LOCUS       NZ_CAAHKQ010000001     41176 bp    DNA     linear   CON 11-MAY-2024
DEFINITION  Streptococcus pyogenes strain A904, whole genome shotgun sequence.
ACCESSION   NZ_CAAHKQ010000001
VERSION     NZ_CAAHKQ010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (03-APR-2019) WTSI, Pathogen Informatics, Wellcome Trust
            Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900983695.1-RS_2024_05_11
            Annotation Date                   :: 05/11/2024 02:54:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,776
            CDSs (total)                      :: 1,717
            Genes (coding)                    :: 1,662
            CDSs (with protein)               :: 1,662
            Genes (RNA)                       :: 59
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 29 of 55
            Pseudo Genes (incomplete)         :: 29 of 55
            Pseudo Genes (internal stop)      :: 25 of 55
            Pseudo Genes (multiple problems)  :: 23 of 55
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:26:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 69608
            Orig. end                         :: 110784
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CAAHKQ010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..41176
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41176
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41176
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21176](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21176
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            complement(698..1348)
                     /locus_tag="E9664_RS00420"
                     /old_locus_tag="SAMEA3919112_00085"
     CDS             complement(698..1348)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /locus_tag="E9664_RS00420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00085"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_003061805.1"
                     /transl_table=11
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGRS
                     RQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYISE
                     VFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSSLAA
                     MITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            complement(1377..2240)
                     /locus_tag="E9664_RS00425"
                     /old_locus_tag="SAMEA3919112_00086"
     CDS             complement(1377..2240)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /locus_tag="E9664_RS00425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00086"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_041789020.1"
                     /transl_table=11
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWDTIKEKGVLKVATPG
                     TYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLNNF
                     DITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMKAAQ
                     KQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMSDVQY
                     NPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDKKIPVI
                     DTKDVN"
     gene            complement(2358..3812)
                     /locus_tag="E9664_RS00430"
                     /old_locus_tag="SAMEA3919112_00087"
     CDS             complement(2358..3812)
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /locus_tag="E9664_RS00430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00087"
                     /product="amidase"
                     /protein_id="WP_111684951.1"
                     /transl_table=11
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSER
                     FEAALEEAKQRDFSGLPFAGVPLFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVKRL
                     EALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGISALA
                     TASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTRNLLY
                     YLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALKQAVTWLR
                     EQGHQLVELEEFPVNMAEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMETMTWAIY
                     QSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVPDSKLMAN
                     LAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEGLPMGIQLI
                     AAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            complement(4009..4638)
                     /gene="pyrE"
                     /locus_tag="E9664_RS00435"
                     /old_locus_tag="SAMEA3919112_00088"
     CDS             complement(4009..4638)
                     /EC_number="2.4.2.10"
                     /GO_function="GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /locus_tag="E9664_RS00435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00088"
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="WP_002984920.1"
                     /transl_table=11
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSY
                     PKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDHGA
                     GNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNF
                     KEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            complement(4696..5388)
                     /gene="pyrF"
                     /locus_tag="E9664_RS00440"
                     /old_locus_tag="SAMEA3919112_00089"
     CDS             complement(4696..5388)
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /locus_tag="E9664_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00089"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_011184421.1"
                     /transl_table=11
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGP
                     DIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGL
                     GQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAI
                     KAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQ
                     AIKAEWAG"
     gene            complement(5665..6201)
                     /locus_tag="E9664_RS00445"
                     /old_locus_tag="SAMEA3919112_00091"
     CDS             complement(5665..6201)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /locus_tag="E9664_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00091"
                     /product="hypothetical protein"
                     /protein_id="WP_020905099.1"
                     /transl_table=11
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEFP
                     AHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLIDL
                     CQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEEEAF
                     IKYYQSPKIPTGEFE"
     gene            6423..7328
                     /locus_tag="E9664_RS00450"
                     /old_locus_tag="SAMEA3919112_00092"
     CDS             6423..7328
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /locus_tag="E9664_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00092"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_136047978.1"
                     /transl_table=11
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMGI
                     TIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFVVN
                     AFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDDNHL
                     TASPLFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMMSQMPH
                     NKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFIKHEKA
                     NLSKMGEHFIEYLLEEVTFD"
     gene            complement(7408..8196)
                     /locus_tag="E9664_RS00455"
                     /old_locus_tag="SAMEA3919112_00093"
     CDS             complement(7408..8196)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /locus_tag="E9664_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00093"
                     /product="hypothetical protein"
                     /protein_id="WP_002994010.1"
                     /transl_table=11
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERRE
                     LNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRSVS
                     PILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSRNVT
                     TKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSSQAFL
                     ENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(8189..8902)
                     /gene="deoD"
                     /locus_tag="E9664_RS00460"
                     /old_locus_tag="SAMEA3919112_00094"
     CDS             complement(8189..8902)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043096 - purine nucleobase salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="deoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /locus_tag="E9664_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00094"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_002990147.1"
                     /transl_table=11
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNM
                     FGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELV
                     LAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNM
                     PERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTF
                     TDMMKVGLETLIAND"
     misc_feature    9355..9368
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.2"
                     /tool="antismash"
     gene            complement(9568..10377)
                     /locus_tag="E9664_RS00465"
                     /old_locus_tag="SAMEA3919112_00095"
     CDS             complement(9568..10377)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /locus_tag="E9664_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00095"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_136047979.1"
                     /transl_table=11
                     /translation="MSLMTKINETKDFLVTKGIEAPEFGLILGSGLGELAEEVENPVVI
                     DYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKALG
                     CEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTKVYR
                     NKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVAAHSG
                     LKVLGISAITNFAAGFQSELNHEEVVEVTQHIKEDFKGLVKAILAEL"
     gene            complement(10361..10801)
                     /gene="arsC"
                     /locus_tag="E9664_RS00470"
                     /old_locus_tag="SAMEA3919112_00096"
     CDS             complement(10361..10801)
                     /EC_number="1.20.4.1"
                     /GO_function="GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /GO_process="GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /gene="arsC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /locus_tag="E9664_RS00470"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance.;
                     This arsenate reductase requires both glutathione and
                     glutaredoxin to convert arsenate to arsenite, after which
                     the efflux transporter formed by ArsA and ArsB can extrude
                     the arsenite from the cell, providing resistance; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00096"
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="WP_023079098.1"
                     /transl_table=11
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLI
                     ELLQSMGISARELLRTNVPEFEAHGLANQAVAEKDVINAMLTDPILINRPIVVTRKGVK
                     LCRPSETLLDILPVPLPSPYMKEDGESVNPIEVKGEKDVIDD"
     gene            complement(10820..12031)
                     /locus_tag="E9664_RS00475"
                     /old_locus_tag="SAMEA3919112_00097"
     CDS             complement(10820..12031)
                     /EC_number="5.4.2.7"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008973 - phosphopentomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /locus_tag="E9664_RS00475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00097"
                     /product="phosphopentomutase"
                     /protein_id="WP_020905095.1"
                     /transl_table=11
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISET
                     AGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGLNI
                     TEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTS
                     ADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRH
                     DYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTLIKTLQ
                     LPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLLLITADH
                     GNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTAMIGESFL
                     GHLK"
     gene            complement(12108..12791)
                     /gene="rpiA"
                     /locus_tag="E9664_RS00480"
                     /old_locus_tag="SAMEA3919112_00098"
     CDS             complement(12108..12791)
                     /EC_number="5.3.1.6"
                     /GO_function="GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /gene="rpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /locus_tag="E9664_RS00480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00098"
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="WP_136022278.1"
                     /transl_table=11
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEG
                     LQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLME
                     KIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDS
                     LLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLE
                     APKAG"
     misc_feature    complement(13026..13039)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.77"
                     /tool="antismash"
     gene            13170..15269
                     /locus_tag="E9664_RS00485"
                     /old_locus_tag="SAMEA3919112_00099"
     CDS             13170..15269
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /locus_tag="E9664_RS00485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00099"
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="WP_136047980.1"
                     /transl_table=11
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEE
                     FQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEIQD
                     TAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSLEAG
                     TQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSR
                     GELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMCIRNLYEQHHHIT
                     LSDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEIAKQKES
                     QEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMG
                     TNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGK
                     TELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRN
                     PYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFSQQDTE
                     TSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLT
                     IADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVI
                     RQNDQ"
     gene            complement(15327..16070)
                     /locus_tag="E9664_RS00490"
                     /old_locus_tag="SAMEA3919112_00100"
     CDS             complement(15327..16070)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /locus_tag="E9664_RS00490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00100"
                     /product="hypothetical protein"
                     /protein_id="WP_136047981.1"
                     /transl_table=11
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSSI
                     EGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQVER
                     DIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFEKLA
                     SQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAVGHTSFSKGLLTPNGYFDYTRF
                     GKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(16218..16817)
                     /gene="yihA"
                     /locus_tag="E9664_RS00495"
                     /old_locus_tag="SAMEA3919112_00101"
     CDS             complement(16218..16817)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yihA"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /locus_tag="E9664_RS00495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00101"
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="WP_002984945.1"
                     /transl_table=11
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSF
                     INTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMIEE
                     YLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHES
                     VVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            complement(16827..18056)
                     /gene="clpX"
                     /locus_tag="E9664_RS00500"
                     /old_locus_tag="SAMEA3919112_00102"
     CDS             complement(16827..18056)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /locus_tag="E9664_RS00500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00102"
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="WP_002984948.1"
                     /transl_table=11
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEI
                     IKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDD
                     DDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLK
                     LIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVP
                     PQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASY
                     MQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDG
                     VELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVE
                     GKSKPVLETA"
     gene            complement(18186..18356)
                     /locus_tag="E9664_RS00505"
                     /old_locus_tag="SAMEA3919112_00103"
     CDS             complement(18186..18356)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /locus_tag="E9664_RS00505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00103"
                     /product="hypothetical protein"
                     /protein_id="WP_002990165.1"
                     /transl_table=11
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLGSLFLLNAFTNLV
                     NSIHAFYGTLF"
     gene            complement(18376..18873)
                     /locus_tag="E9664_RS00510"
                     /old_locus_tag="SAMEA3919112_00104"
     CDS             complement(18376..18873)
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005542 - folic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /locus_tag="E9664_RS00510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00104"
                     /product="dihydrofolate reductase"
                     /protein_id="WP_136047982.1"
                     /transl_table=11
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKNTTLHQAILM
                     GRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGGNK
                     VLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVTALK
                     HK"
     gene            complement(18953..19792)
                     /locus_tag="E9664_RS00515"
                     /old_locus_tag="SAMEA3919112_00105"
     CDS             complement(18953..19792)
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /locus_tag="E9664_RS00515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00105"
                     /product="thymidylate synthase"
                     /protein_id="WP_011017679.1"
                     /transl_table=11
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFA
                     EYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRT
                     IGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVR
                     RVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYD
                     NQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI"
     misc_feature    complement(19748..19762)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.77"
                     /tool="antismash"
     gene            20001..21176
                     /locus_tag="E9664_RS00520"
                     /old_locus_tag="SAMEA3919112_00106"
     CDS             20001..21176
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /locus_tag="E9664_RS00520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00106"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_021299369.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 9.9e-08,
                     bitscore: 25.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSVA
                     PITEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFARS
                     FEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIALLVT
                     ANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQKRENL
                     QLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGNIYTGS
                     LYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQALLDQRT
                     RLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHQRIYHTNDKN"
     gene            21163..22440
                     /locus_tag="E9664_RS00525"
                     /old_locus_tag="SAMEA3919112_00107"
     CDS             21163..22440
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_process="GO:0016054 - organic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /locus_tag="E9664_RS00525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00107"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_002984963.1"
                     /transl_table=11
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLPI
                     QTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSGGF
                     KAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTIHLE
                     EKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESLVTTS
                     CEIPVRLLDRDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIATGNDWR
                     AIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPTVSIAHD
                     LLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGATQDEIAP
                     LVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(22670..23659)
                     /gene="fni"
                     /locus_tag="E9664_RS00530"
                     /old_locus_tag="SAMEA3919112_00108"
     CDS             complement(22670..23659)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /locus_tag="E9664_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00108"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_109991865.1"
                     /transl_table=11
                     /translation="MTNRKDDHIKYALKYQSPYSAFDDIELIHHSLPSYDLSDIDLSTH
                     FAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRL
                     HEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTWKKH
                     LAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRGGDRS
                     YLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVE
                     KYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(23652..24659)
                     /locus_tag="E9664_RS00535"
                     /old_locus_tag="SAMEA3919112_00109"
     CDS             complement(23652..24659)
                     /EC_number="2.7.4.2"
                     /GO_function="GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054377.1"
                     /locus_tag="E9664_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00109"
                     /product="phosphomevalonate kinase"
                     /protein_id="WP_021299363.1"
                     /transl_table=11
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAH
                     IQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKF
                     GIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVA
                     YTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQV
                     TASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVA
                     ACQKQDAVAKSSGSGGGDCGIALAFNQDARDTLISKWQEADIALLYQERWGEND"
     gene            complement(24652..25596)
                     /gene="mvaD"
                     /locus_tag="E9664_RS00540"
                     /old_locus_tag="SAMEA3919112_00110"
     CDS             complement(24652..25596)
                     /EC_number="4.1.1.33"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /locus_tag="E9664_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00110"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_002984972.1"
                     /transl_table=11
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFTT
                     TSISFLPDTATSDQFYINGVLQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAAGL
                     SSSSSGLSALVKACDQLFNTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAIYKV
                     ETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLKTNNF
                     EKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMDAGPNV
                     KVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            complement(25578..26456)
                     /gene="mvk"
                     /locus_tag="E9664_RS00545"
                     /old_locus_tag="SAMEA3919112_00111"
     CDS             complement(25578..26456)
                     /EC_number="2.7.1.36"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /locus_tag="E9664_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00111"
                     /product="mevalonate kinase"
                     /protein_id="WP_002984974.1"
                     /transl_table=11
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFPA
                     DKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRAVF
                     SYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIALNGY
                     LIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQLMTQA
                     HSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKISHRLKE
                     EGAVNTWIQML"
     gene            complement(26749..27981)
                     /locus_tag="E9664_RS00550"
                     /old_locus_tag="SAMEA3919112_00112"
     CDS             complement(26749..27981)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /locus_tag="E9664_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00112"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_010922165.1"
                     /transl_table=11
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRILH
                     LISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDREE
                     AQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLAVSV
                     MLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNELVEL
                     MTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAEDFKSLV
                     LKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIGRRRKRA
                     KLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFKGTITVNY
                     KNDAIVFTVVI"
     gene            complement(27990..28658)
                     /locus_tag="E9664_RS00555"
                     /old_locus_tag="SAMEA3919112_00113"
     CDS             complement(27990..28658)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /locus_tag="E9664_RS00555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00113"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002984985.1"
                     /transl_table=11
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAY
                     DIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFS
                     LKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLN
                     QGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
                     "
     gene            complement(28661..29311)
                     /locus_tag="E9664_RS00560"
                     /old_locus_tag="SAMEA3919112_00114"
     CDS             complement(28661..29311)
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /locus_tag="E9664_RS00560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00114"
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="WP_002984988.1"
                     /transl_table=11
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGF
                     KLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVDLL
                     KSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTIAQD
                     SWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     misc_feature    29447..29460
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     misc_feature    29526..29539
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     misc_feature    complement(29527..29540)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            29531..31543
                     /locus_tag="E9664_RS00565"
                     /old_locus_tag="SAMEA3919112_00115"
     CDS             29531..31543
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /locus_tag="E9664_RS00565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00115"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="WP_136047983.1"
                     /transl_table=11
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGALD
                     NTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANSAL
                     LQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEAS
                     HQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQNYEH
                     YQFLDVAETIAKYAKELQEQHVHAIVVLAHVPATSKDGVVDHEMATVMEKVNQIYPEHS
                     IDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFMTTPSANVVAVAP
                     GIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNLVTTAQLT
                     IAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQMTGQHIYDV
                     LNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNDEEINLTTTYTVVVND
                     FLYGGGDGFSAFKKAKLIGAINTDTEAFITYITNLEASGKTVNATIKGVKNYVTSNLES
                     STKVNSAGKHSIISKVFRNRDGNIVSSEVISDLLTSTENTNNSLGKKETTTNKNTISSS
                     TLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     misc_feature    complement(29542..29555)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.33"
                     /tool="antismash"
     gene            complement(31625..32035)
                     /locus_tag="E9664_RS00570"
                     /old_locus_tag="SAMEA3919112_00116"
     CDS             complement(31625..32035)
                     /EC_number="3.5.1.88"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /locus_tag="E9664_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00116"
                     /product="peptide deformylase"
                     /protein_id="WP_002984994.1"
                     /transl_table=11
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMA
                     ANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITVEY
                     LDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(32291..32509)
                     /locus_tag="E9664_RS09315"
     CDS             complement(32291..32509)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995561.1"
                     /locus_tag="E9664_RS09315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_014407501.1"
                     /transl_table=11
                     /translation="MALLFYYYVRKNQVKKLSQLKNLTEIFRKFIILTINNISAIKVFQ
                     TAGVLFGPVKVANARESSIWFENLTKQ"
     gene            <32752..>32829
                     /locus_tag="E9664_RS09185"
                     /pseudo=""
     CDS             32752..>32829
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /locus_tag="E9664_RS09185"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDYCNNKRIKIKRKGLSPLQHRTKSF"
     gene            complement(32927..34804)
                     /locus_tag="E9664_RS00580"
                     /old_locus_tag="SAMEA3919112_00117"
     CDS             complement(32927..34804)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /locus_tag="E9664_RS00580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00117"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_136047984.1"
                     /transl_table=11
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGINGTGKTTL
                     LDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSSDVKAIQLIRQYE
                     LLMADYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGMRRR
                     VQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHVATRI
                     FELDKAGLTEYQGNYQDYVRLKAEQDERDAANLHKKKQLYKQELAWMRTQPQARATKQQ
                     ARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQ
                     NKDRIGIVGDNGVGKSTLLNLINGDLEPTSGKLDIGDTIRVGYFSQQLKDMDETKRVIN
                     YLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLKLLIEKPNV
                     LLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFEEGDIRVFYG
                     NYSDYLDEKVFEKETVEADLVKTTVTEEVPLPQKEERKRMSYLEKQEWAQIEDKIATIE
                     ANIEEIENQMLTVVSDYDQLAQLQKELDQHNNDLLLAYERFEYLSGLDI"
     gene            complement(34801..36009)
                     /locus_tag="E9664_RS00585"
                     /old_locus_tag="SAMEA3919112_00118"
     CDS             complement(34801..36009)
                     /EC_number="2.7.7.72"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /locus_tag="E9664_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00118"
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="WP_168388732.1"
                     /transl_table=11
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIHD
                     VDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQVS
                     FVRSLEEDLKRRDFTVNALALDENGKVIDKFRGLIDLKQKRLRAVGKAEERFEEDALRI
                     MRGFRFAASLDFDIEATTFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGISAMIA
                     CQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTS
                     NDFQRYVTKLIALYRIRQERSFEKLDIYQYGKKMASLVEDLRKAQSLSVDMDHINTLDQ
                     ALVIHDKHDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREE
                     LAT"
     gene            complement(36134..36982)
                     /locus_tag="E9664_RS00590"
                     /old_locus_tag="SAMEA3919112_00119"
     CDS             complement(36134..36982)
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /locus_tag="E9664_RS00590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00119"
                     /product="DegV family protein"
                     /protein_id="WP_010922161.1"
                     /transl_table=11
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLSI
                     DDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLA
                     EEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIMVDD
                     LNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLI
                     ADGQYNVFIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPR
                     L"
     gene            complement(36982..37362)
                     /locus_tag="E9664_RS00595"
                     /old_locus_tag="SAMEA3919112_00120"
     CDS             complement(36982..37362)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /locus_tag="E9664_RS00595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00120"
                     /product="DUF1149 family protein"
                     /protein_id="WP_002985011.1"
                     /transl_table=11
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDEQ
                     QKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDMVK
                     RLTYEVTEIALDRPGIHLEFKN"
     gene            complement(<37564..37766)
                     /locus_tag="E9664_RS00600"
                     /old_locus_tag="SAMEA3919112_00121"
                     /pseudo=""
     CDS             complement(<37564..37766)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /locus_tag="E9664_RS00600"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="SAMEA3919112_00121"
                     /product="nucleoside-diphosphate kinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIKPDGFKYGLVGEVLRRIERLGFTFERLELRQASSKYLAKHDEA
                     LVINLFILDLKLT"
     gene            38268..39293
                     /locus_tag="E9664_RS00605"
                     /old_locus_tag="SAMEA3919112_00122"
     CDS             38268..39293
                     /EC_number="3.4.22.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635407.1"
                     /locus_tag="E9664_RS00605"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases.; This family includes IgM or IgG-cleaving
                     cysteine proteases.; This family includes IgM or
                     IgG-cleaving cysteine proteases; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="SAMEA3919112_00122"
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="WP_136047985.1"
                     /transl_table=11
                     /translation="MRKRCYSTSAVVLAAVTLFALSVDRGVIADSFSANQEIRYSEVTP
                     YHVTSVWTKGVTPPAKFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNMLH
                     WWFDQNKEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKAFPG
                     LSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGDQSKL
                     LTSRHDFKEKTLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSNGNLEA
                     IYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQDSWNQT
                     N"
     gene            39412..39678
                     /locus_tag="E9664_RS00610"
     CDS             39412..39678
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014875.4"
                     /locus_tag="E9664_RS00610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="WP_281726943.1"
                     /transl_table=11
                     /translation="MDKDIVTIQEFDFKIRKFLMESKEIHLTKSPYIRGSLEIHSKNRK
                     HEKINLYDAKPNSTRSDVLKKYKGNKTINMKDFSHFDIYLWTK"
     gene            <39876..40193
                     /locus_tag="E9664_RS00615"
                     /pseudo=""
     CDS             <39876..40193
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /locus_tag="E9664_RS00615"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="KCYDGTI"
     gene            complement(40250..40957)
                     /locus_tag="E9664_RS00620"
                     /old_locus_tag="SAMEA3919112_00124"
     CDS             complement(40250..40957)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /locus_tag="E9664_RS00620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMEA3919112_00124"
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="WP_002990206.1"
                     /transl_table=11
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSST
                     RHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNGSS
                     VTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQDATA
                     ALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAET
                     LAVDEAWAKRMTY"
ORIGIN
        1 aagatgacaa agggcttgga tgagggctct cgatgatgtg gtgctttgga ttagtaatga
       61 aggctttttt cttccttgca taagctcccc acaaaatgaa aactacaggg atgtctttct
      121 cattcagcac tttaataaca gcgtctgtaa atggctccca tattaagcct gcatgcccat
      181 tagcctggcc tgctggcact gttaagcaag cattcaaaag cagaacccct tgactagccc
      241 aagtgcttaa atcatgatgg tcacgaggac caatgtcatc tgctaattct tttaaaatat
      301 taataaggga tggcggagca gaaatctctt ctggaactga aaatgataag ccctgggcct
      361 gtttggggcc atgataaggg tcttgtccta aaatcaacac tttggtttct tccaaaggag
      421 tgacttgtaa ggctttaaag acattttctc gtggaggata gacaagaccg gaagcatagg
      481 cttcatctaa aaagtgattg atgcgaccgt agtaatgctc cggcaaaaat gatttgattt
      541 tctcatgcca aattgaatga gccataagat tcctttctaa tcacgtcagt ttctaagtta
      601 aatacgatgt ccttttctat ctagtttacc acattttaaa tagaaagacc ctgaaaatat
      661 gatatttcca gggttaatat tcgtttttta caggatatta aacaagtgct agcttatttt
      721 ctaagaattc ttggtaacgt tctaacaaaa aagcaataag ccaatagata aaggctacta
      781 aaatatacat ggacatgtaa tcccactctc taccgccaat aattttggca ttttgaaaaa
      841 tatctggtac ggtaatcatg gcagctagcg acgaactttt aaccatatca ataatgacat
      901 tgcctagagg aggaactgca attcgaaaag cttgaggaag aataattttc ttaaccataa
      961 gagcatatgg caaccctaaa gccttagctg cttcccactg tcccttgtca atagcttcta
     1021 tagaggagcg aaaaacttca gaaatatagg cagcgctaac catagaaaaa ccaagataag
     1081 cgcaaagtaa agctggcaat tctaaaccat aataaggcaa cccgaaataa agaacaaaga
     1141 gcaccacgat catcggcaca cctcgcataa tagagatgta cgctctaaca agataatgaa
     1201 tcaacggctg acgtgacctt cccagaaggg ctaggcctaa acctaaaaac agacccgtaa
     1261 aaaaactgag caacgaaata ccaagggtat aaggtaatcc cgataacaca aatcctaaac
     1321 tatctttcat taatgggata ttaatcatgt ggttaggact cctttaacat caagtattag
     1381 ttaacgtctt tcgtatcaat gacgggaatt tttttgtctt tgccaaaagg ttttgtcaga
     1441 tcttgaccag catagtaggt ttcagagatt ttcttcaagc taccatcttt tatcatgtct
     1501 ttaataacag catctatttt tttcttgagg ctatcgtctt ttttgttcat aacaattcct
     1561 tgttcggttg ggttgtactg aacatcgctc attttgacat ttagatttgg attttgagat
     1621 aacatgtaat ccacaaataa tttttgagct gggtaatcat ttgggatgaa atctgttcga
     1681 ccgttagcca catcgtttag ataaacatct cctgtaacat tatcgtaggt caccagttcg
     1741 gctccctgtt tttgcgctgc tttcatgtac tctgttccag aagcgccggc tgcttttttt
     1801 cctttccagt cgctaagatc ttttttagcc atgtttgagc tgccatcagc acggacaatc
     1861 atgcctccta ccccgtattt ataaggcgta gagatattgt attttttctg acgttttggg
     1921 gtaatgtcaa agttgttcaa agaaatatcc actcgaccac tatcaactga ggtaaaggct
     1981 tggtcaaatc ctgtttcaac aaacttgact ttaatgttaa gtcgtttacc gatttctttg
     2041 accatatcta cttcgtaacc tactaactca ttattatcgt tgtaaaaaga agttggctga
     2101 taggttcctg gggtagctac ttttaacacc cctttttctt tgatagtgtc ccaacttgat
     2161 ttttgagatt tatgtggcgc acatgctgcc aataaaaggc tggcaagtcc gatagacagt
     2221 aatgtaactg atttcttcat agtaactcct ttattaagat aagaatagta taacattttg
     2281 attaagttgt gttatcagtg agcgctcaat ctctttaaaa agttaatcta taatagttaa
     2341 actgttttat aagattatta ttgaggaatc ttcaataatc ctgctgcctc aaactgctct
     2401 gcaattccta ataataggtc ctctctacct ttggctgcaa ttagttgaat gcccattggg
     2461 agcccttcct tagtttcgta agtaggtaaa ctaatagctg gctggccagt tagattaggc
     2521 agagctgtgt aaggattaat agccagactc ttaccaaaca tggtttcgac caaattgaat
     2581 tgctcttcac tgctgaaaat ttcagcttga gccaagttag ccatgagttt cgaatctggg
     2641 acaagttctc cgtgcttagg agctggtgtg ttggttgtga acgtcaacaa caggtcataa
     2701 gtctcatgaa aactagccat ggttgcactg tacgtatccc atttttgaag gacctgtgag
     2761 taacgccaag ctgggatgtc tttacctgat tggtaaatag cccaggtcat ggtttccata
     2821 tcgtctttgg tcatcggacg tccaaaagtg tcttcaatat cagcaaacat agcagccgtt
     2881 tccacactat tcataatata ataatgacga atcacttctg ccatatttac aggaaactct
     2941 tccaattcaa ctagctgatg cccttgttct cttagccaag ttactgcttg ttttaaagct
     3001 tttgcagtat ctaaagatac tggactaccg tcacttaacc gttgataaaa agcaattgtc
     3061 aagggacgtt gtagcgattg ataaatgcta tcttttgtta aggtggctag ggggaagggg
     3121 ctttccattt gttccatctg taaatagtag agtagatttc tagtatctct aacggatttg
     3181 gtcaaggcaa aatgaactga ggctccttgc cagcttcgat aagaaccagg tccgacaggc
     3241 atgcgcccac ggctaggttt gagcccaatt aagccattaa acgaggctgg aattcgaata
     3301 gaaccaccac catcactagc agttgctagc gcactaattc ctgatgacac tagagcagca
     3361 gctcccccag atgagccacc agcatttcgt gtattatcct ttggtaaatt cactggtccg
     3421 tgcaaactgc tatcgctaat atttttaaag ccaaattcag gcgtgttgga gcgccctaaa
     3481 ataataaagc ctaaagcttc taatcttttc acaaataaat ccgttttagt tgcttgatac
     3541 tctttaaaca atctggaacc tgaggttgat gagtgacctt ttaattcttg tcccaaatct
     3601 tttaaaaaaa gaggcacacc agcaaaaggc agacctgaaa aatccctttg tttggcttct
     3661 tctagggctg cttcaaagcg ttctgaggta atagcattta aggtagggtt caacttttta
     3721 gccttataaa tagcctgggt tactaattct agtggtgtgg tctgaccagt ctgaacagca
     3781 atagccatag ccgtcgcatc ttgataagtc atagctactc ttcctttcta agatatgaat
     3841 cctaaaacat tcttttttat taaaacacaa ataaaagaaa accaccatta aaaggttaga
     3901 aattagaatg tgatgtgtaa ggaatgtaga caaaacaatc aaaacataac atttggaatt
     3961 ggggctaaag agattttttc attaaaaata aacctggctg atagttcctt attgttgcca
     4021 gtttacctgg tcttctttaa attttttaag taaatgtaaa ccatcattag taatatagcc
     4081 ttgcaacttt gcaactgcaa ttagctcagt ataattagaa agcgtaatca acttgatacc
     4141 agcttcttta aaattctgac tagcttttgg taactcataa gtgaaaatcg caacaactcc
     4201 cagaacgtca gctccctcac gactggctgc tgcggctgca tctagtaccg aaccacctgt
     4261 tgaaatcaaa tcttcaatga taaccatttt ttggccttta agcacacgcc cctcaatctg
     4321 gttgcctgct ccatgatctt ttggcttact gcgaatataa gcaaaaggaa gagtcatttt
     4381 atctgctata atggcaccgt gaggaatacc tgctgtagct gtaccagcga tgacctcaac
     4441 ttctgggaaa tgagccctga tagtttccac aaacccattc tcaattaaat cacgagtctt
     4501 aggataagaa agggtgacac gattatcagt gtaaataggt gatttaatgc cagatgccca
     4561 cgtaaaaggg tcttcaggct ttaaataaac agctttaata tcaagtaatt gagttgcaat
     4621 ttggcttgct agtgtcattt cttattctcc tttttcttct ttaacagaca agtgttggtt
     4681 tcctaatctt atctgttagc ctgcccactc agcttttatg gcttggtaag cagccactgg
     4741 gtcttttgcc tgggtaattg gtcgccctac cacaatataa tcacttccaa tgcgtcttgc
     4801 ttggtttgga gtcatcactc gtttttgatc gccaatatta ctgcctttag gacgaatgcc
     4861 aggagttaag caagtaaatc ccgtaggcgt caccgccttg atagcttcta cttcttgtgc
     4921 cgaacaaacc accccatcta gctgagcttt agctgccccc ttgctgtaat gcaaaacaga
     4981 ctctaaaaga ctcgtttgaa tattttgatc accacgcatt tggtcttcac tggttgaagt
     5041 tagctgcgtt accgcaatta aggtagggcc ttggcctagt ccttctcgag ctgcttttag
     5101 catctctaca ccaccagctg catgaacagt tgccatatca atatctaatt ctttaagaac
     5161 tgccatagca gcacgaacag tatttggaat atcatgtaat tttaaatcca aaaatacatt
     5221 atgccctaac gatttgatat accgaacaat atctggtcct tgcgcataat ataattccat
     5281 accaattttc acgtatagct tttcttctgc tggaaataag tctaaaaatg ctttagtctc
     5341 ctcaaatgat gaaaagtcta aagcaataat tgggcgttct tctttcataa cttatccttt
     5401 ctataatgtg tcaatatctc attaagcacc aaaaagcctc gctaccaaag aagcgaggct
     5461 acagcaaact aaaagggaat tccctttttt tatcttgtat accttgtttg cctctctgga
     5521 ctcacttaaa ggtgtctaaa tttaaactat tatagctttt ttaaaacaag atgtcaaaac
     5581 tttttgttat ttgaacacat ttttcctact atatcttttt ttgtatactt acgtcaactc
     5641 attttatcat ttttacccaa tcatttattc aaactcacct gtgggtatct tagggctttg
     5701 gtaatatttt ataaaagctt cttcttcaag attaaccctc tggatatgtt catagagcac
     5761 atccggaata ggagcttcct taagtgacaa agcactcact tttaaagatg aaaaaacatc
     5821 acttaagacc ccaaaaactc gaatgcgttt atctccaata ataatttgaa agacttcttt
     5881 ggactggcat aaatctatca gatgatccac tcctttaatc caattatcga caatatccaa
     5941 agttttgttc atcaacttaa aagctgattc ttcataccaa aaggtagact caatcaagcg
     6001 ttgctgcata tccaaggtat caatggccgc aacaatatct cccaactcag actgtactaa
     6061 atgagctgga aattcccctc caagtataga aggagttcgt tctacaagct tcagttcatc
     6121 tcgaaaaaga gtcaaatagt ggatactgac caataacttt tggattaaga tttgatgact
     6181 attttgttca gtaacattca cacgaccacc accctttgat tagaaaaata cctatttgtt
     6241 aatactatta atataacaca agaaaaataa aagggcaatg aaattgatag attcaactct
     6301 caaaattgaa tcatatttat cctaggccat attgagaaaa gactccagcg ctttttcaaa
     6361 gttctaaacc catgatgacg tttgtgcttg cgtctttatt ttttttgagc tagactgtac
     6421 ttatgagaat tcaacaactg cattatatta tcaaaattgt tgagtgcggc tctatgaatg
     6481 aagctgctaa gcaattattt atcacacaac caagtctatc caatgcggtc aaggatttgg
     6541 aaatggagat gggcattacc attttcaacc gaaatcctaa agggatcacc ttgacaaaag
     6601 atggggtgga atttttatct tatgctcgcc aaattataga gcaaacatca ctgttagaag
     6661 accgctataa aaaccacaat actggccgag agctctttag cgtttcatct caacattatg
     6721 ccttcgtagt caatgcattt gtctcactcc tcaagcggac cgacatgact cggtatgaac
     6781 tctttttgcg cgagacaaga acttgggaaa tcattgatga tgtcaaaaac tttcgatctg
     6841 aaattggtgt tctctttatc aacgactata accgagatgt cttgaccaaa ttatttgatg
     6901 acaatcattt gaccgcctct ccattattta aggcacagcc tcatattttt gtcagcaaat
     6961 caaatcctct agcaactaaa agcctattaa gcatggacga cttgagagat tttccttacc
     7021 tgagctatga ccaagggatt cacaactcct tttatttttc agaagagatg atgtcccaga
     7081 tgccccacaa caaatcaatt gtggtcagtg accgtgccac cctctttaac ttaatgattg
     7141 gtttagatgg ctacaccgtt gccagtggta ttctaaatag caatctaaat ggtgaccaga
     7201 ttgtggctat cccgctagat gtccctgacg aaattgacat tgtttttatc aagcatgaaa
     7261 aagccaactt gtccaaaatg ggggaacatt ttatcgaata ccttctcgaa gaagtaacct
     7321 ttgattaatg tctttttcaa tcgtcatact aaaaaaacac ggtagtaaga cctgtatcgg
     7381 tcaagttatc gtgttttttg ataaatatca gacaatagat tgtctccaaa ggctcaactc
     7441 ctttttaata atggcattca tgtcatcaaa gtaaaaaggc tcacgtcggt agattacacc
     7501 agaaaaagtc gccaaggtga taatgttttc caaaaaagcc tgagaagaaa aatgagtggt
     7561 gcgatgcagt tcctcttcat caaaaggctt aatcaaatga gccagaggat tacggacagc
     7621 cttttcaaaa tgtcgtaaca aaaaaaccaa gtccttgatt tcttgaggta aggaggtcaa
     7681 cgtcaacatg tctgctaagc ttttggtcgt cacattgcga gactgctttt gagacaggta
     7741 agccttaaaa acctcgtgat cagattccaa catggcctga aaatgccagg tatcatattg
     7801 gtcattcttt gtatcaaaaa tataagcctt gaagtttgga atttctgacg tgattagtct
     7861 gagaaaaagt cggtaaagaa taggcgacac tgacctgaca aaatcaataa tagcaccgtt
     7921 ttttacttta acttctaaat ccaaaatgta attggcaatc tgctcatctt caagcgattg
     7981 gttaagccat aatgaacagt ggtactggtc ttcaatggtc cgattctctg ctgcatgttc
     8041 cgccagaaag gcaaggttca attctctgcg ctcttttaac atctctagta aatagagagc
     8101 agttttaggg atatttggca aggctttagc aattctaaag gcgtgattat aagcatagac
     8161 atccaaaagg atgtctagcg tttgattatt agtcattggc aattaaagtt tccaagccga
     8221 ccttcatcat atcagtgaaa gttgtttggc gctcttcagc tgtagtatct tcggttggat
     8281 cattcaagtt atctgagatc gtcatgattc caagggcttt gacatggtgc tgagcagcta
     8341 aatagtaaag agctgctgct tccatttcga tggctttaac acccaattta ccaagagcca
     8401 tattacgctc aggcatgtta gtgtaaaaga catcagaaga aagcacattc ccaacgtgag
     8461 ttgttactcc catttctctg gcgatatggt aagccttgtc aagtaaacca aaatcagcaa
     8521 tttgtgggaa atcaaattct gggaagtcat tacggataat gtttgagttg gttgctgctg
     8581 cttgggcaag caccaattca cgcacatgaa cttctgggtc aatcgcaccc gcagtaccaa
     8641 cacggatcaa tgttttgaca ccgtaatcaa cgattaattc acgagcatag atagagatcg
     8701 aaggcatccc cataccagtt cccatgacag aaacgcggtg ccctttgtaa gttcctgtgt
     8761 agccaaacat gttacgcact tcgttaaaac acactgcatc ttctaggaaa ttttcagcga
     8821 taaatttcgc gcgcaaaggg tctccaggta gaagaatttt atcagcaata tcaccttttt
     8881 tggcagaaat atggatagac ataaattatg atactgaggg cgttaaaaga acgatggcaa
     8941 aataggaagt tggcagaaaa tcctgatttt ctagacaact tatctttttg accaagtcct
     9001 tagcccgaat tcaaattaat gaactcagcc ctcacctttc ttattttttt attttttata
     9061 aggaagaaaa acagttctcc gcccgtattc aattcaatga atacagttag ccctaccttt
     9121 ccttttattt tgtagaaggt cagagggcgg acagaaagca actgaaattt agggaactaa
     9181 cgccatgtgt gagcacaaaa gttagtttat ctagtttccg agctttccgc ccgtattcaa
     9241 ttgaatacaa ccccattcct ttcataattg atattgaata gaagaagaga gctaaaaatc
     9301 gagttcaaat aataaaggac taactctctt tcctttatta tttaaaaatt aatacgaaga
     9361 aatgttcgag tccatgctta atttaaaccg aatacgtctc tttcccttcg ttggttatgt
     9421 tagttagaaa agctagaatc tgagttcaac attcatagaa ctcacacccc gtgattattt
     9481 tttgattttt ttattgcgaa cagatgtgcc aaactgacga cataaaataa cattcctgta
     9541 ataatgctcc agttgatttt gttcgtccta caactccgct aaaatagctt taacaagacc
     9601 tttgaaatct tctttgatat gttgggtcac ttccacaact tcttcatggt tcaattctga
     9661 ttggaaacca gctgcaaagt tagtgatggc tgaaatgcca agtactttaa gtccagaatg
     9721 agcagccaca ataacttctg gcacagttga catgccgaca gcatctgctc ctaatacttt
     9781 gaaagcacgg atttctgctg gtgtctcata agttggacca gtcaagccca tataaacacc
     9841 atcttctagt ttgatgttca ttttttcagc cacttcatgt gccttattgc gataaacctt
     9901 agtataggca tcagacatat caggaaagcg tggaccaaac tcgtccaagt tttcaccgat
     9961 tagtgggtta tttccggtca tattgatatg gtctgtgatt gccatcaagg tacctgggcc
    10021 gtagccgata ccaccagctg catttgtgac aagaacgcct tcacatccca gagctttcat
    10081 gacacgaaca gggaaagtca ccacttcaag cgggtttcct tcgtaaaaat ggaaacgacc
    10141 ttgtagggca agtactttac gaccagctaa atcaccgtag actaattttc cagcatggcc
    10201 aacaactgtt gatttgcccc agtttggaat atctgcataa tcaataacaa caggattctc
    10261 tacttcttca gcaagttcac caagtcctga acccagaatt aatccaaatt cgggagcttc
    10321 aattccttta gtaactaaaa agtcttttgt ttcgttaatt ttagtcatca atgacatctt
    10381 tttctccttt tacctcaata gggttcacac tctcgccatc ctctttcata taaggactag
    10441 gcaggggaac aggaagaata tccagtaagg tctcagaagg acggcaaagt tttactcctt
    10501 tgcgagtcac aacaatagga cgattgatca aaattggatc cgtcaacatg gcattaataa
    10561 cgtctttctc agctactgct tgatttgcta atccatgagc ctcaaattca ggaacattgg
    10621 ttcgcaagag ttctcgcgca gagattccca tcgattgtaa gagctcaatt aaagtctccc
    10681 gattaggtgg cgtctgcaaa tactcaataa tagtaggctc aatacctgca tggcgaatca
    10741 tggcaagaac attacgtgaa gtgccacagt ttggattatg ataaatcgtg atttcttcca
    10801 ttatcaatta ctaactttct tattttaagt gaccaaggaa tgactcccca atcatggctg
    10861 tatcaactcc aaaattttct gcaacagtcg ctgaaatatc tgcaaaatgc ccttgtggaa
    10921 taagaccatt tccagtaaag gatgcagagt aggcaagcaa tggaatgtat tcacgagtgt
    10981 ggtcggtgcc tgcataggtt gggtcattac catggtcagc agtgatgaga agcaaatcgt
    11041 cttctttcat atttgcgatg atttcaggta ggcgattgtc aaattcatgc aagcagtcgc
    11101 gataaccctc tgggtcacga cgatgaccaa agttggcatc aaaatcaacg aggttagtaa
    11161 aggagaatcc cttagtaaac tcaggtaatt gaagagtctt aataagcgtg tcaataccat
    11221 ggctgttcga cttattgtgt cccatgtcgt ttgtaatacc tgaaccatta aagatgtcat
    11281 taatcttacc aacggcataa gttgggacac ctgcgtcagc cagtttgttc aaaacggtat
    11341 cttggaaagg agacactgca tagtcatgac ggttagccgt acgtgtaaag tttcctggtt
    11401 cgcctacata aggacgcgca ataatacgac ctaaaagggc agggcgttca agcgtgatgg
    11461 agcgagcata ttcacaaatc ttgtaaagct cttccacagg aataatgtct tcatgggctg
    11521 caatttgaag cactgggtct gctgaggtgt aaacaatcaa ctcacctgtt tccatttgac
    11581 gcggaccaaa atcatcaata accgcagttc ctgaataggg tttattagct tcacgaataa
    11641 ttttgcgacc tgagaattct tcaatcttag ttaaaatctc ttctgggaaa ccattccaga
    11701 aagtgtcaaa aggttctgta atgttcaagc ccataatttc ccaatggcct gtcatggtat
    11761 cttttccaag agatacttct tccaatttgg tcacgtaacc agtaggatta tcttctgttg
    11821 gaacagtttt tagtggtatt ggacgagaaa tgtttccaag tccaattttt gccatatttg
    11881 gaaccgataa gcctgctgtt tctgaaatat gaccgagggt gtcagaatct gtatcagcta
    11941 caccagcatt aaagaatttg tcagcatctg gtgctgcacc aataccgaca gagtctaaaa
    12001 caaccaagtg aatacgatta aattttgaca taagtctcca atctagggga ggttacggtt
    12061 gactccccaa tacctataaa atatattaac actgttatat gctaagacta gcctgcttta
    12121 ggcgcttcta aaacagtaac accgtcttta ctagcaacaa tcaccttatc aaccatacca
    12181 ttaaagagac cgtgttccac aacaccaact gttccatcta acaggtgacc aaaagcaaca
    12241 ggatctttaa tacaacccaa atcaagatca ataatatagt tttgcatgtc tgtcaccaaa
    12301 agactatcac ctttcatacg aaaagacggt ttgtaaccag ctttttcaaa gacacggaac
    12361 aaacgatcag caccatattg aacgacttcg actggtaact taaaggcacc cagatgctct
    12421 accattttag aagcatcaac aacccagatg tattcttttg ttggtgttgc aacaattttt
    12481 tccattagta aggctgcgcc gccacccttg attccattga aatccttatc cacttcatca
    12541 gcaccatcta cggtgaggtc aatgctatca atatcatcta tcgattttaa aggaatgcct
    12601 aagccttctg cttgcttgct agtcacactt gacgtggtca caccaaccac ttgcagtcct
    12661 tcttgcttta cgcgacggcc aatttcctca acaaaatagt aagccgttga cccagttcca
    12721 agcccaatgg tcatgccatc agtcacatat tgcgcagcgg taacaccggc aatttttttg
    12781 agtgcttcca tgattccccc ttataataga attgcgtctt agcactttat tataccatga
    12841 aagcgccaac ttgttaatga aaacatttgt ttttctctca ttgacagtct aagtgctata
    12901 gaataggatg atctttttaa aacttatgat ttattctaaa gtcatcatat aagcacttac
    12961 ttttcgtgtt tatttagctt tttgaaaatc aagtgttttt tgtttgacct ttactgacct
    13021 tttgattata ataatactat aagatgagta aaaataatgt ctgaatcatt ttattagcaa
    13081 aggatttcct atcatgtgaa atcctaacaa cgattctgcg actgcttaca aacatcttat
    13141 agtctatttt ttattgcgag gtaactgata tgacacattt ttctggtaaa gatccttttg
    13201 taaatatgga tgatattttc aaccaattaa tggcaaacat gggtggttat cgtagcgaaa
    13261 atccccgcta tctcgttaac ggtcgcgaaa taactcccga agaattccaa cactatcgtc
    13321 aaacaggaca actccctgta gcaacaacca aagcaacaaa ttctcaaatg ttaacaccta
    13381 aagctgatag tgtattgact caactcggaa ctaacttaac acaagaagct cgtcaagggc
    13441 atcttgaccc cgtcattggt cgtaacaaag aaattcaaga taccgctgaa atcttggcac
    13501 gacgaactaa aaataatcct gtccttgtcg gagatgctgg tgtcggtaaa actgcagtca
    13561 ttgaaggttt agctcaagcc attgttaatg gagatgtccc agccgctatt aaaaacaagg
    13621 aaatcgtatc aatcgacatt tctagtcttg aagctggtac acagtatcgt ggttcctttg
    13681 aagagaccat tcaaaacttg attcaagaag taaaagaagc tgggaatatc atcttatttt
    13741 ttgatgaaat tcatcaaata gttggtgctg gtgccacaag cagtgattca ggctcaaagg
    13801 gacttgcaga tattcttaaa ccagccttgt cacgaggaga attaacactg attggtgcta
    13861 ctactcaaga cgaataccgc aatactattt taaaaaatgc tgctcttgct cgtcgcttta
    13921 atgaagttaa agtgaatgca ccatcagctg aagatacttt tcacatttta atgtgtattc
    13981 gtaatcttta tgaacaacac caccatatta ccctttctga taatgttcta aaagctgctg
    14041 ttgattattc tattcaatac atcccacagc gtagcctgcc agataaagca attgacttac
    14101 tggatatgac agctgctcat ttagctgcgc aacacccggt cactgactta aaaacactcg
    14161 aaactgaaat agctaaacaa aaagagagtc aagaaaaagc tgtcgccaaa gaagactttg
    14221 aaaaagcttt agcagcaaaa acacggattg aaacattaca aaagcaaatt gagcaacata
    14281 accaaagcca aaatgtcact gctacagtca atgatatcgc agagtctgta gagcgcttaa
    14341 ctggtattcc tgtctctaac atggggacta atgatttaga aaggctcaaa ggaattagca
    14401 gccgcttaaa aagccatgtc atcggacaag atgaggctgt tgcagcagta gcacgtgcta
    14461 ttcgacgaaa tcgagcaggt tttgatgatg gtaaccgtcc aataggttct ttcctttttg
    14521 tgggtccaac tggtgttggt aaaacagagt tagctaaaca attagcactt gatttatttg
    14581 gttccaaaga tgctattatt cgacttgata tgtccgaata taacgatcgc actgctgtgt
    14641 caaaattgat tgggacaacg gctggttatg ttggctacga tgataataat aataccctaa
    14701 ctgagcgtgt tcgtcgtaac ccttatgcta ttgtcttact agatgaaatt gaaaaagctg
    14761 atcctcaaat cattacactt cttctacaag tgttagatga tggacgattg acagatggac
    14821 aaggaaatac tattaacttt aaaaataccg tcattattgc tacatcaaat gccggtttta
    14881 gccaacaaga tacggaaact tctgagtcta acattatgga tcgcattgca ccttatttca
    14941 gaccagagtt tttgaaccgt tttaatagta tcattaaatt taatcatctg caaaaagaaa
    15001 atttagaaga aattgttgat ttaatgctag ctgaagtaaa tcaaaccacc gcaaaaaaag
    15061 gtattagttt aacgattgct gatgacgcta aagctcattt gatagattta gggtacaatc
    15121 acgctatggg agctcgtcca ttacgacgta ttatcgaaca ggaaattcgt gaccgtataa
    15181 ctgattatta tcttgaccat ccagaagtca aaaaacttca ggcaatccta aaagaaggac
    15241 aactagtgat taggcaaaac gatcagtaat aaacttcttc aattgaataa ttttcaaaac
    15301 atgaaaaaat ccgtcttgtg actacgttat acacttgacg gacttttttt tagcgctttt
    15361 ttaaaaataa ttttttcatc gcctaataac tcaagtttct ttccaaatct ggtgtaatca
    15421 aaataaccat taggtgtgag caatcctttt gaaaaagaag tatgtcccac tgctacttct
    15481 tctttgatat caatggtgtg caaaatacga ttaacttttc ctttgagaac aacagcagat
    15541 aaatgtcctg ttttttgatt atatttgcct ccgatctgag aagctaattt ctcaaaagct
    15601 tgatctaaaa tcatttctaa ttcatggcta gctggcatac tattctcaat aatttggcgt
    15661 tctttactac tcaagtcacc aacaactaaa tgattttcct ttaatgtctt taataattca
    15721 ttttggtgat aagcagctaa acgtttgaca aaaatgtctc gttcaacttg aacactaaaa
    15781 ctcaagtcaa cgttgttatt tttaactgtt agtatcatct gagatgacgt taataaacta
    15841 tcatcaataa gagggctctg atgcaaacca gtaagacgtt tagcaaaatc atcgcctaac
    15901 ttctgatcaa tgcttgttgt tcgccagata ccttcaatag agctattacg atatcgaaca
    15961 ccaaaaagta cagcaagcaa gataagaaaa ataataaata caaaaagggc attgcattga
    16021 tggcataaca atgactttcc tttagagcgc ccttgggcta cttgtgtcat gactcatctc
    16081 cttaatataa aatactagca tgtcatcatt aaggcgtcaa gtaaaatcgg taaacctaac
    16141 tatgattttt tatgttttcg ataagaaaaa caccctctac tgagaatgtt ttagcataga
    16201 taaatcaaca cctatcgcta gacctgctct aaaatagcat cccaagaatc atcgatacca
    16261 atacgttcta ccgaagaaaa tactataaaa gtatcagatt tgtcaaaatt caaagctttc
    16321 ttgaccacag actcatgttt gttccatttg ccacgaggaa tcttatctgc tttggttgcc
    16381 acaacaataa caggaatgtc atagtacttc aaaaagtcat acatctgaat atcttctttt
    16441 gaaggggcat gacgtaaatc aaccaaactc acgactgcac gcagattgtc tctgctggtt
    16501 aagtattctt cgatcatctt tccccatttg gcccgttcac ttttagaaac cttggcatag
    16561 ccataaccag ggacatccac aaatctaagc ttgtcatcaa tattgaaaaa atttaatagt
    16621 tgggtttttc ctggcttgct tgaggttctt gccaaatttt tgcgccccaa tatggtatta
    16681 ataaaacttg atttaccaac atttgaacgt ccagcgaggg caatttctgg caaatcatct
    16741 tgggggtaat gagatttatt ggcagcgctc aataaaattg aggcgttatg ggtatttaag
    16801 acttgttctt cagccattat ttctccttaa gctgtctcta aaacgggttt tgacttgcct
    16861 tcgacagcag ccttggtgat acgcactttt gtgacatctt cttggcttgg aatttcaaac
    16921 atgatgtcta acatcgtttc ttcgataata gaacgaagac cacgtgctcc tgtcttacgt
    16981 tcaatggctt tattggcaat ggcttctaag gcttccttat caaatgccaa ttcgacgcca
    17041 tcgtaagaaa gaagagcctg atattgcttg accagggcat ttcttggttc tgtcaaaatt
    17101 tgaatcaaat ctgatgtgtt tagttgttca agggctgcca caactggtaa acgaccaata
    17161 aattctggaa taagcccaaa cttttgaata tcttctgaaa taatttcttg catataagaa
    17221 gcattgtcat caattttacg gctgttttga ccaaaaccaa taactttttc acctaaacgt
    17281 tgtttgacaa tctcctcgat gccatcaaaa gccccgccaa caataaacaa gatatttttt
    17341 gtatcaattt ggatcatttc ttgattaggg tgcttccgcc caccttgtgg gggaacactt
    17401 gctaccgtac cttcaataat tttaagaagg gcttgctgta caccttcacc agatacatca
    17461 cgtgtgatag atacgttctc acctttttta gcaatcttat ctatttcatc aacataaata
    17521 ataccacgct ctgctcgttc gacattatag tcagcagcct gaatcagttt gagtaaaata
    17581 ttttccacat cttctccaac ataccctgct tcagtcaaag aagttgcatc tgcaatagca
    17641 aatggtacat tgaggctttt agccagagtt tgtgctaaga aggtttttcc tgaacctgtt
    17701 ggtccaatca tcaaaatgtt ggacttttgt aaatccacat catcgtcatc acgactttct
    17761 gtaaacgaga cacgcttata atgattgtac acagcaactg ataaagcacg tttagcacga
    17821 tcttgaccaa ccacatattg atttaaaaca tcaaggagct cttttggttt tggaacttct
    17881 gtcaaatcgg caaggacttc ttcagccaat tcttctttta taatttcttg tgataaagct
    17941 acgcattcat tgcagatgaa aacattattt cctgcgataa tttttttaac gtcatcctgg
    18001 cttttaccac aaaatgaaca gtatacttta atatcgttag ttctacttcc tgccatttct
    18061 tataattctc ttactttctc ttatctttta ctgaatttta atattagtca atgtgttgta
    18121 ttggtttttg gtgattcttg cttgatagct aaatcttcac cagtgctgtc tttgcaagtc
    18181 gcatctcaaa acaatgtacc atagaaggcg tgaatactat taaccagatt agtaaacgca
    18241 tttaataaga acagacttcc taagccataa cgattctttt taaaagctgg gatggcacaa
    18301 agaacacaaa tcacgcacaa aaaagccgta aatactccaa aaatactacg ttgcatcgct
    18361 tatcatctcc tcagactatt tgtgttttaa agcagtaacg gtaaaatcat aaggattttt
    18421 agcgtctcga gcatagaacg tttggctttc ttgcgtgaaa tgactaaaat ctagattggg
    18481 tcggtaggta tctcctttaa aacgatgatg gataactgtt tttatgatac gatcaaaata
    18541 accattaaac gcttctaaaa ccttattccc accaatgata taaagtgttt tatcctgcgc
    18601 atggtaccac tccaagactt tttcaatact agtcattgtc aacacctcat ctacttgata
    18661 atctctattt cttgtcatga caagggtttg acgttgagga agtcttttgc aattcattcc
    18721 ttcaaaagtc acacggccca ttaagattgc ttgatgtagc gttgtatttt taaaatgttc
    18781 taactctttt ggtaaatacc atggtaactt acccgcaaca ccaataagcc ctgcttcatc
    18841 ctctgcccaa atagcaataa tttcctttgt cattaattat ttccttcatt ttaaactcta
    18901 tttattttac caaatttatg aacaaaatgc tcacaaaaaa tctaaataaa gtttaaatag
    18961 caaggtcaaa gtgcaactga ggcttcactg gatcataatt ttgtaattca aaatcatctg
    19021 gtttaatatc aaagaaatta gtcccatctg gaacatttaa aacaagctta ggctgactag
    19081 caactggctg tcgttttagt aattcttgag cctgatcaaa ttggttgtca taaatatgta
    19141 aattgttaac aaaataaaag aacttaccta ttttccatcc aaaatgttta gcaatcatca
    19201 tctgcaaggc aacgtattgc atggcattga tgtgatgagc aactaatatg tcattagaac
    19261 gttgcgtcaa actagcatct aaataaagat cttcccctac acgtctaaca tcaaacatga
    19321 tttgaaaggc acatggcaac aacccttttg tctcctcaaa tgcttcatag tcccagagag
    19381 aaatgacatt acgacgattc caaggatttt ctgctaattg ctttagtatt tttgagatga
    19441 tatcatgttt tttgactaca gcaccataac gttgtccaat agtacgtgtc tggtcaactt
    19501 cccattcatt ccaataatga acattatatt tagcttctag cacatctaaa ctgttagact
    19561 gatcttgata tatccaaaat aattccttta tagcagattt aattggaatg ggtcgtaaag
    19621 ttgtgatggg aaactctcct ttagctaaat catattcagc aaacgcccca gtaatatact
    19681 tagaatgagc tgttcgacca tctttatatt taggacgtgc ttgctcactc aatgatcctt
    19741 cgtttataat tttttgaata ttagctttaa aaatctggtc agcttttgtc atctctaata
    19801 acctttctgt aagcatactt catactattc taactaattt taccaaaaaa taccagaata
    19861 aataaacatt cgaaaaactt catgtggtca tgaacatttt aactattaaa ggataaaaca
    19921 aataacttta tcagtctaat tttgcagtaa aatgtgatag aatgggtaag actataaaaa
    19981 taactaaaag aaggacaaat atgacaattg gaattgataa gattggtttt gcaaccagtc
    20041 aatatgtctt gaaattggaa gatttagcgc ttgcacgcca agtggatcca gcaaaattta
    20101 gtcaagggct actcattgag tcttttagtg tggcaccaat cactgaagac attattactt
    20161 tagctgcttc tgcagcagat caaatcttaa ccgacgaaga tcgagctaag attgatatgg
    20221 ttattttggc aactgaatcg agtactgatc agtcaaaggc atcagctatc tatgtacatc
    20281 acttagttgg tatccagcct tttgcacgtt cctttgaagt aaaacaagcc tgctatagcg
    20341 caactgctgc tctagactat gctaaactgc atgtggcttc taagccagat tctcgtgtcc
    20401 ttgttattgc tagtgatatt gctagatacg gtgtaggatc tcctggggaa tcgactcaag
    20461 gctctggtag tattgctctt ttggtaactg ctaaccctcg tattcttgct ctaaataaag
    20521 ataatgtggc tcaaactagg gatattatgg acttttggag gcctaactat agtttcacac
    20581 cttatgttga tggtatttac tctaccaagc aatatctcaa ttgcttagaa accacgtggc
    20641 aagcttatca gaaaagagaa aaccttcagt tatctgattt tgctgcagtt tgtttccata
    20701 ttccatttcc caagttagcc ctaaaaggtc taaataacat tatggataac acagtacctc
    20761 ctgaacacag ggaaaaacta atagaagcct ttcaagcttc tattacttat agcaaacaaa
    20821 ttggaaatat ttatactggc tcactttatc taggattgtt atctttactt gaaaatagta
    20881 aagtattaca atctggagat aaaattggtt tttttagcta tggttccggt gccgtaagtg
    20941 aattttattc cggtcagtta gttgctgggt acgataaaat gttaatgact aatcgacaag
    21001 ctttactgga tcaacgaaca cgtctttccg tttctaaata cgaagacctt ttctacgaac
    21061 aagtccaatt agatgataat ggtaatgcca attttgacat ttacttaact ggaaaatttg
    21121 ctctaacagc catcaaggag catcaaagga tctatcatac caatgacaaa aactaatctt
    21181 aactggagcg gtttttcaaa gaaaacattc gaagaacgcc tccaacttat cgaaaaattt
    21241 aaactactta atgctgaaaa cttaaatcaa ctcaaaacag acgttctttt gcctatccaa
    21301 acagctaatc aaatgactga aaatgtctta ggacgattgg ctttgccctt tagcatagct
    21361 cctgattttc ttgtcaacgg ttcaacttat cagatgcctt ttgtcacgga agaaccttct
    21421 gttgttgctg cagcatcttt cgcagcaaaa ctaatcaaac gctcaggtgg ttttaaagct
    21481 caaaccctaa accgacaaat gattggtcaa attgttcttt acgatatcga ccaaatagat
    21541 aacgctaaag ccgccatcct tcataaaaca aaaaagctaa ttgcattggc aaataaagct
    21601 tatccttcca ttgttaaaag aggtggaggc gctagaacca ttcatttgga agaaaaagga
    21661 gagtttttga ttttctatct gactgttgat acccaagaag ctatgggagc aaatatggtc
    21721 aatactatga tggaagctct tgttcctgat ttaacaagac tgtctaaggg gcattgtcta
    21781 atggcgattt tatctaatta cgcaacagag tcgcttgtta ctactagttg tgagattccc
    21841 gtgcgccttt tagatcgcga taaaacaaaa tccctacagt tagctcaaaa aatagagcta
    21901 gccagccgac tagctcaagt agatccttac cgggctacta ctcataataa aggtattttt
    21961 aatggcattg atgcagtggt aatagccaca ggaaatgact ggcgtgctat tgaagcaggg
    22021 gcccatgctt atgcctcaag aaatggtagc tatcaaggac ttagtcagtg gcattttgac
    22081 caagataaac aagttctgct tggccaaatg accctcccta tgcctattgc tagtaagggg
    22141 ggatctatcg ggcttaaccc tactgtttct atcgcacatg atcttcttaa tcaacctgat
    22201 gccaaaacat tagcccaatt gattgcatct gtggggttag ctcaaaactt tgctgcacta
    22261 aaagctctga cctcatctgg catccaagct ggtcacatga aactacatgc gaaatcatta
    22321 gctcttttgg cgggggcaac ccaagacgaa attgctcctt tagttaatgc tttactagct
    22381 gataaaccaa taaatctaga aaaagcacat ttttacttat cccagctaag acagtcttag
    22441 atttaaacaa ctaatataag gcaaacaccc atgtaaacaa ttggtttaca tgggtgttta
    22501 atctttgttt ctatacatac aagtcttaga aatagtctcc ataacatact ctatttactc
    22561 atctactcta ttctgagttt gatgaggtat ttataaatat tttatattat gttctaaaaa
    22621 agctctatca tctttgtagt aggtggcact attgtagagg tgatgaagcc taattgacct
    22681 gctgcaagcg tccatatagt aagtagtcga ctccctttaa ttctttaata gttttacagt
    22741 caagagcaca cataatgatt tttaattctt ctttccagcc gttaacgata gcaatcacac
    22801 gctcggttgg gtatttttcg accaattcta aaacggtgcg tgagagtccc actgcacgtg
    22861 ctcctaggac gaaacattta atcatgtcca aggggtgtct gacaccaccc gaagctaaga
    22921 tttccacttg gtccatcagt ccttgtgcat ttagcaagca ctgaacggtg gtttgtcccc
    22981 aatcgtttaa gtaagagcgg tctcctcctc tttgattttc aatataggca aatgaggtcc
    23041 ctcctcttcc tgaaatatca aaggtttgaa tgcctaggtc atgtgctagc ttgatactat
    23101 tgacatccat gccaaaacca acttctttga gaatgacagg aactggtatt tgactagcgt
    23161 attcagcgag gtgttttttc caggtatgaa agacgcgctc accctctggc atcagcaact
    23221 cttgcatcac attcacatga acctgtaaaa agaggggctg catttcttga accgtttgtt
    23281 gtcctagcgc cacaggttta tctagaccaa tattcgtggc tagtttcaag ttatctgcca
    23341 cctcatgtaa acgataggaa tcgtcgttag gattttttaa agcagcgcta taagaccctg
    23401 tcaccatgac aatccctgtt gctgctgcta ctttggccaa tttttcattg acagctttgc
    23461 ctttttgact tcctcctgtc atggcattga tgtaaaaggg aaagtcgaag tcttgcccag
    23521 caaaatgagt actgagatca atatcagaca aatcatagct aggtaaggaa tggtgtatga
    23581 gttctatgtc atcaaaagca ctataaggcg attggtactt gagagcatat ttgatgtgat
    23641 catctttacg gttagtcatt ctctccccac ctttcttgat aaagtaatgc gatatcagct
    23701 tcttgccatt tggaaataag ggtatctcta gcatcctgat taaaggcaag cgcgatgcca
    23761 caatctccac caccagaacc tgaagattta gcaacagcat cttgcttctg acaagcagct
    23821 accaaggtta ctagcttagg atggtagata gctggatgaa gctcttttag gagatgactt
    23881 gctcctgcta aacttttctt gagttcttcc ttatgacctt cttgcaaagc taccatagct
    23941 gattgcgtta gctggtaact tgttcttaag aaagctgggg taatgctcgc tgtcacttgt
    24001 tgaatcatct gccttgaaat agcaggtatt ttagtccagc caaccaaaaa gtcacaaggc
    24061 agggctggtt gaatgacttg gatatggtaa ccccaatctt tgacgagaag tttttttaag
    24121 ggcatggtct gcagccagtt actgacctgt tctcggtcaa aggaggtata ggcgactaaa
    24181 gtctggtaag cgatacaggc aatatccccc atagacccat tatctccttg cttaagcaag
    24241 gtataagccg ctagtttaaa gagtaactct ggggttaaag tgatctgata ataggccgat
    24301 aaggccttta aggttaagag ggtgacgcta ccacttgaac caatgccaaa ttttttgcca
    24361 tcgcgctcca tttttcctgt tatgattagg gaaaatggct ccagttggtc aatcgactgt
    24421 cctagatagt cagcaaaggt tttaaccgtt gcttgaatca gtgcataaga ggcatcgggt
    24481 gtcatgcccg ctttatgggc aaacatatct gaagctaatt gaatatgggc tgctgggcta
    24541 atttctgctg tcatcatcag tggaataaag tgaattaagg ctttttgtcc tggtgttaag
    24601 atagcatatt cgcctgtgag gtatagtttc ccacctgttt gcacacaata attagacatc
    24661 tggtaaatcc tttgtttttg aaacgataat acggtagttc ttgccaagtc gttctgccag
    24721 ttgagccaag tctttttcta aacataggac cttcacattt ggacctgcgt ccatggtaaa
    24781 ataacaagca aaaccttctt gacgcagttc tttcacagcc tccatagcct ggtaagactc
    24841 ttttgttagg taagaaaaag gaggattggc tgtctttgtc gtggcatgca tggccaaggc
    24901 attagcttct gttaactgac caactttctc aaaattatta gttttgagat aggtaagcat
    24961 atgttggtaa tcgattgccg attgttctac ccactcatca aatgtagttg aggtatcgcg
    25021 gcataacttc atgccctctc ggctagaaat tggctttttc gcagcattta agaccagcat
    25081 aatcatggcc attttcaagt cagtctcaac cttgtaaata gcaccactat ctttgtccca
    25141 agcagcgact gggccaaaaa aagaacgaga agatgatcct gaggcgaact tagccttttg
    25201 agctaaagct ttctgatcta gctgggtgtt aaatagttgg tcacaggctt taaccaaggc
    25261 tgataagcca ctggaacttg atgataaacc tgcagctgtt ggcatattat tttgagtttc
    25321 catctttaca aaagcctgac caggttggcg aaattggtca atgatagcag aaattttggt
    25381 atgttcttcg tcattttgca agacaccgtt aatgtaaaac tgatcactgg ttgcagtatc
    25441 tggtaagaag gaaatgctgg ttgtggtgaa catgttttcc aaagtcaaag aaatgctaga
    25501 ggtcgaagga atcatcttag cttgattctc ttttccccaa tatttgataa tagcaatgtt
    25561 agcataggat gttacggtta taacatttgg atccacgtgt ttacggctcc ttcttctttt
    25621 aatctgtgac tgattttttc ggccatgtct ttggtatctg ctagggcaat catacagcca
    25681 cccaagccac cgcctgtcat cttagcgcct aaagcacctg ctcttagggc agcctccaca
    25741 agttggtcag ccttactgat gctaacgcca atggccttta aagcagagtg cgcttgtgtc
    25801 atgagctgac cgatagcaac cttatttttt tggttaatcg ctctttcaag ggcttgtgtc
    25861 aaagctccta gtttagccag atagggcaaa ttcgtttcct caaactgtgc taccttattg
    25921 acggcctcac gtgtatgacc gtgaatccct gtatctgcaa tgataagata accatttaag
    25981 gcgatttcga tagtttcaaa gccaatgttt cggataaact taatggcatg gtcactaagg
    26041 catgtcttgg catctaaacc actaggattg gtgtgggcaa taatttctgc cttgttgact
    26101 aaaatttcca acaaatcatc cgagaggggt tcttgacaat aagaaaaaac ggctctaata
    26161 gctgcaatag aaacggctgc cgaagacccc ataccacgct tttgtggcac ttgtgaaaca
    26221 atctcataag caattggttc ttgtagtcgc tgcaaataat ccaaggcagc ataaatggct
    26281 gttgatagag tatcataaaa atcaaagacc aatggcttat cagctggaaa aatatgacaa
    26341 accacctcaa tatctgttaa aggcaaagca atagctgggt agccatacac aacagcatgc
    26401 tcacctatca aaatgatctt actgtgtgcc ttaccatatc caatgttttc attcattttt
    26461 tatcttttca ttactaattc ttctaaactt ttaccttact attttacact aaatgattag
    26521 aaaatgcgat gatatatctt tttaaaatca tttcttcact gaaattaaca ataaagacta
    26581 tctactcttt ttaggatcat aacaaaaatt ttcttatttc aaactacctt ctttaatcac
    26641 tcttctacta aattaaacgt taaaaccagc ctcatgggct ggttaagcat cgtttattac
    26701 ctttacctag acattattac tagctaaagg tactgaaaaa tgtttaagtc aaatcaccac
    26761 tgtaaaaaca atagcatcgt ttttataatt tacagttatc gttcctttaa ataacttaac
    26821 catactttct gccatagata aaccaattcc ataacctttt tctttgctat tatgggattc
    26881 gtcttcgcga taaaagcgtt caaaaaagcg gctgtaatca atggattttc cttccaaata
    26941 ggtattagaa acttctaatt tcgctcgttt tcgtcttctt ccaatagtgg ttaaagatac
    27001 cttgaccaag cctttaggat cacaatattt attggcatta tcaactaaaa ttgtcacaag
    27061 ttcaaacaat gacttttcct ccgctttaat cataatattc ggctgaatcg tcaaatcaaa
    27121 acgtttacca tctttcaaaa ccagactctt aaaatcttca gctgcatctt gagcaatagc
    27181 tgaaaaatct accatatgta ataccacatc tggctgttcc tccaaacgag ccaaagtaat
    27241 catttgatta atcaagcctg tcaatcgctt cacctgatca cttgtactct tggtccattc
    27301 tgattctcca gtcattaatt cgaccaattc attattggct gagataatgg ctagtggtgt
    27361 ttttaactcg tggcctgcat tagtaataaa gcgacgctgc ttctcataat tttggacaaa
    27421 aggtttgatg accataccgg aaaaaagact cactaaaaca acaaaaaaga taaatcctcc
    27481 aaaggccaac atcactgaaa cagctaataa atctcctaca ctacgaaaat aaaaggtagt
    27541 atctaaaatt acaaccagtt tttcttcatt tggcagctga gtaatcaagt acgaataaac
    27601 actatcttgg tgacggtaac tgcctttttc ttccccagac ttagcaaaaa gtctagcaaa
    27661 atattgggct tcttctctat ctaaagctga aatattagca gtattagaag aaagtagatg
    27721 tccattagca ttaaaaatga cactataata ccgaaactgg cttaggctat cttcagacag
    27781 tttcgttcca agtcgtttag agctttccgt agtgccaggt aatttacctt tatttgagga
    27841 aattaaatgt aaaatacggt taatttcttg ttgactttgg taacagcgtg ccgtgttaat
    27901 aataccaaca attgaactta aaataataaa aatggcaata gaagcaatca tgataaaacg
    27961 aatacggata cgattaaaca tgtcacctcc tatttttcta ataaacaata gctagtatct
    28021 ttatcacctg caataatgac atttgcttga atagctaata atttttgacg aagataagaa
    28081 atataaaccc aaacaataga agtatcataa tcttcttggt ctgaccaaac atgttggtaa
    28141 agcgttttag tatccaagta ctttccttga tttaacatta aaaaggccat taatttacct
    28201 tctttagaag ctaatcgtat agcattaccg gcactcaatt cttgctcatt aatatttaat
    28261 gtgacaccag caaattgtaa tacctgagga gtaaaacttt ctactcgtct ttccatcgac
    28321 cttaatctag ctaaaagttc ttttaatgag aaaggtttag tcagataatc atcagctccc
    28381 gcatctagtc cggtaacacg gtcattaatt tctgccatag ccgtcagcat aataatatgt
    28441 gagcaatttc ctgaagcgcg aatctccttt aaagcctcaa tgccagactt aatcggcatc
    28501 atgatatcta aaatcataat atcatatgca ttgtctttgg ctttatcaat tgcctcttga
    28561 ccgttaaaaa ccacatcaac gtcataacct tgatgagtca tggcagttgt caaaacatta
    28621 gacatctgcc attcgtcttc agctaacaaa attttcatgg ttactcttcc tccgtcgttt
    28681 cttgaatcaa ttgacgaatg gtttgcatgg taacatcaca agatgccaac tcgtctgcac
    28741 aacgctttaa ctctcttgta atcatttctg cattagcaac ttgatgtttg tacttcattt
    28801 gatgttccaa gctagcccaa gagtcttgag caatggttcg caactgcact tctataaaat
    28861 aacatccttt tttttcccct aaaatatctg gaaaatgtgt ttctaattcc aaaatgagat
    28921 gatatgatct atagccatta ggcttggcat ttaaaatata atctttttca gtgttaactg
    28981 acataccagg aatgcttttg agcaagtcta ccatccgata aatatcatca ataaaaccac
    29041 aaataatgcg aataccgata ctatctttaa tgatttttaa cgcagatttg cttgttagag
    29101 gaagctgttt gcgttgacat ttttcaatca tcgaagcttc cgatttaata cgggatgtaa
    29161 agtgttcata tagtttaaac cctgtttctt ttttgctttt gatattctca gcaataatca
    29221 catctgttat tgtctgtagt actaacggca agtacacttc aaatccgcta tatatagagc
    29281 tggtagaata atgttctagt ctttctttca tacgcttatt ataacaaatt ttctcaacaa
    29341 atgcttaaat ctctacaatg atcggttatc tttatttcta actatataac tgtaaatgat
    29401 ctttatcgtt tgtttttaaa tcgctttcat atattttttg tacgttattt tttaaaaata
    29461 ccattgaatt acaaacaaaa acatagtaaa cttgatctat aacgattacg ttaacttatt
    29521 aggagatttt atgaaaaaat attttatttt aaaaagtagt gtattgagta tcctgactag
    29581 ttttactcta ttagttacag acgttcaagc agatcaagtt gatgtgcaat tccttggcgt
    29641 caatgatttt cacggcgctc ttgataatac cggaacagct tacacaccaa gtggtaaaat
    29701 accaaatgct gggacggctg ctcaattagg tgcttatatg gatgacgctg agatagattt
    29761 caagcaagca aatcaagacg gaacaagtat acgtgttcaa gctggagata tggtcggagc
    29821 cagtcctgct aactctgcac ttttacaaga tgagcctact gtgaaagtct ttaacaaaat
    29881 gaaatttgaa tatggcactc ttggtaatca tgaatttgac gaaggactag atgaatttaa
    29941 ccgtatcatg acaggtcaag cgcctgatcc tgaatcaaca attaatgata tcaccaaaca
    30001 atatgagcac gaagcttcgc atcaaaccat cgtcattgct aatgtcattg ataaaaaaac
    30061 caatgatatc ccctatggtt ggaaacctta tgctataaaa gacatagcca ttaatgacaa
    30121 aatcgttaag attggcttca ttggtgttgt gactacagag attccaaatc tcgttttaaa
    30181 gcaaaactat gaacactatc aatttttaga tgtagctgaa accattgcca aatatgctaa
    30241 agaactacaa gaacaacatg ttcatgctat tgtggtttta gctcatgttc ctgcaacaag
    30301 taaagatggt gttgttgatc atgaaatggc tacggttatg gaaaaagtga accaaatcta
    30361 tcccgaacat agcattgata ttatttttgc aggacataat catcaataca ctaatggaac
    30421 tatcggtaaa acacgtatcg ttcaagccct ctctcaagga aaagcttatg cagatgtccg
    30481 tggaacgcta gatactgata ccaatgattt tatgacaact ccatcagcaa atgttgttgc
    30541 tgtagcacca ggtatcaaaa cagaaaattc agatatcaaa gctataataa atcatgctaa
    30601 tgatattgtt aaaacagtta ctgaacgaaa aatcggaact gcaactaatt cttcaactat
    30661 ttctaaaaca gaaaatattg ataaagaatc tcctgtcggt aacttagtaa caacggctca
    30721 gcttactatt gctaagaaaa cttttccaac tgttgacttt gctatgacca ataatggtgg
    30781 tattcgaagt gacctagttg tcaaaaatga ccggaccatc acctggggag ctgcacaggc
    30841 tgtacaacca tttggtaata tccttcaagt cattcaaatg actggtcaac acatttacga
    30901 tgtcctaaat cagcaatacg atgaaaacca gacctatttt cttcaaatgt caggtttaac
    30961 atacacttat acagataatg atcctaagaa ctctgatacc cccttcaaga tagttaaggt
    31021 ttataaagac aatgatgaag aaattaactt aacaactact tacaccgttg ttgtcaacga
    31081 ctttctttat ggtggtggtg atggcttttc agcatttaaa aaagctaaat taatcggagc
    31141 tattaacaca gatactgaag ctttcatcac atatatcaca aatttagaag catcaggtaa
    31201 aactgttaat gctactataa aaggggttaa aaattatgta acttcaaacc ttgaaagttc
    31261 gacaaaagtt aatagtgctg gtaaacacag tatcattagt aaggttttta gaaatcgtga
    31321 tggcaatata gtgtctagtg aagtcatttc agaccttttg acttctactg aaaacactaa
    31381 taacagcctt ggcaaaaaag aaacaacgac aaacaaaaat actatctcta gttccactct
    31441 tccaataaca ggggacaatt ataaaatgtc tcctattatg acaatccttg ccttgataag
    31501 cttaggtgga ctaaacgctt ttattaaaaa aaggaaatcc tagcgtttac tagtaatcga
    31561 tcacccttat ataatcaggc atctttgcca aaaaaaccta aagcgtccta ctctaggttt
    31621 tttgttaaat taaaatacct tctagatgat ctaattcgtg ctggcatatt tgagcagtta
    31681 agcctgttaa gcttaatcgc tttggtcgcc aattatggtc caaatactca acagtaatct
    31741 tatcataccg ctgtgttttg cgatagccag ataacgacaa acaagattct ttagtttggt
    31801 aaattccctt tttagaaacc atcacaggat taaacataac caaatcaata aatcccatac
    31861 tcacaataac aatgcgcttt tgttcaccaa tcatattggc agccatccca agacattcct
    31921 gtctataaaa ggctaaggta tcttgtaaat cttggccaat ccatagatct tctttcttgg
    31981 cgacttgcgc tttttgctgt aataaaaaat gatctgttat gatttctcta atcattctta
    32041 tctccttaaa ccttcttttt aattcataaa ctacatgttc aatggactat tatcaccata
    32101 tgatagactt agtatcatct gtttaaaaca tcaggtgatt ccttatttca agatatcttg
    32161 ggcaacttta tgaaattctg caatatgagt accaaataaa aattgacctg catcagcaga
    32221 ttgttgctaa gttctcatca caatattatc gaatttactg tctgcttctt caaatgtcta
    32281 agagagatag ttattgcttt gtgagatttt caaaccagat actgctttct cttgcatttg
    32341 caaccttaac aggtccaaat aaaacacctg ctgtttgaaa tactttaata gctgatatgt
    32401 tgttaatagt tagtattata aattttctga atatttctgt caagtttttc agttgactta
    32461 acttttttac ttgatttttc ctcacgtaat aatagaaaag aagcgccata atgtaaacta
    32521 caccccaaac gttagataaa aaaatctaac gtttggggtg tttttgtatg acattaagct
    32581 atgaagataa gctagatatt tagcgctaaa aaaaccgagg gaactccgtt tgaaataagc
    32641 atctctgcaa agaagaagac aaaaaaccat tataaagaat ggacaaagac gagttctgat
    32701 tagattttct tttaagaacg gctaaagtga ctcgttctac ctactattat catcgattat
    32761 tgcaacaata aacgtatcaa aataaaacga aaaggactta gtcctctaca acacagaact
    32821 aaatccttta cttcaaatag agtagccaac ttttggggct cagtgcaaga gcacttcttt
    32881 tctattatca cttgtttatt ataaacataa cattaccata gtattcttat atgtctagtc
    32941 cactcaaata ctcaaaccgt tcatacgcca ataataaatc attattgtgc tgatcgagtt
    33001 ccttttgtaa ttgagctaac tggtcataat cgctaactac agttaacatt tggttttcaa
    33061 tttcttcaat attagcctca atagttgcta ttttatcttc tatctgagcc cattcttgtt
    33121 tttcaaggta ggacatgcgc tttctttcct ctttttgagg aagtggcact tcttcagtga
    33181 ctgttgtttt aaccaagtca gcctcaactg tttctttttc aaaaactttt tcatcaaggt
    33241 aatcactgta attgccataa aaaacacgaa tatcgccttc ttcaaaggct aaaatcttag
    33301 tagctacttt gtctaggaaa taacgatcgt gactaaccgt aatgactggt cctgcaaagt
    33361 tagctaaaaa gttttctaag accgtcaagg tggcaatgtc taaatcattt gttggctcat
    33421 caaggagaag aacatttggc ttttcaatga gcagttttag caagtagagc cgttttttct
    33481 ccccaccaga taatttagca atcagcgtgc catgacttga tcttggaaaa agaaattgtt
    33541 ctaaaagctc actgatactc gttgttccca cacttgtttt aacctcatca gccacttctt
    33601 gaaggtaatt aatgacccgt ttggtctcat ccatatcttt gagctgctga gagaaataac
    33661 ctacacgaat agtatctcca atatcaagct tcccagaagt tggttcaaga tctccattaa
    33721 ttaaattcaa cagggtagat tttccgacgc cgttatctcc aacaattcca atacgatctt
    33781 tattttgaat aatcaagtta aaatccttaa tcaactgtcg gtcgccataa gcaaaagaaa
    33841 ggtcttcaaa gtgaatcacc ttcttcccaa ttcggctcgt ttcgaaagcc atctccaatt
    33901 tatctgcaga actgtcttgg tgaacttctt ttttcaagtc agtgaaacga ttgattctag
    33961 cctgctgttt ggttgcacgc gcctgtggct gcgtcctcat ccaagctaat tcttgtttat
    34021 agagttgctt cttcttgtgt aaattagcag catctcgttc gtcttgttct gcttttaagc
    34081 gcacatagtc ttggtaattg ccttgatatt ctgtcagtcc cgctttatcc aattcaaaaa
    34141 tacgggtagc cacatgatca aggaaataac ggtcatgggt aataaaaagg acggtttttt
    34201 tagctgtctt gagataggtt gttaaccaag cgatggtgtc aatatcgaga tggttggtcg
    34261 gctcatccaa caagagtaag tcagcagctc ctagcaatac ttgagctaac tggacacgtc
    34321 ttctcatacc acctgatagg tctcccactt tttgttccaa atccgtgatg cctaattttg
    34381 ataggactgt tttgacatca ctttcaatag accaagcatc taagcgatcc atttcagaca
    34441 tgagggactc taaggtctct tgtttatctt cagtataatc cgccatcaat agttcatatt
    34501 gacgaatcag ttgaatcgcc ttaacatcag atgacaatac cgtatctaaa acagaagctg
    34561 catcgttaaa ttcagggtct tgtgttaagt aagcgatttt gtaatcattg gctttagaaa
    34621 atggtgaatg gtctccgtca aaaccaagcc ttcccgacaa cacatctaaa agagttgttt
    34681 ttcctgttcc attaatccca ataatcccaa tacggtcaaa gtcatgaata ataaaggaaa
    34741 tatcttgaaa gacggtctta tctcccaccg tttttgttaa tttctccacc aaaaaatggc
    34801 tcatgttgct aattcctctc taacaaatgc ttcaattgta gtgaaatcat tatctaggcg
    34861 cccctctaca atcgctaatt caactttctc aagcataagc cctagctgag gacctggttt
    34921 catcccaaaa tccttaatca ggtgagaacc attaaggacg atatcgtgtt tgtcatgaat
    34981 aaccagtgcc tgatctaaag tattaatatg atccatgtca acggataagc tttgagcttt
    35041 tcggaggtct tccactagac tcgccatttt cttgccgtac tggtaaatat ccaatttttc
    35101 aaaagatctt tcctgacgaa ttctataaag agcaatcaac tttgtgacat aacgctgaaa
    35161 atcatttgaa gtcttccatg cttttaggaa gcttttagga tcctcaatgg ctaaactaat
    35221 catcacataa gcccaagctt ggtgatgatc actaaaggta aagttatctt tcaaagaaac
    35281 tatcagatga ttcaagcctg cttcctgctg cttcaagcct ggtaaatagt cataagcctg
    35341 acaagcaatc atggcagaaa tcccttttcg ccagtgcggt gccatcaata atttatcaaa
    35401 ttcagtaaaa gaacgttcca cagaaatctt ttccaataga ggtgaatggc tcctcatagc
    35461 ttcaaaagtt gtagcttcaa tgtcaaaatc cagactcgcc gcaaatcgaa agcctctcat
    35521 aatgcgtagt gcatcttctt caaaacgttc ctctgcttta cccactgctc gtaaccgttt
    35581 ttgctttaaa tcaatgagtc ctctaaattt atcaataact ttaccatttt catccaaggc
    35641 caaggcattg acggtaaagt ctcttcgttt taagtcttcc tctaaagagc gcacaaaaga
    35701 gacctgacta ggacggcgat aatcaacata gacatcttct gtcctaaagg ttgtgatttc
    35761 atactcaccg ccattttcaa gcacgagcac tgtaccatgt tcaatgccaa catcgacagt
    35821 tctgttaaaa atcgctttag tctcttcagg ataggaacta gttgcaatat ctacatcatg
    35881 aatgggacgc tcgagtaaaa catctctgac gcttcctccc acaaaatagg cttcataacc
    35941 agcttctttt attttagtca atatgggtaa agccttctga aactcagaag gcattgtcat
    36001 taatttcata cgttgttttc taacctatca tccaactagc ccaatctaaa gtgtgattag
    36061 gctacttggg ttctatcaca ttttgttatt gttttagtga ttcttgcaat taactatttt
    36121 ttctaatcga caattaaagc ctcggtgtta cgccaaatgc aatggctcct tctcctaaat
    36181 gagtagcaat caccgctcca aaatgaacct cttcaatgtc atattgataa ccactgtctt
    36241 gtaagagtcg tttcaaataa tcagctttgt cttgtgcttt tgagtgaata ataaacacat
    36301 tatactgacc gtctgctatc aagtcattta aaatctcaac caagcgtttc atggctttct
    36361 tttctgttct cactttttca taaacaacga tttttccctc ttcatcaaag cgtaaaatag
    36421 gtttaatact caaaagattt ccaagaagag cagacccatt tgacaggcgt ccacctttaa
    36481 ccagatgatt aaggtcatca accataataa aggctgtcgt cccatcaatc tgttcttgca
    36541 gcttgtttaa aatagcttga aatgtcattc cttgacgtga ccaatctagc acatttttta
    36601 ccatactacc taaaggagca gatgtgatct tactgtctgg aaatgccatt tcaatctcag
    36661 gatgttcttc agctaaaaat tgaatatttt gccaaaagcc cgagattcct ccagctaaga
    36721 acaagccaat aacatgtgta taacccttag aagacaaaag tcctaaaaga ttatctagtt
    36781 cagataaact tggctgactt gtcttgggaa gattttggga gtcagccatc ttttgataaa
    36841 aatcatctat actcaaattt cgaccttcaa aataggtctc atcgtcaatg ataactggta
    36901 tatcaaggct aaaaatagct ttatcttgtt tcagatctgt tggtagtgtt gctgtactgt
    36961 cagtaattac tgctaatttc attaattttt aaactccaaa tgaatacctg gacgatccaa
    37021 ggcaatttct gtgacttcat aagtcaatcg cttaaccata tctagcaaag gagcagctaa
    37081 ggattcaact tcctcttgcg taaattcgct tggtttatcc actaaacgat ctaaaatacg
    37141 aaccatttgt gagatgaccc cactaataac aaattcctct ttgacaataa caaattgcaa
    37201 tacagataca attactgttt ctttttgctg ctcatcttta tcaatcaact gaaaagtcac
    37261 ttcaaaattg gtctctggtg ttccgttttc tttttcccac tctaaatttc tagcatcata
    37321 atggtactgg ttgacaaatt ctttttcacg aactaattgc attttttatt ctccttggta
    37381 tcaatatgat ccattatagc atagatttga aaattattaa agtagcccct aaactactat
    37441 tttcgcataa cgttttaaac agtgctatct ctcgaacaga catctatttt ttcacctatt
    37501 tatatttagt cgtccttata ctgacattat atcaaaaaaa cacccgttag tggtcttgta
    37561 ctgcacctca attaaaacag aaccactggt caggtaagtt ttaagtccag gataaaaagg
    37621 tttatcacca aggcctcatc atgcttagcc aagtatttcg aactagcttg tcttagctct
    37681 agtcgctcaa acgtaaatcc taggcgttca atccgccgca aaacctctcc aactaaccca
    37741 tacttaaacc catcgggctt aatcatcgct ccgcccttct tctcctttta tccattataa
    37801 aataaaaacg ttttaacaga caaaaaatag gaaagtacca gactattgga tttatttttt
    37861 tatctcaaac tccattaacg atgttgagtt aaaggcattc aaaaccacat agatcgtaag
    37921 ctaacaagat tttttatcaa ttgaacctat tgtccccagt tatacacgac ctcttctgga
    37981 tgaggtcttt ttttatttgt ctaatttcat caacgcttct tcccctcttt cttctatcac
    38041 agctctccta ttgctcactt cctcatgcgg aaacatatca tcaaaaaacc gtccattttt
    38101 aagcacaacc actactgtat cacttgtgat atctccattg tcaatcgctt gtttacgttt
    38161 attaaaaatt atttaaaaaa ttaaatatta ttttaaaaac ttgcaacaat agatgtctat
    38221 attatataat ttatttataa taaaattata tagaaaaagg tactcttatg agaaaaagat
    38281 gctattcaac ttcagctgta gtattggcag cagtgacttt atttgctcta tcggtagatc
    38341 gcggtgttat agcagatagt ttttctgcta atcaagagat tagatattcg gaagtaacac
    38401 cttatcatgt tacttccgtt tggaccaaag gagttactcc tccagcaaaa ttcactcaag
    38461 gcgaagatgt ttttcacgct ccttatgttg ctaaccaagg atggtatgat attaccaaaa
    38521 cattcaatgg aaaagacgac cttctttgcg gggctgccac agcagggaat atgcttcact
    38581 ggtggttcga tcaaaacaaa gaaaaaattg aagcatatct aaaaaaacac ccagataaac
    38641 aaaaaatcat gtttggtgat caagaattat tggatgtaag aaaagttatt aatactaaag
    38701 gtgaccaaac aaatagcgag ctttttaatt atttccgaga taaagctttc cccggtttgt
    38761 cagcacgccg aattggagtt atgcctgatc ttgttttaga tatgtttatc aatggttatt
    38821 acttaaatgt ttataagaca cagactactg atgtcaatag aacctatcaa gagaaagatc
    38881 gccgaggtgg tatttttgac gctgtattta caagaggtga tcaaagtaag ctattgacaa
    38941 gtcgtcatga ttttaaagaa aaaactctca aagaaatcag tgatctcatt aagaaagagt
    39001 taaccgaagg caaggctcta ggcctatcac acacctacgc taacgtacgc atcaaccatg
    39061 ttataaacct gtggggagct gacttcgatt ctaacgggaa ccttgaagct atttatgtaa
    39121 cagactctga tagtaatgca tctattggta tgaagaaata ctttgttggt gttaattccg
    39181 ctggaaaagt agctatttct gctaaagaaa taaaagaaga taatattggt gctcaagtac
    39241 tagggttatt tacactttca acagggcaag atagttggaa tcagaccaat taaagcgtat
    39301 caataagaaa gattacattc aacagatgat ggtattctaa ggactaatac tattgcaggg
    39361 aattttttta tagatgggca acagcaaaaa acattaataa atcctataaa aatcgataag
    39421 gatattgtta cgattcaaga gttcgatttt aaaataagaa aatttttgat ggaatcaaaa
    39481 gaaattcatt tgactaagtc tccttatata agggggagtt tagaaattca cagtaaaaat
    39541 aggaaacatg aaaaaatcaa tttatatgac gcaaaaccca atagcactag atctgatgtc
    39601 ttaaaaaaat ataaaggcaa taagactata aacatgaaag atttcagcca ttttgatatt
    39661 tatctttgga ctaaataagc taaaagcttt ggataaatat gatcaattga cctataataa
    39721 cattgatacc aaatctaaaa ctgctcagat tgaattgcgc cccaaaagtt agacaaaaaa
    39781 tctaataatt ggggtgtttt tgtctggcat taagtttagc taataacctt gcttaaatca
    39841 cattaaacca ataatggaaa aaggcatctc caaataaatg ctatgatgga actatatgat
    39901 agagtgatca aggttggcaa tatcaacaca actattatca tcatttccta aactctaaag
    39961 gaattcgtcc gtctatgtca cgtaaaagaa acagtcctga caatagcatg atggaatctt
    40021 tctttggcat cttaaagtca gaaatgttct atggttatga gaataactat aaatcactag
    40081 aagacttaga ataagcgatt acaaatgaca ttgattatta caacgataaa catatcaaag
    40141 taaaactaaa aggatttagt tctgtacaat acagaactaa atcctttact taaaatagag
    40201 tatccagctt ttttggggtc agtgcaagca gattgttgtt agtgttacat taataagtca
    40261 tgcgtttagc ccaagcctca tcaactgcta gggtctccgc atcagtgtaa ttacgacgat
    40321 actcattcca aacataaccc gaagttgcta gaccagtttc ttgagctgag ctattagcaa
    40381 catcataagc cgtcaaacca taggttgcaa taatattatt tagttttaag ttataactgg
    40441 tgtctgtagc gtataagcca gttagagctg ctgtagcatc ttgatacgat agcgtgtttg
    40501 attttctagc acctatataa gtgctagaac ttagcaagtc tgcatagtca ttaagggagt
    40561 ctgcaatact tggataagct ctaaaggctt gatcaatcgt ataggtattg ccattaccat
    40621 catcttccca agttgacatc gtcacagaag aaccgttata ggcaccctta ataccgaaaa
    40681 aattataata aggtgcttga cttagacttg atttaccatt acttgattct aaaatcgctt
    40741 gtgctatcat aacagacgca taaagatcac gttcttgacc aatagtacta gcagttggac
    40801 caatttcatc aataaaatgt cgggttgaag aactggcgat agtctcagct gacacgtttg
    40861 aagttttatg agattgtctc attgcactat aagctcctaa acaagctgct agaacaaaaa
    40921 gactgataag tacaagctta cctttctttt ttgtcattat tcacatatcc ttttttatac
    40981 attttctatg tttctattat agcacacgaa cgtttaaatt aacttttcca cagataattt
    41041 aatgagattg ataacttttg tcttgaaatc gacatatttc ttctgatttt ttttaaaatt
    41101 gtggataact atttcattag accatcaaaa ttagtgagtt gataccattc aatcaattca
    41161 tttaatttgg tatggt
//
