LOCUS       NZ_LR134263            22550 bp    DNA     circular CON 05-APR-2024
DEFINITION  Staphylococcus delphini strain NCTC12225 chromosome 1, complete
            sequence.
ACCESSION   NZ_LR134263
VERSION     NZ_LR134263.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus delphini
  ORGANISM  Staphylococcus delphini
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus; Staphylococcus intermedius group.
REFERENCE   1  (bases 1 to 2798161)
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (18-DEC-2018) WTSI, Pathogen Informatics, Wellcome Trust
            Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900636325.1-RS_2024_04_05
            Annotation Date                   :: 04/05/2024 03:36:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,651
            CDSs (total)                      :: 2,569
            Genes (coding)                    :: 2,507
            CDSs (with protein)               :: 2,507
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 22 of 62
            Pseudo Genes (incomplete)         :: 40 of 62
            Pseudo Genes (internal stop)      :: 16 of 62
            Pseudo Genes (multiple problems)  :: 13 of 62
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:43:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2470768
            Orig. end                         :: 2493318
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR134263.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22550
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="7"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22550
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22550
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12550](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12550)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            complement(103..750)
                     /locus_tag="EL101_RS11645"
                     /old_locus_tag="NCTC12225_02397"
     CDS             complement(103..750)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738248.1"
                     /locus_tag="EL101_RS11645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02397"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_096540368.1"
                     /transl_table=11
                     /translation="MKKLVMINIVTIIVLIIIGVVGFYFYNQSVNYIKTDNAQVDGDQI
                     KIASPASGKISSLDVREGDTLKKGDTVAKVQGASQGEAPQTMTITMPKAGTIAKLDGQE
                     DGIAQAGQPIAYAYDLDDLYITANIDETEVKDVQNGQDVDVTIDGQDAKVKGKVDQIGH
                     ATASSFSLMPSSNSDGNYTKVTQVVPVKIKLNSQPSNGVVPGMNAEVSIHKN"
     gene            877..1440
                     /locus_tag="EL101_RS11650"
                     /old_locus_tag="NCTC12225_02398"
     CDS             877..1440
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614699.1"
                     /locus_tag="EL101_RS11650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02398"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_096597738.1"
                     /transl_table=11
                     /translation="MGKTKLKARRRIVRAMIELLKTEPLDAITIKEICAESGVHRSTFY
                     AQFEDKYQLFDVLTTYHMAKYEKLILYTSNVIESYPLEEAKARIIKTFRLLFKYMKRHQ
                     TFFMTIIVTQPQLKAIHQYLQFTRDAYEKLLNQLPQLQQSKYFINYTIGGELALIYSWL
                     MQGCQESPDDMAQILYSNIIKMGR"
     gene            1542..2711
                     /locus_tag="EL101_RS11655"
                     /old_locus_tag="NCTC12225_02399"
     CDS             1542..2711
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166302.1"
                     /locus_tag="EL101_RS11655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02399"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_096597740.1"
                     /transl_table=11
                     /translation="MASKATKQRIIELDALRGISLFGILLMNILVFSFPYNHTRLDLAL
                     QGVNGFLFRLVSLFVIDSFYPIFSFLFGFSLMLIYKSTHQRGIAFKPVMLRRLLFLMMI
                     GLLHGYLLFSGDILLTYAVMGFGAMWLTQFSIKKLKKLAIILFGIKVVVWGLPFLIMGW
                     LTKAKLPLSGGDQAELQALVQAKTSPHYMDFFIYNAQDNFANLITTLTADWIDIFPYLL
                     IGMAAMKGNLVEWVKQHPAHATQIGSLFIIIGTGLKFIGAYIITNPGYMMFSFTIGGPL
                     FSVGIVLLFFRVMQYTAAQKLLKPFRYPGKMSLSVYLTQSIVCVLFFAGFGFGFYNQLP
                     LYQTYLFALALFFIQVVICYVYQRHFTQGPFEWLWRKVTYFGVKTMSSK"
     gene            complement(2936..3508)
                     /locus_tag="EL101_RS11660"
                     /old_locus_tag="NCTC12225_02400"
     CDS             complement(2936..3508)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728653.1"
                     /locus_tag="EL101_RS11660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02400"
                     /product="GNAT family protein"
                     /protein_id="WP_096597742.1"
                     /transl_table=11
                     /translation="MQHFRLAVNDDIDFVYPTLKDAPALYKVVDQNRDHLKIFLPWAET
                     MTSVEEEAAFMQQTLNLVAEGKALFFLIYKQDQLIGTIDLHAWNEKTRKAEVGYWLAKS
                     ANGQGITTAAVRKLCDIAFTDYHLNKLELRANVLNIGSNRVAEKVGFRFVGVKHEDERD
                     GDQFVSMNYYEYLKRDFDHVVDDTRYV"
     gene            3737..5188
                     /locus_tag="EL101_RS11665"
                     /old_locus_tag="NCTC12225_02401"
     CDS             3737..5188
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166304.1"
                     /locus_tag="EL101_RS11665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02401"
                     /product="APC family permease"
                     /protein_id="WP_096597744.1"
                     /transl_table=11
                     /translation="MKKKNQKPDRGDLQQNLSEKFVWAIAYGSCIGWGSFILPGDWIQS
                     SGPIAASIGIFIGALLMIVIAVSYGALVERFPVSGGGFAFSFLGFGRYVSFFSAWFLTF
                     GYICVVALNATAFSLLIKFLLPDVIEFGKLYTIAGWDVYITEILIASILLLVFMLIAIK
                     GASVSGSLQYYFCVAMVVVVVLLFIGSFFGSNYSLDNLKPYNGTHYGWFQAIIMIVAVA
                     PWAYVGFDNIPQTAEEFDFSPNKTFKLIVYSLLAASLTYILMILYTGWLSGGSSDLWLT
                     GSVTREAFGTIGLGVLSIAIIMGIFTGLNGFLLSSSRLLFSMGRSGIMPSLFSKLHKRY
                     KTPYVAIMFLVAITLIAPWLGRTALTWIVDMSSTGVSIAYLVTCLAAAKLFSFNKNSQT
                     YGPVYKVFAIIGSIFALIFLLLLLLPFSPASLSMPSYIALGGWTILGLVFFFIRFPKLR
                     RMDKDELTQLILDTRKRDVEKMIEE"
     gene            complement(5492..5854)
                     /locus_tag="EL101_RS11670"
                     /old_locus_tag="NCTC12225_02402"
     CDS             complement(5492..5854)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016424340.1"
                     /locus_tag="EL101_RS11670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02402"
                     /product="DUF423 domain-containing protein"
                     /protein_id="WP_096540378.1"
                     /transl_table=11
                     /translation="MKVFIILGALNALMAVGTGAFGAHALDGKLSEHYMSVWEKATTYQ
                     MYHGLGLILIGIIGGALNLNVGWAGWLMFFGIVFFSGSLYILSLTQVSVLGAITPIGGI
                     LFVISWLMLAIAAFKL"
     gene            complement(5882..6205)
                     /locus_tag="EL101_RS11675"
                     /old_locus_tag="NCTC12225_02403"
     CDS             complement(5882..6205)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219916.1"
                     /locus_tag="EL101_RS11675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02403"
                     /product="DUF5327 family protein"
                     /protein_id="WP_096597746.1"
                     /transl_table=11
                     /translation="MNKDKLIQLLEHELVQADAATTDAAFEKHMYAIHALTALYTGQET
                     STPSRSSSAVTPKKQASAQVTDEEIRMMGGKVSSSSATAQTTSDQRMVTDDEIGNGASI
                     FDF"
     gene            complement(6198..6875)
                     /locus_tag="EL101_RS11680"
                     /old_locus_tag="NCTC12225_02404"
     CDS             complement(6198..6875)
                     /EC_number="3.2.2.27"
                     /GO_function="GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019168994.1"
                     /locus_tag="EL101_RS11680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02404"
                     /product="uracil-DNA glycosylase"
                     /protein_id="WP_308446747.1"
                     /transl_table=11
                     /translation="MKKMDWSTIFHEIKEKHDFKAMHDFLEKEYTTQIVYPERKNIYQA
                     FDLTPFENVKVVILGQDPYHGPNQAHGLAFSVQPGAKFPPSLRNMYQELADDIGCQRTS
                     PHLQDWAREGVLLLNTVLTVRQGQAHSHKDIGWETFTNEIIQAISDHKKGVVFVLWGRP
                     AQQKERLIDTSRHYVIKSPHPSPLSAHRGFFGSKPYSKTNAYLEAQGLAPIHWCEQKEE
                     TYE"
     gene            7056..7886
                     /gene="thiD"
                     /locus_tag="EL101_RS11685"
                     /old_locus_tag="NCTC12225_02405"
     CDS             7056..7886
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /GO_function="GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185456.1"
                     /locus_tag="EL101_RS11685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02405"
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="WP_096597830.1"
                     /transl_table=11
                     /translation="MALKKVLTIAGSDTSAGAGMQADLKTFQELDTYGMVALAAIVTMD
                     KETWSHDVSPIPFDVFNKQLETVISVGPDAVKTGMLGSEEIIQRAGEAYTESGAKNFVV
                     DPVMVCKGENEVLNPGNTEAMIKYLLPKATVATPNLFEAGQLSGLGTLKSIEDMKKAAK
                     IIHEQGAQHVVIKGGKALDQDKSYDLYYDGNKFYQLTTDMFQQSYNHGAGCTFAAATTA
                     NLANGQTPKEAVINAKAFVASAIKNGWKMNDFVGPVDHGASNRVEQIEVEVTEI"
     misc_feature    8270..8283
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.41"
                     /tool="antismash"
     gene            8315..9292
                     /locus_tag="EL101_RS13730"
                     /old_locus_tag="NCTC12225_02406"
     CDS             8315..9292
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017416.4"
                     /locus_tag="EL101_RS13730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02406"
                     /product="transposase"
                     /protein_id="WP_338133660.1"
                     /transl_table=11
                     /translation="MYKNYNMSQLTLPLETEMSFPENDVVFVINKLVESIPQEAFNPYY
                     NQRGPSSYHPKMMLKIILYSYANSVFSGRRIEHLLKDSCRMMWLAQGQTPTYRTINRFR
                     VNPHMMEFLHILFVGLRAQLLEDQLITEDVIYIDGTKIEANANKYTFQWLANTKRFSQS
                     VIEKSTALYEQLVSEEIIPEIKRESGHELTSEELNQIETHLGHKNDALTSEIETTQDVE
                     TRKNLRKERSKVRQSKKAIQDFKDRKLKYDKQMEIYGDRKSYSKTDHDATFMRMKDDHM
                     RNGQLKPGYNLQIATNNQFVLAFGVYSYPDDTRTLEPFLKSIHK"
     misc_feature    complement(9297..9307)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            9657..9929
                     /locus_tag="EL101_RS13735"
     CDS             9657..9929
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /locus_tag="EL101_RS13735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_308446750.1"
                     /transl_table=11
                     /translation="MSWDYFKAFTNKQLSDPKTKHIYQKRKIDVESTFGNLKANLGFQR
                     LSVRNQSKVECELGIALIAVNIRKLAKTSAHFRSLIRKKPSNSKK"
     gene            complement(10001..12550)
                     /locus_tag="EL101_RS11700"
                     /old_locus_tag="NCTC12225_02408"
     CDS             complement(10001..12550)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="EL101_RS11700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02408"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_096597748.1"
                     /sec_met_domain="Pkinase (E-value: 1.2e-09, bitscore: 35.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.5e-14, bitscore:
                     50.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQDPKYSNHFRFSSYDTFFYKKGNIDDDYLFYDSMYLRNIHNVYH
                     KDPWTYIHYTSTLHTSIWKIHISATVKNLQTVLKIVANYCDKIKLNFKFNSTFNNFVLM
                     NSKEISRVSAGKFITVYIEELGDLEIHLKELSKCLDKFEGPYILTDLHYKNNIYLRYGE
                     YYPITLMNEKGVFENFIVKNKESLIKDVRKPYYQEYDFIKKPDFLEFLNEDTISILLSN
                     YSINDVLHFSSGGGVYIGYSKDKRTKVVIKEARNYTGLDYNLIYFSERLKNEYNLLLKL
                     SYTKNVPEVYGILEDNGNTYLIEEYINGVTLKEYILKYNPLMRPKSDKRINKSYFKNMF
                     EIMIQIKSIVQKFHTKDIVIGDLSFNNFIINEKSLEVKMIDLETCIELSDFREGHKTMI
                     TPGFNNTSKNPIENDRNKFDTLIVTSIFPLNNIMHYFDEKYCEILDIFRHITDDFPYVQ
                     RIINLSFGGIKSASKENSKESLYSYINLISNSIMAEFSNEEGVFFPADPHVYNTNKYSV
                     SHGLFGVLYSLYKINNENIVYINKIIDDKIIFKLFKCDNIPKGIFMGFSGICWVLFELG
                     YKEIGKQLFEEKVLYKISKDNGMFYGNAGMLMTSIKIYVETQDKNYLEYANYLASYMMK
                     DVNFNELLTGYGEGISGISLSLIYYYKITMDIKVLNTAIKYFDIEYNNMIKDKCYLGIK
                     RNFEKNDRIVNSPYIYDGIAGVGIVAIRLFLVTKDKKYLEIIEKIVLSCDYKITLFSGY
                     MRGMAGIISFLTDVIKYIKDEDLVLKATEIISQFETSMKLHIINKGEYKHFLGEQLYKA
                     SCDYSTGGAGIILQIYYNKNNKMMNNPNFLLDELIDI"
     gene            complement(12551..14158)
                     /locus_tag="EL101_RS11705"
                     /old_locus_tag="NCTC12225_02409"
     CDS             complement(12551..14158)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="EL101_RS11705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02409"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_096597750.1"
                     /transl_table=11
                     /translation="MKIKLLQPKLFLIYVFMLITALDGLVIPTLVAGIIRSVEIKSLSS
                     LIHYFTFGIIGYCTIRTGLYLWNLYQQKYILDFNHTYKGKMIRKYFSGNHASMRADLLS
                     FIINDFKFLETNYIKSLFLFIYCVSFSFISATYVLVIDYQLGLLFILFSTIPVITPKLY
                     KNKVKQSTDTWSSDSSQFVDRLNEYFSALTTIRLFNKQSFFQSALTNRLHHLEKSNYTV
                     QKNLYQSNWVTHLLSGVSSFVPLFIGGLFVIEGHLSLAALMAVYLASDRIVTPAVNAID
                     YYNKLRSSNTIVRKYDHFIASLTHENSDVQNISNRPVSTLLPIKFEDILHQYGDRIIFE
                     HVHLTINQGDHILLKGPSGSGKSTFFKLLLLLERPQKGQLVFNNKDSQQMHFIDLVHSI
                     HYFEQSPFIFNASILFNITLGESFDDDQLDNVIEQCHLSNFVQTHGLEYHTGVSGNRLS
                     GGQKMRIALARIMIRKPKFVLLDEFSAGLDKENADFIRGIIHQQIETVIEITHDESIES
                     NYYNKTYEIKNVKVTEVN"
     CDS             complement(14377..14493)
                     /gene="allorf_2485145_2485261"
                     /locus_tag="allorf_2485145_2485261"
                     /protein_id="allorf_2485145_2485261"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDKLLELQTLKILETFDYLENSCTSCGASSCNGPDPIH"
     CDS_motif       complement(14434..14493)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDKLLELQTLKILETFDYLE"
                     /locus_tag="allorf_2485145_2485261_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14377..14433)
                     /prepeptide="core"
                     /locus_tag="allorf_2485145_2485261_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-2.70"
                     /molecular_weight="1659.8"
                     /monoisotopic_mass="1658.7"
                     /core_sequence="NSCTSCGASSCNGPDPIH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDKLLELQTLKILETFDYLE"
                     /leader_location="[14433:14493](-)"
                     /alternative_weights="1677.8"
                     /alternative_weights="1695.8"
     misc_feature    complement(14385..14398)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: strong, score: 23.25"
                     /tool="antismash"
     gene            complement(15002..15268)
                     /locus_tag="EL101_RS11710"
                     /old_locus_tag="NCTC12225_02411"
     CDS             complement(15002..15268)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219918.1"
                     /locus_tag="EL101_RS11710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02411"
                     /product="hypothetical protein"
                     /protein_id="WP_240622734.1"
                     /transl_table=11
                     /translation="MMYFSTEDVQHYLALVNDTNPIHTDIVPGQLVVQRICVAAAVEPI
                     AVRYKNPIIVDERVTWYRDNMQIQVLGIDEQLKLVIAVEETNN"
     gene            complement(15265..15636)
                     /locus_tag="EL101_RS11715"
                     /old_locus_tag="NCTC12225_02412"
     CDS             complement(15265..15636)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614707.1"
                     /locus_tag="EL101_RS11715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02412"
                     /product="hypothetical protein"
                     /protein_id="WP_096597754.1"
                     /transl_table=11
                     /translation="MQHFLNVGDREVKDYCFDKSTVHRYQQFFNMPQTTTVPLLMTARV
                     WPLFSLFRTFKETAIELVATEIEAHHPLKVGVHYQVTMAVLKVQQIKSFQRYQMALSFE
                     QGETCHCRIIQTFVSRRGS"
     gene            complement(15605..16750)
                     /locus_tag="EL101_RS11720"
                     /old_locus_tag="NCTC12225_02413"
     CDS             complement(15605..16750)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006635 - fatty acid beta-oxidation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614708.1"
                     /locus_tag="EL101_RS11720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02413"
                     /product="thiolase family protein"
                     /protein_id="WP_096597756.1"
                     /transl_table=11
                     /translation="MTKAVIVAAKRTPIGVYGGQLQKWEPEHLLKPLFEHFEATLPCSL
                     NDLDDVILGNIVGKGGNIARKSLLEAGIDVSVPGLTVDRQCGSGLEAIHLASRLVESGA
                     GDFYIAGGVESTSRAPWKMEKPTSLYPMTPPTFYDRAPFAPAGQDPSMIEAADNVAEQY
                     RVSREEQDRFAVQSHQRASEAISAGIMSAEILPLMVKGQQMTQDESVKPHLQYERIARL
                     KPLREDGTVTVGNCCLKHDGACLVVVMSEQKARELGMSEGLMFVDYAIEGVDPHVLGIG
                     PVPAVQRILERQQRTIDQIDAVELNEAFSAQVLASARALNIQEAQLNRYGGAIAIGHPY
                     SASGAILVTRLFYMKDAQSTIATMGIGGGMGNAALFERWRP"
     gene            complement(16747..18096)
                     /locus_tag="EL101_RS11725"
                     /old_locus_tag="NCTC12225_02414"
     CDS             complement(16747..18096)
                     /NRPS_PKS="Domain: AMP-binding (7-351). E-value: 9.7e-42.
                     Score: 134.9. Matches aSDomain:
                     nrpspksdomains_EL101_RS11725_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728644.1"
                     /locus_tag="EL101_RS11725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02414"
                     /product="AMP-binding protein"
                     /protein_id="WP_096597758.1"
                     /sec_met_domain="AMP-binding (E-value: 3.4e-33, bitscore:
                     112.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKRLETYAVERPEHIAIRMDNVTLTYETLWQHVQKESKTLPANM
                     TCQNVMLTHTQTADFIVAYLAVLVRQGVPCVLGPQWSMEQRDALMRLHRITYIWDDGGL
                     KCTSYEPSHKAPTIPQCLHIGFTSGTTGLPKGFIRDLPSWIASFEVNDTLLDASTQTYM
                     ALGPYAHSLTLYVLIYALWNGKTFIGQDRYNMAKGLSYVAELQQTCALFLVPTMVYDGI
                     HLGQRSQWVRHIFISGDKLPARRHTQLQTVFPESTIDEFFGTSEASFISVNRNQTAPLD
                     SVGRLFPNVTVTLRERDDAGIGQLFVKSPMTFSGYLGEDAVNDWIATGDYARIENDVLY
                     LQGRVQDRLIIGGKNVYPAVIEQYLKQWPEIVDTVIVRRPHDKLGELAIALYIGPEQLD
                     VQAVRHWLSSRVSRYEIPSKFIRVTSLPYTASGKVSRKMAQMCYERGDYQ"
     aSDomain        complement(17044..18075)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EL101_RS11725_AMP-binding.1"
                     /evalue="9.70E-42"
                     /label="EL101_RS11725_AMP-binding.1"
                     /locus_tag="EL101_RS11725"
                     /protein_end="351"
                     /protein_start="7"
                     /score="134.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="YAVERPEHIAIRMDNVTLTYETLWQHVQKESKTLPANMTCQNVML
                     THTQTADFIVAYLAVLVRQGVPCVLGPQWSMEQRDALMRLHRITYIWDDGGLKCTSYEP
                     SHKAPTIPQCLHIGFTSGTTGLPKGFIRDLPSWIASFEVNDTLLDASTQTYMALGPYAH
                     SLTLYVLIYALWNGKTFIGQDRYNMAKGLSYVAELQQTCALFLVPTMVYDGIHLGQRSQ
                     WVRHIFISGDKLPARRHTQLQTVFPESTIDEFFGTSEASFISVNRNQTAPLDSVGRLFP
                     NVTVTLRERDDAGIGQLFVKSPMTFSGYLGEDAVNDWIATGDYARIENDVLYLQGRVQD
                     RLII"
     CDS_motif       complement(17686..17727)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EL101_RS11725_0001"
                     /evalue="5.30E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="EL101_RS11725"
                     /protein_end="137"
                     /protein_start="123"
                     /score="13.0"
                     /tool="antismash"
                     /translation="IGFTSGTTGLPKGF"
     gene            complement(18310..18996)
                     /locus_tag="EL101_RS11730"
                     /old_locus_tag="NCTC12225_02415"
     CDS             complement(18310..18996)
                     /EC_number="5.4.2.11"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501165.1"
                     /locus_tag="EL101_RS11730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02415"
                     /product="2,3-diphosphoglycerate-dependent phosphoglycerate
                     mutase"
                     /protein_id="WP_096597759.1"
                     /transl_table=11
                     /translation="MPKLILCRHGQSVWNAENLFTGWADVDLSEQGHNEAITSGKKLKE
                     QDIHIDIAFTSLLKRAIKTTFHLLNESNQLFVPVVKSWRLNERHYGGLQGLNKDEARQQ
                     FGEEQVHIWRRSYDTPPPAQDEAQRESYLKDRKYELLDRRVMPEAESLKDTLVRVIPYW
                     NDQISQELLAGKTVLVAAHGNSLRALIKYLEGVSDEDIIGYEIKTGAPLIYELSDDLKV
                     IDKYYL"
     gene            complement(19256..20113)
                     /locus_tag="EL101_RS11735"
                     /old_locus_tag="NCTC12225_02416"
     CDS             complement(19256..20113)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614719.1"
                     /locus_tag="EL101_RS11735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02416"
                     /product="oxidoreductase"
                     /protein_id="WP_096597761.1"
                     /transl_table=11
                     /translation="MKIAIIGPGAVGTAIASALDTLDVTLLGRQDKVMTFEERDTGERK
                     SIPVKALSSVTTPFDVVFIAVKTHQIDTILPQLKTITHAQSKVILAQNGSGLLPKLEGY
                     DAYQAVVYISGEKQEDKVRHDKDYRIQLKQDTFTEQLKAVISTTKLTLELEDNIEKAIW
                     FKLIFNLGMNTLTALSRDTARLLKDDRMLELCKNLLKEGLQVANAEGITYEDSFVDDVI
                     AAYRIFSDESATSMYYDTMNERVTEVEAIQGYIYRQGQKHQLHIPYIETTYTLLAHQNE
                     VRQR"
     misc_feature    20165..20178
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.69"
                     /tool="antismash"
     gene            complement(20326..20499)
                     /locus_tag="EL101_RS13300"
                     /old_locus_tag="NCTC12225_02417"
     CDS             complement(20326..20499)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166661.1"
                     /locus_tag="EL101_RS13300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02417"
                     /product="hypothetical protein"
                     /protein_id="WP_096597763.1"
                     /transl_table=11
                     /translation="MFLVELKCSHCNKKLTKDDEIMIKTKVSELKGITNLKSWATLQKI
                     YCLRCYNSKESV"
     misc_feature    20451..20468
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 20.69"
                     /tool="antismash"
     gene            complement(20618..21301)
                     /locus_tag="EL101_RS11740"
                     /old_locus_tag="NCTC12225_02418"
     CDS             complement(20618..21301)
                     /EC_number="1.5.1.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219923.1"
                     /locus_tag="EL101_RS11740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02418"
                     /product="flavin reductase family protein"
                     /protein_id="WP_096540399.1"
                     /transl_table=11
                     /translation="MEYSPKQGVRSHGLPHDPFKSSTVPRPIGWISTVSKDGKDNLAPY
                     SQYQNLTWDPPMVMFAANQSVLGNHERKDTVKNAEETGWFVWNMATYDLREAVNLSSKA
                     LPPEEDEFEFAGVTKEACIEAPGYRVKESPVHFECEYVQTIRIPTGDPVSTVDIVIGRV
                     AQVHIDDKVIMENGKLDIKSIRPIARLGYYDYTVVDQIFEMKAPAATKEELAGLEGRNF
                     DNQTE"
     misc_feature    21495..21509
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 24.11"
                     /tool="antismash"
     gene            complement(21600..22148)
                     /gene="hxlB"
                     /locus_tag="EL101_RS11745"
                     /old_locus_tag="NCTC12225_02419"
     CDS             complement(21600..22148)
                     /EC_number="5.3.1.27"
                     /GO_function="GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="hxlB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019169036.1"
                     /locus_tag="EL101_RS11745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12225_02419"
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="WP_096597765.1"
                     /transl_table=11
                     /translation="MAIQQQFERIRREIEQTLSQVDNQAIAQFEQVVSDAEAVFVTGKG
                     RSGFVANGFAMRLNQLDKKAHVVGESTTPSIQKGDVLVVISGSGSTTHLKLLADKAHEV
                     GATIVLVTTAADSKIGELANVTLILPAGTKYQAEGSEQPLGSLFEQSAQLMLDGVVLDF
                     MTAWNVDETTMQNNHANLE"
ORIGIN
        1 gatttcttcc ttctacctcg aatgatcgtc cagttcagta tgataatcac aataagagca
       61 attatggtgt aaatcatcat aaacatgtga tgaccccctc tcttaatttt tgtgaatact
      121 tacttcagcg ttcatgcctg gaacaacacc gttagaaggt tggctgttta atttgatttt
      181 aacaggcacc acttgtgtca cctttgtgta gttgccgtca ctattcgatg atggcattaa
      241 tgaaaagctt gaggcagttg catgaccgat ttgatcaact ttacctttta cttttgcgtc
      301 ttgaccatca atcgtcacat caacatcttg accattttga acgtctttta cttctgtttc
      361 gtcaatattt gctgtgatat ataagtcgtc gagatcataa gcataagcaa tcggttgacc
      421 tgcttgcgcg ataccgtctt cttgaccatc taattttgcg atagtcccag ctttaggcat
      481 cgtaatcgtc atcgtttgtg gcgcttcacc ttgacttgca ccttgtactt tcgcgacagt
      541 atcccctttt ttcaatgtgt cgccttcacg aacatctaag ctactaattt ttcctgacgc
      601 tgggctggca attttaattt ggtccccatc cacttgtgcg ttgtctgttt taatatagtt
      661 cacagattga ttgtagaaat aaaatcctac aacaccgatg ataattaaca cgataatcgt
      721 aacaatgtta atcatgacta atttcttcat ttttactact ccctttctca atcaattcaa
      781 cttctgtatt ataagataat tcacttttga aaaatacaga caatcattac aaatgtgtcg
      841 gattgaaatt tataatataa taatgatggt gataatatgg gaaaaacaaa gttaaaagca
      901 agacggcgca tcgtgagggc aatgattgaa ttgttaaaaa cggaacctct tgatgcgatt
      961 acaattaaag aaatttgtgc agagagtggc gttcatcgtt caacatttta cgcccagttt
     1021 gaagataaat atcaattgtt tgatgttttg acgacatatc atatggcaaa gtatgaaaag
     1081 cttattttgt atacgtcaaa tgtgattgag tcttacccgt tagaagaggc aaaagcgcgt
     1141 atcatcaaaa catttcgttt actgtttaaa tatatgaaac gccaccaaac ttttttcatg
     1201 accattatcg tgacacaacc gcaattaaaa gccattcatc aatatttaca atttacacgt
     1261 gatgcttatg aaaagctatt aaatcaactg ccgcaattgc aacaatccaa atattttatc
     1321 aactatacga ttggcggtga acttgcactc atttacagtt ggctcatgca aggttgccaa
     1381 gaatctcctg acgatatggc acaaatttta tactcaaata ttattaaaat gggaaggtag
     1441 tttcactgtt gttgatgtca caagtatgct atcctgcgat tcatacacct aagttctagc
     1501 tgagatgaac ctataaaaag agagaagcga ggttatccat tatggcatcc aaagctacga
     1561 agcaacgtat cattgaatta gatgcgctac gaggaatcag tttgttcggt attttactga
     1621 tgaatattct agtttttagt ttcccttata accatacacg tctagatctt gcactccaag
     1681 gcgtcaatgg ctttttattt cgactcgtat cgctatttgt catcgattct ttttatccta
     1741 ttttttcttt cttattcggc tttagtttaa tgttgattta taaaagtacg catcaacgtg
     1801 gcattgcttt caagcctgtt atgctacggc gactgctatt tttgatgatg ataggcttat
     1861 tacatggcta tttgttattt tcaggagaca ttttattgac gtacgccgtt atggggtttg
     1921 gcgcgatgtg gttgacccag ttctcgataa aaaagcttaa aaaacttgcc atcattttat
     1981 ttggcattaa agtagtcgtt tggggattgc cttttctcat tatgggatgg ctcacgaaag
     2041 caaaattacc tttaagtggg ggcgaccaag cagaattaca agcattagtc caagccaaaa
     2101 cgagtccaca ttacatggat ttcttcattt ataatgcaca agataacttc gctaacctca
     2161 tcactacatt gacggcagac tggatcgata tctttcctta tttattgata ggcatggctg
     2221 cgatgaaagg caacttagtc gaatgggtga aacaacatcc agcacacgcg acacaaatag
     2281 gcagtctctt tattattatc gggacggggc ttaagtttat cggggcttat atcatcacga
     2341 accctggtta tatgatgttt agttttacta taggcgggcc cttgttctct gtcggcatcg
     2401 tacttctctt tttccgcgtc atgcagtata cagcggctca aaagttactc aagccgtttc
     2461 gttatcctgg aaaaatgagc ttgtccgtct atttaactca atctattgtt tgcgtattat
     2521 tctttgctgg attcggtttt ggcttttaca atcaattgcc actttaccaa acttaccttt
     2581 ttgcgctcgc tttgtttttt atacaagtcg tcatatgtta tgtgtatcaa cgtcatttta
     2641 cacaggggcc gttcgaatgg ctgtggcgta aagtcacata tttcggcgtc aaaacgatgt
     2701 catcaaaata agcgcaaacg ttaaacaggc ctgttcgatc attcatagtc gctacgctat
     2761 caatgtgaac aggccctttt attggagaac tttttgaaaa tgaaaaacac aaaatgatat
     2821 gtttactgtc atatcttttg cttaccctta ctgtatcatg ttttgaatca ttttgggata
     2881 caaatattag aaatttattg attttttatg aattgtctca caaaagatgt aacatttaca
     2941 catatcgggt atcatctacc acatgatcaa aatcacgttt caaatattca taataattca
     3001 tactcacgaa ttggtcgcca tctctttcgt cttcatgttt gacaccaacg aaacgaaatc
     3061 ccactttttc tgccacacga ttactcccaa tattaagtac attcgcacgc aattctaatt
     3121 tattgaggtg ataatccgta aatgcaatat cgcataattt gcgtactgca gcggttgtta
     3181 tcccttgacc atttgcactt ttcgcaagcc agtaaccgac ttctgcctta cgtgtttttt
     3241 cattccaagc atgtaaatca atagtcccaa tgagttgatc ttgtttataa atcaagaaaa
     3301 atagcgcttt cccctctgca actaagttta acgtttgttg cataaatgcc gcttcttctt
     3361 ccacagaggt catcgtttca gcccatggta aaaatatttt gagatggtct cgattttgat
     3421 cgacaacttt ataaagcgct ggtgcatcct taagtgttgg gtaaacaaaa tcaatgtcgt
     3481 cattcacagc gagtctgaaa tgttgcatcc cactcacccc tttttagttt tttgattatt
     3541 atacacaaat acaacaatta aaacaatatg tcttcaaaca gtagttcaca agcatttaca
     3601 tcaatcgcaa tctataaaac gcattttttt aatgcaattt ttcaatattt aggttatcat
     3661 ttattttcca actgtcgaaa ttcgttgtta taaaaaaata aaacaggggt ataagaatat
     3721 tcaggggtga aaaataatga aaaaaaagaa tcaaaaacct gatcgtggtg atctccaaca
     3781 aaacctttca gaaaaatttg tttgggccat tgcttatggt tcatgtatcg gttggggttc
     3841 gttcatctta ccaggtgact ggattcaatc atccggacct attgccgcat caatcggtat
     3901 ctttatcggt gccttattaa tgattgttat cgcggtaagt tacggtgcat tagtggaacg
     3961 ctttcctgtg tcaggtggcg gctttgcatt tagcttttta ggattcgggc gttatgtcag
     4021 ctttttctca gcatggtttt taacgtttgg atacatatgt gtcgtcgcgt taaatgcgac
     4081 agcgttcagt ttattaatta agtttttact gccagatgtg attgaatttg gcaaacttta
     4141 tacgattgca ggttgggatg tctacattac tgaaatttta attgcatcta tccttttact
     4201 cgtttttatg ttgattgcga ttaaaggggc aagcgtttca ggttcattgc aatattattt
     4261 ctgtgttgcg atggtcgtgg tcgtcgtatt actttttatc ggatcattct ttggttctaa
     4321 ctattcatta gataatttaa aaccttataa tgggacacat tatggatggt tccaagcgat
     4381 tattatgatt gtcgcagtcg caccgtgggc ctacgtcggt ttcgataata tcccacaaac
     4441 tgcagaagaa tttgacttct caccgaataa aacatttaaa ttaatcgttt atagtttact
     4501 tgcagcgagc ttgacctata tcttaatgat tttatataca ggctggttgt caggtggtag
     4561 tagtgactta tggttgaccg gttctgtcac acgagaagca ttcggtacaa tcggacttgg
     4621 cgtactcagt attgcgatca ttatggggat ttttaccggt ttaaacggct tcttgttaag
     4681 ctcaagtcgt ctgttattct caatgggtcg ctcaggtatt atgccgtcgt tatttagtaa
     4741 attacacaaa agatataaaa cgccatacgt tgcgattatg ttcttggttg cgattacatt
     4801 gattgcacca tggttaggcc gtactgcatt aacatggatt gtcgatatgt catctacagg
     4861 ggtgtctatc gcctaccttg tgacatgtct tgcagccgcg aaattgttta gctttaataa
     4921 aaatagtcaa acatacggac cagtgtataa agtctttgcg attattggct caatttttgc
     4981 cttgatcttt ttactgttat tattgttacc attttcaccg gcgtcgttat ctatgccatc
     5041 ctacattgcg ttagggggtt ggacgattct cggattggtg ttcttcttta ttcgttttcc
     5101 aaaattgcgt cgtatggata aagatgagct gacacaattg attttggata cgagaaaacg
     5161 tgatgttgaa aaaatgatag aagaataatt gattttgaaa tgttgaaagc aagatgcaca
     5221 tcagattaag cgaaactgag ggcaagttta tgaaatcaat agcatcaatt tttcgtatct
     5281 cattctccct cattttccaa ctactttaaa atcaattaat cagtcaaaaa tatatgaatg
     5341 gattgaggct taaaattttt atgtcctaat ccattctttg tttttgtcgg tatcaacaat
     5401 gtgtaaatta agttgaatta cgcacactcc attttttcca acaaaaaaag acagacgttt
     5461 gcctgtcttt tccaacttga ttcgattgaa cttataattt aaaagctgcg atggcaagca
     5521 tgagccagct aatgacaaac aaaatgccac caattggcgt aattgcacca agcacgctca
     5581 cttgcgttaa ggataagata tacagtgaac cactaaagaa cacgataccg aaaaacatga
     5641 gccaacctgc ccagccgacg ttaaggttca gtgcaccacc gataatgcca atcagtatca
     5701 gacctaatcc atgatacatc tgatatgttg tcgctttttc ccatactgac atataatgtt
     5761 ctgataattt cccgtctaat gcatgcgcac cgaaagcccc tgtacccact gccattaaag
     5821 cgttcagtgc acctaaaata ataaatactt tcacaatatt tcctcctcat caaagtgacc
     5881 attaaaaatc aaaaattgaa gcaccattgc ctatttcatc atccgtcacc atacgttgat
     5941 cagatgtcgt ttgtgcggtt gcgctagaag atgatacttt accgcccatc attcgaatct
     6001 cttcatctgt cacttgtgcc gacgcttgtt ttttcggtgt gacggctgaa gatgaacgtg
     6061 atggtgtact tgtctcttgc cccgtataca gcgccgttaa agcatgaatg gcatacatat
     6121 gtttttcaaa agctgcatca gtcgtcgcgg cgtctgcttg aaccaattcg tgttccaaca
     6181 gttgaatcag tttgtcttta ttcatacgtt tcctcctttt gttcacacca atggattggc
     6241 gctaaacctt gtgcttcaag ataggcattg gttttggaat acggtttaga accaaaaaag
     6301 cctctatgtg ccgacaatgg acttggatgt ggtgatttaa tgacgtagtg gcgcgatgta
     6361 tcaatcaatc gttctttttg ttgtgccggt ctgccccaca atacaaagac gacacctttt
     6421 ttatgatcag atatcgcttg gatgatttca ttcgtaaatg tttcccagcc aatatcttta
     6481 tgtgaatgtg cttgaccttg acgtactgtc agcaccgtat tcaataacag cacaccttct
     6541 ctcgcccaat cttgtaaatg tggcgacgtc cgttgacaac cgatatcgtc agccaactct
     6601 tgatacatgt ttcgcaatga aggtggaaat ttcgcacccg gttgcactga aaatgctaaa
     6661 ccatgtgctt gattcggacc atgataagga tcttgtccta atattaccac tttgacattt
     6721 tcgaatggcg tgaggtcaaa agcttgataa atattttttc gctcggggta aacaatttgc
     6781 gtcgtatatt ctttttctaa aaagtcatgc atcgctttaa aatcatgctt ttctttaatt
     6841 tcatgaaata ttgttgacca atccatcttc ttcacctcag ccacatttta acataatttc
     6901 gcctcactca ccgctatgat tcaataaaca tttttatagc agcctttcaa cgcgcatgct
     6961 aaaatggtga acataagcat attgtagtgt acagcagtta ccatcctcat tatggtatga
     7021 tgtaacagat gtacaattga aggagtgaat gaatgatggc tttgaaaaaa gtattaacga
     7081 ttgcaggatc agacacaagt gcgggcgcgg gaatgcaagc cgatttaaaa acatttcaag
     7141 agttagacac gtacggtatg gttgcacttg cggcaattgt cacaatggat aaagaaactt
     7201 ggtcacatga tgtgagccct atcccatttg atgtgttcaa caagcaactt gaaacagtca
     7261 ttagcgtagg accggatgca gtcaaaacag gtatgctcgg tagcgaagaa atcatccaac
     7321 gtgccggaga agcatacaca gaatcaggcg caaaaaattt cgtagtagac cctgttatgg
     7381 tatgtaaagg tgaaaatgaa gtgcttaacc cgggaaatac tgaagcaatg attaagtatt
     7441 tattaccgaa agcaactgtt gcgacaccga acctttttga agcaggtcaa ctatcaggtt
     7501 taggtacgtt aaaatcaatt gaagatatga aaaaagcagc gaaaatcatt cacgagcaag
     7561 gtgcacaaca cgtggtgatt aaaggtggta aagcgttaga tcaagataaa tcatacgact
     7621 tatactatga tggcaacaaa ttctatcaat taacaacaga catgttccaa caaagttaca
     7681 accacggagc aggctgtaca tttgcggcgg cgacaacagc caacttagcg aatgggcaaa
     7741 caccaaaaga agccgtgatt aatgcgaaag cgttcgtagc ttctgccatt aaaaatggtt
     7801 ggaaaatgaa cgattttgtc ggtcctgtcg atcatggtgc gtcaaatcgt gttgaacaaa
     7861 ttgaagtaga agtgacagaa atttaatttt ctgagcatgc ggattcaaag atccacgggg
     7921 ttggtcgatc tacttctctc tactctactc tacaactaat cgagtaggag aatagccatt
     7981 aattgactac tcgtcctctc acaccaccga gcgtacggtt ccgtactcag cggttcaata
     8041 tcttgcgtaa gccaactctg caagctgggc taatggtatt aatccccact tgtagagttg
     8101 ttttgttgta agtacacgat gaacctcgtg cgtgttcgat aaccgccagt atttcttacg
     8161 aggatgggac ataacccccc cttgtttgct aaaaaagctc tgattagatg ttgaaaaaca
     8221 tttaatcaga gctttttaga tattacttaa aaaaataaag cacttcccgt ataattatta
     8281 ataaccacaa aaataataga caggggtgct ttatatgtac aaaaattata acatgtctca
     8341 acttacactt ccactagaaa ctgagatgtc ttttccagaa aatgatgtcg tattcgtaat
     8401 caacaagctg gtagaatcta ttccccaaga agcttttaat ccatattata accaaagagg
     8461 tccttcatca taccacccaa aaatgatgtt gaaaattata ttgtatagtt atgccaattc
     8521 tgttttttca gggcgaagaa tcgagcacct cttaaaagat agttgccgaa tgatgtggct
     8581 tgcgcaaggt caaaccccaa cttatagaac aatcaatcgc tttagagtga atccccatat
     8641 gatggaattt ctacatattt tattcgtcgg tttaagagca cagttattag aagatcaact
     8701 cattacagag gatgtcattt atattgatgg cacaaaaata gaagccaatg cgaataagta
     8761 tacattccag tggctggcta atacgaagcg ttttagtcag tctgtcattg aaaaatcaac
     8821 ggcattatat gaacaactcg tttctgaaga gattattcct gaaatcaagc gtgaatctgg
     8881 acatgaatta acaagtgaag aactgaatca aatagagacg catttaggtc ataaaaatga
     8941 tgcgctcacg tctgaaattg aaacaactca agatgtagag acaagaaaaa accttagaaa
     9001 agaaagaagt aaagtgagac aaagtaagaa ggctatccaa gattttaagg accgtaaatt
     9061 aaaatatgac aagcaaatgg aaatttatgg cgacagaaaa agttattcta agactgatca
     9121 tgatgcgact ttcatgagaa tgaaagatga ccatatgaga aacggtcagt tgaaaccggg
     9181 ttacaatcta cagatagcta ccaataatca attcgtttta gcttttggtg tttatagtta
     9241 tccagatgat acaagaacgc tcgaaccatt tttaaaatca attcacaaat gatatggtga
     9301 cattccaaag tatatcgtgg cagatgcagg ttacggaagt gaatacaact ataccataat
     9361 actcgatgaa tttgagaaaa cacctttaat cacttatagt atgtacctca aagagaagca
     9421 gcgtaaatat aaaaacaatc cattgattac tgctaactgg gaatacaacg aggtaggaga
     9481 tgattatata tgtccgaata agaagacatt acatttccag agttacagaa agagaagaga
     9541 tggatacggt attcaaagag attttaaatg agatgcatgt taagagtgtg tgggctgtcc
     9601 attacgaagt caatgtatga agcaaagcac taatcccaag acaagtaaaa gtttatttgt
     9661 cttgggatta ttttaaagcc ttcacaaata agcagctttc agatccaaaa acgaagcaca
     9721 tttatcaaaa gagaaagata gatgttgaat caacttttgg aaatctgaag gctaatttgg
     9781 gttttcaaag attatcggtt cgcaatcaat caaaagttga gtgtgaactt ggcatcgcac
     9841 tcatagcagt aaatatacga aaactggcta aaaccagtgc tcattttcgt tcgctaataa
     9901 gaaaaaagcc atcaaattct aaaaaatgaa ttttgacggc tttttcttaa tggagctgaa
     9961 ggtctatgtc ccatccccct ttttattttt tgtcataaca tcaaatatct ataagttcat
    10021 ctaacaaaaa attaggattg ttcatcattt tattattttt attataatat atttgcaata
    10081 taatcccagc acctcctgtt gaataatcac aagacgcttt atataattgc tctccaagaa
    10141 aatgtttgta ttcaccctta tttattatgt gtaatttcat actagtttca aattgagaga
    10201 ttatttctgt tgcttttagt actaagtctt catcttttat gtactttatt acatctgtta
    10261 aaaaacttat tatgccggcc atacctctca tatatccgga aaataaagtg attttatagt
    10321 cacaagaaag tacaattttt tcaattattt ccaaatactt tttgtctttt gttactaaaa
    10381 acaatcgaat agcaacaata cctactccag ctataccatc atatatatat ggagaattaa
    10441 cgattctatc atttttctca aaatttcttt ttatacctaa ataacattta tcttttatca
    10501 tattattata ttctatatca aaatatttta ttgcagtatt tagcacctta atatccattg
    10561 ttattttata gtagtatatt aaagataaag aaataccaga tatgccttct ccatatcccg
    10621 taagcaactc gttaaagttt acatctttca tcatataaga agctaaataa tttgcatact
    10681 ctaaataatt tttatcctgt gtttcaacat atatttttat actggtcatt aacattcctg
    10741 catttccata aaacatgccg ttgtctttag atattttata aagtactttt tcttcaaata
    10801 attgtttgcc aatttcttta taacccaatt caaataaaac ccaacatata ccagaaaatc
    10861 ccataaaaat acctttaggt atattatcac atttgaataa tttgaatatt attttatcat
    10921 caattatttt attgatgtat actatgtttt cgttatttat tttatacaaa gaatataaaa
    10981 cgccaaaaag cccatgtgat acactatatt tatttgtatt atatacatga ggatcagcag
    11041 gaaaaaaaac tccttcttca tttgagaatt ctgccattat actattagaa atcaaattaa
    11101 tataactata taatgattct tttgaatttt ctttgcttgc actttttata ccaccaaaag
    11161 atagattgat aattctttgt acgtatggaa aatcatctgt tatatgtcta aaaatgtcta
    11221 atatttcaca atatttttca tcaaaataat gcattatatt attcaacgga aaaattgacg
    11281 ttacaattaa tgtatcaaat ttgtttctat cattttctat gggattcttt gatgtgttat
    11341 taaaacctgg tgttatcatc gtcttatggc cttctctaaa atcagataac tctatacatg
    11401 tctctaagtc tatcatttta acttctaatg atttttcatt aattatgaag ttattgaatg
    11461 ataagtctcc aatcactata tcttttgtat gaaacttttg gactatagac tttatttgta
    11521 tcataatttc aaacatattt ttaaagtaac tcttatttat tcttttatcg ctttttggcc
    11581 tcattaaagg attatatttt aaaatgtatt ctttcaaagt tactccatta atatactctt
    11641 ctatcaaata tgtgttgcca ttatcctcaa gtattccata aacttcagga acattttttg
    11701 tataggatag tttcaaaagc aaattatatt cgtttttcaa tctttcggaa aagtatatca
    11761 aattataatc taaccctgtg tagttacgag cttctttaat cacaacttta gtccttttat
    11821 ccttagaata acctatatag acaccacctc cacttgaaaa gtgtaataca tcattaatac
    11881 tatagttaga caatagaatt gatatggtgt cttcatttaa aaattctaaa aagtcaggtt
    11941 tctttataaa atcatattct tgataataag gttttcttac atctttaatt aatgattctt
    12001 tattttttac tataaaattt tcaaaaactc ctttttcatt catcagagta ataggatagt
    12061 attctccata tcttaaataa atgttatttt tataatgtaa gtctgtcaaa atatatggtc
    12121 cctcaaattt atctagacac ttagataatt ccttcaaatg aatttctaaa tctcctaatt
    12181 cttcaatata caccgttata aatttccctg cagaaactct agaaatttcc ttactattca
    12241 ttaatacaaa attattaaat gttgaattaa atttaaagtt taatttaatt ttatcacaat
    12301 aatttgcgac gattttcaga actgtttgta gatttttaac agttgccgat atatgtattt
    12361 tccatataga tgtatgcaaa gtagaagtat aatgtatata tgtccacgga tctttgtgat
    12421 acacattatg tatatttctt aaatacatag agtcataaaa taaataatca tcatcaatat
    12481 ttcctttctt ataaaaaaat gtgtcataag aactgaatct aaagtgattt gaatatttag
    12541 gatcttgcat ctaattcacc tctgttactt ttacattttt gatttcgtaa gtcttattgt
    12601 aatagtttga ttctatactt tcatcatgtg taatttcaat gactgtttca atttgttggt
    12661 gtatgatacc tcttataaaa tctgcatttt ctttatctaa tcctgcagaa aattcatcga
    12721 gtagcacaaa ctttggcttt ctaatcataa tacgtgccaa tgcaatcctc atcttttgcc
    12781 cccctgacaa acgatttcca ctgacacctg tatgatattc taatccatgt gtctgaacga
    12841 aattacttaa atgacattgc tcaattacat tatcgagttg atcatcatca aacgattcgc
    12901 ctaatgtaat gttaaatagt atggacgcat taaatataaa agggctttgt tcgaaataat
    12961 gaatagaatg aactaaatca ataaaatgca tttgttgtga atctttattg ttaaaaacta
    13021 attgtccttt ttgtggtcgc tcaagtaaca atagcagttt gaaaaaagta gatttgccac
    13081 ttcctgaagg tccttttaat aagatatgat ctccttgatt aatcgttaaa tgtacatgtt
    13141 caaatatgat gcggtcacca tattgatgca agatgtcctc aaactttata ggaagaagcg
    13201 tcgagaccgg tctatttgaa atattttgca cgtcactatt ctcatgagtg agtgaggcga
    13261 taaaatgatc atatttacga acaatcgtat ttgaggaccg cagtttatta taataatcta
    13321 tcgcattgac agctggcgta acgatgcgat cactcgccaa ataaactgcc attaaagcag
    13381 ccaaagaaag gtgaccttca attacgaaaa gtcctccgat aaataaaggg acaaacgaac
    13441 tcacaccaga taataagtgc gtcacccaat tcgactgata aagatttttc tgcacggtat
    13501 agttactttt ttctagatga tgcaatcgat ttgttaaagc agactggaag aaagactgtt
    13561 tattaaataa tcttatcgtt gtcaacgcac taaaatattc attgagacga tctacaaatt
    13621 gagaagaatc cgaagaccat gtatctgtgg actgtttgac tttattttta tagagcttag
    13681 gcgtaatcac agggatagta gaaaagagta taaataataa accaagctga taatcaatca
    13741 caaggacata cgtggcagag atgaaagaaa aactgacaca gtatataaat aaaaacaaag
    13801 atttgatata gttggtttca agaaatttga aatcattgat aataaaactt aataaatcgg
    13861 cacgcataga tgcatggttt cctgaaaagt attttcgtat catttttcct ttatatgtat
    13921 gattgaagtc tagaatatat ttttgttggt acagattcca taggtataaa ccagttcgaa
    13981 ttgtacagta accgatgata ccgaaagtaa aataatggat gagtgaggaa agacttttga
    14041 tttcaaccga acgaatgata ccagccacta gcgtcggaat caccaagcca tccaaagccg
    14101 taatcaacat aaaaacataa atgagaaata gtttgggttg tagtaattta attttcatct
    14161 ttatcaccta taaaataaaa cgataaaagc tttcgaacct tttatcgcat tattatttat
    14221 taatgacagc aaatataaat atatatatta tctaaataaa ttatattaat tttacacatg
    14281 atatttcact taaaatacaa taattagcta atacactaga tttttagtta caactctgcc
    14341 cgtttgttca tgtagttctt ccctttataa ataccattaa tgaattggat ccggtccatt
    14401 acacgatgag gctccacaag aagtacaact attttccaaa tagtcaaatg tttctaatat
    14461 ttttagtgtt tgtaattcta ataatttgtc catattaatc gtctcctttt aaatactatc
    14521 aatgaattgg atctggccca ttgcacgatg aagctccgca tgaggtacaa ctagcctcaa
    14581 aatagtcgaa cgtttccgat ttaatttgta ggcgttgtaa atttaaaagt gtaatcatat
    14641 gaataacctc ccaaaaagtg tatatactca cgattacatt ttatcacact taacaaccaa
    14701 agtaaacaga aaatttctga aattttgaaa agagtgaata tttcgttgct ttgagtgtat
    14761 tcgaaacata aaaaattcat caataattac tcaccaaaat tatattggcg cttgaaccta
    14821 tgaattatac cccaatttca gctttgcaaa tataataaag agaattatcc attctctcaa
    14881 taaagaaaga cttaccagat taagaacaaa agcgtcacag aagtcacata aaaacaggta
    14941 ctcaaaaagc gatgacgcat ctcctatgac aatagacatg ttcatcgcta tttttacggg
    15001 tttaattgtt tgtctcctct actgctatca cgagtttcag ctgttcatct attcccaaca
    15061 cttgaatttg catgttgtcg cgataccaag tgactcgttc atcgacaata atagggtttt
    15121 tataacgtac ggcgatgggt tcaactgctg ctgcgacaca tatccgttgc acaacgagtt
    15181 ggcctggcac aatgtccgta tggatcggat tcgtgtcatt cactagtgct aaatagtgct
    15241 gcacgtcttc tgttgaaaaa tacatcatga ccccctccga ctaacaaaag tttgtatgat
    15301 acgacaatgg catgtctcgc cttgctcgaa tgataacgcc atttgataac gttgaaatga
    15361 cttgatttgt tggactttta acactgccat cgtcacttga taatgcacgc ctacttttaa
    15421 agggtgatgc gcttcaattt ctgtcgctac aagttcaatt gccgtctctt taaacgttcg
    15481 aaatagcgaa aaaagcggcc atactcgtgc agtcattaat aaaggcacag tggtcgtctg
    15541 tggcatatta aaaaattgct gataacgatg gactgtactt ttgtcaaaac agtaatcttt
    15601 aacttcacgg tcgccaacgt tcaaaaagtg ctgcattacc catgcctcct ccaatgccca
    15661 ttgtcgcgat cgtactttgt gcatctttca tataaaacag acgggtcact aaaatcgcac
    15721 cactcgcact atacggatga ccgatcgcaa ttgcaccacc gtaacgattc aattgcgcct
    15781 cttgaatgtt caacgcacgt gcagacgcta gcacttgcgc actaaaagct tcattcaatt
    15841 ctacagcatc aatttggtct atcgttcgtt gttgtcgttc caaaatacgc tgtactgcgg
    15901 gtacaggacc gatgcctaat acatgcggat ccaccccttc aatcgcataa tccacaaaca
    15961 tcagaccttc tgacatacca agttcgcgtg ctttttgttc agacatgacg acaactagac
    16021 aagcgccgtc gtgtttgaga caacaattac cgactgtcac tgtcccatct tcacgcaatg
    16081 gctttaaccg tgcaatccgt tcatactgaa gatgcggctt aacactttca tcttgtgtca
    16141 tctgctgacc tttcaccatt aaaggcaata tttcagctga catgataccc gccgaaatcg
    16201 cttcactcgc acgttgatgg ctttgaaccg cgaaacgatc ttgctcttca cgtgatacac
    16261 gatactgttc tgccacgttg tctgccgctt caatcatact tggatcttga cctgccggcg
    16321 caaatggagc acggtcataa aatgtcggag gtgtcattgg atacagtgag gtcggctttt
    16381 ccattttcca aggtgcacgg ctcgtacttt cgacaccccc tgcaatataa aagtcccctg
    16441 cgccactttc aacgagtcga ctcgccaaat gaatcgcttc aaggcccgaa ccgcattgac
    16501 gatcaaccgt gagacctggg acagacacat ctatccctgc ctcgagcaaa ctttttcgcg
    16561 caatattgcc ccctttaccg acaatattac cgagaatgac atcatccaaa tcattgagcg
    16621 agcaaggtaa tgtcgcttca aaatgttcga ataacggttt caataaatgc tcaggctccc
    16681 atttttgaag ttggccacca tacactccaa ttggcgtccg ttttgctgca acgatgactg
    16741 ctttcgtcat tgataatcgc ccctttcata acacatttgt gccatttttc tcgaaacttt
    16801 tccactcgca gtatatggca atgatgtgac gcgaatgaat tttgaaggta tttcatatct
    16861 cgaaacacgt gatgacagcc agtgccgaac cgcttgaaca tccaactgct ccggaccgat
    16921 ataaagtgca atcgctaact cacctagctt atcgtgtgga cgtcgcacaa tgactgtatc
    16981 tacaatttca ggccattgct tgagatattg ttcaatcacg gcaggataca cattcttccc
    17041 accaataatt aagcggtctt gtacacgtcc ttgtaaatac aacacatcat tctcgatacg
    17101 ggcgtaatca cctgtcgcta tccaatcatt aacggcgtcc tcaccgagat aacctgaaaa
    17161 tgtcatcggg cttttcacaa acaattgtcc tattccggca tcatctcgtt cacgtaaagt
    17221 caccgtcaca tttggaaata gacgccccac agaatcgagt ggcgcagttt gatttcgatt
    17281 gacactaata aagctcgctt ccgacgtgcc gaaaaactca tcaatcgtac tttcaggaaa
    17341 taccgtttgg agttgtgtgt gacgacgagc tggcaatttg tcccctgaaa taaaaatgtg
    17401 acgtacccac tgtgatcgtt gtcctaaatg gatcccatcg tacaccattg taggtacgag
    17461 aaacaatgca cacgtttgtt gaagttctgc aacatacgac agaccttttg ccatattata
    17521 gcgatcttgc ccgataaacg ttttgccatt ccataacgca taaatcagca catacaacgt
    17581 taacgaatgg gcatacggac cgagcgccat atacgtctgt gtagaggcat cgagtaacgt
    17641 atcattcacc tcaaacgaag caatccatga cggtaaatct cttataaagc ctttcggtaa
    17701 acctgtcgta cctgacgtaa acccaatatg taagcattgc ggaatcgttg gcgctttatg
    17761 tgagggttca tatgaagtac acttcaaccc gccatcatcc catatataag ttatacggtg
    17821 taatctcatg agggcatccc gttgttccat tgaccattgt ggcccgagca cgcacggcac
    17881 accttgacgt acgagcactg ctaaataagc cacgataaag tccgccgttt gagtatgcgt
    17941 caacatcaca ttttgacacg tcatattcgc gggcaatgtt ttactttcct tttggacatg
    18001 ttgccacaac gtttcatagg tgagcgtcac attatccatc ctaattgcaa tatgttccgg
    18061 cctttctacg gcataggttt caagtcgctt taacaattcc aaacttcatc acactacttt
    18121 tacagttttg ctttatttta acatagcgcg cactttccac atatgtgaac gtcatttttg
    18181 tatctccaaa gttcaaatga tgtcatcacg tatcatgcaa aatgtaatga gaacgggtca
    18241 atatcgatgc atttccatat aaaaaggccg ggtcatcatg aaatgcccag ccttaaaatg
    18301 atacagttgt tataaataat atttatcaat gacttttaaa tcatctgaca gttcgtaaat
    18361 cagtggcgca cctgttttga tttcatagcc gatgatatct tcatccgata caccttctaa
    18421 atatttaatc aaagcacgta atgagttccc gtgtgccgcc acaagcactg ttttaccagc
    18481 taatagttct tgagaaattt ggtcgttcca atatgggatg acacgcacta aagtatcttt
    18541 caaactttca gcttcaggca ttacacgtct atctaataat tcgtatttgc gatcttttaa
    18601 atagctctcg cgttgtgctt catcttgtgc tggcggtggt gtatcgtaag agcgtctcca
    18661 aatatggact tgttcttcac caaattgctg acgtgcttca tctttattta atccttgtaa
    18721 accgccataa tgacgttcat tcaaacgcca cgatttaaca acgggtacaa agagttgatt
    18781 agactcattt aataaatgaa acgtggtctt aatcgcacgc ttcaataatg aggtaaatgc
    18841 gatatcaata tgaatgtctt gttctttcaa tttttttcct gatgtgatgg cttcgttgtg
    18901 accttgttcg gataaatcga cgtctgccca tcctgtaaat aagttttcag cattccagac
    18961 gctttgtccg tgtctacata aaataagttt tggcatgttt taccttcttt ctatgtcgtg
    19021 aacgccagtg ccgcaacatt tgttgatcaa aaaagacgtt cacgtactca tattgtatca
    19081 acaaatgcgc tttctttatt ttataaattg attataacaa gtttttcgct ctttttcata
    19141 ctttaaacat gataaaatat gaatatattg agtcatttgc tatcacatgg atttcaaaag
    19201 atttgattgt agtgaaatca tgttttccta tatttcacca taacagacta tatgtttatc
    19261 gctgtctgac ttcattttga tgcgccaaca atgtataggt cgtttcaata taaggaatgt
    19321 gaagttgatg cttttgacct tgtctataaa tatacccttg aatcgcttca acttctgtca
    19381 cacgttcgtt catcgtatca taatacatgc ttgtcgcact ttcgtcagag aagattcgat
    19441 atgctgcgat gacatcatct acaaatgaat cttcgtacgt aattccttct gcgttagcga
    19501 cttgcaaacc ttctttaagc aagtttttac ataattcaag catacggtcg tcttttaaca
    19561 ggcgcgcggt gtctcgactt aatgcagtta atgtattcat acctaggttg aaaatcaatt
    19621 taaaccaaat tgccttctca atattgtctt caagttctaa cgtgagcttt gtcgttgaaa
    19681 tgaccgcttt caattgttca gtaaacgtat cttgcttcaa ctgaatgcgg taatctttgt
    19741 catgtctcac tttatcctcc tgcttttcac cactaatgta tacgaccgct tgatacgcat
    19801 catagccctc taattttgga agtaagccgc taccattttg cgctaaaatc actttcgatt
    19861 gcgcgtgcgt gatggttttc agttgtggta aaattgtatc aatttgatgg gtcttcactg
    19921 caataaacac gacatcgaac ggcgtcgtta cagatgacaa cgctttgaca gggatacttt
    19981 tacgttctcc tgtatcgcgc tcttcaaatg tcatgacttt atcttgtctc cctaacaatg
    20041 ttacatctag cgtatccaat gccgaagcga tcgctgttcc taccgcaccg ggtccaatga
    20101 tggctatttt catctctttc atcctttcaa tcgcaaagtt taaacgctat ttctcgtcct
    20161 tttatagata taatccaata tattcttttt ttatttataa gtaaagcgag ttgattgtgc
    20221 atataaatga aaaaagaccg ggacatgatg atacgttttc ccagtcttta atgtaaaaat
    20281 tttaattctc ttttcaccac agaaactgaa cagcatactt ttctgctaca cgctttcttt
    20341 cgagttataa caacgcagac aatatatctt ttgcaatgtc gcccaagatt ttaaatttgt
    20401 gataccttta agttcagaga ctttggtttt aatcataatt tcatcatctt ttgttaactt
    20461 tttgttacaa tgactacatt tcaattcaac taaaaacatt gctgtcctcc tatgaaatct
    20521 tagaatcaaa cttaaacatt ccaaagattt tctattcttt tatttaaatg cgcctgtaag
    20581 aatgcaacga catcacttaa tggtatcgga agcacgctta ttcagtttga ttatcgaaat
    20641 tacgtccttc aagtcctgca agctcttctt tcgttgcggc tggggctttc atttcgaaaa
    20701 tttgatctac cacagtgtaa tcataataac cgaggcgtgc aatcggacga atagacttga
    20761 tatctaactt tccattctcc ataatcacct tgtcatcgat atgaacttgc gcgacacggc
    20821 caatgacaat atcgactgtt gatacaggat cccccgttgg aatgcgaatg gtttgtacat
    20881 actcacattc aaaatgtacg ggcgattctt taacacgata tccgggggct tcaatacatg
    20941 cttctttcgt gacgcctgca aactcaaact catcttcttc aggtggtaat gcttttgatg
    21001 acaagttcac cgcttctcgc aaatcatacg tggccatatt ccaaacaaac caacccgtct
    21061 cttccgcatt ctttactgta tctttgcgtt catgattgcc gagtacggat tgattcgccg
    21121 caaacataac cattggcggg tcccaagtta agttttgata ctgactataa ggtgccaaat
    21181 tatctttgcc atcttttgaa accgttgaaa tccaaccaat cggacgtggg actgtactac
    21241 tcttaaatgg atcgtgtggc aaaccgtgac ttctaacccc ttgttttggt gaatactcca
    21301 tcttattgcc tccttcatta ttgcctttac tttaatctaa caaattgtgt catccgttgc
    21361 taatacatgt ttcctattta attatcaagt agttctatta acagcatctg acgtacgtgg
    21421 aacagaacag tcccctatcc ccacttccaa catcgaggta tataggtttt gtcattcaat
    21481 tatcactcag accctggttt tcattttcaa tccttccgcg cacttcaaaa aagctagcct
    21541 ctacatctgt attgtagaaa ctagcttttc atcgacttta atttgtcatt tgattcaatt
    21601 tactctaaat tcgcatgatt gttttgcatc gttgtctcat cgacattcca tgcggtcata
    21661 aagtctaaca cgacaccatc taacatcaac tgtgcacttt gttcaaacaa gctgccgagt
    21721 ggttgttcag aaccttcagc ctgatatttc gtgccagctg gtagaatgag tgtcacgttt
    21781 gccaattcac caattttaga atccgctgct gtcgtcacca atacgatcgt ggcgccgact
    21841 tcatgcgctt tatcggctaa cagttttaaa tgtgttgtcg aacctgaacc ggaaatgaca
    21901 acaagcacat cccctttttg aatggacggt gtcgtcgatt ctccaacgac atgcgccttt
    21961 ttatcgagtt ggttcaatcg catcgcaaaa ccgttcgcga cgaatcctga acggcctttg
    22021 cctgtcacaa acaccgcttc tgcatcggat acaacttgtt cgaattgcgc aatcgcttga
    22081 ttatccactt gtgataacgt ctgttcaatc tcacggcgaa tccgttcaaa ctgctgttga
    22141 atagccatgt tacttacctt caatcgcttc acggatttgt ttcgccgctt cacgtggatc
    22201 gtcagcattt gcgataccgc cgcctacaat aattaaatct ggaccttcat ccgcaacttc
    22261 tttcacagtt tcaagtttaa taccaccagc gacagcaact ttagcgtttt taatcactga
    22321 tttgactttt cttaaactat ctaatggtga ttgcccttgt gcttgtaaat cataacctgt
    22381 atgcactgcg atatagtctg cacctaatgc gtcgatttct ttcgcacgtt tttctaaatc
    22441 ttgtaccgca attaagtcga caagcaattc tttaccatgc ttgtgcgctt cttccaccgc
    22501 atttttgatt gatgcatctt cagccacacc taaaattgtg accacatctg
//
