LOCUS       NZ_CAAHQE010000001     41176 bp    DNA     linear   CON 19-DEC-2024
DEFINITION  Streptococcus pyogenes strain Bel002, whole genome shotgun sequence.
ACCESSION   NZ_CAAHQE010000001
VERSION     NZ_CAAHQE010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (03-APR-2019) WTSI, Pathogen Informatics, Wellcome Trust
            Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900985135.1-RS_2024_12_19
            Annotation Date                   :: 12/19/2024 10:09:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,745
            CDSs (total)                      :: 1,683
            Genes (coding)                    :: 1,623
            CDSs (with protein)               :: 1,623
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3, 1 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 28 of 60
            Pseudo Genes (incomplete)         :: 32 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 11 of 60
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:22:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 267091
            Orig. end                         :: 308267
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CAAHQE010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..41176
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41176
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41176
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21176](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21176
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            complement(702..1352)
                     /locus_tag="E9931_RS01300"
                     /old_locus_tag="SAMEA3919035_00265"
     CDS             complement(702..1352)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /locus_tag="E9931_RS01300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00265"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_002994021.1"
                     /transl_table=11
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFLTGLVFGLLLALLGRS
                     HQPLLHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYISE
                     VFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSSLAA
                     MITVPDIFQNAKIIGGREWDYMSMYILVAFIYWIIAFLLERYQEFLENKLALV"
     gene            complement(1381..2244)
                     /locus_tag="E9931_RS01305"
                     /old_locus_tag="SAMEA3919035_00266"
     CDS             complement(1381..2244)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /locus_tag="E9931_RS01305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00266"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_002994018.1"
                     /transl_table=11
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWETIKEKGVLKVATPG
                     TYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLNNF
                     DITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMKVAQ
                     KQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMSDVQY
                     NPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDKKIPII
                     DTKDVN"
     gene            complement(2362..3816)
                     /locus_tag="E9931_RS01310"
                     /old_locus_tag="SAMEA3919035_00267"
     CDS             complement(2362..3816)
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /locus_tag="E9931_RS01310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00267"
                     /product="amidase"
                     /protein_id="WP_011054384.1"
                     /transl_table=11
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSER
                     FEAALEEAKQRDFSGKPFAGVPIFLKDLGQELKGDLSTSGSKLFKNHHATKTDLFVKRL
                     EDLGFIILGRSNTPEFGFKNISDSQLHGPVSLPHDNTRNAGGSSGGAAALVSSGISALA
                     TASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTRNLLY
                     YLQMEQMESPFPLATLTKNSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALRQAVTWLR
                     EQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMETMTWAIY
                     QSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVPDSKLMAN
                     LAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEGLPMGIQLI
                     AAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            complement(4013..4642)
                     /gene="pyrE"
                     /locus_tag="E9931_RS01315"
                     /old_locus_tag="SAMEA3919035_00268"
     CDS             complement(4013..4642)
                     /EC_number="2.4.2.10"
                     /GO_function="GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /locus_tag="E9931_RS01315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00268"
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="WP_002984920.1"
                     /transl_table=11
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSY
                     PKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDHGA
                     GNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNF
                     KEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            complement(4700..5392)
                     /gene="pyrF"
                     /locus_tag="E9931_RS01320"
                     /old_locus_tag="SAMEA3919035_00269"
     CDS             complement(4700..5392)
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /locus_tag="E9931_RS01320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00269"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_136293708.1"
                     /transl_table=11
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGP
                     DIVRSIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGL
                     GQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAI
                     KAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDCIVVGRPITQAKDPVAAYQ
                     AIKAEWAG"
     gene            complement(5669..6205)
                     /locus_tag="E9931_RS01325"
                     /old_locus_tag="SAMEA3919035_00271"
     CDS             complement(5669..6205)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /locus_tag="E9931_RS01325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00271"
                     /product="hypothetical protein"
                     /protein_id="WP_021734032.1"
                     /transl_table=11
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEFP
                     AHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLIDL
                     CQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEEETF
                     IKYYQSPKVPTGEFE"
     gene            6427..7332
                     /locus_tag="E9931_RS01330"
                     /old_locus_tag="SAMEA3919035_00272"
     CDS             6427..7332
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /locus_tag="E9931_RS01330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00272"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_002984924.1"
                     /transl_table=11
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMGI
                     TIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFVVN
                     AFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDDNHL
                     TASPLFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMMSQMPH
                     NKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFIKHEKA
                     NLSKMGERFIEYLLEEVTFD"
     gene            complement(7412..8200)
                     /locus_tag="E9931_RS01335"
                     /old_locus_tag="SAMEA3919035_00273"
     CDS             complement(7412..8200)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /locus_tag="E9931_RS01335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00273"
                     /product="hypothetical protein"
                     /protein_id="WP_002994010.1"
                     /transl_table=11
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERRE
                     LNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRSVS
                     PILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSRNVT
                     TKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSSQAFL
                     ENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(8193..8906)
                     /gene="deoD"
                     /locus_tag="E9931_RS01340"
                     /old_locus_tag="SAMEA3919035_00274"
     CDS             complement(8193..8906)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="deoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /locus_tag="E9931_RS01340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00274"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_002990147.1"
                     /transl_table=11
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNM
                     FGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELV
                     LAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNM
                     PERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTF
                     TDMMKVGLETLIAND"
     misc_feature    9356..9369
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.2"
                     /tool="antismash"
     gene            complement(9569..10378)
                     /locus_tag="E9931_RS01345"
                     /old_locus_tag="SAMEA3919035_00275"
     CDS             complement(9569..10378)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /locus_tag="E9931_RS01345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00275"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_014635415.1"
                     /transl_table=11
                     /translation="MSLMTKINETKDFLVTKGIETPEFGLILGSGLGELAEEVENAIVI
                     DYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKALG
                     CEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLNEFGPRFPDMSDAYTKVYR
                     NKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVAAHSG
                     LKVLGISAITNFAAGFQSELNHEEVVEVTQHIKEDFKGLVKAILAEL"
     gene            complement(10362..10802)
                     /gene="arsC"
                     /locus_tag="E9931_RS01350"
                     /old_locus_tag="SAMEA3919035_00276"
     CDS             complement(10362..10802)
                     /EC_number="1.20.4.1"
                     /GO_function="GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /GO_process="GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /gene="arsC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /locus_tag="E9931_RS01350"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance.;
                     This arsenate reductase requires both glutathione and
                     glutaredoxin to convert arsenate to arsenite, after which
                     the efflux transporter formed by ArsA and ArsB can extrude
                     the arsenite from the cell, providing resistance; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00276"
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="WP_023613211.1"
                     /transl_table=11
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLI
                     ELLQSMGISARELLRTNVPEFEAYGLANQAVAEKDIINAMLADPILINRPIVVTRKGVK
                     LCRPSETLLDILPVPLPSPYMKEDGESVNPIEVKGEKDVIDD"
     gene            complement(10821..12032)
                     /locus_tag="E9931_RS01355"
                     /old_locus_tag="SAMEA3919035_00277"
     CDS             complement(10821..12032)
                     /EC_number="5.4.2.7"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008973 - phosphopentomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /locus_tag="E9931_RS01355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00277"
                     /product="phosphopentomutase"
                     /protein_id="WP_032462954.1"
                     /transl_table=11
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISEA
                     AGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGLNI
                     TEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTS
                     ADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRH
                     DYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGIINDMGHNKSNSHGIDTLIKTLQ
                     LPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLLLITADH
                     GNDPTYAGTDHTREYIPLLAYSVSFTGNGLIPQGHFADISATVAENFGVDTAMIGESFL
                     SHLK"
     gene            complement(12109..12792)
                     /gene="rpiA"
                     /locus_tag="E9931_RS01360"
                     /old_locus_tag="SAMEA3919035_00278"
     CDS             complement(12109..12792)
                     /EC_number="5.3.1.6"
                     /GO_function="GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /gene="rpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /locus_tag="E9931_RS01360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00278"
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="WP_021733827.1"
                     /transl_table=11
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEG
                     LQVVGVTTSSVTSKQAEVLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLME
                     KIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDS
                     RLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLE
                     APTAG"
     misc_feature    complement(13026..13039)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.77"
                     /tool="antismash"
     gene            13170..15269
                     /locus_tag="E9931_RS01365"
                     /old_locus_tag="SAMEA3919035_00279"
     CDS             13170..15269
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /locus_tag="E9931_RS01365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00279"
                     /product="AAA family ATPase"
                     /protein_id="WP_010922175.1"
                     /transl_table=11
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEE
                     FQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEIQD
                     TAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSLEAG
                     TQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSR
                     GELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHIT
                     LPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEIAKQKES
                     QEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMG
                     TNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGKRPIGSFLFVGPTGVGK
                     TELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRN
                     PYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFGQQDTE
                     TSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKESLEEIVDLMLAEVNQTTAKKGISLT
                     ITDDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVI
                     RQNDQ"
     gene            complement(15327..16070)
                     /locus_tag="E9931_RS01370"
                     /old_locus_tag="SAMEA3919035_00280"
     CDS             complement(15327..16070)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /locus_tag="E9931_RS01370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00280"
                     /product="hypothetical protein"
                     /protein_id="WP_002984942.1"
                     /transl_table=11
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSSI
                     EGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQVER
                     DIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFEKLA
                     SQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFDYTRF
                     GKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(16218..16817)
                     /gene="yihA"
                     /locus_tag="E9931_RS01375"
                     /old_locus_tag="SAMEA3919035_00281"
     CDS             complement(16218..16817)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yihA"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /locus_tag="E9931_RS01375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00281"
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="WP_011184414.1"
                     /transl_table=11
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSF
                     INTILGRKNLARTSSKPGKTQLLNFFNIDNKLRFVDVPGYGYAKVSKSERAKWGKMIEE
                     YLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHES
                     VVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            complement(16827..18056)
                     /gene="clpX"
                     /locus_tag="E9931_RS01380"
                     /old_locus_tag="SAMEA3919035_00282"
     CDS             complement(16827..18056)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /locus_tag="E9931_RS01380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00282"
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="WP_002984948.1"
                     /transl_table=11
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEI
                     IKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDD
                     DDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLK
                     LIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVP
                     PQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASY
                     MQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDG
                     VELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVE
                     GKSKPVLETA"
     gene            complement(18186..18356)
                     /locus_tag="E9931_RS01385"
                     /old_locus_tag="SAMEA3919035_00283"
     CDS             complement(18186..18356)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /locus_tag="E9931_RS01385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00283"
                     /product="hypothetical protein"
                     /protein_id="WP_002984950.1"
                     /transl_table=11
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLASLFLLNAFTNLV
                     NSIHAFYGTLF"
     gene            complement(18376..18873)
                     /locus_tag="E9931_RS01390"
                     /old_locus_tag="SAMEA3919035_00284"
     CDS             complement(18376..18873)
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005542 - folic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /locus_tag="E9931_RS01390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00284"
                     /product="dihydrofolate reductase"
                     /protein_id="WP_002984955.1"
                     /transl_table=11
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAILM
                     GRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGGNK
                     VLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVTALK
                     HK"
     gene            complement(18953..19792)
                     /locus_tag="E9931_RS01395"
                     /old_locus_tag="SAMEA3919035_00285"
     CDS             complement(18953..19792)
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /locus_tag="E9931_RS01395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00285"
                     /product="thymidylate synthase"
                     /protein_id="WP_011017679.1"
                     /transl_table=11
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFA
                     EYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRT
                     IGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVR
                     RVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYD
                     NQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI"
     misc_feature    complement(19748..19762)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.77"
                     /tool="antismash"
     gene            20001..21176
                     /locus_tag="E9931_RS01400"
                     /old_locus_tag="SAMEA3919035_00286"
     CDS             20001..21176
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /locus_tag="E9931_RS01400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00286"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_063812327.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 2.1e-07,
                     bitscore: 25.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSVA
                     PITEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFARS
                     FEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAILVT
                     ADPRILALNEDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQKRENL
                     QLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGNIYTGS
                     LYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQALLDQRT
                     RLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHRRIYHTNDKN"
     gene            21163..22440
                     /locus_tag="E9931_RS01405"
                     /old_locus_tag="SAMEA3919035_00287"
     CDS             21163..22440
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /locus_tag="E9931_RS01405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00287"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_002984963.1"
                     /transl_table=11
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLPI
                     QTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSGGF
                     KAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTIHLE
                     EKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESLVTTS
                     CEIPVRLLDRDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIATGNDWR
                     AIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPTVSIAHD
                     LLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGATQDEIAP
                     LVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(22670..23659)
                     /gene="fni"
                     /locus_tag="E9931_RS01410"
                     /old_locus_tag="SAMEA3919035_00288"
     CDS             complement(22670..23659)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /locus_tag="E9931_RS01410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00288"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_010922169.1"
                     /transl_table=11
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLSTH
                     FAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRL
                     HEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTWKKH
                     LAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRGGDRS
                     YLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVE
                     KYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(23652..24659)
                     /locus_tag="E9931_RS01415"
                     /old_locus_tag="SAMEA3919035_00289"
     CDS             complement(23652..24659)
                     /EC_number="2.7.4.2"
                     /GO_function="GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054377.1"
                     /locus_tag="E9931_RS01415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00289"
                     /product="phosphomevalonate kinase"
                     /protein_id="WP_136293709.1"
                     /transl_table=11
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAH
                     IQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIVTGKMERDGKKF
                     GIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVA
                     YTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQV
                     TASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVA
                     ACQKQDAVVKSSGSGGGDCGIALAFNQDARDTLISKWQEADIALLYQERWGEND"
     gene            complement(24652..25596)
                     /gene="mvaD"
                     /locus_tag="E9931_RS01420"
                     /old_locus_tag="SAMEA3919035_00290"
     CDS             complement(24652..25596)
                     /EC_number="4.1.1.33"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /locus_tag="E9931_RS01420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00290"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_002984972.1"
                     /transl_table=11
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFTT
                     TSISFLPDTATSDQFYINGVLQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAAGL
                     SSSSSGLSALVKACDQLFNTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAIYKV
                     ETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLKTNNF
                     EKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMDAGPNV
                     KVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            complement(25578..26456)
                     /gene="mvk"
                     /locus_tag="E9931_RS01425"
                     /old_locus_tag="SAMEA3919035_00291"
     CDS             complement(25578..26456)
                     /EC_number="2.7.1.36"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /locus_tag="E9931_RS01425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00291"
                     /product="mevalonate kinase"
                     /protein_id="WP_136293710.1"
                     /transl_table=11
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFPA
                     DKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRSVF
                     SYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIALNGY
                     LIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQLMTQA
                     HSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKISHRLKE
                     EGAVNTWIQML"
     gene            complement(26750..27982)
                     /locus_tag="E9931_RS01430"
                     /old_locus_tag="SAMEA3919035_00292"
     CDS             complement(26750..27982)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /locus_tag="E9931_RS01430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00292"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_002993949.1"
                     /transl_table=11
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRILH
                     LISSNKGKLPDTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDREE
                     AQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLAVSM
                     MLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNELVEL
                     MTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAEDFKSLV
                     LKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIGRRRKRA
                     KLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFKGTITVNY
                     KNDAIVFTVVI"
     gene            complement(27991..28659)
                     /locus_tag="E9931_RS01435"
                     /old_locus_tag="SAMEA3919035_00293"
     CDS             complement(27991..28659)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /locus_tag="E9931_RS01435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00293"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002984985.1"
                     /transl_table=11
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAY
                     DIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFS
                     LKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLN
                     QGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
                     "
     gene            complement(28662..29312)
                     /locus_tag="E9931_RS01440"
                     /old_locus_tag="SAMEA3919035_00294"
     CDS             complement(28662..29312)
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /locus_tag="E9931_RS01440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00294"
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="WP_011054374.1"
                     /transl_table=11
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGF
                     KLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVDLL
                     KSIPGMSVNAEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTIAQD
                     SWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     misc_feature    29527..29540
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     misc_feature    complement(29528..29541)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            29532..31544
                     /locus_tag="E9931_RS01445"
                     /old_locus_tag="SAMEA3919035_00295"
     CDS             29532..31544
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /locus_tag="E9931_RS01445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00295"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="WP_136293711.1"
                     /transl_table=11
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGALD
                     NTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVRASPANSAL
                     LQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEAS
                     HQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQNYEH
                     YQFLDVAETIAKYAKELQEQHVHAIVVLAHVPATSKDGVVDHEMATVMEKVNQIYPEHS
                     IDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSANVVAVAP
                     GIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNLVTTAQLT
                     IAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQMTGQHIYDV
                     LNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLTTTYTVVVND
                     FLYGGGDGFSAFKKAKLIGAINTDTEAFITYITNLEASGKTVNATIKGVKNYVTSNLES
                     STKVNSAGKHSIISKVFRNRDGNIVSSEIISDLLTSTENTNNSLGKKETTTNKNTISSS
                     TLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     misc_feature    complement(29543..29556)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.33"
                     /tool="antismash"
     gene            complement(31625..32035)
                     /locus_tag="E9931_RS01450"
                     /old_locus_tag="SAMEA3919035_00296"
     CDS             complement(31625..32035)
                     /EC_number="3.5.1.88"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /locus_tag="E9931_RS01450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00296"
                     /product="peptide deformylase"
                     /protein_id="WP_002984994.1"
                     /transl_table=11
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMA
                     ANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITVEY
                     LDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(32291..32509)
                     /locus_tag="E9931_RS09075"
     CDS             complement(32291..32509)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995561.1"
                     /locus_tag="E9931_RS09075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002984997.1"
                     /transl_table=11
                     /translation="MALLFYYYVRKNQVKKLSQLKNLTEIFRKFIILTINNISVIKAFQ
                     TAGVLFGPVKAANARESSIWFENLTKQ"
     gene            <32740..>32817
                     /locus_tag="E9931_RS08940"
                     /pseudo=""
     CDS             32740..>32817
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /locus_tag="E9931_RS08940"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDYCNNKRIKIKRKGLSPLQHRTKSF"
     gene            complement(32915..34792)
                     /locus_tag="E9931_RS01465"
                     /old_locus_tag="SAMEA3919035_00297"
     CDS             complement(32915..34792)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /locus_tag="E9931_RS01465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00297"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_136293712.1"
                     /transl_table=11
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTTL
                     LDVLSERLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSSDVKAIQLIRQYE
                     LLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGMRRR
                     VQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHVANRI
                     FELDKAGLTEYQGNYQDYVRLKAEQDERDAANLHKKKQLYKQELAWMRTQPQARATKQQ
                     ARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQ
                     NKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMDETKRVIN
                     YLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLKLLIEKPNV
                     LLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFEEGDIRVFYG
                     NYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKKRMSYLEKQEWAQIEDKIATIE
                     ANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLDI"
     gene            complement(34789..35997)
                     /locus_tag="E9931_RS01470"
                     /old_locus_tag="SAMEA3919035_00298"
     CDS             complement(34789..35997)
                     /EC_number="2.7.7.72"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /locus_tag="E9931_RS01470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00298"
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="WP_032464310.1"
                     /transl_table=11
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIHD
                     VDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQVS
                     FVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLKQKRLRAVGKAEERFEEDALRI
                     MRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGISAMIA
                     CQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTS
                     NDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDHIEALDQ
                     ALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREE
                     LAT"
     gene            complement(36122..36970)
                     /locus_tag="E9931_RS01475"
                     /old_locus_tag="SAMEA3919035_00299"
     CDS             complement(36122..36970)
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /locus_tag="E9931_RS01475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00299"
                     /product="DegV family protein"
                     /protein_id="WP_002990194.1"
                     /transl_table=11
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLSI
                     DDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLA
                     EEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIMVDD
                     LNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLI
                     ADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPR
                     L"
     gene            complement(36970..37350)
                     /locus_tag="E9931_RS01480"
                     /old_locus_tag="SAMEA3919035_00300"
     CDS             complement(36970..37350)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /locus_tag="E9931_RS01480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00300"
                     /product="DUF1149 family protein"
                     /protein_id="WP_002985011.1"
                     /transl_table=11
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDEQ
                     QKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDMVK
                     RLTYEVTEIALDRPGIHLEFKN"
     gene            complement(37578..37754)
                     /locus_tag="E9931_RS01485"
                     /old_locus_tag="SAMEA3919035_00301"
     CDS             complement(37578..37754)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E9931_RS01485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMEA3919035_00301"
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="WP_002985013.1"
                     /transl_table=11
                     /translation="MIKLYGFKYGLVGEVLRRIERLGFTFERLELRQASSKYLAKHDEA
                     LVINLFILDLKLT"
     misc_feature    complement(38178..38191)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.36"
                     /tool="antismash"
     misc_feature    38222..38235
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.62"
                     /tool="antismash"
     gene            38258..39277
                     /gene="ideS"
                     /locus_tag="E9931_RS01490"
                     /old_locus_tag="SAMEA3919035_00302"
     CDS             38258..39277
                     /codon_start=1
                     /gene="ideS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /locus_tag="E9931_RS01490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00302"
                     /product="immunoglobulin G-degrading enzyme IdeS"
                     /protein_id="WP_011054369.1"
                     /transl_table=11
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIRYSEVTP
                     YHVTSVWTKGVTPPAKFTQGEDVFRAPYVANQGWYDITKTFNGKDDLLCGAATAGNMLH
                     WWFDQNKDQIKRYLEEHPEKQKINFNGEQMFDVKEAIDTKNHQLDSKLFEYFKEKAFPY
                     LSAKHLGVFPDHVIDMFINGYRLSLTNHGPTPVKEGSKDPRGGIFDAVFTRGDQSKLLT
                     SRHDFKEKNLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSNGNLKAIY
                     VTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQDSWNQTN"
     misc_feature    complement(39304..39317)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.28"
                     /tool="antismash"
     gene            39379..40143
                     /locus_tag="E9931_RS01495"
                     /old_locus_tag="SAMEA3919035_00303"
     CDS             39379..40143
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679956.1"
                     /locus_tag="E9931_RS01495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00303"
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="WP_269459910.1"
                     /transl_table=11
                     /translation="MTLFILMCSSIILYTTKGIFSDTYITNDIRNSEDIYFPRQDKDGI
                     LDNKRLKDIYGKEIIEKTNIPINAKQGTHLIFNTNENTTVWDDNTFTKVISSNLSPSQE
                     RMFNVGDHVNIFAIVKSYQVVCKDQFNYIDGGIIKTSDVKPEEKAIYINIISDKELRAL
                     TAKDKLTFKNNMVTLQEIDVRLRKSLMGDSKIKLYEYGSLYIKGFWDIHYKDGTTRHTN
                     LFSYPDYTDNEIIDVGKVSHFDVYLNKDILYE"
     gene            40266..40982
                     /locus_tag="E9931_RS01500"
                     /old_locus_tag="SAMEA3919035_00304"
     CDS             40266..40982
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013303.5"
                     /locus_tag="E9931_RS01500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919035_00304"
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="WP_023611001.1"
                     /transl_table=11
                     /translation="MKRLIIKSILVFFLMFIYTFKTEKLVESKNSNIDEIKHQLRYIYT
                     ITPSDYSNCNISYLTTHNFSVATPGYQSKCFYVDSEVDGGVTEKFRKGQKVNVFGLPYI
                     FSPYNKNDIYGGITPSTDDGILRTNTIAGNFFIDGQQQKTLINPIKIDKDIVTIQEFDF
                     KIRKFLMESKEIYLTKSPYIRGSLEIHSKNRKHEKINLYDAKPNSTRSDVFKKYKDNKT
                     INMKDFSHFDIYLWTK"
     misc_feature    complement(40307..40325)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.6"
                     /tool="antismash"
ORIGIN
        1 cgataagatg acaaagggct tggatgaggg ctctcgatga tgtggtgctt tggattagta
       61 atgaaggctt ttttcttcct tgcataggct ccccacaaaa tgaaaactac agggctgtct
      121 ttctcattca gcactttaat aacagcgtct gtaaatggct cccatattaa gcctgcatgc
      181 ccattagcct ggcctgctgg cactgttaag caagcattca aaagcagaac cccttgacta
      241 gcccaagtgc ttaaatcatg atggtcacga ggaccaatgt catctgctaa ttcttttaaa
      301 atattaataa gggatggcgg agcagaaatc tcttctggaa ctgaaaatga taagccctgg
      361 gcctgtttgg ggccatgata agggtcttgt cctaaaatca acactttggt ttcttccaaa
      421 ggagtgactt gtaaggcttt aaagacattt tctcgttggg ggtagacaag accggaagca
      481 taggcttcat ctaaaaagtg attgatgcga ccgtagtaat gctccggcaa aaatgatttg
      541 attttctcat gccaaattga atgagccata agattccttt ctaatcacgt cagtttctaa
      601 gttaaatacg atgtcctttt ctatctagtt taccacattt taaatagaaa gaccctgaaa
      661 atatgatatt tccagggtta atattcgttt tttacaggat attaaacaag tgctagctta
      721 ttttctaaga attcttggta acgttctaac aaaaaagcaa taatccaata gataaaggct
      781 actaaaatgt acatggacat gtagtcccac tccctaccac cgataatttt ggcattttga
      841 aaaatatctg gtacggtaat catggcagct agcgacgaac ttttaaccat atcaataatg
      901 acattgccta gaggaggaac tgcaattcta aaggcttgag gaagaataat tttcttaacc
      961 ataagagcat atggcaaccc taaagcctta gctgcttccc actgtccctt gtcaatagct
     1021 tctatagaag agcgaaaaac ttcagaaata taggcagcgc taaccataga aaaaccaaga
     1081 taagcgcaaa gtaaagctgg caattctaaa ccataataag gcaacccgaa ataaagaaca
     1141 aagagcacca cgatcatcgg cacacctcgc ataatagaga tgtaggccct aacaagatag
     1201 tgtagcagtg gctgatgtga ccttcctagt agggcaagga gcaaaccaaa gaccagcccc
     1261 gttaaaaagc taagcaacga tatgccaagg gtataaggta atcccgataa tacaaatcct
     1321 aaactatctt tcattaatgg gatattaatc atgtggttag gactccttta acatcaagta
     1381 ttagttaacg tctttcgtat caatgatggg aatttttttg tctttgccaa aaggttttgt
     1441 caaatcttga ccagcatagt aggtttcaga tattttcttc aagctaccat cttttatcat
     1501 gtctttaata acagcatcta tttttttctt gaggctatcg tcttttttgt tcataacaat
     1561 tccttgttcg gttgggttgt actgaacatc gctcattttg acatttagat ttggattttg
     1621 agataacatg taatccacaa ataatttttg agctgggtaa tcatttggaa tgaaatctgt
     1681 tcgaccgtta gccacatcgt ttagataaac atctcctgta acattatcgt aggtcaccag
     1741 ttcagctccc tgtttttgcg ctactttcat gtactctgtt ccagaagcgc cagctgcttt
     1801 ttttcctttc cagtcgctaa gatctttttt agccatgttt gagctgccat cagcacggac
     1861 aatcatgcct cctaccccgt atttataagg cgtagagata ttgtattttt tctgacgttt
     1921 tggggtaatg tcaaagttgt tcaaagaaat atccactcga ccactatcaa ctgaggtaaa
     1981 ggcttggtca aatcctgttt caacaaactt gactttaatg ttaagtcgtt taccgatttc
     2041 cttgaccata tctacttcgt aacctactaa ctcattatta tcgttgtaaa aagaagttgg
     2101 ctgataggtt cctggggtag ctacttttaa cacccctttt tctttgatag tctcccaact
     2161 tgatttttga gatttatgtg gcgcacatgc tgccaataaa aggctggcaa gtccgataga
     2221 cagtaaagta actgatttct tcatagtaac tcctttatta agataagaat agtataacat
     2281 tttgattaag ttgtgttatc agtgagcgct caatctcttt aaaaagttaa tctataatag
     2341 ttaaactgtt ttataagatt attattgagg aatcttcaat aatcctgctg cctcaaactg
     2401 ctctgcaatt cctaataata ggtcctctct acctttggct gcaattagtt gaatgcccat
     2461 tgggagccct tccttagttt cgtaagtagg taaactaata gctggctggc cagttagatt
     2521 aggcagagct gtgtaaggat taatagccag actcttacca aacatggttt cgaccaaatt
     2581 gaattgctct tcactgctga aaatttcagc ttgagccaag ttagccatga gtttcgaatc
     2641 tgggacaagt tctccgtgct taggagctgg tgtgttggtt gtgaacgtca acaacaggtc
     2701 ataagtctca tgaaaactag ccatggttgc actgtacgta tcccattttt gaaggacctg
     2761 tgagtaacgc caagctggga tgtctttacc tgattggtaa atagcccagg tcatggtttc
     2821 catatcgtct ttggtcatcg gacgtccaaa agtgtcttca atatcagcaa acatagcagc
     2881 cgtttccaca ctattcataa tataataatg acgaatcact tctgtcatat ttacaggaaa
     2941 ctcttccaat tcaactagct gatgcccttg ttctcttaac caagttactg cttgtcttaa
     3001 agcttttgca gtatctaaag atactgggct accgtcactt aaccgttgat aaaaagcaat
     3061 tgtcaaggga cgttgtagcg attgataaat actatttttt gttaaggtgg ctagggggaa
     3121 ggggctttcc atttgttcca tctgtaaata gtagagtaga tttctagtat ctctaacgga
     3181 tttggtcaag gcaaaatgaa ctgaggctcc ttgccagctt cgataagaac caggtccgac
     3241 aggcatgcgc ccgcggctag gtttgagccc aattaagcca ttaaacgagg ctggaattcg
     3301 aatagaacca ccaccatcac tagcagttgc tagtgcacta attcctgatg acactagagc
     3361 agcagctccc ccagatgagc caccagcatt tcgtgtatta tcatgaggta atgaaaccgg
     3421 gccatggagc tgactatcac taatattttt aaagccaaat tcaggtgtgt tagaacgccc
     3481 taaaataata aatcccaagt cttctaacct tttcacgaat aaatctgttt tagtcgcatg
     3541 atgattcttg aatagcttag aacccgatgt tgataagtct cccttcaatt cttgtcccaa
     3601 atctttcaaa aaaatgggaa ctcctgcaaa aggcttacct gaaaaatccc tttgtttggc
     3661 ttcttctagg gctgcttcaa agcgttctga ggtaatagca tttaaggtag ggttcaactt
     3721 tttagcctta taaatagcct gggttactaa ttctagtggt gtggtctgac cggtctgaac
     3781 agcaatagcc atagccgtcg catcttgata agtcatagct actcttcctt tctaagatat
     3841 gaatcctaaa acattctttt ttattaaaac acaaataaaa gaaaaccacc attaaaaggt
     3901 tagaaattag aatgtgatgt gtaaggaatg tagacaaaac aatcaaaaca taacattttg
     3961 aattggggtt aaagagattt tttcattaaa aataaacctg gctgatagtt ccttattgtt
     4021 gccagtttac ctggtcttct ttaaattttt taagtaaatg taaaccatca ttagtaatat
     4081 agccttgcaa ctttgcaact gcaattagct cagtataatt agaaagcgta atcaacttga
     4141 taccagcttc tttaaaattc tgactagctt ttggtaactc ataagtgaaa atcgcaacaa
     4201 ctcctagaac gtcagctccc tcacgactgg ctgctgcggc tgcatctagt accgaaccac
     4261 ctgttgaaat caaatcttca atgataacca ttttttggcc tttaagcaca cgcccctcaa
     4321 tctggttgcc tgctccatga tcttttggct tactgcgaat ataagcaaaa ggaagagtca
     4381 ttttatctgc tataatggca ccgtgaggaa tacctgctgt agctgtacca gcgatgacct
     4441 caacttctgg gaaatgagcc ctgatagttt ccacaaaccc attctcaatt aaatcacgag
     4501 tcttaggata agaaagggtg acacgattat cagtgtaaat aggtgattta atgccagatg
     4561 cccacgtaaa aggatcttca ggctttaaat aaacagcttt aatatcaagt aattgagttg
     4621 caatttggct tgctagtgtc atttcttatt ctcctttttc ttctttaaca gacaagtgtt
     4681 ggtttcctaa tcttatctgt tagcctgccc actcagcttt tatggcttgg taagcagcca
     4741 ctgggtcttt tgcctgggta attggtcgcc ctaccacaat acaatcactt ccaatgcgtc
     4801 ttgcttggtt tggagtcatc actcgttttt gatcgccaat attactgcct ttaggacgaa
     4861 tgccaggagt taagcaagta aatcccgtag gcgtcaccgc cttgatagct tctacttctt
     4921 gtgccgaaca aaccacccca tctagctgag ctttagctgc ccccttgctg taatgcaaaa
     4981 cagactctaa aagactcgtt tgaatatttt gatcaccacg catttggtct tcactggttg
     5041 aagttagctg cgttaccgca attaaggtag ggccttggcc tagtccttct cgagctgctt
     5101 ttagcatctc tacaccacca gctgcatgaa cagttgccat atcaatatct aattctttaa
     5161 gaactgccat agcagcacga acagtatttg gaatatcatg taattttaaa tccaaaaata
     5221 cattatgccc taacgatttg atagaccgaa caatatctgg tccttgcgca taatataatt
     5281 ccataccaat tttcacgtat agcttttctt ctgctggaaa taagtctaaa aatgctttag
     5341 tctcctcaaa tgatgaaaag tctaaagcaa taattgggcg ttcttctttc ataacttatc
     5401 ctttctataa tgtgtcaata tctcattaag caccaaaaag cctcgctacc aaagaagcga
     5461 ggctacagca aactaaaagg gaattccctt tttttatctt gtataccttg tttgcctctc
     5521 tggactcact taaaggtgtc taaatttaaa ctattatagc ttttttaaaa caagatgtca
     5581 aaactttttg ttatttgaac acatttttcc tactatatct ttttttgtat acttacgtca
     5641 actcatttta tcatttttac ccaatcattt attcaaactc acctgtgggt accttagggc
     5701 tttggtaata ttttataaaa gtttcttctt caagattaac cctctggata tgttcataga
     5761 gcacatccgg aataggagct tccttaagtg acaaagcact cacttttaaa gatgaaaaaa
     5821 catcacttaa gaccccaaaa actcgaatgc gtttatctcc aataataatt tgaaagactt
     5881 ctttggactg gcataaatct atcagatgat ccactccttt aatccaatta tcgacaatat
     5941 ccaaagtttt gttcatcaac ttaaaagctg attcttcata ccaaaaggta gactcaatca
     6001 agcgttgctg catatccaag gtatcaatgg ccgcaacaat atctcccaac tcagactgta
     6061 ctaaatgagc tggaaattcc cctccaagta tagaaggagt tcgttctaca agcttcagtt
     6121 catctcgaaa aagagtcaaa tagtggatac tgaccaataa cttttggatt aagatttgat
     6181 gactattttg ttcagtaaca ttcacacgac caccaccctt tgattagaaa aatacctatt
     6241 tgttaatact attaatataa cacaagaaaa ataaaagggc aatgaaattg atagattcaa
     6301 ctctcaaaat tgaatcatat ttatcctagg ccatatcgag aaaagactcc agcgcttttt
     6361 caaagttcta aacccatgat gacgtttgtg cttgcgtctt tatttttttt gagctagact
     6421 gtacttatga gaattcaaca actgcattat attatcaaaa ttgttgagtg cggctctatg
     6481 aatgaagctg ctaagcaatt atttatcaca caaccaagtc tatccaatgc ggtcaaggat
     6541 ttggaaatgg agatgggcat taccattttc aaccgaaatc ctaaagggat caccttgaca
     6601 aaagatgggg tggaattttt atcttatgct cgccaaatta tagagcaaac atcactgtta
     6661 gaagaccgct ataaaaacca caatactggc cgagagctct ttagcgtttc atctcaacat
     6721 tatgccttcg tagtcaatgc atttgtctca ctcctcaagc ggaccgacat gactcggtac
     6781 gaactctttt tgcgcgagac aagaacttgg gaaatcattg atgatgtcaa aaactttcga
     6841 tctgaaattg gtgttctctt tatcaacgac tataaccgag atgtcttgac caaattattt
     6901 gatgacaatc atttgactgc ctctccatta tttaaggcac agcctcatat ttttgtcagc
     6961 aaatcaaatc ctctagcaac taaaagccta ttaagcatgg acgacttgag agattttcct
     7021 tacctgagct atgaccaagg gattcacaac tccttttatt tttcagaaga gatgatgtcc
     7081 cagatgcccc acaacaaatc aattgtggtc agtgaccgtg ccaccctctt taacttaatg
     7141 attggtttag atggctacac cgttgccagt ggtattctaa atagcaatct aaatggtgac
     7201 cagattgtgg ctatcccgct agatgtccct gacgaaattg acattgtttt tatcaagcat
     7261 gaaaaagcca acttgtccaa aatgggggaa cgttttatcg aataccttct cgaagaagta
     7321 acctttgatt aatgtctttt tcaatcgtca tactaaaaaa acacggtagt aagacctgta
     7381 tcggtcaagt tatcgtgttt tttgataaat atcagacaat agattgtctc caaaggctca
     7441 actccttttt aataatggca ttcatgtcat caaagtaaaa aggctcacgt cggtagatta
     7501 caccagaaaa agtcgccaag gtgataatgt tttccaaaaa agcctgagaa gaaaaatgag
     7561 tggtgcgatg cagttcctct tcatcaaaag gcttaatcaa atgagccaga ggattacgga
     7621 cagccttttc aaaatgtcgt aacaaaaaaa ccaagtcctt gatttcttga ggtaaggagg
     7681 tcaacgtcaa catgtctgct aagcttttgg tcgtcacatt gcgagactgc ttttgagaca
     7741 ggtaagcctt aaaaacctcg tgatcagatt ccaacatggc ctgaaaatgc caggtatcat
     7801 attggtcatt ctttgtatca aaaatataag ccttgaagtt tggaatttct gacgtgatta
     7861 gtctgagaaa aagtcggtaa agaataggcg acactgacct gacgaaatca ataatagcac
     7921 cgttttttac tttaacttct aaatccaaaa tgtaattggc aatctgctca tcttcaagcg
     7981 attggttaag ccataatgaa cagtggtact ggtcttcaat ggtccgattc tctgctgcat
     8041 gttccgccag aaaggcaagg ttcaattctc tgcgctcttt taacatctct agtaaataga
     8101 gggcagtttt agggatattt ggcaaggctt tagcaattct aaaggcgtga ttataagcat
     8161 agacatccaa aaggatgtct agtgtttgat tattagtcat tggcaattaa ggtttccaag
     8221 ccgaccttca tcatatcagt gaaagttgtt tggcgctctt cagctgtagt atcttcggtt
     8281 ggatcattca agttatctga gatcgtcatg attccaaggg ctttgacatg gtgctgagca
     8341 gctaaatagt aaagagctgc tgcttccatt tcgatggctt taacacccaa tttaccaaga
     8401 gccatattac gctcaggcat gttagtgtaa aagacatcag aagaaagcac attcccaacg
     8461 tgagttgtta ctcccatttc tctggcgata tggtaagcct tgtcaagtaa accaaaatca
     8521 gcaatttgtg ggaaatcaaa ttctgggaag tcattacgga taatatttga gttggttgct
     8581 gctgcttggg caagcaccaa ttcacgcaca tgaacttctg ggtcaatcgc acccgcagta
     8641 ccaacacgga tcaatgtttt gacaccgtaa tcaacgatta attcacgagc atagatagag
     8701 atcgaaggca tccccatacc agttcccatg acagaaacgc ggtgcccttt gtaagttcct
     8761 gtgtagccaa acatgttacg cacttcgtta aaacacactg catcttctag gaaattttca
     8821 gcgataaatt tcgcgcgcaa aggatctcca ggtagaagaa ttttatcagc aatatcgcct
     8881 tttttggcag aaatatggat agacataaat tatgatactg agggcgttaa aagaacgatg
     8941 gcaaaatagg aagttagcag aaaatcctga ttttctagac aacttatctt tttgaccaag
     9001 tccttagccc gaattcaaat taatgaactc agccctcacc tttcttattt ttttattttt
     9061 tataaggaag aaaaacagtt ctccgcccgt attcaattca atgaatacag ttagccctac
     9121 ctttcctttt attttgtaga aggtcagagg gcggacagaa agcgactgaa atttagggaa
     9181 ctaacgccat gtgtgagctc aaaagttagt ttatctagtt tccgagcttt ccgcccgtat
     9241 tcaattgaat acaaccccat tcctttcata attgatattg aatagaagag agctaaaaat
     9301 cgagttcaaa taagaaagga ctaactctct ttcctttatt atttaaaaat taatacgaag
     9361 aaatgttcga gtccatactc aatttaaacc gaatacgtct ctttcccttc gttggttatg
     9421 ttagttagaa aagctagaat ctgagttcaa cattcatgga actcacactc cgtgattatt
     9481 ttttgatttt tttattgcga acagatgtgc caaactgacg acataaaata acattcctgt
     9541 aataatgctc cagttgattt tgttcgtcct acaactccgc taaaatagct ttaacaagac
     9601 ctttgaaatc ttctttgata tgttgggtca cttccacaac ttcttcatgg ttcaattctg
     9661 attgaaaacc agctgcaaag tttgtaatag ctgaaatacc aagtacttta agtccagaat
     9721 gagcagccac aataacttct ggtacagttg acatgccaac agcatctgct cctaatactt
     9781 tgaaagcacg gatttctgct ggtgtttcat aagttggacc agtcaagccc atataaacac
     9841 catcttctag tttgatgttc attttttcag ccacttcatg tgccttattg cgataaacct
     9901 tagtataggc atcagacata tcagggaagc gtggaccaaa ctcgttcaag ttttcaccga
     9961 ttagtgggtt atttccggtc atattgatat ggtctgtgat tgccatcaag gtacctgggc
    10021 cgtagccgat accaccagct gcatttgtga caagaacacc ttcacatcca agagctttca
    10081 taacacgaac agggaaagtc accacttcaa gcggatttcc ttcgtaaaaa tggaaacgtc
    10141 cttgtaaggc gagcacttta cggccagcta aatctccgta aactaacttt ccagcatggc
    10201 caacaaccgt tgacttgccc cagtttggaa tatctgcata atcaataaca atagcatttt
    10261 ctacttcttc agcaagttca ccaaggcctg aacccagaat taatccaaat tcgggagttt
    10321 caattccttt agtaactaaa aagtcttttg tttcgttaat tttagtcatc aatgacatct
    10381 ttttctcctt ttacctcaat agggttcaca ctctcgccat cctctttcat ataaggacta
    10441 ggcaggggaa caggaagaat atccagtaag gtctcagaag gacggcaaag ttttactcct
    10501 ttgcgagtca caacaatagg acgattgatc aaaattggat ccgccaacat ggcattaata
    10561 atgtctttct cagctactgc ttgatttgct aatccataag cctcaaattc aggaacattg
    10621 gttcgcaaga gttctcttgc agagattccc atcgattgta agagctcaat taaagtctcc
    10681 cgattaggtg gcgtctgcaa atactcaata atagtaggct caatacctgc atggcgaatc
    10741 atggcaagaa cattacgtga agtgccacag tttggattat gataaatcgt gatttcttcc
    10801 attatcaatt actaactttc ttattttaag tgactaagga atgactcccc aatcatggct
    10861 gtatcaactc caaaattttc tgcaacagtt gctgaaatat ccgcaaaatg cccttgtgga
    10921 ataagaccat ttccagtaaa ggatacagag taggcaagca atggaatgta ttcacgagtg
    10981 tggtcggtgc ctgcataggt tgggtcatta ccatggtcag cagtgatgag aagcaaatcg
    11041 tcttctttca tatttgcgat gatttcaggt aggcgattgt caaattcatg caagcagtcg
    11101 cgataaccct ctgggtcacg acgatgacca aagttggcat caaaatcaac gaggttagta
    11161 aaggagaatc ccttagtaaa ctcaggtaat tgaagagtct taataagcgt gtcaatacca
    11221 tggctgttcg acttattgtg tcccatgtcg tttataatac ctgaaccatt aaagatgtca
    11281 ttaatcttac caacggcata agttgggaca cctgcgtcag ccagtttgtt caaaacggta
    11341 tcttggaaag gagacactgc atagtcatga cggttagccg tacgtgtaaa gtttcctggt
    11401 tcgcctacat aaggacgcgc aataatacgg cctaaaaggg cagggcgttc aagcgtgatg
    11461 gagcgagcat attcacaaat cttgtaaagc tcttccacag gaataatgtc ttcatgggct
    11521 gcaatttgaa gcactgggtc tgctgaggtg taaacaatca actcacctgt ttccatttga
    11581 cgcggaccaa aatcatcaat aaccgcagtt cctgaataag gtttgttggc ctcgcgaatg
    11641 attttgcggc ctgagaattc ttcaatctta gttaaaatct cttctgggaa accattccag
    11701 aaagtgtcaa aaggttccgt aatgttcaag cccataattt cccaatggcc tgtcatggta
    11761 tcttttccaa gagatacttc ttccaatttg gtcacgtaac cagtaggatt gtcttctgtt
    11821 ggaacagttt ttagtggtat tggacgagaa atgtttccaa gtccaatttt tgccatattt
    11881 ggaaccgata agcctgctgc ttctgaaata tgaccgaggg tgtcagaatc tgtatcagct
    11941 acaccagcat taaagaattt gtcagcatct ggtgctgcac caataccgac agagtctaaa
    12001 acaaccaagt gaatacgatt aaattttgac ataagtctcc aatctagggg aggttacggt
    12061 tgactcccca atacctataa aatatattaa cgctgttata tgctaagact agcctgctgt
    12121 aggcgcttct aaaacagtaa cgccgtcttt actagcaaca atcaccttat caaccatacc
    12181 attaaagaga ccgtgttcca caacaccaac tgttccatct agcaggtgac caaaagcaac
    12241 aggatcttta atacaaccca aatcaagatc aataatatag ttttgcatgt ctgtcaccaa
    12301 acgactatca cctttcatac gaaaagacgg tttgtaacca gctttttcaa agacacggaa
    12361 caaacgatca gcaccatatt gaacgacttc gactggtaat ttaaaggcac ccagatgctc
    12421 taccatttta gaagcatcaa caacccagat gtattctttt gttggtgttg caacaatttt
    12481 ttccattagt aaggctgcgc caccaccctt gattccattg aaatccttat ccacttcatc
    12541 agcaccatct acggtgaggt caatgctatc aatatcatct atcgatttta aaggaatgcc
    12601 caagacttct gcttgcttgc tagtcacact tgacgtggtc acaccaacca cttgcagtcc
    12661 ttcttgcttt acgcgacggc caatttcctc aacaaaatag taagccgttg acccagttcc
    12721 aagcccaatt gtcatgccat cagtcacata ttgcgcagcg gtaacaccgg caattttttt
    12781 gagtgcttcc atgattcccc cttataatag aattgcgtct tagcacttta ttataccatg
    12841 aaagcgccaa cttgttaatg aaaacatttg tttttctctc attgacagtc taagtgctat
    12901 agaataggat gatcttttta aaacttatga tttattctaa agtcatcata taagcactta
    12961 ctttttgtgt ttatttagct ttttgaaaat caagtgtttt tgtttgacct ttactgacct
    13021 tttgattata ataatactat aagatgagta aaaataatgt ctgaatcatt ttattagcaa
    13081 agggtttcct atcatgtgaa atcctaacaa cgattctgcg actgcttaca aacatcttat
    13141 agtctatttt ttattgcgag gtaactgata tgacacattt ttctggtaaa gatccttttg
    13201 taaatatgga tgatattttc aaccaattaa tggcaaacat gggtggttat cgtagcgaaa
    13261 atccccgcta tctcgttaac ggtcgcgaaa taactcccga agaattccaa cactatcgtc
    13321 aaacaggaca actccctgta gcgacaacca aagcaacaaa ttctcaaatg ttaacaccta
    13381 aagctgatag tgtattgact caactcggaa ctaacttaac acaagaagct cgtcaagggc
    13441 atcttgaccc cgtcattggt cgtaacaaag aaattcaaga taccgctgaa atcttggcac
    13501 gacgaactaa aaataatcct gtccttgtcg gagatgctgg tgtcggtaaa actgcagtca
    13561 ttgaaggttt agctcaagcc attgttaatg gagatgtccc agctgctatt aaaaacaagg
    13621 aaatcgtatc aattgatatt tctagtcttg aagctggtac acagtatcgt ggttcctttg
    13681 aagagaccat tcaaaacttg attcaagaag taaaagaagc tgggaatatc atcttatttt
    13741 ttgatgaaat tcatcaaata gttggtgctg gtgccacaag cagtgattca ggctcaaagg
    13801 gacttgcaga tattcttaaa ccagccttgt cacgaggaga attaacactg attggtgcta
    13861 ctactcaaga cgaataccgc aatactattt taaaaaatgc tgctcttgct cgtcgcttta
    13921 atgaagttaa agtgaatgca ccatcagctg aagatacttt tcacatttta atgggtattc
    13981 gtaatcttta tgaacaacac caccatatta cccttcctga taatgttcta aaagctgctg
    14041 ttgattattc tattcaatac atcccacagc gtagcctgcc agataaagca attgacttac
    14101 tggatatgac agctgctcat ttagctgcgc aacacccggt cactgactta aaaacactcg
    14161 aaactgaaat agctaaacaa aaagagagtc aagaaaaagc tgtcgccaaa gaagactttg
    14221 aaaaagcttt agcagcaaaa acacggattg aaacattaca aaagcaaatt gagcaacata
    14281 accaaagcca aaatgtcact gctacagtca atgatatcgc agagtctgta gagcgcttaa
    14341 ctggtattcc tgtctctaac atggggacta atgatttaga aagactcaaa ggaattagca
    14401 gccgcttaaa aagccatgtc atcggacaag atgaggctgt cgcagcagta gcacgtgcta
    14461 ttcgacgaaa tcgggcaggt tttgatgatg gtaaacgtcc aataggttct ttcctttttg
    14521 tgggtccaac tggtgttggt aaaacagagt tagctaaaca attagcactt gatttatttg
    14581 gttccaaaga tgctattatt cgacttgata tgtccgaata taacgatcgc actgctgtgt
    14641 caaaattgat tgggacaacg gctggttatg ttggctacga tgataataat aataccctaa
    14701 ctgagcgtgt tcgtcgtaac ccttatgcta ttgtcttact agatgaaatt gaaaaagctg
    14761 atcctcaaat tattacactt cttctacaag tgttagatga tggacgattg acagatggac
    14821 aaggaaatac tattaacttt aaaaataccg ttattattgc tacatcaaat gccggttttg
    14881 gccaacaaga tacggaaact tctgagtcta acattatgga tcgcattgca ccttatttca
    14941 gaccagagtt tttgaaccgt tttaatagta tcattaaatt taatcatctg caaaaagaaa
    15001 gtttagaaga aattgttgat ttaatgctag ctgaagtaaa tcaaaccacc gcaaaaaaag
    15061 gtattagttt aacgattact gatgacgcta aagctcattt gatagattta gggtacaatc
    15121 acgctatggg agctcgtcca ttacgacgta ttatcgaaca ggaaattcgt gaccgtataa
    15181 ctgattatta tcttgaccat ccagaagtca aaaaacttca ggcaatccta aaagaaggac
    15241 aactagtgat taggcaaaac gatcagtaat aaacttcttc aattgaataa ttttcaaaac
    15301 atgaaaaaat ccgtcttgtg actacgttat acacttgacg gacttttttt tagcgctttt
    15361 ttaaaaataa ttttttcatc gcctaataac tcaagtttct ttccaaatct ggtgtaatca
    15421 aaataaccat taggtgtgag taatcctttt gaaaaagaag tatgtcccgc tgctacttct
    15481 tctttgatat caatggtgtg caaaatacga ttaacttttc ctttgagaac aacagcagat
    15541 aaatgtcctg ttttttgatt atatttgcct ccgatctgag aagctaattt ctcaaaagct
    15601 tgatctaaaa tcatttctaa ttcatggcta gctggcatac tattctcaat aatttggcgt
    15661 tctttactac tcaagtcacc aacaactaaa tgattttcct ttaatgtctt taataattca
    15721 ttttggtgat aagcagctaa acgtttgaca aaaatgtctc gttcaacttg aacactaaaa
    15781 ctcaagtcaa cgttgttatt tttaactgtt agtatcatct gagatgacgt taataaacta
    15841 tcatcaataa gagggctctg atgcaaacca gtaagacgtt tagcaaaatc atcgcctaac
    15901 ttctgatcaa tgcttgttgt tcgccagata ccttcaatag agctattacg atatcgaaca
    15961 ccaaaaagta cagcaagcaa gataagaaaa ataataaata caaaaagggc attgcattga
    16021 tggcataaca atgactttcc tttagagcgc ccttgggcta cttgtgtcat gactcatctc
    16081 cttaatataa aatactagca tgtcatcatt aaggcgtcaa gtaaaatcgg taaacctaac
    16141 tatgattttt tatgttttcg ataagaaaaa caccctctac tgagaatgtt ttagcataga
    16201 taaatcaaca cctatcgcta gacctgctct aaaatagcat cccaagaatc atcgatacca
    16261 atacgttcta ccgaagaaaa tactataaaa gtatcagatt tgtcaaaatt caaagctttc
    16321 ttgaccacag actcatgttt gttccatttg ccacgaggaa tcttatctgc tttggttgcc
    16381 acaacaataa caggaatgtc atagtacttc aaaaagtcat acatctgaat atcttctttt
    16441 gaaggggcat gacgtaaatc aaccaaactc acgactgcac gcagattgtc tctgctggtt
    16501 aagtattctt cgatcatctt tccccatttg gcccgttcac ttttagaaac cttggcatag
    16561 ccataaccag ggacatccac aaatctaagc ttgttatcaa tattgaaaaa atttaatagt
    16621 tgggtttttc ctggcttgct tgaggttctt gccaaatttt tgcgccccaa tatggtatta
    16681 ataaaacttg atttaccaac atttgaacgt ccagcaaggg caatttctgg caaatcatct
    16741 tgggggtaat gagatttatt ggcagcgctc aataaaattg aggcgttatg ggtatttaag
    16801 acttgttctt cagccattat ttctccttaa gctgtctcta aaacgggttt tgacttgcct
    16861 tcgacagcag ccttggtgat acgcactttt gtgacatctt cttggcttgg aatttcaaac
    16921 ataatgtcta acatcgtttc ttcaataata gaacgaagac cacgtgctcc tgttttacgt
    16981 tcaatggctt tattggcaat ggcttctaag gcttccttat caaatgccaa ttcgacgcca
    17041 tcgtaagaaa gaagggcctg atattgcttg accagggcat ttcttggttc tgtcaaaatt
    17101 tgaatcaaat ctgatgtgtt tagttgttca agggctgcca caactggtaa gcggccaata
    17161 aattctggaa taagcccaaa cttttgaata tcttctgaaa taatttcttg catataagaa
    17221 gcattgtcat caattttacg gctgttttga ccaaaaccaa taactttttc acctaaacgt
    17281 tgtttaacaa tctcctcgat gccatcaaaa gccccgccaa caataaacaa gatatttttt
    17341 gtatcaattt ggatcatttc ttgattaggg tgcttccgcc caccttgtgg gggaacactt
    17401 gctaccgtac cttcaataat tttaagaagg gcttgctgta caccttcacc agatacatca
    17461 cgtgtgatag atacgttctc acctttttta gcaatcttat ctatttcatc aacataaata
    17521 ataccacgct ctgctcgttc gacattatag tcagcagcct gaatcagttt gagtaaaata
    17581 ttttccacat cttctccaac ataccctgct tcagtcaaag aagttgcatc tgcaatagca
    17641 aatggtacat tgaggctttt agccagagtt tgtgctaaga aggtttttcc tgaacctgtt
    17701 ggtccaatca tcaaaatgtt ggacttttgt aaatccacat catcgtcatc acgactttct
    17761 gtaaacgaga cacgcttata atgattgtac acagcaactg ataaagcacg tttagcacga
    17821 tcttgaccaa ccacatattg atttaaaaca tcaaggagct cttttggttt tggaacttct
    17881 gtcaaatcgg caaggacttc ttcagccaat tcttctttta taatttcttg tgataaagct
    17941 acgcattcat tgcagatgaa aacattattt cctgcgataa tttttttaac gtcatcctgg
    18001 cttttaccac aaaatgaaca gtatacttta atatcgttag ttctacttcc tgccatttct
    18061 tataattctc ttactttctc ttatctttta ctgaatttta atattagtca atgtgttgta
    18121 ttggtttttg gtgattcttg cttgatagct aaatcttcac cagtgctgtc tttgcaagtc
    18181 gcatctcaaa acaatgtacc atagaaggcg tgaatactat taaccagatt agtaaacgca
    18241 tttaataaga acagacttgc taagccataa cgattctttt taaaagctgg gatggcacaa
    18301 agaacacaaa tcacgcacaa aaaagccgta aatactccaa aaatactacg ttgcatcgct
    18361 tatcatctcc tcagactatt tgtgttttaa agcagtaacg gtaaaatcat aaggattttt
    18421 agcgtctcga gcatagaacg tttggctttc ttgcgtgaaa tgactaaaat ctagatttgg
    18481 tcggtaggta tctcctttaa aacgatgatg gataactgtt tttatgatac gatcgaaata
    18541 accattaaac gcttctaaaa ccttattccc accaatgata taaagtgttt tatcctgcgc
    18601 atggtaccac tccaagactt tttcaatact agtcattgtc aacacctcat ctacttgata
    18661 atctctattt cttgtcatga caagggtttg acgttgagga agtcttttgc aattcattcc
    18721 ttcaaaagtc acacggccca ttaagattgc ttgatgtagc gttgtctttt taaaatgttc
    18781 taactctttt ggtaaatacc atggtaactt acccgcaaca ccaataagcc ctgcttcatc
    18841 ctctgcccaa atagcaataa tttcctttgt cattaattat ttccttcatt ttaaactcta
    18901 tttattttac caaatttatg aacaaaatgc tcacaaaaaa tctaaataaa gtttaaatag
    18961 caaggtcaaa gtgcaactga ggcttcactg gatcataatt ttgtaattca aaatcatctg
    19021 gtttaatatc aaagaaatta gtcccatctg gaacatttaa aacaagctta ggctgactgg
    19081 caactggctg tcgttttagt aattcttgag cctgatcaaa ttggttgtca taaatatgta
    19141 aattgttaac aaaataaaag aacttaccta ttttccatcc aaaatgttta gcaatcatca
    19201 tctgcaaggc aacgtattgc atggcattga tgtgatgagc aactaatatg tcattagaac
    19261 gttgcgtcaa actagcatct aaataaagat cttcccctac acgtctaaca tcaaacatga
    19321 tttgaaaggc acatggcaac aacccttttg tctcctcaaa tgcttcatag tcccagagag
    19381 aaatgacatt acgacgattc caaggatttt ctgctaattg ctttagtatt tttgagatga
    19441 tatcatgttt tttgactaca gcaccataac gttgcccaat agtacgtgtc tggtcaactt
    19501 cccattcatt ccaataatga acattatatt tagcttctag cacatctaaa ctgttagact
    19561 gatcttgata tatccaaaat aattccttta tagcagattt aattggaata ggtcgtaaag
    19621 ttgtgatggg aaactctcct ttagctaaat catattcagc aaacgcccca gtaatatact
    19681 tagaatgagc tgttcgacca tctttatatt taggacgtgc ttgctcactc aatgatcctt
    19741 catttataat tttttgaata ttagctttaa aaatctggtc agcttttgtc atctctaata
    19801 acctttctgt aagcatactt catactattc taactaattt taccaaaaaa taccagaata
    19861 aataaacatt cgaaaaactt catgtggtca tgaacatttt aactattaaa ggataaaaca
    19921 aataacttta tcagtctaat tttgcagtaa aatgtgatag aatgggtaag actataaaaa
    19981 taactaaaag aaggacaaat atgacaattg gaattgataa gattggtttt gcaaccagtc
    20041 aatatgtctt gaaattggaa gatttagcgc ttgcacgcca agtggatcca gcaaaattta
    20101 gtcaagggct actcattgaa tcttttagtg tggcaccaat cactgaagac attattactt
    20161 tagctgcttc tgcagcagat caaatcttaa ctgacgaaga tcgagctaag attgatatgg
    20221 ttattttggc aactgaatcg agtactgatc agtcaaaggc atcagctatc tatgtacatc
    20281 acttagttgg tatccagcct tttgcacgtt cctttgaagt aaaacaagcc tgctatagcg
    20341 caactgctgc tctagactat gctaaactgc atgtggcttc taagccagat tctcgtgtcc
    20401 ttgttattgc tagtgatatt gctagatacg gtgtaggatc tcctggcgaa tcaactcaag
    20461 gatctggtag tattgctatt ttggtaactg ctgaccctcg tattcttgct ctaaatgaag
    20521 ataatgtggc tcaaactagg gatattatgg acttttggag gcctaactat agtttcacac
    20581 cttatgttga tggtatttac tctaccaagc aatatctcaa ttgcttagaa accacgtggc
    20641 aagcttatca gaaaagagaa aaccttcagt tatctgattt tgctgcagtt tgtttccata
    20701 ttccatttcc caagttagcc ctaaaaggtc taaataacat tatggataac acagtacctc
    20761 ctgaacacag ggaaaaacta atagaagcct ttcaagcttc tattacttat agcaaacaaa
    20821 ttggaaatat ttatactggc tcactttatc taggattgtt atctttactt gaaaatagta
    20881 aagtattaca atctggagat aaaattggtt tttttagcta tggttccggt gccgtaagtg
    20941 aattttattc cggtcagtta gttgctgggt acgataaaat gttaatgact aatcgacaag
    21001 ctttactgga tcaacgaaca cgtctttccg tttctaaata cgaagacctt ttctacgaac
    21061 aagtccaatt agatgataat ggtaatgcca attttgacat ttacttaact ggaaaatttg
    21121 ctctaacagc catcaaggag catcgaagga tctatcatac caatgacaaa aactaatctt
    21181 aactggagcg gtttttcaaa gaaaacattc gaagaacgcc tccaacttat cgaaaaattt
    21241 aaactactta atgctgaaaa cttaaatcaa ctcaaaacag acgttctttt gcctatccaa
    21301 acagctaatc aaatgactga aaatgtctta ggacgattgg ctttgccctt tagcatagct
    21361 cctgattttc ttgtcaacgg ttcaacttat cagatgcctt ttgtcacgga agaaccttct
    21421 gttgttgctg cagcatcttt cgcagcaaaa ctaatcaaac gctcaggtgg ttttaaagct
    21481 caaaccctaa accgacaaat gattggtcaa attgttcttt acgatatcga ccaaatagat
    21541 aacgctaaag ccgccatcct ccataaaaca aaaaagctaa ttgcattggc aaataaagct
    21601 tatccttcca ttgttaaaag aggtggaggc gctagaacca ttcatttgga agaaaaagga
    21661 gagtttttga ttttctatct gactgttgat acccaagaag ctatgggagc aaatatggtc
    21721 aatactatga tggaagctct tgttcctgat ttaacaagac tgtctaaggg gcattgtcta
    21781 atggcgattt tatctaatta cgcaacagag tcgcttgtta ctactagttg tgagattccc
    21841 gtgcgccttt tagatcgcga taaaacaaaa tccctacagt tagctcaaaa aatagagcta
    21901 gccagccgac tagctcaagt agatccttac cgggctacta ctcataataa aggtattttt
    21961 aatggtattg atgcagtggt aatagccaca ggaaatgact ggcgtgctat tgaagcaggg
    22021 gcccatgctt atgcctcaag aaatggtagc tatcaaggac ttagtcagtg gcattttgac
    22081 caagataaac aagttctgct tggccaaatg accctcccta tgcctattgc tagtaagggg
    22141 ggatctatcg ggcttaaccc tactgtttct atcgcacatg atcttcttaa tcaacctgat
    22201 gccaaaacat tagcccaatt gattgcatct gtggggttag ctcaaaactt tgctgcacta
    22261 aaagctctga cctcatctgg catccaagct ggtcacatga aactacatgc gaaatcatta
    22321 gctcttttgg cgggggcaac ccaagacgaa attgctcctt tagttaatgc tttactagct
    22381 gataaaccaa taaatctaga aaaagcacat ttttacttat cccagctaag acagtcttag
    22441 atttaaacaa ctaatataag gcaaacaccc atgtaaacaa ttggtttaca tgggtgttta
    22501 atctttgttt ctatacatac aagtcttaga aatagtctcc ataacatact ctatttactc
    22561 atctactcta ttctgagttt gatgaggtat ttataaatat tttatattat gttctaaaaa
    22621 agctctatca tctttgtagt aggtgacact attgtagagg tgatgaagcc taattgacct
    22681 gctgcaagcg tccatatagt aagtagtcga ctccctttaa ttctttaata gttttacagt
    22741 caagagcaca cataatgatt tttaattctt ctttccagcc attaacgata gcaatcacac
    22801 gctcggttgg gtatttttcg accaattcta aaacggtgcg tgagagtccc actgcacgtg
    22861 ctcctaagac aaaacactta atcatgtcca aggggtgtct gacaccaccc gaagctaaga
    22921 tttccacttg gtccatcagt ccttgtgcat tcagtaagca ctgaacagtg gtttgtcccc
    22981 aatcgtttaa gtaagagcgg tctccccctc tttgattttc aatgtaagca aatgaagttc
    23041 ctcctctacc tgaaatatca aaggtttgaa tgcctaggtc atgtgctagc ttgatactat
    23101 tgacatccat gccaaaacca acttctttga gaatgacagg aactggtatt tgactagcgt
    23161 attcagcgag gtgttttttc caggtatgaa agacgcgctc accctctggc atcagcaact
    23221 cttgcatcac attcacatga acctgtaaaa agaggggctg catttcttga accgtttgtt
    23281 gtcctagcgc cacaggttta tctagaccaa tattcgtggc tagtttcaag ttatctgcca
    23341 cctcatgtaa acgataggaa tcgtcgttag gattttttaa agcagcgcta taagaccctg
    23401 tcaccatgac aatccctgtt gctgctgcta ctttggccaa tttttcattg acagctttgc
    23461 ctttttgact tcctcctgtc atggcattga tgtaaaaggg aaagtcgaag tcttgcccag
    23521 caaaatgagt actgagatca atatcagaca aatcatagct aggtaaggaa tggtgtatga
    23581 gttctatgtc atcaaaagca ttataaggcg attggtactt gagagcatat ttgatgtgat
    23641 catctttacg gttagtcatt ctctccccac ctttcttgat aaagtaatgc gatatcagct
    23701 tcttgccatt tggaaataag ggtatctcta gcatcctgat taaaggcaag cgcgatgcca
    23761 caatctccac caccagaacc tgaagattta acaacagcat cttgcttctg acaagcagct
    23821 accaaggtta ctagcttagg atggtagata gctggatgaa gctcttttag gagatgactt
    23881 gctcctgcta aacttttctt gagttcttcc ttatgacctt cttgcaaagc taccatagct
    23941 gattgcgtta gctggtaact tgttcttaag aaagctgggg taatgctcgc tgtcacttgt
    24001 tgaatcatct gccttgaaat agcaggtatt ttagtccagc caaccaaaaa gtcacaaggc
    24061 agggctggtt gaatgacttg gatatggtaa ccccaatctt tgacgagaag tttttttaag
    24121 ggcatggtct gcagccagtt actgacctgt tctcggtcaa aggaggtata ggcgactaaa
    24181 gtctggtaag cgatacaggc aatatccccc atagacccat tatctccttg cttaagcaag
    24241 gtataagccg ctagtttaaa gagtaactct ggggttaaag tgatctgata ataggccgat
    24301 aaggccttta aggttaagag ggtgacgcta ccacttgaac caatgccaaa ttttttgcca
    24361 tcgcgctcca tttttcctgt tacgattagg gaaaatggct ccagttggtc aatcgactgt
    24421 cctagatagt cagcaaaggt tttaaccgtt gcttgaatca gtgcataaga ggcatcgggt
    24481 gtcatgcccg ctttatgggc aaacatatct gaagctaatt gaatatgggc tgctgggcta
    24541 atttctgctg tcatcatcag tggaataaag tgaattaagg ctttttgtcc tggtgttaag
    24601 atagcatatt cgcctgtgag gtatagtttc ccacctgttt gcacacaata attagacatc
    24661 tggtaaatcc tttgtttttg aaacgataat acggtagttc ttgccaagtc gttctgccag
    24721 ttgagccaag tctttttcta aacataggac cttcacgttt ggacctgcgt ccatggtaaa
    24781 ataacaagca aaaccttctt gacgcagttc tttcacagcc tccatagcct ggtaagactc
    24841 ttttgttagg taagaaaaag gaggattggc tgtctttgtc gtggcatgca tggccaaggc
    24901 attagcttct gttaactgac caactttctc aaaattatta gttttgagat aggtaagcat
    24961 atgttggtaa tcgattgccg attgttctac ccactcatca aatgtagttg aggtatcgcg
    25021 gcataacttc atgccctctc ggctagaaat tggctttttc gcagcattta agaccagcat
    25081 aatcatggcc attttcaagt cagtctcaac cttgtaaata gcaccactat ctttgtccca
    25141 agcagcgact gggccaaaaa aagaacgaga agatgatcct gaggcgaact tagccttttg
    25201 agctaaagct ttctgatcta gctgggtgtt aaatagttgg tcacaggctt taaccaaggc
    25261 tgataagcca ctggaacttg atgataaacc tgcagctgtt ggcatattat tttgagtttc
    25321 catctttaca aaagcctgac caggttggcg aaattggtca atgatagcag aaattttggt
    25381 atgttcttcg tcattttgca agacaccgtt aatgtaaaac tgatcactgg ttgcagtatc
    25441 tggtaagaag gaaatgctgg ttgtggtgaa catgttttcc aaagtcaaag aaatgctaga
    25501 ggtcgaagga atcatcttag cttgattctc ttttccccaa tatttgataa tagcaatgtt
    25561 agcataggat gttacggtta taacatttgg atccacgtgt ttacggctcc ttcttctttt
    25621 aatctgtgac tgattttttc ggccatgtct ttggtatctg ctagggcaat catacagcca
    25681 cccaagccac cgcctgtcat cttagcgcct aaagcacctg ctcttagggc agcctccaca
    25741 agttggtcag ccttactgat gctaacgcca atggccttta aagcagagtg cgcttgtgtc
    25801 atgagctgac cgatagcaac cttatttttt tggttaatcg ctctttcaag ggcttgtgtc
    25861 aaagctccta gtttagccag atagggcaaa ttcgtttcct caaactgtgc taccttattg
    25921 acggcctcac gtgtatgacc gtgaatccct gtatctgcaa tgataagata accatttaag
    25981 gcgatttcga tagtttcaaa gccaatgttt cggataaact taatggcatg gtcactaagg
    26041 catgtcttgg catctaaacc actaggattg gtgtgggcaa taatttctgc cttgttgact
    26101 aaaatttcca acaaatcatc cgagaggggt tcttgacaat aagaaaaaac ggatctaata
    26161 gctgcaatag aaacggctgc cgaagacccc ataccacgct tttgtggcac ttgtgaaaca
    26221 atctcataag caattggttc ttgtagtcgc tgcaaataat ccaaggcagc ataaatggct
    26281 gttgatagag tatcataaaa atcaaagacc aatggcttat cagctggaaa aatatgacaa
    26341 accacctcaa tatctgttaa aggcaaagca atagctgggt agccatacac aacagcatgc
    26401 tcacctatca aaatgatctt actgtgtgcc ttaccatatc caatgttttc gttcattttt
    26461 tatcttttca ttactaattc ttctaaactt ttaccttact attttacact aaatgattag
    26521 aaaatgcgat gatatatctt tttaaaatca tttcttcacc gaaattaaca ataaagacta
    26581 tctactcttt ttaggatcat aacaaaaatt ttcttatttc aaactacctt ctttaatcac
    26641 tcttctacta aattaaacgt taaaaaccag cctcatgggc tggttaagca tcgtttatta
    26701 cctttaccta gacattatta ctagctaaag gtactgaaaa atgtttaagt caaatcacca
    26761 ctgtaaaaac aatagcatcg tttttataat ttacagttat cgttccttta aataacttaa
    26821 ccatactttc tgccatagat aaaccaattc cataaccttt ttctttgcta ttatgggatt
    26881 cgtcttcgcg ataaaagcgt tcaaaaaagc ggctgtaatc aatggatttt ccttccaaat
    26941 aggtattaga aacttctaat ttcgctcgtt ttcgtcttct tccaatagtg gttaaagata
    27001 ccttgaccaa gcctttagga tcacaatatt tattggcatt atcaactaaa attgtcacaa
    27061 gttcaaataa tgacttttcc tccgctttaa tcataatatt cggctgaatc gtcaaatcaa
    27121 aacgtttacc atctttcaaa accagactct taaaatcttc agctgcatct tgagcaatag
    27181 ctgaaaagtc taccatatgt aataccacat ctggctgttc ctccaaacga gccaaagtaa
    27241 tcatttgatt aatcaagcct gtcaatcgct tcacctgatc acttgtactc ttggtccatt
    27301 ctgattctcc agtcattaat tcgaccaatt cattattggc tgagataatg gctagtggtg
    27361 tttttaactc gtggcctgca ttagtaataa agcgacgctg cttctcataa ttttggacaa
    27421 aaggtttgat gaccataccg gaaaaaagac tcactaaaac aacaaaaaag ataaatcctc
    27481 caaaggccaa catcattgaa acagctaata aatctcctac actacgaaaa taaaaggtag
    27541 tatctaaaat tacaaccagt ttttcttcat ttggcagctg agtaatcaag tacgaataaa
    27601 cactatcttg gtgacggtaa ctgccttttt cttccccaga cttagcaaaa agtctagcaa
    27661 aatattgggc ttcttctcta tctaaagctg aaatattagc agtattagaa gaaagtagat
    27721 gtccattagc attaaaaatg acactataat accgaaactg gcttaggcta tcttcagaca
    27781 gtttcgttcc aagtcgttta gagctttccg tagtgtcagg taatttacct ttatttgagg
    27841 aaattaaatg taaaatacgg ttaatttctt gttgactttg gtaacagcgt gccgtgttaa
    27901 taataccaac aattgaactt aaaataataa aaatggcaat agaagcaatc atgataaaac
    27961 gaatacggat acgattaaac atgtcacctc ctatttttct aataaacaat agctagtatc
    28021 tttatcacct gcaataatga catttgcttg aatagctaat aatttttgac gaagataaga
    28081 aatataaacc caaacaatag aagtatcata atcttcttgg tctgaccaaa catgttggta
    28141 aagtgtttta gtatccaagt actttccttg atttaacatt aaaaaggcca ttaatttacc
    28201 ttctttagaa gctaatcgta tagcattacc ggcactcaat tcttgctcat taatatttaa
    28261 tgtgacacca gcaaattgta atacctgagg agtaaaactt tctactcgtc tttccatcga
    28321 ccttaatcta gctaaaagtt cttttaatga gaaaggttta gtcagataat catcagctcc
    28381 cgcatctagt ccggtaacac ggtcgttaat ttctgccata gccgtcagca taataatatg
    28441 tgagcaattt cctgaagcgc gaatctcctt taaagcctca atgccagact taatcggcat
    28501 catgatatct aaaatcataa tatcatatgc attgtctttg gctttatcaa ttgcctcttg
    28561 accgttaaaa accacatcaa cgtcataacc ttgatgagtc atggcagttg tcaaaacatt
    28621 agacatctgc cattcgtctt cagctaacaa aattttcatg gttactcttc ctccgtcgtt
    28681 tcttgaatca attgacgaat ggtttgcatg gtaacatcac aagatgccaa ctcgtctgca
    28741 caacgcttta actctcttgt aatcatttct gcattagcaa cttgatgttt gtacttcatt
    28801 tgatgttcca agctagccca agagtcttga gcaatggttc gcaactgcac ttctataaaa
    28861 taacatcctt ttttttcccc taaaatatct ggaaaatgtg tttctaattc caaaatgaga
    28921 tgatatgatc tatagccatt aggcttggca tttaaaatat aatctttttc agcgttaact
    28981 gacataccag gaatgctttt gagcaagtct accatccgat aaatatcatc aataaaacca
    29041 caaataatgc gaataccgat actatcttta atgattttta acgcagattt gcttgttaga
    29101 ggaagctgtt tgcgttgaca tttttcaatc atcgaagctt ccgatttaat acgggatgta
    29161 aagtgttcgt atagtttaaa ccccgtttct tttttgcttt tgatattctc agcaataatc
    29221 acatctgtta ttgtctgtag taccaacggc aagtacactt caaatccgct atatatagag
    29281 ctggtagaat aatgttctag tctttctttc atacgcttat tataacaaat tttctcaaca
    29341 aatgcttaaa tctctgcaat gatcggttat ctttatttct aactatataa cttcaaatga
    29401 tctgcatcgt ttgtttttaa atcgctttca tatatttttt gtacgttgtt ttttaaaaat
    29461 accattgaat tacaaacaaa atcatagtaa acttgatcta taacgattac gttaacttat
    29521 taggagattt tatgaaaaaa tattttattt taaaaagtag tgtattgagt atcctgacta
    29581 gttttactct attagttaca gatgttcaag cagatcaagt tgatgtgcaa ttccttggcg
    29641 tcaatgattt tcacggcgct cttgataata ccggaacagc ttacacacca agtggtaaaa
    29701 taccaaatgc tgggacggct gctcaattag gtgcttatat ggatgacgct gagatagact
    29761 tcaagcaagc aaatcaagac ggaacaagta tacgtgttca agctggagat atggtcagag
    29821 ccagtcctgc taactctgca cttttacaag atgagcctac tgtgaaagtc tttaacaaaa
    29881 tgaaatttga atatggcact cttggtaatc atgaatttga cgaaggacta gatgaattta
    29941 accgtatcat gacaggtcaa gcgcctgatc ctgaatcaac aattaatgat atcaccaaac
    30001 aatatgagca cgaagcttcg catcaaacca tcgtcattgc taatgtcatt gataaaaaaa
    30061 ctaatgatat cccctatggt tggaaacctt atgctataaa agacatagcc attaatgaca
    30121 aaatcgttaa gattggcttc attggtgttg tgactacaga gattccaaat ctcgttttaa
    30181 agcaaaacta tgaacactat caatttttag atgtagctga aaccattgcc aaatatgcta
    30241 aagaactgca agaacaacat gttcatgcta ttgtggtttt agctcatgtt cctgcaacaa
    30301 gtaaagatgg tgttgttgat catgaaatgg ctacggttat ggaaaaagtg aaccaaatct
    30361 atcccgaaca tagcattgat attatttttg caggacataa tcatcaatac actaatggaa
    30421 ctatcggtaa aacacgtatc gttcaagccc tctctcaagg aaaagcttat gcagatgtcc
    30481 gtggtacgct agatactgat accaatgatt ttattaaaac tccatcagca aatgttgttg
    30541 ctgtagcacc aggtatcaaa acagaaaatt cagatatcaa agctataata aatcatgcta
    30601 atgatattgt taaaacagtt actgaacgaa aaatcggaac tgcaactaat tcttcaacta
    30661 tttctaaaac agaaaatatt gataaagaat ctcctgtcgg taacttagta acaacggctc
    30721 agcttactat tgctaagaaa acttttccaa ctgttgactt tgctatgacc aataatggtg
    30781 gtattcgaag tgacctagtt gtcaaaaatg accggaccat cacctgggga gctgcacagg
    30841 ctgtacaacc atttggtaat atccttcaag tcattcaaat gactggtcaa cacatttacg
    30901 atgtcctaaa tcagcaatac gatgaaaacc agacctattt tcttcaaatg tcaggtttaa
    30961 catacactta tacagataat gatcctaaga actctgatac ccccttcaag atagttaagg
    31021 tttataaaga caatggtgaa gaaattaact taacaactac ttacaccgtt gttgtcaacg
    31081 actttcttta tggtggtggt gatggctttt cagcatttaa aaaagctaaa ttaatcggag
    31141 ctattaacac agatactgaa gctttcatca catatatcac aaatttagaa gcatcaggta
    31201 aaactgttaa tgctactata aaaggggtta aaaattatgt aacttcaaac cttgaaagct
    31261 cgacaaaagt taatagtgct ggtaaacaca gtatcattag taaggttttt agaaatcgtg
    31321 atggcaatat agtgtctagt gaaatcattt cagacctttt gacttctact gaaaacacta
    31381 ataacagcct tggcaaaaaa gaaacaacga caaacaaaaa tactatctct agttccactc
    31441 ttccaataac aggggacaat tataaaatgt ctcctattat gacaatcctt gccttgataa
    31501 gcttaggtgg actaaacgct tttattaaaa aaaggaaatc ctagcgttta ctagtaatcg
    31561 atcaccctta tataatcagg catctttgcc aaaaaaccta aagcgtccta ctctaggttt
    31621 tttgttaaat taaaatacct tctagatgat ctaattcgtg ctggcatatt tgagcagtta
    31681 agcctgttaa gcttaatcgc tttggtcgcc aattatggtc caaatactca acagtaatct
    31741 tatcataccg ctgtgttttg cgatagccag ataacgacaa acaagattct ttagtttggt
    31801 aaattccctt tttagaaacc atcacaggat taaacataac caaatcaata aatcccatac
    31861 tcacaataac aatgcgtttt tgttcaccaa tcatattggc agccatccca agacattcct
    31921 gtctataaaa ggctaaggta tcttgtaaat cttggccaat ccatagatct tctttcttgg
    31981 cgacttgcgc tttttgctgt aataaaaaat gatctgttat gatttctcta atcattctta
    32041 tctccttaaa ccttcttttt aattcataaa ctacatgttc aatggactat tatcaccata
    32101 ggatagactt agtatcatct gtttaaaaca tcaggtgatt ccttatttca agataccttg
    32161 ggcaacttta tgaaattctg caatatgagt accaaataaa aattgacctg catcagcaga
    32221 ttgttgctaa gttctcatca caatattatc gaatttactg tctgcttctt caaatgtcta
    32281 agagagatag ttattgcttt gtgagatttt caaaccagat actgctttct cttgcatttg
    32341 cagccttaac aggtccaaat aaaacacctg ctgtttgaaa tgctttaata actgatatat
    32401 tgttaatagt tagtattata aattttctga atatttctgt caagtttttc agttgactta
    32461 acttttttac ttgatttttc ctcacgtaat aatagaaaag aagcgccata atgtaaacta
    32521 caccccaaac gttagataaa aaatctaacg tttggggtgt ttttgcatga cattaagcta
    32581 tgaagataag ctagatattt agtgctaaaa aaaccgaggg aactccgttt gaaagaagca
    32641 tctctgaaaa aaaaccatta caaagaatgg acaaagacga gttctgatta gattttcttt
    32701 taagaacggc taaattgact cgttctacct actattatca tcgattattg caacaataaa
    32761 cgtatcaaaa taaaacgaaa aggacttagt cctctacaac acagaactaa atcctttact
    32821 tcaaatagag tagccaactt ttggggctca gtgcaagagc acttcttttc tattatcact
    32881 tgtttattat aaacataaca ttaccatagt atacttatat gtctagtcca ctcaaatact
    32941 caaaccgttc atacgccaat aataaatcat tattgcgctg atcgagttcc ttttgtaatt
    33001 gagctaactg gccataatca ctaactacag ttaacatttg gttttcaatt tcttcaatat
    33061 tagcctcaat agttgctatt ttatcttcta tctgagccca ttcttgtttt tcaaggtagg
    33121 acatgcgctt tttctcctct ttcggaggaa gtggcacttc ttcagtgact attgctttag
    33181 ctaagtcagc ctcaactgtt tctttttcaa aagctttttc atcaaggtaa tcactgtaat
    33241 tcccataaaa aacacgaata tcgccttctt caaaggctaa aatcttagtg gctactttgt
    33301 ctaggaaata acgatcgtga ctaaccgtaa tgactggtcc tgcaaagtta gccaaaaagt
    33361 tttctaagac cgtcaaggtg gcaatgtcta aatcatttgt tggctcatca aggagaagaa
    33421 catttggctt ttcaatgagc agttttagca agtagagccg ttttttctcc ccaccagata
    33481 atttagcaat cagcgtgcca tgacttgatc tcggaaaaag aaattgttct aaaagctcac
    33541 tgatactcgt tgttcccacg cttgttttaa cctcatcagc cacttcttga aggtaattaa
    33601 tgacccgttt ggtctcatcc atatctttga gctgctgaga gaaataacct acacgaatag
    33661 tatctccaat atcaagcttc ccagaagttg gtttgagatc accgttgatg atatttaaca
    33721 gggtagattt tccgacgccg ttatctccaa caattccaat acgatcttta ttttgaataa
    33781 tcaaattaaa atccttaatc aactgtcggt cgccataagc aaaagaaagg tcttcaaagt
    33841 gaatcacctt cttcccaatt cggctcgttt cgaaagccat ctccaactta tccgcagaac
    33901 tgtcttggtg aacttctttt ttcaagtcag tgaaacgatt gattctagcc tgctgtttgg
    33961 ttgcacgcgc ctgtggctgc gtcctcatcc aggctaattc ttgtttatag agttgcttct
    34021 tcttgtgtaa attagcagca tctcgttcgt cttgttctgc ttttaagcgc acatagtctt
    34081 ggtaattgcc ttgatattct gtcagtccag ctttatccaa ttcaaaaata cggttagcca
    34141 catgatcaag gaaataacgg tcatgggtaa taaaaaggac ggttttttta gctgtcttga
    34201 gataggttgt taaccaagcg atggtatcaa tatcgagatg gttggtcggc tcatctaata
    34261 ggagtaagtc agcagctcct agcaatactt gagctagctg gacacgtctt ctcataccac
    34321 ctgatagatc tcccactttt tgttccaaat ccgtgatgcc taattttgat aggactgttt
    34381 tgacatcact ttcaatagac caagcatcta agcgatccat ttcagacatg agggactcta
    34441 aggtctcttg tttatcttca gtataattcg ccatcaatag ttcatactga cgaatcagct
    34501 gaatcgcctt aacatcagat gacaataccg tatctaaaac agaggctgca tcgttaaatt
    34561 caggatcttg tgttaagtaa gcgattttgt aatcattggc tttagaaaat ggtgaatggt
    34621 ctccgtcaaa accaagcctt tccgacaaga catctaaaag agttgttttt cctgttccat
    34681 taaccccaat aatcccaata cggtcaaagt catgaataat aaaggaaata tcctgaaaga
    34741 ctgttttatc tcccaccgtt tttgtcaatt tctccaccaa aaaatggctc atgttgctaa
    34801 ttcctctcta acaaatgctt caattgtagt gaaatcatta tctaggcgtc cctctacaat
    34861 cgctaattca actttctcaa gcataagccc tagctgagga cctggtttca tcccaaaatc
    34921 cttaatcagg tgagaaccat taaggacgat atcgtatttg ttatgaatgg ctagcgcttg
    34981 atctaaagct tcaatgtggt ccatgtcaac agataagctt tgagcttttc ggaggccttc
    35041 cactagactt gccatttcct tgccgtactg gtaaatatcc aatttttcaa aagatctttc
    35101 ctgacgaatt ctataaagag caatcaactt tgtgacataa cgctgaaaat catttgaagt
    35161 cttccatgct tttaggaagc ttttaggatc ctcaatggct aaactaatca tcacataagc
    35221 ccaagcttgg tgatgatcac taaaggtaaa gttatctttc aaagaaacta tcagatgatt
    35281 caagcctgct tcctgctgct tcaagcctgg taaatagtca taagcctgac aagcaatcat
    35341 ggcagaaatc ccttttcgcc agtgcggtgc catcaataat ttatcaaatt cagtaaaaga
    35401 acgttccaca gaaatctttt ccaatagagg tgaatggctc ctcatagctt caaaagttgc
    35461 agcttcaatg tcaaaatcca gactcgccgc aaatcgaaag cctctcataa tgcgtagtgc
    35521 atcttcttca aaacgttcct ctgctttacc cactgctcgt aaccgttttt gctttaaatc
    35581 aatgagtcct ctaaatttat caataacttg accattttca tccaaggcca aggcattgac
    35641 ggtaaagtct cttcgtttta agtcttcctc taaagagcgc acaaaagaaa cctgactagg
    35701 acggcgataa tcaacataga catcttctgt cctaaaggtt gtaatttcat attcaccacc
    35761 attttccaaa accaaaacag tgccatgttc aatgccaaca tcgacagttc tgttaaaaat
    35821 cgctttagtc tcttcaggat aggaactagt tgcaatatct acatcatgaa tgggacgctc
    35881 gagtaaaaca tctctaacgc ttcctcccac aaagtaggct tcataaccag cttcttttat
    35941 tttagtcaat atgggtaaag ccttctgaaa ctcagaaggc attgtcatta atttcatacg
    36001 ttgttttcta acctatcatc caactagccc aatctaaagt gtgattaggc tacttgggtt
    36061 ctatcacatt ttgttattgt tttagtgatt cttgcaatta actatttttt ctaatcgaca
    36121 attaaagcct cggtgttacg ccaaatgcaa tggctccttc tcctaaatga gtagcaatca
    36181 ccgctccaaa atgaacctct tcaatgtcat attgataacc actgtcttgt aagagtcgtt
    36241 tcaaataatc agctttgtct tgtgcttttg agtgaataat agacacatta tactgaccgt
    36301 ctgctatcaa gtcatttaaa atctcaacca agcgtttcat ggctttcttt tctgttctca
    36361 ctttttcata aacaacgatt tttccctctt catcaaagcg taaaataggt ttaatactca
    36421 aaagatttcc aagaagagca gacccatttg acaggcgtcc gcctttaacc agatgattaa
    36481 ggtcatcaac cataataaag gctgtcgtcc catcaatctg ttcttgcagc ttgtttaaaa
    36541 tagcttgaaa tgtcattcct tgacgtgacc aatctagcac attttttacc atactaccta
    36601 aaggagcaga tgtgatctta ctatctggaa atgccatttc aatctcagga tgttcttcag
    36661 ctaaaaattg aatattttgc caaaagcctg agattcctcc agctaagaac aagccaataa
    36721 catgtgtata acccttagaa gacaaaagtc ctaaaagatt atctagttca gataaacttg
    36781 gctgacttgt cttgggaaga ttttgggagt cagccatctt ttgataaaaa tcatctatac
    36841 tcaaatttcg accttcaaaa taggtctcat cgtcaatgat aactggtata tcaaggctaa
    36901 aaatagcttt atcttgtttc agatctgttg gtagtgttgc tgtactgtca gtaattactg
    36961 ctaatttcat taatttttaa actccaaatg aatacctgga cgatccaagg caatttctgt
    37021 gacttcataa gtcaatcgct taaccatgtc tagcaaagga gcagctaagg attcaacttc
    37081 ctcttgcgta aattcgcttg gtttatccac taaacgatct aaaatgcgaa ccatttgtga
    37141 gatgacccca ctaataacaa attcttcttt gacaataaca aattgcaata cagatacaat
    37201 tactgtttct ttttgctgct catctttatc aatcaactga aaagtcactt caaaattggt
    37261 ctctggtgtt ccgttttctt tttcccactc taaatttcta gcatcataat ggtactggtt
    37321 gacaaattct ttttcacgaa ctaattgcat tttttattct ccttggtatc aatatgatcc
    37381 attatagcat agatttgaag attattaaag tagcccctaa actactattt tcgcataacg
    37441 ttttaaacag tgctatctct cgaacagata tctatttttt cacctatttg tatttagtcg
    37501 tccttatact gacattatat caaaaaaaca cccgttagtg gtcttgtact gcacctcaat
    37561 taaaacagaa ccactggtca ggtaagtttt aagtccagga taaaaaggtt tatcaccaag
    37621 gcctcatcat gcttagccaa gtatttcgaa ctagcttgtc ttagctctaa tcgctcaaac
    37681 gtaaatccta ggcgttcaat ccgccgcaaa acctctccaa ctaacccata cttaaaccca
    37741 tagagcttaa tcatcgctcc gcccttcttc tccttttatc cattataaaa taaaaacgtt
    37801 ttaacagaca aaaaatagga aagtaccaga ctattggatt tattttttta tctcaaaatc
    37861 cattaacgat gttgagttaa aggcattcaa aacaacatag atcgtaagct aacaagattt
    37921 tttatcaatt gaacctatcg tccccagtta taccacgacc tcttctggat gaggtctttt
    37981 ttttatttgt ctaatttcat caacgcttct tcctctcttt cttctatcac agctctccta
    38041 ttgctcactt cctcatgcag caacatatca tcaaaaaacc gtccattttt aagcacaacc
    38101 actactgtgt ctcttgtgat atctccattg tcaatcgctt gtttacgttt attaaaaatt
    38161 attttaaaaa ttaaatatta ttttaaaaaa ttgcaacaat agatgtctat atgatataat
    38221 ctttttataa taaaattgta tagaaaaagg tactcttatg agaaaaagat gctattcaac
    38281 ttcagctgca gtattggcag cagtgacttt atttgctcta tcggtagatc gtggtgttat
    38341 agcagatagt ttttctgcta atcaagagat tagatattcg gaagtaacac cttatcatgt
    38401 tacttccgtt tggaccaaag gagttactcc tccagcaaaa ttcactcaag gcgaagatgt
    38461 ttttcgcgct ccttatgttg ctaaccaagg atggtatgat attaccaaaa cattcaatgg
    38521 aaaagacgat cttctttgcg gggctgccac agcagggaat atgcttcact ggtggttcga
    38581 tcaaaacaaa gaccaaatta aacgttattt ggaagagcat ccagaaaagc aaaaaataaa
    38641 cttcaatggc gaacagatgt ttgacgtaaa agaagctatc gacactaaaa accaccagct
    38701 agatagtaaa ttatttgaat attttaaaga aaaagctttc ccttatctat ctgctaaaca
    38761 cctaggagtt ttccctgatc atgtaattga tatgttcatt aacggctacc gccttagtct
    38821 aactaaccac ggtccaacgc cagtaaaaga aggtagtaaa gatccccgag gtggtatttt
    38881 tgacgccgta tttacaagag gtgatcaaag taagctattg acaagtcgtc atgattttaa
    38941 agaaaaaaat ctcaaagaaa tcagtgatct cattaagaaa gagttaaccg aaggcaaggc
    39001 tctaggccta tcacacacct acgctaacgt acgcatcaac catgttataa acctgtgggg
    39061 agctgacttt gattctaacg ggaaccttaa agctatttat gtaacagact ctgatagtaa
    39121 tgcatctatt ggtatgaaga aatactttgt tggtgttaat tccgctggaa aagtagctat
    39181 ttctgctaaa gaaataaaag aagataatat tggtgctcaa gtactagggt tatttacact
    39241 ttcaacaggg caagatagtt ggaatcagac caattaaagc gtatcaataa gaaaaattac
    39301 atttaataat aactataatt tagtatactg attaagttaa tgaattaaga tattaggaga
    39361 aaaaatggaa aaaaagtttt gacgttgttc attcttatgt gctcatcaat tattttatat
    39421 actactaagg gtatcttttc agatacgtat attacgaatg atattagaaa ttcagaagac
    39481 atctattttc ctagacagga taaagatggc attttagata ataaaagatt aaaagacatt
    39541 tatggtaaag aaattattga aaaaactaat ataccgataa atgccaaaca gggaacgcat
    39601 ttgattttta atacgaatga aaatactaca gtttgggatg ataatacttt tacaaaagtc
    39661 atatctagta atctttcacc ttcacaggaa agaatgttta atgttggtga tcatgtgaat
    39721 atttttgcta tcgtaaaatc atatcaggtt gtatgcaagg atcaattcaa ttatattgat
    39781 gggggaataa taaaaacaag tgatgtaaaa ccagaagaaa aagcaattta tattaatatt
    39841 attagtgaca aagaactacg agcattaaca gctaaagata agcttacctt caaaaataat
    39901 atggtaaccc ttcaagaaat tgatgttaga cttaggaaaa gtttgatggg agatagcaaa
    39961 ataaaattgt atgaatatgg ttctttgtat ataaaaggtt tttgggacat tcattataaa
    40021 gatggtacca ctagacacac caatttattt agctacccag attatacaga taatgaaata
    40081 attgacgttg gtaaagttag tcattttgat gtgtatttaa ataaagatat actttatgaa
    40141 taaataaaat attggcctag aataaaaatt gttttagcat tttatatata gtaattattc
    40201 cgttctttca cttaggttac atcttataat aacgagaaag aataaggaga ggaacaggtg
    40261 gtaatttgaa aagattaatc attaaaagta tactagtttt ttttctgatg tttatttata
    40321 catttaaaac agaaaagctc gttgagtcga aaaatagtaa tattgatgaa ataaaacatc
    40381 agttacgata tatatacaca attactcctt ctgattatag taattgcaat attagttatt
    40441 taactactca caattttagt gtggctacac ctggttatca atcaaaatgt ttttatgtag
    40501 attcagaagt agatggtggt gtcactgaaa aatttagaaa aggtcaaaaa gtcaatgtgt
    40561 ttggcctgcc ttatatattt tctccctata ataaaaatga tatttatggt ggaatcacac
    40621 cttcaacaga tgatggtatt ctaaggacta atactattgc agggaatttt ttcatagatg
    40681 gacaacagca aaaaacatta ataaatccta taaaaatcga taaggatatt gttacgattc
    40741 aagagttcga ttttaaaata agaaaatttt tgatggaatc aaaagaaatt tatttgacta
    40801 agtctcctta tataaggggg agtttagaaa ttcacagtaa aaataggaaa catgaaaaaa
    40861 tcaatttata tgacgcaaaa cccaatagca ccagatctga tgtctttaaa aaatataaag
    40921 acaataagac tataaacatg aaagatttca gccattttga tatttatctt tggactaaat
    40981 aaactaaaag ctttggataa atatgatcaa ttgacctata ataacattga taccaaatct
    41041 aaaactgctc agattgaatt gcgccccaaa agttagacaa aaaatctaat aattggggtg
    41101 tttttgtctg gcattaagtt tagctaataa ccttgcttaa atcacattaa accaataatg
    41161 gaaaaagaca tctcca
//
