LOCUS       NZ_LR134479            41905 bp    DNA     circular CON 23-AUG-2024
DEFINITION  Rothia aeria strain NCTC10207 chromosome 1, complete sequence.
ACCESSION   NZ_LR134479
VERSION     NZ_LR134479.1
KEYWORDS    RefSeq.
SOURCE      Rothia aeria
  ORGANISM  Rothia aeria
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Micrococcaceae; Rothia.
REFERENCE   1  (bases 1 to 2707814)
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (18-DEC-2018) WTSI, Pathogen Informatics, Wellcome Trust
            Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Taxonomic-Update-Statistics-START##
            This Genome (query)               :: GCA_900637985.1
            Current Name                      :: Rothia aeria
            Previous Name                     :: Rothia dentocariosa
            Date Updated                      :: 2020-07-31
            Analysis Type :: Average Nucleotide Identity (ANI)
            Analysis 1 (A1) :: Query vs. TYPE genome for current name
            A1 Genome (subject)               :: GCA_002355935.1
            A1 Name                           :: Rothia aeria
            A1 ANI                            :: 97.49%
            A1 Query Coverage                 :: 89.17%
            A1 Subject Coverage               :: 93.28%
            Analysis 2 (A2) :: Query vs. TYPE genome for previous name
            A2 Genome (subject)               :: GCA_900455895.1
            A2 Name                           :: Rothia dentocariosa
            A2 ANI                            :: 90.02%
            A2 Query Coverage                 :: 26.56%
            A2 Subject Coverage               :: 28.88%
            ##Taxonomic-Update-Statistics-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 02:12:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,382
            CDSs (total)                      :: 2,321
            Genes (coding)                    :: 2,312
            CDSs (with protein)               :: 2,312
            Genes (RNA)                       :: 61
            rRNAs                             :: 4, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 9
            CDSs (without protein)            :: 9
            Pseudo Genes (ambiguous residues) :: 0 of 9
            Pseudo Genes (frameshifted)       :: 2 of 9
            Pseudo Genes (incomplete)         :: 8 of 9
            Pseudo Genes (internal stop)      :: 0 of 9
            Pseudo Genes (multiple problems)  :: 1 of 9
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:04:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 246014
            Orig. end                         :: 287919
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR134479.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The organism was changed from 'Rothia dentocariosa' to 'Rothia
            aeria' in July  2020.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41905
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..41905
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="neighbouring"
                     /product="lassopeptide"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22327
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22327
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12327](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12327
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(17..460)
                     /locus_tag="EL250_RS01205"
                     /old_locus_tag="NCTC10207_00244"
     CDS             complement(17..460)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013398368.1"
                     /locus_tag="EL250_RS01205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00244"
                     /product="N-acetyltransferase"
                     /protein_id="WP_126499508.1"
                     /transl_table=11
                     /translation="MQYSILNAENSLPSTEELVELYDAVGWSVYTRTPERLVPMLAGSR
                     YLYVARENTAEGTERLIGLVRAVGDGQTIAYVQDLLVHPQAQRHGIGSALLGKIIADFD
                     REGIRQRFITTDIVDTPVIELYQRFGFTPVQDNGCVTLAKYVF"
     gene            complement(593..1123)
                     /locus_tag="EL250_RS01210"
                     /old_locus_tag="NCTC10207_00245"
     CDS             complement(593..1123)
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888559.1"
                     /locus_tag="EL250_RS01210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00245"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_037232996.1"
                     /transl_table=11
                     /translation="MSIENLRNALPSYAKDMNLNLSSLPRITSLTEQQLWGAILATAAA
                     TKVDSVVVEIAAEAKEHLSDTAFDAALGAATIMGMNNIFYRTRGFLDGAYDDQRANLRM
                     QIIGKNGGIDKLDFEMLALAVSAVNGCSHCVAAHEHTIREEGASKEQVNDLIRIAATLG
                     GVAQGIQLAEALG"
     gene            complement(1123..1704)
                     /locus_tag="EL250_RS01215"
                     /old_locus_tag="NCTC10207_00246"
     CDS             complement(1123..1704)
                     /EC_number="1.11.1.-"
                     /GO_function="GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888515.1"
                     /locus_tag="EL250_RS01215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00246"
                     /product="peroxiredoxin"
                     /protein_id="WP_023133587.1"
                     /transl_table=11
                     /translation="MAVLSIGDQFPAYELTGVVPGKLAEIEANKPEDYFTTVSSEGLDE
                     DTWRVVFFWPKDFTFVCPTEIAAFGKLADEFEARDCQVIGVSVDNEYTHYAWRRSHEEL
                     VDLPIVMASDLKRELTSALGILNKDGVADRATFIIDPHNTIQSVSITADSVGRNTDEVL
                     RQLDALQSDELCACNWKKGAETIDAFKEMK"
     gene            1891..2475
                     /locus_tag="EL250_RS01220"
                     /old_locus_tag="NCTC10207_00247"
     CDS             1891..2475
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004006489.1"
                     /locus_tag="EL250_RS01220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00247"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_037232989.1"
                     /transl_table=11
                     /translation="MKIPELITEKFTLRPLREADLDELVQICTDPETVRWTTVPLNYTR
                     DDAQTFLTFTQRAAAAGRELTWAIDDSGVLAGAISLRLPEGSANAPGTYADLGFYTAAQ
                     MRGRGIMTDAVRTVLGFGFDPLGLGLDTIGWAALVGNAASERVAVKAGFTNITDGTSTS
                     AARPDKYGNRKAVAVRQATMTRAQFAEIWRD"
     gene            complement(2531..2848)
                     /locus_tag="EL250_RS01225"
                     /old_locus_tag="NCTC10207_00248"
     CDS             complement(2531..2848)
                     /EC_number="3.6.1.7"
                     /GO_function="GO:0003998 - acylphosphatase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005509193.1"
                     /locus_tag="EL250_RS01225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00248"
                     /product="acylphosphatase"
                     /protein_id="WP_126499509.1"
                     /transl_table=11
                     /translation="MGFFSYFTDKTAPEPAEAQLTAYVSGRVQGVGFRWWCAGTAKPMG
                     LSGYAENLDDGRVKVIAQGTRTSCERLLDALNSGDTAGHVDFVDATFSEPQGAFKGFGI
                     R"
     gene            complement(2957..3649)
                     /locus_tag="EL250_RS01230"
                     /old_locus_tag="NCTC10207_00249"
     CDS             complement(2957..3649)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888543.1"
                     /locus_tag="EL250_RS01230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00249"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_126499510.1"
                     /transl_table=11
                     /translation="MAVVTIIGGHGKVALLAEPLLVERGHTVNALIRRPEQSEDIVTRG
                     ANPVVTDITALSTEEMAKLLTELGTEVLVWSAGAGGVGGPERTYAVDRDAAIRSMDAAR
                     LAGIKRYVMVSYLGAGAGHGIDPDNSFYAYAESKAIADEYLRGSGLDYTILGPGMLTLE
                     EAGGITLGIEPAHTPGAESNTPRATVAQVLAAVLEDPSTVGKALPFIGGPTPIAQALAS
                     APNSNKLR"
     gene            3946..5697
                     /locus_tag="EL250_RS01235"
                     /old_locus_tag="NCTC10207_00250"
     CDS             3946..5697
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888609.1"
                     /locus_tag="EL250_RS01235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00250"
                     /product="MDR family MFS transporter"
                     /protein_id="WP_126499511.1"
                     /transl_table=11
                     /translation="MAEEAAPKKRPHTPSIEHAAEKPWVAMWSLVIGFFMILLDTTIVT
                     VALPHMQHELNASLSAVIWVTSAYLLAYAVPLLITGRLGDRFGQKQMYLLGMVVFTLSS
                     LWCGLSPNVEMLIVARVVQGIGASLMTPQTMSIITLMFPPHKRGVAMSVWGAAAGIASL
                     VGPIAGGLLVDGPGWTWIFFINIPIGVIGTYLAVRNIPHFPSKQHNFDWLGVVLSAIGL
                     FLMVFGIQEGSTYDWGIITESLWGTGIPVSVWGMIIAGIIVFTLFIVWQAVNRKEPLVP
                     LGLFKDRNFSVSNIAIAAMGAHTLTLAFPTTIYFQQVRGMSPTQAALMTAPLALFSGAL
                     SPLVGKRLGTSNPKWYAVSGFALLVVGFIVLRALMTADQSLALLLVPFAILGIGNSMIW
                     GPLAVTATRNLPPRLAGAGSGVYNETRQVASVLGSAGIATFMGGLITEQVTQAMQRMRP
                     AGAGAGGGAMSAPAVSGEGMSGGQVPDFLREPIATAMNDSLILALALAAVGMVACLFFA
                     KPVDKGAWASGQNVSDAPSSENTKNTSTESSSAENPGEASSAEAPKATGESGPEPSDKG
                     AETGSKP"
     gene            complement(5826..7973)
                     /locus_tag="EL250_RS01240"
                     /old_locus_tag="NCTC10207_00252"
     CDS             complement(5826..7973)
                     /NRPS_PKS="Domain: AMP-binding (87-575). E-value: 8.6e-94.
                     Score: 306.3. Matches aSDomain:
                     nrpspksdomains_EL250_RS01240_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888461.1"
                     /locus_tag="EL250_RS01240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00252"
                     /product="AMP-binding protein"
                     /protein_id="WP_126499512.1"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-54, bitscore:
                     181.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLPSPFSFTNPLAPTPNPAHESDEARVAFWEKQAERLSWGKAWD
                     NAHTFQKPQVIGTDAEGIEEYSVPEIKWFEGGKLNVAYNCVDRHVEAGRGDKVALYFEG
                     EPGDREAITYAELQRRIARAANGLLKLGVRKGDRVVIYLPVIPETIIFTLACARIGAIH
                     SLVFGGFSAEALKFRVEDTGAKVLITTDGQNRRGKVVPVKVNADEACSGENNIEHVVVV
                     DRTSAADPVAHAQVPWTAGRDIWYHDLVDDQPDTHEYELHDAEDPLFIIYTSGTTGKPK
                     GLVHTMAGYLVQTAYTHALLYDLLPDYVDDDGVLRPDELSAVNDPAKVESTVHWCTADL
                     AWVTAHTYEIYGPLVNGVTEVIFEGTPNTPHYGRHFEVIERYGVTNYYTAPTLIRSLMG
                     AFPDGPEPGKYDFSTVRLLGSVGESINPQAWKWLRKHVGGGTASFIDTWWQSETGSTIC
                     SPRPHDPAFAPEGTFPEGTPHCTPLPGCATREVPGVSVRVVDEHGDLVEPGKQGFIVVD
                     KIGPSMARTVWGDPQRYLNSYWKHYGTRGWFLAGDGAKVDDEGNVYILGRIDDVINISG
                     HRLSTIEIESALVTHPAVVEAGVCPVEDELTGHQAVAYVTLTDEGRALTEDELKTALTQ
                     HVREHIGPIAKPKDVVAVADIPKTRSGKITRRLLGELYQGHKLGDISSLQNEEALGAIA
                     QVLVETGRVSPDAFAEDQAAA"
     CDS_motif       complement(6219..6281)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EL250_RS01240_0002"
                     /evalue="1.60E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="EL250_RS01240"
                     /protein_end="585"
                     /protein_start="564"
                     /score="14.4"
                     /tool="antismash"
                     /translation="LGRIDDVINISGHRLSTIEIE"
     aSDomain        complement(6249..7712)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EL250_RS01240_AMP-binding.1"
                     /evalue="8.60E-94"
                     /label="EL250_RS01240_AMP-binding.1"
                     /locus_tag="EL250_RS01240"
                     /protein_end="575"
                     /protein_start="87"
                     /score="306.3"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="RHVEAGRGDKVALYFEGEPGDREAITYAELQRRIARAANGLLKLG
                     VRKGDRVVIYLPVIPETIIFTLACARIGAIHSLVFGGFSAEALKFRVEDTGAKVLITTD
                     GQNRRGKVVPVKVNADEACSGENNIEHVVVVDRTSAADPVAHAQVPWTAGRDIWYHDLV
                     DDQPDTHEYELHDAEDPLFIIYTSGTTGKPKGLVHTMAGYLVQTAYTHALLYDLLPDYV
                     DDDGVLRPDELSAVNDPAKVESTVHWCTADLAWVTAHTYEIYGPLVNGVTEVIFEGTPN
                     TPHYGRHFEVIERYGVTNYYTAPTLIRSLMGAFPDGPEPGKYDFSTVRLLGSVGESINP
                     QAWKWLRKHVGGGTASFIDTWWQSETGSTICSPRPHDPAFAPEGTFPEGTPHCTPLPGC
                     ATREVPGVSVRVVDEHGDLVEPGKQGFIVVDKIGPSMARTVWGDPQRYLNSYWKHYGTR
                     GWFLAGDGAKVDDEGNVYILGRIDDVINIS"
     CDS_motif       complement(7116..7169)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EL250_RS01240_0001"
                     /evalue="5.70E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="EL250_RS01240"
                     /protein_end="286"
                     /protein_start="268"
                     /score="22.0"
                     /tool="antismash"
                     /translation="FIIYTSGTTGKPKGLVHT"
     regulatory      complement(7979..8095)
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(8228..8243)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            8401..8751
                     /locus_tag="EL250_RS01245"
                     /old_locus_tag="NCTC10207_00253"
     CDS             8401..8751
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888509.1"
                     /locus_tag="EL250_RS01245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00253"
                     /product="VOC family protein"
                     /protein_id="WP_023133590.1"
                     /transl_table=11
                     /translation="MAVKRIVTNLAADKPESAAAFYRDILGLELLMDHGWIQTYGNAET
                     TTVQVSIASEGGSGTPVPDLSVEVDNLDEILARIHAAGIALEYGVAEEPWGVRRFFVRD
                     PLGNLVNILQHM"
     misc_feature    8881..8890
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(8997..9009)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    complement(9169..9183)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.92"
                     /tool="antismash"
     misc_feature    9176..9189
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.27"
                     /tool="antismash"
     misc_feature    9235..9253
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.97"
                     /tool="antismash"
     misc_feature    9604..9617
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(9944..9957)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 18.15"
                     /tool="antismash"
     gene            10001..11623
                     /locus_tag="EL250_RS01250"
                     /old_locus_tag="NCTC10207_00256"
     CDS             10001..11623
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="EL250_RS01250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00256"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_186335903.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.5e-26, bitscore:
                     91.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELYTTSGNVQKISHFLRSSSNNITVRPLPTHEASASNTDSTAD
                     SELVSSVSRHRSVYRSKLGPVDLLSTSVKPLVDALNPAINMSRVALGLCRNPPGWVRRI
                     PYWKNITALPPATTVCEDEHGSVQNTSYFADALSLQDSTLSFSDVSQNVYTVLNSVLRR
                     LAEGRTHVSADLSGGVDSTVISVLLAAQNIPFTAFHAGTDDKDNRDTQLAQKIAEHFTI
                     DLIKLDSFTKSTAGFTIPDELRGFSEAPRAWHANLPHLTALVRSARERGSSIHCLGIGG
                     DELFEPMPVQALLYFKQGEKMRAIKAISSVAAAARWPKVSTLRAAFSPETKQRELQRRL
                     TRRGQNIPENIDAFSWFPNFTLPSWLSEEATEQVIELMRATPIPPEEEELDKYRFHIYG
                     SLEFQGEVLRGMNEYFSETGLEFAAPYLEDDMIRSSLVYPGVLSGHGMSKPVILEAMKG
                     TLPEFFYRDIYKSDYSFDLYQDYERSKENFLKMIGDSLLAELNLVDIDTVRTIANSPLG
                     SSETLYDFERMTHMEVWLRENYV"
     gene            11616..11918
                     /locus_tag="EL250_RS01255"
                     /old_locus_tag="NCTC10207_00257"
     CDS             11616..11918
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="EL250_RS01255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00257"
                     /product="PqqD family protein"
                     /protein_id="WP_037232974.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 8.4e-11,
                     bitscore: 38.9, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1e-07, bitscore: 29.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKRYASLPERFCIADGVKISGTESGIVVFVPARSAYFQGNSTTE
                     HILDLVEQGRRNSEIIDSFIRQYTQSDPDEIREDLEGTLRELWTMGVLEKGEDHG"
     aSDomain        11658..11897
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EL250_RS01255_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.00E-12"
                     /identifier="RREFam002.1"
                     /label="EL250_RS01255"
                     /locus_tag="EL250_RS01255"
                     /protein_end="94"
                     /protein_start="14"
                     /score="38.9"
                     /tool="antismash"
                     /translation="ADGVKISGTESGIVVFVPARSAYFQGNSTTEHILDLVEQGRRNSE
                     IIDSFIRQYTQSDPDEIREDLEGTLRELWTMGVLE"
     gene            11911..12327
                     /locus_tag="EL250_RS01260"
                     /old_locus_tag="NCTC10207_00258"
     CDS             11911..12327
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="EL250_RS01260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00258"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_126499514.1"
                     /sec_met_domain="PF13471 (E-value: 1.5e-18, bitscore: 64.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDNPTTATDAHTVSSIKARLAVCAAKIIAHLPVTVIVRLLKMFR
                     PLQKSSSIQQALAVDAKVREVSPLCRGERGCLARSISTYLLLSLMRRKVVWASGFRVKP
                     FLAHAWVTVEGEPINEHHDVQGFVTVASTNPEAR"
     gene            12488..14152
                     /locus_tag="EL250_RS01265"
                     /old_locus_tag="NCTC10207_00259"
     CDS             12488..14152
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="EL250_RS01265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00259"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_186335904.1"
                     /transl_table=11
                     /translation="MSLTSSAASLLQPLIVNDLVDSAGSAQGIGYLPVLIILVLIIGAI
                     LNGIQQYFIQKVAESVARDARTQLVRKILRIPLDALEKYTKGDILSRVINDTMLLRRCL
                     TEGFVQSFVGIFTLIGAVIGMFFIDPLLLAISAVISLLAVVSVTMATSKVEKSSAQMQQ
                     AVGELSSDVSSVLEASSLVRTENAAGHQFKRLQQKVDNAWLKGIGVARLVALITPISAV
                     AMQITFLVVLGVGGVRVANGIITVGNLVSFVMFLVMMIMPLGYIFGTMSNIAEASGGIT
                     RIQEILGIPDEYPEQLDTYHENRDIRSILLDNVSFKYGAEPEEGASPYLISGMTLSIAP
                     GEKIAIVGPSGSGKSTLLRLIARLYEISGGNLLYSGTASSDISIPAVRAKIGLVQQESP
                     LILGTLLDNVYISGRGTDSAAAHRILKDLGLEKVLERSGHGVDLNIGGSGTSLSGGEKQ
                     RLAIARVILKNPQVYLLDEFTSQLDGISEELVVSVLNNNAAPESTMIMVAHRMSTVVNA
                     DMIYVMDHGRIVAQGTHDILMEFSPLYRELVSNQLIH"
     gene            complement(14168..15028)
                     /locus_tag="EL250_RS01270"
                     /old_locus_tag="NCTC10207_00260"
     CDS             complement(14168..15028)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EL250_RS01270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NCTC10207_00260"
                     /product="transcriptional initiation protein Tat"
                     /protein_id="WP_126499516.1"
                     /transl_table=11
                     /translation="MTHAPFRGGLTRRRALAGAAWSAPAVAASATAPAYAASDQVVAVD
                     YGVFTQAFNTTMDNPNSTFFGLDSYHGQLTDTRASRTTKWEGLLAAGGGTFTPGGSVGN
                     GLYGGAGLWFAAPHTASGEYTGTTTLRAGARFSIEYTFTFADEIQTRPPLLWEDGEQQQ
                     VAALAQSAGGARSNNPRLAAFNGAGFTAVFRESDSYGTEWRGTLDVVTTEDAVASAEGM
                     QVFNQVLLSQVPVYYDQVGESFSLRTTVTVVDATLLLEPVNSAAPSEQNIAGLSASATI
                     THSPA"
     cand_cluster    14907..41905
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    14907..41905
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[24906:31905](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      24907..31905
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="2"
     misc_feature    complement(15004..15020)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.03"
                     /tool="antismash"
     misc_feature    complement(15145..15159)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.39"
                     /tool="antismash"
     CDS             complement(15168..15284)
                     /gene="allorf_0261182_0261298"
                     /locus_tag="allorf_0261182_0261298"
                     /protein_id="allorf_0261182_0261298"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNEIQLIGAPQPPPTRGTRGALRRAPAQECIKIRYVRG"
     CDS_motif       complement(15258..15284)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNEIQLIGA"
                     /locus_tag="allorf_0261182_0261298_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15168..15257)
                     /prepeptide="core"
                     /locus_tag="allorf_0261182_0261298_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.20"
                     /molecular_weight="3209.7"
                     /monoisotopic_mass="3207.8"
                     /core_sequence="PQPPPTRGTRGALRRAPAQECIKIRYVRG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEIQLIGA"
                     /leader_location="[15257:15284](-)"
                     /alternative_weights="3227.7"
     gene            15322..16413
                     /locus_tag="EL250_RS01275"
                     /old_locus_tag="NCTC10207_00261"
     CDS             15322..16413
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888547.1"
                     /locus_tag="EL250_RS01275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00261"
                     /product="hypothetical protein"
                     /protein_id="WP_023133600.1"
                     /transl_table=11
                     /translation="MKSARLFAATVVLIAAGAVPASASTINTYDTDGDGIPNAWEISGY
                     DADGDGTVDVDYPGMGANPYRKDIFVEMDYMPGELATEADLDRITEVFASLPLRNPDGT
                     RGVSIHLDAGPARSAKYNLGGGNEIPHQKLNGMGDWAALKNRHFASARDAGFHYMIWGD
                     YYGNTSSSGLGFTGARGFIVTVGHTYWRGASSDIRVGTFIHELGHNLGLRHGGADEENY
                     KPNYLSIMNYEYQLSGVPRAGGKNYFGYSTHEHMPLDEKNLDERRGLGANAYGYLYKGK
                     PAHRNVDFNKNGVIDAQPVAADVNGNRRMSTLRAKSDMKTLRFAASATSQGVTSTPRTD
                     PYEVEVDYNEVTAEFARERGLLP"
     gene            complement(16513..17445)
                     /locus_tag="EL250_RS01280"
                     /old_locus_tag="NCTC10207_00262"
     CDS             complement(16513..17445)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888349.1"
                     /locus_tag="EL250_RS01280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00262"
                     /product="ABC transporter permease"
                     /protein_id="WP_126499517.1"
                     /transl_table=11
                     /translation="MSVTLDKISDTPELSDTPKHTKSAAAETAAARTAAASTAAGRTQL
                     ASSHRGQPRPKRALPLGAKHYVGLILPAALITLWYVLSTAGVFTAVQLPSPTRVIAAGT
                     ELAQRGELATHLVISTQRVVLGFSIGAVLGLVLGALIGLWGPARIAAAPTIGALRAVPS
                     LAWVPLLLLWIGIGENSKVTLVAIGAFFPVYTTVSAALAHVDPKLVEAARAFGYRGVKL
                     FTTVQLPAVLPSVVSGLRLALAQAWLFLVAAELLGASMGLGYLLTDSQNNGRTDRLLLA
                     IVLLAVLGKLTDALIGVFERWVKAKYPSN"
     gene            complement(17448..18497)
                     /locus_tag="EL250_RS01285"
                     /old_locus_tag="NCTC10207_00263"
     CDS             complement(17448..18497)
                     /GO_component="GO:0009897 - external side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0005488 - binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0042918 - alkanesulfonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888401.1"
                     /locus_tag="EL250_RS01285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00263"
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_126499518.1"
                     /transl_table=11
                     /translation="MTAITRAEALKGLLAFSALTTVLAGCAGEGAGTPGAGAAKGKDTV
                     TVDYATYNPLSLVIKKKGWLEKALQEKGKKLEWVKSAGSNKANEALRSGNIDVGSTAGS
                     AALLARANGSPIKVIDLYSQPEWSALVTTKNSNIHAVSDLKGKSVAVTKGTDPYFLLLQ
                     ALKKEGIAAKEVTIQNLQHADGRTALDNGQVNAWSGLDPIMASAEIESHDVLFYRNLDF
                     NTYGFLNATEQFLTDNPDAAQTIVNVYEYARKWALENTAEATQILADESGIKLETAKLV
                     MERTHLNIDPIPGDKQVQVLKGVGPILVESGDVPNQSDIDKALSSIVDDTYAKKADSAA
                     IENVKKTVS"
     misc_feature    18539..18554
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.87"
                     /tool="antismash"
     gene            complement(18610..19431)
                     /locus_tag="EL250_RS01290"
                     /old_locus_tag="NCTC10207_00264"
     CDS             complement(18610..19431)
                     /EC_number="7.6.2.14"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888518.1"
                     /locus_tag="EL250_RS01290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00264"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_023133603.1"
                     /transl_table=11
                     /translation="MTQNHHTQLPANAQTITFDAVSQSFPQSGKNTHEVLREVSFTAAA
                     GEIISVIGASGCGKSTLLRAAAGLNRITGGQVRIGDTPVSGLDQRVAIGFQEPRLLPWR
                     TVADNVALGLPQGTPKTRAQERIRELLRLVGLTDYATHRPKEISGGMAQRVSLARALAR
                     EPGVLLLDEPFGALDALTRIKMQDLLLDIHRQDPTTILLVTHDVEEALYLSDRVIVLGK
                     SAPDAPATITRVVTISDAHPRDRASKELTALRAELLTELGVEKADTTPVPA"
     regulatory      complement(19436..19517)
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     CDS             19581..19766
                     /gene="allorf_0265595_0265780"
                     /locus_tag="allorf_0265595_0265780"
                     /protein_id="allorf_0265595_0265780"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTKYCMSHAKYYGAESQKLMFVIYCSPPSARGYTQNARIMSPGVK
                     LWLAGRQPSPVAGCPR"
     CDS_motif       19581..19622
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTKYCMSHAKYYGA"
                     /locus_tag="allorf_0265595_0265780_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       19623..19766
                     /prepeptide="core"
                     /locus_tag="allorf_0265595_0265780_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="5041.9"
                     /monoisotopic_mass="5038.6"
                     /core_sequence="ESQKLMFVIYCSPPSARGYTQNARIMSPGVKLWLAGRQPSPVA
                     GCPR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTKYCMSHAKYYGA"
                     /leader_location="[19580:19622](+)"
                     /alternative_weights="5059.9"
                     /alternative_weights="5077.9"
                     /alternative_weights="5095.9"
                     /alternative_weights="5114.0"
     CDS             complement(19613..19681)
                     /gene="allorf_0265627_0265695"
                     /locus_tag="allorf_0265627_0265695"
                     /protein_id="allorf_0265627_0265695"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MYPLADGGEQYMTNINFCDSAP"
     CDS_motif       complement(19646..19681)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MYPLADGGEQYM"
                     /locus_tag="allorf_0265627_0265695_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(19613..19645)
                     /prepeptide="core"
                     /locus_tag="allorf_0265627_0265695_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="1045.1"
                     /monoisotopic_mass="1044.5"
                     /core_sequence="TNINFCDSAP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MYPLADGGEQYM"
                     /leader_location="[19645:19681](-)"
                     /alternative_weights="1063.1"
     CDS             complement(19682..19822)
                     /gene="allorf_0265696_0265836"
                     /locus_tag="allorf_0265696_0265836"
                     /protein_id="allorf_0265696_0265836"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MCRWRIRAVLASCSLKPDHHLGHPATGEGCRPASQSFTPGLIILA
                     F"
     CDS_motif       complement(19787..19822)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MCRWRIRAVLAS"
                     /locus_tag="allorf_0265696_0265836_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(19682..19786)
                     /prepeptide="core"
                     /locus_tag="allorf_0265696_0265836_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="3468.9"
                     /monoisotopic_mass="3466.8"
                     /core_sequence="CSLKPDHHLGHPATGEGCRPASQSFTPGLIILAF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MCRWRIRAVLAS"
                     /leader_location="[19786:19822](-)"
                     /alternative_weights="3487.0"
                     /alternative_weights="3505.0"
                     /alternative_weights="3523.0"
     regulatory      19694..19803
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00634"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00634"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="SAM riboswitch class IV; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     CDS             complement(19777..19881)
                     /gene="allorf_0265791_0265895"
                     /locus_tag="allorf_0265791_0265895"
                     /protein_id="allorf_0265791_0265895"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MFLHPARRLLIGGGLLGVPSCAGGAFAPYLLRVP"
     CDS_motif       complement(19843..19881)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MFLHPARRLLIGG"
                     /locus_tag="allorf_0265791_0265895_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(19777..19842)
                     /prepeptide="core"
                     /locus_tag="allorf_0265791_0265895_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="2040.4"
                     /monoisotopic_mass="2039.1"
                     /core_sequence="GLLGVPSCAGGAFAPYLLRVP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MFLHPARRLLIGG"
                     /leader_location="[19842:19881](-)"
     gene            19908..21335
                     /locus_tag="EL250_RS01295"
                     /old_locus_tag="NCTC10207_00266"
     CDS             19908..21335
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004006498.1"
                     /locus_tag="EL250_RS01295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00266"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_004006498.1"
                     /transl_table=11
                     /translation="MAEQKKRIAVNAFDMTCVGHQSFDLWRHPRSRATEYNTIKYWTDL
                     AQILEKGFFDGVFLADVVGIYDIYKNSAAPAIEGGAQVPVNDPFMQISAMAAVTEHLGF
                     GVTSAVTYEQPYTLARKYASLDHLTNGRVGFNVVTSYLPSAAECQGLETQIEHDTRYEL
                     AEEFLDVCYKLWEGSWEDGAVVKDREKGIYADPAKVHPIQHKGKYFSVPGAGLTEPSPQ
                     RTPVIFQAGASSRGQKFSGKHAEVVFIGALRPDLTRIITDRIRDRAEENGRGRDEIKVF
                     AMLSIIVDETEEKAKAKYEEYRKYVNLESSQAIIGGWSGVDLSQFDEDEVLNYVKTESI
                     QSFLTPFTLQAKDKQWTRKDIAEHCTIGGMGEVIVGDPQQVADELERWIDEGGLDGINL
                     AYHVSPGSFEDFIEFVVPELQKRGRYRTSYEGETLRESLFGKGQTKVADSHPAAKYRGA
                     YVGKPSTADTPARAIAN"
     gene            21463..21909
                     /locus_tag="EL250_RS01300"
                     /old_locus_tag="NCTC10207_00267"
     CDS             21463..21909
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888376.1"
                     /locus_tag="EL250_RS01300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00267"
                     /product="YchJ family protein"
                     /protein_id="WP_126500813.1"
                     /transl_table=11
                     /translation="MGCMSETTLYDLQTRCLCTSGEVYGACCGRYLGEFAASGILNAPT
                     PLALMRSRFTAFALHDAPYLLASWHPHTRPAELDTDETLRWYRLDILGSSSGPFDAAGT
                     VEFVAYYRSVPGTPAEERVKGTMHEKSRFKKVNGTWYYLDGEVS"
     gene            21930..22607
                     /locus_tag="EL250_RS01305"
                     /old_locus_tag="NCTC10207_00268"
     CDS             21930..22607
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013398387.1"
                     /locus_tag="EL250_RS01305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00268"
                     /product="hypothetical protein"
                     /protein_id="WP_126499519.1"
                     /transl_table=11
                     /translation="MAKTFLLWYVFAMMSVAEYAQHAGVSPRSVRARLERGSLRGQKIA
                     GRWMVSDNPHEHYSAHGRKISMASFNQLAAYLDGNSASLTPDARRRAKERAHNISERGV
                     EALRQYAVRADAKPQFYAVPSADLHDLMGERALVLTGVSHEYSEIYGATVDAYVTPRDL
                     ESLKFIYALREVHAQDANVILRVIKELPKIRPLHVAVDLLISKDPRSEREAERLVKGLI
                     SRA"
     gene            22717..23343
                     /locus_tag="EL250_RS01310"
                     /old_locus_tag="NCTC10207_00269"
     CDS             22717..23343
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005507247.1"
                     /locus_tag="EL250_RS01310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00269"
                     /product="hypothetical protein"
                     /protein_id="WP_232018597.1"
                     /transl_table=11
                     /translation="MMRLLACERGYEGSRATRDIDVVLNIRARRRLIGEFVHALKSTGF
                     VIDGYNVSGQNHRWVRGLAQIDVLVPSGQSEKTLSYDFSGLGKVLMTRGAQFGIDRTSS
                     VAVECAGRTFLVNRPDALGALYEKCSALLNNGDTHKQRHFHDILVLVCLLSTSERRDLI
                     GLSGKQRSRLAWGLRRALAEPGIGRPHEREMAQNIVSFLNESLKN"
     gene            23368..23880
                     /locus_tag="EL250_RS01315"
                     /old_locus_tag="NCTC10207_00270"
     CDS             23368..23880
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888379.1"
                     /locus_tag="EL250_RS01315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00270"
                     /product="hypothetical protein"
                     /protein_id="WP_126499521.1"
                     /transl_table=11
                     /translation="MSDVISQESFNMLALYFNGGGHLLTPDARHSAAERARILCAHGLD
                     ALRQYTHRTGMTVHYYVAPYDTSDLLRTGADALALTGARHELSRIKTSLIDAYILPDDL
                     TKFAPSWGLEPAPSERANVILREVSTLPRVLRLHVAADALHAYEAGAAGESARKAAQRI
                     LGELCSS"
     CDS             23982..24197
                     /gene="allorf_0269996_0270211"
                     /locus_tag="allorf_0269996_0270211"
                     /protein_id="allorf_0269996_0270211"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MEIMMRTYCILPRWFDTVEGLARVAISLLQGRELIVGVLLRMQRM
                     DSIESFRKLILGSYCVIGTVLHSHIS"
     CDS_motif       23982..24155
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MEIMMRTYCILPRWFDTVEGLARVAISLLQGRELIVGVLLRMQRMDSIESFRKLILGS"
                     /locus_tag="allorf_0269996_0270211_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       24156..24197
                     /prepeptide="core"
                     /locus_tag="allorf_0269996_0270211_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.70"
                     /molecular_weight="1374.6"
                     /monoisotopic_mass="1373.7"
                     /core_sequence="YCVIGTVLHSHIS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEIMMRTYCILPRWFDTVEGLARVAISLLQGRELIVGVLLR
                     MQRMDSIESFRKLILGS"
                     /leader_location="[23981:24155](+)"
                     /alternative_weights="1392.6"
                     /alternative_weights="1410.6"
     misc_feature    24055..24071
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.75"
                     /tool="antismash"
     CDS             complement(24082..24267)
                     /gene="allorf_0270096_0270281"
                     /locus_tag="allorf_0270096_0270281"
                     /protein_id="allorf_0270096_0270281"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLCALIALYYGHHITKWCDIKWKLRICESVKLFLSHNRSPISAFG
                     SSQCYPFFASSIEHPQ"
     CDS_motif       complement(24235..24267)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLCALIALYYG"
                     /locus_tag="allorf_0270096_0270281_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(24082..24234)
                     /prepeptide="core"
                     /locus_tag="allorf_0270096_0270281_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="5699.5"
                     /monoisotopic_mass="5695.9"
                     /core_sequence="HHITKWCDIKWKLRICESVKLFLSHNRSPISAFGSSQCYPFFA
                     SSIEHPQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLCALIALYYG"
                     /leader_location="[24234:24267](-)"
                     /alternative_weights="5717.5"
                     /alternative_weights="5735.6"
                     /alternative_weights="5753.6"
                     /alternative_weights="5771.6"
                     /alternative_weights="5789.6"
                     /alternative_weights="5807.6"
     CDS             complement(24396..24467)
                     /gene="allorf_0270410_0270481"
                     /locus_tag="allorf_0270410_0270481"
                     /protein_id="allorf_0270410_0270481"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVENRDLASSSPKHSTIKNCSRK"
     CDS_motif       complement(24438..24467)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVENRDLASS"
                     /locus_tag="allorf_0270410_0270481_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(24396..24437)
                     /prepeptide="core"
                     /locus_tag="allorf_0270410_0270481_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="1413.6"
                     /monoisotopic_mass="1412.8"
                     /core_sequence="SPKHSTIKNCSRK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVENRDLASS"
                     /leader_location="[24437:24467](-)"
                     /alternative_weights="1431.7"
                     /alternative_weights="1449.7"
                     /alternative_weights="1467.7"
     gene            24665..24877
                     /locus_tag="EL250_RS01320"
                     /old_locus_tag="NCTC10207_00271"
     CDS             24665..24877
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004006420.1"
                     /locus_tag="EL250_RS01320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00271"
                     /product="bacteriocin"
                     /protein_id="WP_126499522.1"
                     /transl_table=11
                     /translation="MAKDTMFMEELTDQELEQVNGGCYSSCGYYGGSYGGSYGGSYGGS
                     SSSYYGGSYSGGGYYYAAVGYGYSC"
     CDS_motif       24665..24730
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAKDTMFMEELTDQELEQVNGG"
                     /locus_tag="EL250_RS01320_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       24731..24877
                     /prepeptide="core"
                     /locus_tag="EL250_RS01320_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="4.70"
                     /molecular_weight="4594.7"
                     /monoisotopic_mass="4591.8"
                     /core_sequence="CYSSCGYYGGSYGGSYGGSYGGSSSSYYGGSYSGGGYYYAAVG
                     YGYSC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKDTMFMEELTDQELEQVNGG"
                     /leader_location="[24664:24730](+)"
                     /alternative_weights="4612.7"
                     /alternative_weights="4630.7"
                     /alternative_weights="4648.7"
                     /alternative_weights="4666.7"
                     /alternative_weights="4684.8"
                     /alternative_weights="4702.8"
                     /alternative_weights="4720.8"
                     /alternative_weights="4738.8"
                     /alternative_weights="4756.8"
     misc_feature    complement(24878..24887)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.08"
                     /tool="antismash"
     gene            24907..27915
                     /gene="lanM"
                     /locus_tag="EL250_RS01325"
                     /old_locus_tag="NCTC10207_00272"
     CDS             24907..27915
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018081 - peptide cross-linking via
                     lanthionine or 3-methyl-lanthionine [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888544.1"
                     /locus_tag="EL250_RS01325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00272"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_126499523.1"
                     /sec_met_domain="DUF4135 (E-value: 2.4e-63, bitscore:
                     211.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5e-34, bitscore:
                     114.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIRELLPELDNEQFQQLVSDVSDVSLLDRLDTTSDSPPVGRPSA
                     PVPSALGPTAEPAMFYTLFAWLFESEYKRVVQAVRASHYIEREHFPNIVGGLLDEFTVR
                     LANFYIRPLVAHIKKVSSEGLLQGDTPEERYIDYCRRWPKDFMDGFYTSYPLLRRVHSI
                     IVHQFHAIVAELFERIQAQESGIRELLGAQNAESLTLESLTMAGDYHNGGRTGCLLVFS
                     QGTVAYKPRSVDGERAFYRIVQKLAEQGAPRMRAARVVQGEDYGFMEFIEREDVDFTAE
                     KFLESSGQLSALFYALLGKDMHEENLIPTSEGAVPIDLETILHCSHLLNDGKADMPDNS
                     ALLHKERGICTSALLPTRLVRKDPSKGYVDIGFIRGEQGANPFKGTVIEQPFRDDAIVR
                     SVRYSDLGGPQQGNDPDTHTLEKRRATEVARARGFVRGFEQMYRWVCEHRDAMLELVRS
                     ECAALTLRAVLQPTMQYEQLVRMLGSPEALSSKSVFATVALRTAAFDDDRSLELVLAEV
                     ESLWQLDIPFFKHRADRTAIMTPDGQEVGLGIKTSALEETLNHISHMGEDDLDEQLNQI
                     WSAFISPYPANTLADEPADIRQGRGGEREERELSTMIADRLVATVHPGTAPEDPWTWVS
                     PVPSSQQHHHGIWNTDVLQTDLYGGSVGIALALAQAAHVLGHQEYAETAHRVFDPLAET
                     ILSGEKPLKLPEYIRDMAFAGEPGIAFALAGAARYLGDTRLKDAALELGNQVAARIAKV
                     EHPTPGYLSGHVGAATLLLGHELATDRQALLAVLDRHAQDIIAGRIDDAWWAQSGFATG
                     MSSSIFALSRWSQDMPSPERARQAVAFLLNRLDELDNGEYWQMRVPIGESAHDGTWCHG
                     SAGVALALAAVHCWLPELSNRASLDRAVRRSLQEGTKRNFTSCHGALGTLDVLEWVVSH
                     VPDVSTAEAVHNAVKNGYNVSLLRETLNDKSVRYSLTPSLMVGTSGVLSWLTRRAGDTH
                     LYTPIVPDSAEAH"
     misc_feature    complement(28238..28254)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 24.59"
                     /tool="antismash"
     misc_feature    28247..28265
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 21.44"
                     /tool="antismash"
     misc_feature    28411..28427
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.72"
                     /tool="antismash"
     gene            28616..28804
                     /locus_tag="EL250_RS01330"
                     /old_locus_tag="NCTC10207_00273"
     CDS             28616..28804
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EL250_RS01330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NCTC10207_00273"
                     /product="hypothetical protein"
                     /protein_id="WP_006888468.1"
                     /transl_table=11
                     /translation="MPKDITLLEEISDQELGQVNGGGSHGGGYYSSVGGGSYGGGYCGG
                     GCGGYGYGFGFWGGSFS"
     CDS_motif       28616..28681
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPKDITLLEEISDQELGQVNGG"
                     /locus_tag="EL250_RS01330_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       28682..28804
                     /prepeptide="core"
                     /locus_tag="EL250_RS01330_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.20"
                     /molecular_weight="3622.7"
                     /monoisotopic_mass="3620.4"
                     /core_sequence="GSHGGGYYSSVGGGSYGGGYCGGGCGGYGYGFGFWGGSFS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPKDITLLEEISDQELGQVNGG"
                     /leader_location="[28615:28681](+)"
                     /alternative_weights="3640.7"
                     /alternative_weights="3658.8"
                     /alternative_weights="3676.8"
                     /alternative_weights="3694.8"
     gene            28846..31905
                     /gene="lanM"
                     /locus_tag="EL250_RS01335"
                     /old_locus_tag="NCTC10207_00274"
     CDS             28846..31905
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018081 - peptide cross-linking via
                     lanthionine or 3-methyl-lanthionine [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888423.1"
                     /locus_tag="EL250_RS01335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00274"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_126499524.1"
                     /sec_met_domain="DUF4135 (E-value: 1.6e-53, bitscore:
                     179.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.6e-29, bitscore:
                     98.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIRELLPELDEEQFQRLASYVSSTSLLERIGTTASEAPDSDFIV
                     RLSAPVSSALGPTAEPSMFHALIAQLAENERGNVEHAITSSGYAVTSQIPRLTNQFLDN
                     LTARLNNFYLRPLVAHIKKASAQGLLQADTPEGRYEDYCRRWHEELSDDFHASYPLLNR
                     IHQVTVQQFHAMIAEIFERVRTHENDIRELLNTTDAAPLQLESFGLPRTRYGGGRAGCL
                     LKFTQGTVVYKSRNVEGERAFWQIVQDLTQQGAPTMRAARVVQGEGYGFMEFIKAEEVD
                     FSGEDFLEASGRLAGLLYALQGKDMHAKNLIPLATGPVPIDLETVLHPIYILADDTPQP
                     PEGSAHLRKLRGISNSAFLPTRITRRDASLGYRDVGFLHGEQGNDPFNEVIVERPFRDD
                     AAARMNREPAPAPEENQEAASMVALVGDESSVEVLEERRLYEAARARAFARGFTQMHQW
                     ICEHREAMLEAVRANFTGLMLRALLQSTRFYTQILKMLSSPEALASQEVFATVGLRAAT
                     LSHNRPLDMVAAEAEALWRFDVPFFMHQTDGSDIVSFEGKPVGLSIKGSALEETLRHIA
                     ALDENDLEEQLQQIWAAFISPYPANTLANSPAELLSAGEDEQHEQELCAAIADQLTGTL
                     RLGGSEQDSRTWLAPNPGLWQQHIGAWQTTVLGIDLYTGSVGPAMALAQAAHTLGNAEY
                     AQAAHRVLDPIAQDVFDKRLFSIPPETCDGVSGGEAGIALSLASAAEYLDDPRLKEAAI
                     MLGDRVAARMEQVEHPMPGYLDNQVGAATLLLGYNLATNRAALLEVLEKHALDIVAGRV
                     EENWWNVSGFAYGVSGSIFALARWGQEMPTPGRAQHAVKILLQRLNSFRYPEGWRAQLS
                     ERSGTGDAHTGGTWCSGSAGIALALAAVHVWMPEFSPRTELDRAVQYAFRTGTRSNLTL
                     CHGDLGTLEVLNWIIARVPDVPGAEDIRAAVKNGYGPSVIRATLDDKSSRYSLTPSLLV
                     GTSGVLSWLAHRLGGGRLYTPVIPDVSEDR"
     gene            31909..34284
                     /locus_tag="EL250_RS01340"
                     /old_locus_tag="NCTC10207_00275"
     CDS             31909..34284
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888614.1"
                     /locus_tag="EL250_RS01340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00275"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_094758609.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1e-26, bitscore:
                     90.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFPAVLQAAATECGLGVGASVLQHYGRYQTISDLRLIAEPGREG
                     LSMLQVRNLLMAEGMDVGAYKANSLEQLRDIGKPAILHWNNSHYVVLVRIRKDRVHIMD
                     PATGMKVIPLQEAEGSFSGSVLVPTPRKDFKKKSRKVFQDWQLNTFFTKKMFAQYAVFV
                     VLLVITYSVTFAVPVVIQSVVDAQLRGHEDAILVATIGVVVGVAGYYLVSIARAAALAS
                     IVSSIGYQLLGGMFKRLLKLPLTYFALRSPGDILYRLSSVNTLRNFLSTNLTELVINIG
                     TMIVILVFIAQQSREILIITFVVLAVLMLIWFVTARPTSQALDAEYAHASEAQVVELDA
                     INTVASMKMTGSASSTYETWREAYKQSLASMRRRMVLQQGVLGSAASVVQLGGPLILLL
                     ASLPLVNQGVLTLGQAIATEGISAMLFSSISSTMFGIMNIIAVDRAVARIVDIQRYDPE
                     QDGGTITKLASSDIELENVNFTYPGGTQPVLSEVSITVPEGHDIALVGSSGSGKSTLAM
                     LLCSLYSPVSGTIRMGGINVQDYSLDALRSHIGYVPQQLQTRGGTLYENLTAGLDDGRT
                     REEIEADVLSMGILDFVKGLPMGFDTIMSSDGENFSGGQRQRIAIVTALLRRPRILVLD
                     EATSALDTTTERQVTELIARYKCTKVVVAHRLSTIRNAQRIIVLEGGRIIQSGSHDELI
                     RVPGRYRDLYYLEDPESIAQEIRAHEAPQTQGKPQAQEPQDEQREYEESLYDHMAWVGV
                     ESAPRFRCRTSFWSSGSRYREATAARMHKAADNSRWLG"
     gene            34567..34968
                     /locus_tag="EL250_RS01345"
                     /old_locus_tag="NCTC10207_00276"
     CDS             34567..34968
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888519.1"
                     /locus_tag="EL250_RS01345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00276"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_232018598.1"
                     /transl_table=11
                     /translation="MSIVYAQKDVRVSRIVDFVESVEQRIKCENGSTDIMVNASDIFYC
                     ESVKKTTFVHVAGNTYRTDHRLYDLAEKLKDCGFVRVSKSCILNINVLESVKPLFNSRM
                     EAILTTGDRVYINRTYLKNVKQALKGYGA"
     gene            34965..35357
                     /locus_tag="EL250_RS01350"
                     /old_locus_tag="NCTC10207_00277"
     CDS             34965..35357
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EL250_RS01350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NCTC10207_00277"
                     /product="hypothetical protein"
                     /protein_id="WP_126499526.1"
                     /transl_table=11
                     /translation="MRKLAVNICATTGISLILLAVIGLLSGGTYLYLVGVFQVLTTNMM
                     IHVGMLLVSRMALKYPLLEALVDIALILVMICGSGLAFGWFSSTPLWILCILGIVMYGA
                     STALNILHMRREVQEINMLIVRRKFT"
     gene            35441..36322
                     /locus_tag="EL250_RS01355"
                     /old_locus_tag="NCTC10207_00278"
     CDS             35441..36322
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888449.1"
                     /locus_tag="EL250_RS01355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00278"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_126499527.1"
                     /sec_met_domain="Abi (E-value: 3.3e-15, bitscore: 53.4,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLEKINVLYCVLAVYCVCFIFRIYEYFVLRTDQSFWGEAFVHKL
                     IGIGILGLVMQSCSLGARSIGFTREHIMRPILAGLGFGAVVFAIAYAAEIALLPPTEFR
                     SLDVYVSTYAVSSNTGHQTALIFFVICLAGNMINVVMEEGVFRGLFQKLLGFRYSFMGA
                     AVISSALFGLWHVIAPVRNYTDGTSSLGGAVMNALILMLTSAVVGFKFALMTRLTGSLY
                     MAMANHCANNVIVNLVHVTSVSGEDTLMFVRISIAQGLSFLVVAVWYLVASRRGSLPAA
                     GIEVAPASHPQP"
     gene            complement(36463..37932)
                     /locus_tag="EL250_RS01360"
                     /old_locus_tag="NCTC10207_00279"
     CDS             complement(36463..37932)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005507244.1"
                     /locus_tag="EL250_RS01360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00279"
                     /product="NCS2 family permease"
                     /protein_id="WP_126499528.1"
                     /transl_table=11
                     /translation="MSSENTAAPQAHKPNASGGALDRYFKITERGSSISAEIRGGLAAF
                     FAMSYIVVLNPLVIGTGADSAGNTLGVPQVAAVTALVAGVMTILMGVIAKQPFAMAAGL
                     GVNALLASTIATTPGLTWADIMGLVIIAGLIMTVLVLTGFRTAVFEAVPESLKTAIVAG
                     IGFFIAFIGLVDSGIIRRMPDAAGTTVPVSLGVGGHLLGWPTLVFIFGLFLTIALFIRN
                     VRGAILIGVVASTVLAIILEAVFHIGSSKGNPTGWSLNVPALNNFSFSAPDFSLIGSAR
                     FGAFGAIGVLGASLLVFAILLSVFFDAMGVSVGLATEAGTIDKDGKVENINEVLLVDAV
                     GSVVGGGASGSANQIFVESATGIGEGARTGLANIVTGVLFLVAIIASPLVTIVPFEAVA
                     PALVVVGFLMVRQAVHIDWQDWGLGIPAFMTIIFMPLSYSIANGIGAGFVSYAFIRLVQ
                     GRGREVHWLMYVVSAVFVIYFGMGIINGFTH"
     gene            complement(38143..39615)
                     /locus_tag="EL250_RS01365"
                     /old_locus_tag="NCTC10207_00280"
     CDS             complement(38143..39615)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006888587.1"
                     /locus_tag="EL250_RS01365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00280"
                     /product="NCS2 family permease"
                     /protein_id="WP_126499529.1"
                     /transl_table=11
                     /translation="MSSENTAAPQAPQTRTTQGALDRYFKITERGSTISAEIRGGLATF
                     FAMSYIVVLNPLIIGLVKDANGHALGVPQVAAVTALIAGIMTIAMGIYAKQPFAMAAGL
                     GVNALLATTILSTPNLTWPQIMGLVVWAGVLMTALVLTGFRTAVFEAVPESLKTAIVVG
                     IGFFIAFIGLVNAGIIRRTVDAAHTTVPVTFGVGGHLLGWPTVVFLVGLFLTIALFIRK
                     VRGAILYGVLASTVLSIILEAVFHIGSSKDNPTGWSLNVPAWGGGSALPDVSLLFSADM
                     FGAFGTIGGMAATMLVFTILISAFFDAMGTTVGLATEAGTIDKDGKIENIDRVLLVDAL
                     GSVAGGGTSSSANQIFVESATGIGAGARTGLANVVTGALFVGAVFLSPLVTIVPFEAVA
                     PAMVFVGFLMIRQAVHIDWQDWGLGIPAFMTIIFMPFAYSIADGIGAGFISYVFIRLVQ
                     GRGREVHWLMYVVSAVFLVFFSTGLINGFTHG"
     misc_feature    39812..39827
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.84"
                     /tool="antismash"
     gene            39924..40259
                     /locus_tag="EL250_RS01370"
                     /old_locus_tag="NCTC10207_00281"
     CDS             39924..40259
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005507240.1"
                     /locus_tag="EL250_RS01370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00281"
                     /product="DUF2218 domain-containing protein"
                     /protein_id="WP_006888504.1"
                     /transl_table=11
                     /translation="MSEYPPAESLPVRQRAVVATERPARYVKQLGSHMGRKIDTAELPG
                     GLRLTFNRDGIFRGYGDLLIDEANNALIMEVRAEDEEKATNIAGVLDRHLVRFGERDEL
                     VVEFRRV"
     gene            40329..40628
                     /locus_tag="EL250_RS01375"
                     /old_locus_tag="NCTC10207_00282"
     CDS             40329..40628
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018925.4"
                     /locus_tag="EL250_RS01375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC10207_00282"
                     /product="DUF1440 domain-containing protein"
                     /protein_id="WP_023133614.1"
                     /transl_table=11
                     /translation="MHFAFAIFFAVLYCVVAEYWPKIKLWQGVAFGIVLDILFHVIIMP
                     AMGVVPAPWNQPFGEHFSEFFGHILWLWSIELVRRDLRNRITGEPDAEYPVTAR"
     misc_feature    complement(40984..40998)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 20.1"
                     /tool="antismash"
ORIGIN
        1 tggcgtgcgc cagcttctaa aacacatact tcgcgagggt cacgcatccg ttatcctgca
       61 ccggagtgaa gccgaaacgc tggtagagtt caatgacggg tgtgtccaca atatccgtag
      121 tgatgaacct ctggcgaatg ccttcccggt caaaatcggc gatgattttt cccagcagcg
      181 ccgacccgat gccgtggcgc tgagcctgcg ggtgcaccag tagatcctgg acatacgcaa
      241 tggtttgtcc atcacctacc gcacgtacca gaccgataag ccgctcggtc ccttcagccg
      301 tgttctcacg cgccacatag aggtaccgcg acccagctag catagggact aatcgctctg
      361 gtgtgcgagt gtagacactc cagcccaccg catcgtacag ttcaacgagc tcttcggtgc
      421 tcggcaggga attctcggcg ttcaaaatac tgtactgcat acccacatta tcctacgccc
      481 gcgcactaaa aggctcttct cccattagct tgcgtcaaag acgccggttg gttcgggaga
      541 agagcctttt agacgagatg tctgcgctgt gaggccaacg gggcctgtgt gtttagccca
      601 gtgcttcagc cagctggata ccctgcgcca cgccgcccaa agttgccgca atgcggatca
      661 ggtcattaac ctgctccttg gaagcaccct cctcgcggat ggtgtgctcg tgggcagcca
      721 cgcagtgcga acaaccgttc acggcagaaa ctgcgagcgc cagcatctca aagtcgagct
      781 tgtcgatacc gccgtttttg ccaatgatct gcatgcgcag gtttgcgcgc tgatcgtcgt
      841 aggcgccgtc gaggaagcct cgggtgcggt agaagatgtt gttcatcccc atgatggttg
      901 ccgcgccgag tgccgcatcg aaggcggtgt cgctcaggtg ctctttcgcc tctgctgcga
      961 tctcaacgac aacggaatca accttggttg ccgctgcggt ggccaggatt gcgccccaga
     1021 gctgctgctc ggtgagcgag gtgatgcgcg gcagcgaaga caggttcagg ttcatgtcct
     1081 tcgcgtagga aggcagcgcg ttacgcaggt tctcgatgct cattacttca tctccttgaa
     1141 ggcgtcgatg gtttctgcac ccttcttcca gttgcaggcg cacagttcgt cggactggag
     1201 cgcatccagc tggcggagca cttcgtcggt gttgcggccg acggaatctg cggtaatgga
     1261 caccgactgg atggtgttgt gcgggtcgat gatgaaggtt gcgcggtctg ccacgccgtc
     1321 cttgttgagg atgcccaggg cgctggtgag ctcgcgcttg aggtcggatg ccatgacgat
     1381 gggcagatct acgagctctt cgtgggagcg gcgccatgcg tagtgggtgt attcgttatc
     1441 cacggatacg ccgataacct ggcagtcgcg tgcctcgaat tcgtcggcga gcttgccgaa
     1501 tgcggcgatt tcggtggggc agacgaaggt gaagtccttg ggccagaaga atacgacgcg
     1561 ccaggtgtct tcgtccaggc cctcggagga aacggtggtg aagtaatctt cgggcttgtt
     1621 tgcctcaatc tcggcgagct tgccgggaac aacgccggtc agctcgtagg cggggaactg
     1681 gtcgccaatg gatagtacag ccatttatgc cctttcaggt tgtggtgtga agctcccgaa
     1741 cgatagtgtg cggtctttcg gaaactgtat ttttggtgcc ctcgaagggg aagtaactcc
     1801 atattattat gagtaattca taattacaag gtggcgaggg cctctgagta tgtgttttgt
     1861 atcactctat ggcgtgtgta tactcgtgcc atgaaaattc ctgaactcat caccgaaaaa
     1921 ttcaccctca ggcccctgcg tgaagctgac ctcgacgaac tggtgcagat ctgcaccgac
     1981 cccgaaaccg tgcgctggac caccgtcccc ctgaactaca cgcgcgacga cgcgcaaacc
     2041 tttctcacct tcacccagcg cgccgcagcc gccgggcgtg aactcacctg ggccattgat
     2101 gacagcgggg tgctcgcggg ggctatctcc ctgcgcctgc ccgaaggctc cgcaaacgca
     2161 ccgggaacat atgcagactt agggttttat acggctgccc agatgcgcgg acgcggcatt
     2221 atgaccgatg cggtacgcac cgtcctcggc ttcggcttcg acccgctcgg gctgggacta
     2281 gacactatcg gatgggcagc actagtggga aacgcggcat ccgaacgggt ggcggtaaaa
     2341 gccgggttta cgaatattac cgacggaacc agcaccagcg cggcccgccc cgataagtac
     2401 ggcaaccgga aggctgtcgc cgtgcggcag gcaaccatga cccgcgccca attcgctgaa
     2461 atctggcgtg attaaggcat ttagtgtgtg tatcctggct tctcgctttt tagcatgggg
     2521 agtgggggcg ctaccggatc ccgaaccctt taaaagcccc ctgcggttcg ctgaaggtgg
     2581 catccacaaa gtccacatgc ccagcggtat cacccgagtt gagcgcatcc agcaggcgct
     2641 cgcaggaggt gcgggttccc tgcgcgataa ccttcacacg gccatcgtcc aggttctcgg
     2701 cgtacccgct caaacccatc ggtttggcgg tgccagcgca ccaccagcgg aaccccaccc
     2761 cctgcacccg cccgctcacg tacgcggtga gctgcgcctc ggcaggttcg ggcgcggttt
     2821 tatcggtgaa atagctgaag aagcccatac ggacgcccct ttaccggtca ttactcgtgc
     2881 tcatagccat tatctaaaac tgcggcccgg attgcacgaa tccgggccgc cacctgccac
     2941 acatgcaggg actgtactag cgcagcttat tgctgttggg cgccgacgcg agagcctgag
     3001 cgatcggggt gggcccgcca ataaacggga gcgccttccc aaccgtggac gggtcctcaa
     3061 gaaccgccgc cagcacctgg gcaacggtgg cccgcggagt attagattcg gcgccgggcg
     3121 tgtgggcggg ctcaatcccc agggtaatgc cgcctgcctc ctcaagggtg agcatccccg
     3181 gccccaggat cgtgtaatcc agccccgagc cgcgcaggta ctcatcggcg atcgctttcg
     3241 actcggcgta ggcgtaaaaa ctgttatcag ggtcgatgcc gtgcccggca cccgcaccca
     3301 ggtacgatac catcacgtac cgtttaatac cggccagccg cgccgcatcc atcgaccgga
     3361 tcgcggcgtc acggtcaacc gcgtaggtgc gttccggccc gccgacgccg cccgcaccgg
     3421 cagaccacac cagcacctcg gttcccagct cagtcaaaag cttcgccatc tcctcggtgc
     3481 tcaatgcggt aatgtcagtg accaccgggt tcgccccgcg cgtgacaata tcctctgact
     3541 gctccggcct gcgaataagc gcattgaccg tgtgcccgcg ctccaccagc agcggctcgg
     3601 ccagaagcgc aactttcccg tgcccgccaa taatcgttac aacagccatc gtctcctcct
     3661 tatgttggtg aaaatagcct acatattcag gctaggtgcg ctgggtagtg atgtctacac
     3721 gcgcctcttc cgcgtaaaga gaaaacgggc gggtgcgccc tgcacacacc ggaacagcag
     3781 actcgctgcc acgggcgcgg cacgtcagaa agcacgtctt caccgggaag gcacagatgc
     3841 gaggatcacc atcgcctact cgttcgtgaa cgcaaacaga gctatgatga agtgctaggt
     3901 ttttatcgct cggcggtacc gcacagaaga tgaggcaggg gatttatggc tgaagaagcc
     3961 gcgccgaaga agcgcccaca cacaccatcc atcgaacacg ccgccgagaa accgtgggtt
     4021 gccatgtggt cactcgtgat cgggttcttt atgatcctgc tcgataccac tatcgtcacc
     4081 gtggcgctgc cccatatgca gcatgagctc aacgcctcgc tctccgccgt gatctgggtg
     4141 accagcgcct acctgctcgc ctatgcggtg ccgctgctga ttaccggccg cctgggcgat
     4201 aggttcgggc agaagcagat gtacctgctt ggtatggtgg tttttaccct ctcttcgctg
     4261 tggtgcgggc tctcgcccaa tgtggagatg ctgattgttg cgcgcgtggt gcaggggata
     4321 ggcgcctccc tgatgacccc gcaaaccatg tcgattatta cgctcatgtt cccgccgcat
     4381 aaacgtgggg tggcgatgag cgtgtggggt gcggcggccg gtatcgcatc gctcgtgggc
     4441 cctatcgctg gcggtctgct tgtggatggc cccggctgga cgtggatctt cttcatcaat
     4501 atccctatcg gcgtgatcgg cacctatctg gcggttcgga atatcccgca ttttccctcc
     4561 aaacagcaca acttcgactg gctgggcgtg gttctttccg ctatcggcct gttcctgatg
     4621 gtctttggta ttcaggaggg ttctacctac gactggggca ttatcaccga gtcgctgtgg
     4681 ggaaccggaa tcccggtgag cgtatggggc atgattatcg cgggcatcat cgtgttcacc
     4741 ctctttatcg tgtggcaggc tgttaaccgt aaagagccgc tggtgccgct gggactgttt
     4801 aaagaccgca acttttcggt gtctaatatt gctatcgcgg cgatgggcgc gcacaccctg
     4861 acgctggcgt tcccaaccac catttacttc cagcaggtgc gcggtatgag ccccacccag
     4921 gcggcactca tgaccgcccc gctcgccctg ttctcgggtg ctctctctcc gctggttggt
     4981 aaacgtttgg gcacgtcaaa ccccaaatgg tacgccgttt cggggtttgc cctgctggtg
     5041 gttggattta ttgttctgcg tgctttgatg acggcggatc agtccctcgc gcttctgctt
     5101 gtaccctttg caattttggg tattggcaac tccatgattt ggggtccgct ggcggtgacc
     5161 gcaacccgca acctgccgcc tcgtttagcg ggtgccgggt cgggcgtgta taacgagact
     5221 cgccaggttg ccagtgtgct cggttcggcg ggtattgcca cgttcatggg cggcctgatt
     5281 accgagcagg ttacacaggc catgcagcgg atgcgtcccg caggtgccgg tgcaggcgga
     5341 ggcgccatga gcgcccccgc cgtcagcggt gaagggatgt ccggcggtca ggttcccgat
     5401 ttcctgcgtg aacctattgc caccgcgatg aacgactcac tgattctggc gctggctctg
     5461 gccgccgtgg gcatggtcgc gtgcctcttc ttcgccaagc cggtagataa aggcgcgtgg
     5521 gcatccgggc agaatgtttc ggatgcgccc agcagcgaaa acaccaaaaa caccagtacc
     5581 gaaagtagca gcgccgaaaa ccccggcgag gcttccagcg cggaagcccc taaagccacc
     5641 ggcgaatcgg ggccagagcc ctctgataaa ggggcagaaa caggctcaaa accctaacga
     5701 tacgcaacaa gacgaaagcg ggagcggctc cttcatcaag aaaccgctcc caatcatgta
     5761 atgcgctgcg catcttatcc agtgtgctct cgaaagaggg cgcatactgc ggcgggatat
     5821 gctccctacg ctgccgcctg atcctcagcg aacgcatccg ggctcactcg cccggtttct
     5881 acgagcacct gtgcgatagc gccgagcgcc tcctcattct gaagcgaaga aatatcgccc
     5941 agcttatgcc cctgatagag ctcacccagc agacggcggg taatcttccc cgaacgagtc
     6001 ttaggaatat cggcgaccgc gaccacatcc ttaggcttag cgatagggcc aatatgttcg
     6061 cgcacatgct gggtgagtgc agtcttcagc tcgtcttcgg tgagtgcccg gccttcgtcg
     6121 gtgagcgtca cataggcgac tgcctggtgg ccggttagct cgtcttccac ggggcacacg
     6181 ccagcctcca ccacggctgg gtgcgtcacg agcgcagact caatttcgat ggtcgaaagg
     6241 cggtgcccgg aaatgttgat cacatcgtcg atgcgcccca gaatgtacac gttgccttca
     6301 tcatcgacct tcgcgccgtc accggcgagg aaccagccgc gcgtaccata gtgcttccaa
     6361 taggaattca ggtagcgttg cgggtcgccc cagacggtgc gtgccatgga ggggccgatc
     6421 ttatcgacca caatgaagcc ctgtttgccg ggctcaacga ggtcaccgtg ctcgtccacc
     6481 acgcgtaccg agactccggg gacttcgcgg gtggcgcatc cgggaagggg agtgcagtgc
     6541 ggggtacctt cggggaaggt cccttcgggc gcgaaggcgg ggtcgtgtgg ccgtggggag
     6601 cagatggtcg agccggtctc ggactgccac catgtatcga taaacgatgc ggtaccccca
     6661 cccacgtgtt tgcgcagcca cttccacgcc tgagggttaa tggactcgcc cacagacccg
     6721 agcagacgca cagttgagaa gtcgtatttt ccgggttcgg ggccgtcagg gaacgccccc
     6781 ataagggaac gaatcagggt gggcgcggtg taataattgg tgacgccgta acgttcgata
     6841 acctcgaaat ggcggccata atgcggagta ttgggggtac cctcgaaaat aacctcggtc
     6901 accccattca cgagcggacc atagatttcg taggtgtgcg cggtcaccca cgcgagatcg
     6961 gcggtacacc agtgcacagt cgattcaacc ttcgccgggt cgttcacggc agacagctca
     7021 tcggggcgca gcaccccgtc gtcatccaca tagtctggca gcagatcgta cagcagcgcg
     7081 tgggtgtatg cggtctgtac caaataccct gccatcgtgt gcaccaggcc cttgggtttg
     7141 cccgtggtgc cggaggtgta gatgataaac agcgggtctt cggcatcgtg cagctcgtac
     7201 tcgtgggtat cgggctgatc gtctaccagg tcgtggtacc aaatatcgcg cccggccgtc
     7261 cagggaacct gcgcgtgcgc cacggggtct gcggcgcttg tacggtccac cacgactacg
     7321 tgctcgatat tgttctcacc tgagcatgct tcatcggcgt tcaccttcac gggcacgacc
     7381 ttgcctcggc ggttctgccc gtcggtggta atcagaacct tcgcgccggt atcttccacc
     7441 cggaatttca gagcctccgc tgagaaccca ccgaacacga gtgagtgaat tgcgccgatg
     7501 cgcgcgcacg caagcgtgaa aataatggtt tcggggataa ccggtaggta gataaccaca
     7561 cggtcgcctt tacgcacgcc gagtttgagc aggccgttgg cggcgcgggc gatgcgtcgc
     7621 tgcagttcgg cgtaggtgat agcttcacgg tcgccgggtt cgccctcgaa atagagggct
     7681 actttgtcgc cgcggcccgc ctccacgtgg cggtccacgc agttgtaggc gacgttgagt
     7741 ttgccgcctt cgaaccactt aatctcgggt acggagtatt cttcgatgcc ctcagcatcg
     7801 gttccgataa cctgcggttt ctggaaggtg tgtgcgttgt cccaggcctt gccccagctt
     7861 aggcgttcgg cttgtttttc ccagaacgct acccgcgcct cgtcagattc gtgcgcgggg
     7921 ttgggggtag gggctagcgg gtttgtgaac gagaaggggc tgggcagtcc cacagtatct
     7981 cccatcggtt gctggcgtta gcaccttcgg cgttatgagc gcgcatgatg cgccaccgca
     8041 gtcgaggttg ctgcgacgtc gtcgagccag gtctctcggt cgctctagat ggattaccaa
     8101 tctagtaaac cctgtagctg gcgcaggtgc aaagacaccc cgtcatattg cgtgtgtgca
     8161 cgccatgttc gtaacattcc gcaatatttg tttgatcccg cacccagaga ttagctctcg
     8221 cgtcgcatac accccaggcg tacagccggc cgggcggaga aactctaacc cgcaaatcta
     8281 atgagcttta gacttaaacc cgttcttaat cttgccccgt aggcttgcat ctcttgatag
     8341 gcttcatcgt aagtgcctga aggttgagcc aaaataaaac actcacggaa ggggcgtctg
     8401 atggctgtta agcgtatcgt tactaatctt gccgctgata aacctgagtc agctgctgct
     8461 ttttaccggg acatcctggg cctggagctg ctcatggatc acggatggat acagacttat
     8521 ggcaatgcgg aaactacgac tgtgcaggtc agcatagcta gtgaaggcgg atcaggtact
     8581 ccggtgcctg atttatcggt tgaagtagat aatcttgatg aaatcctcgc ccgcattcat
     8641 gcggcaggta ttgcgcttga atacggtgtt gctgaagagc cctggggcgt gcggaggttt
     8701 tttgttcgcg atccgctggg gaacctggtg aatattttgc agcatatgta gcggatatca
     8761 tcaaaactat caccagaaga tgggttatta gattgctata agagctgctg gaagcgcagg
     8821 ggcaggcgtt atcctacaga gataaatatt tgcagcctat aaaatttgcg ggtaaataat
     8881 tattttttga actataaaat aatgtaaaaa ctcttgtgtg gtgcagggaa tttaagctac
     8941 gctacaccac agtaggctag aagggcctat gcccaagaaa tttgggctta tgatgattgg
     9001 ataatgcaat gtacaccaaa gcaacgttca ctaaaattac ctctttccgg gccgctactc
     9061 atggatggta ctgggggaat cgtcgtgata tttacggagc cctccggtac gctaataagt
     9121 agtatctttg cctttgggca gaaccggaat aacatacttt tgatttagaa acttctggaa
     9181 attcatgcac acattgtgta atgcaatata ttccacatat tgtttttagg ggcgtaatgt
     9241 atattaagcc agaatttaaa aagatttcct ctttcgcaca tgttacccgt ggctggttct
     9301 ggggaagcta tcgagatatt tttggggcgc tccgtggacc taactctggg ttcgaaggtg
     9361 gcggtggctt caccggcgga ggcgtcagtg gaggctcatg gtagcttccc gccaaggctt
     9421 aaagtgggtg cctcttctaa ggcacccact tttctattgc gttgccaacc aatgtttgca
     9481 gagtccgtgc cattcgcagc gcactttttc acgcatcggg tgtctgctat gacattaatt
     9541 gcttctgctc atatgcagga attaccggtg ctgctggtgg cgggcagttc gtgtaagccc
     9601 gctattttaa gcagaaatat tttcagggaa aattaaaata atcgtgagaa tctcttgcaa
     9661 accatgcaat ttacgggtta gggtaaatct gtgtagataa tatatgtaat ttgagaactt
     9721 taaaatattt aagaaaaggg gaagaatatg tatattaagg cacgttttat gaagatgaac
     9781 tcttttgcag attgtactca cggccttata tacgggaaat accgggatgt tctctccggt
     9841 gcccggcttg tgactcctcc tgaagttgct ctataaatag cgccttgcgc gccaggtgac
     9901 ttgtttatta ttcgcagaaa tcctcataaa agtgggatgc ggtaaaaaat aattaaacga
     9961 gcccatattt ttaatgtgga aagtgacgat aaggaatcct gtggcagagc tatacacaac
    10021 atccggtaac gtgcagaaga tttctcactt tcttcgtagc agctcgaaca atataactgt
    10081 tcgcccgtta cccactcatg aggcttccgc atcaaacacc gactccaccg cagatagcga
    10141 gctggtatct tccgtctcgc gacaccgcag cgtgtaccgt tcaaagctgg ggccggtgga
    10201 ccttctgagc acatcagtaa aacccctagt ggacgccctt aatcccgcta ttaatatgtc
    10261 tcgggtggcc ctcgggctat gccgtaaccc gccggggtgg gtgcgccgca tcccctactg
    10321 gaagaacatt acggcgctgc ccccagccac caccgtatgc gaagacgagc acgggtccgt
    10381 gcagaacacc tcgtacttcg cagacgccct cagcctgcag gacagcaccc tatctttttc
    10441 cgatgtttca cagaacgtat acaccgtttt gaactcggtt ctgaggcggc tggctgaagg
    10501 gcgcacccac gtatctgccg acctgtccgg cggcgtggac tccacggtca tatccgtgct
    10561 cctcgcagcg cagaacattc ccttcaccgc gtttcacgcc gggacggacg ataaagacaa
    10621 ccgcgacaca cagctcgccc agaaaatagc cgaacacttc accatagacc tcattaagct
    10681 tgactcattt acgaaaagca ccgcaggttt caccatcccg gatgagcttc gcgggttttc
    10741 cgaggcaccc cgcgcatggc acgctaacct gccgcacctt accgcccttg tgcgtagcgc
    10801 gcgggaacgc ggctccagca tccactgcct gggaattggc ggggacgagc tgtttgagcc
    10861 catgcccgtt caggcgctgc tctacttcaa acagggtgag aaaatgcggg ctattaaagc
    10921 cattagctcc gtcgcggccg ccgcccgctg gccgaaagta tcgacattac gtgccgcttt
    10981 ctccccagaa acgaaacagc gtgagctgca gcggcgcctg acccgccggg gccagaacat
    11041 ccctgaaaac atcgatgctt tctcctggtt cccgaacttt acgctgccct cctggctatc
    11101 cgaagaagct accgagcaag tcattgagct catgagggcg acccccatcc ctccagagga
    11161 agaagaactg gataaatacc ggttccacat ctacgggtcc ctggaatttc agggggaagt
    11221 gcttcggggc atgaacgagt atttcagcga aaccggcctg gaatttgccg ccccctacct
    11281 tgaggacgac atgatccgct cctccctggt gtacccgggt gttctgagcg ggcacgggat
    11341 gagcaaaccc gtcatcctgg aagccatgaa aggcaccctg cccgagttct tctaccggga
    11401 catctacaaa agcgactaca gcttcgacct gtaccaagac tacgaacgca gcaaagaaaa
    11461 cttcctgaaa atgatcggcg acagtctcct ggcggagctg aaccttgtgg atatagacac
    11521 tgtccgcacg atcgcaaaca gccccctggg cagctcagag acactctacg attttgaacg
    11581 tatgacccac atggaggtat ggctacgtga aaactatgta taaacgctac gcgtcactgc
    11641 ccgagaggtt ctgcatcgcc gatggcgtca aaatttcggg caccgagtcc ggcatcgtgg
    11701 tttttgtgcc cgcccgaagc gcctattttc aaggaaacag caccacagag cacatcttgg
    11761 acctcgtgga gcaggggcgc cgcaactcag aaatcattga ctctttcatt cgccagtaca
    11821 cacaatccga cccggacgag attcgggagg accttgaagg taccctgcgg gaactgtgga
    11881 cgatgggtgt cctagagaaa ggcgaggacc atgggtgata accccaccac cgcaacagac
    11941 gcgcacaccg tcagcagtat caaagcgcgc ctggcggtgt gtgcggcaaa gattattgcg
    12001 cacctgccgg tcaccgttat tgttcgcctg ctgaaaatgt tccggcccct gcagaaaagc
    12061 tcatccattc agcaggcgct cgcggttgat gcgaaagtgc gtgaagtttc cccactgtgc
    12121 cgtggggagc gggggtgcct ggcacggtcc atctcaacct accttttgct ttctctcatg
    12181 cgccggaaag tggtgtgggc ctccgggttc cgggtgaaac cgttccttgc gcacgcatgg
    12241 gtcaccgtcg agggggaacc cattaatgag caccacgatg tgcaggggtt cgtgactgtc
    12301 gcatccacca acccagaagc ccgctagcgc cgtaagcgtt caggcaaaaa cagggtgagg
    12361 gcggcggcac ccaagaagtg aggcgcatga gactatggtg aaagctaaaa ataatgggaa
    12421 gtcatcctgg ggggtagttt tttcgtatct atcccccttt aaggggctgc tgaccgttat
    12481 ctgtttaatg agtctcacaa gctcagccgc gtcgcttctg cagccgttaa tagtgaacga
    12541 tcttgttgat tccgcagggt ccgcccaggg tattggttac ctgccggttc tcattattct
    12601 ggtgctcatt ataggggcca tcctcaacgg tattcagcag tattttattc agaaagtcgc
    12661 cgaatcggtg gcccgtgacg cacgcacgca gctcgtgcgg aaaatactcc gcatccccct
    12721 ggacgcctta gaaaaataca ccaaaggaga catcctttcc cgcgtcatta atgacacgat
    12781 gctgctgcgc cgctgcctca cggaagggtt cgtgcagtcg ttcgtgggta ttttcacgct
    12841 cattggggcg gtgatcggga tgttcttcat cgaccccctg ctgctcgcta tttccgccgt
    12901 catatccctg ctggcggtcg tgtccgtcac gatggcaacc tctaaggtcg aaaaatccag
    12961 cgcgcaaatg cagcaggcgg tgggtgagct gagctcggat gtgtccagcg tgttggaggc
    13021 ctcctcactc gttcggacgg agaacgcggc ggggcaccag tttaagcggc tgcagcagaa
    13081 agttgataat gcgtggctta aggggatcgg agtggcacgg cttgtcgccc tcatcacccc
    13141 catctctgcg gtggccatgc agatcacgtt cctggtggtt cttggcgttg gcggggtcag
    13201 ggtcgcgaac gggataatta ccgtcggcaa cctggtctcg ttcgtcatgt tcctggttat
    13261 gatgatcatg ccgctggggt acattttcgg caccatgagc aatattgccg aagccagcgg
    13321 aggcatcacc cgcatccagg agatcctggg catcccggac gagtaccccg aacagctgga
    13381 cacataccac gaaaaccgtg atatccgctc catcctgctg gataacgtca gctttaaata
    13441 cggtgccgaa cctgaggaag gggcctcacc ctacctgatt tccgggatga cgctcagtat
    13501 cgccccgggg gagaagatcg ccatcgtggg accctccggg tcgggcaaga gcaccctgct
    13561 gcggcttatc gcccggcttt acgaaatctc aggcgggaac ctcctctact ccggcaccgc
    13621 aagctcagac atttccatcc cggctgtgcg cgctaaaatc ggcctggtgc agcaggaatc
    13681 ccccctgatt ctgggcacgc tcctcgataa cgtctacatc tcggggcgcg gcaccgatag
    13741 cgctgccgcg caccgcatcc tcaaagattt ggggctggaa aaagtgcttg aacgttcagg
    13801 gcacggcgtg gacctgaaca ttggcggcag cggcacgtcc ttatccgggg gtgagaagca
    13861 gcggctggcc atagcccgcg tgatcctgaa aaacccgcag gtgtacctgc tggacgagtt
    13921 cacctcccag cttgacggca ttagcgaaga gctggtggtg tctgtgctga acaataacgc
    13981 cgcccccgag tcaaccatga ttatggtggc gcaccgcatg tccaccgtcg ttaacgccga
    14041 catgatttac gtgatggatc acggcaggat cgtcgcccaa ggcacgcacg acatactcat
    14101 ggagttctcc cccctctacc gggagcttgt ctccaatcag ctcatccatt agcggcgggc
    14161 gcagggccta cgcgggggag tgggtgatag tggcactggc ggaaagcccc gcaatattct
    14221 gctcggacgg ggccgcactg ttcaccggct ccagcagcag ggtcgcatcc accacggtca
    14281 cggttgttcg caggctaaac gactcaccca cctggtcgta gtacacgggc acctggctca
    14341 gcagcacctg gttaaacacc tgcatcccct cagctgaggc caccgcgtcc tcagtggtga
    14401 caacgtcgag ggtgccgcgc cactccgtcc cgtagctgtc tgattcccgg aataccgcgg
    14461 tgaaaccggc cccgttgaac gccgcaagcc gcgggttgtt cgaccgggca ccaccagcgc
    14521 tttgagcgag cgcagccacc tgctgctgtt ccccgtcctc ccacagcagg ggcgggcggg
    14581 tctgtatctc gtcggcgaac gtgaacgtgt actcaatgct gaagcgtgcc ccggcgcgca
    14641 gggtggtggt tcccgtgtat tcgccggatg ctgtgtgcgg ggcagcgaac catagcccgg
    14701 cacccccgta gaggccgttg ccgacgctgc cgccgggggt gaacgtgccc ccacctgcgg
    14761 cgagcaggcc ctcccacttg gtggtgcggg atgcgcgcgt gtcggtgagc tgcccgtggt
    14821 acgagtcgag cccgaagaag gtgctgttgg ggttatccat ggtggtatta aacgcctgag
    14881 tgaatacccc gtagtcgacg gcaactacct ggtccgaggc tgcgtaggct ggggccgttg
    14941 cggatgcggc gacggcgggg gcggaccatg cggcgccagc gagtgcgcgg cgccgcgtga
    15001 ggccgcccct gaagggtgcg tgggtcacgt ggactcctgt atgtatttga gagagtgtga
    15061 atgtatgcga tgtgagtgaa tacgacctat ccagtgtagt agacaagtgt gcctgcgcgc
    15121 tgtaatggcg ctattatgtg taggaaatat ttgaaaattt gtgcacttca accccggaca
    15181 tagcggattt ttatgcattc ttgtgctggt gcgcgtcgca gcgcaccgcg cgtaccgcgt
    15241 gtcgggggtg gttgtggtgc gccaattagc tgtatttcat tcactcaatt cacaagcatc
    15301 ctaggagcca cagtggcatt catgaaatct gcgcgccttt ttgccgcgac cgtagtttta
    15361 atcgcagccg gtgccgtccc cgccagcgca agcaccatca acacgtacga tacggacggt
    15421 gatggcatcc cgaacgcgtg ggagatcagc ggctatgacg ccgatggcga cggcacagtt
    15481 gacgttgact acccgggtat gggggccaac ccgtaccgta aagatatttt tgttgagatg
    15541 gactacatgc ccggtgagct cgccaccgaa gccgaccttg accgcattac cgaggtgttc
    15601 gcctccctgc cgttacgtaa ccctgacggt acgcggggtg tgagtatcca cctggatgcc
    15661 gggcccgccc gcagtgcgaa gtacaacctg ggcggcggga acgagattcc gcatcagaag
    15721 cttaacggta tgggggactg ggcggcactg aagaaccgtc atttcgcctc ggcccgtgac
    15781 gctggttttc actacatgat ctggggcgac tattacggca atacgagctc ttcggggctg
    15841 ggtttcacgg gcgctcgcgg gtttattgtg accgttgggc acacctactg gcggggtgcc
    15901 agcagcgata ttagggtggg tacgtttatc cacgagctgg ggcataactt ggggttgcgg
    15961 cacggtgggg ccgatgagga gaactacaag ccgaactatc tgagcattat gaactacgag
    16021 taccagctca gcggcgtgcc gcgcgccggg ggtaagaact acttcgggta ttcaacgcac
    16081 gagcatatgc cgctggatga gaagaacctg gatgagcggc gcgggcttgg ggcgaacgcc
    16141 tacgggtact tgtataaggg taaacctgcg caccgtaacg tggattttaa caagaacggc
    16201 gtgattgatg cgcagccggt tgccgctgat gtgaacggta accggcgcat gagcacgctg
    16261 cgggcgaaga gcgatatgaa gactctacgg tttgcggcca gcgcgacgtc ccagggtgtg
    16321 acgagtaccc cgcggacgga cccctatgag gttgaggtgg actataacga ggtaaccgct
    16381 gaattcgcgc gggaacgtgg cctgctgccc taactgctgt agaggatagg cagctgagtg
    16441 gcgccccgga aggaatatct tggtctgtac ttcaccaagg tttcctttcg gggcgctgca
    16501 cggctaaggc gcctagttgc tggggtattt tgccttcacc cagcgctcaa acacgccaat
    16561 gagcgcatct gtgagcttac ccagcaccgc cagcagcaca attgccagca gcagacggtc
    16621 ggtgcgcccg ttgttctgcg aatctgtgag caggtacccc aagcccatgg aggcccccaa
    16681 tagctcggca gccaccagga acagccaggc ctgcgctaac gccaggcgca gccccgacac
    16741 cacggacggc agcacggcgg gcagctggac ggtagtgaaa agtttaacgc cccggtatcc
    16801 gaaggcgcgt gcggcctcta caagtttagg atccacgtgt gccagtgccg ccgagacggt
    16861 ggtgtacacg gggaagaacg cgccgattgc cacaagtgtt actttagagt tttcgccgat
    16921 gccgatccac agcagcagca acggaaccca ggcgagtgag ggcacggcgc gtaaagcccc
    16981 aatggtgggt gctgcggcga tgcgcgcggg cccccacagt ccgataagcg cccccagaac
    17041 cagccccagc accgcgccga tgctgaaccc gagtaccacc cgctgggtgg agattaccag
    17101 gtgggttgct agctcgccgc gttgggccag ctcggttccg gcggctatga cgcgggtggg
    17161 ggagggcagc tgcaccgcgg tgaatacccc ggcggtgctc agcacgtacc acagcgtgat
    17221 gagcgctgca ggcaggataa gccccacata gtgtttggca cccaggggca gggcgcgctt
    17281 tggccggggc tggccgcggt gggagctcgc caattgggtg cgcccggcag cggtgctggc
    17341 ggctgccgtg cgggctgcgg cggtttctgc ggctgcggat ttcgtgtgtt tgggggtgtc
    17401 tgaaagttct ggggtgtcgg aaattttgtc gagggttaca ctcatggcta gctcaccgtc
    17461 ttcttcacgt tctcaatggc ggcgctgtcg gctttcttgg cgtatgtgtc gtccacgatg
    17521 ctgctcagcg ccttatcaat gtctgactgg ttggggacgt ccccggattc gacgaggatc
    17581 gggccaacac ctttgagcac ctgcacctgc ttgtcccctg ggattgggtc aatattcagg
    17641 tgggttcgtt ccatcacgag tttggcggtt tctaacttaa taccggactc gtcggcgaga
    17701 atctgggttg cttcagcagt gttttccagc gcccatttgc gggcatactc atacacgttc
    17761 acgatggttt gcgccgcgtc cggattgtct gtgaggaact gctcggtggc gttgagaaac
    17821 ccgtacgtat tgaagtctag gttgcggtag aacagcacat catggctttc gatttccgcg
    17881 ctggccataa tcgggtcgag cccgctccag gcgttgacct gcccgttatc gagggcggtc
    17941 cgcccatcgg cgtgctgcag gttctggatg gttacctctt tcgccgcgat gccttctttc
    18001 ttgagcgctt ggagcagcag gaagtacggg tcggttcctt tggtgaccgc caccgactta
    18061 ccctttaaat ctgatactgc atgaatattc gagtttttgg tggtgaccag cgccgaccat
    18121 tcgggctgcg agtacaggtc aatcacctta atgggtgagc cgttcgcgcg ggccagcagc
    18181 gcggcagaac cggcggttga gcccacatca atgtttcccg aacgcagagc ctcattggct
    18241 ttgtttgacc cggctgattt gacccattcc agctttttac ctttttcctg cagggccttc
    18301 tctaaccacc ctttcttttt aataacaagg gagagcgggt tgtaggtggc gtaatccacg
    18361 gtcacggtgt ctttgccttt tgctgctccc gcgccggggg ttcctgcgcc ttctccggcg
    18421 catccggcaa gaacggtggt gagggcgctg aaggccagca agcccttaag agcttcggct
    18481 ctggtgatgg ctgtcatggg taatccttgg gtgtctgatg gggtgaagaa aacagtaaat
    18541 tgtgaataat tattcactaa gagggggcgc gcagcggctc tgggtgtacg cgggagtcag
    18601 cgccctgccc taagcgggaa ccggggtggt atcggctttt tccacgccga gctctgtcag
    18661 cagctcagcc cgcagggcag ttagctcttt gctggcccta tcacgcgggt gggcgtcgct
    18721 aatggtgact acacgtgtga tcgttgcggg cgcatcgggc gcggatttgc cgagcacaat
    18781 cacccggtct gagaggtaca gtgcctcttc cacatcgtgg gtgaccagca gaatcgtggt
    18841 cgggtcttgc cggtgaatat ccagcagcaa atcctgcatt ttaatgcggg tcagcgcatc
    18901 caacgcccca aacggttcgt ccagcagcag caccccgggt tcacgcgcca gcgccctcgc
    18961 caaagaaacc ctctgagcca ttccgccgga gatttctttg gggcggtgcg tggcgtagtc
    19021 ggtgagcccc accaggcgca gcagctcacg gatgcgctcc tgtgctcgtg tttttggggt
    19081 gccttggggc agtccgagcg ccacattatc ggcgacggtg cgccagggca gcaggcgcgg
    19141 ctcctgaaaa ccgattgcca cccgctgatc aagcccgctc accggggtgt cgccgatgcg
    19201 cacctgcccg cccgtaatgc ggttcagtcc ggcggcggcc cgcagcagcg ttgacttgcc
    19261 gcatcctgat gcgccaatga ccgaaataat ttctcccgcg gcggcggtaa aacttacttc
    19321 gcgaagcacc tcgtgcgtgt tcttgccgga ctgcgggaac gactggctga cggcgtcgaa
    19381 agtgatcgtc tgggcgttgg cgggtagctg ggtgtggtga ttctgtgtca tgttacttcc
    19441 atcggtcctg gcgttagcac ccgctagggt tgctgcgacg tcgtcgagcc aggtctctca
    19501 gtcgctctgg atgggttacg cctataaccc tagaggagcg cgccattgca gcgaaaacac
    19561 atgacgtacc gtgactaacg gtgactaaat attgcatgag tcatgcgaaa tattacggtg
    19621 cggagtcaca aaaattaatg ttcgtcatat actgttcacc cccatctgcg aggggataca
    19681 ctcaaaacgc aaggattatg agtcccggcg taaagctctg gctagccggg cggcaaccct
    19741 ctcccgtagc ggggtgcccc agatgatgat ctggcttcaa ggaacacgaa gcaagtacgg
    19801 cgcgaatgcg ccacctgcac aacttggaac accaagaagg ccaccaccta taaggaggcg
    19861 gcgcgcgggg tgcaggaaca ccctaacatt cgcgaaagga tacgtagatg gctgagcaga
    19921 agaagcgcat cgcagttaac gcattcgaca tgacctgtgt gggtcaccag agcttcgacc
    19981 tctggcgcca cccccgctcc cgggctaccg agtacaacac catcaaatac tggactgact
    20041 tggcacagat ccttgagaag ggcttcttcg acggcgtatt cctagccgat gttgtgggca
    20101 tctacgatat ttacaagaac tccgccgcgc ccgctatcga aggcggcgct caggtgcccg
    20161 tgaacgatcc gttcatgcag atctccgcaa tggccgccgt aaccgagcac ctgggcttcg
    20221 gtgtgacctc agccgtcacc tacgagcagc cttacacgct cgcacgcaag tacgcttctc
    20281 tcgaccacct cactaacggg cgtgtgggct tcaatgtggt gacctcatac ctgccttccg
    20341 cagccgaatg tcagggcctc gaaacccaga ttgagcacga cacccgatac gaactcgccg
    20401 aagagttcct ggatgtctgc tacaagctct gggaaggctc ctgggaagac ggcgcggtcg
    20461 tcaaagaccg cgagaagggt atctacgccg accccgccaa ggtgcacccg attcagcaca
    20521 agggtaagta cttcagcgtg cctggtgcgg gtctgaccga gcccagcccc caacgcaccc
    20581 ccgtgatttt ccaggcgggc gcatccagcc gcgggcagaa gttctcgggc aagcatgccg
    20641 aagttgtgtt tatcggtgcg ctccgccccg atctgacccg cattattacc gaccgtatcc
    20701 gtgaccgcgc cgaagagaac ggccgcggcc gcgacgaaat caaggttttc gcgatgctct
    20761 ccattattgt ggacgagacc gaagagaagg cgaaggcaaa gtacgaagag taccgcaagt
    20821 acgtgaacct ggaatcttcg caggccatta tcggcggctg gtccggcgtg gatctttccc
    20881 agttcgacga ggacgaggta ctcaactatg tgaagaccga gtcgattcag tccttcctca
    20941 cccccttcac cctgcaagcc aaggataagc agtggacgcg taaggatatt gccgagcact
    21001 gcactattgg cggtatgggc gaggttattg tgggcgaccc gcagcaggtg gccgacgaac
    21061 tcgaacgctg gattgatgaa ggcggactgg acggtattaa cctggcatac cacgtttcgc
    21121 ccggctcctt cgaggacttc attgagttcg tggttcccga gctgcaaaag cgtgggcgct
    21181 accgcacttc ctatgagggt gagaccctgc gcgaaagcct gttcggtaag ggccagacta
    21241 aggtcgcaga ctcccatccg gccgcgaaat accgcggcgc ctacgtgggt aagccctcca
    21301 cggcagatac cccggcacgc gctatcgcga actaaacccg ctgcgcctgc gcgcatggtt
    21361 gcaaaatgtc ccctcctagg gcaataaaaa gagcctttat ttgaataaag cattaaaatg
    21421 ccgctttatt cgaataaagg ctctttttca cgcacgttta gaatggggtg catgagcgaa
    21481 acaaccctgt acgaccttca aacccgctgc ctgtgtacaa gcggcgaggt atacggtgcc
    21541 tgctgcgggc ggtacctggg cgagtttgcc gcatccggaa tcctgaacgc gcccacaccg
    21601 ctggctctga tgcgctcgcg tttcaccgcc ttcgccctgc acgatgcgcc ctacctgttg
    21661 gcgagctggc acccgcatac gcgccccgcc gagctggata cagatgaaac attgcgctgg
    21721 taccggctgg atatcctggg ctcttcgagc ggtcccttcg atgcggcggg cacggtcgag
    21781 ttcgtggcgt actaccgctc ggttcccggc acgcccgccg aagaacgtgt gaaaggcacc
    21841 atgcacgaaa aatcccgctt caagaaagta aacggcacct ggtactacct ggacggtgag
    21901 gtcagctaag ttcttcccaa ccgggtggca tggcaaaaac attcctctta tggtatgttt
    21961 ttgccatgat gtcagtcgca gaatatgccc agcacgccgg ggtgagtccc cgaagcgtgc
    22021 gtgcacgcct tgaacgaggg tctttgcgcg gacaaaaaat cgccgggcgg tggatggttt
    22081 cagataaccc gcacgagcat tactccgcac atgggcgcaa aatctcgatg gcatccttca
    22141 atcagcttgc cgcctatctt gacggtaaca gtgcatccct tacccccgat gcacgccgcc
    22201 gtgccaaaga acgtgcacat aacatctccg aacgtggggt agaagctctt aggcagtatg
    22261 cagtgcgtgc agatgcgaaa cctcaattct atgccgtgcc ttctgctgac ctgcatgacc
    22321 tgatgggcga acgcgcatta gtgcttacgg gtgtcagtca cgaatattcg gaaatttacg
    22381 gggctaccgt agacgcatat gtaactcccc gcgacctcga atccctgaaa tttatctacg
    22441 cactacgtga agttcatgct caggatgcca acgtcattct tcgcgtaatc aaagagttac
    22501 ctaagattcg ccccttgcat gttgcagttg atctcctaat ttccaaagac ccgagaagcg
    22561 agcgggaagc ggaacgccta gtgaaaggac tcataagccg tgcctgatca gaaaacggtg
    22621 aaaatcccag cccagggcgc agagcttgaa tcctggcttg ggttggcaga catctccgat
    22681 ctagttcctc agggttggtc cctcgccggt ggaagtatga tgaggttact cgcgtgtgag
    22741 cgtgggtatg agggctctcg ggcaacccga gatattgacg tcgttcttaa tattcgcgct
    22801 cgacgtcggc ttattgggga attcgtccat gcactcaaga gcacaggatt cgtcattgat
    22861 gggtataacg tttccggaca aaaccaccga tgggtgcgag gcttagccca aattgatgta
    22921 ttggtgcctt cgggacaatc cgagaaaacc ctgtcctatg acttttccgg gctgggaaaa
    22981 gtcctgatga ctcgcggcgc ccaatttggc atagaccgca catcgtcagt tgctgtggaa
    23041 tgcgcgggtc gcacgttcct ggtaaatcgc cctgacgctt tgggtgcgct ctatgagaaa
    23101 tgctccgctc ttttgaataa tggtgacaca cataaacagc gccattttca tgacattttg
    23161 gtacttgtct gcctactttc aacctctgaa cgccgagacc tgataggact tagcggcaaa
    23221 caaaggtcaa gactggcatg ggggctgcgc agagctttag cggaacccgg tattggccgt
    23281 cctcatgagc gtgagatggc tcagaatatt gtgagcttcc tcaatgaaag tctcaaaaac
    23341 tagtcctgcg tttgctatgt ttatgccatg agtgacgtta tctcgcagga atctttcaac
    23401 atgctcgccc tctatttcaa cgggggaggg cacctgctta ccccggacgc gcgccatagc
    23461 gccgccgaac gcgcccgcat cctctgtgct cacgggctcg atgcactccg gcagtacacg
    23521 caccgcaccg ggatgactgt gcactactac gtggcaccct acgatacgag cgacctgctg
    23581 cgaacgggcg cggatgcgct cgcgctcacc ggggctcggc acgaactttc gaggataaaa
    23641 acttccctga tcgacgctta cattctgccc gacgacctca caaaatttgc cccgagttgg
    23701 ggtttggagc ctgccccttc cgagcgggcg aatgtgattc tgcgcgaggt ttccaccctt
    23761 ccgcgggtgc tgcgcctgca tgtggcggca gatgcgctgc acgcctatga ggctggcgcc
    23821 gctggcgaga gtgcccgaaa agcagcccag cgcatcctgg gcgagctgtg cagttcttga
    23881 aagctgctgt cagtttttgg cgtgcaccat cgggtaaata gggggatttg ccgcggaaat
    23941 aatggttacc ccgcgaacct gcttcggctc tgagaaaagt tttggaaatt atgatgagga
    24001 cctattgcat acttccccgg tggtttgata cagttgaggg gctagccaga gtcgcaataa
    24061 gtttattaca gggacgagaa cttattgtgg gtgttctatt gaggatgcaa agaatggata
    24121 gcattgagag cttccgaaag ctgatattgg gctcctattg tgtgatagga acagttttac
    24181 actctcacat atcctaagtt tccatttgat gtcgcaccac tttgtgatgt ggtggccgta
    24241 gtatagcgct attaatgcac agagcaagtg tattgtggcg tggtagctag gtgataggca
    24301 tcatcgtaga ggaaatatac tttgctgaca aatatagaga gcttaacttt ttctagcgaa
    24361 ctcattcttc aagtctttta aaaattaagc ggcaattatt ttctgctgca atttttaata
    24421 gtggaatgtt ttggggaact gctggctagg tctctattct cgaccaccca aaatggtcat
    24481 taaaaactct ataagtttcc ttttgagggg gttgcacccc tgcaataaag gaggtgggtt
    24541 ccaagctgtc acctttggaa cgttgtcatc ttggaaccca gccaaagttt gatggaaaac
    24601 atcaaactat tgattaacca caatcattcc tgaggctatt caggaattca taaggaggat
    24661 aaccatggct aaggatacca tgttcatgga agaactgacc gaccaggagc tggagcaggt
    24721 taacggcggc tgttacagca gctgtggata ctacggtggc agctatggcg gtagctacgg
    24781 cggtagctac ggtggcagca gcagcagcta ctacggtggt agctacagcg gcggcggcta
    24841 ctactacgct gctgttgggt acggctactc ctgctaataa caaaacatag acaaggggaa
    24901 tactgagtgc taatcaggga acttcttcct gagctggata atgaacagtt ccagcaactg
    24961 gtgtcagatg tgtcagacgt ttctttactc gaccggttag acaccacctc agattcccca
    25021 cctgttgggc ggccgtcagc tccagtgcct tcagcactgg ggccgacggc cgaacctgct
    25081 atgttttaca cgctttttgc gtggcttttt gagagtgaat ataagcgcgt agtacaggct
    25141 gttcgtgcct cacactatat tgagagagaa cacttcccaa acattgttgg tgggctcctt
    25201 gatgagttca cggtgcgcct ggcgaatttc tatattcggc cgttggtcgc ccatattaag
    25261 aaagtttcct ctgaagggct gctgcaaggg gacactccgg aagagcggta catagactac
    25321 tgccgccgct ggcctaaaga tttcatggat ggtttctata cgagctatcc tcttctgcgg
    25381 cgggtccaca gtattattgt gcatcaattc cacgctatag tggcggagct ttttgaacgc
    25441 atccaggccc aagaaagcgg cattcgtgag cttttagggg cgcaaaatgc tgagtccctc
    25501 acccttgagt ctctcactat ggcgggtgac taccataacg gtggacgcac cggctgcctg
    25561 ctggtgttta gtcaggggac ggtggcttat aaaccacgta gcgttgatgg cgaacgggcg
    25621 ttctacagga tcgttcagaa acttgcggaa cagggcgctc cccgcatgcg tgccgcccgg
    25681 gtcgttcagg gtgaagacta cgggttcatg gagtttattg agagagaaga cgtagacttc
    25741 acggccgaaa aattcttaga gtcttcgggg cagctgtcag ctcttttcta tgctctgctg
    25801 ggtaaagaca tgcacgagga gaacctcatc ccaacgagcg agggtgctgt ccctattgac
    25861 ctcgaaacaa tactgcactg ttcacacctt ctgaacgatg gtaaagcaga catgcccgac
    25921 aacagcgctt tgttacataa agaacgcggt atttgcacca gcgctttact gcccacccgg
    25981 ctggtacgta aagacccctc aaaagggtat gtagatattg gctttatccg gggtgagcag
    26041 ggggcaaacc ccttcaaagg tacggtcatt gagcaacctt tccgcgatga tgctattgtc
    26101 cggtctgtcc ggtattctga cctcggcggc cctcaacagg gcaacgatcc ggatacccac
    26161 acccttgaga aacggcgcgc cacggaggtc gcccgtgccc gcgggtttgt gcgcgggttt
    26221 gagcagatgt accggtgggt gtgtgagcac cgtgacgcta tgctggagct ggtacgcagc
    26281 gaatgcgctg cgctgactct tcgggccgtg ctgcagccca ccatgcaata cgagcagctg
    26341 gtacggatgc tcggcagccc cgaggcgtta tcctctaaaa gtgtttttgc gacagtggcg
    26401 ctacgtaccg cagcctttga cgacgatcgt tccctggagc tggtcttagc agaggtagag
    26461 tcactgtggc agctcgatat cccgttcttt aaacatcggg ccgatcgtac cgcgatcatg
    26521 acacccgacg ggcaagaggt gggcttgggc attaaaacca gcgctcttga ggagactctc
    26581 aaccacattt cccacatggg cgaagacgac cttgacgagc agctgaacca gatctggtct
    26641 gcttttatct ccccgtaccc cgcgaatact ctagcggatg aaccggcaga catccggcag
    26701 ggccgtgggg gagagcggga agagcgtgaa ctcagcacca tgatcgccga ccggctggtg
    26761 gctacggttc atccaggcac cgccccggag gatccgtgga cgtgggttag ccctgtcccg
    26821 agtagccagc agcatcatca tggcatttgg aatactgatg ttttgcagac ggatctctac
    26881 ggcggctcag tgggtattgc gttggcgtta gcgcaagcgg cacacgtgct ggggcaccaa
    26941 gaatatgctg agactgctca ccgcgtattc gacccgctag ctgagactat tctttcgggg
    27001 gaaaagccgc ttaagctgcc tgagtatata cgcgacatgg cttttgctgg tgaacccggt
    27061 atcgctttcg ctcttgccgg tgccgcccgc taccttggtg atacgcggct aaaagatgcc
    27121 gctcttgagc tggggaacca ggtggctgca cgtatagcga aggtggagca cccaaccccc
    27181 ggctatctga gcggccatgt gggcgcggca actcttctgc tggggcatga gctggccact
    27241 gaccgtcagg cgctgctggc tgtgttagac cggcacgccc aggacattat tgctggccgt
    27301 attgatgatg cgtggtgggc acagagcggg ttcgccaccg gcatgagctc gtcaattttc
    27361 gccctcagcc ggtggagcca agacatgccc tcaccagagc gtgcccggca ggcagttgcc
    27421 tttttactga accgcttaga tgaacttgat aacggggaat actggcagat gcgggtacct
    27481 attggggaga gcgcccacga cggcacctgg tgccacggta gcgcgggtgt cgccttagcc
    27541 ttagcggctg ttcactgttg gctccctgag ctttctaacc gcgcgagcct tgaccgtgca
    27601 gtccggcgtt ccctgcagga gggaaccaag cgtaacttca cctcttgcca cggtgccctg
    27661 ggaacccttg acgtccttga atgggtggtc tcgcacgttc ccgatgtgtc cactgcagag
    27721 gccgtccata atgccgtcaa gaacggttat aacgtttccc tgctgcgtga gacgctgaac
    27781 gataaatctg ttcgttactc tctgacgcct tctctgatgg tgggcacctc cggggtgctg
    27841 tcgtggttga ctcgccgggc aggggatacc cacctatata cccccatagt tcctgactcg
    27901 gccgaggctc actaataggc agtgctcagg gttattttgg tgtaatggat aacacctctc
    27961 attgagggtg gaatactctg attttcccag aaaatctatt gcacctaccc cggggatttg
    28021 ttatagttga gtagctaacc agaaacgcaa tagatttatt acagggacga aaatttattg
    28081 cgggtattct attgaagatg caaagaatag gtagcgttga gagcttccga gaactaatat
    28141 tgggccccta aatttgatag ggaaagtttt acactctcaa gcatcctaaa gtttccacat
    28201 gacgtagcgc tactctactg tgtagtggcc atgttgttgc gccaaaatag tgcagacagc
    28261 atatacgacg cagtgtgtgg cgtgatctga atattggact ttgccttact gacgaacaca
    28321 tatttacaga tctattagaa tacctatttc cgctgcacat ttctttagcg atggaatgtt
    28381 gtcagaggtg actggttagt ttatacctta aaaccccact ggggaattta aaactttaca
    28441 agtttccttt ttgtttgggt tacctaaaac ccagatgaaa aggaggtggg ttccaacgtg
    28501 gcgccttgga acgttgtcat tgcggaaccc agctagagtt tgatggtaaa acatcaaact
    28561 gacaccgata atactattcc tgaaattggt tcaggaatac ataaggagga taaccatgcc
    28621 caaggatatc acgcttctgg aagagatctc cgatcaggaa ctcggtcagg ttaacggtgg
    28681 cggctcccac ggtggcggct actacagctc cgttggtggc ggcagctacg gcggcggcta
    28741 ctgcggtggc ggctgcggcg gctacggcta cggctttggc ttctggggcg gcagcttctc
    28801 ctaaatccag aggataagta aatacgatag ataaggagaa ttcaggtgtt aatcagggaa
    28861 cttcttcctg aactggatga ggaacaattc caacgcctag catcttacgt atctagcact
    28921 tcgttactag aacggatagg caccaccgca tccgaagcgc ctgactccga ttttattgta
    28981 cggttgtcgg ctccggtgtc ttcggcactg gggccgactg ccgagccctc catgttccac
    29041 gcgctcatcg cccaactggc ggagaacgaa cgtggaaacg tcgaacacgc catcacctca
    29101 tcgggctacg ctgtaacgtc gcagatcccc cgtttaacca accaattctt ggataaccta
    29161 acggcgcgtt taaacaattt ctacctcaga ccactggttg cccacatcaa aaaggcctct
    29221 gcgcaggggc tattgcaggc agacacaccg gaagggcgct acgaagacta ctgccgccgt
    29281 tggcacgaag aactaagcga tgatttccac gcaagctacc cacttctgaa ccgtatccac
    29341 caggtgacgg tgcagcaatt tcacgcgatg atcgccgaga ttttcgagcg tgtccgcacc
    29401 cacgaaaacg atatccgtga gcttttgaat accacggatg ccgcaccact tcagcttgaa
    29461 tcttttgggc tgccccgaac tcgttacggc ggcgggcgtg ctggctgcct cctcaaattc
    29521 acgcagggca cagtggtcta caaatcacgc aacgttgaag gcgagcgagc attctggcag
    29581 atcgttcaag accttactca gcagggggca cccactatgc gtgccgcccg ggtagtccag
    29641 ggtgagggtt acggcttcat ggagtttatt aaagctgagg aggtagattt ctcaggcgaa
    29701 gacttcttag aagcctccgg ccggctagcg ggtttgctct acgcattgca gggcaaagat
    29761 atgcacgcca agaacctgat ccccctggcc accgggcccg tgccaattga ccttgagacg
    29821 gtgcttcacc ccatatacat cctcgccgac gacacccctc aaccgcctga aggcagcgcc
    29881 cacctgcgaa aactccgtgg gatttccaat agcgcgtttc tgcccacccg tattacgcgc
    29941 cgcgacgcct ccctggggta ccgtgacgtc ggcttcctcc acggggagca ggggaatgac
    30001 ccgtttaacg aggtcattgt tgagcgtccc ttccgggacg atgctgccgc ccgaatgaac
    30061 cgcgaaccgg ccccagcccc agaggagaac caagaagcgg caagcatggt ggcgctcgtc
    30121 ggcgacgaat ctagtgttga ggtgctggaa gagcggcgtc tctatgaagc tgcccgtgcc
    30181 cgtgccttcg cccgagggtt tactcagatg caccaatgga tctgtgagca ccgcgaggcg
    30241 atgcttgagg cggttcgcgc gaactttacc gggctgatgc ttcgcgccct gctgcaatca
    30301 accaggtttt acacccaaat ccttaagatg ctcagcagtc ccgaggcgct cgcatcccaa
    30361 gaagtgttcg ccacggtagg gctgcgcgcc gccaccctaa gccacaaccg ccccctggat
    30421 atggttgcgg ctgaagcgga agctctctgg cggttcgacg tacccttctt catgcaccag
    30481 acggatggct ctgacatcgt atcgtttgag ggtaaaccgg tggggctcag cattaaaggc
    30541 agcgccctgg aagaaaccct gcggcatatc gccgcccttg acgagaatga cctagaggag
    30601 cagctccaac agatctgggc cgccttcatc tcaccctacc cggcgaacac cctggccaat
    30661 agcccggcag aattactctc cgccggagaa gacgaacagc acgaacagga gctttgcgcc
    30721 gcgatcgcag accagctgac gggcactctg cgcctaggag gcagtgagca agactcccgg
    30781 acgtggctcg cacctaaccc cgggctctgg cagcagcata ttggtgcatg gcaaaccacg
    30841 gttcttggga tagacctgta caccgggtcg gtcgggcctg cgatggccct agcccaggca
    30901 gcacacacgc taggaaacgc ggagtacgct caggctgcgc accgtgtgtt agacccgata
    30961 gcgcaggatg tcttcgataa gaggctcttt agcattcccc cggagacctg cgacggtgtc
    31021 tcaggcggtg aggcgggtat cgcgctctca cttgccagcg ccgcagagta cttggacgac
    31081 ccccggctga aagaagccgc cattatgctt ggcgaccggg ttgccgcccg catggagcag
    31141 gtggagcatc cgatgccggg gtacctggac aaccaggtag gcgccgccac actacttctg
    31201 gggtataacc tcgctaccaa tcgtgccgcc ctgctggagg tgctcgaaaa gcacgccctg
    31261 gatattgtcg ctggccgggt tgaggagaac tggtggaatg tgagcgggtt cgcctacggg
    31321 gtgagcgggt caatttttgc tctggcccgc tgggggcagg agatgcccac acctgggcgc
    31381 gctcaacatg ccgtgaagat tctcctgcag cggctgaaca gtttcaggta tccggaaggc
    31441 tggcgggccc agctctccga acgcagcggc acaggcgacg cgcacaccgg cggtacgtgg
    31501 tgctctggct ctgcgggtat cgctcttgca ctcgcagccg tacacgtgtg gatgccagag
    31561 ttctccccgc gtactgagct cgaccgggcg gtgcagtacg cgttccgtac cggaactagg
    31621 agtaacttga cgttgtgcca cggggactta ggaaccctgg aggtgctcaa ctggattatt
    31681 gctcgcgttc ccgatgtgcc cggtgccgag gatatccggg cagccgtcaa aaacgggtac
    31741 ggcccctcag ttattcgcgc gacacttgac gataagtctt cacggtactc actgaccccg
    31801 tcactgctgg tgggtacctc cggggtactg tcgtggctgg ctcaccgttt agggggaggg
    31861 cgtttataca cccccgtcat tcctgacgtg agtgaggacc ggtaaaatat ggggtttcca
    31921 gcggttctcc aagcggctgc tactgagtgc gggctaggtg tcggcgcgtc cgtattgcag
    31981 cattacgggc ggtatcagac gatatctgat ctgcgcctca ttgccgaacc cgggcgtgaa
    32041 ggcctgagta tgctccaagt gcgcaacctt ctcatggcag aaggcatgga cgtcggggcg
    32101 tacaaagcta actcgctgga acagctgcgc gatatcggca agccagctat tctgcactgg
    32161 aacaactccc actatgtggt gctggtacgc atccgtaaag accgcgtaca tattatggac
    32221 cccgcaacgg ggatgaaagt tatccccctt caggaagctg aaggctcatt ctccggtagc
    32281 gtgctggttc ccaccccccg gaaagacttt aaaaagaaat cccgaaaagt cttccaagac
    32341 tggcagctaa acacgttctt cacgaaaaag atgttcgccc agtacgcggt tttcgtggtg
    32401 ctgctggtga ttacctacag cgtcacgttc gccgtgccgg tggtgatcca aagcgtggtg
    32461 gacgcccaac tcagaggcca tgaagacgcc atcctcgtcg caactatcgg cgtggttgtt
    32521 ggcgtggcgg gctactacct ggtgtccatc gcccgcgccg cggctttggc tagtatcgtc
    32581 tcgtccatcg ggtaccagct gctgggcggg atgttcaaaa ggctgctgaa gctgccgctg
    32641 acctactttg cgctccgctc cccgggcgat attctgtacc gtctttccag cgtcaatacg
    32701 ctgcggaact ttctgtccac gaacctgact gagctcgtga ttaatatcgg tacgatgatc
    32761 gtgattctcg tcttcatcgc ccagcagtca cgcgaaatcc tcattatcac cttcgtggta
    32821 cttgccgtgc tgatgctgat ctggttcgtg acggcacgcc ccacctccca ggcgctcgac
    32881 gccgaatatg cgcacgcctc agaagcccag gtggtcgaac ttgatgctat taacaccgtg
    32941 gcatccatga aaatgactgg ttcggcaagc tccacatatg agacgtggcg tgaggcgtac
    33001 aaacagtcgc ttgcctcaat gcgccgccgc atggtgctgc agcagggtgt gcttggttcc
    33061 gcagcttccg tggtgcagct gggcgggccg ctgattctgc tgctggcttc gcttcctctg
    33121 gtgaatcagg gtgtgctcac gctcgggcag gctattgcca ccgagggtat ttctgccatg
    33181 ctgttctcct ctatttcgtc aacgatgttc ggcattatga acattattgc cgtggaccgg
    33241 gcggtggcgc gtatcgttga tattcagcgt tacgaccctg agcaggatgg cggcaccatc
    33301 actaagcttg ccagcagcga tattgagctt gagaacgtga actttaccta ccccggcgga
    33361 acgcagcccg tgctttctga ggtgtctatt acggtgccag aggggcatga catagccctt
    33421 gtgggctcat ccgggtcggg caagagcacg ctggctatgc tgctatgttc gctgtacagc
    33481 ccggtgtccg gcactattcg gatgggcggg atcaatgtgc aggattattc cttggatgca
    33541 cttcgctccc acattgggta tgttccgcag cagctgcaga caaggggcgg caccctgtac
    33601 gagaacctca cggcggggct tgacgatggc cgaacccgcg aggagatcga agcggatgtg
    33661 ctgagcatgg gtattctgga ttttgtgaag ggtctgccca tggggtttga cacgatcatg
    33721 tccagtgatg gtgagaactt ctcaggcggg cagcgtcagc gcatcgccat tgtgacggcg
    33781 ctgctgcggc gcccgcgcat cctggtgctg gatgaggcaa cgagcgcgtt agataccacc
    33841 actgagcgtc aggtgacgga gctgattgca cggtataagt gcacgaaggt tgtggtggcg
    33901 caccgtctct ccactattcg caacgcccag cggattattg ttttggaggg tgggcgcatt
    33961 atccagagcg gaagccatga tgagctgatc cgggtccctg gccgctaccg ggatctgtac
    34021 tacctggagg accctgaaag catcgcacaa gagatccgcg cccatgaggc accgcagact
    34081 caagggaagc cgcaggccca ggaaccccag gacgagcagc gggaatacga agaaagcctg
    34141 tatgaccata tggcgtgggt gggggttgaa tctgccccgc ggtttaggtg caggacctca
    34201 ttctggagca gcggctccag gtaccgggag gctactgcgg ccaggatgca taaggccgcc
    34261 gataactccc ggtggctggg gtaagcctgc cttccggcga agaaatcggt atgtgcagga
    34321 atctgcgggg catgtcagtg aaactaacga tacagctgcc atggcatgac gggtaaaaca
    34381 tgacggcaca tgctctctaa actatggtga acaacctcta tgggggggta tttctgtagc
    34441 ttggtcgtgt cttcatgcag cttagtcgat acccatcctg cataggttcg ccgcatgtta
    34501 ggctgtgcat gaggtgatgt ggtgaagctg agattatgcg aggatcctgc ctatcaggaa
    34561 cccgaggtga gtatcgttta tgcccagaag gatgtgcggg tcagccgcat cgtcgatttt
    34621 gtggaatcgg tggagcagcg gattaaatgc gaaaacggaa gcaccgacat catggtgaat
    34681 gcttcagata ttttctattg tgaaagcgtt aagaaaacaa cgtttgtgca tgtagcagga
    34741 aatacgtata ggactgacca taggctctac gaccttgcgg agaaacttaa agattgtgga
    34801 tttgtgcggg tgagtaagtc atgcattctc aacattaacg ttcttgagag tgttaaaccg
    34861 ctttttaata gccgcatgga agccatatta acaaccggcg atagagtcta tataaatcgc
    34921 acatacctca aaaacgtcaa acaagcgttg aaaggatacg gtgcatgaga aaacttgctg
    34981 ttaatatttg tgcgaccacg ggtatctccc tcattttact ggccgtcatc ggtctgttat
    35041 caggtggaac gtatctttac cttgtgggag ttttccaagt ccttacgacc aatatgatga
    35101 ttcatgtggg tatgctgctg gtttcgcgca tggcactgaa atatcccctg ttggaggcgc
    35161 ttgtcgatat agcccttatc cttgtcatga tctgcggcag tgggctggcg ttcggctggt
    35221 tctccagcac accgctctgg atcctgtgca ttctgggaat cgtgatgtat ggcgcctcaa
    35281 ccgccctgaa tattttacat atgcgccggg aggttcagga aataaatatg ctcattgttc
    35341 gacgaaaatt tacttaaaac cactatccct gaaagcaaaa tattattttt gcggtaattt
    35401 tttgcgccct aaaaccacta tattttgtgg agtatttcgt atgcgtcttg aaaaaattaa
    35461 tgttttatac tgcgtgctgg ccgtgtattg tgtatgcttt atttttcgca tatatgagta
    35521 ttttgtgctt cgtaccgatc agagtttttg gggtgaagcc ttcgttcata agctgatcgg
    35581 tataggaatt ttagggttgg tgatgcagtc ctgctctctt ggagcccgca gcattggatt
    35641 tacccgtgag cacataatgc gccctatcct tgccgggctg ggtttcggcg cagtagtttt
    35701 cgcgattgcc tatgccgctg agatagcgct tttaccgccc accgaatttc gctccctcga
    35761 cgtttatgtg agcacttacg cggtcagcag caatacgggg catcagacag cgctcatatt
    35821 ctttgtgatc tgtctggcgg ggaacatgat caacgtggtc atggaagaag gagtttttcg
    35881 cgggcttttt cagaaacttc tgggattccg ttactcgttt atgggtgctg cagtcatttc
    35941 ttcggcgctc tttggcctgt ggcatgtgat cgctcccgta cggaactata cggacggaac
    36001 ctcaagcttg ggtggagcgg tcatgaatgc tctgatcctg atgctgacat cagccgtggt
    36061 cggatttaaa tttgcgctga tgacgcgcct gacaggcagc ctctatatgg cgatggcaaa
    36121 ccactgtgca aataatgtga tcgtgaatct tgtgcatgta acgtcggttt ccggggagga
    36181 tacgctgatg ttcgtgcgga tctccatagc gcaagggcta tcatttcttg tggtggcagt
    36241 atggtacctg gtggcctcac gccgcgggag tcttcctgcg gcagggattg aggtggcgcc
    36301 cgcgtcacat ccgcagccgt gaaatttctg acgttttcga gcgcatatct acccccccat
    36361 aggcgtataa aaggctcttt ctgaataaag cgtagttttc cgccgcttct cttcaaaaag
    36421 agccttttta cacccgacat atacccggga tttcagccaa cgctagtgcg tgaaaccgtt
    36481 aataataccc atgccgaagt agatgacgaa cactgcggac accacgtaca tgagccagtg
    36541 cacctcgcgc ccgcggccct gcaccaggcg gataaaggcg taggagacga accctgcacc
    36601 aataccgtta gcgatcgagt acgacagcgg catgaaaata atggtcataa acgccgggat
    36661 gcccaggccc cagtcctgcc agtcgatatg cacggcttgg cgcaccatca ggaacccaac
    36721 aaccaccagg gcgggggcga ccgcctcaaa gggaacaatc gtcaccagcg gcgaggcgat
    36781 aatcgccacc aggaacagca caccggtgac aatattcgcc agacccgtgc gggcaccctc
    36841 accaataccg gttgccgact ccacaaaaat ctggttcgca gagccggatg cgccgccgcc
    36901 gaccacggaa ccgaccgcat ccacgagcag cacctcgtta atgttctcga ccttgccgtc
    36961 cttatcaatg gtgcccgctt cggttgctaa gcccaccgaa acgcccatgg catcaaagaa
    37021 gaccgagagc agaatagcga acaccagcaa ggatgcaccc agcacgccga tagcgccgaa
    37081 cgcgccgaat cgtgcagacc cgataagcga gaaatcgggg gctgagaagg aaaaattatt
    37141 gagcgcggga acgttgagcg accagccggt cgggttccct ttgctgctgc caatatggaa
    37201 aacagcctct aggatgatcg ccagtacggt agatgccacc acgccaatga ggatagcgcc
    37261 gcgcacattg cgaataaaca gggcgatggt gaggaaaagg ccgaaaataa acacgagagt
    37321 aggccagcca agtaggtgac cgcccacccc gagcgagacg ggaacggtgg ttcctgcggc
    37381 atccggcatg cggcggataa tcccggaatc aaccagcccg ataaaggcga taaagaagcc
    37441 gattcccgcc acaatcgcgg ttttgaggct ctcggggacc gcctcgaaaa cggcggtgcg
    37501 gaagccagtg agcaccagca cggtcataat aagaccggcg ataatcacca gccccataat
    37561 atctgcccac gtcagtccgg gagtggttgc gatcgtggac gccagcagtg cattcacacc
    37621 cagccccgcc gccatcgcga aaggttgctt ggctataaca cccatgagga tggtcattac
    37681 gccggcgacg agcgcggtga ccgcggcgac ctgcggcacg ccaagggtat ttcccgccga
    37741 gtctgcgccg gtgccgatca ccagggggtt gaggacgacg atataactca tagcgaagaa
    37801 cgcggcgaga ccgccacgaa tctcggctga aatagatgag cctcgttcag tgattttgaa
    37861 gtaacggtcc agtgcgccgc ccgatgcgtt gggcttgtgt gcctggggag ccgcggtgtt
    37921 ctcagaagac atttcgttga atccgtagat actctcgtgg gacgtgggcg cgggtttgcg
    37981 ccacaataag aaaagcgccg aaccccggcg ggattcagcg ctggtgttac caccctattc
    38041 taggtgtttt gtttttctcc cgcatccacc tgccgaaaag ccgccggggc gcctaagctc
    38101 tgtgacggac tttccggcag atggaatgct gggaagctgc ctttacccgt gggtgaaacc
    38161 gttaatgagt ccggtgctga agaacaccag gaaaacagcc gataccacgt acatgagcca
    38221 gtgcacctcg cgcccgcgac cctgcaccag gcggatgaag acgtaggaga tgaaccctgc
    38281 accaataccg tcggcaatgg agtaggcgaa cggcatgaaa ataatggtca taaacgccgg
    38341 gatacccagg ccccaatcct gccagtcgat atgcacggcc tggcggatca tgaggaaccc
    38401 cacgaaaacc atggcggggg cgaccgcctc gaaggggacg atggtcacca ggggagagag
    38461 gaagaccgcg cccacaaaga gcgcgccggt gaccacgttc gccaggcccg tgcgggcgcc
    38521 agcaccaata ccggttgccg attccacaaa aatctggttg gccgagctgg aggtgccacc
    38581 gcccgcaact gagccgagcg catccaccag cagcacacgg tcgatgttct caattttgcc
    38641 gtctttatca atggtgccag cttcggtggc taggcccacg gtggtgccca ttgcgtcgaa
    38701 gaacgccgag atgaggatgg tgaagaccag catcgtggcg gccataccgc cgatagtgcc
    38761 gaacgccccg aacatatctg ctgagaacag cagcgaaaca tcgggtaggg cgctgccgcc
    38821 gccccatgcg ggtacgttca gtgaccagcc ggtcgggttg tctttgctgc tgccaatgtg
    38881 gaaaacggct tctaggatta ttgacagcac ggtggaggca agcacaccgt ataggatggc
    38941 cccgcgtact ttccgaataa atagggcaat ggtgaggaac aacccgacaa ggaacaccac
    39001 ggtgggccag ccaagcaggt gcccgcccac gccgaaggtg acggggacgg tggtgtgcgc
    39061 ggcgtctacg gtgcggcgga taatacctgc gttgaccagc ccgataaagg cgataaagaa
    39121 gccgataccc accacaattg cggttttgag gctctcgggg accgcctcaa agacggcggt
    39181 gcggaagccg gtcagcacga gggcagtcat gagcacaccc gcccacacga ccagccccat
    39241 aatttgcggc caggtgaggt tgggggtgct gaggatagtg gttgccagta gtgcgttcac
    39301 gcccagtcct gccgccattg cgaaaggctg tttcgcgtag atgcccatgg cgatcgtcat
    39361 gattccggcg atgagcgcgg taaccgcggc cacctgcggc acgccgagcg cgtggccgtt
    39421 ggcgtctttc acgaggccga taatgagggg gtttagtacc acgatatagc tcatggcgaa
    39481 gaaggtcgct aagccgccgc gaatctcggc ggagatagtt gagcctcgtt ctgtaatttt
    39541 aaagtaacgg tccagggcgc cctgcgttgt gcgggtttgg ggtgcctggg gagccgcggt
    39601 gttctcagaa gacatttcgt tgaatccgta gatactctcg tagggtgcgt gcccaccggt
    39661 cgggggcgcg cataagaaaa gcgtcagccg tgcggggcgt gacgctcttg ttacctcatt
    39721 attctagggg gtagcagcgc gtgtgcgcta gttgcttgaa gaggggcggt agtacagcct
    39781 gtgagcgggc gcgcggtgga ggttttgggc tttaccgcag tggggtagtg agggtgaggc
    39841 ggggcctggg ctggctggta agatgaggaa taccttaact tccgtattgg tagggctact
    39901 accgagaatt tgagaggtga attgtgagcg agtatcctcc cgctgagtct ttgcctgtgc
    39961 gccagcgtgc cgtggttgct actgaacgcc cagcccgtta tgtgaaacag ctaggttcgc
    40021 atatgggccg taagattgat accgccgagc tgccgggcgg tctgcggctg acgtttaacc
    40081 gtgatggtat ttttcgtggc tatggcgatc tgctgattga tgaagctaat aacgccctca
    40141 ttatggaggt gcgtgctgag gatgaggaga aggccactaa tattgcgggt gtgctggatc
    40201 gccacctggt gcgctttggc gaacgtgacg agctggtggt tgagttccga agggtgtagg
    40261 cagacgttct atatactgcg gcacctccgt gggaaaaatg agggtggata ccccagatat
    40321 tttccctagt gcacttcgca ttcgctattt tctttgcggt gctctactgt gtggtggctg
    40381 aatattggcc caagattaag ctctggcagg gtgtggcttt cggcattgtg cttgatattc
    40441 ttttccacgt catcattatg cccgcaatgg gagttgtgcc cgccccgtgg aaccagcctt
    40501 ttggggagca cttctctgag ttctttgggc acatcctctg gttgtggtcg attgagctgg
    40561 tccgccgcga cctgcgtaac cgcatcaccg gtgaacccga tgcagagtac ccggtgactg
    40621 cccgctaaat cactgagtgt atcgtaaccg gtatacggct gtgccccgca tgagcgtctc
    40681 atgcggggca cagccgtatt gccatatata aggaataaaa atatatgagc tattgctcgc
    40741 tttccctctt tttagcccat cctaaccgct gtgcccggta gaatgaacga ggactaaaaa
    40801 gagagctcgc cgccgcacca gcctgaaccg tgtaccgggg cgaactttga aaggaaaaaa
    40861 tacgtgtctg aagctacccg ccccctgcgc gtcgctgtta ttggcgcagg ccccgctggc
    40921 atttacgccg ctgacctcat caccaaatct gaggaagtac gctctggagc cgttgaggtt
    40981 tctatcgata tttttgatcg ttaccccgct cccttcgggc tgattcgtta cggtgtggcg
    41041 cccgatcacc cgcgtattaa gggcattatt accgccctgc acaaggtgct tgaccgcggt
    41101 gatattcgat tcttcggcaa tgtcgaatac ggtaaggatt tgaaccttgc cgacctgcgc
    41161 gagcactacg acgccattat cttcgcgact ggcgctattc acgatgcacc tctacccatt
    41221 aagggcatcg acctggatgg ttcctatggt gccgccgatt tcgtctcgtg gtatgacggt
    41281 caccccgatt acccgcgcac ctggccgctg aacgcgaagg aaatcgcggt gcttggtaac
    41341 ggcaacgtgg cgttggatat tgcgcgtgtg ctctctaagc acgccgatga tctgcttgtc
    41401 accgaaattc ccgagaatgt gtacgaaggg ctgaaatctt cgcccgtgac cgatgtgcac
    41461 gtctttggcc gccgcggccc cgcgcagatc aagttcaccc ccttggagct gcgcgagctt
    41521 tcgcactccc gcgatgtcga tattgtgctc tacgaagagg acttcgagtt cgatgaggct
    41581 tcggatgagg ctattcagac gaataaccag gtgaagacca tgatgaagac cctcaccacc
    41641 tggcttaccg accaggagga gggcgagcag accgcatcgc gccgcctgca cctgcacttc
    41701 ctgcagtccc cgcacgagat tctgggtgag gacggcaagg ttgtgggcat ccgcatggaa
    41761 cgcaataagc ttgacggtaa gggcggtatc gagggcaccg gcgagttcgt ggactacccc
    41821 gtgcaggccg tgtaccgcgc gatcggttac ttcggatctg agctgcctga ggttggctat
    41881 gacgctgata agggcgtgat tacta
//
