LOCUS       NZ_CABIWO010000001     20888 bp    DNA     linear   CON 29-FEB-2024
DEFINITION  Paraclostridium bifermentans isolate MGYG-HGUT-00024, whole genome
            shotgun sequence.
ACCESSION   NZ_CABIWO010000001
VERSION     NZ_CABIWO010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paraclostridium bifermentans
  ORGANISM  Paraclostridium bifermentans
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Paraclostridium.
REFERENCE   1
  CONSRTM   EMBL-EBI Metagenomics Team
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2019) EMG, The European Bioinformatics Institute
            (EMBL-EBI), Wellcome Genome Campus, CB10 1SD, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/29/2024 00:21:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,602
            CDSs (total)                      :: 3,499
            Genes (coding)                    :: 3,477
            CDSs (with protein)               :: 3,477
            Genes (RNA)                       :: 103
            rRNAs                             :: 11, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 5, 2 (5S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 22
            CDSs (without protein)            :: 22
            Pseudo Genes (ambiguous residues) :: 0 of 22
            Pseudo Genes (frameshifted)       :: 2 of 22
            Pseudo Genes (incomplete)         :: 13 of 22
            Pseudo Genes (internal stop)      :: 7 of 22
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:03:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 145610
            Orig. end                         :: 166498
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CABIWO010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20888
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20888
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20888
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10888](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10888
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    1100..1116
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.69"
                     /tool="antismash"
     gene            1379..2347
                     /gene="spoIIIAA"
                     /locus_tag="FY209_RS00745"
     CDS             1379..2347
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /locus_tag="FY209_RS00745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AA"
                     /protein_id="WP_148549785.1"
                     /transl_table=11
                     /translation="MNKLSDEILNSLSPKLREKIINVQYEDLNIEEIRLRVEKPLIINS
                     NNRDYFYNNSMNKLDTKNSNSYVVKKEDIEQTFQLMCKYSIHSFIDDIKKGFITLKGGH
                     RVGIVGKVIIEDGQVKNIKHISSLNIRISREVLNCSEKVLNHIIKSSNEVNNTLIISPP
                     QCGKTTLLRDIVRNLSNGNKEKGFNGIKVALIDERNEISGSYLGIAQMDVGIRTDIIET
                     CPKDIGIMMLLRAMSPNLIVTDEIGSEKEIKALYTALNGGVSLITTVHGNSIEDIRERK
                     ELSKLLDKELFKKVIILSAKNGPGTIEKIYDLEEKRWYFAN"
     gene            2337..2858
                     /locus_tag="FY209_RS00750"
     CDS             2337..2858
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /locus_tag="FY209_RS00750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AB"
                     /protein_id="WP_038285362.1"
                     /transl_table=11
                     /translation="MQIKIALISILVACSYLIGEYLYKAYTKRHKQLNELIRILEVMRM
                     DLSFGLYTLEEIFYRIGENKEFSLGPFFKHMSIDLKEDNSKTLETILSKNADFMIKESY
                     FQDKEVDELKKLILTLGKGDVYSQERMIDLSIENLKKLTTESKEDVEKKGIVYRKLSTI
                     IGLVIGILLI"
     gene            2869..3066
                     /gene="spoIIIAC"
                     /locus_tag="FY209_RS00755"
     CDS             2869..3066
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /locus_tag="FY209_RS00755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AC"
                     /protein_id="WP_021122904.1"
                     /transl_table=11
                     /translation="MDITLIFKVAGIGLLISVLNMVLEKTDRKDWTTLTTLAGVIIVLT
                     MVITEINDLFNAVRTMFQLY"
     gene            3088..3465
                     /gene="spoIIIAD"
                     /locus_tag="FY209_RS00760"
     CDS             3088..3465
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /locus_tag="FY209_RS00760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AD"
                     /protein_id="WP_224170712.1"
                     /transl_table=11
                     /translation="MKLVGLALISTILCLIIKKDRPEMAMFIGILTGIMILLSVTYKFN
                     FIIESINELANKANIPTMYISLIIKLIGIAYLMEFAIQICKDCGEGNIAAKLEFGGKII
                     VMTMSFPILISIVDMILNLIP"
     gene            3480..4652
                     /gene="spoIIIAE"
                     /locus_tag="FY209_RS00765"
     CDS             3480..4652
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589773.1"
                     /locus_tag="FY209_RS00765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AE"
                     /protein_id="WP_148549786.1"
                     /transl_table=11
                     /translation="MKKIVTSIILCILMGLTFANVSFAQEENDKKVKESVDTYISEQLN
                     KINVQEIQNQIKDEKFIEDVDLKTFMKDLISGKKTMLDLFDKEGIKLFLFDELRASLKV
                     ASIIFVLALLSSILKSLDNSFSSGAISQVTTYIVFIVMVTLTLVGFKDVLNICNTTIDS
                     MINLMQILMPILITFLVVMGFPMTSTVMTPIFMGGVTFINIVFKNFLFVSITIGFAILV
                     INNLSNSIKLKKLASFIKQINLITIGAIFTIYLALVSMQGMYVKSLDGFAVKSTKFAIG
                     NFIPVVGGFVSDSFDIILSSSQLIKNLFGGVGLIILVGICLIPIIKIISIILVYKTSAM
                     IVEPVGEDSISNFLNEISNLMAIMLACIIAITIMFFVTIAIVVSISVVAQ"
     gene            4665..5234
                     /locus_tag="FY209_RS00770"
     CDS             4665..5234
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /locus_tag="FY209_RS00770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_021433823.1"
                     /transl_table=11
                     /translation="MLESIKAWIISILIAAFIVNIVNMILPSSKLKSYINLVLNFIFIF
                     IAINPVINFFSDGTSLEDKLLKTYTKYNQQYVDSMNSLAKDTGGKSIKSGYEDGLKSIL
                     ELKLDEYGYELEDIELDGSDVSKVKVKEKNSNKEEKKDIQSSEGEKDKQVFKESSNNED
                     KKSKDEVKKSLVDILDISIENIEIDK"
     gene            5250..5798
                     /locus_tag="FY209_RS00775"
     CDS             5250..5798
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /locus_tag="FY209_RS00775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_021430047.1"
                     /transl_table=11
                     /translation="MFKNLKEDDKKKIYTLAALSFVCIMGLAIFTKNPVDKKDKETFEE
                     NKDQKSAQVEVKKDNDLESQLKNILSQIEGAGEVDVMITFSSGEQIEPAFNSNATKEET
                     TEKDAQGGERTVTTSSENKTMITSGESKPVVIKTSEPEIKGVIVVSSGASDPTVKQSLY
                     SAVQTSLQVSGHQVEIYSK"
     gene            5877..6521
                     /locus_tag="FY209_RS00780"
     CDS             5877..6521
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419166.1"
                     /locus_tag="FY209_RS00780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIIIAH-like family protein"
                     /protein_id="WP_021433822.1"
                     /transl_table=11
                     /translation="MKFNKSMFKSRGFVVMSLTLMLVVVGTVNYNLSKKSVLEASKEME
                     MYEDAQLSKNDDKKDSKKDIKVVDSKDTVVNEKAKETSKEIEKKMTSDKNMKKASYAVD
                     MKMNREKQRNELTEDLNEIINNPSTSEETRKQASNMKLQLVKDQELEIKIEDLLGAKGF
                     EDSLVYISEETVNVVVNKELQQKDAAKIFDLVANESKVNYDNIKLMSSNSK"
     gene            6678..7025
                     /locus_tag="FY209_RS00785"
     CDS             6678..7025
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /locus_tag="FY209_RS00785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_021430087.1"
                     /transl_table=11
                     /translation="MENNNFGQVKISNDVIATIAGLAAIEVEGVGTTSTFTDKLLKNNG
                     VKIQIEEDEVILDVMIIIDYGISIPDIAFKVQENVKNTVETMTGLKVSQVNIHVQGINF
                     KKEKVEKAEAK"
     gene            7119..7625
                     /gene="nusB"
                     /locus_tag="FY209_RS00790"
     CDS             7119..7625
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589768.1"
                     /locus_tag="FY209_RS00790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_148549787.1"
                     /transl_table=11
                     /translation="MRKAKMITTREYMMKFIYQIDMNKEDLTDLNDKLENFLNDNFEYI
                     KNRYEELKLQFSDEADVELEETELSQFIDLKYSKELVESFNANKESIDSLINKYAKNWT
                     INRMAKVDLAILRLAICEILYMSEMPTKVSINEAIELAKLYCDDKSPKFINGILGSVVS
                     EIGEK"
     gene            7606..8571
                     /locus_tag="FY209_RS00795"
     CDS             7606..8571
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287348.1"
                     /locus_tag="FY209_RS00795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="WP_226888228.1"
                     /transl_table=11
                     /translation="MKSEKNKNIIIGLDTSCYTTSIAAISLEKSIVFNKKIMLKVKKDS
                     KGLRQSEMVFQHVNNLGEISEELKNIMNGYNICAICASEKPRPINDSYMPAFTVGYNFA
                     KLFSSMNNINLYSTTHQENHIEASLYEKKLRSNKFISVHMSGGTTEILLVEKHNDVSNI
                     RIIGGSKDISFGQLIDRLGVQLGYEFPCGKYIDKNALECNQNIDVGIKTSVKDGYMNLS
                     GIENQITKLKNDFDEKYISKSLMDSIVRSLYKALRFLCKEYDISEVVFAGGVASSKYIK
                     DGLSQKLYKDKVISFFAKPEYSTDNALGCALIGLNKFIGE"
     gene            8574..9770
                     /gene="xseA"
                     /locus_tag="FY209_RS00800"
     CDS             8574..9770
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /locus_tag="FY209_RS00800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_148549788.1"
                     /transl_table=11
                     /translation="MKLRALDVSEVNSYVKRILTNDAVLYNLKVKGEISNFKVHSSKNV
                     YLTLKDKSSKINCVIFKNNYDSSLNLEDGMKVIATGYISVYERDGSYQLYIENVELDGL
                     GNLYIEFLKLKEKLEKEGLFDYIHKKPIPKMPKNIGIITSETGAVIKDIINVVKRRYPK
                     VNIKLYSVSVQGKNSSEQICEGIKFFNNANNVDTIILGRGGGSIEELWSFNEESVAREI
                     FSSHIPIISAVGHETDFTIADFVADMRAPTPSAAAEIATPKLDDLLYKLKNSKDRLDKA
                     LINQSKLDKNKLNNVYDRLNTIVKSYIIRDKIIQIDIIYDKITNEINDVVKLKKGSLDS
                     SGSLLHSLSPLATLDRGYSIVQKDKTTINTINSLKEKDSIAIKFKDGTADCIIEKIKD"
     gene            9783..9998
                     /gene="xseB"
                     /locus_tag="FY209_RS00805"
     CDS             9783..9998
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /locus_tag="FY209_RS00805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_021429988.1"
                     /transl_table=11
                     /translation="MNLSYEEAYQRLEEILNKLESGTTSLDDSLNLYEEGIRLYSHCNK
                     LLDEANLKIDKFSKDGKEVPFSIEEE"
     gene            10001..10888
                     /locus_tag="FY209_RS00810"
     CDS             10001..10888
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /locus_tag="FY209_RS00810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_148549789.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.2e-59, bitscore:
                     197.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFKEELKNRVVNIEDLLNEYMPKVEGYQKTIFDSMNYSLKAGGK
                     RLRPILTLEACKLVGGNEKDAYPFAVAIEMIHTYSLIHDDLPALDNDDLRRGRKTNHKV
                     YGEAMAILAGDGLLNYAYEIMLRESLSKGEPEKYLKAINEIAKASGIYGMIGGQVVDIE
                     SEGKSIDMEKLDFIHMNKTAAIIIGCMRAGAIIGGASEEELANVTKYAKNIGLSFQIVD
                     DILDIVGDEAKLGKKVGSDIDNEKSTYPSLIGLEKSKETANKLIAEAKMSIDYINKDSE
                     FLNNLADYIVDREY"
     gene            10898..11335
                     /locus_tag="FY209_RS00815"
     CDS             10898..11335
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844841.1"
                     /locus_tag="FY209_RS00815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="divergent PAP2 family protein"
                     /protein_id="WP_148549790.1"
                     /transl_table=11
                     /translation="MSFISGIFSNKVLLISMFACFLAQLFKIFTGDQKKIQISRIFTSG
                     GMPSSHSSFVTSLSTLVGMEYGFNSTEFAVVAVFSMIIMYDASGVRRAVGKQAVILNQI
                     VDDLQHKKHIEQKKLKELVGHTPVEVFFGAILGIITALVFS"
     gene            11379..13241
                     /gene="dxs"
                     /locus_tag="FY209_RS00820"
     CDS             11379..13241
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843742.1"
                     /locus_tag="FY209_RS00820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_148549791.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 2.6e-122,
                     bitscore: 404.3, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-06, bitscore:
                     25.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYNYLNNVNSPKDIKKMSTKELDLLAKDIRKFLVRSVSKTGGHLA
                     SNLGVVELTLALHKVFDSPKDKFIWDVGHQAYVHKILTGRKDQFDTLRQFNGLSGFPKE
                     CESEHDIFDTGHSSTSISVGSGIACARDIKGEDFSVVSIIGDGSITGGMALEALNHIGY
                     INTNMIVILNDNEMSIDENVGGMSKHLSAIIKNSTVNKVKDEVEKILNVTPGGNILSKT
                     ASKVKDSIKGNFTLQECAFFDSLGITYLGPIDGHDIDEIVKTLEKAKQQNGPILLHVIT
                     KKGKGYKFAEDEPHKYHGVSKFDIKTGLKPSSSKSISSVVGEKLIDLATKDENVVAITA
                     AMPSGTGLNKFSEIYPNRYYDVGIAEQHAVTFSSGLAKAGMKPYFAVYSSFLQRAYDQI
                     IHDIAITIKNVTLLIDRAGLVGNDGETHHGIFDLSYLNNIPNMTVMAPKDTKELELMMD
                     LSLEIEGPMAIRYPRGSSYFVDKGEYKPIKVGTYELLSEGKDIAILAIGNMVKQSIEAV
                     DILNKSGINPTLVSARFLKPIDEKLIMDLAKNHKYIVTVEDNVLTGGFGSRINKFIIDN
                     KLDNEIINIGIKDEFIPHGDVNVLYEQCGISPSGIAQQIESLLR"
     gene            13255..14064
                     /locus_tag="FY209_RS00825"
     CDS             13255..14064
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /locus_tag="FY209_RS00825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_021433814.1"
                     /transl_table=11
                     /translation="MKKRIDVLLVEQGYFDSRERAKKAIMAGLVFVDNQRCDKAGSEVK
                     EESKIEVKGNPIPYVSRGGLKLEKAMKNFDITLENKVCLDIGASTGGFTDCMLQNGAKK
                     VFSIDVGYGQLAWKLRQDERVVCMERTNIRHVTIEDTKEFGQFASIDVSFISLKLVLPK
                     AKELLDPSGQVVALIKPQFEAGREKVGKKGVVREKSTHIEVIEKVADFAAEIGFTILGL
                     DYSPIKGPEGNIEYLIHLKNSNEGYEYNKEEFKITIDKVVDNSHNLM"
     gene            14083..15768
                     /gene="recN"
                     /locus_tag="FY209_RS00830"
     CDS             14083..15768
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /locus_tag="FY209_RS00830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA repair protein RecN"
                     /protein_id="WP_148549792.1"
                     /transl_table=11
                     /translation="MILELYMKNCALIEELRLDIDKNLNILTGETGSGKSIIIGALGLC
                     LGGKYDRSFLRKGTEKGLVEALFDVNNQKLKEKLLENGIDIEEDNQIIISKEIFDDGKS
                     ISRINGRNVKVSFLKEISNYLIDIHGQHQNQVLFDKDTHIDFLDLFGEELLYESKSDYE
                     KTYIEYNEVKKALNVLTENKDDMQIQREIDLIKFQINEIELANLNENEYEDLLKQRDVY
                     RNGEKIFTNLNNAYLNLYDGSINSVDLISKSLGDLGAIAQYDEKLNDYNDTIERIMYEL
                     QDISRDIRSYKENIDFSPYELEQIEQRVDEINTLRRKYGDTIEEILAYKDKINERLDEI
                     LNRDEKVEELKLKLKKVEDILVIKAEKLTQKRKEVARNLQEKLLYELKSLNMKNVVFEV
                     SFGKSTFNAKGQDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILADIDEIDTL
                     VFDEIDTGISGIAAQIVGEKLSLIAKKKQIICITHLPQIAANADTHYCIEKKTSNERTF
                     TVISRLDDNQRKDEIARLIAGSNITEKTMEHASEIIELAKKVPN"
     misc_feature    15772..15785
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: weak, score: 15.81"
                     /tool="antismash"
     gene            15871..16854
                     /locus_tag="FY209_RS00835"
     CDS             15871..16854
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017400.4"
                     /locus_tag="FY209_RS00835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIVB peptidase S55 domain-containing protein"
                     /protein_id="WP_187359352.1"
                     /transl_table=11
                     /translation="MKKIYIVLSLVLIIPIFILGISKPENKKETRYLVPLGNVVGIRAN
                     TDGILVLENEDSSVDYIDGVEAGDNIISINGINVYSSKDVKRVLHNYNKDLVEIIIDRD
                     GELISKQIPVKKENNEYKLGIWIRDKISGIGTMTFYNPQNNTFSALGHPIKDIDTNELI
                     KVKSGNIYNAEDISIEKGRVKHVGQIKAEFDGDKPIGNFKKNNSFGISGNLTTYDNEGK
                     EKMLEVGDSKDIKLGPAIILFQNKDGKIGQYQINIKKIKYNNKKDDKDMVIEVVDERLI
                     NYTGGIVQGMSGAPIIQNDKIIGAVTHVFIDNSKIGYGIFIDKMII"
     gene            16975..17793
                     /gene="spo0A"
                     /locus_tag="FY209_RS00840"
     CDS             16975..17793
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589758.1"
                     /locus_tag="FY209_RS00840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_021429605.1"
                     /transl_table=11
                     /translation="MSEKIKIVLADDNRDFCQVLREYLSNEDDIEILGIAKDGIEALDL
                     VSRTQPDVLVLDVIMPHLDGLGVIEKLNAMNLPKMPKIIVLSAVGQDKITQSAINLGAD
                     YYIVKPFDFVIFINRIRGLVSNKNTVVDSNSRSNNNMDIKMTKTDFVKNVGNIETEITN
                     IIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRVERAIRH
                     AIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            17890..19092
                     /locus_tag="FY209_RS00845"
     CDS             17890..19092
                     /EC_number="2.7.7.72"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF009814.0"
                     /locus_tag="FY209_RS00845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="WP_226888229.1"
                     /transl_table=11
                     /translation="MKINIPTDVKEIIDDIYENGYEAYIVGGCVRDSIVGIKPNDYDIT
                     TNAKPTDTISIFKNYKIIETGIKHGTITLIKNKNEYEITTYRIDGTYADNRRPEYVEFT
                     RDIIEDLKRRDFTINSIAYNHKVGIVDAFEGIEDINKKIIRTVGNPDERFKEDGLRIIR
                     AVRFSSKLNFKIDSKTLESIYKNIKLIKNISSERIQEELNKILLSNYPEKIYILYDAKM
                     FDIFEMENVKMNKNDLAKLKSSKKDLVIRLSIFIYILGDINESKKILELLRYSNKIKSQ
                     CITILDKLDNKIIDDKVSIKIYLKEIGHESLNYLLYVKKILDIEFEKKYYDKINNLIKE
                     IDLNKECYSLKELALNGRDLNALGYKGKEIGEKLNFLLYNVIENPNINNKTDLINIINS
                     L"
     gene            19183..20304
                     /gene="steA"
                     /locus_tag="FY209_RS00850"
     CDS             19183..20304
                     /codon_start=1
                     /gene="steA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /locus_tag="FY209_RS00850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative cytokinetic ring protein SteA"
                     /protein_id="WP_148549795.1"
                     /transl_table=11
                     /translation="MRVEAPIKVDRKTKRLAKRLTGGEIAVINHKDVDEVAANSLVEGK
                     IKLVINASQSISGRYPNKGPGILVDKNILIVDNVGEELFNNLQEGQIIEVIDGKIYRDG
                     ELLGQGEVLDKDEVDNKIRLAYENLAVELDRFIDNTIDYAKKEKGLILGEVEIPKVSTD
                     YKNRHVLIVVRGQDYKQDLSTILSYIEEMKPILVGVDGGADALIEFGYTPDVIVGDMDS
                     VSDEALQKAKEIVVHAYTDGRAPGLKRVQDLGLESVVFPAPGTSEDIAMLTAYEYKAEL
                     IVAVGTHSNMIDFLEKGRPGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKLKYIWALIA
                     TALFPVLILASFSPSVQQFMHLMELKMRLLLQM"
ORIGIN
        1 gtaaaaaact ttaatccaga agattatata aataaaaaag aattaaaaag aatggataga
       61 tttactcatt ttgccatagc atcttcgcaa atggcagtaa aagatgcaaa tcttgactta
      121 gataaagtag atagtgaaaa aatgggagtt ataataggtt ctggtatagg aggagttgct
      181 acgatagaag agcaacacaa aattttacta gaaaaaggaa atagaagagt tagcccattt
      241 ttcgttccta tgatgatttc taacatggcg gcaggccaag tatctattgc attaggtgca
      301 aaaggaccaa acactaatgt atctactgct tgtgcatcag gatctcatgc tataggagat
      361 gcatttaaag ctatacaaag aggcgatgca gatataatgg tagcaggagg aagtgaagct
      421 ggtgttacac cactttcatt tgcaggtttc tgtaatatga aggctatgtc tactagaaat
      481 gatgacccaa aaactgcttc aagaccattt gataaagata gagatggatt tgtaatggga
      541 gaagggtcag gtatattaat actagaagat ttagatcatg ctataaaaag aggtgctaag
      601 atttatgctg aaatagttgg atatggtgca acagcagatg cataccatat gacaactcca
      661 gcagaaaatg gagaaggcgc agctagatct ataagtatgg cgatgaaaga tggaaacatc
      721 cctattggtg aagttgatta tataaatgct catggaacat ctacttacta taatgataag
      781 tttgaaacaa tggcaatcaa aaatgttttt aaagaccaag catatgaact ttgcgtatca
      841 tctacaaagt ctatgacagg ccatttatta ggagctgcag gagcagttga agctattgta
      901 tgcgctatgg ctataagtga cggatatgtt cctcctacta taaatgtaga aaacttagat
      961 gaagatctag atttagatta cgttgtaaac gaaggtaaga aaagagatgt tagatatgca
     1021 ttatcaaatt ctttaggatt tggtggacac aatgcaactt tagcatttaa aaaatatgaa
     1081 taaataatta ttaaaagagt tgcctaaaac aggcaactct ttttttacgt ttaagtagat
     1141 tatgattact aaaaatatgt ggataatcta tgaaacttag ttgtattaat attatatttt
     1201 ttgagcgtaa aaaagatttt tgagcaacgg acgaagtcgt ttgagtaacg ggacacgagt
     1261 tgcgagtgga cgttgacgac atgaaatttg agcgatatga gcgaagtgaa tttttgtttt
     1321 ttgtcataaa tatttaacct tgaaaatata attatataaa caaaggagga caagggatat
     1381 gaataaactt tcagatgaaa ttttaaattc tctatcgcct aagctaagag aaaaaataat
     1441 aaatgtacaa tatgaagatc taaatataga agaaataaga cttagagtag agaaaccatt
     1501 aataataaat tctaataata gagactattt ttataataac tctatgaaca aactagatac
     1561 aaaaaattca aattcgtatg tagtaaaaaa agaagatata gaacagacat ttcaacttat
     1621 gtgcaaatat tcaattcatt catttataga tgacattaaa aaaggtttta taacattaaa
     1681 aggtgggcat agagttggaa tagttggaaa ggtaataatt gaagatggac aagttaaaaa
     1741 tataaagcac atatcatctt taaatataag gatttctaga gaggtattaa attgctctga
     1801 aaaagtatta aatcacataa ttaagagttc taacgaagta aataatactt taataatttc
     1861 accgccacaa tgtggtaaaa caacattact tagagatata gttagaaatt taagtaatgg
     1921 gaacaaagaa aaagggttta atggaattaa agtagctctt atagatgaaa ggaatgagat
     1981 ttcaggatca tatttaggaa tagctcagat ggatgttgga ataagaacag acataataga
     2041 aacatgccca aaagatatag gcataatgat gttacttagg gctatgtcac ctaacttaat
     2101 agtaacggat gaaataggta gtgaaaagga aataaaagct ttgtacacgg ctttaaatgg
     2161 gggagttagc ttaataacta cagtacatgg gaattccata gaagatataa gggaaaggaa
     2221 ggaattaagc aaattactcg ataaagaatt attcaaaaaa gtaataatac tttcggctaa
     2281 aaatggacca gggacaattg aaaaaatata tgacttagaa gaaaagaggt ggtattttgc
     2341 aaattaaaat agctctaata agtattttag tagcatgtag ctatctgatt ggagagtatt
     2401 tatacaaagc ttatacaaaa aggcataaac agttaaatga gctcataagg atattagagg
     2461 taatgcgaat ggacttatca tttggattgt acacattgga agaaatattt tataggatag
     2521 gagaaaataa agaattttca cttggacctt tctttaaaca tatgagtata gatttaaaag
     2581 aagataatag caaaacatta gaaactatat tatcaaagaa tgctgatttt atgattaaag
     2641 aaagttattt tcaagataag gaggtagatg aattaaaaaa attaatactt actcttggaa
     2701 aaggagatgt ttattctcaa gagaggatga ttgatttatc tattgaaaat ttaaaaaaac
     2761 tcacaacaga aagtaaagaa gatgtagaga aaaaaggtat agtatacaga aaactatcta
     2821 ctataattgg gttagttata gggatacttt taatatagga gggttaatat ggatataact
     2881 ttgattttta aagttgcagg gattgggtta ttgatatctg ttttaaatat ggttcttgag
     2941 aagactgata gaaaagattg gactacctta acaactcttg caggtgtgat aattgttctt
     3001 acgatggtaa taactgagat aaatgatcta tttaatgcag ttagaacgat gtttcagtta
     3061 tattaagggg gagatctttt ggatgtaatg aaattggtag ggcttgcgct tatctctact
     3121 atattatgct taattataaa aaaagataga ccagaaatgg ctatgtttat aggaatacta
     3181 acaggaatta tgattttact ttctgtaacc tataagttca attttataat tgaaagtata
     3241 aatgaattag caaataaggc taacatacct actatgtata tatctttaat aatcaaactt
     3301 ataggaatag catacttaat ggagtttgct attcagatat gcaaagactg tggggaagga
     3361 aatattgcag ctaagcttga attcggagga aaaattatag ttatgactat gtcattccct
     3421 atattaatat ctattgttga tatgatttta aatttgattc cataggagaa tgattactta
     3481 tgaaaaaaat tgtgactagt ataattttat gtatactaat ggggctaaca tttgcaaatg
     3541 tttcatttgc acaagaagaa aatgataaaa aagtaaaaga aagtgtagat acatatataa
     3601 gtgaacaatt aaataaaatt aatgtacaag aaattcaaaa ccaaataaaa gatgaaaagt
     3661 ttatagaaga tgtagatctt aaaacattta tgaaagattt aatatctggt aagaaaacaa
     3721 tgctagattt atttgataaa gagggtatta aactattctt attcgatgaa ttgagagcaa
     3781 gtttaaaagt tgcatcaata atatttgtct tagcgctctt atcatctatt ttaaaaagtt
     3841 tagacaattc attctcatct ggggcgataa gccaagtaac aacctatatt gtatttatag
     3901 taatggtaac tttaacattg gtaggattta aagatgtttt aaatatatgt aacaccacca
     3961 ttgatagcat gatcaatttg atgcagatac taatgccaat attaataaca tttttagtgg
     4021 taatgggatt tcctatgaca tctactgtta tgacccctat atttatggga ggagtaacat
     4081 ttataaatat agtttttaaa aacttcctat ttgtatctat tacaataggt tttgcaatac
     4141 ttgttataaa taatttatct aatagtataa aacttaaaaa gttggcatct tttataaaac
     4201 aaataaatct gataacaatt ggagccatat ttactatata tttagcatta gtatctatgc
     4261 aggggatgta tgttaagagt ttagatggat ttgcagttaa aagtactaag tttgcgatag
     4321 gaaattttat acctgttgta ggaggatttg tatcagactc atttgatata atattatctt
     4381 catctcaact tataaagaac ttatttggag gggtgggact cataatatta gtcggaatat
     4441 gcttaattcc tataataaaa atcatttcaa taatattagt ttataaaaca tcagcaatga
     4501 tagtagaacc agttggagaa gatagtattt cgaacttttt aaatgagatt tcaaatctta
     4561 tggcaataat gttagcctgt atcatagcta taacaataat gttttttgtt actatagcaa
     4621 tcgtagtttc tattagtgtt gtggcacagt aaaaggagga atatatgtta gagagtatta
     4681 aagcttggat aataagtatt ttaattgcag cctttatagt taacatagtt aatatgattc
     4741 ttccttcttc aaaattaaag tcatatatta atctagtttt aaattttata tttatattca
     4801 ttgctataaa tccagtcatt aatttttttt cagatggaac aagtttagag gacaaattat
     4861 taaaaacata cactaaatat aatcaacaat atgttgatag catgaatagt ctagctaaag
     4921 acacaggggg gaaaagcata aagtctgggt atgaagatgg attaaaaagc atattagaat
     4981 taaaactaga tgaatatggt tatgaacttg aggatattga attagacgga tctgatgtaa
     5041 gtaaagttaa ggttaaagaa aaaaatagta ataaagaaga aaaaaaggac atacaatcta
     5101 gtgagggtga aaaagataaa caagtattta aagaaagctc aaataatgaa gataaaaaat
     5161 caaaagatga agttaaaaag agcttagtag acatacttga tatatccatt gaaaatatag
     5221 aaattgataa ataggggttg agaataggta tgtttaaaaa cttaaaggaa gatgataaga
     5281 aaaagatata cactctagcc gcgctgtcgt ttgtgtgtat tatgggacta gctatattta
     5341 caaaaaatcc agttgacaaa aaagataaag aaacttttga agaaaataaa gatcaaaagt
     5401 ctgcacaagt agaagtaaaa aaagataatg atttagaaag tcaacttaaa aatatattat
     5461 ctcaaataga gggagcagga gaggttgatg tgatgattac tttttcatct ggtgaacaaa
     5521 tagaaccagc atttaactca aatgctacaa aggaagagac gactgaaaaa gatgctcaag
     5581 gtggagagag aacagttact acgtcaagtg aaaataaaac aatgataact tcaggagaaa
     5641 gtaaacctgt agttataaaa acgtcagagc cagaaataaa aggggttata gtagtttcta
     5701 gtggggctag cgatccaact gtaaaacaaa gtctatactc agcagttcaa acatcacttc
     5761 aggtttcagg acaccaagtt gaaatttatt ctaaataggt aaaaaaatat tcataataaa
     5821 aaagctcgta catataaata ttacaagaat ataattatta attaggggga gtataaatga
     5881 aatttaacaa aagtatgttt aaaagtagag ggtttgtcgt aatgtcatta acacttatgt
     5941 tagtggtggt tgggacagta aattataatt taagcaaaaa atctgtatta gaagcatcta
     6001 aagaaatgga aatgtatgaa gatgctcaac tatcaaaaaa tgatgataaa aaggactcta
     6061 aaaaagatat taaagttgta gacagcaaag atactgtagt taatgaaaaa gctaaagaaa
     6121 ctagtaaaga aatagaaaag aaaatgactt ctgataaaaa tatgaaaaaa gcatcatatg
     6181 cagtagatat gaaaatgaat agagaaaaac aaagaaatga gttaacagaa gatttaaatg
     6241 aaataataaa taatccatct acatcagaag aaactagaaa gcaagcatct aatatgaaat
     6301 tacaacttgt aaaagatcaa gaattagaaa ttaaaataga agatttatta ggagcaaaag
     6361 gatttgaaga ttcattagtg tacataagtg aagaaactgt taatgtagta gtaaacaaag
     6421 aattacaaca aaaagatgca gctaaaatat tcgatttagt tgcaaatgag tcaaaagtta
     6481 actatgataa tataaaactt atgagcagta attctaaata agtataaatg cctcagttat
     6541 actggggctt ttttatgtac aataataagt cgattacata aatactagat taagcaaatc
     6601 taacttttta ttgcaaatta aagctctatt tggtattatt atataataaa atagtttata
     6661 tagggatgtg atatatgatg gaaaataata actttggaca agttaagata tcaaatgatg
     6721 tcatcgctac tatagcagga ttagcagcta ttgaagtaga aggagtagga actacatcga
     6781 cattcacaga taaattacta aagaataatg gtgttaagat acaaatagag gaagacgaag
     6841 ttatcttaga tgttatgata ataattgatt atggaatatc tatacctgat atagctttta
     6901 aagtacagga aaatgtaaaa aatacagttg aaacaatgac tggattaaaa gtttctcaag
     6961 ttaatataca tgttcaagga atcaacttta aaaaggaaaa agttgagaag gcagaagcaa
     7021 agtaatcatc tacgataaat taatatttcc ctctgaaaat cagagggttt ttttatgagt
     7081 aaatatgtat atactaaatt caaaggagga ataagcaaat gagaaaagct aaaatgataa
     7141 cgacgagaga gtatatgatg aagtttatat accaaataga catgaataaa gaggatttaa
     7201 ctgatttaaa tgataaatta gaaaacttct taaacgataa ctttgaatac ataaagaata
     7261 gatatgagga attaaaatta caattttcag atgaagcgga cgttgaatta gaagaaacag
     7321 agttaagcca atttattgat ttaaaatata gcaaagaact agttgaaagc tttaacgcaa
     7381 ataaagaaag catagattct ttaataaata aatatgctaa aaactggact ataaatagaa
     7441 tggctaaagt agacttagca atacttagac ttgctatttg tgaaatacta tacatgtcag
     7501 aaatgcctac taaagtttct ataaatgaag ctatagaatt agctaaactt tactgtgatg
     7561 acaaatctcc taagtttata aatggaatat taggaagtgt tgtaagtgaa atcggagaaa
     7621 aataaaaata taataatagg attagatact agctgctata caacttctat agcagctata
     7681 tctttagaaa aaagtatagt atttaataaa aaaattatgt taaaagtaaa gaaagattca
     7741 aaagggctaa gacaaagcga aatggtgttt caacacgtaa ataatttggg ggaaataagt
     7801 gaagaattaa aaaatataat gaacggatat aatatatgtg caatatgtgc atctgaaaaa
     7861 ccaaggccga taaatgattc atatatgcct gcatttacag taggatataa ttttgcaaaa
     7921 ttatttagta gtatgaataa tattaattta tattcaacaa ctcatcaaga aaatcatatt
     7981 gaagccagct tatatgaaaa aaaattaaga agtaataaat ttatttctgt tcatatgtcg
     8041 ggaggaacaa cagaaatatt attagttgaa aaacataatg atgtatcaaa tattagaata
     8101 ataggtggaa gtaaagatat aagttttgga caattaatag atagattagg tgttcaatta
     8161 gggtatgagt ttccatgtgg aaaatatata gataaaaatg ctttagaatg taatcaaaat
     8221 atagatgtag gaataaagac atctgtaaaa gatgggtata tgaacctatc tgggatagaa
     8281 aatcaaatca ctaagctgaa aaatgatttt gatgaaaaat acatatctaa atcactaatg
     8341 gactcgatag ttagaagttt atataaagct cttagatttt tatgtaaaga gtatgatata
     8401 agcgaagttg tatttgctgg aggggttgca tcaagcaaat atataaaaga tggtttaagt
     8461 caaaaactat ataaagataa agtaataagc ttttttgcaa aacctgaata tagcacagat
     8521 aatgcattag gttgtgcact tataggatta aataaattta taggagaata gctatgaaat
     8581 taagagcttt agatgtaagt gaagttaatt catacgtaaa aagaatctta actaatgatg
     8641 cagttttata taacttaaaa gtaaaaggtg aaatttcaaa ctttaaagtt catagcagca
     8701 aaaatgtata tctgactctg aaagataaat catctaaaat aaactgtgta attttcaaaa
     8761 ataattatga tagttcacta aatttagagg atggaatgaa ggttatagca acaggatata
     8821 tatctgtgta cgaaagagat ggatcatatc aattgtatat agaaaacgtg gaattagatg
     8881 gactggggaa tttgtatata gaatttctaa aattaaaaga aaagttagaa aaagaaggtt
     8941 tgtttgacta tatacataaa aagcctatac ctaaaatgcc taaaaatata ggtataataa
     9001 catctgagac aggagcagtt ataaaagata taattaatgt tgtaaagcgt agatatccaa
     9061 aagtaaatat aaagctttat tctgtttcag ttcaaggaaa aaactcttct gaacagatat
     9121 gtgaaggaat taaatttttt aataatgcta ataatgtaga tacaataata cttggaagag
     9181 gtgggggatc catagaggaa ttatggtctt ttaatgaaga gagcgttgca agagagatat
     9241 ttagttcgca catacctata atttcagctg taggacatga gacagacttt acaatagctg
     9301 attttgtggc tgatatgagg gcacctacac catctgcagc tgcagaaata gcaaccccaa
     9361 aattagatga tctattatac aagttaaaaa actctaaaga cagattagat aaggctctta
     9421 taaatcaatc taagctagat aaaaataaat taaataatgt ttatgataga ctaaatacta
     9481 ttgttaagtc ttatataata agagataaaa ttatacaaat cgatataata tatgataaaa
     9541 taactaatga gattaatgat gtagtaaaac ttaaaaaagg aagtttagat agtagtggat
     9601 ctcttttgca tagcttaagt ccacttgcta cattagatag agggtacagt atagtacaaa
     9661 aggataaaac tactataaat acaataaata gcctgaaaga aaaggatagt atagcaatta
     9721 aatttaaaga tggtacagct gattgtataa ttgaaaaaat taaagattaa agaggtataa
     9781 aaatgaattt atcttatgaa gaagcttatc aaagactgga agaaatttta aataaattgg
     9841 agtctggaac tacaagttta gatgactctc ttaatttata tgaagaggga ataagacttt
     9901 atagtcattg taataaatta ttagatgaag caaatttaaa aatagataag tttagcaaag
     9961 atgggaaaga ggtacccttt agtatagagg aggagtagtt atgaatttta aagaagaatt
    10021 aaaaaataga gttgtaaata tagaagattt attaaatgaa tatatgccta aagttgaagg
    10081 ataccaaaaa actatatttg actcaatgaa ttatagttta aaagctggag gaaaaagact
    10141 aagaccaata cttacattag aagcttgtaa actagttggg ggaaatgaaa aagatgcata
    10201 tccatttgct gtagctatag aaatgataca tacatattct ttgatacatg atgatcttcc
    10261 agctcttgac aatgatgatc ttagaagagg aagaaaaact aatcataaag tgtatggaga
    10321 agctatggct attttagctg gagatggact tttaaattat gcttatgaaa taatgcttag
    10381 agagtcttta agtaaaggtg agccagaaaa atatttaaaa gctataaatg aaatcgctaa
    10441 agcttctggg atatatggta tgattggtgg acaagttgtt gacattgaaa gtgaaggtaa
    10501 atcaatagat atggaaaaac ttgactttat acatatgaat aaaacagcag caataatcat
    10561 tggatgcatg agagcaggag ctataattgg tggagcaagt gaagaagagt tagcaaatgt
    10621 aactaaatat gcaaaaaaca taggattatc attccaaata gttgatgata tattagatat
    10681 tgttggagat gaggctaagc ttggtaaaaa agtaggaagt gatatagata atgaaaaatc
    10741 tacttatcca tcacttatag gacttgaaaa gtcaaaagaa actgctaata aattaatagc
    10801 agaagctaaa atgagtattg attatataaa taaagatagt gagtttttaa acaacttagc
    10861 tgattatata gtagatagag agtattaagg aggaacgatg agctttattt caggaatttt
    10921 tagcaacaaa gtgttgctta taagtatgtt tgcttgtttc ttggcacaac tttttaagat
    10981 ttttacagga gatcaaaaaa agattcaaat atctagaata tttacttctg ggggtatgcc
    11041 aagttctcat agttcttttg ttacatcctt atctacatta gtaggaatgg agtatgggtt
    11101 taattcaaca gaattcgcag tagttgcagt gttttctatg ataataatgt atgatgcatc
    11161 tggagtaaga cgtgcagttg gaaagcaagc agtaatatta aatcaaattg tagatgattt
    11221 acagcataaa aagcatattg aacaaaaaaa attaaaggaa ttagtaggac atacgccagt
    11281 agaagttttt tttggcgcta ttttaggaat tattacagca ttggtattta gttaaagtat
    11341 taatgctaaa aactacttag ataaaaggtg agaaagttat gtataattat ttaaataatg
    11401 taaattctcc taaagatata aaaaaaatga gcactaaaga gctagattta ctagctaaag
    11461 acataagaaa atttttagtg agatcagttt ctaagacagg tggacattta gcatctaatt
    11521 taggtgttgt agagcttact ttagcactac ataaggtatt tgatagtcca aaagataaat
    11581 ttatatggga tgtaggacac caggcttatg ttcacaagat acttacagga agaaaagatc
    11641 agtttgatac attaagacaa tttaatggat taagtggatt tccgaaagaa tgcgaaagtg
    11701 aacatgatat atttgataca gggcatagta gtacatctat atctgtagga agtggaattg
    11761 catgtgctag agatataaaa ggcgaagatt tttctgtagt ttctataatt ggagatggat
    11821 caataacagg cggaatggct ttagaggctc ttaaccatat aggatatata aatacgaata
    11881 tgatagtaat attaaatgac aatgaaatgt ctatagatga aaatgttgga ggaatgtcta
    11941 aacatttatc ggctattata aaaaattcaa ctgtcaataa ggttaaagat gaagttgaaa
    12001 aaatattaaa tgttactcct ggaggcaaca tactatctaa aacggcaagc aaagtaaaag
    12061 atagcataaa aggaaacttt acattacaag aatgtgcttt ttttgattct ttaggaataa
    12121 catacttagg gcctatagat ggacatgata tagatgaaat agtaaaaaca ttagaaaaag
    12181 caaaacaaca gaatggacca atattacttc atgtgataac taaaaaaggt aaaggctaca
    12241 agtttgcaga agatgagcca cataaatacc atggagtttc taaatttgat ataaaaactg
    12301 gattaaaacc atcttcatca aagagtatat cttcagtagt aggagaaaag ttaatagacc
    12361 ttgcaactaa ggatgaaaat gttgttgcta taacagctgc tatgccatca ggaacaggct
    12421 taaataagtt ttctgaaata tacccaaaca gatattatga cgttgggatt gcagaacaac
    12481 atgcagttac atttagttca ggactagcaa aagctggaat gaaaccatat tttgcagtat
    12541 actcatcttt cttacaaaga gcatatgatc aaataataca tgatattgct ataacaatta
    12601 agaatgtaac tttacttata gatagagcgg gacttgtagg taatgatgga gaaacacacc
    12661 atggaatatt tgatttaagc tatttaaata atatacctaa catgactgtg atggctccta
    12721 aagatacaaa ggaactagag ctaatgatgg atttatcttt agaaatagaa ggacctatgg
    12781 ctattagata tccaagagga agtagttact ttgtggataa gggtgagtac aagcctataa
    12841 aagttggtac atatgaacta ttaagcgaag gtaaagacat tgctatatta gcaataggta
    12901 atatggttaa acagtcaatt gaagcagtag acatattaaa taaatcaggt attaatccaa
    12961 ctttagttag tgcaaggttt ttaaagccta tagatgaaaa attgataatg gatttagcta
    13021 aaaatcataa atatattgtt actgtagaag acaatgtact tacaggtgga tttggaagta
    13081 gaataaataa atttattata gacaataaac ttgataatga gattattaat attggaatta
    13141 aagatgaatt tattcctcac ggggatgtta acgtactata tgaacaatgt ggaatctcac
    13201 cttcaggtat agctcaacaa attgagagtt tattaagata gaaaggtaat ttatatgaaa
    13261 aaaagaatag acgtattact tgtagaacaa ggatattttg acagtagaga aagagctaaa
    13321 aaagctataa tggctggact agtatttgta gacaatcaaa gatgtgataa ggctggctca
    13381 gaggttaaag aagaaagtaa aatagaagta aaagggaatc ctataccata tgttagtaga
    13441 ggtggactaa agcttgaaaa ggcaatgaaa aactttgata taacattaga gaacaaagtt
    13501 tgtttagata taggagcatc aacaggtgga tttacagatt gtatgcttca aaatggagca
    13561 aaaaaagtat tttcaataga tgtaggatat ggacaacttg cttggaaact tagacaagat
    13621 gaaagagttg tatgtatgga gagaacaaac ataagacatg taactataga agatactaaa
    13681 gaatttggac aatttgcatc tatagatgtt tcttttatat cacttaaatt agttttacca
    13741 aaagcaaaag aattattaga tccaagtgga caagtagtag cattaataaa acctcaattt
    13801 gaagctggaa gagaaaaagt tggtaaaaaa ggtgtagtaa gagaaaaatc tacacatata
    13861 gaagttatag aaaaagtagc agattttgca gcagaaatcg ggtttacaat attaggatta
    13921 gattactctc ctataaaagg acctgaagga aatattgaat atttaattca tttaaaaaac
    13981 tctaatgaag gttatgaata caataaagaa gagtttaaaa taactataga taaagttgta
    14041 gacaattcac ataatttaat gtaataaaga gggggattta aattgatcct tgaattatat
    14101 atgaaaaact gtgcattaat agaggaacta aggctagata tagacaaaaa tctaaacata
    14161 ttaactggag aaactggatc aggtaaatct ataataatag gagctttagg tttatgtcta
    14221 ggtggtaaat atgatagatc ctttttaaga aaaggcacag aaaaaggttt agtagaagcg
    14281 ttatttgatg ttaataatca aaagcttaaa gagaagctac tagaaaatgg aatagatata
    14341 gaagaggata atcaaataat aataagcaaa gaaatatttg atgacggaaa aagtatatca
    14401 agaataaatg gaagaaatgt aaaagtatca tttttaaaag aaatttctaa ctacttaatt
    14461 gatatacatg gacaacatca aaatcaggtt ttatttgata aagatacaca tattgatttt
    14521 ttagacttat ttggagaaga actcttatat gaatctaaaa gtgattatga aaagacatat
    14581 attgaataca atgaagtaaa aaaagcttta aatgtactaa cagaaaataa agacgatatg
    14641 caaattcaaa gagaaataga tttgataaaa tttcaaataa atgaaataga attagcaaac
    14701 ttaaatgaaa atgaatatga agatttattg aaacaaagag acgtctatag aaatggtgaa
    14761 aagattttta ctaacttaaa taatgcatat ttaaatttat atgatggaag tataaattct
    14821 gtagatctta tatctaaatc actaggtgat ttaggtgcca tagctcaata tgatgaaaaa
    14881 ttaaatgatt ataatgatac aatagagcga ataatgtatg agcttcaaga tatatctaga
    14941 gatattagaa gttataaaga aaacattgat ttttcacctt atgaattaga acaaatagag
    15001 cagagagtag atgaaataaa tactcttaga agaaaatatg gagatacaat agaagaaatt
    15061 ttagcatata aagataaaat aaatgaaaga ttagatgaaa ttttaaatag agatgaaaaa
    15121 gttgaagagt taaaattaaa gcttaaaaaa gtcgaagaca ttttagtaat taaagctgaa
    15181 aaattaactc agaaaagaaa agaagttgca agaaatcttc aagaaaagct attgtatgag
    15241 cttaaaagtt taaacatgaa aaatgtagtt tttgaagttt catttggtaa atctacattt
    15301 aatgcaaaag gacaagatga tatagaattt atgatttcat tcaatctagg tgaagatata
    15361 aagcctatat ataaggtagc atcaggagga gagatgtcta gattcatgtt agcgtttaag
    15421 acgattttag cggacataga tgaaatagat actcttgtgt ttgatgaaat agatacaggt
    15481 ataagtggta tagcagctca gattgttgga gaaaaattat cattgatagc taagaaaaag
    15541 caaataattt gtataacgca tttacctcaa attgcagcaa atgcagacac tcactattgt
    15601 attgagaaaa agacatctaa tgagcgaaca tttactgtta taagtagact tgatgataat
    15661 caaagaaaag atgaaatagc aagacttata gcaggaagta atataactga aaaaacaatg
    15721 gaacatgcta gtgaaataat agaacttgca aaaaaagtac ctaattaatt aggtactttt
    15781 tttgcgtaaa attatattta gattaaactg gataaaaata aatgaaaaat ggaactatat
    15841 gtatataaat ttatgaaggg acgatataaa atgaaaaaaa tatatatagt tttatcttta
    15901 gtcttaataa tacctatatt tatattggga atatcgaaac cagaaaataa aaaagaaaca
    15961 agatatttag ttccacttgg aaatgttgta ggtataaggg ctaacacaga tggaatatta
    16021 gtattagaaa atgaagattc gagtgttgat tatatagatg gagtggaagc tggagataat
    16081 ataattagta taaatggaat taatgtatat agtagtaaag atgtaaaaag agttttacat
    16141 aactataata aagatttagt tgagataata atcgacaggg atggagaact aatatcaaag
    16201 caaattccag ttaaaaaaga aaataacgaa tataaacttg gaatttggat tagagataaa
    16261 atttctggaa taggaactat gacattttat aatccgcaaa acaatacatt ttcggcatta
    16321 ggacatccaa taaaagatat agatacaaat gaattgataa aagttaagag tggaaatata
    16381 tacaatgctg aagacatttc gattgaaaag ggaagagtta aacatgtagg gcaaataaaa
    16441 gctgaatttg atggcgataa accgataggt aattttaaaa aaaataacag ttttggaata
    16501 agtggcaatt taacgacata tgataatgaa ggaaaagaaa aaatgttaga agttggtgac
    16561 agtaaagata taaagcttgg accagcgata attttatttc aaaataaaga tggaaaaatc
    16621 gggcaatatc aaataaacat aaaaaaaatt aaatataata acaaaaaaga tgataaagat
    16681 atggtgattg aagtagtaga tgagagattg ataaattata ctggtggtat agttcaagga
    16741 atgagtggag cacctataat acaaaatgat aaaataattg gggctgttac gcatgttttt
    16801 atagataact ctaaaatagg atatggaatt tttatagata agatgataat ataagtatat
    16861 atataaaaat aaaaataaac agaaggaata taaatattaa atgtcgaata ggttattagt
    16921 gaaaaattag aaaatattta aataaattta taattctatg gggggaaaaa tttaatgagc
    16981 gaaaaaataa aaatagtttt agcagatgac aacagggatt tttgtcaagt attaagagag
    17041 tatttatcta atgaggatga tattgaaata ttaggaattg caaaggatgg aatagaagct
    17101 ttagatttag tttcaagaac acaaccagat gtattagttt tagatgttat aatgccacat
    17161 cttgatggtt taggggtaat tgaaaaacta aatgctatga acttgcctaa aatgcctaag
    17221 ataatagtat tatctgcagt aggtcaagat aaaataacac aaagtgcaat aaacttagga
    17281 gcagactatt acatagttaa accttttgac tttgtaatat ttataaatag aataagagga
    17341 ttagtttcaa ataaaaatac agtagtagat tctaattcaa gatcaaataa taatatggat
    17401 ataaaaatga ctaaaactga tttcgttaaa aatgtaggaa atatagaaac tgaaataaca
    17461 aatataatac acgaaatagg agttccagct catataaaag gatatttata tttaagagaa
    17521 gctataaaaa tggttataga caatgttgaa ttattagggg cagtaacaaa ggaactatac
    17581 ccaagtatag ctaaaaagtt taatacaact ccaagtaggg ttgaaagagc tataagacat
    17641 gcgatagaag ttgcatggag cagaggtaag gttgacacta taaatcaatt atttggatat
    17701 acagttcata atacaaaagg gaaaccaaca aactcagagt ttatagcaat gattgcagat
    17761 aaattaagat tagaacacag tatggttaaa taataaatta tgaaaaacaa agtcttcata
    17821 aattgaaggc tttatttttt tgtgtaaatg tataaaatat atagtaattt actaaactga
    17881 ggtgaaataa tgaaaataaa tataccaact gatgtaaaag agataataga tgatatatat
    17941 gaaaatggat atgaggctta tatagtagga ggatgtgtaa gagactccat tgtaggaata
    18001 aaacctaacg attacgatat aacaacaaat gcaaaaccta cagacacaat aagtatattt
    18061 aaaaattata aaataattga aactggaata aagcatggaa caataacttt aataaaaaat
    18121 aaaaatgaat atgaaattac aacatataga attgatggaa catacgctga caaccgaaga
    18181 cctgaatatg tagagtttac aagggatata atagaagatt taaaaagacg cgattttact
    18241 ataaactcta ttgcctataa tcataaagta ggtatagttg atgcgtttga ggggatagaa
    18301 gatataaata aaaaaataat aagaacagtt ggaaatccag atgaaagatt taaagaggat
    18361 gggcttagga taataagagc tgttagattt agttctaaac ttaatttcaa aatagatagc
    18421 aaaacattgg aaagtattta taaaaatata aaattgataa aaaatataag ctcagaaaga
    18481 atacaagagg aattaaataa aattttactt agtaattatc ctgaaaaaat atatatactt
    18541 tacgatgcaa aaatgtttga tatatttgaa atggaaaatg taaaaatgaa caaaaatgac
    18601 ttagctaaac ttaagtcgag taaaaaagat ttagtgataa gattaagtat atttatatat
    18661 attctagggg acattaacga aagcaaaaaa atattggaat tattaagata ttctaacaaa
    18721 ataaaaagtc aatgcattac aattttagat aagctagata ataaaataat cgatgataaa
    18781 gtgtctataa agatttattt aaaggaaata ggacatgaaa gtctaaatta tctattatat
    18841 gtaaaaaaaa tattggatat agaatttgaa aaaaaatatt atgacaaaat aaataattta
    18901 attaaagaaa ttgatttaaa taaagagtgt tattcattaa aagaattagc actaaatgga
    18961 agggatttaa atgctttagg ctataaaggc aaggaaatag gtgaaaaatt aaacttttta
    19021 ctatataatg tgattgaaaa tcctaatata aacaataaaa cagatttaat taatattata
    19081 aatagcttat aagaagggcg cgtaatttta attatttaaa ttgttgtaaa ataatgctat
    19141 aatgtaatgt gatttcaaaa acgaaaattg gaggttttaa gtatgagagt cgaagcccct
    19201 attaaggtag acagaaaaac aaaaaggctt gcaaagcgac ttactggcgg agaaatagca
    19261 gttataaatc ataaagatgt agatgaagtt gctgcaaatt cattagtaga gggaaagata
    19321 aaacttgtta taaatgcatc tcaatctata agtggtagat acccaaataa aggacctgga
    19381 atacttgtag ataaaaatat acttattgta gacaatgtag gtgaagaact attcaacaac
    19441 ttacaggagg ggcaaataat agaagttata gatggaaaaa tctatagaga tggagaatta
    19501 ttaggccaag gagaagtatt agataaagac gaagttgata acaagataag attggcatat
    19561 gaaaatttgg ctgtagagtt ggatagattt atagataata ctatagatta tgctaaaaaa
    19621 gaaaaaggac ttattcttgg agaagttgaa ataccaaaag taagtacaga ttacaagaat
    19681 agacatgtat tgatagttgt tagaggtcaa gactataagc aagacctaag cacaatatta
    19741 tcgtacatag aagaaatgaa acctatacta gtaggtgtag atggtggagc tgacgcttta
    19801 atagagtttg gatatactcc agacgtaatt gtaggagata tggatagtgt aagtgatgaa
    19861 gctttacaaa aagcaaaaga aatagttgtt catgcataca cagacggaag agcacctgga
    19921 cttaagagag tacaagactt aggattggaa tctgtggtat ttcctgcgcc tggaacaagt
    19981 gaggacatag ctatgcttac tgcttatgag tataaggctg aacttatagt agctgtaggg
    20041 acacattcta atatgataga cttcttagaa aaaggaagac ctggtatggc tagtacattt
    20101 ttagtaagac taaaaatagg atcaaagcta atagatgcaa aaggtgtaaa cttattatat
    20161 agaagtaaat taaaattaaa gtatatatgg gcacttatag caactgcttt attcccagtt
    20221 ttaatacttg catcattctc tccaagtgtt caacaattta tgcacttgat ggaattaaaa
    20281 atgagactac tattacagat gtaattaatt gaggaggatt aacatgcata taaatatgaa
    20341 gtattatata gtaacgatag gtgctatatt tattgcatta ggaataggaa tgctagtagg
    20401 atttaactta aattatgatc aagaacttag caagcaacaa gctgctataa tagatgattt
    20461 agatgctaag tttgaagaca taaaaacaac aaatgatgaa ttagaaggta aactagacaa
    20521 aaaagaaagc gaatacaaaa aactagtaaa ttatttaaat caaaattatt tagtattaat
    20581 aaaagaccaa ttacaaggta aaaatgtagg aataatatca acaacagaaa attatgatta
    20641 tacacaagac atatctaaga ctataacaga tgcaaatgga agtgtagcat atgatattgt
    20701 tttaaaatca gggttaacta acaaagataa aataaaagaa cttgatagtg cattacaatt
    20761 acagttaaaa actgaaaaag atgtagttaa ttacataatg agctgcttaa aagaagaaaa
    20821 tgctatggat aaactacaac aattagaaaa attagagatg ataaaaataa attatttatc
    20881 agataact
//
