa ttagaagact
     4081 ttggaagttg aaaaaatata aacttataac caatactatt gaaagagatg aaagggaaac
     4141 ttttcatctc tttatagttt atagctaaat atgttattat atattaatat agaacgtaag
     4201 tttcgtaaaa aggagttatt tcaaaatatg attattttag gtatagatcc aggaattgct
     4261 attgttggtt atggaattat agaatataaa aataataagt tcagagttat tgattatgga
     4321 gcggttacta ctccagcaca catggatata ttaagaagat tagagcttgt atataaagga
     4381 atagacatgc ttataaaaaa ttataatatt gatgaagttg gaattgaaga gttgttcttt
     4441 aataaaaatg taaaaacagc tataactgta gcacaagcga gaggagttac aatgcttgca
     4501 tgtgcacata ataacatacc tgtatatgaa tatacacctc ttcaagttaa acaaggagta
     4561 gttggatatg gtagagctca gaaagctcaa gttcaacaaa tggttaagtc atttttaaat
     4621 ttaaaggcga taccaaaacc agatgatgta gcagatgcat tagcagttgc aatatgtcat
     4681 tgtcattcaa ataaattaga aaagacacta aagaacatag gggggcaata tgtatagtta
     4741 tataaaaggt aaaattgaag aaataaactt agatagttta gtaatagagg caaataatat
     4801 tggatataaa gtaaatgtat cagcaaatac tttagcagac gtaaaactag ggaaagaatg
     4861 taaaattcat actaagctaa tagtgagaga agatgacatg agtctatgtg gattttcaac
     4921 aaaagaagag ttaaaaatgt ttgaattatt aaattcagtt tctaaaatag gacctaaggt
     4981 agctttggga attttatcgt ttgctacacc taaacaaata ggtgcatata tagtcagtga
     5041 agatgtagca aaaatgtcaa aagcgccagg ggttgggaaa aaaactgctg aaagaattat
     5101 attagaacta aaagataaaa ttgataaaaa taacatagag tttgaaccta cacttcttag
     5161 ccaaatacca atagctatat cacaagatga agcagttgat gcacttattg cattaggata
     5221 ttcatctcaa gaatctaaag aagcagttga taagtgtaaa aaagatggaa tgaacacaga
     5281 ggatataatt aaaaaatcat taagttatat tatgagcaaa tctcttagat agagggggaa
     5341 attgaaatat gtttgaagat gaaaatagaa ttataacatc atctatgcaa aatgaagatg
     5401 tagacataga aaataattta aggccaaaga gtctagatga ttatttaggt caaaataagg
     5461 caaaagaatt attgaaaata tttatagagg cagcaaaagc tagaaatgaa cagttagacc
     5521 atgttttact atatggacca ccaggtcttg gaaaaacaac acttgcatct ataatagcta
     5581 gcgagatggg agttaatctt agaataacat cagggcctgc tatagaaaga gctggagact
     5641 tagcggctat acttacaaat ttaaatgaaa atgatgtttt atttatagat gaggttcata
     5701 gaataagtag aacagttgaa gaagttttat actctgcaat ggaagattac tgtttagata
     5761 taattatagg taaagggcca tctgcgagaa gtatacgact tgatttacct aaatttacat
     5821 taattggagc aactacaaaa gcaggtatgc taacaaaccc gttaagagat agatttggag
     5881 ttatatgtaa actagattac tatacagttg aagaacttgc tcaaatcgta ataagatcct
     5941 ctgctatttt aggagctgaa attcaaatag gaggagcaac cgagattgca agaaggtcta
     6001 gaggaactcc aagaattgca aatagattac taaaaagagt tagagactat gcacaagtta
     6061 gagcagatgg aaatataact gatgaagttg caaatgatgc tttagaattg ttaggagtag
     6121 atagcttagg acttgactat gttgatgaaa aattactagt tacaataatt gaaaagttta
     6181 agggcgggcc agtaggatta gatacattgg cagcatctat tggagaagat agaaatacta
     6241 ttgaggatgt gtatgaacca tatttacttc aattaggatt tataaataga gggcctagag
     6301 gaaggattgc catgcctctt gcatatgaac atttaaatat tccttatcca aaagaaaaat
     6361 aggaaaaatc aatttatata gcatttaata ataggattaa tgatagaaaa aaattatttt
     6421 ttttgttatg atgtaatttg tactaaaaaa tagaaaggac gtttaaattg aaaactagtg
     6481 atttttactt tgacctacca gaagaattaa tagctcaaac accgttagag gatagatcta
     6541 actctagact tatggtttta gatagaaaaa cgggagatgt ggagcacaaa atatttaaag
     6601 atgttataga ttatctgaat ccaggagact gtttagttct taataataca agagttatac
     6661 cagctagact tataggagaa aaagttgata ctggagggaa aatagaattt cttttattaa
     6721 aaagaacaga aaaagatgta tggcaagctt tagtaaagcc gggaaaaaga gctaaaatag
     6781 ggacaaaatt ttctttcgga aatggaaaac ttataggcga ggttgtaggg cttgcagaag
     6841 aaggttctag attagttaaa ttttactatg aaggaatatt tgaagaagta ctagatgaat
     6901 taggaaatat gccactacct ccatatataa cagaaagatt agaagaaaga gaaagatacc
     6961 aaactgtata ttcaaagcat aatgggtctg cagcagcccc tacagcagga cttcatttca
     7021 ccaatgaatt actagaaagt ataaaagcaa aaggaatcga tatagctttt gtaacattac
     7081 atgtagggct tggaactttt agacctgtaa aagttgatga tgtattagca catgaaatgc
     7141 actctgagta ctatatggtt gataaagaag ctgctgagaa aataaataga gcgaaaaaaa
     7201 atggaaataa agttatatgt gttggtacta ctagttgtag aactgtagaa tcagcaagta
     7261 acgaaaatgg agaaattgta gagtctagtg gatggacgaa tatatttata tatccagggt
     7321 ataagtttaa ggtagtagat agactaataa cgaatttcca tttaccagaa tctactttaa
     7381 taatgttagt aagtgcatta gtttcaaaag atgctgtttt aaatgcatat aatacagcag
     7441 ttaaagaaaa atatagattc tttagttttg gagatgcaat gataattaaa taaattatca
     7501 aggggggata atatgaaaaa actagctgaa aaaagtttag cgcttaaaat cgcatatata
     7561 tttgaatcac tgctagctat ggttgtgctg cttgcggtat ttttaggaac aatagatgta
     7621 ttaagaatga tatggcattc gtatattgtt gaatacagaa ctccagtaca atatgctcag
     7681 tttaatgatt tgttaggaca aatattacta ttagtaatag gtgtagagtt agtagtaatg
     7741 ctttcattac atattccagg ggcgctaatt gaagtactat tgtatgcaat agctagaaag
     7801 ttactattat tgcctaagag tgagggtatg ttagagttat tacttggaat tatggctata
     7861 gctggcctat ttgcaataag aaagtatttg ttaactgatg acaatagcac aatgaatgta
     7921 accagtattc attatgaaga atgtgaagat gaagattgtg attgccataa gcgaaattta
     7981 gaaaaagctt taaaaaatga aaataaacaa tagataaata aggagagtta taatgagtgc
     8041 agtaagatat gaacttataa aaacttgtaa gcaaagtgga gcaagattag gaagattaca
     8101 cactcctcac ggagtaatag aaacaccaat atttatgcca gttggtactc aagcaactgt
     8161 aaaatctatg acaccagaag aattaaaaga aataggttct caaattattt taagtaatac
     8221 atatcattta tatatgagac caggtcatga tttagttaaa gaagcgggag ggcttcataa
     8281 atttatgaac tgggataagc ctatacttac agatagtggt ggattccaag tatttagctt
     8341 agggccactt agaaaaataa ctgaagaagg tgttaacttt agatctcata tagatggatc
     8401 aaagcacttt ataagtccag aaaaagctat ggaaatacaa aatgcattag ggtcagatat
     8461 aatgatggca tttgatgagt gtgctccata tccagctgat agagagtatg taaaaaattc
     8521 tttagaaaga actactagat ggttagaaag atgtaaagaa gctcataaaa atacagaaaa
     8581 tcaagctcta tttggaataa tccaaggagg aatgtacaaa gatttaagag aacaatcagc
     8641 aagagaagtt ctagctttag acttaccagg atatgctgtt ggaggattaa gtgttggaga
     8701 gccaaaagac cttatgtatg aagtgttaga ttacacagta cctttaatgc ctgaagataa
     8761 acctagatat ttaatgggag taggaagtcc tgatgactta atagaaggtg ttataagagg
     8821 aatagatatg tttgactgcg tattacctac tcgtatagct agaaatggta cagctatgac
     8881 aagtgaaggt aaagtagtgg ttagaaatgc aaaatatgca agagattttg gaccattaga
     8941 tccaaattgt gattgttatt gttgtagaaa ctatacaaga gcatatataa gacatttagt
     9001 taaagctaat gaaattttag ctgctagact tataactact cataacttac atttcttact
     9061 agatttaatg aagcaagtaa gacaagcgat aatggaagat agattattag attttagaaa
     9121 agaatttttc caaaaatatg gctatgaatt ataattattt taagttataa taattattat
     9181 ataaaactaa attgaagagt tttaagaata tattataaaa ggagtgggat aaatgcctca
     9241 agcagtagta ggaatactta tgtgggttgt attttttgca attttttatt tcttcttaat
     9301 aagaccacaa aagaaaaaag acaagcaact taaagaaatg agagaaagct tagatgtagg
     9361 cgctaaagtt gttacaatag gtggtatagt agctaatgta gctaaggttg aagaagatgt
     9421 tgttatatta gaaatagggc ctagtagaac aaaagtacca tttgaaaaat gggctatagc
     9481 ttctacagaa tcaaaagaaa aataaaacga tattagtaat tacaaagcct ttccctgaat
     9541 atatcttata ttagagggga ggtttttttt atggaaaaat caaatagcat atttaaagga
     9601 ctcggatatg cgtacataat aacattaatt tgtttactaa cttacaatgg actacttact
     9661 tttactaata tgtctggaga cagcatagct atggctgctt ctattataac tacagcttct
     9721 gctgcatttg gaggatttta tgcatctaaa aaaataaaag aaaaaggtct tttatatggt
     9781 atattagttg gactacttta catagtgtgt ttaatggtag ttgtattttt agctaaagat
     9841 tcttttgtat ttgagattac atctatatat aaagtattat tgacatcact tgcaggtgga
     9901 ataggtggag ttttaggggt aaactttaaa taaatttcca cttatgtaaa atttatgata
     9961 taatcaataa aggtttatat aaggatagga ggtagtttca atggaaaaga agcatataaa
    10021 aactttatct aaagctactt taaaagaaag tgcggcaaaa ggtggatgtg gagaatgtca
    10081 aacatcttgt caatctgctt gtaaaacttc ttgtacagtt gcaaatcaag agtgcgaaag
    10141 atagtaaata tattttaaaa aagaaaaagc agctaattta gctgcttttt ttgagtgaaa
    10201 ttgaatcgat ttgatagaaa agataaatag tacataatta catttatatg ataatatata
    10261 gatataaaca aactaggagg gaccacaatg gatatgatac ataaattttc aatgcacggg
    10321 tataatatag ttttagatgt aaacggtgga gctgttcatg ttgttgatga agttgcatat
    10381 aacctattag accactataa agagaaatct ctagatgaga taataagttt attaagtgag
    10441 acttatacag aagatcaaat caaagaagct tataacgaag taaaaacatt agaagaagaa
    10501 ggtttgttgt atacagaaga cacatacaat catcacccta attttataga tagaaaaaaa
    10561 gtagtcaaag ccttatgctt acatgtggct catgattgta atttaaaatg taagtactgt
    10621 tttgctgcgc aaggagattt tggtggagct aaagaattaa tgagttatga agtaggtaaa
    10681 aaagcaatag attacttaat agctaattct ggaaatagaa gaaacttaga gatagacttc
    10741 tttggtggag agcctctaat gaattttgaa gttgtaaaac aacttgttga atacggaaga
    10801 agtatagaaa aagaaaataa taaaaatata agatttacaa taactacaaa tggaatatta
    10861 ttagatgatg aaaaaataga gtacataaat aaacatatgc ataatgtagt tttaagttta
    10921 gatggaagaa aagatgttaa tgatagaatg agacctacat taaatgacaa aggtagttat
    10981 gatataataa tgcctaagtt taaaaaatta gttgaaagta gacctaaaga caaatattac
    11041 tacataagag gaactttcac tagagacaat ttagatttct cagaagatgt gcttcatttt
    11101 gctgatgagg gatttgaatt aacatctgta gagcctgttg tggatgatga aagcaaccca
    11161 tttgcactta gagaagaaga tttagagaca gtatttaatg aatatgaaaa attagcagtt
    11221 aaatactctg atagattatt aaatggagac aagttcaaat tcttccactt tatgatagat
    11281 ttaaatcaag gaccttgtgt aataaagaga ataactggat gtggagcagg taatgaatat
    11341 ttagctataa ctcctgaggg agatatgtat ccatgtcatc agtttgttgg aaaagaagag
    11401 tttaaattag ctaatataaa tgatgaagaa atagtaatac ctagagaatt aacagataaa
    11461 ttcaaaaacg ctcatgtgta cagtaaggaa gattgtaaga agtgttggaa taaattctac
    11521 tgttcaggag gatgtcatgc aaatgctatg aactttaatg gcgatgtgat gaaaccttat
    11581 gaattaggtt gtgaaatgca aaagaaacgt acagaatgtt caataatgat acaagcaaga
    11641 ttaatgatag aagggaaata gtttaaatga ttaaggggta taaaggaaat aatcctgtaa
    11701 tcgatagtag cgtttttata gctgaatcag cagatataat aggaaatgtt actataggaa
    11761 aaaattctaa tgtatggtat aacgtagtta taagaggtga cgagaataat atagttatag
    11821 gtgaaaatac taatatacag gatggaactg ttatacatat agagtataat aaagatactg
    11881 taataggaaa taacgtaact gttggtcata aagctcttat acacggatgt acaataggag
    11941 ataacacttt aataggaatg ggatctataa tactaggtgg tgttgaaatt ggagaataca
    12001 ctttagtagc tgctggaagt ctgattccac ctaacaagaa aataccatct ggagtgcttg
    12061 taaaaggagc tccagcacaa gttgtaagag aacttacaga agaagaaaaa caaaatcttg
    12121 ttaattctgc attaaaatat gtagaaactg caaataatta taagtagaga tgaaaaaagg
    12181 ggcaatataa taatattgtc ctttcttctc ttataaaata aaactactta aactgagact
    12241 agggtgtgaa aaatgaaggt aagttataga catttaaaaa gatataaaga aatagttcat
    12301 atacttttaa aatatggatt cagtattatt gttgaaaaac ttaatataga aggagtagct
    12361 tataaaattc ctataacaaa tccaccggca gagataaaga atatgactac aggtgaaagg
    12421 cttagaaaag catttgaaga attagggcct acgtatgtaa aattaggaca gatattaagc
    12481 acgagaaaag atttactaga tcaaagcatt ataagtgaat tggtaaagct aagagataat
    12541 gttgaagtgt ttgatactga aattgctatg agcatattaa aagaagagct tagtatgcct
    12601 atagataaaa ttttcgaaga gtttaatgag acacctatag cagccgcatc tctagggcaa
    12661 gtttatgaag caaaattaat tagtggagaa aatgtaatag taaaaatcca aagacctaat
    12721 gttgagcagt tgataaaatc ggatgtagaa attttaaagt ctattgcatc tgctttaacg
    12781 gatataaaaa aagatttgaa tatagatgta caaggtatag ttgaagattt tgaaactcag
    12841 attttaagag agttagacta caacttcgaa gctataaatg ctgttaagtt ccaaaatatg
    12901 ttttctaata caaatgaagt ttatatacct aaagtattta tggattatac tactcaaaag
    12961 gtattagtat tggaaaaaat agttggagtt aagcttagtg acgtaaataa aatgaaaaag
    13021 ctaggctggg atacggagaa aataagtgaa ataggaatta gatctttatt taaacaaatt
    13081 tttgaatatg gatttttcca cgcagatcca catccaggaa atatatttgt tataaatgaa
    13141 aattgtatag cgtatataga ttttggaatg attggaatta ttgataagaa aatgttaaac
    13201 acattaaatt caataacact tgcagctgtg gatagaaata tagatagaat aatatactta
    13261 ctgatggagt tagatgtaat atcttatgat actaacttaa ctggtctaag acaagattta
    13321 ctttatttaa tgcattatta ctatgatgtt ccgatagata aattaagctt gggagatata
    13381 ttaaatgaag tatttagatt ttgtagaaca tataaggctg cgcttccgcc acaattagta
    13441 ttattaggaa aagctcttat taccttagag ggtacagcta gagaattaaa tcctaatttt
    13501 tcaataactg ttgcaggaaa atcatttatg aagtattact acctaaacag gttaaatcct
    13561 gaaaatttaa taaaagaatc aaaacaaagc gctcaagaag ctattgcaga tataaggata
    13621 attcctagac aagtaaaatc tattttaaga aatatagaaa aaaacaatat taaaattcac
    13681 attgaagatg ttaaattctc taaattagaa aaaataataa cagatttggc aactcaacta
    13741 tcattaagtt tagtgctagc tgcattatta gttggatcct ctttaataat agcttcgcca
    13801 aatgtaaata gcaattggtg ggtcaaagta cttgcatttt cagggtttgt agtttctttt
    13861 ttagtaggaa tacttttagt tgtgaagata ataagatcac aatatataaa aaaatagggg
    13921 gagatataca tgtttaacaa aaaatggaca cttaagtaca aaggtagcat aaaagaatat
    13981 gatttaggta aaaaaatgaa gatttccccg gaaatagggc aaattttaaa aaatagaggt
    14041 attaaagata aagaagatgc tgaaattttt ataaatccgt cattagatta cttaagagac
    14101 ccatttttaa tgaaagatat gaaaaaagct gtagatagaa taaaagatgc tatggaaaat
    14161 aagcaaaata tatgggtata tggagattac gacgttgatg gagtatcatc tacatctata
    14221 ttatgtatat atttcgactc tataggatac ccagttaaat actatatacc aaatagatta
    14281 gaggaaggat acggtataaa tgaagatgca ataagagtat tgaaggaaca agagtgtgat
    14341 ttaataataa gtgtagattg tggaataaca tctgtaaaag aagttgaatt ggcgaatgag
    14401 ttgggtatag atattataat aacagatcac catgaggtac aagataaaat accagatgcg
    14461 tatgcagtta taaaccctaa gcaaagagat tgtaattatc catttgacat gttatgtggg
    14521 tgtggagtgg cattcaaaat tatacaagca ttaacgcctg aagatgagtt taaaacttct
    14581 atgtacaagt acttagaaat agtaacttta gcgactatct gtgatatagt acctttagta
    14641 gatgaaaata gaataattgt aaaaaatggc ttaaggctta tgaaagatgg agaaaatata
    14701 ggtctaagag aacttataaa tgtttgtgga attgaaactg ataaaatagg gtcatcgcat
    14761 ataggatttt ctataggacc tagaattaat gcttctggta gactagggta ttcatattta
    14821 ggtgttgaat tatttacaac taaatcaaaa gaagaagcta tggaaatagc tagtctctta
    14881 gaagaaaaga ataatgaaag acaaatgata gaagctaaaa tgtatcaaga agcagaaaat
    14941 ataattttaa atgacaaaaa ctataattca gataaagtac tagtaatagc aaaagaagga
    15001 tggcaacatg gagttatagg tatagttgca tctaaattga cagaaaagta ttataagcca
    15061 acaatacttt taactattga agatggagaa gctactgggt ctgctagatc tataaaaggg
    15121 ttcagtatat ttgatacttt agttaattgt tcagagttac taaataaatt tggtggacat
    15181 gaacaagcag caggactatc aatggattct aaaaatatag aaactttaag aagaaaagtt
    15241 aatgaaattg caaactatca acttacagaa gatgatatgg tagaaaatat atctgtagag
    15301 tttgaattaa atgaagggtc tatagatttt aatttaatag aagaacttca tagtttagag
    15361 ccttttggaa tgagtaatcc aagtcctaga tttataatga gggaattgga aataagaggt
    15421 atttttagac taggaaaaga taaaaatcac ttaaaattaa acttagaaaa aaataacgta
    15481 tatgaatgta taggatttaa catggcatat atgtctgagc aatttgaggt aggggataaa
    15541 gttgatgtat tattccaatt agatgaaaat aactacatgg gaaatagaaa aatacaattt
    15601 ttactaaaag atataagaat ggcatatcca aaggatattg gtaaaagttt agatagtata
    15661 aatctattta gaaatattaa accttgttta gattcaaata ataaaatttc aaattatgga
    15721 aaagttaata tagatggatg caaagctata aatgtatttg actatataaa tgaaaaaagt
    15781 ttagtaattg caaattcagt aaatggattt tttaaagcat tatcagatat atcacttact
    15841 gaatatgaat ttgacataaa ttacaatatt atagagaata taaataacaa agttcaactt
    15901 atattctttc cctatattga taaaatagat ttaaaaagat ataataatat tattctttat
    15961 gattatttat atgatattga ggaatattca tgtctatttg aagaaagtga taatgaatgt
    16021 gaaattataa aatattatga taagaatgat ttaatatata taaataatat tattagaagt
    16081 ataattccag agagagaaga atttataact ttatataaaa taatgtctaa atataaagaa
    16141 ataaaaatta atatactaga cattaaatct aagttaaaca tagcaccaat aaaattattt
    16201 gctatgttaa atgtgcttaa agaattagat ttaattaatt ttcatgtgga agatgaaaat
    16261 agtactttaa caatggaaat tatgccaaaa ccaagtacta agattgattt agcttcaagt
    16321 aaagtactac aaggacttaa tcaacttaag gataaataca agcaaagcta ttaggaggat
    16381 ttaaatgaac ttaaaagatt caataagaga gattaaagat ttcccaaaac caggtatagg
    16441 attcaaagac ataacaactt tattaagcaa cggagaagca tttaagtttg cggtagatga
    16501 aataatagca gatctaaaag ataagaatgt tgatataata gttgggccag aagctagagg
    16561 tttcttaatg ggaacaccag ttgcttatgg aatgggtata ggatttgtac cagtaagaaa
    16621 gccaggtaag ttaccaggag aaactgaaaa gtttgaatat ggattagaat acggaacaga
    16681 cactttagaa atccataaag attcaataaa accagggcaa agagttgcaa tagtagatga
    16741 cttattagct acaggtggaa ctatggaagc tgcagctaaa cttatagaaa aattaggtgg
    16801 agaagttgtt tctatgcaat ttttaataga attagaagag ttaaatggta gagataaagt
    16861 atctcaatat catgtaaact cacttgtaaa atattaatag tgttcaatag ttggtaaaaa
    16921 gccaactatt ttcatatata tcaaaattta tactataaaa taggtggtac tatgcaagat
    16981 aagcaattac aagaactaat agaaaaaata aaaagatatg cccctaatgg cgatttagac
    17041 ttaattgaga aagcctatta ctatggtaaa aaagctcatg aaggacaatt aagaaaatct
    17101 ggggaaccat attttataca tccaatagct gttgctaata tactttgtga tatggaatta
    17161 gatatgcaaa ctatagcagc gggattatta catgatgtag ttgaagatac cgaatttaca
    17221 tatgaagata ttaaaaatga ttttggggaa gaaatcgcag accttgttga tggagtaact
    17281 aaacttggac agataaagta taagtctaag gaagagacgc aagctgaaaa tttaagaaaa
    17341 atgtttttag ctatgtcaaa agatataaga gtaatactta taaaattagc cgataggtta
    17401 cataatatga ggactctaaa gttcatgccg cctgaaaaag ctaaagctaa agcgacagaa
    17461 acgctagaaa tatacggtgg aattgcaagt agattaggaa tatacaaagt aaaatgggaa
    17521 ctagaagata tagcacttag atatatagat agtgatggat attatgattt ggtggaaaaa
    17581 gtagctaaga aaagaagcca aagagaagct tatatagaaa gaatagtaca tgttcttaaa
    17641 gaaaaatttg atgaagttaa tataaattgt gatatatatg gaagacctaa gcatttctac
    17701 agtatatata gaaaaatgaa aaacaagcat aaagattttg aagaaatata tgatttaatg
    17761 gcagttagaa taatcgtaaa ttcagtaaaa gattgttatg cagttttagg tatggtacat
    17821 accctatgga agccaatacc aggaagattt aaagactata tagctatgcc aaagcctaat
    17881 atgtaccaat ccttacacac tatagttgta ggaccagatg gagagccttt agaaattcaa
    17941 ataagaacta aagaaatgca taatatagca gagtacggaa ttgctgcaca ctggaagtat
    18001 aaagaaggaa aaaccagtgt taaagaaagt aaactagaag aaaaactaca atggttaaga
    18061 cagatgatgg agtgggaaaa agacttaaaa gacccacaag agtttatgga tgcattaaaa
    18121 gatgatgtgt ttaatagcca ggtatatgta tttacaccga aaggggacgt aatagaattg
    18181 ccggctggat caacgccgat tgactttgca tacagggttc ataccaatgt aggaaacaaa
    18241 tgcgtaggag ccaagataaa tggaagaata gttacattag actataaact acaaaatggt
    18301 aatattgttg agattttaac ttccgcaaat tcaagcggac caagtagaga ttggataaat
    18361 atagtacaaa ctcctaatgc taagtctaaa ataagacaat ggtttaaaaa agaaagacga
    18421 gaagaaaata tagaaagagg taacttgatt ttagagaaag aatttaaaaa atatagtata
    18481 ccaacaaaag atccaataat tgaaaaatat atgcttcaaa tggcaagaaa gtttaaccag
    18541 ccgactgtag gtgatttagt agcaactata ggatatggag gaataatgcc atctcagata
    18601 gttcctaaag taaaagagct ttatgaaaaa gatcacgtaa agaaatcttc tgagataaag
    18661 gtcatagatg atataaataa acatagtata ggtgaacaag aatatactaa gaaaagaaaa
    18721 aaatcatcgc ctcaagggat tatagtaaaa ggagtagaca atatattggt tagatttgct
    18781 aagtgctgca atccaatacc tggagatgaa attataggat atataacaaa gggaagagga
    18841 gttgctgtac atagaaaaga ttgtcctaac tctaacttag ataatgaata ctttagaaat
    18901 agattagtag aagtttcttg ggaaaactct aataatgcaa aatttgaagc tgaaattcaa
    18961 atacaagcag aagacagacg tggaattata aatgacataa cacatattgt gtctatagaa
    19021 aaagtatcat taaatggaat taatgcaaga aaaggaaagt taaatattgt aagcgtgaac
    19081 ttacttgtag aagtggacag tatagaaacg ttaactcttt taatgaaaaa agtaagagca
    19141 ataccgggag tggaagatat ttatagagtt ataaattaag gaggcattat gagagctgta
    19201 gttcagaggg tagcatcatc tagtgtcact gtagatgaac aaaaaatttc aaatattgaa
    19261 aaagggttat tagtactttt aggagtgaca catgaagaca ctagtaagga tgttgattat
    19321 ttaatagaaa aaatagttaa cttaagaata tttgaagatg aagatgaaaa aatgaattta
    19381 tctcttaaag atataaatgg agaattgatt gttgtctcgc agtttacgtt atacggagac
    19441 tgcaaaaaag gtagaaggcc taactttaca ggagcggcta agccagattt agctaataat
    19501 ttatacgaag aatttataga aaaagctaaa aaacaaaata taaatgttgg tactggaaaa
    19561 tttggagcac atatgatggt tgagctaata aatgatggac cagttacaat acttatagat
    19621 tctgaaaaaa atttttaagg gggatttagt tatgataata gagaaattta cagatcattt
    19681 atttggagaa aacacatact taatagcaga taaaaacact agagagggtg cagttataga
    19741 tccaggtgga gaagtagatg acttaatgag atttataaaa gataatttta tagatgttaa
    19801 atatataata cttactcatg ggcatggaga ccatattggt tgtgtaccta agttaaaaga
    19861 aactacaaat gcatgtataa tagctgatag tgaagagaaa gagctgcttt tagataaaaa
    19921 gaaaaactta agctataaaa tgcattgtgg ggcaactgaa tttgatgcag ataaatatgt
    19981 aaatgaggga gatagtataa aattaggaga attaaaactt aaatttatac atactccagg
    20041 gcacacaaaa ggttgtatgt gtataaaagt tggcaatcac atgtttacag gagatacatt
    20101 atttgctgga agtatgggaa gaactgactt atacagtgga gatgacaacc aaatgaaaaa
    20161 atcattaaat agattaaaaa aatatgaaga tgatataata gtatatccag ggcatggtcc
    20221 aaatactaca atgggaatag aaaaagcaac taatccatat ttagtataag gtatttgctt
    20281 agaataacaa taaaggagta gtttaaatgt taggtattga gttaaaagga catgactaca
    20341 aatatgaaat tgcagaatta ttcaagttat ttactactca atttaaattt ataaaagaag
    20401 atgaaaaatt tgaaaaagct ttgataaatg agtttattaa agatgaagat tatataaaga
    20461 gtacaactaa atactatgaa aataatgatt taaagctttg caaagaagaa gtttttaata
    20521 taaattcttt aaatgaagaa gagataaaaa agaaatctaa aactattata aaaagaagta
    20581 tatttaaggt tttaagtgaa ttgtacgata cttacgttcc atgggggatt ttgacaggga
    20641 taagacctgt taaaatagtc catagtttgt tagatgaagg actgagtgaa gttgaaataa
    20701 gacaaaacct taaagataat tatttaataa aagatgaaaa aatagattta gctttagata
    20761 tagcaaaaag agagcgtgta tttatatatc ccattgataa aaacaaaata tctttatatg
    20821 taagtattcc tttttgccct acaagatgtg tgtattgctc attcccttct aatcctatga
    20881 aacaatttgg acatttaaga gagaattacg taaaagctat tgtaaaggaa ataaaaggat
    20941 tagcgaaact attaaaagag actaataaag aaatcgaaac tttatatata ggtggaggta
    21001 caccaacaac attagaggct gaacaactag ataatttaat taaagctcta tttatggaac
    21061 ttgacttaac aaaaataaaa gagtttacag ttgaagctgg aagaccagat actataacta
    21121 gagaaaaatt agaagttatg aaaaagcata atgttactag aataagtata aatcctcaaa
    21181 ctatgaataa tgaaacttta gtcaaaatag gtagagatca taacgtagat gatatagtaa
    21241 gatgttttaa tatggctaga gatcttggat ttaataatat aaacatggat attatactag
    21301 gtttagtaga tgaaaatgtg gaaatggtta gaaatacttt agagagaata aaagaacttt
    21361 ctccagagag tttaactgta catacattag caataaaaag agcatctaca ctaaaagaaa
    21421 atctagataa gtatgaactt acaagatatg aagagatggt aagtatgata aatttatcta
    21481 tggagtatgc aaaatctatg gggcttaatc cttactatat gtacagacaa aaacatatgc
    21541 ttggaaacct tgaaaacata gggtatgcta aagaaggatt tgaatgtata tataatattc
    21601 aaattatgga agaaaagcaa agtaatcttg ctgtaggggc aggtgctatc agcaaatatg
    21661 t
//
