LOCUS       NZ_LR027842            22922 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  [Pseudopropionibacterium] massiliense strain Marseille-P6184, whole
            genome shotgun sequence.
ACCESSION   NZ_LR027842
VERSION     NZ_LR027842.1
KEYWORDS    WGS; RefSeq.
SOURCE      [Pseudopropionibacterium] massiliense
  ORGANISM  [Pseudopropionibacterium] massiliense
            Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
            Propionibacteriaceae; Arachnia.
REFERENCE   1
  CONSRTM   IHU Genomes
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2018) URMITE, IHU - Mediterranee Infection, 19-21
            Boulevard Jean Moulin, 13005 Marseille, France
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900607225.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:04:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,146
            CDSs (total)                      :: 3,092
            Genes (coding)                    :: 3,052
            CDSs (with protein)               :: 3,052
            Genes (RNA)                       :: 54
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 11 of 40
            Pseudo Genes (incomplete)         :: 35 of 40
            Pseudo Genes (internal stop)      :: 4 of 40
            Pseudo Genes (multiple problems)  :: 7 of 40
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:23:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2851584
            Orig. end                         :: 2874506
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR027842.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22922
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="10"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22922
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22922
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12922](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12922
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    463..477
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            complement(982..1956)
                     /locus_tag="E0E39_RS12700"
     CDS             complement(982..1956)
                     /EC_number="1.2.4.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014845456.1"
                     /locus_tag="E0E39_RS12700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="WP_130875075.1"
                     /transl_table=11
                     /translation="MSSMTIAKAINLGLRRALQADPKVLIAGEDVGKLGGVFRVTEGLQ
                     AEFGTNRVIDSPLAESGIIGTAVGLTMRGYRVVAEIQFDGFVFPAFDQLVTQVAKLHAR
                     TAGRQPMPMVVRIPYGGGIGAVEHHSESPEAYFCHTPGLKVVTPSNPHDAHWMIQQAVA
                     SPDPVIFLEPKRRYHVKGEVNTEQRPAPMHQAGILRQGTDATLVAWGPMVRTCLDAAAV
                     AAEEGTSVEVVDLRSLAPIDWVTLAASVRRTRRAVVVHEAPRTLGLGAEIAARLHEDLF
                     YDMESPVLRVTGYDIPYPPSRLEDEFLPSTDRILDALDRSLAW"
     gene            complement(1953..3032)
                     /gene="pdhA"
                     /locus_tag="E0E39_RS12705"
     CDS             complement(1953..3032)
                     /GO_component="GO:0045250 - cytosolic pyruvate
                     dehydrogenase complex [Evidence IEA]"
                     /GO_function="GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA]"
                     /GO_process="GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /gene="pdhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014845455.1"
                     /locus_tag="E0E39_RS12705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="WP_130875076.1"
                     /transl_table=11
                     /translation="MNHDMVQLLTPDGQRVENPGFSFGGTDDDLTQYLRDMVLARRFDT
                     EATALQRHGELGLWPPALGQEAAQVGSAHALGARDVVFPTYREHAVFLALGLPFQQILA
                     LFRGCDAGAWDQLDRFRNYQIIIGSQTLHATGYAMGLQLDGLVGNDDGDDAAVIAYHGD
                     GASSQGDVNEAYVFAASYNAPVVFFCQNNQWAISEPIALQSRIPLFQRARGFGFPGVQV
                     DGNDVLAVHAVTRWALERARKGEGPTFIEAFTYRMGAHTTSDDPTKYRPDEETAEWAGR
                     DPIARLTTHLKRQGVIDDAWLAALDADARDFGAEIRAAIPKLTDLTMDELFDNVYAENT
                     VALEAQRREYAEWAAGEQA"
     CDS             complement(3041..3169)
                     /gene="allorf_2854625_2854753"
                     /locus_tag="allorf_2854625_2854753"
                     /protein_id="allorf_2854625_2854753"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRGRGTASGGGWVEPTNLVGGIVGSRPSEETYAPVGYGCVGF"
     CDS_motif       complement(3107..3169)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRGRGTASGGGWVEPTNLVGG"
                     /locus_tag="allorf_2854625_2854753_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3041..3106)
                     /prepeptide="core"
                     /locus_tag="allorf_2854625_2854753_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.40"
                     /molecular_weight="2134.4"
                     /monoisotopic_mass="2133.0"
                     /core_sequence="IVGSRPSEETYAPVGYGCVGF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRGRGTASGGGWVEPTNLVGG"
                     /leader_location="[3106:3169](-)"
                     /alternative_weights="2152.4"
                     /alternative_weights="2170.4"
     gene            3408..3779
                     /locus_tag="E0E39_RS12710"
     CDS             3408..3779
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040449.3"
                     /locus_tag="E0E39_RS12710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6507 family protein"
                     /protein_id="WP_130875077.1"
                     /transl_table=11
                     /translation="MSQWKIVPKAVKAMLLEVSEQQKGLAATFSEEELGAVEAALSWCP
                     QVAGHIPVALKRVMETQKKNLHAVASHVNAGIVGVGNATISYEQAQQEMAGNFEREMFK
                     SAASGDFSYFEQYGYKGEE"
     gene            3783..5477
                     /locus_tag="E0E39_RS12715"
     CDS             3783..5477
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E0E39_RS12715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_165444789.1"
                     /transl_table=11
                     /translation="MPGENAPVDETGLINPDAFPCKPETLDPETINSAGDSSSSMGIDV
                     VSRTTAIRESWSRLPDIYESPEQEQVYGLMLKTTLPSFDIRAALVISGSAIQDYASTMV
                     TIKKDLQDLEEAAKKFREEAQAGYDEQVPDSRITIPRPAGVGWSGGAPPLKTEKTDWRR
                     HQHAVDKNNEFVAKYNAIYVKITQAVSECADRINKTDSTVCIPAPPAPTLEELEQMGPM
                     PWGAPGERQAKNCADSFNMGASRFFQEAWDNATRLAGFDEHGWSIGNTWNTIWGGAVGI
                     TDLGTSLVVSVAVAPFAAWGGYKPSEWERERMEVFVRAGASLVGFDLDAHWNGEDGWHK
                     WKSDPVATGTELGLGLFGKAAALKTLGKLGLLPKIPHPTTYLRNQIPKFATGLTNLSAS
                     VKEWMHKGNQKIFEGLDKLGEAADNLADEIRKRHGRQPAYAGPPGNGRRGITRNSDVVH
                     HTADPTPGTGKRSESQAKPRRAADDPRQDAGDHQTHGSDGNDPAALNSASGRTPEHLPP
                     GTNPAYYPDGLPHPDPHMGNEWTGDTGPGFDKPRTPATGDSDGGPGE"
     misc_feature    3957..3959
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5496..5909
                     /locus_tag="E0E39_RS12720"
     CDS             5496..5909
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF026984.4"
                     /locus_tag="E0E39_RS12720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Tox-REase-5 domain-containing protein"
                     /protein_id="WP_130875079.1"
                     /transl_table=11
                     /translation="MSKAAAEYQKHVTGVDHTLNANEKSFAIQEYIVRKSDGQSVDFDS
                     HVWRRDGNGNPQEVFLEAKNKYGWLFGKSKGLKPKRIQTMNDFYEQMARQLEVMPEGAK
                     LEWHFQEKIVADEVRRGLPLDLQGQVDIYFNPS"
     gene            6024..>6778
                     /locus_tag="E0E39_RS15850"
     CDS             6024..>6778
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E0E39_RS15850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_165444790.1"
                     /transl_table=11
                     /translation="MTNHDTRETPLEWHGFTAIWFNPDGKLRDFTPGVSRFLKDAEEIV
                     PDSRGNWFIIEENSTDAEVIASAISTRKVPGTRKLDGSPVYSEGVSGEAYLDGDPDNLE
                     SDNSVGRFRLHRAVDRAGQQTFDLILHRSTFPMLSDLVRSAAKHLHPDYISGSNIAFNQ
                     DMINARTASKRAVSLVGLVSWIRGLHPQELAGYPVTNVEEYEGGLYFEAISDQAGTTLA
                     QLADHLEHIGTRHTLGLPPERSSSVWPNRP"
     assembly_gap    6779..6879
                     /estimated_length=101
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(6970..8010)
                     /gene="purM"
                     /locus_tag="E0E39_RS12730"
     CDS             complement(6970..8010)
                     /EC_number="6.3.3.1"
                     /GO_function="GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="purM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014847503.1"
                     /locus_tag="E0E39_RS12730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="WP_130875081.1"
                     /transl_table=11
                     /translation="MSQSAYAAAGVDIEAGDRAVELMKASVARTRRPEVLGGLGGFAGF
                     FDASALKGYAHPVLATSTDGVGTKVAIAQALDRHDTIGFDLVGMLVDDLVVCGAEPLFV
                     TDYIACGRVVPERIAAIVSGIADACVAAGCSLVGGETAEHPGLLGPGEYDVAGATTGVV
                     ERDAILGADRVEAGDVVLAMASSGLHSNGYSLVRHVLLEQAGWRLEMHIDELGRTLGEE
                     LLTPTRVYALDVLALIREVECHAFSHITGGGLAANLARVIPAGRRARLERDSWTPPAIF
                     RLVQQAGRISQADIEATLNMGVGMVAILPETGVDAAVALLGSRGIDAWVLGRIETHDGP
                     GVAELV"
     gene            complement(8007..9470)
                     /gene="purF"
                     /locus_tag="E0E39_RS12735"
     CDS             complement(8007..9470)
                     /EC_number="2.4.2.14"
                     /GO_function="GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="purF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014847504.1"
                     /locus_tag="E0E39_RS12735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amidophosphoribosyltransferase"
                     /protein_id="WP_130875082.1"
                     /sec_met_domain="GATase_7 (E-value: 1.9e-15, bitscore:
                     54.4, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRPDGRLSLDLDPVDHGPKDACGVFGVFAPSEDVAQLTYYGLFA
                     LQHRGQESAGIAVSTGERITVFKDMGLVSQVFDEATLTSLRGRLGIGHTRYSTTGASVW
                     HNAQPTFRATRNGGLALAHNGNLTNTHELESWLRELDPGQRVPEKKTMDSTNDTSLVTA
                     LMSSFGTEPIEQVAMTVLPRLRGAFCLTFINETTLFAARDPQGVRPLVLGRLATGWVVA
                     SETAALDIVGASFVREVEPGEFIAIDEAGLRSRRFAEARPKGCLFEYVYLARPDTTIAG
                     RSVHATRVEIGRILAREHPVEADLVIPTPDSGTPSAVGYAEASGIPFGLGLVKNAYVGR
                     TFIQPSQTIRQLGIRLKLNPLKEVIAGKRLVVVDDSIVRGNTQRALVRMLREAGAKQVH
                     VRISSPPVEWPCFYGIDFATRAELIAPGLGVDEICRSLGADSLGYISLDALTEATHRPA
                     ADLCRACFDGRYPIAVPKGQAELLHLEEK"
     gene            9751..9915
                     /locus_tag="E0E39_RS15855"
     CDS             9751..9915
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E0E39_RS15855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_165444791.1"
                     /transl_table=11
                     /translation="MSDMNFLKEVADHELSQSEKTQAGGLWTVPGTRTIGAVCTVSWEC
                     HGFICGLFK"
     CDS_motif       9751..9825
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSDMNFLKEVADHELSQSEKTQAGG"
                     /locus_tag="E0E39_RS15855_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9826..9915
                     /prepeptide="core"
                     /locus_tag="E0E39_RS15855_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.30"
                     /molecular_weight="3092.6"
                     /monoisotopic_mass="3090.6"
                     /core_sequence="LWTVPGTRTIGAVCTVSWECHGFICGLFK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSDMNFLKEVADHELSQSEKTQAGG"
                     /leader_location="[9750:9825](+)"
                     /alternative_weights="3110.7"
                     /alternative_weights="3128.7"
     misc_feature    complement(9763..9777)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.67"
                     /tool="antismash"
     gene            10001..12922
                     /gene="lanM"
                     /locus_tag="E0E39_RS12740"
     CDS             10001..12922
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="E0E39_RS12740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_130875083.1"
                     /sec_met_domain="DUF4135 (E-value: 2.9e-56, bitscore:
                     188.8, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-37, bitscore:
                     126.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPTVYAAFPELNSTEVDALLHRNRAADELANLMSRTTGATAVTC
                     CPPELLQQALELLPTTDSPEPIPFFEATLAVAHEDLTCLLGRLRDHELLSHPRDTLRSV
                     LTATVSQMQNVLLRAQIHLASEHRLPDDQITCRTAEYTRLSTFLASKHGLRLFQERFPI
                     AVHIARNIVRRRTDFILQLLDHTASDLPFLHELGVGNDVKVSNISLGEGDSHHGKSVSI
                     LTFSDKSKVVYKPRSLANDQAFSLFQKHLQDITGNTKFLSCKVIDSGDHGWAEYVADNQ
                     ETRFDDPEALGNFAATIQLLGISDVHFENVRFRDGIPILTDTETLFSSVLESSRNPLGP
                     AARALSQLVTTSGFFPSPLMVPHKRNPIFVDVGVLGQRRPTGSGERSLTLRDPFTSDMR
                     IEPSGVSESLEESPPERFVAKDFIDAVCRSFRLTLTAALPDTPALLAFIRRTFADVTVR
                     SVAADTIRYSKALELATNAACLSDPELLLAALSRVGVFRDDVPAPLLASELRQLAQWDT
                     PAFVVAATGTDLLSGDEVVLPDAMTASPLDSITNALERIDENFIELSEWLIQVSFAPYY
                     EEDTEGTAFRFSNPVAPGTATPTRHSWDALNLGFVGGENEFTPTWLGARLSDTAHQYWY
                     PHELSIDAYAGSSGVALASAHVDGSRTRADDFFRQLVDKLQQADLLDPRFTRGALAGTE
                     SALWAADCYAQLVNDAALAGQARQLLRTLAVAPSNGYDIVAGDAGMVLLMTNLVANPLN
                     DSEQSLAALRIVSRRLADWVLSDRKPMSLTGYAHGTAGVGAALALAAPLVRSSEVDSVA
                     RAVLISLLDERDPRTGLWPIGTDHKFKGRGWCSGSPGLLLALAQIHSTGRFDDHHLEPT
                     ISLLVDATKRDCFGGNISLCHGDVGNLWILRHVASLTQDDHLAEDVTCASRRYLREVLP
                     RELTKPTRNSISHSLMGGTGGAALFEASMDETRPAVRSPLWLA"
     gene            12910..15045
                     /locus_tag="E0E39_RS12745"
     CDS             12910..15045
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="E0E39_RS12745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_130875084.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.4e-27, bitscore:
                     93.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARVKTSYQVTQSDCGIACAHMALRSAGSRLSLNALREAFAPGRD
                     GLTIPQLKQLIESQGATAKVYRAIVSTVHRLPTPAILLWEPSHYVVLERTVGKRHVIVD
                     PAGGRRVVGADEFAEHFAGLALCVTSPATRQETPDPSPWRSVLGIAWRRPYLLAAVLIG
                     AVVVGATTMALPNLTSGLLQQATTTPQASLTGMLVALAAGFFLIQLLNIAVTTFCATDI
                     GKRLGETVFHKLLNAPYSYFVVRPVGELLFRVGIVNRLEESLSTTLARGVVSSVIALVS
                     LGWIVVATPTIGMVVALILGVYVVAFEASRRVANRLTENLNSSESLANAVMVDSLNSIK
                     LVKSLGSEQQAFTSWVGHNTAAVRTRRTRALLSGTLTATVSTIQSFGPLSVLVLAISPL
                     GGAMALPAAVGLQMIAGVFFSQLSSLGSMAIEIGEANATVRRIDDILSAQEDSVFADVS
                     GKDFRFPLLAEAASFKFSRFAPQTINQVSIQCHEGERIAVVGATGSGKSTLVGLLAGLY
                     RPDRGSIRCGETELAEVAKPSFFDNVVYVPQDAPLRNTTLRDNLVWGDQSIDDSELIAA
                     LNQACFNLREQGLPMGLNTFLTNGGQNLSGGQRQRIAIARALLRHPRLLILDEATSALD
                     QETEAVVHRNLSAVGCSTITVTHRLETITGADRILVMDHGEIAEQGTFDDLFDRHGLFF
                     RMYNAYRTHHELQGATL"
     misc_feature    14563..14565
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15045..15935
                     /locus_tag="E0E39_RS12750"
     CDS             15045..15935
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="E0E39_RS12750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_130875085.1"
                     /transl_table=11
                     /translation="MLKIKHISKSYATIQAVADVSLTVQPGEIVGFVGPNGAGKSTTLR
                     MLTGMEEPDSGSCSINGQRIRDLTDPLTTFGALIDRQGVLKELTPMTAVQSLAAAYGIS
                     KNKGRTLLEQVGLGHALRRRVGTFSLGMKQRLGIALALLGEPQFLILDEPMNGLDPDGI
                     IWLRELLRNFARQDGGVLLSSHSLAEVEEMADTIIMVNHGSTIWSGSLQDIHTTSSCVV
                     VSTTENHRLLRELARRGLRAEMVDGVIHVFDCENEDIGRILHEGSFVPLTLATKRTSLE
                     DAYLELTAPDHRKAS"
     misc_feature    15903..15905
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16046..16795
                     /locus_tag="E0E39_RS12755"
     CDS             16046..16795
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E0E39_RS12755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="lantibiotic ABC transporter permease"
                     /protein_id="WP_130875086.1"
                     /transl_table=11
                     /translation="MQSHVFFGNRTLLLNLAAGLLAMTGLVAAVAFSVTNSFRSGHPLD
                     DPAFVQDIAVFGFPFAQIFLGVVAILFICSEWSSGFIYTTHSAIQRPLSFVVAKTIWPA
                     LTCAVGTVAMMVVVVPLESWLLAGTPYSISLLDAAVWRQIAALAFVTMSAVSFAAGIAL
                     ILRNSATALGLYIRIILIAPIIIGQIPVDTAREIAKWLPNNVFNFLTTNAPNVTATLNY
                     PLLIATAIAYPLAILTIGFLPLRRRVI"
     gene            complement(16851..18179)
                     /locus_tag="E0E39_RS12760"
     CDS             complement(16851..18179)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014847506.1"
                     /locus_tag="E0E39_RS12760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dipeptidase"
                     /protein_id="WP_130875087.1"
                     /transl_table=11
                     /translation="MTNLAWNVERVLPSAIADLHKLIAIPSISSMPEHDADVAACAETV
                     SGLFRDLGASEVKLLDGGGKPAVWANFPGPEGTPTVLLYAHYDVQPTGDAEAWTSPAFE
                     PTERDGRLYARGSADDKGGVALHVAALRVFDGKPPVGVKVFIEGEEEIGSPSMPTLLDR
                     YRDELAADVYVVADSVNWEVGKPSLTTSLRGVAACEVTVSTLAEGLHSGQFGGIVPDAL
                     TALCRLLATLHDDAGNVAIEGLVSGPGPDLDYPEDRLLEETGLLDGVSQLGDGSVVERM
                     WFKPSASVLAIDATPVAKASNTLVPSARAKVSVRLVPGQDPAAAAKALEEHLRSHAPWG
                     ARVEIDSEQVGAPSRIALEGERAEAARKAFRDAFGVEAVEIGCGGSIPIVAEFADRNSE
                     ALVLVTAVTDPNSRMHGIDESLDLGDFAKAALAETLLLNNLAG"
     gene            complement(18263..19129)
                     /locus_tag="E0E39_RS12765"
     CDS             complement(18263..19129)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014847507.1"
                     /locus_tag="E0E39_RS12765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_130875088.1"
                     /transl_table=11
                     /translation="MNDNVTLKGARWWKEVGWKHILAVVLMLYCIFPLLYVLSASLNPG
                     GTISGSSQLFRTVSAENYATLFGTNFPRWMLQSFVVSISTAIGTVLMAASAAYAFSRYR
                     FTGRRGGLTALMLVQMFPQMLAFVAIFLLLLMLRDVYPVLGLNSALGLIAVYLGGALGG
                     NTFLIYGFFNTIPKELDEAARIDGATHAQIFWGVIMRLVTPILVVVGLLSFVSSYGEFI
                     LAKVVLQRPEDYTLAVGMYVWASDERNAPWSLFAAGAVVAAIPIILLFMYLQKYIVAGL
                     TAGAVKG"
     gene            complement(19129..20700)
                     /locus_tag="E0E39_RS12770"
     CDS             complement(19129..20700)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014847508.1"
                     /locus_tag="E0E39_RS12770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_130875089.1"
                     /transl_table=11
                     /translation="MKERTDPAEPRLSHARDYTRPGFYAKLVLMALVNAFGLYGIMVSI
                     PQRQWLVLGFLAVTLLVADYVYFSKRAVPAKYLLPGLVFLLVYQVYVMGSTAWVAFTNY
                     GDGHNDSKQAAITQILKASDRRVEGTSTYPVTVVEKDGELGFAVVRDGHAEAGTQNTPL
                     AEVQGAVVAGTRVTEVPGWNVLSPPDVQARQKDVLELRVNLSDDPTQGWLRTDNASFAY
                     VAKSALTHDAAADTFTDPDGKIYHADESVGAYVASDGSQLTPGWRVFVGTRNFTEVFND
                     SRLTGPFLSITAWTFAFAILSVATTFALGLALAVIYNDKRVRGRTFYRAIFLLPYAFPA
                     FLAALTWKGMLNREFGIINQMLGGADIAWLSDGNLAKFAILGVNLWLGFPYMFLVSTGA
                     LQAIPAELTEAAIMDGAGAWRRFRSVTLPMLMVSLAPLLIASFAFNFNNFSLIYMLTGG
                     GPNYSGSPLLIGETDILISMVYAIAFESGGKQYGLASALSLIIFVVVGVIAWLGFRQTR
                     KLEEIM"
     gene            complement(20758..21966)
                     /locus_tag="E0E39_RS12775"
     CDS             complement(20758..21966)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014847509.1"
                     /locus_tag="E0E39_RS12775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="maltose ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_130875090.1"
                     /transl_table=11
                     /translation="MSKRLLALAATGLVLALTACGSASNTTSNSSSGGSQASGTLTVWT
                     DETRIEGFNAIGEAFQKATGVKLEVVQKPTDDVRTDFIAQAPSGAGPDLIVGANDWVGS
                     LVKNGVVAPVELGDKANGFSDAAKKAFTSDGTLYGVPYAVENIALVRNNALAKDTPATF
                     DELIAQGKQLTPDHPVLIQQGDKGDAYHLYPVQSSFGAPLFKPDTTEIGMKGEAGEKFA
                     AYIKTLTDEGVLSESIGGDQAKQAFLDGKSPYIITGPWWTGEFTKAGLDISVLPVPSAG
                     GQPSAPFIGVQGVYLSSYSKNALLANQFLDYMAGDEAQKILQEKGGRLPALKSAAAAVT
                     DPVLKGFETAGESGQPLPATITTMDAVWSHWGSAELSILRGEDPVSTWQQMISNVEDAL
                     AKG"
     misc_feature    complement(21993..22007)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    22043..22056
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.09"
                     /tool="antismash"
     misc_feature    complement(22043..22057)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.78"
                     /tool="antismash"
     misc_feature    22044..22057
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.06"
                     /tool="antismash"
     misc_feature    22044..22058
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 25.59"
                     /tool="antismash"
ORIGIN
        1 atcagcagcg gcgagacccg cagacccgcg aactcccgcc gcgccctgag ggtctcgacg
       61 aactccatcg tgccggtgac gtcggtggtc aaccactcgg tgacgtggac gtgggtgttc
      121 acggaacgca ccatcgcctc ggcggtgacc ttgcgcaccc ccttgatggg aacgcgacgt
      181 tccccgcgac cccccgggcc gcgcggcgac ccgaagccgt ggctccgcgg tcccgggtcc
      241 tggaaactgg cggcgtcgtt gacgaccctg ccctgcgcgg gctcctccct gacaccctcc
      301 cccgctgcac gggaccgttc gaagatccac gcggcctcga cgtcggcgcg ggtgatggtg
      361 ccctccggcc cggttcccgc gaccttcccg aggtcgaccc cgaggtcgcg agcgtacttg
      421 cgcaccggcg gtttggcccg cgcggactgc gggtcggagg ccagcaccaa tgtcgattcg
      481 gtgggagcgt cacccgtctc cggcaacgga tcaccgacgg gagcggcaac gacccggccc
      541 gcgggatcca cgtcgtcggg acgccgcgac ggctcacggg aggcgtagct ctcccccagc
      601 ccctggaggg cggcctccgc atcccgacta gtagtgcttc tgcggcggcg cctcgacctg
      661 gcggtttcgt cgcgcggccc gtagccgacg agggtcgggg gctcctcccc gccaccctcg
      721 acgccgtcct cgatctcgac gatggcggtg ccgacctcca ccgtgacccc ctccgccacc
      781 agcagcgacg tcacggtccc ggcgtagggc gagggcagct ccaccagcga cttggcggtc
      841 tcgatctcga cgagcacgtc gttgacgtcg acctcctgcc cggcggcgac ccgccaggcc
      901 acgatctcgg cctccgtgag accctcaccg gggtccggga gaaggaactg gcgtttcatc
      961 atcactcctt gtctcctgta ctcaccaggc gagggaacgg tcgagggcgt cgaggatgcg
     1021 gtcggtcgac ggcaggaact cgtcctccag gcgcgagggc gggtagggga tgtcgtagcc
     1081 ggtgacgcgc agcaccgggg attccatgtc gtagaacagg tcctcgtgga gacgggcggc
     1141 gatctccgcg cccaacccga gggtgcgggg tgcctcgtgg acgacgacgg cgcggcgggt
     1201 gcggcgcacg gaggcggcga gggtgaccca gtcgatgggc gcgagggagc ggaggtcgac
     1261 gacctccacc gaggtaccct cctcggcggc gacggcggcg gcgtccaggc aggtgcggac
     1321 catcggcccc caggcgacga gggtcgcgtc ggttccctgc cggaggatcc cggcctggtg
     1381 catgggggcg ggccgctgct cggtgttcac ctcgcccttg acgtggtaac ggcgtttggg
     1441 ttcgaggaag atcaccggat ccggggaggc gacggcctgc tggatcatcc agtgggcgtc
     1501 gtgcgggttg gagggggtga ccaccttcaa cccgggggtg tggcagaagt aggcctccgg
     1561 ggattcggag tggtgttcga cggccccgat gccgccgccg taggggatgc gcaccaccat
     1621 cggcatcggt tgccgcccgg cggtgcgggc gtgcagtttc gcgacctgcg tgacgagctg
     1681 gtcgaaggcg gggaagacga aaccgtcgaa ctggatctcg gccaccacgc ggtagccgcg
     1741 catcgtcagc ccgacggccg tgccgatgat tcctgattcc gccagcggcg agtcgatgac
     1801 ccggttggtt ccgaactccg cctggaggcc ttcggtgacg cggaacacgc cgccgagttt
     1861 cccgacgtcc tcgccggcga tcaggacctt cgggtcggcc tggagggcgc ggcgcagacc
     1921 caggttgatg gccttggcga tcgtcatact gctcatgcct gctcccctgc cgcccattcg
     1981 gcgtactcgc ggcgctgcgc ctcgagggcg acggtgttct cggcgtagac gttgtcgaac
     2041 agttcatcca tggtcaggtc cgtcagtttc gggatggcgg cgcggatctc ggcgccgaag
     2101 tcgcgggcgt cggcgtcgag agcggccagc caggcgtcgt cgatgacccc ctgccgtttc
     2161 aggtgggtgg tcaggcgggc gatggggtcg cggccggccc actcggcggt ttcctcgtcg
     2221 ggccggtact tggtggggtc gtcggaggtg gtgtgggcgc ccattcgata ggtgaacgcc
     2281 tcgatgaagg tgggcccctc gcccttgcgg gcgcgttcca gggcccagcg ggtgacggcg
     2341 tggacggcca gcacgtcgtt gccatccacc tgcaccccgg ggaatccgaa tccccgggcg
     2401 cgctggaaca gcgggatccg cgactgcaac gcgatgggtt cggagatcgc ccactggttg
     2461 ttctggcaga agaagacgac gggggcgttg tagctggccg cgaacacgta ggcctcgttg
     2521 acgtcgccct gggagctggc cccgtcgccg tggtaggcga tcacggccgc atcgtcgccg
     2581 tcgtcgttgc cgacgaggcc gtcgagctgc aaccccatgg cgtagccggt ggcgtggagg
     2641 gtctgggagc cgatgatgat ctggtagttg cggaaccggt cgagctggtc ccaggccccg
     2701 gcgtcgcagc cccggaacag ggccagaatc tgctgaaagg gcaggccgag agcgaggaag
     2761 acggcgtgtt cccggtaggt ggggaagacg acatcgcggg caccgagggc gtgggcggag
     2821 ccgacctgcg cggcctcctg cccgagggcg ggcggccaca aaccgagttc cccgtgccgt
     2881 tggagggccg tggcctcggt gtcgaaacgc cttgccagca ccatgtcccg caggtactgg
     2941 gtcaggtcgt cgtcggttcc cccgaaggag aacccggggt tctcgacgcg ctgcccgtcg
     3001 ggggtcagca actgcaccat gtcgtgattc atgacctctc ctaaaaacct acgcaaccgt
     3061 agcctacggg ggcgtaggtt tcctccgaag gtcgagaacc tacaattcct ccgacgagat
     3121 ttgttggttc cacccatccg cccccggaag ccgtcccgcg ccctcgcacg cgacacgagg
     3181 cgcgcgagtg tcatcttttt ggttgacgcg ggcccggtgc atgtcattcg ctcgcgggta
     3241 ttgctcgaag tcgggtcggt tctggccaag tcccggggcg ggacatctcg atccctcgta
     3301 cggcccgggg ttgcggatgc cggggttctt tcggtcgggt tctgtatccg ggggttcggc
     3361 tcggcgggca cgagtgtcgc cgttgaactg caggaaggga actgctgatg tcccagtgga
     3421 agatcgtacc caaggccgtg aaggcgatgc tgctggaggt ttccgagcag cagaagggcc
     3481 tggccgccac tttttccgag gaagagctcg gagccgtcga ggctgctctg tcgtggtgcc
     3541 cgcaggttgc cggacacatt ccggttgcgc tgaagcgggt gatggaaacc cagaagaaga
     3601 acctgcacgc ggtggcgtcg cacgtgaacg ccggaattgt gggggtggga aatgcaacga
     3661 tctcttacga gcaagcgcag caggagatgg caggcaactt cgagagggag atgttcaaat
     3721 ctgcggcatc cggagatttc tcgtatttcg agcaatacgg ctacaagggt gaggagtagg
     3781 acatgccggg cgagaatgcc ccagtggatg aaactggcct gataaaccca gacgcatttc
     3841 cctgcaagcc ggaaaccttg gatcccgaga cgatcaattc tgccggcgat tcctcgagtt
     3901 ccatgggcat cgatgtcgtt tcacggacga ccgcgatcag ggagtcgtgg tccaggttac
     3961 cggacatcta cgagtctccg gagcaggagc aggtgtatgg tttgatgctg aaaaccactc
     4021 ttccctcctt cgacatcagg gctgcactgg tgatatcggg atcggccatc caggattatg
     4081 ccagcacgat ggtcacgatc aaaaaggatc ttcaggacct ggaggaggct gcgaagaagt
     4141 tccgggagga ggctcaagcc gggtacgatg aacaggtgcc ggattcgaga atcacgattc
     4201 cgcggcctgc cggtgtgggg tggagtggcg gcgcgccgcc attgaagacg gagaagaccg
     4261 attggcgacg ccatcagcac gccgtcgaca agaacaacga gttcgtggcg aagtacaacg
     4321 cgatctacgt gaagatcacc caggccgtca gcgagtgcgc ggacaggatc aacaaaacgg
     4381 actcgacggt gtgcattccg gctcccccgg cccccaccct cgaagaactg gagcagatgg
     4441 gccccatgcc gtggggagcc cccggggaac gccaggcgaa gaactgcgct gattccttca
     4501 acatgggggc cagccggttc ttccaggaag cctgggacaa cgccacgcgc ctcgcgggtt
     4561 tcgacgagca cggctggagc atcgggaaca cgtggaacac gatctggggc ggtgcggtgg
     4621 gcatcaccga cctgggtacc tcgctggtcg tatccgttgc cgtggccccc ttcgccgcgt
     4681 ggggagggta caagcccagc gagtgggaac gcgaacgcat ggaggtcttc gtgcgcgccg
     4741 gggcgagctt ggtgggtttc gatctcgatg cccactggaa cggcgaggac ggctggcaca
     4801 agtggaagag cgatcccgtc gccaccggaa ccgagctggg cctcgggctc ttcgggaagg
     4861 ccgccgcctt gaaaaccttg ggcaagctcg gtctgcttcc caaaattccg cacccgacca
     4921 cgtatctgcg caaccagatc ccgaaattcg caaccggcct cacgaacctc agcgcatccg
     4981 tcaaggaatg gatgcacaag ggtaaccaga agatcttcga aggactcgac aaactcggcg
     5041 aggcggccga caacctggcc gacgagatcc gcaagagaca cggtcggcag cccgcctacg
     5101 ccggcccacc cggcaatggg cgcaggggaa tcacccgcaa ttccgatgtc gttcatcaca
     5161 ccgcggatcc cacccccggt accggcaagc gctccgagag ccaagccaaa ccacgtcggg
     5221 ccgccgatga tccccgccaa gatgccggcg atcatcagac tcatggttct gacgggaacg
     5281 accccgcagc cctgaactcc gcatcaggtc gcacacctga gcacctgccc ccgggaacga
     5341 accccgccta ctatcctgat ggcctaccgc acccggatcc ccacatgggc aacgagtgga
     5401 ccggcgatac aggacccgga ttcgacaagc ctcgaacccc ggccacggga gattccgatg
     5461 gcggccccgg ggaatgacag acccgcaacc gcgggatgtc caaggcggcc gccgagtacc
     5521 agaagcacgt caccggggtc gatcacaccc tgaacgcgaa cgagaagagt ttcgcgatac
     5581 aggagtacat tgtccgcaaa tccgacggac aatcagtcga cttcgatagc cacgtctggc
     5641 gcagggacgg caacggaaac ccacaggagg tcttcctcga ggccaagaac aaatacggct
     5701 ggctcttcgg aaaatcaaaa ggtctgaagc caaaacgcat ccaaaccatg aacgacttct
     5761 acgagcaaat ggcgcgccaa ctggaagtaa tgccggaagg agcaaaactc gaatggcact
     5821 tccaggaaaa aattgtcgca gacgaggttc gaagaggact acctctagac ttgcaaggcc
     5881 aagtcgacat ctacttcaac ccaagctgaa gcagcaccca gccatggacg acgagcctca
     5941 cgaaacaaga acgagcgtat ttgaacttca catcaccgga cacatgaccc cagaacatcc
     6001 cgaaagaaag gaatgaatga aaaatgacaa accacgacac gcgtgaaacc cctcttgaat
     6061 ggcacggctt caccgccatc tggttcaacc cagacgggaa actacgagac ttcacccccg
     6121 gggtatcccg attcctcaag gatgcagaag aaatagttcc ggactcgaga gggaactggt
     6181 tcatcatcga ggagaacagc accgacgccg aggtcatcgc atccgccatc tcaaccagaa
     6241 aggttccagg cactcgaaaa ctggacggct caccggtcta ttccgaaggc gtctcaggtg
     6301 aggcctacct cgatggcgac cccgacaacc tcgagtcgga caactccgtg ggacggttcc
     6361 ggcttcacag ggctgtcgat cgggctgggc agcagacgtt cgatctcatt cttcacagat
     6421 cgaccttccc catgctgtcc gacctggtcc gctcagctgc caaacacctc caccccgact
     6481 acatctccgg aagcaacatt gctttcaacc aggacatgat caacgcccga accgcctcaa
     6541 agcgcgcggt ttccctcgtc ggactcgtct cctggatacg cggtctccac ccccaagaac
     6601 tcgcaggcta ccccgtgacc aacgtcgaag aatacgaagg cggtctgtac ttcgaggcca
     6661 tctccgacca agccggcacc accctcgccc aactcgccga ccacctcgaa cacatcggca
     6721 cccgccacac actcggcctc ccccccgaac gcagcagctc ggtatggccc aaccgcccnn
     6781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc ccccacgaca tggtttcgac
     6901 acgacccact cgctgccgct cgcaggtcgg ctcaaccagc tccaaggaga acaaagccgg
     6961 gtgatggggt cagaccagtt cggcgacacc ggggccgtcg tgggtctcga tgcggcccag
     7021 cacccaggcg tcgattcccc gcgaccccag cagcgcgacg gccgcgtcga cgccggtctc
     7081 gggcaggatc gcgaccatgc cgacgcccat gttgagggtg gcctcgatgt cggcctgcga
     7141 gatccgtccc gcctgctgca cgagccggaa gatcgcgggc ggggtccagg agtcgcgctc
     7201 cagccgggcc ctccggcccg ccgggatcac gcgcgccagg ttggcggcca gcccgccccc
     7261 cgtgatgtgg ctgaaggcgt gacactcgac ctcgcggatc agcgcgagca cgtcgagggc
     7321 gtagaccctg gtcggggtga gcagctcctc gccgagggtg cggccgagtt cgtcgatgtg
     7381 catctcgagg cgccagccgg cctgttccag cagcacgtgc cgcaccagcg agtagccgtt
     7441 ggagtgcagc ccggaggagg ccatcgccag caccacgtcc ccggcctcga cgcggtcggc
     7501 accgaggatg gcgtcgcgtt ccaccacccc ggtggtcgcg cccgcgacgt cgtactcacc
     7561 cgggccgagc agcccgggat gttcggcggt ctccccgccg accagggagc agcccgccgc
     7621 gacgcaggcg tcggcgatgc ccgagacgat ggcggcgatc cgttcgggaa ccaccctgcc
     7681 gcaggcgatg tagtcggtga cgaacaaggg ttctgcgcca cagaccacga ggtcgtcgac
     7741 gagcatgccg accaggtcga agccgatggt gtcgtggcgg tcgagggcct gggcgatggc
     7801 gaccttcgtg cccaccccgt cggtggaggt cgcgagcacc ggatgggcgt atcccttcag
     7861 cgccgaggcg tcgaagaacc cggcgaagcc cccgagccca cccagcacct cggggcggcg
     7921 ggtgcgggcc acggatgcct tcatgagttc gacggcgcgg tcaccggcct cgatgtcgac
     7981 cccggcggcg gcgtaggcgg actggctcat ttctcctcca ggtgaagcag ctcggcctgg
     8041 cccttcggga ccgctatcgg gtagcggccg tcgaaacagg cgcggcagag gtcggcggcg
     8101 ggacggtggg tggcctcggt gagggcgtcg agggagatgt agcccaggga gtcggccccc
     8161 agcgaccgac agatctcgtc aacccccagc ccgggcgcga tcagctcggc gcgggtggcg
     8221 aagtcgatgc cgtagaagca gggccattcc acgggcggcg aggagatgcg cacgtgcacc
     8281 tgtttcgccc cggcctcgcg gagcatgcgc accagggccc gctgggtgtt gccgcggacg
     8341 atggagtcgt cgaccaccac gagccgtttg cccgcgatga cctccttcaa cgggttcagt
     8401 ttcaaccgga tgccgagctg ccggatggtc tggctgggtt ggatgaacgt gcggcccacg
     8461 taggcgttct tcaccagtcc gaggccgaag ggaatgccgg aggcctccgc gtagccgacg
     8521 gccgaggggg tgccggagtc gggggtggga atcaccaggt cggcctccac ggggtgttcg
     8581 cgggcgagga tgcggccgat ctcgacgcgg gtggcgtgga cgctgcgtcc cgcgatggtg
     8641 gtgtcggggc gggccaggta gacgtactcg aacaggcagc ccttcggcct ggcctcggcg
     8701 aaacgccggc tgcgcagccc cgcctcgtcg atggcgatga actcgccggg ctccacctcg
     8761 cggacgaaac tggcgccgac gatgtcgagg gcggcggtct cggaggccac cacccagccg
     8821 gtggcgagcc tccccaggac cagggggcgc acgccctgcg ggtcgcgggc ggcgaacagg
     8881 gtcgtctcgt tgatgaaggt caggcagaag gccccgcgca gcctgggcag caccgtcatg
     8941 gcgacctgct cgatcggttc ggtcccgaac gaggacatca gcgcggtcac cagcgaggtg
     9001 tcgttggtgg agtccatggt cttcttctcg gggacccgct ggccggggtc gagttcgcgg
     9061 agccaggact ccagttcgtg ggtgttggtg aggttgccgt tgtgggccag cgccaggccg
     9121 ccgttgcggg tggcgcggaa ggtcggctgg gcgttgtgcc acaccgaggc gccggtggtg
     9181 gagtagcggg tgtggccgat gccgagccgc ccacgcaggg acgtgagggt ggcctcgtcg
     9241 aagacctggg agaccagccc catgtccttg aacacggtga tccgctcccc cgtcgagacc
     9301 gcgatgccgg cggattcctg gccgcggtgc tggagtgcga agagcccgta gtaggtcagc
     9361 tgggccacgt cctcggatgg ggcgaagacc ccgaagacgc cgcaggcgtc cttcgggccg
     9421 tggtcgacgg ggtcgagatc gagggatagt cggccatcag gtcggagcac cgactcagct
     9481 tatcgcgggt tcgtcggtaa cccacatccc cgacggaccc cgggaccgac aagccgggcc
     9541 gcacgccact catcccccgg ccccgcgacc cggcaggact ccagagactt cgccggaatc
     9601 ccgcatccac tctgaccaga atgccaagca gcgtctgaat cacacgagtg gcccattccc
     9661 caaaagttgg catccggtcg acctgctggc gagaacctca tagttttgaa tcaggtcggc
     9721 acagggtcaa ccaaggaaaa aggagtaacc atgtccgaca tgaatttcct gaaggaagtc
     9781 gctgatcacg agctctcgca gtccgagaaa acccaggccg gcggcctctg gaccgtcccc
     9841 ggcacccgca ccatcggcgc cgtctgcacc gtttcctggg agtgccatgg tttcatttgc
     9901 ggcttgttca agtgacccag cggaatgact ctaccggcgg tggggtcgtg agggcattct
     9961 cgccccccac cgtcactcac caccacacag gagcccaatc atgcacccaa cagtttacgc
    10021 ggcatttcca gaactgaact ccaccgaggt cgacgcactt ctgcatagaa atcgcgccgc
    10081 cgatgagctg gccaacctca tgtcgcggac cacgggggcg accgcggtca cgtgctgccc
    10141 accggaactg ctccagcagg ctcttgagct gctgcccacc acggactccc cggaacccat
    10201 ccccttcttc gaggcaaccc tggccgttgc ccacgaggat ctgacttgcc tcctcggccg
    10261 gctgagagac catgagctcc tgtcgcaccc ccgcgacacg ctgcgttccg tcctcacggc
    10321 aacggtctcg cagatgcaga atgtcctgct cagggcgcag atccacctcg cctcagaaca
    10381 ccggctcccc gatgaccaga tcacatgccg gacggccgaa tacacacgcc tgtccacctt
    10441 cctggcttcc aagcacggcc tgcggctgtt ccaggaacgt ttcccgattg ccgtacacat
    10501 cgcacgcaac atcgtgcgtc gtcgcaccga tttcattctc caactactcg atcacacagc
    10561 atcagatcta ccatttctcc acgaactcgg agtcgggaac gacgtcaagg tctccaacat
    10621 ctccttgggc gaaggagatt ctcaccacgg aaaatccgtc tccattctga cgttctccga
    10681 caaatccaag gtcgtgtaca agccgagatc cttggcaaac gatcaggctt tctcactttt
    10741 ccagaagcat ctccaggaca tcaccggaaa taccaaattt ctctcatgca aggtcattga
    10801 cagcggtgat cacggctggg ccgaatacgt ggctgataac caagaaacca ggttcgacga
    10861 cccagaggcc ctcggaaatt tcgcggcaac gatccagctc ctcggaatct cggatgtcca
    10921 tttcgagaac gtccgattcc gggacggaat cccaattctc acggacaccg agaccctctt
    10981 ctccagcgtc ctggaatcca gcaggaatcc gctcggccct gccgcacgcg ccctgagcca
    11041 gctggtgacg acctccggat tttttccctc acccttgatg gtgccccaca aacgcaatcc
    11101 catcttcgtg gacgtcgggg tcctggggca gcgtcgtccc accggcagcg gcgaacgatc
    11161 gctgaccctt cgcgacccct tcacatcaga catgcgtatc gagccctccg gcgtctcgga
    11221 gtccctggag gaatcgccgc cggagagatt cgtcgccaag gatttcatcg acgccgtctg
    11281 ccgttccttc cggctgaccc tcacagcggc cctacccgac accccggcgc tgctcgcctt
    11341 cattcgacgc actttcgccg acgtgactgt ccgcagtgtc gccgccgaca cgatccgtta
    11401 ctcaaaggcg ttggagctcg ccaccaacgc cgcgtgcctc agcgaccccg agctcctgtt
    11461 ggccgcgctc tcacgggtcg gcgtctttcg agacgacgtc cccgctcccc ttctcgcctc
    11521 ggaattgagg cagctcgcac agtgggacac ccccgccttc gtcgtagcgg caaccggcac
    11581 ggacctactg tcaggggacg aggtggtcct acccgatgcg atgaccgcat ccccgctcga
    11641 ctcgatcacg aatgcgttgg aacgaatcga cgagaatttc atcgagctca gcgaatggct
    11701 gatccaggtg tccttcgccc cgtactacga agaggacacc gagggcaccg cattccggtt
    11761 cagcaacccg gtcgcccccg gaaccgccac acccacacgt cactcctggg atgcgttgaa
    11821 tctcggattc gtgggcggcg agaacgagtt caccccaacg tggctgggag cgcgcctgag
    11881 cgacaccgcc caccagtact ggtatcccca cgagctcagc atcgacgcat atgcagggtc
    11941 cagcggagtg gccctggcat cggcccatgt ggatggctcc aggacccggg cggacgattt
    12001 cttccgccag ctggtggaca aactccaaca ggccgacctg ctggatcccc gcttcacgcg
    12061 cggcgccctg gcgggaaccg agtccgctct ctgggccgct gactgctacg cacaattggt
    12121 gaatgatgcc gcgttggccg ggcaggcacg ccagttgctt cgcactctgg cggtggctcc
    12181 ctcgaacggg tacgacatcg tggccgggga tgcaggcatg gtgcttttga tgaccaacct
    12241 ggtcgcgaac ccgctcaatg actcggagca gtcgttggca gctcttcgga tagtctcccg
    12301 gaggctcgcg gactgggttc tttcagacag gaaacccatg tccttgaccg ggtacgccca
    12361 cggcaccgca ggggtcgggg ccgcactggc cttggccgcc cctctcgtcc gatccagcga
    12421 ggtcgactcg gtggcacgcg ccgtcctgat ctcgctcctc gacgaacgag atccacggac
    12481 agggttgtgg cccatcggga cggaccacaa gttcaagggt cggggatggt gctccggcag
    12541 cccgggattg ctcttggcac tggcccagat ccactccacg ggacgtttcg atgaccatca
    12601 cctggagccc acaatcagct tgcttgtgga cgccacgaaa cgcgactgct tcggcgggaa
    12661 catctccctg tgtcacggcg acgtgggtaa cctgtggatc ctccgacacg tcgcttccct
    12721 gacccaggac gaccacttgg ccgaggacgt cacatgcgcc tcacggcgct atctcaggga
    12781 ggtcctgccc cgcgagctca ccaaaccaac ccgcaactcc atctcccact ccctcatggg
    12841 cggcaccgga ggggctgcgc tcttcgaggc ctccatggac gaaacccgac ctgccgtgag
    12901 gagtccactg tggctcgcgt gaagacctcc taccaagtca cccagtctga ctgcggcatc
    12961 gcctgcgctc acatggcgct ccggagcgcg ggaagcagac tctccctcaa cgccttgcgc
    13021 gaggcattcg ctcctggacg ggacggactg acgatcccac agctcaagca gctcatcgaa
    13081 tcccagggag ccacggccaa ggtgtaccgc gccatcgtgt ccacagtcca tcgacttccc
    13141 acgccagcca tcctgctctg ggagccgtcg cactacgtgg tcctggaacg gaccgttgga
    13201 aaacgccacg tcatcgtcga tccggctgga ggccggcgcg tcgtgggtgc cgatgagttt
    13261 gctgagcact tcgccggcct ggccctgtgc gtgaccagcc ccgccacccg ccaagaaacc
    13321 cctgatccat ctccgtggcg gagcgtgctc ggtatcgcct ggcgtcgtcc gtacctcttg
    13381 gcggctgtac tcatcggcgc cgttgtcgtg ggtgccacga caatggcact tccaaacctg
    13441 accagtggcc tgctccagca ggcgacgacc acgcctcagg catcgttgac aggaatgctg
    13501 gtggctctcg ccgctggttt cttcctgatc caactgctca acatcgctgt caccaccttc
    13561 tgcgccaccg acatcggcaa gcggctcggc gagacagttt tccacaagct gctcaacgcc
    13621 ccgtactcct acttcgtggt gcggcccgtg ggtgaactgc tcttccgggt cggtatcgtc
    13681 aatcggctgg aggaatcgct gtccaccacc ctcgcccggg gtgtggtctc cagcgtgatc
    13741 gccctcgtca gcctcgggtg gatcgtcgtc gccaccccca ccatcgggat ggtggtcgcc
    13801 ctcatcctgg gcgtctatgt cgtcgccttc gaggccagcc gacgcgtcgc caacaggctg
    13861 accgagaacc tcaactcctc ggaatcactg gccaatgcgg tcatggtgga ctcgctgaac
    13921 tcgatcaagt tggtcaagag cctcgggtct gaacagcagg cgttcacctc atgggtgggg
    13981 cacaacacag ccgcggttcg cacccgccgc acccgagcgt tgctgtccgg tactctcacc
    14041 gctaccgtct ccacgatcca gagcttcggc ccgctctccg tcctggtgtt ggcgatctcc
    14101 cccttgggcg gggcgatggc gctcccagca gcagtgggtc tccagatgat cgccggagtc
    14161 ttcttcagtc agctcagcag tctgggctcc atggccatcg agatcggtga agccaacgcc
    14221 accgttcggc gcatcgacga tatcctctcg gcccaggagg acagcgtttt cgccgacgtc
    14281 tccggcaagg atttccgctt ccccctgctg gccgaggccg cctcgttcaa gttctcacgt
    14341 ttcgcaccgc agaccatcaa ccaggtcagc atccagtgcc atgaaggcga gaggatcgcc
    14401 gtcgtaggcg ccacgggtag cgggaagtcc acgctcgtcg ggttgctggc gggcctttac
    14461 cgccccgatc ggggaagcat ccgctgcggt gaaacagagt tggccgaggt ggccaagccg
    14521 agcttcttcg acaacgtggt ctacgtgccg caggacgccc cattacgcaa caccactctt
    14581 cgggacaatt tggtctgggg ggaccagagc atcgacgatt ctgaactcat cgcagccctg
    14641 aatcaggcct gcttcaacct gagggaacaa ggcctgccga tgggcctcaa cactttcctg
    14701 acgaacggcg gacagaacct gtcggggggc caacggcagc ggatcgccat cgcgcgagcc
    14761 ctgctgcgac acccgcgtct cctcatcctg gatgaagcaa cgtcggcact ggatcaggag
    14821 acggaggctg ttgtccacag gaacctgagt gctgtcgggt gcagcaccat cacggtgacg
    14881 caccggctcg aaaccattac cggagcagat cggatcctgg tcatggatca tggcgaaatc
    14941 gccgagcagg gcaccttcga tgatctgttt gaccgtcacg gcctgttttt ccgcatgtac
    15001 aacgcctatc gaacccatca cgagcttcaa ggagcgacac tgtaatgctc aagatcaagc
    15061 acatctcgaa gtcctatgcc accatccagg ccgtcgcaga cgtctccttg acagtccagc
    15121 ccggcgagat cgtcggcttc gtgggtccca atggagccgg caagtccacc acactgcgga
    15181 tgcttaccgg catggaagaa cctgacagtg gaagctgttc catcaacggc cagcgcatcc
    15241 gcgatctgac cgacccgttg acgacgttcg gggccctcat cgatcggcaa ggcgttctca
    15301 aggaactcac ccccatgacc gctgtgcagt cgttggccgc ggcctacggc atctcgaaga
    15361 acaaggggcg gacactcctg gaacaggtgg gtctggggca cgcgctgcgg cgtcgcgtcg
    15421 gcaccttctc gctgggaatg aagcagcgtc tcggaatcgc cctcgcgctt ctcggggagc
    15481 cgcaattcct catcctggac gaaccgatga acggcctcga tcccgatggg atcatctggt
    15541 tgcgggagct gctgcgcaac ttcgctcggc aagacggcgg agtcctcctg tcctcccact
    15601 ccttggctga agtcgaggaa atggccgaca ccatcatcat ggtgaaccac ggcagcacca
    15661 tctggtccgg ttccttgcag gacatccaca cgacatcctc atgtgtcgtc gtctccacga
    15721 ctgagaatca tcgtctcctc cgcgaacttg ccagacgtgg gctccgggcc gagatggtcg
    15781 acggggtcat ccacgttttc gactgcgaaa acgaggacat agggcggatc cttcatgaag
    15841 gcagcttcgt cccactcacc ctcgcgacca aacgcacctc cttggaagac gcctatctgg
    15901 aattaaccgc ccctgaccat cggaaggcaa gctgatgagc accacaacgt tgagtaatcg
    15961 gatttcggac acgacggcac gtcgagggcg ggaagggcac acacccccat cgcctgtgcg
    16021 cctgcggcga ttcgcctccc tgcgcatgca gagtcacgtt ttcttcggga atcggacgct
    16081 gcttctcaac ttggccgccg ggctcctcgc catgacaggt ttggtcgccg ccgtggcatt
    16141 cagtgtcacc aactcgttca gaagcggcca tccattggac gacccggctt tcgtccagga
    16201 catcgcggtg ttcggattcc ccttcgccca gatcttcctc ggtgtcgtcg cgattctgtt
    16261 catctgctcc gagtggtcct ccggtttcat ctacaccacc cactctgcca ttcaacgacc
    16321 gctgagtttc gtggtggcga agacgatatg gcccgctctg acgtgcgccg tcgggactgt
    16381 cgcaatgatg gtggtcgtgg tgccgctcga gagctggttg ttggcaggca cgccgtactc
    16441 gatctcgttg ctcgacgccg ccgtgtggag gcagatcgca gcactcgcct tcgtcaccat
    16501 gagcgcggtg agcttcgcgg caggcatcgc cctaatcctg cgaaacagcg cgacggccct
    16561 cggactctac atcagaatca tcctgatcgc accgatcatc atcgggcaga tcccggttga
    16621 tacggcgcgc gagatcgcaa aatggctgcc caacaacgtc ttcaacttcc tgaccacgaa
    16681 cgccccgaac gtgacggcca cgctgaacta cccgctcctg atcgcgacag ccatcgccta
    16741 ccccctggcg atcctgacaa tcggcttcct gcctctgcgg cgtcgagtga tctgaggttg
    16801 cagaccggga ttccaccaac gtgagtgtcg cgcaaccggg atgtgcgggc tcagcccgcg
    16861 agattgttca gcagcagggt ctccgccagg gccgccttgg cgaagtcacc gaggtccagc
    16921 gactcgtcga tgccgtgcat ccgcgagttc gggtcggtga cggcggtcac cagcaccagg
    16981 gcttcggagt tgcggtcggc gaactcggcg acgatcggga tcgagccccc gcagccgatc
    17041 tccacggcct cgaccccgaa cgcgtcccgg aaggccttcc gtgcggcctc ggccctctcc
    17101 ccttcgaggg cgatccggct cggcgccccg acctgttccg aatcgatctc gacccgagcg
    17161 ccccacgggg cgtggctgcg caggtgctcc tccagcgcct tcgccgcggc tgccgggtcc
    17221 tgcccgggca cgagacgcac gctcaccttc gcgcgggccg acggcaccag ggtgttggag
    17281 gccttcgcga cgggggtggc gtcgatggcc agcaccgagg cggagggttt gaaccacatc
    17341 cgctccacca ccgacccgtc gccgagctgc gagactccat cgagcagccc ggtctcctcc
    17401 agcaaccggt cctcggggta gtcgaggtcg ggtccgggcc cggagacgag cccctcgatc
    17461 gcgacgttcc cggcgtcgtc gtgcagggtg gccagcagcc ggcacagcgc ggtcaacgcg
    17521 tccggcacga tcccgccgaa ctgtcccgag tgcagcccct ccgccaaggt ggacaccgtc
    17581 acctcgcagg cggcaacccc ccgcagcgac gtggtgagcg agggtttgcc gacctcccag
    17641 ttgacggaat cggcgacgac gtagacgtcg gcggccagtt cgtcgcggta gcggtcgagc
    17701 agcgtcggca tgctcggcga cccgatctcc tcctcgccct cgatgaacac cttcaccccg
    17761 accggcggtt tgccgtcgaa gacccgcagc gccgccacgt gcagcgccac cccgcccttg
    17821 tcgtcggccg atccgcgcgc gtacagcctg ccgtcgcgtt ccgtcggttc gaacgccggg
    17881 gaggtccagg cctcggcatc acccgtgggt tggacgtcgt agtgggcgta cagcagcacc
    17941 gtcggtgtcc cctccggtcc ggggaagttc gcccacaccg cgggtttccc gccgccgtcg
    18001 aggagtttca cctccgaggc cccgaggtcc cggaacaacc cggagaccgt ctcggcgcag
    18061 gcggcgacgt cggcgtcgtg ttccggcatc gaggagatgg acgggatggc gatgagcttg
    18121 tgcaggtcgg cgatggcgga gggcagcacc ctctcgacgt tccaggcgag attggtcatg
    18181 ccctcaccct accgagagcg catcggcagg gaccgacgac gtcagtccct gccgatgccc
    18241 ggccgcggag ttttccggac cctcagccct tgacagcgcc cgcggtcagt ccggcgacga
    18301 tgtacttctg caggtacatg aacagcagga tgatcgggat ggccgcgacc accgcgcccg
    18361 ccgcgaacag cgaccacggg gcgttgcgtt cgtcggaggc ccacacgtac atgccgaccg
    18421 ccagggtgta gtcctccggc ctttgcagca cgaccttggc gaggatgaac tcaccgtagc
    18481 tgctgacgaa ggacagcagg ccgacgacca cgaggatcgg ggtgaccagc cgcatgatga
    18541 ccccccagaa gatctgggcg tgggtggcgc cgtcgatgcg ggcggcctcg tccagttcct
    18601 tcgggatggt gttgaagaac ccgtagatca ggaaagtgtt gccgccgagt gcaccgccga
    18661 ggtagacggc gatcagcccg agggccgagt tgagccccag caccgggtag acgtcgcgga
    18721 gcatcagcag cagcaggaag atggcgacga aggccagcat ctgcgggaac atctggacca
    18781 gcatgagggc cgtgagcccg ccgcggcgtc ccgtgaaccg gtaccggctg aacgcgtatg
    18841 ccgccgacgc ggccatcagc accgtcccga tcgcggtcga gatgctgacc acgaacgact
    18901 gcagcatcca gcgcgggaag ttggtgccga acagtgtggc gtagttctcc gccgagacgg
    18961 tgcggaacag ctggctggat ccactgatcg tgcctcccgg gttgagggag gccgacagca
    19021 cgtagagcag cgggaagatg cagtagagca tcagaaccac cgcgaggatg tgtttccagc
    19081 ccacttcctt ccaccagcgg gcgcccttga gggtgacgtt gtcgttcatc acatgatctc
    19141 ctcgagcttg cgggtctgcc ggaatccgag ccaggcgatg acaccgacca ccacgaagat
    19201 gatgagggac agtgccgagg ccaggccgta ctgtttgcct cccgactcga aggcgatggc
    19261 gtagaccatc gagatcagga tgtcggtctc accgatcagc agcggggagc cggagtagtt
    19321 cgggccaccg ccggtgagca tgtagatcag cgagaagttg ttgaagttga atgcgaaact
    19381 ggcgatcagc agcggcgcga gggaaaccat gagcatcggt agcgtcacgc tgcggaacct
    19441 ccgccacgcc cccgccccgt ccatgatggc ggcctcggtc agctcggccg ggatggcctg
    19501 cagcgcaccc gtgctgacca ggaacatgta ggggaatccg agccacaggt tgacccccag
    19561 gatggcgaac ttcgccaggt tcccgtcgga cagccacgcg atgtcggccc cgcccagcat
    19621 ctggttgatg atcccgaact cccggttgag catgcccttc caggtgagag ccgccaggaa
    19681 cgcggggaag gcgtagggaa gcaggaagat cgcgcggtag aaggtgcgtc ccctcacccg
    19741 tttgtcgttg tagatcacgg ccagggccag cccgagggcg aacgtggtgg ccacggacag
    19801 gatcgcgaag gcgaacgtcc aggccgtgat gctgaggaac ggtcccgtca gccgcgagtc
    19861 gttgaagacc tcggtgaagt tcctggtccc gacgaacacc cgccagcccg gggtgagctg
    19921 cgatccgtcg ctggcgacgt aggctcccac ggactcgtcg gcgtggtaga tcttcccgtc
    19981 ggggtcggtg aaggtgtcgg ccgcggcgtc gtgggtcaac gccgacttcg cgacgtaggc
    20041 gaaggacgcg ttgtcggtgc gcaaccaccc ctgggtgggg tcgtcactga ggttgacgcg
    20101 caactccagc acatccttct gccgtgcctg cacgtcaggc ggcgacagca cgttccaccc
    20161 gggcacctcc gtcaccctgg tgccggcgac aaccgctccc tgcacctcag cgagaggagt
    20221 gttctgggtt ccggcctcgg cgtggccgtc gcgcaccacc gcgaatccca gttcgccgtc
    20281 cttctcgacg acggtcacgg gataggttga ggtgccctcg accctgcggt cagaggcctt
    20341 gaggatctgg gtgatggcag cttgcttgga gtcgttgtgg ccgtcgccgt agttggtgaa
    20401 cgccacccag gccgtcgagc ccatcacgta gacctgatag acgagcagga agaccaggcc
    20461 gggcagcagg tacttggcgg ggactgctcg cttggagaag tagacgtagt cggcgacgag
    20521 cagcgtcacg gcgaggaaac ccagcacgag ccattgccgc tggggaatcg agaccatgat
    20581 gccgtacagc ccgaaggcgt tgaccagggc catcaggacc agcttcgcgt agaagccggg
    20641 acgcgtgtag tcgcgggcgt gggacagccg cggctctgct gggtcggttc tttctttcat
    20701 gttgttcccg gaccggaaac cacgcggggg ccggagcgcc cccgcgtgga gcaccgatca
    20761 gcccttggcg agcgcgtcct cgacgttgga gatcatctgc tgccaggtgg acaccggatc
    20821 ctccccgcgg aggatgctga gctcggcgga accccagtgg ctccagacgg catccatggt
    20881 ggtgatggtg gcgggcaggg gctggccgct ctcacctgcg gtctcgaagc ccttgaggac
    20941 cgggtcggtg acggccgccg cggcggactt cagcgcgggc aggcgcccac ccttttcctg
    21001 caggatcttc tgcgcctcgt caccggccat gtagtcgagg aactggttgg ccagcagcgc
    21061 gttcttggag tacgacgaca ggtagacgcc ctgcaccccg atgaacgggg cggacggctg
    21121 gccgcccgcg gagggcacgg gcagcaccga gatgtcgagc ccggccttgg tgaactcgcc
    21181 ggtccaccag gggccggtga tgatgtaggg ggacttgccg tcgaggaagg cctgcttggc
    21241 ctggtcccct ccgatggact cggacagcac accctcgtcg gtgagcgtct tgatgtaggc
    21301 ggcgaatttc tcgccggcct cacccttcat gccgatctcg gtggtgtcgg gcttgaacag
    21361 cggggcaccg aaggagctct gcaccgggta caggtggtag gcgtcgccct tgtcgccctg
    21421 ctggatcagc acgggatggt ccggggtgag ctgtttgccc tgggcgatga gttcgtcgaa
    21481 agtggccggg gtgtccttgg cgagggcatt gttgcgcacc agggcgatgt tctccaccgc
    21541 gtagggaacg ccgtagaggg tcccgtcgct ggtgaaggcc ttcttcgcgg catcggagaa
    21601 accgtttgcc ttgtcgccga gttccacggg tgcgacgact ccgttcttga ccagactgcc
    21661 gacccagtca ttggcgccga cgatcagatc ggggccggcc ccggaggggg cctgggcgat
    21721 gaagtccgtg cgaacgtcat cggtgggttt ctgcaccacc tccagtttga ccccggtggc
    21781 cttctggaag gcctctccga tggcgttgaa accctcgatg cgggtctcgt cggtccacac
    21841 agtgagggtt ccggatgcct gggaaccgcc ggaggaactg ttcgatgtgg tgttgcttgc
    21901 ggagccgcag gcggtcaggg cgaggaccag gccggtggct gccagggcga gcaggcgctt
    21961 gctcatgtgg ttctcctgtt ctgcgggtcg acttcgacgc cgctgatgca aaacgctaac
    22021 aaaaactctg catgtttgca gcaatttttc agaaaatctc ggccacaatt tgataacgtt
    22081 cggcagacag actgaccaac ggaggtacgg atgagcccgc gaccacggat gtcggacctg
    22141 gccgccagcg ccggtgtatc cgtctccact gtctcccggg tgctcaacgg caaacccggg
    22201 atccgggaga acacgcgccg ggcggtgctc caggccatgg ccgacttcgg ctacgatcgt
    22261 gaaaaattgc agcaacgcac cggggtggtg ggggtgatgg tcccggagct gtcgaacccc
    22321 tccttccccg ccttcgcgga gcgcctggac gccatgttcc agcccgtcca ccgcgccgtg
    22381 atcgccgcag ccggtccgct gggcgcgaac gagtcctcgt gcatcgccac cctcctggac
    22441 ctgggggtcg acggcgtggt gtccatatcg ggtgccgccg ccgacaccga ggctgacctc
    22501 accccctacc tgcggctggt ggaggccggg gttccgacgg tcttcatcaa cggccacacc
    22561 acgaaactcg cctcggcctt cgtgaactgt tccgatgccg aagccgtcgc cgcctctgtc
    22621 gcccatctga ggtcgctggg gcacgaacgc atcgggctcg ccgtcggccc ggcccgtttc
    22681 ctgcccaccc agcgcaagtc gtcggccttc ttggagctgg gtttcgggaa ggacagcatc
    22741 gaacgcacca tcttcacccc ggagggcggc caggtcgcgg cggcgagact gctggcgacc
    22801 gggcacaccg ccatcatctg cggctccgac ctgatggcgc tcggagtgat ccgtgaggcc
    22861 cgctcccggg gattccgggt cccggaggac ctctccgtga taggtttcga tgactccccg
    22921 tt
//
