LOCUS       NZ_CABGTR010000003     22985 bp    DNA     linear   CON 13-OCT-2024
DEFINITION  Enterococcus faecalis strain 4928STDY7071622, whole genome shotgun
            sequence.
ACCESSION   NZ_CABGTR010000003
VERSION     NZ_CABGTR010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Enterococcus faecalis
  ORGANISM  Enterococcus faecalis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUL-2019) WTSI, Pathogen Informatics, Wellcome Trust
            Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_902161995.1-RS_2024_10_12
            Annotation Date                   :: 10/12/2024 01:27:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,759
            CDSs (total)                      :: 2,695
            Genes (coding)                    :: 2,666
            CDSs (with protein)               :: 2,666
            Genes (RNA)                       :: 64
            rRNAs                             :: 4, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 29
            CDSs (without protein)            :: 29
            Pseudo Genes (ambiguous residues) :: 0 of 29
            Pseudo Genes (frameshifted)       :: 12 of 29
            Pseudo Genes (incomplete)         :: 16 of 29
            Pseudo Genes (internal stop)      :: 4 of 29
            Pseudo Genes (multiple problems)  :: 3 of 29
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:08:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 110718
            Orig. end                         :: 133703
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CABGTR010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22985
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22985
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22985
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12985](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12985
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            186..1667
                     /locus_tag="FN307_RS09500"
     CDS             186..1667
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368476.1"
                     /locus_tag="FN307_RS09500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_002401139.1"
                     /transl_table=11
                     /translation="MILMMFLNKVDKRKIALFQLLENAPMLTESKETVMQELELSEFIV
                     NKTVAELNADFIEFGLSEDFQIVSDGIFLTLNESGTETSATLIDCYIKESLRFAMFQDF
                     FFQRFDSVNEFALEHFVSHTLAYKEFKELKKILENYQITINKEFHLVGNETNLREVTTL
                     VFLQLYQRDFSLYGKKVLEQIRNFELFFSEKVHLNQRAGYAQAKCFHFLAVSLVRTQQQ
                     FYVEKKVDSQVLKQLAGDNQQNVFNWLESLQVPEPQRTNEGNYLLLFLIAEEWLQVASA
                     ALCQRFAEIQQLNRDLLSYLKIQFQLSEEVLQGFEQKVTIVHFKLFHFPIEANYSYRKM
                     DITYFAETYTEYFSASRQFIQEQKTNPAVWDARQFLFYRYLLLMVDALPLKKVLAPITL
                     CVDFSFGEAYNRMIQKNIEKITEWNIIFKAHVDESVQLILSDIHFVDWPEITQIIWLAP
                     PRPVDWSHFIKTLSALRPHSGEENKVGTAPLSSEK"
     gene            1904..2401
                     /locus_tag="FN307_RS09510"
     CDS             1904..2401
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618616.1"
                     /locus_tag="FN307_RS09510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_142665459.1"
                     /transl_table=11
                     /translation="MVFDGWKRKKQIRALETLVDTKYEKMYRIAFNYTHSKEDALDVIQ
                     ESFEKALKAIQKGPDIKDFEAWFFRILFSVATDYWRKKKREAVHIEKDEHVLALLNNPQ
                     RSFLEIEEIINQLDSPNREIILLKFFEGFTLKEIALILDINENTIKTKMYRSLNELRSL
                     LN"
     gene            2426..3310
                     /locus_tag="FN307_RS09515"
     CDS             2426..3310
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402522.1"
                     /locus_tag="FN307_RS09515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RsiV family protein"
                     /protein_id="WP_002365402.1"
                     /transl_table=11
                     /translation="MEDFVKSVVKNFSKEYRQQPLPTDLQAEVKARFHKEKKRYTWLRF
                     RNRSLQSSLVVACGFVLSVNLFPGFSEAARNIPVLDKIVQLVTIKTLTAKKQESEVNID
                     VPKIQTSQESSVADTLNKKYLKEAQTEFQQVKGQLFDGSRVSVTGDYEKVVDDRRFLVV
                     KRTFTEIKGSSATTTKYDTIDKRANVVVSLPLIFKNDFYIDVISSEIKQQIADQMKNDS
                     NKIYWSEKEDAPSDVQPFKKIKKDQPFYINEKHQLVIVFPQGEIAPYYMGTPEFVIPNQ
                     VIENELAAPNYLK"
     gene            3440..4576
                     /locus_tag="FN307_RS09520"
     CDS             3440..4576
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002365400.1"
                     /locus_tag="FN307_RS09520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ArgE/DapE family deacylase"
                     /protein_id="WP_002424922.1"
                     /transl_table=11
                     /translation="MEKSEKISILQDVVKIKSVNGNEEEVAIYLQNLLKKYEIPSELVS
                     YAPNRSSLVAYLGENREKVLGFSGHMDVVSEGDESQWTFPPFAAHIEGNKLYGRGSTDM
                     KSGLVAMVLAMIELKEKEVPLNGAVKFLGTVGEEVGELGAGQLTEKGYADDLSALVIGE
                     PTNYNLMYAHMGSINYSVVSHGKEAHSSMPEEGINAINNLNEFITEANQQMAEVTANYE
                     NPELGRTIHNVTVIKGGTQVNSIPGQAALQGNIRSIPEFSNDQVIALLQKIVDELNKKE
                     KHQLELTIDYNKIPVKAEKDSALIQAIQAQFDQPLPLVTSAGTTDLAEFTKSDNTFDCV
                     VFGPGVTTTAHQVDEYVEIDNYLDMIDKYQAIAKSYLN"
     gene            complement(4629..5420)
                     /locus_tag="FN307_RS09525"
     CDS             complement(4629..5420)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367471.1"
                     /locus_tag="FN307_RS09525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002367471.1"
                     /transl_table=11
                     /translation="MDLHLTVDLKKTKTLIDLADQAHLIIEQTTKLPKKEAAILFLLRD
                     NQLVALGLAEEKATYKEVSFDHSILLKPTWDTELAYLAQAFLDDAKESGLTLEATPTTV
                     KIPKSAVATVTNYKETVTFILERFGYSLFKKPAPKKARPAKARHKWTKEVSQIPFYIDT
                     RQSKATVFWQKRNEMLIKAGATMMPEAPLNKDGSVGFSARFGEKLRDERKGQFKDFVTT
                     EDIVLKSVNEVGLFLYFAGTNSWLELVDENGKTLNEWTVVE"
     gene            5584..5967
                     /locus_tag="FN307_RS09530"
     CDS             5584..5967
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354850.1"
                     /locus_tag="FN307_RS09530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YccF domain-containing protein"
                     /protein_id="WP_002365398.1"
                     /transl_table=11
                     /translation="MKTLGNILWFIFGGFFGGLSWLFAGVIWCITIIGIPIGLQCFKLA
                     GLSFWPFKKRVVYSDSGVSLVVNIIWLIISGLPLAIGHCISGLFLCLTIIGIPFGQQSF
                     KLAKLALMPFGARVVSTNDFYFE"
     gene            6056..6481
                     /locus_tag="FN307_RS09535"
     CDS             6056..6481
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383201.1"
                     /locus_tag="FN307_RS09535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_002383201.1"
                     /transl_table=11
                     /translation="MAMSTKLSVAIHILSLIETGPQEQVTSEYIASSVNTNPVVVRRLM
                     SQLKKAGLIHSMRGANKNTLLKKPEEISLYEIYTAVELEREIFNIHQNPNPNCSVGANI
                     QSVLETEFTKVQQKMEEELKSITLADVIHEIEVKRDK"
     gene            6540..7169
                     /locus_tag="FN307_RS09540"
     CDS             6540..7169
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354854.1"
                     /locus_tag="FN307_RS09540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_002365397.1"
                     /transl_table=11
                     /translation="MIYMKVAVLGATGKEGQLLLAEAKRRGMDVTAIVRNASKITDGTP
                     TIEKDVYQLTTEDIQAFDVLISALGFPDVQDFPKSTQHLIEILTNQKTRLFVVGGAGTL
                     YVDPEHTTQLKDTPSFPAEIQPLASAMGEALNLLKEAQNIHWTYISPAAMFDADGPATG
                     HYEVAGEELTTNSQGDSYISYADYAVAMLDEVESNAHPNQRISVYQ"
     gene            7798..7887
                     /locus_tag="FN307_RS14640"
     CDS             7798..7887
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013828.5"
                     /locus_tag="FN307_RS14640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_229201793.1"
                     /transl_table=11
                     /translation="MNLRYEKKSTVLTSNIALFQWTEVFQDKR"
     gene            complement(8294..8647)
                     /locus_tag="FN307_RS14520"
     CDS             complement(8294..8647)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407847.1"
                     /locus_tag="FN307_RS14520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_025186412.1"
                     /transl_table=11
                     /translation="MSNEVKKMISLTWILFLVSIVTMISIGITFKFWGLKGLLIPVFEC
                     SLIAYIGFKIEIIRRRINIKSYNELLNILHYDSLKSTTSPSKKNFFLEKNLLAFLISFV
                     FFLLIISISFVIF"
     gene            complement(8765..9268)
                     /locus_tag="FN307_RS09555"
     CDS             complement(8765..9268)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002424923.1"
                     /locus_tag="FN307_RS09555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_002424923.1"
                     /transl_table=11
                     /translation="MNTGEKIRKYRMEKNLSQVELSSILLVSRQTISNWENGRTRPEME
                     NLVLISNFFDVPLEVFLSEDISEIKKQHTEFTFTAKIIFIIFISICVLISSIFMSIKMS
                     KYFLVFPFLLLNIIFACLLTFFLRQTPEKSYLKKFNKLNFLFIILIMGLISFFSIYFLL
                     TLLN"
     gene            9422..9631
                     /locus_tag="FN307_RS09560"
     CDS             9422..9631
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0005488 - binding [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401134.1"
                     /locus_tag="FN307_RS09560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lichenicidin A2 family type 2 lantibiotic"
                     /protein_id="WP_002401134.1"
                     /transl_table=11
                     /translation="MEAEKIVGMQFEDLSKEEMNFIAGGNNNARISPTIVTPVTPYTSY
                     VASAAGSAALSAVSGLVSYTKKCF"
     CDS_motif       9422..9448
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEAEKIVGM"
                     /locus_tag="FN307_RS09560_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9449..9631
                     /prepeptide="core"
                     /locus_tag="FN307_RS09560_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="1.60"
                     /molecular_weight="6041.7"
                     /monoisotopic_mass="6038.1"
                     /core_sequence="QFEDLSKEEMNFIAGGNNNARISPTIVTPVTPYTSYVASAAGS
                     AALSAVSGLVSYTKKCF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEAEKIVGM"
                     /leader_location="[9421:9448](+)"
                     /alternative_weights="6059.7"
                     /alternative_weights="6077.8"
                     /alternative_weights="6095.8"
                     /alternative_weights="6113.8"
                     /alternative_weights="6131.8"
                     /alternative_weights="6149.8"
                     /alternative_weights="6167.9"
                     /alternative_weights="6185.9"
                     /alternative_weights="6203.9"
                     /alternative_weights="6221.9"
                     /alternative_weights="6239.9"
                     /alternative_weights="6258.0"
     gene            9652..9849
                     /locus_tag="FN307_RS09565"
     CDS             9652..9849
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0005488 - binding [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396812.1"
                     /locus_tag="FN307_RS09565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lichenicidin A2 family type 2 lantibiotic"
                     /protein_id="WP_002396812.1"
                     /transl_table=11
                     /translation="MDEKQLDSLVGQKFEDLSKEEMNFIAGGNDNARISPTIILSAATV
                     ASAASSFVGSYTLSAFTKCR"
     CDS_motif       9652..9735
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDEKQLDSLVGQKFEDLSKEEMNFIAGG"
                     /locus_tag="FN307_RS09565_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9736..9849
                     /prepeptide="core"
                     /locus_tag="FN307_RS09565_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-0.50"
                     /molecular_weight="3594.0"
                     /monoisotopic_mass="3591.9"
                     /core_sequence="NDNARISPTIILSAATVASAASSFVGSYTLSAFTKCR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDEKQLDSLVGQKFEDLSKEEMNFIAGG"
                     /leader_location="[9651:9735](+)"
                     /alternative_weights="3612.0"
                     /alternative_weights="3630.1"
                     /alternative_weights="3648.1"
                     /alternative_weights="3666.1"
                     /alternative_weights="3684.1"
                     /alternative_weights="3702.1"
                     /alternative_weights="3720.2"
                     /alternative_weights="3738.2"
                     /alternative_weights="3756.2"
                     /alternative_weights="3774.2"
     misc_feature    9953..9966
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.36"
                     /tool="antismash"
     gene            10001..12985
                     /gene="lanM"
                     /locus_tag="FN307_RS09570"
     CDS             10001..12985
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401133.1"
                     /locus_tag="FN307_RS09570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_002401133.1"
                     /sec_met_domain="DUF4135 (E-value: 1e-88, bitscore: 292.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7.3e-49, bitscore:
                     160.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNCFEKGKALTIEERMSLIKNKIFDDKNSSNIQRWLNRKTTVDSE
                     LFSKILNINNWKLEEFNHCIDENFKIDSYSDRVTYSDFDSLIASIEDQNNLPSTYVKLI
                     RPFLTKLENGLIVDFQDKLSEKAIENIFDCLASRLINLSLKVFVLEMDFIKNSNGLHGE
                     TSKERFINFIDLYDDKEKLLNLYQKYPVMTRKLSITTLYFIDFMNEFLNNLFQSWDSIE
                     DTFFDTEEKIYVESLIFEKGDTHEKGKSVVIIEFNLGKIVYKPRNLYIEKNFQKIIKFF
                     SYSNGFLNMDIPKSLYNSTFTFVQFIEQEPCNNEEEIERFYQRYGQLIALIYLTNGSDI
                     HFENVISHGEYPVIVDYETLFSVPIKLEGRQENIFSEIVGVIRNSVSSSIMLPGKMQLD
                     SEGNSVDISGLSGKTQKLEKKMYVPKNLDNDNAKFVLENVILEGSNNNVFYKDKLINYQ
                     DYYKEIIAGFSNVMDFFLVNKEEYLNLIEGMENNTIRILARNTNTYAQFLEFTKHPNCL
                     KDFVELEKILENLYTFPYENKQISQLEYKDMVFDDIPIFFSKLDENCIYNSEGVRIQNV
                     FENTPRIFLIDKIKNIDSENISKQIGIIMMKIKGEEGVVKQDVSSLVISKEDSYLQIAE
                     KLAEKLIDSAYIDKNEEYMTWLVINDGVVDEFDLGASKVNFYDGLIGIASLFKSLYKVT
                     GKVKYQRYFDYLVKTTMDLLDTMQTDSAYVGFHSFLQLFSIIEKEDTNYERITHYLNLL
                     QQNSQNFLEREGTVDWLLGYGGIIPLYIDVYKKTKDNQYLEIAIFLGNKLIMFAEKDTN
                     VMKNIGIGHGISGLLISMVELYKVTKDRQYLEYIKKLNERMSISLVQENEDVVSWCNGI
                     LGYLLGQSYLHKNNIKSALSDKEKQRLLLKIKNQYLESDCLCHGNCGIIQFYIDLYLLE
                     NSDKYLEHAKKIGNKMISEIIKNEYIQIREFEGFDNIGLFNGISGVAYTLVRLLEPENV
                     PSVFV"
     gene            13011..13712
                     /locus_tag="FN307_RS09575"
     CDS             13011..13712
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010710868.1"
                     /locus_tag="FN307_RS09575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavodoxin family protein"
                     /protein_id="WP_010710868.1"
                     /transl_table=11
                     /translation="MKKILAIIGSRDKNSETLSIVNRIKETVQDLNASFEFEIITPYDY
                     NLNFSDSPRLAFIKGADTNEQDERDDSKKIKAKIENASLVILASPTYFANVSADIKLFI
                     DRFCHLAHLFYFAKKPCITVVTSDGNGHIQTSNYLKSFCDGLGMVRVQEIISIRSNPIS
                     ENEIEASVREGLKYISNPQKISPNLSMEMSFQHWKKSISKQNETLSEYRYWENSGLFSC
                     NSLEEYFDRYR"
     gene            13719..15848
                     /locus_tag="FN307_RS09580"
     CDS             13719..15848
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002424924.1"
                     /locus_tag="FN307_RS09580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_002424924.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 7.7e-34, bitscore:
                     110.5, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNIKVVYQNEHSECGIAVVTSILNFFGSRVTINDLRDKYGSPKG
                     GLTFGNMNYIMKKFGLIYHGIKINDTDYLKNQKKPVILFWDNNHFVVFYKYKRGHFYVM
                     DPKLGKVVYTKHEFEEHFSLYALVFKEINYNDGKKEIKINLKNKTKELICSLLRSTKSI
                     IILMIFVIFLSKMLSLIVPVLTQRLIDNYQILANLSLATLIGGTILIAGIYYLITVSYS
                     LLLTKLQLSWSKKLSNKFMEKVFIKSLNFFVNRSSGSMIYKANLITMVQQMLSKNTIEN
                     IIDYLFMIVYFIYLTNYSSKLTIITIIFCLLILINSLTYSKINYKINGRVIEYQSEIQS
                     LYVEIFSGMETIKSLGKEKVFFTRWSNIFSNSLKSLSQQGKAAAWLSGISTTLLFTLPI
                     IILFFGIHEVQANQMSLGQLIGFTTLIAYFIEPFSTMIGSISQILILKSYLNQISDVTN
                     TDFYNEINGKKKFERFENLKMNNVNFSFSEFEKNVISSVNLEIKKGEKVAIVGKSGSGK
                     STLLKLICGLFIPSEGQVIYNNEEISSFDKSSLRNKVGYVTQSSIVFGNTLEENLMVGD
                     ESPIVVKEVLTATGINELVDNDMLGLNTIISENGMNLSGGQKQKISIARCLLKNPDVII
                     MDEPTSSLDNVSEKKIMDYILNNCKTSVIVAHRLNTIKNMDRIIVLDKGRVVEEGNHEQ
                     LLEMQKVYYSLYNEM"
     gene            15852..16115
                     /locus_tag="FN307_RS09585"
     CDS             15852..16115
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396818.1"
                     /locus_tag="FN307_RS09585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002396818.1"
                     /transl_table=11
                     /translation="MRYSLEDRADNRINAVAAVYKDESKDLIRESNTHRCGVCGEEKTC
                     TTILDFDNLIRKNMLNIKYDYKFNQCVALYDRKEEFNLVKRM"
     misc_feature    complement(15856..15873)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 24.35"
                     /tool="antismash"
     CDS             complement(16586..16729)
                     /gene="allorf_127304_127447"
                     /locus_tag="allorf_127304_127447"
                     /protein_id="allorf_127304_127447"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLLLIKTYNYLHSYFILKKYGPVNTSLVHIGGAPRNICTENSDSD
                     YL"
     CDS_motif       complement(16631..16729)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MLLLIKTYNYLHSYFILKKYGPVNTSLVHIGGA"
                     /locus_tag="allorf_127304_127447_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16586..16630)
                     /prepeptide="core"
                     /locus_tag="allorf_127304_127447_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.70"
                     /molecular_weight="1572.6"
                     /monoisotopic_mass="1571.7"
                     /core_sequence="PRNICTENSDSDYL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLLLIKTYNYLHSYFILKKYGPVNTSLVHIGGA"
                     /leader_location="[16630:16729](-)"
                     /alternative_weights="1590.7"
                     /alternative_weights="1608.7"
     gene            <16738..>16842
                     /locus_tag="FN307_RS14750"
                     /pseudo=""
     CDS             16738..>16842
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /locus_tag="FN307_RS14750"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="antitoxin"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDDEIDLKTLRNAMEISKEKKEIGISQEQMEKLLN"
     gene            <16845..16949
                     /locus_tag="FN307_RS09590"
                     /pseudo=""
     CDS             <16845..16949
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]"
                     /GO_function="GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]"
                     /GO_process="GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /locus_tag="FN307_RS09590"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /pseudo=""
                     /transl_table=11
                     /translation="RYRIGNYRILANICDSKVVIQIFPIGHKGTIYKE"
     gene            complement(17176..18381)
                     /locus_tag="FN307_RS09595"
     CDS             complement(17176..18381)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627528.1"
                     /locus_tag="FN307_RS09595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002401127.1"
                     /transl_table=11
                     /translation="MSVVLVLLGLLGLLVSGGLTIKALIKKQPKKQYGYAALASAALFI
                     GGVATTDSSPTLSLDAESIETDANGSATIKGEYDGNSKLTANGKEVKTKDKTFAYKVKL
                     SDEKTQKITFVAEKKDTKVEKSVEVTPSKEFIASITDSEQELAKTEKALAYAEKQPSQK
                     NYDEAATLVSSLSQEYEEYNDRLEKIKEAVPVDEAVTTAEKSKSKSDYQAAEKLVAAAP
                     VGKEGFQQRLTTVQTAIAEKEKNEQLVASATAAVEKAEQEPTNEAYYNEAIKQIDALNS
                     PNQALTKRVAVVKTQLDAHKEKQRKEAEAQKLAAEKAQKEQAEAAAKAQAEAEAQQAAQ
                     APAEVETAAAEAPSGNALIKGSRNGIYHVPGSRYYNRTTNPVAWFSTVEEAEAAGYRAP
                     KQ"
     gene            18573..19817
                     /locus_tag="FN307_RS09600"
     CDS             18573..19817
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002365395.1"
                     /locus_tag="FN307_RS09600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="competence/damage-inducible protein A"
                     /protein_id="WP_142665460.1"
                     /transl_table=11
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDN
                     GGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQVVAQHLHKSLVEDQEGLNRLHQFFQ
                     QSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMFQQA
                     ARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRL
                     TVKTKDLVAGEELLTATEEKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESL
                     TAGLFQSTLGEIAGASKIFKGGFVTYLQETKENFLGISHELLEEHGTVSEACAKEMAEK
                     ARQLAKSNYGLSFTGVAGDSIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAV
                     MRGLDLLRRRIINKK"
     misc_feature    19822..19837
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.58"
                     /tool="antismash"
     misc_feature    complement(19823..19836)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 22.72"
                     /tool="antismash"
     gene            19931..20977
                     /gene="recA"
                     /locus_tag="FN307_RS09605"
     CDS             19931..20977
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="recA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354860.1"
                     /locus_tag="FN307_RS09605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="recombinase RecA"
                     /protein_id="WP_002354860.1"
                     /transl_table=11
                     /translation="MADDRKVALDAALKKIEKNFGKGSIMKLGEKADQKISTIPSGSLA
                     LDVALGVGGYPRGRIIEVYGPESSGKTTVSLHAIAEVQRNGGTAAFIDAEHALDPQYAE
                     KLGVNIDELLLSQPDTGEQGLEIADALVSSGAIDIVVIDSVAALVPRAEIDGEMGASHV
                     GLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPETTPGGRALKFYATVRL
                     EVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKVAEVDIMYGQGISQEGELLDMAVEKD
                     LISKSGAWYGYKEERIGQGRENAKQYMADHPEMMAEVSKLVRDAYGIGDGSTITEEAEG
                     QEELPLDE"
     misc_feature    complement(21084..21098)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.0"
                     /tool="antismash"
     gene            21374..22930
                     /gene="rny"
                     /locus_tag="FN307_RS09615"
     CDS             21374..22930
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_process="GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rny"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /locus_tag="FN307_RS09615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonuclease Y"
                     /protein_id="WP_002354863.1"
                     /transl_table=11
                     /translation="MVLNILLAIVGLIVGLGLGFVIAKSRHDKAINGAKISASSILENA
                     RKESETLKKEALLEAKEENQKYRSEIESELKESRLELKSQENRLIQREQTLDRKDDSLE
                     KREGSLEEKEEKLGARQQLIDEREKEVENLINQQHQELERIASLSKEEAKSIIMKSTEE
                     ELNHELTLMVKESEQRAKEESDRKAKNLLSLAIQRCAADSVSETTVSVVTLPNDEMKGR
                     IIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGRIHPAR
                     IEEMVEKSRKEMDERIREYGEQAAFEVGAHTLHPDLIKILGRLRFRTSYGQNVLNHSIE
                     VAKLAGVLAAELGEDVQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYKENSVVIN
                     AIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLENLENISNSFEGVDS
                     SFAVQAGREVRVMVKPEEISDLESVRLVRDIRKKIEDDLDYPGHIKVTVIRETRAVDYA
                     K"
ORIGIN
        1 aaaagaaaaa aagaaacaaa caaaagaaac aacggctcat cccctacaag tgaataaaga
       61 ttttgtcttt cctaacggac ttggtgcagg cggcgatgaa gaatctgaaa gctatttagc
      121 agcggttggg tactttcttt caggaaatgg attgtatggg aaaaaaatgg atgtgagaga
      181 agtctatgat attgatgatg tttttaaata aagtggataa aagaaaaatc gccttatttc
      241 agttactgga aaatgcaccg atgttaacag agtcaaaaga aaccgtaatg caggagttag
      301 aattatctga atttatcgtg aacaaaacgg tcgctgaatt aaatgccgat tttattgaat
      361 ttggtttatc agaggatttt caaattgtga gcgatggtat tttcttaacg cttaatgaat
      421 caggaacgga aacttccgct actttgattg attgctatat taaagagtcg ttacgttttg
      481 ctatgtttca agatttcttt tttcagcgtt ttgattctgt gaatgagttt gctttagaac
      541 actttgttag tcacacattg gcttataagg agttcaagga attaaagaaa atactggaaa
      601 attaccaaat tacaattaat aaagaatttc acttagtggg aaatgaaacc aatttacgcg
      661 aagtaacaac actggttttt ttacaattat accaacgtga tttttcattg tacggtaaaa
      721 aagttttaga gcagattcgg aactttgagc tatttttttc tgagaaggtt catcttaatc
      781 agcgtgcggg ctatgcacaa gctaaatgtt ttcatttttt ggcggtttct ttagtacgaa
      841 cgcagcaaca gttttatgta gagaaaaaag tagattcgca agtgttaaaa caattagccg
      901 gtgacaatca gcagaatgtt ttcaattggt tagagagtct tcaagtccca gaaccacaac
      961 gaacaaacga aggcaattat ttactcttat ttttaattgc tgaagagtgg cttcaagtag
     1021 cttcagcagc actttgccaa agatttgcag aaattcaaca attgaatcgt gacttgttaa
     1081 gctatttaaa aatacaattt cagctttctg aggaagtcct gcaaggtttt gaacaaaaag
     1141 taacaatcgt acattttaaa ttgttccatt ttccaataga agcaaactat agttatcgca
     1201 aaatggatat aacctacttt gcagaaacgt atacagagta tttttctgct agtcgacaat
     1261 ttattcaaga acaaaaaacg aatcccgctg tttgggatgc cagacagttt ttattttatc
     1321 ggtatctgtt gttaatggtg gatgcgttac cattgaaaaa agttttggct ccgattacat
     1381 tgtgtgtcga cttttccttt ggtgaagcct ataatcgtat gatacaaaaa aatattgaaa
     1441 aaattacgga atggaatatc attttcaaag cacatgtaga tgaaagtgta caattaattt
     1501 tatcggatat tcattttgtc gattggcctg agattactca aattatttgg ctagcgccac
     1561 cacgtcctgt tgattggtcg cattttatta aaacgctgag tgcactaaga ccgcactcgg
     1621 gagaagaaaa caaggttggg acagcaccgc ttagctccga gaaataagaa gaaatttccg
     1681 gaaattgttc tttaattttt ggataatttc ggcttatttc cgaaggagct ggttctgttc
     1741 ccgccgttta tcagattttg agcgtggagc aaaaatccaa agtgattttt gtaccacgct
     1801 ttttctttta gaatataaaa attaaaaata ataaaaaagt tgaaactttt tatgcttgtg
     1861 attcgtctat ataagtgtac aggaaaggag gttccagaaa tcgatggttt tcgatggttg
     1921 gaaaagaaaa aaacaaattc gcgcgttaga aacgcttgtg gataccaaat atgaaaaaat
     1981 gtatcgcatt gcctttaact atacacattc gaaagaagat gccttggatg tgattcaaga
     2041 aagctttgaa aaggcactga aggccatcca aaaaggaccc gatattaagg attttgaagc
     2101 gtggttcttt cgaattctgt tttctgtagc gacagattat tggcgtaaaa agaaacgaga
     2161 agctgttcat attgaaaaag atgaacatgt gttagccctt ttaaataatc cccaacgcag
     2221 ttttttagaa attgaagaaa ttattaatca attagatagt cccaatcgtg aaattattct
     2281 attaaaattt tttgaaggat ttacgctaaa agaaatcgcc ttgatcctgg atattaacga
     2341 aaacacgatt aaaacgaaga tgtaccgcag tttgaatgaa ctccgaagtc tattgaatta
     2401 gtaaaagaaa ggaagcgaaa aaataatgga agattttgta aaaagtgttg ttaaaaactt
     2461 ttcaaaagaa taccgccaac aaccgttgcc aacggatcta caagcggaag tcaaagcgcg
     2521 ttttcataaa gagaaaaagc ggtacacctg gcttcgtttt agaaaccgct cactgcaaag
     2581 tagtctagtg gtggcttgtg gctttgtctt atcagtcaat ttgtttccag gttttagtga
     2641 agcagcccgc aacattcctg tgttagataa aattgttcaa ttagtcacca tcaaaacgtt
     2701 gacagcgaaa aaacaggaaa gtgaagtaaa catcgatgtc cctaaaatcc aaacatccca
     2761 agaatcttca gtagccgaca cgctcaacaa aaaatacttg aaagaagccc aaacagaatt
     2821 tcaacaagtc aaagggcaat tgtttgatgg ttctcgtgtt tcagtcactg gagattatga
     2881 aaaagtcgtg gacgaccgtc gcttcctagt ggtcaaacga accttcacag aaattaaagg
     2941 cagttctgcg acgacaacaa aatatgacac catcgacaaa cgagccaatg ttgtcgtttc
     3001 actcccctta atttttaaaa atgattttta cattgatgtc attagtagtg aaattaaaca
     3061 acaaatagca gaccaaatga agaacgatag caataaaata tactggtccg aaaaagagga
     3121 tgcccccagt gatgttcaac ccttcaaaaa aattaaaaag gaccaacctt tctatatcaa
     3181 tgaaaaacac caattagtga ttgtgtttcc tcaaggagag attgcgcctt actatatggg
     3241 cacccctgaa tttgtgatcc ctaatcaagt cattgagaat gaattggcag cgcctaatta
     3301 tttaaaataa actcagcaaa aaacacgcga cagttttaag aaatgtcgcg tgttttttac
     3361 tgacctaacc aagtcagttg cggttttact gagagaagcg tacactagaa ttaagcataa
     3421 caagaaaggg cgaatggcaa tggaaaaatc agaaaaaatt agtattttac aagatgtggt
     3481 taaaattaaa tctgtaaatg gaaacgaaga agaagtggca atctatttac aaaatctttt
     3541 gaagaaatat gagatccctt ctgaacttgt ttcttatgca ccaaatcgta gtagtttggt
     3601 tgcttattta ggtgaaaacc gagaaaaagt cttagggttt agtggccaca tggacgtggt
     3661 ttctgaaggg gacgaaagtc aatggacttt cccgccattt gcggcccata ttgaaggaaa
     3721 taaattgtat ggccgtggct caacggacat gaaaagcggc ttagtcgcaa tggttttagc
     3781 aatgattgaa ttaaaagaaa aggaagttcc attaaatgga gcggttaaat ttttaggtac
     3841 agttggtgaa gaagtcggtg agctaggtgc tggccaatta actgaaaaag gctatgcgga
     3901 tgatttaagt gccttagtca ttggagaacc aaccaattat aacttgatgt atgcgcacat
     3961 gggttcaatt aactattctg ttgtgtcaca cggaaaagaa gcccacagtt cgatgccgga
     4021 agaaggcatt aatgcaatta ataatttgaa cgaatttatt acagaagcaa accaacaaat
     4081 ggcggaagtc acagcaaact atgaaaatcc tgaattaggt cgaacgattc acaatgtaac
     4141 cgtcattaaa ggtggcacac aagtgaacag tattccaggt caagcagcct tgcaagggaa
     4201 tatccgttca attccagaat tcagcaacga ccaagtcatt gcattattac aaaaaattgt
     4261 cgatgaattg aacaaaaaag aaaaacatca gttagaatta acgattgatt acaataaaat
     4321 tcctgtaaaa gctgagaaag attctgcgtt aattcaagcc attcaagccc aatttgatca
     4381 accattacca ttagtgacaa gcgctgggac cacagactta gctgaattta ctaaatcaga
     4441 caatacattt gattgcgttg tctttggacc aggtgtgacc actactgcac accaagtcga
     4501 cgaatatgtc gaaattgata attatttaga tatgattgat aagtatcaag cgatagcaaa
     4561 aagttattta aattaaaaaa atgtcgcgcc tgaatcataa aaatcaggtg cgacattttt
     4621 tataaggttt attccaccac agtccattca tttaaggttt tgccgttctc atcaactagc
     4681 tctaaccagc tgtttgttcc agcaaaatag agaaacaagc cgacttcatt aacgcttttt
     4741 aagacgatat cttccgttgt gacaaagtct ttaaattggc ccttgcgttc atcacgaagt
     4801 ttttcaccaa atctggcgga gaaaccgaca gacccgtctt tatttaaagg ggcttctggc
     4861 atcattgtcg cgccagcttt aataagcatt tcattgcgct tttgccaaaa aacagttgct
     4921 ttgctttgtc gagtatcaat ataaaaagga atttggctaa cttcttttgt ccatttgtgg
     4981 cgtgctttgg ctggtctggc tttcttcggc gccggttttt taaacagaga gtagccaaaa
     5041 cgttccaaga taaaggtgac tgtttcttta tagttagtca ctgtcgctac cgcacttttc
     5101 ggaattttga ctgttgttgg ggttgcttcc aatgttaaac cactttcttt cgcatcatct
     5161 aggaaagctt gcgctaaata ggcaagttct gtgtcccaag tcggtttcaa taaaatcgag
     5221 tgatcaaaag aaacttcttt atatgtagct ttttcttcag caagtcctaa agcaactagt
     5281 tggttatctc ttagcaagaa aagaatcgct gcctcttttt tcggtaattt agttgtttgt
     5341 tcaatgatta agtgggcctg atcggctaag tcaatgagtg tctttgtttt ttttagatca
     5401 acggttaaat gtaagtccat gaagtctgct cctttatcgt tagtttcttc attgtatcat
     5461 gaaacagcgt cttcgtcttt taacgagtca gcgaccttac aatattgttt gaaacaaaaa
     5521 gaagctttcg tggtatactt actcacatac ataattttta atgaggaaag tagaggaaca
     5581 agaatgaaaa cacttggcaa tattttatgg ttcatctttg gcggcttttt tggtggctta
     5641 tcttggctat tcgcaggcgt gatttggtgt attacaatta tcggtattcc gattggttta
     5701 caatgtttta aattagcggg gttgagcttt tggccgttta aaaagcgagt cgtgtatagt
     5761 gatagcggcg tatctttggt ggtaaacatt atttggctga ttatcagtgg actaccatta
     5821 gcaattgggc attgtattag tggcttgttt ctttgtctga caatcatcgg tattccgttt
     5881 gggcaacagt cctttaaatt ggcgaaatta gcgttaatgc cgtttggggc ccgtgttgtt
     5941 tcaacaaatg atttttattt tgaatagtca gaggtttctc attgacaaat aaaacgaaac
     6001 agcgtattct gtaaatgtaa caaataacgt tacatttggt ttggagtgat tagacatggc
     6061 catgtcaacg aaattaagtg ttgcgattca tattttaagt ttgattgaaa caggtcctca
     6121 agaacaagtg acttctgaat acattgcttc gagcgtgaat acgaatccag tcgttgttcg
     6181 acgactaatg agccagttaa aaaaagccgg cttgattcat tccatgcgtg gagccaataa
     6241 aaatacctta ttaaagaaac cagaagagat ctcactgtat gaaatttata cagcggttga
     6301 attggaacga gagattttca atattcatca aaatcctaat ccaaactgtt ccgttggggc
     6361 aaatatccaa tcggtactag aaactgaatt tactaaagtg caacaaaaaa tggaagaaga
     6421 attgaaaagc atcaccttag cagatgtgat tcatgaaata gaagttaaga gagataagta
     6481 atctctctac ttttaaagta ttaaatgtaa ctattttagt tctatttaaa aatgaaagga
     6541 tgatttacat gaaagtagca gtattaggag caacaggaaa agaaggacaa ttacttttag
     6601 cagaagctaa acgtcgtggg atggacgtga cagccatcgt tcgtaatgcc tcaaaaataa
     6661 cagatggcac accgaccatt gaaaaagatg tttatcaatt aacaacagaa gatattcaag
     6721 cgtttgatgt attaattagt gccttaggat tccctgatgt gcaagatttc cccaaatcta
     6781 cccagcattt gattgagatt ttaaccaatc aaaaaacgcg cttgtttgtc gttgggggcg
     6841 ctggaacctt gtatgtggac ccagaacaca caactcaatt aaaagataca ccatcattcc
     6901 cagcagaaat tcagccatta gcttcggcga tgggcgaagc tttaaactta ttgaaagaag
     6961 ctcaaaacat ccactggacc tatattagtc ctgcagccat gtttgatgct gatggtcctg
     7021 cgacaggcca ttatgaagtt gctggcgaag aattaacaac caatagtcaa ggtgacagct
     7081 acattagtta cgcagactac gccgttgcca tgttagatga agtggaaagt aatgcacacc
     7141 caaatcaacg aattagtgtg tatcaataaa agaaaaaatt attaatacaa aaaatatact
     7201 aagattagag gtatcctcta gggctgtttt aagcgtatag ttggttgtaa aaggaagacc
     7261 gaccacactc tctaggactg tgagtacaaa caaaaaatga tctccttcac tgtcatttaa
     7321 aatctggttt aagtatggta ggcttcgaga ccgtgtgtag gagatgaaaa tcatgtatgt
     7381 acttgcttta gatgtctcaa tgggaaaaag ttatgccgtt aaaaaagctc cgctcaaaaa
     7441 gctttaacga aagcacaagc tttactttcg ttggcataaa atacctatct agcagagtct
     7501 ggacaaacgt caatgaggtc taacccgccc tcaccaacta caatgaaaac aatcgagttt
     7561 cttttccaag ttaccttgag ggacaaacta aatcattata cttatttgta tcaaacatta
     7621 gctcatagaa tctgcgtata aaaagtattt acaaaataaa aagaccatag taaccgagaa
     7681 tgattaatat gggatatatc aatattgttt gactacgtaa ctaagtgaag gtagtctttt
     7741 ttgtttttag agtgaagttg tcgtataaaa aatagggcga atttcttttt ccagctcatt
     7801 aacttacgtt atgagaaaaa atcaacggtt ctaacatcca atatagctct gttccaatgg
     7861 acagaggtat tccaggataa aaggtaaaga atgtgattat tgatcatcta atccatcatt
     7921 ctaaaatttt atcaatcaat gagaaatctt atcgaatgaa agattacatg gaaacgaagg
     7981 gcctcgatat tgaaaaatag cagagagcca aaacatacat ctttatatgg cccttgacac
     8041 tgaatagatt ttgactataa aagtggttta gtattttaga tatatttaat tttagtttca
     8101 tgtcaatatt tattgacacc gctatttatc ggggcaaaag caccgccagc taaaaaggaa
     8161 attgatacag ctacagtaaa atcacttttt tgtaaattat acgtgtaaat gatcttgacc
     8221 tgacaaaaaa acagtaagtc agattaagat cattaaaaat aaatcgacaa aacaattatc
     8281 tattttaatt ttatcaaaat attacaaagc ttatcgaaat gattaatagg aaaaagacaa
     8341 aagagattag aaaagcaagc aggttttttt caaggaaaaa attttttttt gagggtgaag
     8401 ttgtagattt cagagaatca taatgtagaa tatttagcaa ttcattgtag gacttaatgt
     8461 tgattcttct tcttattatt tcaattttga aacctatata tgctattaaa ctacattcaa
     8521 aaacaggtat caataatcct ttcaaccccc aaaatttaaa agtaatacca atggaaatca
     8581 ttgttacgat ggatactaaa aataaaatcc aagttaaaga aatcattttt tttacttcgt
     8641 tactcatttc aattgctcct ttcagataat aatatatacg ttacaagtgt agcatataca
     8701 aaaataagaa ggattaatag cgtaatagtt ttatttagta aagactataa aggtttttta
     8761 cattttaatt taaaagagtt agcaagaaat aaatagagaa aaaactaatc aaacccatga
     8821 tgagaataat aaataagaag ttcaacttgt tgaatttttt taaataagat ttctctggtg
     8881 tttgcctaag aaaaaatgtt aatagacagg caaaaattat atttaatagc aaaaaaggaa
     8941 aaacaagaaa atatttactc atttttatag acatgaaaat acttgaaatc aatacacaaa
     9001 ttgaaataaa aattataaat ataattttag ctgtaaatgt aaattcggtg tgttgctttt
     9061 taatttctga gatatcttct gatagaaaaa cctctaatgg tacatcaaaa aaattactga
     9121 ttagtactaa attttccatt tctggtctag ttcgtccatt ctcccagttc gaaattgttt
     9181 gtctagaaac taatagtatt gatgaaagtt caacttgaga cagatttttt tccattctat
     9241 attttcgaat tttttctcca gtattcataa aaacctccgt tgataaaaga attaaccatt
     9301 tgtataatat gttttgcata tgtaaaatgt ataacaaatg gtactttatt ttttatatta
     9361 tcatgataac atgaagatgt gttaacacgc tatataattt ttgaaaggaa gggattgtat
     9421 tatggaagca gaaaaaattg ttggtatgca atttgaagat ttatccaaag aagagatgaa
     9481 ctttattgct ggaggaaata ataacgctag aatttctccg actattgtta ctcctgtcac
     9541 accatacaca agttatgttg catcagcggc tggctctgca gctttgtcag ctgttagtgg
     9601 tcttgtctca tatactaaaa aatgttttta atatgaaagg gagagattat attggatgaa
     9661 aaacaattag actcgttagt aggtcaaaaa tttgaagatt tatcaaaaga agaaatgaac
     9721 tttattgctg gtggaaacga taacgctaga atttcaccta caattattct ttctgctgcc
     9781 actgtagcaa gtgctgcaag ttcattcgta ggatcgtata cattgtctgc ttttacaaag
     9841 tgcagataat aaagtgtttt taattgataa gtagaaataa aaatatatgt ttcattctat
     9901 ttgttggaat ttgaaatgta tggaattaaa ttcaacgaat ttaattccat acatttttta
     9961 aaacaataat tatatacata atactttagg agggggattt atgaactgtt ttgagaaggg
    10021 gaaagcatta actatagagg aaagaatgag tttaattaag aacaaaatat ttgatgataa
    10081 aaatagtagc aacattcaaa gatggcttaa tagaaaaaca actgtggata gtgaactttt
    10141 cagtaagatt ctaaatatca ataattggaa actagaggaa tttaaccatt gtatagacga
    10201 aaattttaaa atagattctt acagtgacag agtgacgtac tctgatttcg atagcttgat
    10261 agcatctata gaggatcaaa ataacttacc tagtacctat gttaaattaa tcagaccatt
    10321 tttaacaaaa ctagagaacg gcttaattgt tgattttcag gataaattat cggaaaaagc
    10381 tatagaaaat attttcgatt gtttagctag tcgattaata aatctaagtt taaaagtctt
    10441 tgtgttagaa atggatttta ttaaaaatag caatggactt catggtgaaa catcaaaaga
    10501 aagatttata aattttatag atttgtatga tgataaagaa aaattgttga atctgtatca
    10561 aaaatatcca gtaatgacaa gaaaattgag tataacaacc ttatatttta ttgatttcat
    10621 gaatgaattt ctgaataatt tatttcaatc atgggattca attgaagata cattcttcga
    10681 tacagaagaa aaaatatatg tagaaagttt gatatttgaa aaaggcgata ctcatgaaaa
    10741 agggaaaagt gttgttatta tagagtttaa tttgggaaaa attgtttata aacccagaaa
    10801 cttatatata gaaaagaatt ttcagaaaat tataaagttc ttttcttata gtaatggatt
    10861 tttaaatatg gatatcccaa aatctttgta taattctaca ttcacttttg ttcaatttat
    10921 cgagcaagaa ccttgtaata atgaagaaga aattgaaaga ttttatcaac gatatggtca
    10981 gctaattgca ttaatctatt taactaatgg tagtgatatt cattttgaaa atgtaatttc
    11041 tcatggagag tatcctgtta tagttgacta tgaaactttg ttttcggttc ctataaaact
    11101 tgaaggaaga caagaaaata tattcagtga aattgtgggg gttattagaa attctgtatc
    11161 gtctagtatt atgctaccgg ggaaaatgca attagattca gaaggaaata gcgttgatat
    11221 tagtgggctt agtgggaaaa ctcaaaaatt agaaaaaaaa atgtacgttc caaaaaattt
    11281 agacaatgat aatgcaaaat ttgtattaga gaatgtcatt ttagaaggca gtaataataa
    11341 tgtgttctat aaggataaac ttattaacta tcaagattac tataaagaaa ttattgctgg
    11401 ttttagtaat gtaatggact tctttttggt taataaagaa gaatatctga atctaattga
    11461 aggcatggaa aataatacaa ttagaatatt agcaagaaat acgaacacat atgctcaatt
    11521 tttggagttt actaaacacc caaactgttt aaaagatttt gttgagttag aaaagatatt
    11581 ggaaaattta tatacattcc cttatgaaaa taaacagata tctcaattag agtataaaga
    11641 tatggttttt gatgatatcc caatattttt ttcaaagcta gatgagaatt gtatctacaa
    11701 ttcagaagga gttaggatac aaaatgtttt tgaaaatact cctagaatat ttttaattga
    11761 taaaattaaa aatattgatt cagaaaatat ttctaaacag atagggatta ttatgatgaa
    11821 aatcaaaggt gaagagggag ttgtaaaaca agatgtatca agtttagtaa taagtaagga
    11881 ggatagttac ctacagatag ctgaaaaatt agctgaaaaa ctaattgact cagcttatat
    11941 cgacaaaaat gaagaatata tgacttggtt ggttataaat gatggtgtag ttgatgaatt
    12001 tgatttaggt gcttcaaaag tcaattttta tgatgggtta ataggaattg catcattgtt
    12061 taaatcgtta tataaagtaa caggaaaagt aaaatatcaa agatattttg attatttagt
    12121 gaaaactacg atggatcttt tagatactat gcaaacagat agtgcttatg tagggtttca
    12181 ttcattttta caattgtttt ctataatcga aaaagaagat actaactatg aaagaattac
    12241 acattatttg aacctgttac agcaaaattc tcaaaatttt ttagaacgtg agggtacagt
    12301 agactggtta ttaggttatg gaggtataat cccattatat attgatgtgt ataagaaaac
    12361 caaagataat caatatttag aaatcgctat ttttttgggt aacaaattga taatgtttgc
    12421 tgaaaaagat acaaatgtaa tgaaaaatat tggtataggt catggcattt caggcttact
    12481 tatatctatg gttgaactat ataaagttac caaagatagg caatatttag aatatattaa
    12541 aaaattaaat gaaagaatgt ctatttctct agttcaggaa aatgaagatg ttgtatcttg
    12601 gtgtaatgga atattaggtt atctattggg acaatcttac cttcacaaaa ataatattaa
    12661 gagtgcatta tctgataaag aaaaacaaag attactatta aaaattaaaa atcaatactt
    12721 ggaatctgac tgtttatgtc atggtaattg tgggataatt caattttata ttgatttgta
    12781 tttattagaa aactctgata aatatttgga acatgcaaaa aaaataggta acaaaatgat
    12841 ttctgaaatt attaaaaacg aatatataca aataagagag tttgaagggt ttgataatat
    12901 tggtttattt aatggcatat ctggtgttgc atataccttg gttaggctat tagaaccaga
    12961 gaatgttccg tcagtttttg tttaaaaata tgaattatga ggagattatt atgaaaaaaa
    13021 tactagcaat tatcggttca agagataaaa atagtgaaac tctaagcata gtaaatagaa
    13081 taaaagaaac ggttcaggat ttgaatgctt cttttgagtt tgaaattatt actccttatg
    13141 attataatct aaatttttcc gatagcccta gattagcgtt tataaaagga gcagatacaa
    13201 atgaacaaga tgaaagagat gattctaaaa aaataaaagc aaagatagaa aatgcttcac
    13261 ttgttattct agcgagtcca acttattttg ctaatgtatc tgcagatatt aaacttttca
    13321 ttgatcgttt ttgtcattta gcacatttgt tttattttgc aaaaaaacca tgtatcactg
    13381 tggtaacgtc agatggaaat ggtcatattc aaacttccaa ctatttgaaa tctttttgtg
    13441 atggattagg aatggttaga gtacaagaaa ttatatcaat aaggagtaat cctatttctg
    13501 agaatgaaat agaagcatct gtaagagaag gactaaagta tataagtaat cctcaaaaga
    13561 tttcacctaa tttaagtatg gagatgtcgt ttcaacactg gaaaaaatct atttcaaaac
    13621 agaatgaaac gttgtcagaa tataggtatt gggagaatag tgggttattt tcatgtaata
    13681 gtttagaaga atatttcgat agatataggt aaatactcat gaaaaatata aaagtagttt
    13741 atcaaaacga gcatagtgaa tgtggtatag cagtagtaac aagcatttta aacttttttg
    13801 gatctagagt tactataaat gatttacgtg ataaatatgg aagtcctaaa ggtggtttaa
    13861 cttttgggaa tatgaattat attatgaaaa aatttggttt aatatatcat ggaataaaaa
    13921 taaatgatac tgactatttg aaaaatcaaa aaaagccagt tattcttttt tgggataata
    13981 accattttgt agttttttat aaatataaaa gaggtcattt ctatgtaatg gatccaaaat
    14041 taggaaaagt tgtttacaca aaacacgaat ttgaagaaca tttctcctta tatgcgcttg
    14101 tgtttaaaga aattaattat aatgatggaa aaaaagaaat taaaataaat ttgaaaaaca
    14161 agaccaaaga gttaatttgt agtctattac gtagtacaaa atcgataatt atacttatga
    14221 tatttgtaat ttttttatct aagatgttat cattgatagt tcctgttttg actcaaaggt
    14281 taatagataa ttatcagata ttagcaaatt tgtctttagc tactttaata gggggaacga
    14341 ttttaatagc aggaatatat tacttgataa cagtctctta tagtttattg ttaacgaaat
    14401 tgcaacttag ctggagtaaa aaattatcta ataaatttat ggaaaaagtt tttataaagt
    14461 cgttaaattt ttttgtgaac agatcatcag gttcaatgat ttataaagct aatttaatca
    14521 ctatggttca gcaaatgctt tcaaaaaata caatcgaaaa tatcatagat tatttattta
    14581 tgattgtata tttcatttat ttaactaatt attcaagtaa attgacaata attactatca
    14641 tattttgttt attaatatta attaattccc taacatattc taaaataaat tataaaatca
    14701 atggaagagt tatagagtac caaagtgaaa ttcaatcctt gtatgttgaa atattttctg
    14761 gaatggaaac aataaaatcc ttaggaaaag agaaggtttt ttttacaagg tggtctaaca
    14821 tatttagtaa cagtttgaaa agtttgagtc aacaaggaaa agcagcagca tggttatccg
    14881 gaatttctac tacgctactt tttactttac ctattattat tctttttttt ggtatacatg
    14941 aagttcaggc gaaccaaatg tctttaggtc aactaattgg ttttacaacc ttgatagcat
    15001 attttattga accattttct acgatgattg gttctatttc tcaaatttta attttgaaat
    15061 catatcttaa ccaaatatca gacgtcacaa acacagattt ctataatgaa attaatggta
    15121 aaaagaagtt tgaaagattt gaaaatttaa aaatgaataa tgtaaacttt tctttttcag
    15181 aattcgaaaa gaatgtaatt tcaagtgtga atttagaaat aaaaaaagga gagaaagttg
    15241 caatagttgg taaaagtgga agtggaaaaa gtacactctt aaaactaatt tgtggattgt
    15301 ttattcctag tgaaggacag gttatttata ataatgaaga aatatctagt tttgataaaa
    15361 gtagtttgag aaataaagtt ggatatgtaa cacaaagttc aatagtattt ggtaatacgc
    15421 tagaggaaaa tttgatggta ggtgacgaat cgcctattgt tgttaaagaa gtattgactg
    15481 ctacaggaat aaacgaactg gtagataatg atatgctcgg attgaataca ataatatcag
    15541 aaaatggaat gaatctttct ggaggtcaaa aacagaagat ttccattgca agatgcttat
    15601 taaaaaatcc agatgtaatt attatggatg aaccgactag ctcattagat aatgtatcag
    15661 aaaaaaaaat aatggattat attttaaata attgtaaaac tagtgtgatt gtggcacata
    15721 ggttgaatac aataaaaaat atggatagga taattgtttt agataagggt agagttgtag
    15781 aggaaggtaa tcacgaacaa ttgttagaaa tgcaaaaagt atattattct ttatataatg
    15841 agatgtaatg cttgagatac tctttagagg atagggcaga taacagaata aatgctgttg
    15901 ctgcagtcta taaggatgaa agcaaagact tgattagaga aagcaataca catagatgtg
    15961 gcgtatgtgg agaagaaaaa acttgtacaa ctattttaga ctttgataat ttaattagaa
    16021 agaatatgct taatattaaa tatgattata aatttaatca atgtgtggca ttgtatgata
    16081 gaaaagaaga atttaatctt gttaaaagaa tgtagttttg ccaaagtaat catcgagttt
    16141 tattatgttc tttgctgtgc aattaattta ttttggttac gaacattagt aacgagtatt
    16201 taatataata tagtgaagct aatttactta aaagtttgat ataaattcca ataaacagtg
    16261 tttttcaact ctataaaatt caggaacagt caaccaaggc ttaaaaaagc agcaaacaaa
    16321 agaaaagtcc cttgtcaaac gttaattttg caagggattt ttgataggaa accatatcat
    16381 tttttatgaa aatcaagctc tttagcaact ggaagatgtt ggtttatagg cgctccccat
    16441 ccatatcatg ttggctcttt attcccactc gacaataaca actgttggac accacatgct
    16501 aatttctgta tgaatgtttc agaaatatat tttgttttat atcttgaaaa ttctataagc
    16561 tgcttcaaat aaacgtttta cagatttaga ggtaatcact atcactattt tctgtacaga
    16621 tgttccgggg tgctcctcct atgtgtacta acgatgtatt gaccgggccg tattttttta
    16681 gtataaagta tgaatggagg tagttatatg ttttgatcaa caacaacatt tagaattctt
    16741 gatgatgaaa ttgacttaaa aaccttacga aacgcaatgg aaatttccaa agagaaaaaa
    16801 gagattggta tttctcaaga gcaaatggag aagttgttga atagcgctat agaattggaa
    16861 actatcgaat actggctaat atttgtgatt ctaaagttgt gatacaaata tttccaatag
    16921 gtcataaggg caccatttat aaagaataat ttattgtagt gacaaaaatc tgaaaacaaa
    16981 aaatagtatg aaaagaaagg ctataaactt ttaagttttg catataaacg aatctattta
    17041 acaaagtatt ctataaactt gaatgagtga agaaattaaa acatactaag attagagggt
    17101 aaattcaccc gtcgatgaat tcaccctcta atcttagtat gttttttttt gtttgattaa
    17161 ttattactaa tgtatttact gtttgggtgc tcggtatcct gctgcttctg cttcttcaac
    17221 agtagagaac caagctactg gattcgtagt tctattataa tatctacttc caggtacatg
    17281 ataaattcca ttacgtgacc ctttaattaa ggcgttaccg cttggtgctt ccgcagcagc
    17341 cgtctcgact tccgccggcg cctgtgcggc ttgttgcgcc tctgcttcag cttgcgcttt
    17401 tgctgccgct tcggcttgtt ctttttgcgc tttttcagcg gctagtttct gagcttctgc
    17461 ttcttttcgt tgtttttctt tgtgggcatc taattgagtt ttaacaacgg ctacccgttt
    17521 tgttaaagct tgatttgggg agtttaaagc gtcaatttgt ttgatcgctt cattatagta
    17581 agcttcatta gttggttctt gttcagcttt ttcaacagcg gcagttgcac tggcgactaa
    17641 ttgttcattt ttttcttttt cagcgatagc ggtttgaaca gtcgttaacc gttgttgaaa
    17701 tccttctttg ccaactgggg cagcagctac taatttttca gctgcttgat aatcgctttt
    17761 acttttagat ttttcagcag ttgtaactgc ttcatcaaca ggtactgctt ctttgatttt
    17821 ttcaaggcga tcattgtatt cctcgtattc ttgacttaat gaagatacta aggttgcggc
    17881 ttcatcatag tttttctgag aaggttgttt ttcagcgtaa gctaaggctt tttctgtttt
    17941 ggccaattct tgctcagaat ctgtgatgct cgcaataaat tcttttgatg gtgtgacttc
    18001 gactgatttt tcaactttgg tatctttctt ctcagccaca aaggtgattt tttgcgtttt
    18061 ttcatcggac agttttactt tgtaagcaaa cgttttgtct tttgttttta cttccttgcc
    18121 attggccgtt agtttgctgt tgccgtcgta ttcgcctttg atggtggctg agccattggc
    18181 atcggtttca atactctctg catcaagtga aagcgttggg gaagaatctg tcgtggcaac
    18241 cccaccaata aatagagcgg cacttgctaa tgcggcatag ccatattgtt ttttcggttg
    18301 tttcttaatt aatgctttga tagtcagtcc cccgctgaca agtaacccta atagacccaa
    18361 aagtactaat actacactca ttcatttctc tcctttcgat ataacgttat tatacaatgt
    18421 attgtgagaa aatgaacatt tttttcgtaa taattaataa atttcctgat aaaaaaatta
    18481 tttcctgaag ctcaaattct tttgtaaaaa ttttgttgtg ctaaaatgga aagtgagttt
    18541 aactacgtat gttattagag aaggggaaat caatgaaagc agaaatcatt gcagtcggaa
    18601 cagaattatt actgggacaa gtagtgaata ccaacgccac ctttttatca gaagagttag
    18661 ctgcgctagg catcgatgtt tactatcaga ccgttgttgg tgataacggc ggccgcttag
    18721 aaacgctact aacagaagca gaacaaagaa gtgatttaat tgtcctttgt ggagggctag
    18781 gacctacaga agacgattta accaagcaag ttgtcgcaca acatctccat aaatcattag
    18841 tagaagatca agaaggattg aaccgcttgc accagttttt ccaacagtct aagcggccaa
    18901 tgacggaaaa taatctacga caagtgttag ccattgaagg tggacaagtt cttcaaaacc
    18961 cgacaggatt agcggttggt tctttcgtaa cagaagggac aacaagctat ttgctcttac
    19021 cagggccgcc caatgaatta attccgatgt tccaacaagc ggcacgacct ttattgattg
    19081 atgcgtttcc acaagaagaa caattgattt cgagagtctt gcgtttttat ggcattggtg
    19141 aatcccagct ggtgaccgag attcaatcgt tgattgcgca ccaaacgaat ccaaccattg
    19201 cgccttatgc taagcctaat gaagtgacac ttcgtttaac agttaaaaca aaagacttag
    19261 tagctggcga agaattatta acagcgacgg aagaaaaggt tttagctaaa gtgggagact
    19321 atttttatgg gtatggggat gacaatagtt tagccaaggt aacagtggat ttgttattac
    19381 aaaacggaca aaccgttacg gctgctgaga gcctcaccgc tggcctattc caaagtacac
    19441 tgggggaaat tgcgggtgct tcgaagattt ttaagggagg cttcgtgacg tatttgcaag
    19501 aaacaaaaga gaacttttta ggaatttctc atgaactttt agaagaacat ggcacggtaa
    19561 gtgaagcgtg tgccaaagaa atggcagaga aagcgcgtca gttagctaaa tctaactatg
    19621 gtttatcatt tactggggtc gctggtgact caatcgaagg tcaaccgaca ggcactgttt
    19681 ggattgggct ggcggaagaa ggccaaccaa ccgttgcaga atgtttccat tttaaccgtg
    19741 accgaaatta tattagacag agtgcggtta tgcgagggtt agatcttttg cggcgccgaa
    19801 tcattaataa aaaataaata tgcgaatgtt tgttcggttt tttcttgctt ttttggtaca
    19861 aaagagatat gatagaccta ctaacaggaa atgaaaaata agtttatata aattaaagga
    19921 ggattatcca ttggcagatg atcgtaaagt ggctttagat gccgcactga aaaaaattga
    19981 aaagaacttt gggaaaggct ctattatgaa attaggcgaa aaagctgatc aaaaaatttc
    20041 aaccatccct agtggttctt tagcgttaga tgttgcattg ggcgtaggtg ggtatccacg
    20101 tggccgaatt attgaagtat atggtcctga gagttcaggt aaaacaactg tttctttaca
    20161 cgcaattgca gaagtgcaac gaaatggtgg aacagccgct tttatcgatg ctgagcatgc
    20221 attggatcct caatatgcgg agaaactagg cgttaacatc gatgaattac ttttatctca
    20281 accagatacg ggcgagcaag gcttagagat tgccgatgcc ttagtttcaa gtggtgcgat
    20341 tgacatcgtt gtcatcgact cggttgctgc gttagttcct cgtgcagaga ttgatggtga
    20401 gatgggagcg agccatgtcg gcttacaagc tcgactaatg tctcaagcac tacgtaaatt
    20461 atcaggctca attaataaga caaaaacaat tgctattttc attaaccaaa ttcgtgaaaa
    20521 agttggcgtg atgttcggaa atcctgaaac aactcctggt ggacgtgcat tgaaattcta
    20581 cgcaacggtt cgtctagaag tccgtcgtgc agaacagtta aaacaaggaa cagacatcgt
    20641 cggtaaccgc acaaaaatta aagtcgttaa aaacaaagtg gcgccaccat ttaaagtggc
    20701 agaagttgat atcatgtatg gccaaggtat ttcccaagaa ggcgaattac tagatatggc
    20761 tgtggaaaaa gaccttatca gtaaaagtgg tgcttggtat ggctacaaag aagaacgaat
    20821 tggccaaggc cgtgaaaatg ccaaacaata catggcggat catcctgaaa tgatggcaga
    20881 agtgtctaaa ttggtccgtg atgcatacgg catcggtgac ggttcaacca ttacagaaga
    20941 agcagaaggt caagaagaat tacccttaga cgaataaata acgagtgaat acgactcgtt
    21001 aagaagaagg acaacactta ctgaacagga caggtgttgt ctttttttgt ttagaactaa
    21061 attgttaaat agactgttgt ccatgtccga acccatccac atcaagcagc ttagtcaaac
    21121 agcagactat gcggcgtttg ttctaaaatt taaacaattc gtgacggcgg aaacctaaaa
    21181 atgtgacgtt gtctaatatt tgctgccctt tccaaaagaa agggcttttt taagttgaca
    21241 cctttcgcga caaacattag aataaaattg tgtgtatgca caaatatgca agtaggcata
    21301 ttgataattg attttagttt atcaaaaaac tacaagatat gaattaacaa aaagatagta
    21361 tggaggtgga aatatggttt taaatattct cctcgctatc gtcggtttga ttgtcggtct
    21421 tggtttagga tttgttattg caaagtcacg tcatgataaa gcaataaatg gtgcaaaaat
    21481 ttcagcgtcg agtattctcg agaacgctcg gaaagaatca gaaacactga aaaaagaagc
    21541 attgctagaa gctaaggaag agaaccagaa gtatcgttca gaaattgaaa gtgagttgaa
    21601 agaaagcaga ttagaactta aatctcaaga aaatcgttta attcaacggg aacaaacgtt
    21661 ggatcgtaaa gatgactctc ttgaaaaacg tgaaggctca ctggaagaaa aagaagagaa
    21721 acttggtgct agacagcaat taattgatga gcgagaaaaa gaagtagaaa acttaattaa
    21781 tcagcaacat caagaattag aacgaattgc ttccctttca aaagaagaag caaaatcgat
    21841 tattatgaag tcaacagaag aagagttgaa tcatgaacta accttgatgg tcaaggagtc
    21901 agaacaacgt gccaaagaag aatctgatcg caaagcgaag aacttgcttt ccctagcaat
    21961 tcaacgttgc gccgccgatt ctgtttctga aacaactgtt tccgtggtca ctttaccaaa
    22021 tgatgagatg aaaggtcgca ttattggtcg tgaaggacgt aatattcgta cattggaaac
    22081 attaacaggg attgacttaa tcattgatga tacgccagaa gcggttgtgt tatccggatt
    22141 tgatccaatc agacgagaaa tcgctcgaat gaccttggaa aaattaatcc aagatggtcg
    22201 gattcatccc gctcgtatcg aagaaatggt agaaaaatca cgtaaagaaa tggatgaacg
    22261 gattcgtgaa tacggagaac aagcagcctt tgaagtaggt gctcatacgt tacatcctga
    22321 tttaattaaa attttaggcc gtttacgttt cagaacaagt tatggtcaaa atgtcttgaa
    22381 ccactcaatc gaagtagcaa aactggctgg cgttttagcc gccgaattag gcgaagatgt
    22441 tcaattagcc aaacgtgcag gtttactaca tgatattggg aaagcattgg atcatgaaat
    22501 tgaaggttct cacgttgaga ttggcgcaga attagctgcg aaatataaag aaaattcagt
    22561 agttattaat gccattgcct cgcatcatgg tgatgtggaa gcaacctcag ttatttctgt
    22621 tttagtggca gccgcagatg cgttatctgc agcccgtcca ggtgcacgta gtgaatcgtt
    22681 agaaaactac attcgccgct tagaaaactt agaaaatatt tctaatagtt ttgaaggcgt
    22741 tgattcaagt tttgctgttc aagcaggacg tgaagttcgt gtcatggtga aaccagaaga
    22801 aatttctgat ttagaatctg ttcgtttagt tcgagacatt cggaagaaaa ttgaagatga
    22861 cttggattat ccaggacata tcaaagtaac ggttatccgt gaaacacgtg ccgttgacta
    22921 tgcgaaataa aataaaaagc gaataagtat cgcgtgtagt gtctcaacga acaattgcaa
    22981 ggatt
//
