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Overview
1.1
1.2
1.3

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_LR607361.1 (Enterococcus faecalis)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1 | lanthipeptide-class-ii | 1,042,367 | 1,070,214 | Low | staphylococcin C55 α/staphylococcin C55 β | ribosomal:RiPP:Lanthipeptide
Region 2 | cyclic-lactone-autoinducer | 1,777,291 | 1,798,019 |
Region 3 | terpene-precursor | 2,702,949 | 2,723,830 |

NZ_LR607361.1 - Region 1 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 1,042,367 - 1,070,214 nt. (total: 27,848 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
FN738_RS03760: crotonyl-CoA reductase / alcohol dehydrogenase

smcogs
  SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase

Lyases: cyclase
FN738_RS03745: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

FN738_RS03755: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000520.5 |  | 0.78 | ribosomal | lacticin 3147 A1, lacticin 3147 A2 | Lactococcus lactis
BGC0000555.3 |  | 0.70 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0001229.4 |  | 0.63 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0002110.3 |  | 0.59 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0001391.3 |  | 0.55 | ribosomal | thusin | Bacillus thuringiensis serovar rongseni
BGC0000525.5 |  | 0.53 | ribosomal | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0000517.4 |  | 0.51 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0001555.4 |  | 0.51 | ribosomal | colicin V | Escherichia coli chi7122
BGC0001210.5 |  | 0.51 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0002663.2 |  | 0.51 | ribosomal | amyloliquecidin GF610 | Bacillus amyloliquefaciens UMAF6639

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000520.5 |  | 0.78 | ribosomal | lacticin 3147 A1, lacticin 3147 A2 | Lactococcus lactis
BGC0000555.3 |  | 0.70 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0001229.4 |  | 0.63 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0002110.3 |  | 0.59 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0001391.3 |  | 0.55 | ribosomal | thusin | Bacillus thuringiensis serovar rongseni
BGC0000525.5 |  | 0.53 | ribosomal | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0000517.4 |  | 0.51 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0001555.4 |  | 0.51 | ribosomal | colicin V | Escherichia coli chi7122
BGC0001210.5 |  | 0.51 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0002663.2 |  | 0.51 | ribosomal | amyloliquecidin GF610 | Bacillus amyloliquefaciens UMAF6639

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for FN738_RS03745

FN738_RS03735
Leader:
MRDEENNETLINNEQVAWFEEVADQSFDDDVFGA
Core:
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
Core with dehydrations:
CysDhbDhbNDhbFDhaLDhaDYWGNKGNWCysDhbADhbHECysMGWCysK

#### antiSMASH-DB 4.0 matches for FN738_RS03735

100.0%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06515_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide
Lanthipeptides: PO853_RS06515_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
93.3%
NZ_BLIS01000009.1 and 7 others:
NZ_BLIS01000009.1 Lanthipeptides: GVO03_RS04820_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide
Lanthipeptides: GVO03_RS04820_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
CTTNTFSLSDYWGNKGNWCT THECM WCK
1
CTTNTFSLSDYWGNKGNWCTLTHECMNWCK
30
93.3%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06330_lanthipeptide
Lanthipeptides: IE339_RS06330_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
CTTNTFSLSDYWGNKG WCTATHECM WCK
1
CTTNTFSLSDYWGNKGGWCTATHECMSWCK
30
with 105 more sequence matches
Only the first 10 are displayed here.
93.3%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09620_lanthipeptide
Lanthipeptides: CQS04_RS09620_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
CTTNTFSLSDYWGN GNWCTATHECM WCK
1
CTTNTFSLSDYWGNNGNWCTATHECMSWCK
30
86.7%
NZ_FMPI01000012.1 and 1 other:
NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08305_lanthipeptide
Lanthipeptides: BJR39_RS08305_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDYWGN GNWCTA+HECM WCK
1
CSTNTFSLSDYWGNNGNWCTASHECMSWCK
30
86.7%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23160_lanthipeptide
Lanthipeptides: CN977_RS23160_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
CTTNTFSLSDYWGN G+WCTATHEC+ WCK
1
CTTNTFSLSDYWGNDGSWCTATHECLSWCK
30
83.3%
NZ_CACZYW010000004.1 and 1 other:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide
Lanthipeptides: HUF10_RS02825_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDYWGN GNWCT +HECM WCK
1
CSTNTFSLSDYWGNNGNWCTLSHECMAWCK
30
83.3%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide
Lanthipeptides: allorf_0097945_0098112_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDYWGN+G WCT THECM WCK
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
83.3%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18440_lanthipeptide
Lanthipeptides: EI692_RS18440_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDYWGNKG WCT +HECM WCK
1
CSTNTFSLSDYWGNKGGWCTISHECMSWCK
30
83.3%
NZ_QGEE01000020.1 and 5 others:
NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06160_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide
Lanthipeptides: DKP74_RS06160_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDYWGN+GNWCT +HECM WCK
1
CSTNTFSLSDYWGNRGNWCTLSHECMAWCK
30
80.0%
NZ_CP016767.1 and 11 others:
NZ_CP016767.1 Lanthipeptides: BCV50_RS13410_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15325_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15325_lanthipeptide NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07920_lanthipeptide NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07920_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00580_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00580_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17015_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17015_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04645_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04645_lanthipeptide
Lanthipeptides: BCV50_RS13410_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWC
29
CTTNTFSLSDYWGNKG WCT + ECM WC
1
CTTNTFSLSDYWGNKGGWCTVSKECMAWC
29
80.0%
NZ_CP051884.1 and 2 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide
Lanthipeptides: HGK68_RS15125_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDYWGN G CT THECM WCK
1
CSTNTFSLSDYWGNNGWLCTITHECMSWCK
30
80.0%
NZ_FNHR01000005.1 and 1 other:
NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05590_lanthipeptide
Lanthipeptides: BLQ37_RS05590_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDY GN GNWCT +HECM WCK
1
CSTNTFSLSDYMGNNGNWCTISHECMAWCK
30

#### MIBiG 4.0 matches for FN738_RS03735

63.3%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWC
29
CTTNTFSLS+ GN G WCT T EC C
1
CTTNTFSLSNALGNNGGWCTLTKECQPNC
29
40.0%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
6
FSLSDYWGNKGNWCTATHECMGWC
29
+++S GNKG +CT T ECM C
4
YNISCRLGNKGAYCTLTVECMPSC
27
12.8%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
CTATHECMGWC
29
CT + EC C
28
CTLSKECQPNC
38
FN738_RS03740
Leader:
MNNDKQNEQNVDLELGKYLEADLISLTDDEVTGG
Core:
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
Core with dehydrations:
GDhbPDhbIDhbIPIDhaIAVDhaGWIDhaDKDhbCysPDhbDhaVCysDhbRACys

#### antiSMASH-DB 4.0 matches for FN738_RS03740

100.0%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide
Lanthipeptides: PO853_RS06520_lanthipeptide
1
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
31
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
1
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
31
61.3%
NZ_CP051884.1 and 3 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide
Lanthipeptides: HGK68_RS15130_lanthipeptide
1
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
31
GTPT+ + I VS WIS+ TCP+S CTRAC
1
GTPTVVLSI---VSAWISNNTCPSSACTRAC
28
61.3%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide
Lanthipeptides: IE339_RS06335_lanthipeptide
2
TPTITIPISIAVSGWISDKTCPTSVCTRAC
31
TPTI I AV+G+IS TCPT+ CTRAC
2
TPTIVI---TAVTGYISTNTCPTTSCTRAC
28
with 77 more sequence matches
Only the first 10 are displayed here.
61.3%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23165_lanthipeptide
Lanthipeptides: CN977_RS23165_lanthipeptide
2
TPTITIPISIAVSGWISDKTCPTSVCTRAC
31
TPT++I ++ AVSG+IS TCPT+ CTRAC
2
TPTVSIALT-AVSGYISSNTCPTTACTRAC
30
54.8%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: C3B71_RS16030_lanthipeptide
Lanthipeptides: C3B71_RS16030_lanthipeptide
2
TPTITIPISIAVSGWISDKTCPTSVCTRAC
31
TP + +AV G+IS TCPT+VCTRAC
2
TPAVATAALLAVGGFISHNTCPTTVCTRAC
31
54.8%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide
Lanthipeptides: EI692_RS18435_lanthipeptide
5
ITIPISIAVSGWISDKTCPTSVCTRAC
31
+T ISI VSG+IS TCP++ CTRAC
1
VTPAISILVSGFISTNTCPSTACTRAC
27
54.8%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide
Lanthipeptides: CQS04_RS09625_lanthipeptide
1
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
31
TPTI I A++G+IS +CPT+ CTRAC
1
ATPTIVI---TAITGYISANSCPTTACTRAC
28
50.0%
NZ_CACZYW010000004.1 and 3 others:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide
Lanthipeptides: HUF10_RS02820_lanthipeptide
8
PISIAVSGWISDKTCPTSVCTRAC
31
P+ +AVS ++SDKTCPT+ CTRAC
9
PVIVAVSAYVSDKTCPTTACTRAC
32
48.4%
NZ_KE384533.1 and 2 others:
NZ_KE384533.1 Lanthipeptides: K329_RS31315_lanthipeptide NZ_KE384533.1 Lanthipeptides: K329_RS31315_lanthipeptide
Lanthipeptides: K329_RS31315_lanthipeptide
2
TPTITIPISIAVSGWISDKTCPTSVCTRAC
31
TPTI I + VS ++S TCPT+ CT C
1
TPTIVISV---VSAYVSTNTCPTTSCTDEC
27
42.4%
NZ_LR134317.1 and 1 other:
NZ_LR134317.1 Lanthipeptides: EL136_RS01690_lanthipeptide
Lanthipeptides: EL136_RS01690_lanthipeptide
7
IPISIAVSGWISDKTCPTSVCTRAC
31
+ S+AV+ +IS TCPT+ CTRAC
9
VKASVAVTAFISANTCPTTSCTRAC
33
42.4%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide
Lanthipeptides: BHL26_RS15355_lanthipeptide
12
AVSGWISDKTCPTSVCTRAC
31
AVSG+IS TCP++ CTRAC
14
AVSGYISSNTCPSTACTRAC
33
41.9%
NZ_CP016767.1 and 3 others:
NZ_CP016767.1 Lanthipeptides: BCV50_RS13415_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide
Lanthipeptides: BCV50_RS13415_lanthipeptide
8
PISIAVSGWISDKTCPTSVCTRAC
31
P ++G+IS TCPT+ CTRAC
3
PALSVITGYISSNTCPTTACTRAC
26
41.9%
NZ_CP050134.2 and 3 others:
NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS14310_lanthipeptide NZ_LR134504.1 Lanthipeptides: EL293_RS13085_lanthipeptide NZ_LR134504.1 Lanthipeptides: EL293_RS13085_lanthipeptide
Lanthipeptides: HBA49_RS00775_lanthipeptide
3
PTITIPISIAVSGWISDKTCPTSVCTRAC
31
P+ IPISIA+ CPT+ C+R C
3
PSTLIPISIAL--------CPTTRCSRRC
23

#### MIBiG 4.0 matches for FN738_RS03740

24.3%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
7
IPISIAVSGWISDKTCPTSVCTRAC
31
+ I V+ +S CPT+ CT C
13
VAIQAGVAVGVSAAFCPTTKCTSRC
37
19.4%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
22
CPTSVCTRAC
31
CPT+ CT C
17
CPTTKCTSKC
26
allorf_1048534_1048659
Leader:
MVAQLVEQRIEAPCVGSSTLSHAIYGG
Core:
IAKWLNATDCKSVP
Core with dehydrations:
IAKWLNADhbDCysKDhaVP

#### antiSMASH-DB 4.0 matches for allorf_1048534_1048659

100.0%
NZ_AP026714.1 and 15 others:
NZ_AP026714.1 Lanthipeptides: allorf_1211804_1211929_lanthipeptide NZ_CP028724.1 Lanthipeptides: allorf_2251561_2251686_lanthipeptide NZ_CP092907.1 Lanthipeptides: allorf_0820552_0820677_lanthipeptide NZ_KB944759.1 Lanthipeptides: allorf_0005263_0005388_lanthipeptide NZ_KZ845892.1 Lanthipeptides: allorf_0004017_0004142_lanthipeptide NZ_KZ845958.1 Lanthipeptides: allorf_1540463_1540588_lanthipeptide NZ_KZ845958.1 Lanthipeptides: allorf_1540463_1540588_lanthipeptide NZ_LR607361.1 Lanthipeptides: allorf_1048534_1048659_lanthipeptide NZ_LR607361.1 Lanthipeptides: allorf_1048534_1048659_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: allorf_347989_348114_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: allorf_347989_348114_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_003528_003653_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_003528_003653_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1655405_1655530_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1655405_1655530_lanthipeptide
Lanthipeptides: allorf_1211804_1211929_lanthipeptide
1
IAKWLNATDCKSVP
14
IAKWLNATDCKSVP
1
IAKWLNATDCKSVP
14

#### Lanthipeptide(s) for FN738_RS03755

FN738_RS03735
Leader:
MRDEENNETLINNEQVAWFEEVADQSFDDDVFGA
Core:
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
Core with dehydrations:
CysDhbDhbNDhbFDhaLDhaDYWGNKGNWCysDhbADhbHECysMGWCysK

#### antiSMASH-DB 4.0 matches for FN738_RS03735

100.0%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06515_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide
Lanthipeptides: PO853_RS06515_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
93.3%
NZ_BLIS01000009.1 and 7 others:
NZ_BLIS01000009.1 Lanthipeptides: GVO03_RS04820_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide
Lanthipeptides: GVO03_RS04820_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
CTTNTFSLSDYWGNKGNWCT THECM WCK
1
CTTNTFSLSDYWGNKGNWCTLTHECMNWCK
30
93.3%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06330_lanthipeptide
Lanthipeptides: IE339_RS06330_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
CTTNTFSLSDYWGNKG WCTATHECM WCK
1
CTTNTFSLSDYWGNKGGWCTATHECMSWCK
30
with 105 more sequence matches
Only the first 10 are displayed here.
93.3%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09620_lanthipeptide
Lanthipeptides: CQS04_RS09620_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
CTTNTFSLSDYWGN GNWCTATHECM WCK
1
CTTNTFSLSDYWGNNGNWCTATHECMSWCK
30
86.7%
NZ_FMPI01000012.1 and 1 other:
NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08305_lanthipeptide
Lanthipeptides: BJR39_RS08305_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDYWGN GNWCTA+HECM WCK
1
CSTNTFSLSDYWGNNGNWCTASHECMSWCK
30
86.7%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23160_lanthipeptide
Lanthipeptides: CN977_RS23160_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
CTTNTFSLSDYWGN G+WCTATHEC+ WCK
1
CTTNTFSLSDYWGNDGSWCTATHECLSWCK
30
83.3%
NZ_CACZYW010000004.1 and 1 other:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide
Lanthipeptides: HUF10_RS02825_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDYWGN GNWCT +HECM WCK
1
CSTNTFSLSDYWGNNGNWCTLSHECMAWCK
30
83.3%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide
Lanthipeptides: allorf_0097945_0098112_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDYWGN+G WCT THECM WCK
1
CSTNTFSLSDYWGNRGYWCTLTHECMSWCK
30
83.3%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18440_lanthipeptide
Lanthipeptides: EI692_RS18440_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDYWGNKG WCT +HECM WCK
1
CSTNTFSLSDYWGNKGGWCTISHECMSWCK
30
83.3%
NZ_QGEE01000020.1 and 5 others:
NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06160_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide
Lanthipeptides: DKP74_RS06160_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDYWGN+GNWCT +HECM WCK
1
CSTNTFSLSDYWGNRGNWCTLSHECMAWCK
30
80.0%
NZ_CP016767.1 and 11 others:
NZ_CP016767.1 Lanthipeptides: BCV50_RS13410_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15325_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15325_lanthipeptide NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07920_lanthipeptide NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07920_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00580_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00580_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17015_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17015_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04645_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04645_lanthipeptide
Lanthipeptides: BCV50_RS13410_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWC
29
CTTNTFSLSDYWGNKG WCT + ECM WC
1
CTTNTFSLSDYWGNKGGWCTVSKECMAWC
29
80.0%
NZ_CP051884.1 and 2 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide
Lanthipeptides: HGK68_RS15125_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDYWGN G CT THECM WCK
1
CSTNTFSLSDYWGNNGWLCTITHECMSWCK
30
80.0%
NZ_FNHR01000005.1 and 1 other:
NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05590_lanthipeptide
Lanthipeptides: BLQ37_RS05590_lanthipeptide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWCK
30
C+TNTFSLSDY GN GNWCT +HECM WCK
1
CSTNTFSLSDYMGNNGNWCTISHECMAWCK
30

#### MIBiG 4.0 matches for FN738_RS03735

63.3%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
1
CTTNTFSLSDYWGNKGNWCTATHECMGWC
29
CTTNTFSLS+ GN G WCT T EC C
1
CTTNTFSLSNALGNNGGWCTLTKECQPNC
29
40.0%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
6
FSLSDYWGNKGNWCTATHECMGWC
29
+++S GNKG +CT T ECM C
4
YNISCRLGNKGAYCTLTVECMPSC
27
12.8%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
CTATHECMGWC
29
CT + EC C
28
CTLSKECQPNC
38
FN738_RS03740
Leader:
MNNDKQNEQNVDLELGKYLEADLISLTDDEVTGG
Core:
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
Core with dehydrations:
GDhbPDhbIDhbIPIDhaIAVDhaGWIDhaDKDhbCysPDhbDhaVCysDhbRACys

#### antiSMASH-DB 4.0 matches for FN738_RS03740

100.0%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide
Lanthipeptides: PO853_RS06520_lanthipeptide
1
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
31
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
1
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
31
61.3%
NZ_CP051884.1 and 3 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide
Lanthipeptides: HGK68_RS15130_lanthipeptide
1
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
31
GTPT+ + I VS WIS+ TCP+S CTRAC
1
GTPTVVLSI---VSAWISNNTCPSSACTRAC
28
61.3%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide
Lanthipeptides: IE339_RS06335_lanthipeptide
2
TPTITIPISIAVSGWISDKTCPTSVCTRAC
31
TPTI I AV+G+IS TCPT+ CTRAC
2
TPTIVI---TAVTGYISTNTCPTTSCTRAC
28
with 77 more sequence matches
Only the first 10 are displayed here.
61.3%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23165_lanthipeptide
Lanthipeptides: CN977_RS23165_lanthipeptide
2
TPTITIPISIAVSGWISDKTCPTSVCTRAC
31
TPT++I ++ AVSG+IS TCPT+ CTRAC
2
TPTVSIALT-AVSGYISSNTCPTTACTRAC
30
54.8%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: C3B71_RS16030_lanthipeptide
Lanthipeptides: C3B71_RS16030_lanthipeptide
2
TPTITIPISIAVSGWISDKTCPTSVCTRAC
31
TP + +AV G+IS TCPT+VCTRAC
2
TPAVATAALLAVGGFISHNTCPTTVCTRAC
31
54.8%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide
Lanthipeptides: EI692_RS18435_lanthipeptide
5
ITIPISIAVSGWISDKTCPTSVCTRAC
31
+T ISI VSG+IS TCP++ CTRAC
1
VTPAISILVSGFISTNTCPSTACTRAC
27
54.8%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide
Lanthipeptides: CQS04_RS09625_lanthipeptide
1
GTPTITIPISIAVSGWISDKTCPTSVCTRAC
31
TPTI I A++G+IS +CPT+ CTRAC
1
ATPTIVI---TAITGYISANSCPTTACTRAC
28
50.0%
NZ_CACZYW010000004.1 and 3 others:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide
Lanthipeptides: HUF10_RS02820_lanthipeptide
8
PISIAVSGWISDKTCPTSVCTRAC
31
P+ +AVS ++SDKTCPT+ CTRAC
9
PVIVAVSAYVSDKTCPTTACTRAC
32
48.4%
NZ_KE384533.1 and 2 others:
NZ_KE384533.1 Lanthipeptides: K329_RS31315_lanthipeptide NZ_KE384533.1 Lanthipeptides: K329_RS31315_lanthipeptide
Lanthipeptides: K329_RS31315_lanthipeptide
2
TPTITIPISIAVSGWISDKTCPTSVCTRAC
31
TPTI I + VS ++S TCPT+ CT C
1
TPTIVISV---VSAYVSTNTCPTTSCTDEC
27
42.4%
NZ_LR134317.1 and 1 other:
NZ_LR134317.1 Lanthipeptides: EL136_RS01690_lanthipeptide
Lanthipeptides: EL136_RS01690_lanthipeptide
7
IPISIAVSGWISDKTCPTSVCTRAC
31
+ S+AV+ +IS TCPT+ CTRAC
9
VKASVAVTAFISANTCPTTSCTRAC
33
42.4%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide
Lanthipeptides: BHL26_RS15355_lanthipeptide
12
AVSGWISDKTCPTSVCTRAC
31
AVSG+IS TCP++ CTRAC
14
AVSGYISSNTCPSTACTRAC
33
41.9%
NZ_CP016767.1 and 3 others:
NZ_CP016767.1 Lanthipeptides: BCV50_RS13415_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide
Lanthipeptides: BCV50_RS13415_lanthipeptide
8
PISIAVSGWISDKTCPTSVCTRAC
31
P ++G+IS TCPT+ CTRAC
3
PALSVITGYISSNTCPTTACTRAC
26
41.9%
NZ_CP050134.2 and 3 others:
NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS14310_lanthipeptide NZ_LR134504.1 Lanthipeptides: EL293_RS13085_lanthipeptide NZ_LR134504.1 Lanthipeptides: EL293_RS13085_lanthipeptide
Lanthipeptides: HBA49_RS00775_lanthipeptide
3
PTITIPISIAVSGWISDKTCPTSVCTRAC
31
P+ IPISIA+ CPT+ C+R C
3
PSTLIPISIAL--------CPTTRCSRRC
23

#### MIBiG 4.0 matches for FN738_RS03740

24.3%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
7
IPISIAVSGWISDKTCPTSVCTRAC
31
+ I V+ +S CPT+ CT C
13
VAIQAGVAVGVSAAFCPTTKCTSRC
37
19.4%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
22
CPTSVCTRAC
31
CPT+ CT C
17
CPTTKCTSKC
26
allorf_1048534_1048659
Leader:
MVAQLVEQRIEAPCVGSSTLSHAIYGG
Core:
IAKWLNATDCKSVP
Core with dehydrations:
IAKWLNADhbDCysKDhaVP

#### antiSMASH-DB 4.0 matches for allorf_1048534_1048659

100.0%
NZ_AP026714.1 and 15 others:
NZ_AP026714.1 Lanthipeptides: allorf_1211804_1211929_lanthipeptide NZ_CP028724.1 Lanthipeptides: allorf_2251561_2251686_lanthipeptide NZ_CP092907.1 Lanthipeptides: allorf_0820552_0820677_lanthipeptide NZ_KB944759.1 Lanthipeptides: allorf_0005263_0005388_lanthipeptide NZ_KZ845892.1 Lanthipeptides: allorf_0004017_0004142_lanthipeptide NZ_KZ845958.1 Lanthipeptides: allorf_1540463_1540588_lanthipeptide NZ_KZ845958.1 Lanthipeptides: allorf_1540463_1540588_lanthipeptide NZ_LR607361.1 Lanthipeptides: allorf_1048534_1048659_lanthipeptide NZ_LR607361.1 Lanthipeptides: allorf_1048534_1048659_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: allorf_347989_348114_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: allorf_347989_348114_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_003528_003653_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_003528_003653_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1655405_1655530_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1655405_1655530_lanthipeptide
Lanthipeptides: allorf_1211804_1211929_lanthipeptide
1
IAKWLNATDCKSVP
14
IAKWLNATDCKSVP
1
IAKWLNATDCKSVP
14

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 28.19 out of 30.25
Confidence: strong
Additional weak hits (4):
DosR
Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 19.89 out of 29.51
Confidence: weak
OsdR
Description: Development and stress management regulator
Species: Streptomyces coelicolor
Score: 16.52 out of 30.12
Confidence: weak
DmdR1
Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 25.25 out of 36.53
Confidence: weak
DmdR1
Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 21.87 out of 36.53
Confidence: weak
Lanthipeptides
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

FN738_RS03735 - Class II
  Cleavage pHMM score: 2.00
  RODEO score: 0
  Monoisotopic mass: 3317.4 Da
  Molecular weight: 3319.7 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3337.7 Da N = 1
    3355.7 Da N = 2
    3373.7 Da N = 3
FN738_RS03740 - Class II
  Cleavage pHMM score: -1.70
  RODEO score: 0
  Monoisotopic mass: 2997.6 Da
  Molecular weight: 2999.5 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3017.5 Da N = 1
    3035.5 Da N = 2
    3053.5 Da N = 3
    3071.6 Da N = 4
    3089.6 Da N = 5
    3107.6 Da N = 6
    3125.6 Da N = 7
allorf_1048534_1048659 - Class II
  Cleavage pHMM score: -3.90
  RODEO score: 0
  Monoisotopic mass: 1508.8 Da
  Molecular weight: 1509.8 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1527.8 Da N = 1
FN738_RS03735 - Class II
  Cleavage pHMM score: 2.00
  RODEO score: 0
  Monoisotopic mass: 3317.4 Da
  Molecular weight: 3319.7 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3337.7 Da N = 1
    3355.7 Da N = 2
    3373.7 Da N = 3
FN738_RS03740 - Class II
  Cleavage pHMM score: -1.70
  RODEO score: 0
  Monoisotopic mass: 2997.6 Da
  Molecular weight: 2999.5 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3017.5 Da N = 1
    3035.5 Da N = 2
    3053.5 Da N = 3
    3071.6 Da N = 4
    3089.6 Da N = 5
    3107.6 Da N = 6
    3125.6 Da N = 7
allorf_1048534_1048659 - Class II
  Cleavage pHMM score: -3.90
  RODEO score: 0
  Monoisotopic mass: 1508.8 Da
  Molecular weight: 1509.8 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1527.8 Da N = 1

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
ColR | Phenol-responsive regulator

NZ_LR607361.1 - Region 2 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,777,291 - 1,798,019 nt. (total: 20,729 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
No tailoring functions detected.
Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001291.3 |  | 0.41 | ribosomal | enterocin NKR-5-3B | Enterococcus faecium
BGC0001948.3 |  | 0.37 | other (other) | naseseazine C, C3-aryl pyrroloindolines | Streptomyces sp.
BGC0000046.4 |  | 0.35 | PKS | depudecin | Alternaria brassicicola
BGC0002227.3 |  | 0.31 | NRPS | AKML B, AKML D, AKML A, AKML C | Aspergillus luchuensis IFO 4308
BGC0002667.2 |  | 0.30 | ribosomal | estericin A | Clostridium estertheticum
BGC0000688.4 |  | 0.29 | terpene | copalyl diphosphate | Diaporthe amygdali
BGC0001954.2 |  | 0.28 | NRPS, PKS | wortmanamide A, wortmanamide B | Talaromyces wortmannii
BGC0001366.5 |  | 0.27 | PKS | BE-24566B, zunyimycin A | Streptomyces sp. FJS31-2
BGC0002058.3 |  | 0.27 | NRPS, PKS | mutanocyclin | Streptococcus mutans B04Sm5
BGC0002287.2 |  | 0.27 | NRPS | mutanocyclin, leuvalin, tyrvalin | Streptococcus mutans

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001291.3 |  | 0.41 | ribosomal | enterocin NKR-5-3B | Enterococcus faecium
BGC0001948.3 |  | 0.37 | other (other) | naseseazine C, C3-aryl pyrroloindolines | Streptomyces sp.
BGC0000046.4 |  | 0.35 | PKS | depudecin | Alternaria brassicicola
BGC0002227.3 |  | 0.31 | NRPS | AKML B, AKML D, AKML A, AKML C | Aspergillus luchuensis IFO 4308
BGC0002667.2 |  | 0.30 | ribosomal | estericin A | Clostridium estertheticum
BGC0000688.4 |  | 0.29 | terpene | copalyl diphosphate | Diaporthe amygdali
BGC0001954.2 |  | 0.28 | NRPS, PKS | wortmanamide A, wortmanamide B | Talaromyces wortmannii
BGC0001366.5 |  | 0.27 | PKS | BE-24566B, zunyimycin A | Streptomyces sp. FJS31-2
BGC0002058.3 |  | 0.27 | NRPS, PKS | mutanocyclin | Streptococcus mutans B04Sm5
BGC0002287.2 |  | 0.27 | NRPS | mutanocyclin, leuvalin, tyrvalin | Streptococcus mutans

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 28.99 out of 30.25
Confidence: strong
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.08 out of 23.79
Confidence: medium
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.19 out of 30.25
Confidence: medium
CRP
Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.55 out of 19.26
Confidence: medium
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.50 out of 23.79
Confidence: medium
Additional weak hits (1):
NtrC
Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 20.68 out of 29.72
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CRP | Cyclic AMP receptor protein
ColR | Phenol-responsive regulator
IolR | Regulator of the inositol catabolism

NZ_LR607361.1 - Region 3 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,702,949 - 2,723,830 nt. (total: 20,882 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Hydrolases: peptidase
FN738_RS11440: methionine aminopeptidase

smcogs
  SMCOG1172: methionine aminopeptidase

Ligases: synthetase
FN738_RS11405: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0002398.2 |  | 0.39 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0002309.2 |  | 0.36 | terpene | cattleyene | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000639.3 |  | 0.34 | terpene | carotenoid | Enterobacteriaceae bacterium DC260
BGC0000642.3 |  | 0.34 | terpene | carotenoid | Enterobacteriaceae bacterium DC413
BGC0001605.3 |  | 0.32 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001075.5 |  | 0.31 | PKS, terpene | aurachin RE | Rhodococcus erythropolis
BGC0001456.3 |  | 0.30 | terpene | isorenieratene | Streptomyces argillaceus
BGC0000286.3 |  | 0.30 | PKS | viguiepinol | Streptomyces sp. KO-3988

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0002398.2 |  | 0.39 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0002309.2 |  | 0.36 | terpene | cattleyene | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000639.3 |  | 0.34 | terpene | carotenoid | Enterobacteriaceae bacterium DC260
BGC0000642.3 |  | 0.34 | terpene | carotenoid | Enterobacteriaceae bacterium DC413
BGC0001605.3 |  | 0.32 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001075.5 |  | 0.31 | PKS, terpene | aurachin RE | Rhodococcus erythropolis
BGC0001456.3 |  | 0.30 | terpene | isorenieratene | Streptomyces argillaceus
BGC0000286.3 |  | 0.30 | PKS | viguiepinol | Streptomyces sp. KO-3988

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP

Genes with terpene domains:
FN738_RS11405: PT_FPPS_like
Domain 1 (29 - 276): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:
  IPP, DMAPP → FPP

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.38 out of 27.78
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.87 out of 28.19
Confidence: medium
Additional weak hits (1):
OsdR
Description: Development and stress management regulator
Species: Streptomyces coelicolor
Score: 17.93 out of 30.12
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
ZuR variant 1 | Zinc-responsive repressor