LOCUS       NZ_LR607361            20729 bp    DNA     linear   CON 14-FEB-2024
DEFINITION  Enterococcus faecalis strain 4928STDY7387713 chromosome 1.
ACCESSION   NZ_LR607361
VERSION     NZ_LR607361.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecalis
  ORGANISM  Enterococcus faecalis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUL-2019) WTSI, Pathogen Informatics, Wellcome Trust
            Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/14/2024 00:48:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,659
            CDSs (total)                      :: 2,598
            Genes (coding)                    :: 2,566
            CDSs (with protein)               :: 2,566
            Genes (RNA)                       :: 61
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 32
            CDSs (without protein)            :: 32
            Pseudo Genes (ambiguous residues) :: 0 of 32
            Pseudo Genes (frameshifted)       :: 14 of 32
            Pseudo Genes (incomplete)         :: 15 of 32
            Pseudo Genes (internal stop)      :: 7 of 32
            Pseudo Genes (multiple problems)  :: 4 of 32
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:58:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1777290
            Orig. end                         :: 1798019
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR607361.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20729
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="2"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     cand_cluster    1..20729
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20729
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10729](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10729)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     misc_feature    107..122
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: strong, score: 28.99"
                     /tool="antismash"
     misc_feature    578..592
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.08"
                     /tool="antismash"
     gene            complement(1997..3385)
                     /locus_tag="FN738_RS07355"
     CDS             complement(1997..3385)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010712556.1"
                     /locus_tag="FN738_RS07355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_010707478.1"
                     /transl_table=11
                     /translation="MIDRKKVILYTCCMSLFVVTMDVTVVNVALPSIQSDFHTNLSTLQ
                     WVTDGYTLMVASLLLLSGSTADRIGRKRVLQLGLACFGLASFLCGISQTPGQLIAFRML
                     QGIGGSMLNPVAMSIITQVFTEKLERAKAIGLWGSVTGISLGMGPIIGGLIVSYFSWRY
                     VFFVNVPIIAAAIILTQKFVPESKVEKTVKNDFVGQALMILFLFSSIYSIIGLPRKGLF
                     APDILSTGIIGCLAIVIFFIYEYNIDNPLINPRFFLSIPFTSASFLAIFGFIIYNGYLF
                     LNTLYLQEMRGFSPLEAGLSTIPLAFVSFLVAPRAGEMVGRIGTKRPIMLCGISMLAVS
                     FLQLFVTKTTPMIILFVIYIFLGIGFGMLNSPITITAIEGMPLSQSGTAAAIAVTCKQI
                     GNSLGVALPSLLITKPITSSLTRTPFTNVWLLFGCCAIAIIFLSYLSNSPLAKKSLRRV
                     RFYF"
     misc_feature    complement(3647..3663)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            complement(3767..4621)
                     /locus_tag="FN738_RS07360"
     CDS             complement(3767..4621)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010821679.1"
                     /locus_tag="FN738_RS07360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_049095606.1"
                     /transl_table=11
                     /translation="MTIEKLEYFYTIAKYNSISKAASELHVSKSTLSASLKDLESELGH
                     LLFDRNGNSLTLNSYGDKIVQSVYIILNEAKKMKLNLHEMIENPVMRLGFGNTSLMYKV
                     TENDDQLNRFWECYHGSSFELLNKLENHELDFVITSADVNSPVLKKEQLIELKMYLCVS
                     REIKQEIEEEGFTCLTNYPFLFLPHHLDHLEATKSVLEMLQLTSPLVCCYDTLMLTRLI
                     EKSKGVYAVISLRKEQLQEIDSKLFFLPIERKQKFYLYRNVSSSVFVQPGQIKATLQKL
                     LET"
     gene            5013..5843
                     /locus_tag="FN738_RS07365"
     CDS             5013..5843
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397393.1"
                     /locus_tag="FN738_RS07365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_002360106.1"
                     /transl_table=11
                     /translation="MKINYLGTGAAERIPGIFCNCKLCKYAREKKGREIRTQTQLIIDD
                     VLLIDFPGDSYLHLLQYDLCFADFDSLLISHWHSDHFYGEDLAYRMSGYALDIPNRLTV
                     YGNEAVKTFYQRAFDLEGRQDDTRLQYQVIQPYKCFTIANYTIYPLPAQHGNFSEDCFI
                     FVIDDGKDAFLSTHDTGYFTSEMFEYLEKSHLLLSIVSLDCTSQTNETGNSHMNWEENL
                     KLIAELKERKLVTDKTIYVANHFSHNGGLSYAEMAALSQKHEIITSYDGLEILT"
     gene            complement(5991..6845)
                     /gene="sprE"
                     /locus_tag="FN738_RS07370"
     CDS             complement(5991..6845)
                     /codon_start=1
                     /gene="sprE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364098.1"
                     /locus_tag="FN738_RS07370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine proteinase SprE"
                     /protein_id="WP_080120423.1"
                     /transl_table=11
                     /translation="MKKFSIRKISAGFLFLILVSLIAGFSLSANAEEYIVPAESHSRQK
                     RSLLDPEDRRQEVADTTEAPFASIGRIISPASKPGYISLGTGFVVGTNTIVTNNHVAES
                     FKNAKVLNPNAKDDAWFYPGRDGSATPFGKFKVIDVAFSPNADIAVVTVGKQNDRPDGP
                     ELGEILTPFVLKKFESSDTHVTISGYPGEKNHTQWSHENDLFTSNFTDLENPLLFYDID
                     TTGGQSGSPIYNDQFEVVGVHSNGGIKQTGNHGQRLNEVNYNFIVNRVNEEENKRLSAV
                     PAA"
     gene            complement(6894..8426)
                     /gene="gelE"
                     /locus_tag="FN738_RS07375"
     CDS             complement(6894..8426)
                     /EC_number="3.4.24.30"
                     /codon_start=1
                     /gene="gelE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369251.1"
                     /locus_tag="FN738_RS07375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M4 family metallopeptidase coccolysin"
                     /protein_id="WP_142963641.1"
                     /transl_table=11
                     /translation="MMKGNKILYILGTGIFVGSSCLFSSLFVAAEEQVYSESEVSTVLS
                     KLEKEAISEAAAEQYTVVDRKEDAWGMKHLKLEKQTEGVTVDSDNVIIHLDKNGAVTSV
                     TGNPVDQVVKIQSVDAIGEEGVKKIIASDNPETKDLVFLAIDKRVNNEGQLFYKVRVTS
                     SPTGDPVSLVYKVNATDGTIMEKQDLTEHVGSEVTLKNSFQVAFNVPVEKNNTGIALHG
                     TDNTGVYHAVVDGKNNYSIIQAPSLATLNQNAVDAYTHGKFVKTYYEDHFQRHSIDDRG
                     MPILSVVDEQHPDAYDNAFWDGKAMRYGETSTPTGKTYASSLDVVGHEMTHGVTEHTAG
                     LEYLGQSGALNESYSDLMGYIISGASNPEIGADTQSVDRKTGIRNLQTPSKHGQPETMA
                     QYDDRARYKGTPYYDQGGVHYNSGIINRIGYTIIQNLGIEKAQTIFYSSLVNYLTPKAQ
                     FSDARDAMLAAAKVQYGDEAASVVSAAFNSAGIGAKEDIQVNQPSESVLVNE"
     misc_feature    complement(8640..8655)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.19"
                     /tool="antismash"
     gene            complement(8661..10004)
                     /gene="fsrC"
                     /locus_tag="FN738_RS07380"
     CDS             complement(8661..10004)
                     /codon_start=1
                     /gene="fsrC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402207.1"
                     /locus_tag="FN738_RS07380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase FsrC"
                     /protein_id="WP_142963642.1"
                     /transl_table=11
                     /translation="MILSLLATNVLLASSFIVFVFLRVTLIKIECKIPSLSLLIVINLC
                     SFAALMLGYSWLIYALTVVIFTGFLLIHKKRFSIFKAIFLSVFTLLMVSFINYTEQTIL
                     SVFFQQIYQNKLLWIASNVLLLLINIWIALKIPNSVFLRLNRVLENSRIFFGCLLLLLI
                     LLLLFVFLISPEISPDFMRGFVTVNSSKLELLISVGLFLILIGLVIEAYLEEQRINTQL
                     LNNLTIYTEKIESINEELAMFRHDYKNLLYSLQIAISYEDILEIKRIYEETIAPTKKII
                     DNEEFELMKLNRLKNMELKALISMKINTAKQAKLKVIVDVPEVFILDTSIDLVVVIRLL
                     AILLDNAIENSAKSELKMFAISIFNKNETQEFVITNSVQAEFDFRVMKKTKFSSKSNPE
                     EHGWGLLYVKEIVDFSDQFDLQTSFNEGSVTQHLIIEKNHNSKKVVNE"
     gene            complement(10001..10729)
                     /locus_tag="FN738_RS07385"
     CDS             complement(10001..10729)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634271.1"
                     /locus_tag="FN738_RS07385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="accessory gene regulator AgrB"
                     /protein_id="WP_002408849.1"
                     /sec_met_domain="AgrB (E-value: 2.6e-31, bitscore: 105.7,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIDWILKNIMDMDQEDQSGKTQWTKYYLTVYFSGLFNFLMILIL
                     SVLFGTLSETFIVYVILIFLRPVAGGWHAKTKWLCRLESIVIYVAIPFVLKNSSVSLPF
                     IYKILLMCLLVVLFYWYAPQGTAIEPVQPSDLNVLKKQSLIRVCLLILCSLFVKEKIAS
                     VILYGLVIQGLMILPVTKNLIEGSVFMKFGKKIIKNVIEKRVAKVSDGVGTKPRLNQNS
                     PNIFGQWMGQTEKPKKNIEK"
     gene            complement(10818..11549)
                     /gene="fsrA"
                     /locus_tag="FN738_RS07390"
     CDS             complement(10818..11549)
                     /codon_start=1
                     /gene="fsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109506.1"
                     /locus_tag="FN738_RS07390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator FsrA"
                     /protein_id="WP_073340375.1"
                     /transl_table=11
                     /translation="MAIYILEDQIIQAKALEALVTNILHSRNIYNETIHLFSRSDELLQ
                     VAHQDAQLNIFFLDIQMNNHIQAGFEVAKEIRKTDSESLIVFISTHTELVLTSYKYMVS
                     ALQFIQKNVDFLDFQKEVETCVDAYIQQKENIKTKSEYIIINLKASSIKMDINDIYFFQ
                     TEYDHRVSMVGKNFKREFYGTLSKIEQLHPDLIRVHQSIIINKKYASKLNYKTHLLTMR
                     DGTEVPVSRRYYTQVKALFLT"
     misc_feature    11661..11676
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.55"
                     /tool="antismash"
     gene            complement(11968..13926)
                     /locus_tag="FN738_RS07395"
     CDS             complement(11968..13926)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401391.1"
                     /locus_tag="FN738_RS07395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amidase domain-containing protein"
                     /protein_id="WP_142963643.1"
                     /transl_table=11
                     /translation="MKRKKIKNQLLVLTSILVLLSLEVAPVVTLAAELPSSSLQTALSS
                     ATTITSEEKVTETTETTVATSTTSTSSSSSESSSSTDTTTESTSQSMTETTTTNTSSET
                     KKEPTESTVSSEITQPVEQSQPPQVPVTKQEPEEPIQVPEATNNVVEENQAVSLNPSLK
                     VDEIASSNLKGYELPLLSSFDEQKRAVVVAEALRHVGKTKKEFNLTEQALTSSFLAQKI
                     YQQLFKIDIGSTPQEQMTFGKVRSIEEAEPGDLIFWQTAEGKTLQNGVYLGQGKYLIAA
                     AESDSKEKPEVIAQLENIYTAKQQPDSKEEKRLVVTNPFKEFTLTEYGKEVLTTYGASF
                     EMQKSEQTTAFIKKIGETARELGEKYDVFASVMIAQAILESGSGESQLAKEPYYNLFGV
                     KGSFQGNSVSFSTKEADQRGQLYTISAGFRDYGGYNDSLQDYVQLLRQGIDGNQDFYKP
                     AWRSEAKNYLQATRFLTGKYATDKQYDNKLNSLIAVYNLTQFDLPKTVDGLIIQSKNEL
                     SEAEQQQMHFPVYDGINYNRSGSYPVGQCTWYVYNRFKQLGTSVDEFMGNGSDWGRKGR
                     ALGYQVSSLPKAGRAISFQPGVAGADNQYGHVAFVEAVTSDGIIISESNVINDQTISYR
                     VLPNVIAYSSGVTYIGA"
     gene            complement(14008..19635)
                     /locus_tag="FN738_RS07400"
     CDS             complement(14008..19635)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633936.1"
                     /locus_tag="FN738_RS07400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="WP_172616647.1"
                     /transl_table=11
                     /translation="MGSNFKEEKMNKEYQGKKIYGKKHWLTFLLVSSSVLAFHSFVTMD
                     SQVVDAQEQTAKEDVADSATSVGAIVSIEKAEKNFVITYASGKKAQISILNDHLFRYHL
                     DPTGKFEEYPTPNDPKHVAKITAKTMADYGTQAFEQTNVTDSGNQFTLENNGLKIIFEK
                     ESALMKVLDKKKDQVILEETAPLSFKNDKATQTLKQSSQENYFGGGTQNGRFTHKGTAI
                     QIVNTNNWVDGGVASPNPFYWSTAGYGVVRNTWKPGNYDFGSHDPQTTTTTHEGTDFDA
                     FYFFNDSSAGILKDYYELTGKPALMPEYGFYEAHLNAYNRDYWVKVAEGTAGAVKFEDG
                     NFYKEYQPGDLGNLNGTLESLNGEKENYQFSARAVIDRYKKNDMPLGWFLPNDGYGAGY
                     GQTDSLDGDVQNLKEFTDYAQANGVEVGLWTQSNLHPADPKNPKKGERDIAKEVSVAGV
                     KALKTDVAWVGYGYSFGLNGVEDAANVFVKETDGAVRPMIVSLDGWAGTQRHAGIWTGD
                     QTGGQWEYIRFHIPTYIGTSLSGQPNVGSDMDGIFGGKNKEVNIRDFQWKTFTPVQLNM
                     DGWGSNPKTPFAFDQEATDLNRAYLKLKSMMMPYNYSIAKESVDGLPMVRAMALEFPNE
                     GTAYTKDSQYQYMWGPNLLVAPIYNGNQDEAGNSIRDGIYLPDEKQVWVDLFTGEKYQG
                     GRVLNGVKTPLWKVPVFVKDGSIIPMTNPNNNPKEIQRDQRSFLIYPNGTTSFNMYEDD
                     GISTSYEAGQSATTKINSQGPKSNEKGDLTVTIEPTKGSYKDFVDERSTTLDLLASEAP
                     ESVTAMVGGTEVTLKQAANKEEFLAGTNLYYFDKEFQVNQYLSEASGEKLNQSALSVKL
                     AKQSVTAKDVQITVKGFINKGTVDGGNTTVDDQLTIPANVAINEEKTTPSSLTLQWDQV
                     TEATSYEVERDGTVFGNIQTNTATFDGFSFLSEHTFRVRAVGKNGVSEWSEPIKGKTQD
                     DPYKETINQVKATSNLPEQPGAELKKLTDKDLSTGWHTNWSTGIANPSDGNFLTLKFDL
                     GAEYQMDKIEYLPRDNAGNGNILQLQYRTSKDGANWTEFSEPINWKQDALTKTIETKDQ
                     AYRFVEIKVLKSVGNFGSGREMLFYKQPGTEGILHGDITNDGTIDENDAMSYRNYTGLE
                     SVDSDFNGYVEKGDLNKNGLIDAYDISYVLRQLDGGIEIPDVEEIAGGLSLAVVNENGK
                     DTYLPGDTLTFTLKGQDLKNINALSTKMSFDSSKFELVGQPATTNNTKQMENYSKYRKH
                     SNDVENLYLVLSNQGNKQLLNGSMDLVTFKVKVKETTRVKRATTVEQSLQFDMSQGLLV
                     GQGFQQATLSDFSVTVKPTELVDKELLQALITLNQARVEKEYTPETWAIFKPILDEAVA
                     VLANEQATQTDVSAAVENLEKAVEQLEKMPDVANKADLEKAIQEGLTKKPSDGQEFTEE
                     TKKVLEESLAAAQKVFAQEKVTQEEIDQATKTLREAIAQLKEQPVAVDKETLKEKIAQA
                     RGRKPEEGYQFTKETEKQLQEAIQAAEAIVAKETATKEEVSEALNALETAMAQLKEVPL
                     VNKDQLQEVVKRAQQVTPSEGHQFTASSLQDLQKVLLAAKNTLENPAANQKMIDEAVAE
                     LTSAIEGLQEEALVTDKKALEAMIAKAKAIKPSAGKEFTSESKARLTEAIDQAEGILAD
                     KNARQDQIDIAEKNVKTALDSLEEQVLQTDKTKLKELLQKAETLKPKAGKQFTKASQEA
                     LAEAIKQAKALVEDPNATQEAVDKCLSILAQAIEAMAEEPISSNSTGNNGNHGTVSGTG
                     GVTSPGKGTTTGGTTTKTTTSGTLPKANEVVSPIWSISGFLLIVSIGLGKLFFKNKKDQ
                     N"
     gene            complement(20140..20535)
                     /locus_tag="FN738_RS07405"
     CDS             complement(20140..20535)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407764.1"
                     /locus_tag="FN738_RS07405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002361986.1"
                     /transl_table=11
                     /translation="MDGMFANLTLRERRLLKQAQVGATISFILLFVPILTISLLHTSDL
                     LAKWLGIVGVIMVLPLLYFAWQILKIAYKDQKDNPTPPLWVPKVYGIGLSINPYHRFGK
                     LIFILLAVLIVGIIISLLFTPASQINH"
     misc_feature    complement(20682..20696)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.5"
                     /tool="antismash"
ORIGIN
        1 ttttcaaaag ctacatcata gttgtagtcc tttggttgca cttcttggaa tccttgtggt
       61 ttataaaaac gtaaaaggtt ttcctgattt aatttgtcag ataaacttaa cgattttttc
      121 acccaatcgt tatctttcgt aacttctgct tttaaatctg ctggaacttg gtctaatttt
      181 ttcccttgat tattgtagat ttccccacct agatacgaaa attgaggcgt tacaaaatcg
      241 ccatttctaa aaggaaccac ttgtttatat tgaggagata aaaggtccgt gccaaaatgg
      301 atataatttt tatcatcgac acctaaaaga tggtacagtg tcggtaaaac gtcaatttcc
      361 ccaccatatt cgtgcatgat tttcccttgc gtatagcctg gcatgtaaaa catcaaaggt
      421 actctttgca attgcgcatt gtcatagttt gtccacgttt ttggatcgcg gttgaaggct
      481 ttacataagt ccttgttgtt cgcatctgaa ataccgaagt ggtcaccata aataacaaaa
      541 atagaatgat tgtataaact tgttgtttgc aagtaatgga aaaattgttc tagcgattga
      601 tccaaatagt gcgctgttcg aacataatca tccacaatcg aattgcctgt gttcaattta
      661 ggaaacggga agttttggtc atccgtataa taaggggtat gattggtcac agttaaaaac
      721 ttcgcataga atggctgctg taaatgctca agctcactag ctgattcacg caacaattgt
      781 ttatctaaaa taccgtaacc tagcattttg tcatcttttg aaaaatatga ccgatcaaaa
      841 aagtattgat atcctaagtt tttatacaca tggtctcgat tccaaaaact ccccacattt
      901 ccatggaaaa cagcggttgt atagcctttt tgtcctaaaa ctgcgggagc cgcttcgaaa
      961 gtattgtctg atcctaattg tgtaaaaaga gagccttgcg ggagcccgaa tgttcctgtt
     1021 tctaacatgt tctccgcatc actcgttttt ccttgcccta cttcatgaaa gaaattatca
     1081 aaactgattg tcgctttgtt ttgatagagc tgatttaaaa acggtgtaac ctcttggcct
     1141 tggactttca tattaatcaa aaattgttga aaactttcta aatgaatcac aaatacattt
     1201 tttcctttgg caatcccggc atactgcgga ttaagcggta aattgttttg cttggtaaat
     1261 ttcatgattt caggtaattc gtttgaacta gcttctgctc ttacctcatt tgacatggct
     1321 gttttgacac catcgatggc tgtgaatgca tccaagccaa gatattttac aatataatta
     1381 cgatcaaaaa ttctttgaag caattgagga cgatcggttt cgcttaaaaa taagttaacc
     1441 gaaaagagca agacacttaa acaactaatt gagatcgcca atcttctgtt gataggtttg
     1501 gtcacaaaga cttgatgatt ccgtcgctgt ttaaaagagt aaaataccaa aacgagcagc
     1561 actaaagcat ctagccaata aaagacatcg tggactctca ttaaagcaag taaatcacca
     1621 gaaatccctt ctgaaacttt tgaaaagcca aaaacagatt ggatggtaat aaagtcagtg
     1681 aattcacgat aaaaaataat attcaaatat aaaattaatg tatttaaaac atttaaaaga
     1741 gttaagctaa gcataaatgt tttatgcttt ttaaaataca aactaaaacc aaataataac
     1801 agcgtagtag caactggatt gaaccacaaa atttctcgtt ggagactgcc cttaacgccc
     1861 aatgagaaat ctaggtaata cgccagaatc gtttttgccc aaaagagtaa aacaaaaaat
     1921 aaaaagagtc ctaatcggtt atttattttt ttcatctaac tttgtcttcc tttcccttca
     1981 aaaaaatctt gatttattaa aaataaaacc taactctgcg caatgacttt ttcgctagcg
     2041 gagaattgga taaataactt aaaaagataa tcgcaatggc gcaacatcca aataaaagcc
     2101 atacgtttgt aaaaggtgtt cgagtaagcg aactagtaat aggctttgta attaaaagac
     2161 ttggtagcgc cacccctaaa gaattgccaa tttgcttaca tgtcaccgca atggctgctg
     2221 ccgttcctga ctgagaaagt ggcattcctt caatcgctgt aatggtaatc ggtgaattta
     2281 acatcccaaa cccaatgcct aaaaagatat aaataacaaa taaaataatc ataggcgttg
     2341 ttttagttac aaataattgt aaaaagctaa cagccaacat tgaaatacca caaagcataa
     2401 taggacgttt cgtccctatt ctccctacca tttcgccggc tctcggggca acaagaaaac
     2461 taacaaaagc caaaggaatg gttgataagc cagcttccaa cgggctgaag cctctcattt
     2521 cttgcaaata tagcgtgttt aaaaataaat aaccgttata tatgataaag ccaaaaatag
     2581 ctaaaaaaga agccgatgta aagggaatag ataaaaagaa gcgcggattg attaacggat
     2641 tgtcaatgtt atattcataa ataaagaaaa taacaatggc taagcagccg attatcccag
     2701 tacttaaaat atctggcgcg aaaagccctt ttctaggtag tccgataatg gaatagatag
     2761 aactaaatag aaaaagaatc atcaatgctt gaccaacaaa atcatttttc accgtcttct
     2821 ctacttttga ctcaggtaca aacttttgtg taaggatgat tgccgcagca atgatcggta
     2881 cattgacaaa aaagacatac cgccagctaa aataagaaac aatcagtccg ccaataatcg
     2941 ggcccattcc taaggaaatc cctgtaacag agccccacaa gccaattgct ttcgctcgtt
     3001 ctaacttttc ggtaaatacc tgtgtaataa tagacattgc taccggattt aacatagaac
     3061 caccaatccc ttgcaacatg cgaaacgcaa tcaattgccc tggggtttgc gaaatcccac
     3121 ataggaaaga cgctaaacca aaacaggcta agcccaattg aaggactcgt ttacggccaa
     3181 ttcggtctgc tgtagaccca gataacaata ataaggatgc taccattaaa gtgtagccat
     3241 ctgttaccca ctgtaatgta gacagattcg tgtgaaaatc actttgaatg gatggtaacg
     3301 ccacattgac aaccgtaaca tccatggtca ctacaaacaa actcatgcaa caagtataca
     3361 aaataacttt ttttctatcg atcataaaaa cagtcctttc tagcaactac ataaaacagg
     3421 aaaagcaaca atgacactta aacttctaac gacacagtta tcgcaagtac tcacgtatca
     3481 acagttcttt atattccttg ccatttagtt attttatact taaaaaaata aatctttaga
     3541 tagccaaact atacaccaga acccctttaa attgaaccgt aatagatacg atttatcgat
     3601 tcttaagtta ttaaataatt gaacattccg ttcagaaata tcgaacagcc ccataattga
     3661 gcatctcttt taaacaatga acaacaaaaa tagccttatc cgcagcagaa gtaaatctaa
     3721 gcgaataaag ctatttttgg taactattcc aaagtaattt taatggctaa gtctctagca
     3781 acttttgtaa agttgccttg atttgaccag gttggacaaa aaccgaactg gaaacatttc
     3841 ggtataaata aaatttttgt tttcgttcaa tcggtaaaaa gaagagttta gaatcaattt
     3901 cctgcagttg ttctttccga agagagatca ccgcataaac tcctttactt ttttcaatga
     3961 gacgagtaag catcaacgta tcgtagcaac aaacaagcgg acttgttaat tgcaacattt
     4021 ctagcacgct cttggtagct tctaaatgat ctaagtgatg cggcaaaaat agaaatggat
     4081 agttggtcaa acaggtgaag ccttcttcct caatttcttg tttaatttct cttgaaacac
     4141 aaagatacat ttttagttca attaattgtt ctttctttaa aactggacta ttcacatctg
     4201 cagaagtaat cacaaaatcc aactcatgat tctccaattt attcaataac tcaaacgatg
     4261 aaccatggta acattcccaa aaacgattca gttgatcatc attttctgtc actttataca
     4321 tcaaggacgt atttccaaaa cctaaacgca tcactggatt ctcaatcatt tcatgcaaat
     4381 taagtttcat tttcttggcc tcgtttaaaa tgatatatac agattggacg attttatccc
     4441 cataggaatt taacgtcaaa gaattaccgt tacggtcaaa aagtaaatgg cccaattcac
     4501 tttccaaatc ttttaatgac gcacttaagg ttgatttact aacatggagt tcagaggctg
     4561 ctttggaaat actattatat tttgcaatgg tataaaaata ttctaatttt tcaatagtca
     4621 tcttttgtca tcccttttat tcaaattcat ttgcccacgc aacctgttca aaacacgcct
     4681 cactctttat caatagcgta gttatttttg ctctaataag ctatgtccat cttgttattt
     4741 ttctataact aatagtagat gaatatgaaa gtgcctttgg taaaactttt tctcggaaat
     4801 agcatgaaca ttcgcaacaa attcagctta ttaaaaaagg cgtctagctt tttctatttt
     4861 acgcaaattt acttaagaaa ttccatttca attcttctct aaaaaaggta agatggacac
     4921 aacaaatgtt tcagtttcca tgcccattta ctttaaggtt cagcgttatc tactaagtat
     4981 gaagaatgtc aaagaaaggt taggtactcc caatgaaaat caactattta ggtacgggtg
     5041 cagcagaacg gattccagga attttttgta attgtaaatt atgtaagtac gctcgagaga
     5101 aaaaaggacg agaaattcgt acacaaactc aattaattat tgatgatgtc ctgctgattg
     5161 attttccagg ggattcttat ttacacttgt tgcagtatga cttgtgtttt gcagactttg
     5221 actctttact aatctctcat tggcattccg atcattttta cggcgaggat ttggcttatc
     5281 gaatgtctgg ttatgcatta gatattccca atcgtttaac tgtttacgga aatgaagcag
     5341 ttaagacgtt ttatcagcgc gcctttgatt tagaaggtcg ccaagacgat acccgattac
     5401 agtatcaggt tattcagccc tacaaatgtt ttactattgc gaactatacg atttatcccc
     5461 ttcctgcaca acatggaaat ttcagtgaag attgttttat tttcgttata gacgatggta
     5521 aagatgcttt tttatccacc catgatacag gttactttac gtcagaaatg tttgaatatc
     5581 ttgaaaagag ccacttactt cttagtattg tttctttaga ttgtactagc caaacaaacg
     5641 aaactggcaa tagtcatatg aattgggaag aaaatttaaa attaattgca gaattaaaag
     5701 aaagaaaact cgtcacagat aaaacgattt acgttgccaa ccatttttct cacaatggcg
     5761 gcttgtctta tgcggagatg gcggctttat ctcaaaagca tgaaatcatt acgagttatg
     5821 atggtttaga aatactaact taatcggatt atttgccttc ttttcagcac tattatatgc
     5881 ttttaaccga taattacaag gtgcttttat cgtaacttac actatcttaa aaaacaaaaa
     5941 tactcgagat ttcccgtgat tctggaaatt ccgagtattt ttatggttct ttacgctgct
     6001 ggcacagcgg ataaacgttt attttcttct tcattcactc gattgacaat aaagttataa
     6061 ttcacttcat ttagtctttg accatggttt cctgtttgct taatgccacc attggaatga
     6121 acaccaacta cttcaaactg atcattatag attggtgaac cagattgacc acctgttgta
     6181 tcgatatcat aaaatagtaa tggattttct aagtctgtaa agttagatgt aaacaaatca
     6241 ttttcatgag accattgtgt gtggtttttc tcacctggat agcctgatat tgtgacatgg
     6301 gtatctgaag attcaaactt tttcaaaaca aatggcgtta aaatttctcc caactctggg
     6361 ccatctggac gatcgttttg tttgccgaca gtcactaccg caatatccgc attcggggaa
     6421 aaagctacat caatcacttt gaatttgcca aatggtgtcg cactgccatc tcgacctgga
     6481 taaaaccaag catcatcttt ggcattcgga tttaatactt tggcattctt aaaactttca
     6541 gccacatgat tattggtgac aattgtatta gttccaacaa caaagcctgt tcctaaagaa
     6601 atatagcctg gtttactggc aggggaaatg attcttccga ttgacgcaaa aggcgcttcg
     6661 gttgtatctg ccacttcttg tcttctgtct tcagggtcca gtaacgatct tttttgtcgt
     6721 gaatgacttt cggcaggaac gatatactct tctgcatttg cagagaggct aaaaccagct
     6781 atcaaactta ctaaaatcag aaacaaaaaa ccagcactaa tttttcgtat ggagaacttt
     6841 ttcataagat tatgccactc cttatccatt tttatttaat tggggaattt ttttcattca
     6901 ttgaccagaa cagattcact tggttggttt acttgaatat cctctttagc tccgattcca
     6961 gcagagttaa aggctgctga caccactgaa gctgcttcat cgccatattg aacttttgca
     7021 gcagcaagca tcgcatcacg agcatcactg aattgtgctt taggtgttaa gtaatttact
     7081 aatgagctgt agaaaatagt ctgtgctttt tcaatgccta aattctggat aatggtgtaa
     7141 ccaatccgat taataattcc actattataa tgaacaccac cttgatcata ataaggcgtt
     7201 cctttatatc gtgctcgatc gtcgtattga gccatggttt ctggttgtcc gtgtttactt
     7261 ggtgtttgta aatttcgaat acctgttttt cggtcaacac tctgagtatc cgcaccaatt
     7321 tctggattag atgcacccga aataatataa cccatcaaat cagaataaga ttcattcaac
     7381 gcacctgatt gtcctaaata ttctaaaccg gcagtatgtt ccgtcacacc atgtgtcatt
     7441 tcatgaccaa ctacatctaa agaggaagca tacgtttttc ctgttggtgt acttgtttca
     7501 ccataacgca ttgcttttcc atcccaaaaa gcattgtcat aagcatctgg atgttgttca
     7561 tcaacaactg acaagatggg catccctcga tcatcaatac tgtgtcgttg gaaatgatct
     7621 tcataatatg ttttcacaaa ttttccatgc gtataggcgt caacagcatt ctgatttaat
     7681 gtcgctagtg atggtgcttg aataatagaa taattatttt tgccatcaac tactgcatgg
     7741 taaacccctg tgttatccgt tccgtgtaaa gcaattcccg tattgttttt ttcaactggc
     7801 acattaaacg ctacttgaaa agagtttttt aacgttactt cactaccgac atgttccgtt
     7861 aaatcttgtt tttccataat tgttccatct gtagcgttca ctttataaac caatgatacg
     7921 gggtcaccag ttggcgaaga agttactctg actttataaa ataattgccc ctcattattt
     7981 acacgtttgt caatagctaa aaagacaaga tctttagttt ccggattatc agaagcaata
     8041 atttttttaa ctccttcttc accgattgca tcaaccgatt gaattttcac tacttgatca
     8101 actggatttc ctgtaacact tgttactgca ccatttttat ctaaatgaat aatcacatta
     8161 tctgaatcaa cagtaacgcc ttccgtttgc ttttctaatt taagatgctt catcccccac
     8221 gcatcttctt ttcgatctac aaccgtatat tgttcagcag ctgcctcaga aattgcctcc
     8281 ttttccaact tcgataaaac tgttgaaact tcactttctg aataaacttg ttcttctgct
     8341 gctacaaaaa gtgaagaaaa tagacatgaa cttccaacaa agatgcctgt acctaaaatg
     8401 tataaaattt tatttccctt catcaaacga ttaactcctt ccccagtttc cttttatttc
     8461 ttttcccaac aaaagtattg ctttatcctc cctaatcttt cccgttaaac gactgctcct
     8521 ttccctgcgt aaatatttgt tgctattttc attatagaca actacctaac cggcactatc
     8581 taaattcctt aatcagccga catttttccc tgtattgccc ctcatatctc aataccatag
     8641 taaaaaagtt gttaacaaat tcattcgtta acaacttttt tactgttatg atttttttca
     8701 ataattaaat gttgagtaac cgatccttca ttgaaggacg tttgcaaatc aaattgatct
     8761 gaaaaatcaa caatttcttt tacgtataac aatccccaac cgtgctcttc agggttactt
     8821 ttagaactaa atttggtttt cttcataacc ctaaaatcaa attcggcttg gacactattt
     8881 gttatcacaa actcttgtgt ttcattttta ttgaaaattg agatagcgaa cattttcaat
     8941 tctgattttg cactgttttc aatcgcgtta tctaatagaa tagccaacaa acgaatcaca
     9001 accactaagt cgattgatgt atcaagaata aatacttctg gcacatcaac aatcactttt
     9061 agttttgctt gctttgcggt attaattttc atacttatga gtgccttaag ttccatattt
     9121 ttcaaacgat ttaacttcat aagttcaaat tcttcattat caataatttt tttggttggt
     9181 gcaatcgttt cttcataaat tcttttgatt tccagaatat cttcgtatga aatagcaatt
     9241 tgtaaactat acaataaatt tttataatca tgacgaaaca tcgctagctc ttcgttaatg
     9301 gattctattt tttcagtata aatcgttaaa ttattcaata attgagtgtt gatacgttgt
     9361 tcttccaaat aagcttcaat gactaagcca atcagaatta aaaataaacc tacacttatt
     9421 aataactcca atttagaact atttaccgtg acaaatcctc gcataaagtc aggtgaaatc
     9481 tctggcgaaa tcaaaaacac aaaaagtaac aacagaatca acaataaaag taaacaacca
     9541 aaaaaaattc ggctattttc taacacacga tttaatctta aaaaaacact attgggaatt
     9601 tttaaagcaa tccagatatt tataagcaac agaagaacat ttgaggcaat ccataataat
     9661 ttattttgat aaatctgttg aaaaaaaaca cttaaaatcg tttgctccgt gtaattgata
     9721 aacgaaacca taagcaatgt aaaaacggat aaaaatatcg ctttaaaaat tgagaacctc
     9781 tttttgtgaa tgagtaaaaa tcctgtaaaa ataacgactg tcagcgcata aatcaaccaa
     9841 gagtagccca acattaatgc cgcaaacgaa caaagattaa tgacaataag caatgaaagt
     9901 gacggtattt tacattcaat cttgatcaat gttactcgta aaaagacaaa aacgataaag
     9961 ctagatgcca gcaaaacgtt agtagctaat aacgacaaaa tcatttttca atattctttt
    10021 taggtttttc agtttgtccc atccattgtc caaatatatt gggcgaattt tgatttaatc
    10081 taggcttagt tcccacacca tcactgactt ttgcaactct tttttcaata acatttttaa
    10141 ttattttttt accaaatttc ataaaaacac ttccttcaat taaatttttt gttacaggga
    10201 gtatcatcag accttggatg acgagaccgt agagtattac tgaagcaatc ttttctttga
    10261 caaacagact acataaaata agtaaacaca cccttataag gctttgcttt ttgagcacgt
    10321 ttaaatcaga tggctgaaca ggttcaattg ctgttccttg tggcgcatac caataaaata
    10381 atacgactaa gaggcacatc aatagaattt tataaataaa cggtaagctc acagaagaat
    10441 ttttcaatac aaatggtatg gcaacataga taacaatgct ttctagacga cagagccatt
    10501 tagtttttgc atgccagcca cctgcgacag gccgtaaaaa aatcagtatg acgtatacaa
    10561 taaaggtttc gcttaacgtc ccaaataaaa ctgataaaat cagaatcatc agaaaattaa
    10621 ataagccaga aaaataaacg gttagataat actttgtcca ttgtgttttt cctgattgat
    10681 cttcctgatc catatccata atatttttta gaatccaatc gattagcata tcgccctcct
    10741 cttcaagtat tgcactaaat tataacgaat atagcgacta atagatagat aattccttaa
    10801 ttagtcatta tccctcccta agtaagaaat agcgccttga cctgagtata atatcttctt
    10861 gagactggta cttccgttcc gtctctcata gttaaaagat gcgttttata atttaatttt
    10921 gacgcatatt ttttattgat gatgattgat tgatggactc taatcaaatc tggatgcagt
    10981 tgttcaattt ttgataacgt tccataaaat tctcttttaa aatttttacc aaccattgat
    11041 acacgatgat cgtattccgt ttgaaagaaa taaatatcat taatatccat ttttatagaa
    11101 gacgctttta agttaatgat aatatattca ctttttgtct ttatattttc tttttgttga
    11161 atatatgcat cgacacatgt ttcgacctct ttttggaaat ctagaaaatc cacgttcttt
    11221 tgaataaatt gaagagctga aaccatatat ttgtaggaag ttaaaactaa ttctgtgtga
    11281 gtagaaataa atacaatcag actttcactg tctgtttttc tgatttcttt ggcaacctca
    11341 aatcctgcct ggatatgatt gttcatttgg atatctagga aaaagatatt tagttgggcg
    11401 tcctggtgtg ccacttgtaa taattcatct gaacgtgaaa ataaatggat tgtttcatta
    11461 taaatatttc ttgaatgtag gatatttgtt accaatgctt ctaacgcttt tgcttgaata
    11521 atttggtctt ctaatatata aatagccatt tgttcactca tccctttctc aagaagatat
    11581 aaaattacac aacaaaagac aaatgattat aatgttcaat caatttatac accaataaaa
    11641 aagataaaaa attgattgtc tgttagtata ttcacataaa tttagtatag cgatttcagt
    11701 agtttcctgc aaacaaaaac ataaaataac aaagcatcaa gaaagagtac tttggactat
    11761 tcatctttta ctaacgaatc atgaggacta ttgtctcttc gttgatgaaa aacaaagaat
    11821 caaccgccaa actgttcttg tcattttata catgacaaaa tcaattcatt ggttgattct
    11881 ggttatttta atttgttagt tcacacatga atcattgtgc taatttttta cttaaacatc
    11941 cacagttctt cctgttgaat gagtcgatta agcgccaatg taggtcacgc cactactata
    12001 agcaattaca ttaggtaaga cacgatacga aatcgtttga tcattgatga cattgctttc
    12061 agaaataatg attccatcag aagtgaccgc ttcaacaaaa gcaacatgtc catattgatt
    12121 atctgcgcca gcaactcctg gttggaaact aatcgcacga ccagctttag gcaatgaact
    12181 aacttgatag cctaatgcac gtccttttct tccccagtca ctgccatttc ccataaattc
    12241 atccacagaa gtgcccaact gtttgaaacg attatagaca taccacgtac attggcccac
    12301 gggatagcta ccacttcgat tataattgat cccatcatag actggaaaat gcatttgttg
    12361 ctgttccgct tctgacagct catttttaga ttggataatc aaaccgtcca ctgtttttgg
    12421 taaatcaaat tgcgttaagt tataaaccgc aattaacgaa tttaatttat tatcgtattg
    12481 cttgtctgtt gcatatttac ctgttaaaaa acgcgttgct tgaaggtagt ttttggcttc
    12541 cgaacgccac gctggtttat aaaaatcttg atttccgtca atcccttgtc ggagtaattg
    12601 aacataatct tgcagtgagt cattatagcc accgtaatcg cgaaacccag cggaaattgt
    12661 ataaagttgg cccctctgat cagcctcttt tgttgaaaag ctaacactat ttccttggaa
    12721 cgaacctttc acgccaaaga gattataata aggttctttg gctagttgac tttcgccaga
    12781 gccactttct aaaatagcct gagctatcat cactgatgca aaaacatcgt atttttcgcc
    12841 aagttctctg gctgtctcac caattttttt aataaacgct gtggtttgtt ctgacttctg
    12901 catttcaaat gacgcaccat atgttgttaa aacttctttg ccatactccg ttaatgtgaa
    12961 ctccttaaaa ggattagtca ctaccaagcg tttttcctct tttgagtctg gttgttgttt
    13021 ggcagtatag atattctcta actgagcgat tacttctggt ttctctttag aatccgattc
    13081 cgctgcggca attaaatatt ttccttggcc aagataaaca ccattttgaa gcgtttttcc
    13141 ttcagctgtt tgccaaaaaa tcagatcacc aggttctgcc tcctctatag aacgaacttt
    13201 accaaatgtc atttgttctt gcggcgtact gccaatgtct attttaaata attgttggta
    13261 aattttttgg gcaaggaaac tactggtcaa tgcttgctcc gtcaaattaa attctttttt
    13321 tgttttccca acgtgtctta atgcttcagc caccacaact gcccgtttct gttcgtcaaa
    13381 agacgacaac agtggaagtt cgtagccttt taaatttgaa gaagctattt catctacttt
    13441 gagggacgga tttaacgata cagcctgatt ttcttcaaca acgttattgg tggcttcagg
    13501 aacttgaata ggttcttcgg gttcttgctt ggtcacagga acttgtggtg gttgcgattg
    13561 ttcaacaggc tgcgtgattt ctgatgatac cgttgactct gtaggttctt tttttgtttc
    13621 agaactagta tttgtggttg tcgtttctgt cattgactga ctcgttgatt cggtagtcgt
    13681 atcggtagaa ctacttgatt cagatgacga actactagtg gacgttgtcg atgtagcaac
    13741 agttgtttcg gttgtttcgg ttactttttc ttccgaagta attgtcgttg ctgaggacag
    13801 agctgtttgt agtgagctac ttggtaattc tgcagccaac gtaacaactg gagcgacttc
    13861 caaactcaga agaacgagaa tacttgttaa aacaagtagt tgattcttga ttttctttct
    13921 tttcattcgt aaaaatcctc tcctattact tacttgcgca tttgcacact gtttttgtac
    13981 aaatgcgcct tgtaagttaa tgatacgcta attttggtct tttttatttt tgaagaataa
    14041 ttttcctaaa ccaatactta ctatcaatag aaaaccactg attgaccaga ttggcgaaac
    14101 aacttcattt gcttttggca aagtaccaga agtagtggtt ttcgttgtcg ttccacctgt
    14161 tgttgtgccc tttcctggac tggttacgcc accagtcccg ctaaccgtgc catgatttcc
    14221 attgttgcct gtagagttgc tactgattgg ctcttctgcc attgcttcaa tggcttgtgc
    14281 taaaatactt aaacatttgt ccacagcttc ttgcgtcgca tttgggtcct caacaagtgc
    14341 ttttgcttgt ttaattgctt cagctaaagc ttcttgcgat gcttttgtaa attgttttcc
    14401 tgctttaggt ttcaaggttt ctgctttttg aagcagttct ttcaactttg ttttatccgt
    14461 ttgaaggact tgttcctcta aactatccaa agcagttttt acattttttt cagcaatatc
    14521 aatttggtct tgccgagcat ttttatcagc taaaatccct tccgcttggt caattgcttc
    14581 agttaaacgc gctttagact cgctggtaaa ttcttttcca gcagatggtt tgattgcttt
    14641 tgctttggct atcattgcct ctaaggcttt tttatctgta actaacgctt cttcttgtaa
    14701 cccttcgatg gcgctagtta attcagcaac cgcttcatca atcatttttt gattagctgc
    14761 tgggttttcc aatgtgtttt tagctgctaa aagcactttt tgtaaatctt gtaacgagga
    14821 ggcagtaaat tggtgccctt cacttggagt gacttgctgc gctcgtttga ctacttcttg
    14881 taattggtct ttatttacaa ggggtacttc ttttaattga gccattgcag tttccaatgc
    14941 gtttagagcc tctgagactt cttcttttgt cgccgtttct ttcgctacga ttgcttcagc
    15001 tgcttgaatt gcttcttgca attgtttttc tgtttctttt gtaaattggt atccttcttc
    15061 cggctttctt cctcgggctt gagcgatttt ctcttttaag gtttccttat caacggcgac
    15121 gggttgttct tttaattgtg caattgcttc acgcaatgtt ttagtcgctt ggtctatttc
    15181 ttcttgggta actttttctt gagcaaatac tttttgagct gctgctaatg actcttcgag
    15241 aactttttta gtttcttcgg tgaattcttg cccatcactt ggtttctttg ttagcccctc
    15301 ttgaattgct ttttctaaat cagctttatt cgctacatca ggcatttttt ccaactgttc
    15361 tacagccttt tctagatttt ccacagcagc agaaacgtct gtctgtgtgg cttgctcatt
    15421 ggctagaaca gctactgcct catctaagat tggtttaaag attgcccaag tttcaggtgt
    15481 atattctttt tcgacacgtg cttgatttag cgtaattagc gcttgtaata actctttatc
    15541 tactagctct gttggcttca ctgttacaga aaaatctgaa agtgtggctt gttggaatcc
    15601 ttggcccact aataagcctt gactcatatc aaattgtaat gactgctcaa cagttgtcgc
    15661 acgttttacg cgagttgttt cttttacttt aactttaaag gtaactaagt ccattgaacc
    15721 gtttaacaat tgtttatttc cttgattact aagaactaaa tatagattct ccacatcatt
    15781 tgaatgtttc cgatatttag aataattttc catttgtttt gtattattcg tggttgcagg
    15841 ctgaccgaca agttcaaatt tgctagaatc aaaggacatt tttgtgctta acgcattaat
    15901 gttttttaag tcttgacctt taagtgtaaa ggttaatgta tcgccaggaa gataggtatc
    15961 cttgccattt tcattaacca cagcaaggga taaaccgccc gcaatttctt cgacatcagg
    16021 tatctcaatc ccgccatcta attgtcgtaa aacataactg atatcataag catcaattaa
    16081 cccattttta tttaaatcac ctttttcaac atagccatta aaatcactgt ccaccgattc
    16141 taagcctgta tagtttcgat aactcattgc atcattttca tcaatcgttc catcgttagt
    16201 aatgtctcca tgtaagattc cttctgttcc tggttgtttg taaaagagca tctcacgacc
    16261 agagccaaaa ttacccaccg attttaatac ctttatttca acaaaacgat acgcttggtc
    16321 cttcgtttca atggtttttg tcaaagcatc ttgcttccag ttaataggtt ctgaaaactc
    16381 tgtccaatta gctccatctt tcgacgtccg atactggagc tgcaaaatat ttccgttgcc
    16441 ggcattgtct cttggcaagt attcaatttt atccatttga tactccgcac caagatcaaa
    16501 ttttaaagtc aagaaatttc catcacttgg attagcgatg ccggttgacc agttcgtatg
    16561 ccaacctgta cttaaatctt tatctgttaa tttcttcaat tctgcgcctg gttgttctgg
    16621 taaattactt gttgctttga cttgattaat tgtttcttta tagggatcat cttgtgtttt
    16681 ccctttaatt ggttcactcc attcagaaac cccatttttt ccaacagctc gaactcgaaa
    16741 agtatgttcg cttaggaagg aaaatccatc aaatgttgct gtattcgttt gaatatttcc
    16801 aaaaacagtc ccgtcacgct ctacttcata acttgttgcc tcagttactt gatcccattg
    16861 aagagtcaaa gaagatggcg ttgttttttc ttcattgatt gcgacatttg ccggaatagt
    16921 taactggtca tcgaccgttg tatttcctcc atcaaccgtt cctttattaa tgaaaccttt
    16981 gacagttatt tgaacatctt tggcggtcac agattgtttc gctagtttta ctgataacgc
    17041 tgattggttc agtttttctc ctgaagcttc agaaagatac tgattcactt ggaattcttt
    17101 atcaaaataa tatagatttg tgccagctaa aaattcttct ttattagctg cttgtttcaa
    17161 ggttacttct gttcccccca ccattgctgt tacgctttcg ggcgcttctg aagctagcaa
    17221 atcaagcgtg gtgcttcgtt catcaacaaa gtctttataa cttccttttg tcggttcgat
    17281 agtaacggtc agatcccctt tttcgtttga tttagggcct tgactattta ttttagtcgt
    17341 agctgattgc ccagcttcat aactagttga aattccgtca tcttcataca tattaaaaga
    17401 agtggtgcca tttggataaa tcaagaaaga tcgttgatct cgttggattt cctttggatt
    17461 gttgtttgga ttcgtcattg ggataatact gccatctttg acgaaaacgg gcaccttcca
    17521 cagcggtgtt tttactccat ttaagacacg gccaccttga tatttttcgc ctgtaaataa
    17581 gtcaacccag acttgttttt catctggtaa gtagattcca tcacggattg aatttcctgc
    17641 ctcatcttga ttgccattat aaattggggc aacgagtaaa ttgggtcccc acatatattg
    17701 gtattgagaa tcttttgtat atgctgttcc ttcattagga aattctaaag ccatggcccg
    17761 taccattggt agtccatcaa ctgattcctt ggcaatactg tagttataag gcatcatcat
    17821 tgattttaat tttagatacg ctcggttcaa atctgtggct tcttgatcaa aagcaaatgg
    17881 cgttttcgga ttggagcccc agccgtccat atttagctgc actggtgtaa aagttttcca
    17941 ttggaaatca cgtatgttga cctctttatt ttttccacca aaaattccat ccatatctga
    18001 accaacattt ggttggccag acaacgaagt cccgatatat gttgggatat ggaagcgaat
    18061 atattcccat tgaccacccg tttgatcgcc tgtccaaata ccagcgtgcc gttgggttcc
    18121 ggcccaacca tctaatgaga caatcatcgg acgaactgcg ccgtctgttt cttttacaaa
    18181 aacatttgca gcatcttcta caccatttaa gccaaaggaa tacccatacc cgacccacgc
    18241 cacgtcagtt ttgagggctt taacaccagc gacactaact tctttcgcaa tatcccgttc
    18301 tcctttttta ggatttttag gatcagctgg atggagatta gattgagtcc acagccccac
    18361 ttcaacacca ttggcttgag cataatcagt aaattctttt aagttttgta catcgccatc
    18421 caatgaatct gtttgaccat agccagcacc gtagccgtca tttggcaaga accaccctaa
    18481 tggcatatcg tttttcttat accgatcaat aactgcgcgt gcagaaaatt gataattctc
    18541 tttttctcca tttaaagatt ctagcgtgcc atttaagttt cctagatcgc ctggttggta
    18601 ttctttgtaa aaattaccat cttcaaactt aactgctccc gcggttcctt ctgctacttt
    18661 cacccaatag tcccgattat acgcgtttaa atgcgcttca tagaacccgt attctggcat
    18721 caaagctggt ttcccggtta attcatagta atcttttaaa atacctgctg aggaatcatt
    18781 aaagaaataa aaggcatcaa aatctgttcc ttcgtgcgtt gttgtggttg tttgtggatc
    18841 atgacttcca aaatcatagt tgccaggttt ccatgtattt cgaacaacgc cataccctgc
    18901 agttgaccaa taaaatgggt taggcgatgc tactccgcca tctacccaat tgttcgtatt
    18961 gacaatctgg atagctgttc ctttgtgcgt aaatcgacca ttttgagttc ctccgccaaa
    19021 ataattttct tgactacttt gttttaacgt ttgtgtagct ttatcatttt taaaggatag
    19081 cggagcggtt tcttctaaaa tgacttgatc ctttttcttg tctagaacct tcattaaagc
    19141 gctttctttt tcgaatataa tttttaaacc attattttct agagtaaatt ggtttcctga
    19201 atctgtgacg ttcgtttgct caaaggcttg tgtgccatag tcggccattg ttttagccgt
    19261 aattttcgca acatgctttg gatcatttgg cgttggatat tcttcaaatt taccagttgg
    19321 atctagatga tagcgaaaaa gatggtcgtt taaaatacta atttgtgctt tttttccaga
    19381 agcatacgta atgacaaagt ttttctccgc tttttcaatc gacacaattg ctccgactga
    19441 cgttgctgaa tcagctacgt cttcttttgc tgtttgctct tgcgcatcaa ccacttgaga
    19501 atccatcgta acaaacgaat ggaacgccaa tacagacgaa ctcactaata aaaatgtcaa
    19561 ccagtgcttt ttaccgtaaa tttttttacc ctgatactct ttgttcattt tttcctcctt
    19621 aaaattgctc cccatagaat agttccgaca caattactca caaaatccaa aacccaacaa
    19681 agttttatcc agatgaaaag tcataacgat tttcttagtt tactgagact gtaagcaagt
    19741 cagtttcagt aaacccttcc taaacacatc ctttcaataa aatattaaat gaaaacaatc
    19801 tattttcatc ttatataaaa attttagtac agaatcacaa tttcctgatg aatgcacttt
    19861 catttattga ctaccaattt ttcacttttt taataacata attatcgtat gatggttttt
    19921 ttgtgtttgt caacggttaa ttatagcagc caccattaac gagtattaac ccttgataaa
    19981 cctgttaatt cacttataat gatgatttta ttgcgaaaat atccacatca gaaaaagaaa
    20041 gacttttttc aaaaatctaa tacctgttgc tcaaatttag tctatttaaa aatattaaac
    20101 accctcctgc tcagcaagag ggtgttgatt actcgttttt tagtgattga tttgacttgc
    20161 tggtgtgaaa agcaaactaa tgatgatgcc aactatcagt accgctagca atataaaaat
    20221 taactttcca aaccggtgat agggattgat cgaaagccca atcccataaa ctttcggaac
    20281 ccacaaagga ggcgttggat tatctttttg atctttatag gctatcttta aaatctgcca
    20341 cgcaaaatac aacaatggta aaaccataat taccccaact atacctagcc attttgctaa
    20401 taagtcacta gtatgcaaaa gactgattgt cagaattggt acaaacaaaa gaataaagct
    20461 aattgtggct cccacttgtg cttgcttaag cagtcgtctc tcacggagag taagattcgc
    20521 aaacattcca tccatccttt catggttttc agattaaatc aatgaatcac taaaaaacta
    20581 aattaactgc gaaaatcaat gaccattcgc ccgcgaattt tcccttgttc catttcttca
    20641 aaaatagcat taatttcttc tggttggcgt gtttgacaaa caggaacaac ttttccttct
    20701 gcaccgaatt ggaaagcttc gcttaaatc
//
