LOCUS       NZ_CABGTR010000001     24382 bp    DNA     linear   CON 13-OCT-2024
DEFINITION  Enterococcus faecalis strain 4928STDY7071622, whole genome shotgun
            sequence.
ACCESSION   NZ_CABGTR010000001
VERSION     NZ_CABGTR010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Enterococcus faecalis
  ORGANISM  Enterococcus faecalis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUL-2019) WTSI, Pathogen Informatics, Wellcome Trust
            Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_902161995.1-RS_2024_10_12
            Annotation Date                   :: 10/12/2024 01:27:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,759
            CDSs (total)                      :: 2,695
            Genes (coding)                    :: 2,666
            CDSs (with protein)               :: 2,666
            Genes (RNA)                       :: 64
            rRNAs                             :: 4, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 29
            CDSs (without protein)            :: 29
            Pseudo Genes (ambiguous residues) :: 0 of 29
            Pseudo Genes (frameshifted)       :: 12 of 29
            Pseudo Genes (incomplete)         :: 16 of 29
            Pseudo Genes (internal stop)      :: 4 of 29
            Pseudo Genes (multiple problems)  :: 3 of 29
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:08:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 341168
            Orig. end                         :: 365550
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CABGTR010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24382
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24382
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24382
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14382](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14382)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(166..179)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
     gene            579..1136
                     /gene="frr"
                     /locus_tag="FN307_RS01705"
     CDS             579..1136
                     /GO_function="GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="frr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016626710.1"
                     /locus_tag="FN307_RS01705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribosome recycling factor"
                     /protein_id="WP_002356762.1"
                     /transl_table=11
                     /translation="MSKEVLATAKEKMTKAEESLRRELGQIRAGRANASLLDRIQVEYY
                     GAPTPVNQLASINIPEARVLMITPFDKNSIADIEKAIQMSDIGISPTNDGNVIRLVIPQ
                     LTEERRKELAKDVKKEAENSKVAVRNVRRDAMDELKKAQKNGDITEDELRSFEKDVQKL
                     TDDSIKNIDAITAEKEQELLEV"
     misc_feature    1259..1270
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.78"
                     /tool="antismash"
     misc_feature    complement(1430..1448)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 28.04"
                     /tool="antismash"
     misc_feature    complement(1431..1447)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.37"
                     /tool="antismash"
     gene            1506..2276
                     /gene="sufC"
                     /locus_tag="FN307_RS01710"
     CDS             1506..2276
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sufC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317772.1"
                     /locus_tag="FN307_RS01710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="WP_002356763.1"
                     /transl_table=11
                     /translation="MSVLEIKNLHVSIEDKKILKGVDLTINTGEIHAIMGPNGTGKSTL
                     SAAIMGNPNYEVTEGEILFDGVNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMRAA
                     INAKRDEDNKMSVMQFLKKLDSKMELLNMPEEMAERYLNEGFSGGEKKRNEILQLLMLE
                     PTFAILDEIDSGLDIDALKVVSKGVNEMRGENFGALIITHYQRLLNYITPDVVHIMMEG
                     RVVKTGGADLAKRLETEGYAGISQELGIDYKEEA"
     gene            2291..3577
                     /gene="sufD"
                     /locus_tag="FN307_RS01715"
     CDS             2291..3577
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sufD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634218.1"
                     /locus_tag="FN307_RS01715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="WP_002368983.1"
                     /transl_table=11
                     /translation="MKKVNLMDYLDEVTAFSLEHEEPAWMTELRTTALKNADESELPHI
                     DRVKFHRWPLLNVHMESYVPSEGNVASFDQMKDNPLIVQQGSFHAFEQLPASLAEQGVI
                     FTDIFTALQEHPELVKEYYMTKAVLPEEDKLTAAHAAFMNSGVFLYVPKNVVIEEPIES
                     LFIQDSDSNQPFFKHVLIVADNHSEFSYLERFQSTGHHAEKASGNIVVEVIAKDGAKVK
                     YSAVDQLGQTVTTYMNRRGYIMRDASVDWALGVMNDGDVVADFDSDLVGEGAHSEVKVV
                     AISAGKQTQGIDTRVTNKAPHSIGHILQHGVIRERGTLTFNGIGHILKGAKGADAQQES
                     RVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLRKEEAERLVIR
                     GFLGSVITAIPVKEVQNEFVEVIEGKLNA"
     gene            3574..4809
                     /locus_tag="FN307_RS01720"
     CDS             3574..4809
                     /EC_number="2.8.1.7"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (23-395). E-value: 1.1e-161.
                     Score: 529.8. Matches aSDomain:
                     nrpspksdomains_FN307_RS01720_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010712667.1"
                     /locus_tag="FN307_RS01720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cysteine desulfurase"
                     /protein_id="WP_010709740.1"
                     /sec_met_domain="Aminotran_5 (E-value: 6.6e-162, bitscore:
                     534.9, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.9e-10, bitscore:
                     36.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 7e-10, bitscore:
                     35.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMDAATIRQSFPILFQEVNDEPLVYLDNAATTQKPTAVLDILRHY
                     YETDNANVHRGVHTLAERATKDYEASREKVRQFIHAKETAEVLFTRGTTTSLNWIAKSY
                     GDLAVTAGDEIVISYMEHHSNIIPWQQLAQRTGAILKYIDVTEDGFLDMASARQQITEK
                     TKIVSIAHVSNVLGVINPIEELTQLAHQNGAVMVVDGAQAVPHMPVDVQAIDADFYAFS
                     GHKMCGPTGIGVLYGKRHLLEQMEPVEFGGEMIDFVHLQESTWKELPWKFEAGTPNIAG
                     AIALGAAIDYLTEIGLEAIHQHEAALVHYVLPKLQAIEGLTIYGPQNPKDHTGVIAFNI
                     EGLHPHDVATALDMEGVAVRAGHHCAQPLLNYLSVPATARASFYLYNTKEDADRLVEAI
                     KATKEFFQHGTF"
     aSDomain        3643..4758
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FN307_RS01720_Aminotran_5.1"
                     /evalue="1.10E-161"
                     /label="FN307_RS01720_Aminotran_5.1"
                     /locus_tag="FN307_RS01720"
                     /protein_end="395"
                     /protein_start="23"
                     /score="529.8"
                     /tool="antismash"
                     /translation="VYLDNAATTQKPTAVLDILRHYYETDNANVHRGVHTLAERATKDY
                     EASREKVRQFIHAKETAEVLFTRGTTTSLNWIAKSYGDLAVTAGDEIVISYMEHHSNII
                     PWQQLAQRTGAILKYIDVTEDGFLDMASARQQITEKTKIVSIAHVSNVLGVINPIEELT
                     QLAHQNGAVMVVDGAQAVPHMPVDVQAIDADFYAFSGHKMCGPTGIGVLYGKRHLLEQM
                     EPVEFGGEMIDFVHLQESTWKELPWKFEAGTPNIAGAIALGAAIDYLTEIGLEAIHQHE
                     AALVHYVLPKLQAIEGLTIYGPQNPKDHTGVIAFNIEGLHPHDVATALDMEGVAVRAGH
                     HCAQPLLNYLSVPATARASFYLYNTKEDADRL"
     gene            4796..5263
                     /gene="sufU"
                     /locus_tag="FN307_RS01725"
     CDS             4796..5263
                     /GO_function="GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sufU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362181.1"
                     /locus_tag="FN307_RS01725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="WP_002356768.1"
                     /transl_table=11
                     /translation="MALSKLDNLYRQVILDHSSHPHHHGTLDASSQTIELNNPTCGDVI
                     ELDVAIEDGVIKDIAFQGSGCSISTASASMMTDAVLGKTIAEATALAEDFSQLVQGNEV
                     AEDEKLGDAAMLSGVAKFPARIKCATLAWKALEQAVANNGQGEAGHLHCEK"
     gene            5282..6676
                     /gene="sufB"
                     /locus_tag="FN307_RS01730"
     CDS             5282..6676
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sufB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356769.1"
                     /locus_tag="FN307_RS01730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="WP_002356769.1"
                     /transl_table=11
                     /translation="MSTVPELEEYKFGFHDDVEPVFSTGDGLTEDVVREISRVKGEPEW
                     MLDFRLKSLEQFNKMPMQEWGPDLSDIDFSKIKYYQKPSDKPARDWDDVPDKIKETFEK
                     IGIPEAERAYLAGASAQYESEVVYHNMKEEFEKLGIIFTDTDSALKEYPDLFKEYFSKL
                     VPPTDNKLAALNSAVWSGGTFIYVPKGVRVDVPLQTYFRINAENTGQFERTLIIVDEGA
                     SVHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKAYEGA
                     TVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAPNTSSS
                     IVSKSIAKDGGEVNYRGQVTFGKDSAGSISHIECDTIIMDEKSKSDTIPFNEIHNSQVS
                     LEHEAKVSKISEEQLYYLMSRGLSEAEATEMIVMGFVEPFTKELPMEYAVELNRLISYE
                     MEGSVG"
     gene            complement(6762..>6899)
                     /locus_tag="FN307_RS14680"
                     /pseudo=""
     CDS             complement(6762..>6899)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367047.1"
                     /locus_tag="FN307_RS14680"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="EDIMYRVGHKDSKMTRQVYNYFYPERKERSADQFAQFIEKEKYLF
                     "
     gene            complement(7727..8278)
                     /locus_tag="FN307_RS01745"
     CDS             complement(7727..8278)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.5"
                     /locus_tag="FN307_RS01745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_002404117.1"
                     /transl_table=11
                     /translation="MSQAGLVIIAASFFGQEYSNSYLRTTLLTIPARIKLITTKLFLLT
                     VIVWIIGLFSSLICLGIGIIQFNGSFTLSLILEFLIKVIIAMLSWTQITWITVFLTIIT
                     KSHILPIAIMFSLILGLSQMLFAMTAFAKYLPDLATMNLFFSTHTTTLLNGSQGLLVQS
                     IWSLFLSLISFGLIQYRDVR"
     gene            complement(8454..9239)
                     /locus_tag="FN307_RS01750"
     CDS             complement(8454..9239)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362855.1"
                     /locus_tag="FN307_RS01750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_002362855.1"
                     /transl_table=11
                     /translation="MSFVKVTYSEFSKLINSRGWWIVFGLVIVLQPLLGLLEADQLLSI
                     GLDATPATHPDLLEAMPPLDYFGFDAALFGVLPIVIWGGISGANEYKNHNLRTTMLYSN
                     KRKELFNAKLLTILISTISISFISIFITVAITHVRLGSLGLNPFILSQTTWKFIGYTTL
                     NWILLTVLSFLIGLLFRNMIVPLIFLVPQIYNLGSYLAEKWPWGEYLPVAAGNFIVATP
                     VKSYPHDPAKGTLILLLWIFFSMLIAFYSFTRSDVGGKY"
     gene            complement(9242..9949)
                     /locus_tag="FN307_RS01755"
     CDS             complement(9242..9949)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378542.1"
                     /locus_tag="FN307_RS01755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_002378542.1"
                     /transl_table=11
                     /translation="MKNIVLSNICKQHKKKNILENITFKAKEGRITAFLGPNGAGKSST
                     LRILLGLDLPLSGTATFGKKKYSNFIFPLQIVGSAFDGIGGTPSRKVKTHLKIIAKSNN
                     IPNKRISEVLDLVDLSNKSHAQLGTLSLGEGQRLGIAIALLGDPQYLVLDEPTNGLDPM
                     GIKWFRNFIRRQADQGKTVLLSSHYLSEIEAIADDVVIINKGQIVVTGELHEVMQNIET
                     LEDVFFLLTEGGN"
     gene            complement(10001..12292)
                     /locus_tag="FN307_RS01760"
     CDS             complement(10001..12292)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401909.1"
                     /locus_tag="FN307_RS01760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_002407163.1"
                     /sec_met_domain="PF13471 (E-value: 1.1e-21, bitscore: 73.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIQLFPEQIDPVSFSARFLARLSLILSAPLNWMSPGRIEKILVK
                     LIKNNPPASEKQVKIARNAVCIVSSRCRSQEGCLRRSLAVVIVLWLQRKSVSWCTGYAQ
                     EPFRAHAWIELNECPIGEPVEVQIYSKAICVPHRSNDILRKESYLKKIKQENIERKKKE
                     SEIVNPEDHTPSVNIRSLFALAKGHNWEFICVGILGLISAALTLAQPNLVANLIDQSNT
                     GIKINSSLGILIVVLILSTILTAVQYYLLQIIGEGVVFKARKSLISHLLRLPIHEYDTR
                     SVGDLLSRVSGDSSKLRMALIQVSIALSSGFLVVVGAAIGMILRDSLLFFMALSTVCVS
                     FIGTIIMSKAIQKASFSAQKELGKLSGDIERDLHAIRTIRATNATDKEEEKSKLQAERL
                     RNIGIRLAKIQAFMTPISNMTLQLSGLIVLGIGGYRVSIGLMSVADLIAFALLLYTMIG
                     PIGQVFNAFGGVGESLGAFARIRELLELALESDYDVTPAIPPSSNLITEETAVYFEKIS
                     FGYNKMKFGSDPKEKEDSMILKEVTLRAEKGKRTAIVGPSGAGKSTLLQLIERFYDPDS
                     GKIFVQGKDYRHYSREELRNFITYVEQDAPVISGTLRDNLLLGNSKISDSNCIEVLEEV
                     NLHHLLDRNSKGLDMQVGESGANLSGGERQRLAMARSLLSSAEIVLLDELTSNLDSLNE
                     LGMKKAVDKLKGKKTVIVVAHRLSTVIDSDIIYVLEHGRVVGSGNHNELIDTVPLYREL
                     AKEQFVDREL"
     gene            complement(12292..12540)
                     /locus_tag="FN307_RS01765"
     CDS             complement(12292..12540)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362859.1"
                     /locus_tag="FN307_RS01765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family protein"
                     /protein_id="WP_002362859.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.5e-22,
                     bitscore: 75.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.6e-09, bitscore: 33.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKVKRELKIISQDDGAIVLDKSRGIYFQVNASGVSMLEGLSKGL
                     TIEELALQLETSFSLDKAQAETDVAEFMALLKEMKLA"
     aSDomain        complement(12295..12540)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FN307_RS01765_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="5.30E-24"
                     /identifier="RREFam002.1"
                     /label="FN307_RS01765"
                     /locus_tag="FN307_RS01765"
                     /protein_end="82"
                     /protein_start="0"
                     /score="75.1"
                     /tool="antismash"
                     /translation="MRKVKRELKIISQDDGAIVLDKSRGIYFQVNASGVSMLEGLSKGL
                     TIEELALQLETSFSLDKAQAETDVAEFMALLKEMKLA"
     gene            complement(12598..14382)
                     /locus_tag="FN307_RS01770"
     CDS             complement(12598..14382)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634142.1"
                     /locus_tag="FN307_RS01770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_224567137.1"
                     /sec_met_domain="Asn_synthase (E-value: 4.3e-15, bitscore:
                     52.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLIIVNKSNISISSKKLMFQKRITTDYTNILLVSNTEYSQHTHD
                     QFEIYCISSEYSRIFCNKDQFNYTTTENMLDYLQANISKGVFVLINKEGLFMGGSLFDV
                     SLSWLDSNDELIISDSSANIALFLNLPISKSALALNLIHNLPYYPFQNIPLWEKVNTIQ
                     PFYILKCTTNGILEPIQTWTPPNLENKVESIYSKIRERLLELLSQNTVSYSEISADLSG
                     GVDSATIIYILKALQANVKLYHANADSEWNSDSTWAKLISNDINVIFTSLPSLGSSGKN
                     FEIDRDYSNSVLPDSPLFWADTEGYVESIEHSALTPANATHFTGLGGDELFTPMPANAW
                     SLVRQNKLRSIDLGLRYCLLNRIPISVGTVDLINNNSFKEAVKNEIDKGFGYAKPTRQN
                     SALNWCGPVTVPNWLTKPYRELSYKVLINKLDHTSNSLDSDRSRHQMIESLLFQRHLVT
                     QINNIYGVNGMTWQAPFLDVDIINYSLAIPARYRQDHTVTKSILYNATKGLVSKNIFTR
                     GFKGDYSTSLYKSYKEAVKKHSQQVHQFKLVELGIVDADILISELSMPSALHTRVEAFE
                     RLAAVERWLRVALKKNSK"
     gene            complement(14503..14640)
                     /locus_tag="FN307_RS01775"
     CDS             complement(14503..14640)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002414657.1"
                     /locus_tag="FN307_RS01775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002414657.1"
                     /transl_table=11
                     /translation="MTKQNYSKPSIEKIAGFKESTRGLWTGKFRDVFGGRALFQVVIYY
                     "
     gene            15101..17062
                     /locus_tag="FN307_RS01780"
     CDS             15101..17062
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002410798.1"
                     /locus_tag="FN307_RS01780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_002404120.1"
                     /transl_table=11
                     /translation="MKEKFVYLLSLFVFLVIALLTIKQNDYLYGSQAVTVVPIIVVLIL
                     FCAVIIFVSKDIKKIRYFAVLTFFTSISLAIGLFPYSFVHPVKSLLISFLPYFVYKFFV
                     TFNLISILSVSKKIDQILFIQSIIVSMLLLLNFEKFIWMVSIVIILDIFGCLFLYFKGK
                     DRLTIRTKKEQVFLIRILVLSLFSLIISTSILSGLVLFLIPITVGIILIKRNEISLDKV
                     SIIINLVIHIICIGIFFIINFYFLRLSILDIYFISIFYCLILFILYLKNWYLSSIEVSR
                     IQQRKKDFQKEKIDFVQTISKEKTLSSVSTLISTIFLQHYEINSYLMVWKDQYQPYILS
                     SSGEFSKLILTNKIIAEFERDSNIFHYHNNKYRKFTFFENKQILGWLLIDREKDFDLAS
                     MKHEEIYDLVGVAGKIIIENERLYDIKQESLKIESLSYDEYVNYEYLNMVQNFHKDFSF
                     FIHDNVLQNILALKKLIESMSTENVETKKLVLETFDTLNKTFRDKIFELYPSTIETVPV
                     SQSIRILCDKFNEGQESIFVHFYCPQEMHLKKEEKFHIYRIIQELITNALKHSRATVVC
                     VYLIQRDFYIECIVQDDGTGFDYSKIKLRGFENKHFGILSINQEVNSLNGKMRVSSVNP
                     HGTKFTITLPIAKEDIDS"
     gene            17059..17652
                     /locus_tag="FN307_RS01785"
     CDS             17059..17652
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362865.1"
                     /locus_tag="FN307_RS01785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator"
                     /protein_id="WP_002362865.1"
                     /transl_table=11
                     /translation="MKVYLLDDHALFSKSLEIAFQPMDVSITSFTNPEFFLNKLKNEQP
                     DLALLDIHIGELSGFEISKEIIGKFPNQKIVFLSGFDLIEYKNEAIKSGAWGLLNKNVT
                     IEELYDDLQKIHHGTDLLPKCQSTLDVLSKREKEILKCAAEGFKQQEIAEQLHISRRTV
                     NNHLVSINNKLEVNSTISAIIQAIELGIIRVKGY"
     gene            complement(17703..>18274)
                     /locus_tag="FN307_RS01790"
                     /pseudo=""
     CDS             complement(17703..>18274)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002415745.1"
                     /locus_tag="FN307_RS01790"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="CHAP domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="IQFSKTQADGKTVTYTNPIAINIGYDYRYAYGNMFYAQIVKQYIT
                     SISNNNSQGNSAIVKAALKELNEGIHKGGTKYWQWYGFNGRVEWCAIFVSYNAEKAGVK
                     MEHFAYCPTGIENFKANNQWFRKGSLPKNGNIIFFDWDGDSISYYVGIVEKVENEVVYT
                     IEENSGNKIAKLSYEKIALISWVMVFR"
     gene            complement(18225..18557)
                     /locus_tag="FN307_RS14740"
     CDS             complement(18225..18557)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024254.5"
                     /locus_tag="FN307_RS14740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_002362869.1"
                     /transl_table=11
                     /translation="MLLAFIFVLFEFVHFFPFQCVQLFYSTIILNDITDKKANSPHIAI
                     TGPTVNGKSYLAKFIFFLSVLMNGKGLYVDPKSEFFNRIMEVINHPLYYDSILKNSSRW
                     KNSHLH"
     misc_feature    18702..18715
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.62"
                     /tool="antismash"
     gene            complement(19163..19765)
                     /locus_tag="FN307_RS01805"
     CDS             complement(19163..19765)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002413059.1"
                     /locus_tag="FN307_RS01805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YitT family protein"
                     /protein_id="WP_002393123.1"
                     /transl_table=11
                     /translation="MKLVKNVLLILIGLVIIGIGASTLRVAGLGVDPFTAMNIGLSSMF
                     GMQLGIFQIIVNAFILFYVYLKNKKAIGLGTILNMLLVGILIQQISTWLQPYADSLGGS
                     TIGKLLSLFVGVLIFTFGCALYMATDQGESPYDAIAPTICQQINKPYASVRKAQDLLVL
                     LIGFIAGGPIGIGTIICAFGAGPLISFWNKLLQPLVK"
     gene            complement(19850..20629)
                     /locus_tag="FN307_RS01810"
     CDS             complement(19850..20629)
                     /NRPS_PKS="Domain: PKS_KR (50-167). E-value: 6.9e-07.
                     Score: 21.3. Matches aSDomain:
                     nrpspksdomains_FN307_RS01810_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376895.1"
                     /locus_tag="FN307_RS01810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_010709706.1"
                     /sec_met_domain="adh_short (E-value: 3.5e-30, bitscore:
                     101.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.7e-31, bitscore:
                     104.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYGELHGKVAVVTGAATGLGLFITLRYILEGMNVVADYVGELPKE
                     FEDVQAKHADRVKFVKADVSNEEDIKALAETALKEFGHVDIWVNNAGVEASFPTIDMPL
                     KEWQRVIDVNLNGVFLGSREALRIFRDQKIKGSIINMSSVHQKIPWPTFAHYAASKGAT
                     EMFTKTIALEYAEYGIRANCIAPGAINTPINAEKFSDPEQLKQTTSMVPMGIIGKPNQV
                     AAAAAWLASDESSYVTGTTLFVDGGMSLYPSFQHGAG"
     aSDomain        complement(20129..20479)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FN307_RS01810_PKS_KR.1"
                     /evalue="6.90E-07"
                     /label="FN307_RS01810_PKS_KR.1"
                     /locus_tag="FN307_RS01810"
                     /protein_end="167"
                     /protein_start="50"
                     /score="21.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="AKHADRVKFVKADVSNEEDIKALAETALKEFGHVDIWVNNAGVEA
                     SFPTIDMPLKEWQRVIDVNLNGVFLGSREALRIFRDQKIKGSIINMSSVHQKIPWPTFA
                     HYAASKGATEMFT"
     misc_feature    complement(20835..20850)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.46"
                     /tool="antismash"
     gene            21045..22313
                     /gene="rseP"
                     /locus_tag="FN307_RS01815"
     CDS             21045..22313
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="rseP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359768.1"
                     /locus_tag="FN307_RS01815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RIP metalloprotease RseP"
                     /protein_id="WP_002359768.1"
                     /sec_met_domain="Peptidase_M50 (E-value: 7.4e-84, bitscore:
                     277.2, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTIITFIIVFGILVLVHEFGHFYFAKRAGILVREFAIGMGPKIF
                     AHRGKDGTTYTIRLLPIGGYVRMAGMGEDMTEITPGMPLSVELNAVGNVVKINTSKKVQ
                     LPHSIPMEVIDFDLEKELFIKGYVNGNEEEETVYKVDHDATIIESDGTEVRIAPLDVQF
                     QSAKLSQRILTNFAGPMNNFILGFILFTLAVFLQGGVTDLNTNQIGQVIPNGPAAEAGL
                     KENDKVLSINNQKIKKYEDFTTIVQKNPEKPLTFVVERNGKEEQLTVTPEKQKVEKQTI
                     GKVGVYPYMKTDLPSKLMGGIQDTLNSTTQIFKALGSLFTGFSLNKLGGPVMMFKLSEE
                     ASNAGVSTVVFLMAMLSMNLGIINLLPIPALDGGKIVLNIIEGVRGKPISPEKEGIITL
                     IGFGFVMVLMVLVTWNDIQRFFF"
     misc_feature    complement(21046..21060)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.91"
                     /tool="antismash"
     gene            22385..24103
                     /locus_tag="FN307_RS01820"
     CDS             22385..24103
                     /EC_number="6.1.1.15"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /GO_function="GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /GO_process="GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359769.1"
                     /locus_tag="FN307_RS01820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="proline--tRNA ligase"
                     /protein_id="WP_002359769.1"
                     /transl_table=11
                     /translation="MKQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVAAGIYSYLPL
                     ANRVLEKLKTIMREEFEKIDAVEMLMPALLPAELWKESGRYETYGPNLYRLKDRNDRDY
                     ILGPTHEETFTELIRDEINSYKRLPLNLYQIQTKYRDEKRPRSGLLRGREFIMKDGYSF
                     HADEASLDQSYRDYEKAYSRIFERCGLEFRAIIGDGGAMGGKDSKEFMAISEIGEDTIC
                     YSTESDYAANLEMATSLYTPKKSHETQLDLEKIATPEVGTIAEVANFFEVEPQRIIKSV
                     LFIADEEPVMVLVRGDHDVNDVKLKNFLGADFLDEATEEDARRVLGAGFGSIGPVNVSE
                     DVKIYADLAVQDLANAIVGANEDGYHLTNVNPDRDFQPISYEDLRFVQEGDPSPDGNGV
                     LAFTKGIEIGHIFKLGTRYSDAMGATVLDENGREKSVIMGCYGIGVSRLLSAIVEQNAD
                     ERGINWPTGIAPFDLHVVQMNVKDEYQTKLSQEVEAMMTEAGYEVLVDDRNERAGVKFA
                     DADLIGCPIRITVGKKAVDGVVEVKIKRTGEMLEVRKEELESTLSILMNTTSEVE"
     misc_feature    24238..24251
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.16"
                     /tool="antismash"
ORIGIN
        1 tcgtggttgg cggcggaaac atttggcgtg gacaaattgg tgctcaaatg ggcatggaac
       61 gtgcacaagc tgattatatg ggcatgttag ctactgtgat gaatgcctta gcattgcaag
      121 atacattaga aaatcttggt gtgcctacac gtgttcaaac atcaattgaa atgcgtcaaa
      181 ttgcagaacc atacattcgt cgtcgtgcag aacgtcattt agaaaaaggc cgcgttgtta
      241 tttttgccgg aggaacagga aatccttact tctcgacaga tacaacggct gcgttacgag
      301 ctgcagaagt agatgcggac gtcatcttaa tggcgaagaa caatgttgat ggtgtttatt
      361 ctgcggatcc acgtgtggat gaaacagcga caaaatttga agaactaaca catttagatg
      421 ttatttctaa agggctgcaa gtaatggatt caacagctag ctcattaagt atggataacg
      481 atattccttt agttgtcttt aacctaaatg aagcaggaaa tatccgtcgt gccatccttg
      541 gtgaaaatat cggaacaact gtaaggggga aataaagaat gtctaaagaa gttttagcaa
      601 cagccaaaga aaaaatgaca aaagcggaag aaagcttacg ccgtgaatta ggtcaaattc
      661 gtgctggtcg tgcgaacgca agtctattag accgtattca agtagaatat tatggtgcac
      721 caacaccagt taaccaatta gcaagtatca atatcccaga agcacgtgta ttaatgatta
      781 caccgtttga caaaaattct atcgctgaca ttgaaaaagc tattcaaatg agtgatatcg
      841 gcattagccc aaccaatgat ggaaatgtca tccgtttagt gattccacaa ttaacggaag
      901 aacgtcggaa agaattagcc aaagacgtga aaaaagaagc ggaaaactca aaagttgctg
      961 tccgtaacgt tcgtcgtgat gcaatggatg agttgaaaaa agctcaaaaa aatggcgaca
     1021 tcactgaaga tgaattacgt tcatttgaaa aagatgttca aaaattaaca gatgatagca
     1081 tcaaaaatat cgatgcgatt actgctgaaa aagaacaaga acttttagaa gtataaaacc
     1141 aatcactaat aaaaattatt gaatccagag aagcaaatgc tctggatttt tttgtataga
     1201 tgaggaaggc gtatctcaac gctctctttg cgaaagtcat tctaaagtaa ttatttaaga
     1261 aaacgctttc ttggataatt ttttttattc taccagaatt tttttctttg tgtagggagg
     1321 atcacttaaa aatatagaga aactttgaaa tatcagcctt ttaaaatttt tcttcacaaa
     1381 ttgaatccta aaatttgatg ataagagttg ttatttttag caattgtaat ttgcgattca
     1441 ttctcaatta ggctaaaatg agtgagaacg gaaaaacgat taaaacaagt tggagggaat
     1501 tgtacatgtc tgtgttagaa atcaaaaatt tacacgtatc aattgaagat aaaaagattc
     1561 taaaaggggt cgatttaaca attaatactg gagaaatcca tgcaattatg ggacctaatg
     1621 ggactggtaa atctacttta tcagcagcaa ttatgggaaa tcccaactat gaagtcacag
     1681 aaggagaaat tctatttgac ggcgtcaacg ttttagattt agaagtagac gaacgcgctc
     1741 gcctaggctt attcttagca atgcaatacc caagtgaaat tccagggatt accaatgctg
     1801 aattcatgcg tgcagcaatc aatgcaaaac gtgacgaaga caacaagatg tcagtcatgc
     1861 agttcttaaa aaaattagat agcaaaatgg aattattaaa tatgcctgaa gaaatggctg
     1921 agcgttactt aaacgaaggt ttttctggcg gcgagaaaaa acgaaatgaa attttacaat
     1981 tattgatgtt agagcctacg tttgccattt tagatgaaat tgattcaggc ttagatatcg
     2041 atgcgttaaa agttgtttct aaaggggtta atgaaatgcg cggcgagaac tttggagcgt
     2101 taattattac ccattatcaa cgcttattga actatatcac gccagatgtt gttcatatca
     2161 tgatggaagg ccgcgttgtg aaaaccggtg gggctgattt ggcaaaacgt ttagaaacag
     2221 aaggctatgc tggtatcagc caagaattag gtattgatta caaagaagaa gcgtaaggag
     2281 gacaagataa atgaaaaaag taaatctaat ggattatctt gacgaagtca ccgctttttc
     2341 actagaacat gaagaaccag cttggatgac tgaattgcga acaacggctt taaaaaacgc
     2401 tgacgaaagt gagttaccac atattgatcg tgtgaaattt catcgttggc ctttattaaa
     2461 tgttcacatg gaaagttatg tgccttctga aggaaatgtc gcaagttttg atcaaatgaa
     2521 agacaatcct ttaattgttc aacaaggatc ttttcatgct tttgagcaat tgccagcctc
     2581 attagcggaa caaggggtaa tttttacaga catttttact gctttacaag agcacccaga
     2641 attagttaaa gaatactata tgactaaagc cgtattacca gaagaagata agctgacagc
     2701 agctcatgca gctttcatga atagtggcgt tttcttatac gttcctaaaa acgtagtgat
     2761 tgaagagcca attgaatctt tgtttattca ggattcagat agcaaccaac ctttctttaa
     2821 acatgtttta atcgttgcag ataatcatag tgaattcagt tatttagaac gttttcaatc
     2881 aactggtcat cacgcagaga aagcttctgg aaatatcgtt gtggaagtga ttgcgaaaga
     2941 tggcgcaaaa gttaaatact cagccgtgga tcaattaggg caaactgtaa cgacttatat
     3001 gaatcgtcgt ggctatatta tgcgggatgc ctctgttgat tgggctctag gcgtcatgaa
     3061 tgatggcgat gttgtggctg attttgattc tgatttagtt ggcgaaggcg ctcattcaga
     3121 agttaaagtt gttgcaatta gtgcaggtaa acaaacacaa ggcatcgaca cacgagtgac
     3181 aaacaaagcg ccacattcaa ttggtcatat tttacaacat ggagttattc gtgaacgtgg
     3241 tactttaacg tttaacggaa ttggccacat tttaaaagga gcaaaaggag ccgacgcaca
     3301 gcaagaaagt cgtgttttaa tgctgtctga taaagctcgt ggtgatgcca atccaattct
     3361 tttaattgat gaaaatgaag tgactgccgg acacgcagcc agcgttggtc gagtagatcc
     3421 agaagaaatg tattatttaa tgagccgcgg cttgcgtaaa gaagaagcgg aacgtttggt
     3481 gattcgtggc ttcctaggtt ctgtcattac agcaattcca gttaaagaag tacaaaatga
     3541 atttgtagaa gtaattgaag ggaagttaaa cgcatgatgg atgcagcaac cattcgtcaa
     3601 tcgtttccta ttttatttca agaagttaat gatgaaccgc tagtttattt agacaatgct
     3661 gcaacaaccc aaaaaccaac ggcagtgtta gatattttac gacattatta tgaaaccgat
     3721 aatgccaatg ttcatcgtgg ggtgcacacg ttagccgaac gagcaacgaa ggactatgaa
     3781 gcctcccgcg aaaaggttcg ccaatttatc catgccaaag aaacagcgga agttttattt
     3841 acacgaggaa caacaaccag tttgaattgg attgccaaaa gttatggtga cttggcagtt
     3901 acagccgggg atgaaatcgt catatcttac atggaacatc attcaaacat tattccctgg
     3961 caacaattag cccaacgtac aggagccatt ttgaagtata tagacgtcac tgaagacggc
     4021 tttttagaca tggcaagtgc acgtcaacaa attacagaaa aaacgaaaat tgtttcgatt
     4081 gctcatgttt caaatgtgtt aggggtcatt aatccaatcg aagaattaac acaattagct
     4141 catcaaaatg gcgctgtgat ggtggtagac ggcgcgcaag cagttcctca tatgcctgtg
     4201 gacgttcaag ccatcgatgc tgatttttat gcatttagtg gtcacaaaat gtgtggacca
     4261 actggaattg gtgtccttta tggcaaacgt catttattgg aacaaatgga acctgtggaa
     4321 tttggtggcg aaatgattga ctttgttcat cttcaagaaa gtacttggaa agagcttcca
     4381 tggaaatttg aagctggcac acctaatatt gctggggcaa ttgccttagg tgccgccatt
     4441 gattatttaa cagaaattgg tttagaggcc attcatcaac atgaagcagc ccttgttcac
     4501 tatgttttgc cgaagttgca agctatcgag ggcttgacga tttatggtcc acagaatcca
     4561 aaagaccaca caggtgtgat tgcttttaat attgaaggtt tacatccaca tgatgtggct
     4621 acagcgttag atatggaagg ggtcgctgtc agagcgggtc accattgcgc gcaaccgcta
     4681 ttaaactatt tgagcgtgcc agcaaccgca cgggcaagtt tttatttata caataccaaa
     4741 gaagacgcag atcgcttagt tgaagcgatt aaagcgacaa aggagttttt ccagcatggc
     4801 actttctaaa ttagataact tatatcgcca agtcattttg gaccattcta gccacccaca
     4861 tcaccacgga acgctagatg cgtctagcca aacaattgaa ctgaataatc ctacttgtgg
     4921 agatgtgatt gaactggatg tggccattga agacggtgtg attaaagata tcgcctttca
     4981 aggaagtggc tgttcaatca gtacagcaag tgctagtatg atgactgatg cggtcttagg
     5041 aaaaacaatc gccgaagcaa cggccttagc agaggatttc tctcaacttg ttcaaggaaa
     5101 tgaagtggcc gaagatgaaa aattaggcga tgcagcaatg ttaagcggcg tagctaaatt
     5161 tccagctcgg attaaatgtg caaccctggc ttggaaagcc ttagagcagg ctgttgctaa
     5221 taacggtcaa ggcgaagccg gtcatttaca ttgtgaaaaa taaagaaagg gtgacgacga
     5281 attgagtaca gtacctgaat tagaagaata taaatttggc tttcacgacg atgtggaacc
     5341 agtctttagt accggagacg gcctaacaga agacgtcgtt cgcgaaattt ctcgcgtgaa
     5401 aggcgaacca gaatggatgc ttgacttccg tttaaaatcg ttagaacaat tcaataaaat
     5461 gcccatgcaa gaatggggtc cagacctgtc agatattgac tttagtaaaa ttaaatatta
     5521 ccaaaaaccg agtgacaaac ccgcacgcga ttgggatgat gtacctgata aaatcaaaga
     5581 aacctttgaa aaaattggga ttcccgaagc tgagcgtgct tatctagctg gggcttctgc
     5641 tcaatatgaa tcagaagttg tttaccacaa catgaaagaa gaatttgaaa aattaggcat
     5701 catttttaca gatactgact ctgctttaaa agaatatcct gacctattca aagagtattt
     5761 ttcaaaactt gtgccgccga cagataataa actggccgct ttaaactcag ctgtttggtc
     5821 aggtggaacc tttatttatg taccaaaagg cgttcgagtt gatgtaccat tacaaacata
     5881 tttccgaatc aacgctgaaa ataccggcca atttgaacgg accttgatta ttgtcgatga
     5941 aggggccagc gttcactatg tcgaaggctg tacggcaccc acgtattcaa gtaacagctt
     6001 gcatgcggcc atcgtagaaa ttttcactag aaaagatgct tattgtcgtt ataccactat
     6061 tcaaaactgg tcagataacg tctacaactt agtaaccaaa cgtgctaaag cttacgaagg
     6121 tgccactgtc gaatggattg atgggaacct aggagctaaa acaaccatga aatacccaag
     6181 cgtttactta gatggcaaag gtgcccgtgg cacgatgtta tcgattgcct ttgctggcgc
     6241 taaccaaatc caagatactg gggccaaaat gattcacaat gcgccgaata cctctagctc
     6301 aattgtttca aaatcaattg ctaaagatgg cggcgaagtt aactaccgtg gtcaagtgac
     6361 ttttggcaaa gacagcgcag gctcgatttc ccacatcgaa tgcgacacga ttatcatgga
     6421 cgaaaaatca aaatcagata cgattccgtt taatgaaatc cataacagcc aagtgtcctt
     6481 agaacacgaa gccaaagttt caaaaatttc tgaagaacaa ttatattatc taatgagtcg
     6541 cggcttatct gaagccgaag cgacagaaat gattgttatg ggctttgttg aaccatttac
     6601 gaaagaatta ccgatggaat atgcggttga gttgaatcgg ttgattagtt atgagatgga
     6661 aggtagtgtg gggtaaaacc tttttcagcg ctagaaatgt tgatttatca atgtttctgg
     6721 tgcttctttt tttcaaaaaa gcaaactaac tacaatttct tttagaaaag atatttttcc
     6781 ttttcaataa actgagcgaa ttggtcagcg ctacgctcct tacgttcggg gtagaagtag
     6841 ttatatactt gtcgagtcat ctttgaatct ttatggccga cacggtacat aatatcttct
     6901 tttttacaac atatttttct agcagaaatc tcttttcttt aatattaagt tgtttgattg
     6961 cttatataag caattcatct tcaaaataag tttcaaagtt tttcaagtca agtgatgaca
     7021 tattgataat attaaaatag ttatatgtgt aagaagaatc gagcgtgata tcgtgaaaat
     7081 aggtaaagag tagtctagtg gagtagttcc tcttttttta taatagttgt ttgcatgata
     7141 gtgtagtaca cctatatgaa tgtatttttt tagtttgtta tcgcttggag tattgtccat
     7201 gtaaactacc tcctatatct atgtgacttt tcctgatgtc tatactgcca aaaactttta
     7261 tgaacttttt taacaggtaa gctattatcg tctggcattt ttggtaaaat attatttact
     7321 agattgttat aacctaaatt gaaatgtaga tttttttgtg attacagaat aaatttgtga
     7381 agcattcatc ggtatgccag aagttttaaa aatgtagcag atatttttag aaataatgtc
     7441 gtgagaatag aagtagtctt tattttttga tcattaaatt ttgcgtaatc aattttttct
     7501 atttggttta atcgtttttc gattgtctca caaagactgg taattgcttt tctctcatag
     7561 attaattcaa ctataagttt cataagcgtt tttttcttct aataaattca aaataatcac
     7621 ttctttatta ataagaggtt ttaaagccat tcaataacaa caaaaaacta tcaattgatt
     7681 tttgatagtt tctatatagt agtatttaag gaaagtgaag aggtagtcat cgaacatcac
     7741 gatattgaat caatccaaat gaaattagac taagaaataa ggaccagata ctttgaacta
     7801 ataaaccctg agaaccattt aataaagtag ttgtatgggt tgaaaaaaaa agattcatgg
     7861 ttgctaaatc gggtaagtat tttgcaaatg cagtcattgc gaataacatt tgacttaatc
     7921 caagaataag agagaacatt attgcaatcg gtaaaatatg tgatttggta atgatggtca
     7981 aaaagactgt aatccaagtt atttgcgtcc aacttaacat tgcaataatc actttaatca
     8041 aaaattcaag aattaaagag agagtaaaag agccgttaaa ttggataata ccaattccta
     8101 agcaaattaa actggagaat aaaccaataa tccatacgat aactgttaga agaaatagtt
     8161 tagtagtaat gagttttatt cgagcaggta tcgttagtaa agttgtacgt aaatatgaat
     8221 ttgaatattc ttgaccgaag aaactagcag ctattataac aagtcccgct tgactcaaaa
     8281 aaaattacgt atactcatgg ataatatctc attggttacc aaaggttgat catttccaat
     8341 tccagaaaaa aataatatta caggagctac taaaatggtt ccgactgtgc cgaataagca
     8401 ccaattataa gagaaaaatt tgattatttc actttgaaga atatttttaa ccatcaatat
     8461 tttcctccca cgtcgctacg agtaaacgaa tagaatgcta ttaacataga aaaaaatatc
     8521 catagaagaa gtatcaatgt accttttgct ggatcatgag gataagattt aaccggagta
     8581 gcaacaataa aatttcctgc tgctacgggt agatattccc cccagggcca tttctctgct
     8641 agataacttc caagattata gatttgagga actagaaata tcaacggaac aatcatattt
     8701 ctaaaaagta agccaatcaa aaaggataaa accgttaata atatccaatt taatgtagtg
     8761 tagccaataa acttccaagt agtttgactt aaaatgaatg gattcaatcc taaactacct
     8821 aatctaacat gtgtaatcgc aacggtaata aatattgaaa tgaatgaaat tgatatagta
     8881 gaaatcaaaa tagttagtag tttggcatta aaaagttctt tacgcttatt actatataac
     8941 atggttgtac gtaaattatg atttttatat tcattagctc cgctaattcc gccccatatt
     9001 acaattggaa gtactccaaa tagagcggca tcaaaaccaa aataatctaa tggaggcata
     9061 gcttctaata aatctggatg tgttgcagga gttgcatcta atcctatgga aagtaattga
     9121 tccgcttcta ataatccaag taagggttga agcacgatta ctaatccaaa aactatccac
     9181 catccacgac tatttatcag tttagaaaat tcggaataag ttactttaac aaaactcatg
     9241 attaatttcc tccctcagta agtagaaaga atacatcttc taatgtttca atattttgca
     9301 tcacttcatg aagttcacca gtaacaacaa tctgaccttt gttaatgata acaacgtcat
     9361 ccgcaatagc ttcgatttca gaaaggtagt gtgaggagag taatactgtt tttccttgat
     9421 cagcttgtct acgaataaaa tttctaaacc attttattcc catgggatct aaaccatttg
     9481 ttggttcatc aagaaccaga tattggggat ctcctagcag agcaatagca atacctaatc
     9541 tttgcccttc acctaaagat aaggttccaa gttgtgcatg acttttattt gataggtcga
     9601 caagatctaa gacttctgaa atacgtttat tcgggatgtt gttacttttt gcaatgattt
     9661 tcagatgtgt tttaactttt cttgatggag ttccgccaat cccatcaaat gccgatccga
     9721 caatttgtaa tggaaagatg aaattactat actttttttt accgaaagtg gctgttcctg
     9781 ataaaggcag gtctaaaccg agaagtattc taagtgtaga gctctttcca gctccgttag
     9841 gtccaagaaa agctgttatg cgtccttctt tagccttaaa agttatattt tctagtatat
     9901 ttttcttttt atgttgttta catatatttg aaaggacaat atttttcaat agtatggctc
     9961 ctttaaattt ttttatttaa tttgttctta aattaaaaat ttacagttct ctatccacaa
    10021 attgttcttt cgctaattct cgataaagtg gaactgtatc aattagctca ttatgatttc
    10081 ctgaaccgac aactctacca tgttcaagga cataaatgat atcagaatca attactgtgg
    10141 atagacgatg tgctacaacg ataactgttt ttttcccttt taatttatcc actgcctttt
    10201 tcattcctaa ttcatttaag ctgtccaagt tagaggttaa ttcgtcaagt aacacaattt
    10261 ctgcagatga taaaagagag cgtgccatag ccaaacgttg tctttctcca ccagagaggt
    10321 ttgcaccaga ttctccaacc tgcatatcaa gtcctttaga atttctatct aataaatgat
    10381 gaagattgac ttcttccaat acttcgatgc agtttgaatc agatatttta gaatttccta
    10441 aaagtaggtt gtcgcgtagt gtcccagata taacaggagc gtcttgttca acataagtga
    10501 tgaagttccg aagctcctct ctgctataat gcctataatc ctttccttga acgaatatct
    10561 tgccactgtc aggatcataa aatctttcaa ttaattgaag caatgtgctt tttcctgcgc
    10621 ctgagggacc tacaattgca gttctttttc ccttttctgc acgtaacgtt acttctttga
    10681 gaatcatgct atcttctttt tccttaggat cagaaccaaa tttcatttta ttatatccaa
    10741 agctgatttt ttcaaaatag actgcagttt cctcagttat taaatttgaa ctggggggaa
    10801 tagcgggagt gacatcatag tcactttcta atgcaagttc taataattcg cgaattctag
    10861 caaaagcacc gagtgattcg ccaacgcccc cgaaggcatt gaaaacttgt cctatcggac
    10921 caatcattgt atagagtagc aaagcgaatg caattaagtc agcaacagac attaaaccaa
    10981 tagacacacg gtatccacct attcccagta caattagacc agatagttgc agagtcatat
    11041 tagaaatagg agtcatgaat gcttgtattt tagctaatct tattccaata ttacgcaatc
    11101 gttctgcttg caatttagat ttttcttcct ccttgtctgt tgcgtttgtt gcacgaattg
    11161 ttctgatagc atgtaaatca cgttcgatat ctccactcaa ttttcccaac tctttttgtg
    11221 cagaaaaact agccttttgt atagctttac tcataatgat ggttccaata aaagatacac
    11281 aaactgttga aagagccata aaaaatagca aggaatctct caaaatcatc ccgatagctg
    11341 ccccaacaac aactaaaaaa ccactactga gcgcaatact cacttgtatt aaagccattc
    11401 tcaatttaga agagtcacca ctaaccctgc ttagtaaatc acctacactt cttgtatcgt
    11461 actcgtggat tggcaatctt aataaatgac taattaaact ttttcgcgct ttaaaaacga
    11521 ccccttcacc aattatttgt agcagataat attgaacagc cgttaaaatc gtagatagta
    11581 tcaatactac aatgagaatt cctaaacttg aattaatctt aattcctgta tttgattgat
    11641 caattaaatt agcaacaagg ttaggttgag cgagggttaa agctgcactg attaatccta
    11701 atattccaac gcaaatgaat tcccaattat gcccttttgc taatgcaaac agggatctaa
    11761 tatttactga gggcgtatgg tcttcaggat taacaatttc ggactccttc tttttacgtt
    11821 ctatattttc ttgttttatt tttttcaaat acgattcctt tctgagaata tcatttgaac
    11881 ggtgtggaac acatattgct ttagaatata tttgaacttc tacgggttct ccaatagggc
    11941 attcattcaa ttctatccat gcatgtgctc taaatggctc ttgtgcatac ccagtacacc
    12001 aacttactga tttacgttgt agccatagta ctattacaac agcaagcgat cgtctaaggc
    12061 atccttcttg acttctacat ctactactta cgatacacac tgcgtttcgc gcaattttta
    12121 cctgtttttc tgatgcggga ggattgtttt ttattagctt caccaatatt ttttcaattc
    12181 tcccagggga catccaatta agcggtgcag atagtattaa actcaaacga gccagaaatc
    12241 ttgcactaaa agataccgga tctatttgtt ctggaaaaag ttggatattc attatgcaag
    12301 tttcatctcc ttcaaaagag ccataaactc ggcaacatct gtttccgctt gagctttatc
    12361 tagagaaaat gaagtttcca attgtagtgc taactcttct atcgtcaatc ctttactcaa
    12421 accttctaac atagaaactc cagaagcatt tacttggaaa taaattcctc tacttttatc
    12481 caaaacaatt gcaccatcat cttggctaat aattttcaac tctcttttta cttttctcat
    12541 taatattact cctccttttt agaaaataac tacaactagg taagcagcaa cttcctttta
    12601 ttttgagttc ttttttaaag ctacacgaag ccagcgttca acagctgcta atctctcaaa
    12661 ggcttcaact ctagtatgta gagcagaagg cattgataat tcagaaatta gtatatctgc
    12721 atctacaatt cctaattcaa ctaatttgaa ttggtgcact tgctgggaat gcttttttac
    12781 ggcttctttg taacttttat acaaacttgt ggaatagtct cctttaaatc cacgtgtaaa
    12841 aatatttttt gaaacaagtc ctttagtggc attatataaa atcgattttg ttacagtgtg
    12901 atcttgtctg taacgagctg gtatagctaa cgagtaatta ataatatcga catctaaaaa
    12961 gggagcttgc caagtcatac cattaacacc atatatgttg ttaatctgag ttaccaaatg
    13021 tctttgaaaa agtagagact cgatcatttg gtgtcgagaa cgatcggaat ctaaagaatt
    13081 cgatgtgtga tctaatttat ttattagaac tttataactt aattctcggt aaggcttcgt
    13141 aagccaatta ggtaccgtga ctggaccgca ccagttgagt gcggagtttt gacgagttgg
    13201 tttagcataa ccaaatcctt tgtctatttc attttttaca gcttccttaa aggaattatt
    13261 atttattaga tctactgtcc caactgaaat aggaatccga tttagtaaac aatatcgtaa
    13321 gcctaagtct atactgcgta atttattttg tcgtacaaga gaccatgcgt tagcaggcat
    13381 aggagtgaat aattcatccc cgccaagacc tgtaaaatga gtggcattgg cgggagttaa
    13441 tgctgaatgt tctatggatt caacatatcc ctctgtatct gcccaaaata atggagaatc
    13501 tggtaacact gagtttgagt aatctctatc aatttcaaaa ttttttcccg agctacctaa
    13561 agaaggtaat gaagtaaata tgacgttgat atcgtttgag attaattttg cccatgtaga
    13621 atcgctattc cattcactat cagcatttgc gtgataaagt ttaacattag cttgaagtgc
    13681 ttttaagata taaataattg ttgctgaatc aactccaccc gaaaggtcag cggatatctc
    13741 agagtaacta actgtatttt gactaagcaa ttctagaagc cgctctcgta tttttgaata
    13801 aatagattcg actttgtttt ctaagtttgg aggtgtccaa gtttgtatgg gttctaagat
    13861 tccatttgtt gtacatttca aaatatagaa tggttggatc gtgtttactt tttcccataa
    13921 gggaatattt tggaatgggt agtatggtaa attatgaatt agatttaatg caagagccga
    13981 tttagaaatt ggtaaattaa gaaataatgc gatatttgct gatgaatcac taatgattag
    14041 ttcatcattt gagtccaacc atgaaagaga aacatcaaat aatgatcctc ccataaatag
    14101 cccttcttta tttattaaaa caaatacgcc tttagaaata tttgcttgaa gataatctaa
    14161 catgttttct gtagtagtgt agttaaattg gtctttattg caaaatattc ttgaatattc
    14221 agaagaaata cagtaaattt caaattgatc gtgtgtatgt tgagagtact cggtattgga
    14281 taccagcagt atattagtgt agtctgtagt aatacgtttt tgaaacatca atttttttga
    14341 ggatatagag atatttgatt tgtttacaat aattagaagc acctccctaa ataaagacta
    14401 tgcggattac taaaaaggtc atcgaattat gtaattcgat gaccaatggc ataattatgt
    14461 aattcgatga ccgctagcat aattatttcc catttttctg tcctagtaat aaattacaac
    14521 ttggaaaaga gcgcgtccac caaatacatc tctaaattta cctgtccaaa gaccacgagt
    14581 agattcttta aaacctgcaa ttttttcaat tgatggttta ctgtaatttt gctttgtcat
    14641 agagttcacc tccttcatag ttggtgtata ctaaattttc taattcaagt aaattagaaa
    14701 atagttacct tgattactta gtactgaaaa atgagtatag gaaattcttg acatctatat
    14761 tttagttaaa caatagaaca aaacagctag aatcaggaaa taaattactc ttaattcgtt
    14821 gtttttaagg ttaagtagct tttttctatt caacttatat attaatcata caaaaaaagg
    14881 gattatttgt aatgagtata ttgtgcaatt atttaagaaa gagtaagatg aagatatcat
    14941 taaaaaatac acagagtgga gtatgaataa aatctgtgtt gtttaataca ttagtgggat
    15001 attagaaaat tttattcaaa ctataaattc aaaattagta tctttaaaaa aacgaagaac
    15061 tgtagaatat tcaaggaata cttagattgg agaaaagtgt atgaaagaaa aatttgttta
    15121 tttgttatcc ttatttgtat tcttagtgat agctctactt actattaagc agaatgacta
    15181 tttgtatgga tcgcaagcag taactgttgt accgattatt gttgtactta ttcttttttg
    15241 cgcagttatt atttttgtct ctaaagatat taaaaagatt agatacttcg ctgtacttac
    15301 tttttttact tccatttcct tagcaatagg attatttcct tattcttttg tgcatcctgt
    15361 caaatccctg ctaatttcat ttttacctta ctttgtttat aagttttttg tcacttttaa
    15421 cttaatttcg attttatctg tttctaaaaa aattgatcaa attttattta tacaatctat
    15481 tattgtatcc atgttactgc ttcttaattt tgaaaaattc atatggatgg tgagtatagt
    15541 aatcattttg gatatttttg gttgtttatt tttatatttt aaaggaaaag atcgactaac
    15601 cattcgaaca aaaaaagaac aagtttttct aattcgaata ctagttttat cgctattttc
    15661 gttaattatt tctacttcta ttttaagtgg gttggttctt tttcttatcc caatcacagt
    15721 cggaattatt ttaataaaac gtaatgaaat tagcttagat aaagtatcaa ttattataaa
    15781 tttagttatc catattattt gtataggaat cttcttcatt attaattttt attttcttcg
    15841 attatcaata cttgatatct attttatttc tattttttat tgtctgattt tgtttatcct
    15901 ttatttgaag aattggtatt tgagtagtat tgaggtgagc cgaattcaac aaagaaagaa
    15961 agatttccaa aaagaaaaga tcgattttgt acaaactatc agtaaagaaa agactttgtc
    16021 ttcagtaagt actttaatta gtacaatctt tttgcaacat tacgaaataa atagttattt
    16081 aatggtttgg aaagatcaat accaaccata tattttgtct agctcaggag aattttctaa
    16141 actgatttta acgaataaaa ttattgctga atttgaacgc gactctaaca tattccatta
    16201 tcacaacaat aaatatagaa aattcacttt ttttgagaat aaacaaattt taggttggtt
    16261 actcatagat agagaaaaag actttgactt ggcgagtatg aaacatgaag aaatatatga
    16321 tttagttggt gttgctggta aaataattat tgaaaatgaa cgcttatatg atattaaaca
    16381 agaatcatta aaaatagaaa gtttatctta tgatgaatac gtgaattatg aatatttaaa
    16441 catggtgcaa aattttcata aagatttttc attttttatt catgacaatg ttttacaaaa
    16501 tattttggct ttaaaaaaac taatcgaatc tatgtctact gaaaatgtag aaacaaagaa
    16561 attagtatta gaaacttttg atactttaaa taaaactttt agagacaaga tatttgaatt
    16621 atatccttcg acgattgaaa cagtgcctgt gtcgcaaagc attcgaattc tttgtgataa
    16681 attcaatgag ggacaagaat ctatatttgt tcatttttat tgtccacaag aaatgcatct
    16741 aaaaaaagaa gagaaatttc atatttatcg aattatacaa gagttaataa ctaatgctct
    16801 aaaacactct cgagcaacag tagtttgtgt ttatctcatt caaagggact tttatataga
    16861 atgtattgta caagatgatg gcacaggctt tgattatagc aaaataaaac ttagaggatt
    16921 tgaaaataaa cattttggta ttctatcaat aaatcaagag gttaattcat taaatggaaa
    16981 aatgagagta tcatctgtaa atccacatgg tacaaaattt acaataactt taccgattgc
    17041 aaaggaggat atagattcat gaaagtatat ttattagacg atcatgcact tttctctaaa
    17101 agtcttgaaa ttgcatttca accaatggat gtctcaatta ctagttttac taatccagaa
    17161 ttttttttaa ataaactaaa aaatgagcaa ccagatttag cattattgga tatccatatt
    17221 ggagagttaa gtggatttga aatatctaaa gaaattattg gaaaatttcc aaatcaaaaa
    17281 atagtttttt tatcaggttt tgatttaatt gaatacaaga atgaagcaat aaaatctgga
    17341 gcatggggac tattaaataa aaatgtaaca attgaagaat tgtatgatga tttacaaaaa
    17401 atacatcatg gaactgatct gctacccaag tgccaaagta cattagatgt tcttagtaaa
    17461 cgagaaaaag agatactaaa atgtgctgca gaaggtttta agcagcagga gatagcagaa
    17521 caacttcata tcagtagaag aacagtaaat aatcatcttg tatccataaa taataagcta
    17581 gaggtaaatt caaccatttc tgcaattatt caagctattg aattgggaat tattagagta
    17641 aaaggatatt gatactaaaa aatgttgaaa ttatcaaaca tttattcaga aagatatgct
    17701 gtttacggaa taccataacc catgatataa gggctatttt ttcataactt agtttagcaa
    17761 ttttgtttcc tgaattctct tcaattgtgt aaacaacttc attttctact ttctcaacaa
    17821 tcccaacgta ataactgata gaatcaccat cccaatcaaa aaagatgata ttcccatttt
    17881 taggcaaact tcctttccta aaccattggt tattcgcttt aaaattttca ataccagttg
    17941 ggcaataggc aaaatgttcc attttaactc cagctttttc agcattataa gaaacaaaaa
    18001 tagcgcacca ttctacacgt ccattaaagc cataccattg ccaatatttc gttccaccct
    18061 tatgtattcc ttcattcaat tctttaagtg ctgcttttac aatagctgaa ttcccttgac
    18121 tattgttgtt ggaaatagaa gtgatgtatt gtttaacaat ttgagcataa aacatattgc
    18181 catacgcata acgataatca tagcctatgt tgatagctat aggattagtg taagtgactg
    18241 tttttccatc tgcttgagtt tttgagaatt gaatcgtaat aaagtggatg attgatcacc
    18301 tccataatcc gattaaaaaa ctcagattta gggtcaacgt acaagccttt tccattcatt
    18361 aaaacggaga ggaagaaaat gaactttgcc aagtaagatt ttccgtttac agtgggtcca
    18421 gtgatggcaa tgtgcgggct attggctttt ttatcggtga tatcatttag tataattgta
    18481 ctataaaaca attgaacaca ttgaaagggg aagaaatgta caaattcaaa aagtacaaat
    18541 ataaaggcga ggagcattat tttactggtg ttactctttt caaagtgaac gacaataaaa
    18601 ttatttcgct taaagaattt aaatcaataa caaatactta tcgtcctttc aagtagaata
    18661 atttagtgtt gcacttaaac tgtaacacta ggtttattat aaaaacgtac gttcttgttt
    18721 gtaaataact cttttgtcgt aattaattta ttcatgaaaa ctgactttgt tatagttatt
    18781 cgtttagctc gcatttttct tactaaaaac tatccaaaag tatccatatt tttatagttg
    18841 aaacggtttg aaactaaatc aaaactaact acaattgaaa aaaatcactg gtatttcaca
    18901 acattctaag aaaaagaata atgctgtcat accaacgatt agagcttatc agaagctctt
    18961 aaaaaaacta accctttgct ggaaggctct gtcagctagt ttttcactct accaacaaaa
    19021 taatcaacca aaataacaac ggaaagccaa acaagaaaca tactaatcat gcttcttcaa
    19081 agaaagtaca aataaaaaag cgatgactcg agaagaaaat ctctatggag tcatcgcttt
    19141 ttcttatatt ttagttaaaa aattatttta ctaaaggttg aagtaacttg ttccagaaac
    19201 taatgagtgg accagcacca aatgcacaaa taattgtacc aatcccaatt ggaccaccag
    19261 caataaagcc aattaatagg accaacaaat cttgtgcttt tcgaacagaa gcgtaaggtt
    19321 tgttgatttg ttgacagatg gttggcgcaa tcgcatcata gggggactcg ccctgatctg
    19381 tagccatgta taaggcgcag ccaaatgtaa aaatcaggac tccgacgaat aaagaaagta
    19441 gtttgccaat tgttgagcct cctaaactat cggcgtaagg ttgaagccaa gtagaaatct
    19501 gttgaatcaa aatccctact aaaagcatat ttaaaatagt tcctagacca atggcttttt
    19561 tgttttttaa atagacatag aataaaataa acgcattgac aataatttga aaaatgccta
    19621 attgcatacc aaacattgaa gaaagtccga tattcatagc agtgaaagga tcaactccta
    19681 aacctgccac tcttaaagtg gatgcgccaa tcccgataat aactaaacca attaaaatta
    19741 aaagaacatt tttgactagt ttcatggtaa gcctcctgaa tagattttgt gtgtgatagt
    19801 acaaagtctg caacaaaaat tcatagagaa ttttgttgca gactactttt taaccagctc
    19861 cgtgttggaa cgaagggtat agagacatcc cgccatctac aaagagtgtt gttccggtta
    19921 cgtatgagga ttcatcagaa gctaaccaag cggccgcagc agctacttga tttggtttac
    19981 caataatgcc cataggaacc atgctcgttg tttgttttaa ctgttcggga tcggaaaatt
    20041 tttcagcatt aataggtgtg ttaatcgctc caggcgcaat acagttggca cgaataccat
    20101 attccgcata ttccaaagcg attgttttcg tgaacatttc ggttgcgcct ttacttgccg
    20161 catagtgggc gaacgttggc caaggaattt tttggtgaac ggaggacata ttaatgattg
    20221 accctttgat tttttgatct ctaaatattc ggagtgcctc tctagaaccc aaaaagacac
    20281 cgtttaaatt gacatcaatg acacgttgcc attcttttaa tggcatatca attgtcggaa
    20341 aagaagcctc cacaccggcg ttatttaccc aaatgtcaac atgaccaaac tcttttaaag
    20401 cggtttcagc taacgcttta atatcttctt cattagagac atcagccttc acgaatttta
    20461 cgcgatctgc gtgcttggct tggacatctt caaattcttt aggcagctca ccgacatagt
    20521 cagcaacaac attcatgccc tctaagatat aacgcagagt aataaataat cctaaacccg
    20581 tagctgcacc agtgacaacg gccactttac catgtaattc tccatacatt gattcattcc
    20641 ccctaaaatt actattaata ctttcatggt agcacatgtc aatcagcgtg ttgataaaat
    20701 acgacaaact gtcggaaaag tttaggctct aaagttagct actattgttg aaggtcttta
    20761 aaaaaatact ggtcgtagta atcaattcct ctcatttata gagttttcta aaaaaacaca
    20821 aaatatctag gcgaagtggt caagtccaat ggttatttat gagtgaatat gctaaaataa
    20881 aacttgtctt acataaggaa agatttgttc actaacagtg gcgactgttc tcagtaaaca
    20941 gttgcactgg tttatcggga agggaacaga gcaagtttta cgagactttc ccatgtaata
    21001 ataaaaagca ctgaacgtca gtgaatgaag gaagaaggac atctatgaaa acaattatca
    21061 cattcattat tgtcttcggt attcttgtcc tcgtacatga atttggccac ttttattttg
    21121 caaaacgagc gggtatttta gttcgtgagt ttgcaatcgg aatgggacca aagatttttg
    21181 cgcatcgtgg aaaagatggc accacttata cgattcgctt attgccaatt ggtggctatg
    21241 tgcgaatggc tgggatgggt gaagacatga cagaaatcac accaggtatg cctctatctg
    21301 ttgagttaaa tgccgtgggt aatgtggtta aaattaatac aagtaaaaaa gtacaattac
    21361 ctcatagtat tccgatggaa gtcattgatt ttgatcttga aaaagaatta ttcatcaagg
    21421 gctatgtcaa tggaaacgag gaagaagaaa ccgtttataa agttgaccat gatgcaacga
    21481 ttattgaaag tgatggaacc gaggtgcgga ttgcgccact tgacgttcaa tttcaatcag
    21541 cgaaattatc gcaacgcatt ttgacgaact ttgcgggacc catgaataac tttatcttag
    21601 ggtttattct gtttacgtta gcggtctttc tacaaggagg cgtcactgat ttaaacacga
    21661 atcaaattgg acaagtgatt cctaatggcc cagccgcaga agctgggttg aaagaaaacg
    21721 ataaagtctt atcgattaat aatcaaaaaa tcaaaaaata cgaagatttt acaaccattg
    21781 tgcagaagaa ccccgaaaag ccgttaacgt tcgtagttga gcgtaacggc aaagaagagc
    21841 aactaacagt gacaccagaa aaacaaaaag tggaaaaaca aacgattggt aaagtcggcg
    21901 tttatcctta tatgaaaacc gatttaccgt caaaattgat gggcggtatt caggatactt
    21961 tgaatagtac gacacagatt tttaaagcac tcggctcact attcacaggc tttagtttaa
    22021 acaaactagg tgggccagtc atgatgttta aattatcgga agaagcatcc aatgctggag
    22081 taagtacagt tgtattctta atggccatgt tgtcaatgaa cttagggatt attaatttgt
    22141 tgccgatccc agctttagat ggcgggaaaa ttgtcttaaa cattattgaa ggtgtacgtg
    22201 gaaaaccaat tagtcctgaa aaagaaggca tcattacgtt aattggcttt gggtttgtca
    22261 tggtgttaat ggtgttagtt acttggaacg atattcaacg ctttttcttt taaggagaaa
    22321 gtttaagtaa aaaagtgtgt aaagaaatca aaaatagttg attttaaaat agaggagagt
    22381 tttaatgaaa cagtcaaaaa tgttaattcc aacgttaaga gaagtaccaa atgatgcaga
    22441 agtcttaagt catcaaattc tgttgcgcgc aggctatatt cgtcaagtcg ctgcagggat
    22501 ctattcttat ttacctttag ccaatcgtgt tttagaaaaa ttaaaaacga ttatgcgaga
    22561 agaatttgag aaaattgatg cagttgaaat gttaatgcct gcgttattac ccgcagaact
    22621 ttggaaagaa tcaggccgtt atgaaactta tggacctaac ttgtatcgct taaaagatcg
    22681 caatgaccgt gactatatct taggcccaac gcatgaagaa accttcacag aattaattcg
    22741 tgatgaaatt aattcttaca aacgattacc tttgaattta taccaaattc aaacaaaata
    22801 tcgtgatgaa aaacgcccac gttctggctt attaagaggc cgtgaattta tcatgaaaga
    22861 tggctattct ttccatgccg atgaagctag tttagatcaa tcataccgtg attacgaaaa
    22921 agcttactca cgcatttttg aacgctgtgg actagaattc cgtgccatta ttggggacgg
    22981 tggtgccatg ggtggtaaag attctaaaga atttatggcg atttctgaaa ttggggaaga
    23041 tactatttgt tattcaacag aaagtgatta tgctgccaat ttagaaatgg caacaagtct
    23101 ttatacgccg aaaaaatcac atgaaacaca attagattta gaaaaaattg caacaccaga
    23161 agtgggtaca attgccgaag tggcaaactt ctttgaagtt gagccacaac gaattattaa
    23221 atcagtacta tttattgccg atgaagagcc agtaatggtc ttggttcgtg gcgatcatga
    23281 tgtcaatgat gtcaaattga aaaacttctt aggcgctgat ttcttagatg aagcaacaga
    23341 agaagatgct cgccgtgtct taggagcggg ctttggttca attggtccag tcaatgtttc
    23401 cgaagatgtt aaaatttatg cagatttagc tgttcaagat ttagccaacg ccattgttgg
    23461 agctaacgaa gatggctatc atttgacaaa tgtaaatcca gatcgtgatt tccaaccaat
    23521 tagttacgaa gatttacgct ttgttcaaga aggcgatcct tctcctgatg gcaatggtgt
    23581 cttagccttt actaaaggaa tcgaaattgg tcatatcttt aaattaggaa cgcgttatag
    23641 tgatgctatg ggcgcaacag ttttagatga aaacggtcgt gaaaaatcag tgatcatggg
    23701 ttgctatggc atcggcgtta gtcgtttact ttcagcaatc gttgaacaaa atgcagacga
    23761 gcgtggtatt aattggccaa caggaattgc gccatttgat ttacacgtgg tccaaatgaa
    23821 tgtgaaagat gagtaccaaa caaaactatc acaagaagtt gaagcaatga tgaccgaagc
    23881 gggctacgaa gtattagttg atgaccgcaa cgagcgcgca ggcgtaaaat ttgctgatgc
    23941 tgatttaatt ggttgtccaa tccgtatcac agtcgggaaa aaagcagtcg atggtgtggt
    24001 agaagtcaaa atcaaacgta ctggtgaaat gttggaagta cgcaaagaag aattagaaag
    24061 tacactttct attttgatga acacaacatc agaagtggaa taataatgaa aagggcggac
    24121 agaatgatta ggataaactg tttccgccac ttatcagcgt ttaagcttga agcaaaaatc
    24181 taaagtgatt tttgcttcaa gctcttctta gctcttttta gaaaagaaac aagattgttt
    24241 ttttacaaaa aacgagtata cttaatagag aagcgaatgc agagaaaccg aaaaaaggca
    24301 cttgacagat ttgtctgagg gccttttttc aatgatagaa ggaggttcat tttgtgacag
    24361 aaaaagcacg cgatttattt ga
//
