LOCUS       NZ_LR027842            28149 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  [Pseudopropionibacterium] massiliense strain Marseille-P6184, whole
            genome shotgun sequence.
ACCESSION   NZ_LR027842
VERSION     NZ_LR027842.1
KEYWORDS    WGS; RefSeq.
SOURCE      [Pseudopropionibacterium] massiliense
  ORGANISM  [Pseudopropionibacterium] massiliense
            Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
            Propionibacteriaceae; Arachnia.
REFERENCE   1
  CONSRTM   IHU Genomes
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2018) URMITE, IHU - Mediterranee Infection, 19-21
            Boulevard Jean Moulin, 13005 Marseille, France
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900607225.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:04:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,146
            CDSs (total)                      :: 3,092
            Genes (coding)                    :: 3,052
            CDSs (with protein)               :: 3,052
            Genes (RNA)                       :: 54
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 11 of 40
            Pseudo Genes (incomplete)         :: 35 of 40
            Pseudo Genes (internal stop)      :: 4 of 40
            Pseudo Genes (multiple problems)  :: 7 of 40
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:23:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2419557
            Orig. end                         :: 2447706
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LR027842.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..28149
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="7"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..28149
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28149
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:18149](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..18149)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    1503..1519
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.78"
                     /tool="antismash"
     gene            complement(1855..2025)
                     /locus_tag="E0E39_RS15815"
     CDS             complement(1855..2025)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E0E39_RS15815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_165444745.1"
                     /transl_table=11
                     /translation="MDGKITKRQMALGVSMVYGGLVAAMAALNYTDVMLIVVLVGGPAV
                     AWAWYVASRDK"
     misc_feature    complement(2615..2630)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.47"
                     /tool="antismash"
     gene            complement(2693..5536)
                     /locus_tag="E0E39_RS10810"
     CDS             complement(2693..5536)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="E0E39_RS10810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_130874737.1"
                     /transl_table=11
                     /translation="MKPEVPHGLVRALTARDRLDLTSGHESFLVVKGRVRVFAQKAQGR
                     LEPLFTCGPGDALIGAGVVGSEWRLVAIGLPETGLAPLDLERLAREAREQGPNRMLIMM
                     LENWVSRLMAATCPSVVMAADAFVPTEDADFKSAEGQAHVLRHRFLWLTLPHPTVIWGH
                     VFDHVVAWPAHLMLRFDSKMKGKVIGSSEALCRRDTWDRLNSLQPDCFAWLETRLAISR
                     EAMTRREVELRVFQDRVGDTVQSQCWFSGEGSQDLASSNVLTSSFVSALTVVCRAVGAN
                     FTPPPVGALNATRDPLALCARASGFGYRRVNLDAKWYEGDVGPLLGHMSGDQERWVAMI
                     RHRGVFRVHEGTGGLGAPLNERIDRAIDQTFQIYPALPRGGVLRFLLFRQWPALLMCAV
                     LGAVLGLMAMLPIFVLEFFRGEGHDPALISKPVGLVWALLLWVGGVAFLELFAHRLVSR
                     IVSFVGTRFSAAVFHRLLIGQSEEVVRRSPAERSGMSAELLASEDRILQLVYGVGAGLG
                     LILSGFSSMAWVSPRSMLGCALTCVLISVMFGTSARRCRRAEKVLRAMRAEQNSLSASL
                     LGSVSSLRVAGASQRASLMWSVHDAGQQYWRRIVLRGQLFRRRLILLGIALLVVAFLMT
                     GDAQEWMHNPLGVPAAGVSLSLLSAGLIILGGALGQLSGLLDVAGEVKKLAEAEEAPTG
                     VGVIPDGPSGFIEVDGLTYSAAGDGSTLIDQVSFTVKRGSFVAIVGPSGSGKSTLIRLL
                     LGLIRADSGSIRFDGLDISTLDLVALRERSGVVLQALSLPKGSIQSIISGGRNLGKEQV
                     LAALRVVGLGALVDSLPMGVNTLISGNSGVFSGGQMQLLLLARAIAGAPRLVVLDEATS
                     ALDNNSQAAVMRAIEQLNATRVVVAHRLSTIRNADHIIVLEKGTVVQEGTFEQLERQDG
                     LFRRLVQNQLKGSARTS"
     misc_feature    complement(2939..2941)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4223..4225)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5526..7718)
                     /locus_tag="E0E39_RS10815"
     CDS             complement(5526..7718)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="E0E39_RS10815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="WP_130874738.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.6e-32, bitscore:
                     108.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMSRDPRVAPFVTGSLRVPVLLQQEVVECGAACLSMVLAYYGKWV
                     SLAQSRAVCNVGRDGVSAAAILKAARSFGLEARGMRSEPENLGDLRFPLIVYMEFRHFM
                     VLVRGTKRGVVVNDPGFGQRTMSWEEFDLAFTGIALELTPGEGFTQTGQRPSVLKELAR
                     IIAPERRNLALALVAGGVGALALMAIPQLLRVFVNGLYGSLTSRRLPTDVLSALAILSA
                     VVVALVLWARDRALVLSAVYRSCDEARSLFGRIMLLPMSFFRLRHRGVLASQIQSFESL
                     IVSVVVNLGTLFGELLILFGALATSVLVNPQIGAVIVALVLLWGVVVAGVGRWAEPVMN
                     RRVIAVSNQAGGAAAAFYDLERIRANGDEGNIYGRWTGAMAAMSSDTSRAQMVSLLYFA
                     MPIAFVGAGSLMVTWVAALGILAGQIPVGEMFQMQLLLLLAVLAAQGCVTSIAGFAGMS
                     PSLALARDVGPHARLEDVDQDVTMISGDRTAEPLSGAVKVSGLGLLVDHQTWLLKDVTF
                     SVAPGEHVAVVGRSGAGKSTLAHLLAGLEEPTQGAVTFDGLARHELARATLTRSVAYVE
                     QLGSMLRGTVRDNLALWDPTIPDAVLLAAAKDAGILADILAKPGGLDRQVDVERPEWSG
                     GQRQRLAIARALVKDPSLLILDEATSGLDPIVEREIYDTIRARGCSVVIIAHRLSTVRH
                     ADLIVVLDGGVVVEQGTHDELIDRHGCYWELVNDEA"
     misc_feature    complement(6210..6212)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(7245..7247)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(7617..7619)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7705..8298)
                     /locus_tag="E0E39_RS10820"
     CDS             complement(7705..8298)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E0E39_RS10820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_130874739.1"
                     /transl_table=11
                     /translation="MAGFRLKALTKARVADPTTKKMSISPLRGWLAFVGACLIVAGSLL
                     WAVYSTLVVSITSDRSFFSPDDSGRQQAYALVSIVEAQQLRTGMEATVSLSGFPASRFG
                     RLRGRVESIDSVPVGRERLVQLLGAEELVPDVTRGAPGYLVEIRLLDGTGPEGFEWTHG
                     GAPEGLRLLRGAPAQVQIVLDLFHPYEVLFDDES"
     gene            complement(8305..9045)
                     /locus_tag="E0E39_RS10825"
     CDS             complement(8305..9045)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="E0E39_RS10825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_130874740.1"
                     /transl_table=11
                     /translation="MKFQYIGYELLRLWRNKPFFFFSLIFPIALFAVFALTMGESKIPI
                     GTHDIPVIIYYMASMAGYGALMAALSGGARISTERSSEWDRQLHLTPLSSSQYMFAKVV
                     TAYLMSALSMLLIYLTGVLLGARVEGIGRWVVMSGLILVGVLPFAILGIALGLILSTDA
                     MGPALGGAGAFFGFLGGMWFPFTSGTIMDHIGQLFPSYWIAQASLSAMLDVQWPLMAWV
                     VIIGWVVGVTALAAWGYGRSGERG"
     gene            complement(9042..9986)
                     /locus_tag="E0E39_RS10830"
     CDS             complement(9042..9986)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="E0E39_RS10830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_130874741.1"
                     /transl_table=11
                     /translation="MVNAVELIGLEKSFKTAGGVVHAVQGLSLTILAGQRVALLGPNGA
                     GKSTTIDMLLGLTRPDRGEVRIDGEDPRAAVRNGRIGAMLQNGGLIGDLTVRELLSMVA
                     CLFPNSMSVEAAMEIAHVSQHARKRATHLSGGEAQRVRFAIALVSSPSLIVLDEPTAAM
                     DVQGREDFWATMTTLEDRGMTALFASHYLAEADMYADRVVVIVAGKIVADGPPSAIKAM
                     AGGRIIHAVVDSREVARFAGMDGVQSASFVDGRLQLDCSDSDLALRELLRVAPDARGIE
                     VAQRGLEEAFLAITSGNSAQVRGALNNNDGSTS"
     misc_feature    complement(9957..9959)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9963..9980)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            complement(10001..11962)
                     /locus_tag="E0E39_RS10835"
     CDS             complement(10001..11962)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="E0E39_RS10835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_130874742.1"
                     /sec_met_domain="PF04055 (E-value: 6.3e-12, bitscore: 43.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDFGTSKTCRLFELTPTQGYTYSAALGYLSAVCQADPIVGTSWS
                     VTQEVHQLAPFDPASGVDEVIASLGRGRVPDVVGFSVSFWNRRPSLECARVIKQKWPDV
                     KVVLGGSDVSFQGDVLLADGSPLDFIVNGEAESTMPELLHAIEHDRPWGEVHGISYRAH
                     GEVQTTPRRALIADLDSIASPFLTGVVDPKSLSEATLLVYESNRGCPYSCAYCFWGGAT
                     RTAIRCFSLERIERELDFIVAHCRPHMVFFLADANFGILERDLDLARLMVEACERYKKT
                     ITFNTNWTKKPREATLEAARILYSAGLLGGVTVSVQSFDRSVMRKAKRINIKPPAYRDL
                     LARLRSCNIATYTDLIWGLPGQTYETLLDDIDTCLNAGGCPVAYPLLLLPNTEFFSPEM
                     REAYAMETEPIPSDLTTPALTGEMVVAHSTLDRENWKRGMRLIMGMNLFWKCLFRATIT
                     YVAKVMKLKYSRILDLLTEEMYGGSLGDPVVGALLEDFERTIAGFQPPHSQRALSMIGE
                     SGLPEQAHFQALLKRFVHGDPGERALGHLALTLQSLAPDVELAGAMGIDRVARLTIRSS
                     LREVVPCVVELSPTVETVLIGASVLPVAEGIGEERRSLRSGDVSDRFRFPAYALAIWHG
                     GANPLKDAEPVIESAEML"
     misc_feature    complement(11072..11074)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11360..11362)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11603..11605)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11962..13209)
                     /locus_tag="E0E39_RS10840"
     CDS             complement(11962..13209)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012517.4"
                     /locus_tag="E0E39_RS10840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_130874743.1"
                     /transl_table=11
                     /translation="MTKVIIQTYPTVGNLKEMAKYRPIGRNTEMFQRLLEEMRALAVAA
                     DALGYWGISHTEHHFHSEGVELSPDPGLYNLWAGTATKRLHHGQLGYVLPTHDPVRLAE
                     RTAMIDQMLQGRFFVGLARGYQSRWCDVLGQRIGVGGSDHGDKERDNLNWSLFREHYRI
                     LKMAWTWDLAKYPGTYYRIPASREETPPWQPAQGMTDTYGVPGEVDSNGQVKGVSVVPR
                     PYQKPHPPLFQAHSISPRTIGWCAREGVTPIIQFPSLAACRALGEYYRRQAGEVGRKLQ
                     LGDGMGLIRVFHIAEDRGAALAASQKYDDLIWNHWYRYFRYLELFRLPDEEGEVPKPGE
                     LVSERLAGAGMSILGSVDDVKRGVEKTLNEFPVEYLVWHLAWRPMPAEEAIRQLELFST
                     HIMPEFDLEFAGEQDH"
     gene            complement(13211..14146)
                     /locus_tag="E0E39_RS10845"
     CDS             complement(13211..14146)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013696.4"
                     /locus_tag="E0E39_RS10845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="WP_130874744.1"
                     /transl_table=11
                     /translation="MAEYDALPGIGHACGHNLVSGASLAAFMLLMRVADQIDLKVTLFG
                     TPSEEFGAAKVELAESGAFDGVNFAMMAHPAPSGVDAPRMAALARYQVGIESAASGHSS
                     AYSSGVTVSEAWHVLATGLGLLPRQLPRGAIIDWEVLSTSGSAAVHARRLKADVILRAW
                     EDAHLQAAAEALATTCGAVATITRTKIECSLAQRFMPAMRQNVGLARLWRGNRAALGMT
                     SQAVPFPAATDLGALSLRIPCLHPYFNIGCWPAKNHDPEFTQAAVSERAHSAMVNAGTA
                     MAMTVVDVAAVGYSTLHEKNYTESISKQRS"
     gene            complement(14415..15749)
                     /locus_tag="E0E39_RS10850"
     CDS             complement(14415..15749)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.4"
                     /locus_tag="E0E39_RS10850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_165444746.1"
                     /sec_met_domain="PF00881 (E-value: 6.6e-16, bitscore: 56.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDAHREAMKSFWKSLLDGPVDAQLALTEVAGHGLPVLAYARSLL
                     RALSVAGWLRQECAGVDEKGEFERVINLEPIAPAPGRLGFGAQESVGLETMLYLKRSVM
                     FAVEKGGIIMEAGDVRYIAAIQSKWALELLYLTAKGSSISELREAIPGLESAVVAEILG
                     MLFEVGFLSTEPQEGPALWAPWEMLFHARTRVGRSVGGYGGTYHFKGITDPASGLPPGR
                     GGERISLTVPDMERSLSLVAASESRRSIRQQDPHRPLTLDQLAALLYRVQRTRAVRSDG
                     ENGDVLSRPYPSGGSLYELEIYPLVTNCAGLEPGVYHYRSESHELERVSDFDERVSKLA
                     GLMGHTTLLENLPQVVLLITARFPRVMWKYEGVSYAVILKNVGVLYHALTLHATDLGLA
                     SCPVGGGDSDVVADILGSDYFEETTVGEVILGSIPDSHDVVSFRE"
     misc_feature    complement(15207..15209)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15357..15359)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15906..18149)
                     /locus_tag="E0E39_RS10855"
     CDS             complement(15906..18149)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03604.1"
                     /locus_tag="E0E39_RS10855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_245988479.1"
                     /sec_met_domain="YcaO (E-value: 1e-77, bitscore: 259.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 3.5e-69, bitscore:
                     230.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRMRPRLRANVDLVELGNGRMLAVSGTRFLALEMAHMRVLASLLD
                     GEHRMTEIWRGTKGVMSPALVVRIVMMLEAVGFIADGPAVSVGAEGAFLDSIGVDSPIG
                     GVAVMMLGLAEQTRKLCEAALDQICREWRRVELKSLGLAEGGESPLLVITPDYLAEELA
                     EINRVMLKLDREWALVKPFTDEIWIGPVFGREEGAACWACLSQRLKGHRILEKYAELET
                     GRRVPVGNLQSGVATSITLALSAALLRLVAGGPSDLLSIELPEFAVQSHVVTKRPQCPV
                     CGDTRVDPIGFELVSRPKGRDDSGRPLKRVKSLSETRESLERHISPYSGVITKLTPIDS
                     DSDLYFSAAAGHDFAPSRTDFSLLVKTLRGSLSGGKGRTPRQAEVSALCEAVERGLTMY
                     TGDEPVVTATYREVADSAIEPSLLLGFSDHQYLNRIALNEGNPSKYAFIPNRIDPDAVI
                     DWCWVKDVGSGPNRLVPASYCYYGHPDLYSRCYCLADSNGSAAGGVLEEAIVSGFSELI
                     ERDSVGIWWYNRVRCPGLDLDSIDDSYLMALRQEHKRMGREVWALDLTTDSSIPCFALL
                     SARLDGSPEDIIVSFGCDLDPKLALDAALDELNQFLPWVSRDENGVTRYRGVEPEAVDW
                     FQNATVSSDPYLLPSETLPFTRLDQIHGLRTDDCLKDIQVCKDIAERLGSRMYVMDLSR
                     PEVDVAVARVIVPGLCHFWRRLGPRRLYEVPVAMGYLAKSHSEDELNPRTVYF"
     misc_feature    complement(16191..16193)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16839..16841)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18444..18812)
                     /locus_tag="E0E39_RS10860"
     CDS             complement(18444..18812)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E0E39_RS10860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_130874747.1"
                     /transl_table=11
                     /translation="MSMEFKEFEDAYYALLTRAWTSEDYTMEMMANPVPALREVGFKVP
                     DGVELTVLRAIAGDGDLSDQYRMWNEGIEAGAVTVVVPEVPPVDLGDLGELTEAELAEM
                     PGGTSYCCSCTPCCTCTA"
     gene            complement(19263..19490)
                     /locus_tag="E0E39_RS10865"
     CDS             complement(19263..19490)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="E0E39_RS10865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_130874748.1"
                     /transl_table=11
                     /translation="MRCWFHKIANLLDALLKSAHPGAKAALAENWNTEDNTSRSNSVRR
                     RVWGDVPEMAAKITDDLDVLSAFHNYPGER"
     gene            complement(19880..20305)
                     /locus_tag="E0E39_RS10870"
     CDS             complement(19880..20305)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033564.0"
                     /locus_tag="E0E39_RS10870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ISAs1 family transposase"
                     /protein_id="WP_130874749.1"
                     /transl_table=11
                     /translation="MPAHHSTTTGHGRRVRRTIKVCQVPDRIDWPGARQVAQLRRTRTI
                     DGRKTVWGVVYLITSLDAHQTSPADLIQSHWGIKNRLHWVRDVTFDEDRHQLHTGHGPT
                     LMTTLRNTAISLHRLTGTVNITTALKHHSRDPLRPLH"
     misc_feature    20570..20580
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: strong, score: 22.05"
                     /tool="antismash"
     gene            complement(20577..20972)
                     /locus_tag="E0E39_RS10875"
     CDS             complement(20577..20972)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025180.4"
                     /locus_tag="E0E39_RS10875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase family protein"
                     /protein_id="WP_165444748.1"
                     /transl_table=11
                     /translation="MCSSSLTIPVCGQWLLGVFVTIADLRGRRGRCYDLAGVLAIATAV
                     VCAGAGGLVAVAEWAADVGRDLLAKSGLLRLGCRVASESTIRRILQVLDPDELSAMVGA
                     WLARDATRWKGRMVVVDGKSLRGAKIS"
     gene            complement(<21099..21547)
                     /locus_tag="E0E39_RS16415"
                     /pseudo=""
     CDS             complement(<21099..21547)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014358297.1"
                     /locus_tag="E0E39_RS16415"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS256 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLKVVPEENESKKHAPAAGCCSMSWHAKAHGRC"
     gene            complement(22052..22957)
                     /locus_tag="E0E39_RS10885"
     CDS             complement(22052..22957)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014845851.1"
                     /locus_tag="E0E39_RS10885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_130874752.1"
                     /transl_table=11
                     /translation="MTSKTKLAALGIAAALALAGCGSASNIEGRSDDTNSSDTLVIGSQ
                     DYYSNEIIAEIYAQSLEKSGKKVDRQLKIGQREVYMPELQAGKIDIFPEYSGNLLQYYK
                     PETTARTPEQVHAELVGALPEGLKALEQASATDQDSYVVTKAFAEQYSLKQIGDLASVP
                     DLKIAGNSELESRPYGPKGLRETYGVEATIKPAEDAGGPLTVKALRDGDVQIADIYTAA
                     PVLADGDLVALEDPKNLFLSSNVVPIVSKKVDDQTAETLNKVSKELTPEDLIAMNKRSV
                     DEKASASVIAGDWLKSKGLA"
     gene            complement(22954..23646)
                     /locus_tag="E0E39_RS10890"
     CDS             complement(22954..23646)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014845850.1"
                     /locus_tag="E0E39_RS10890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_130874753.1"
                     /transl_table=11
                     /translation="MNLFLDALGWLFTPENWDGDSGISSRLLQHLAFTLTVVAVACVVA
                     LPAGVAIGHTRRGVAVVPMVTASARALPTLGLLTLVGLWSGLGLVAPFCALLVLAIPPM
                     LAGAYSGITSADPVTVDAARAIGLSSWQVLTQVELPAAVPLLLEGLRSTTLQVVATATL
                     AAYTADVGLGRFLFTGLKTRDYAQMIGGALLVVALALVLDLLLVLAKRLVTRELDPSTQ
                     IASAKESR"
     gene            complement(23643..24293)
                     /locus_tag="E0E39_RS10895"
     CDS             complement(23643..24293)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014845849.1"
                     /locus_tag="E0E39_RS10895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_130874754.1"
                     /transl_table=11
                     /translation="MTWLINNLGQVGSYFLIHTLLSLSAIVAAAVLSVPLARLAVATRR
                     FGGLLLGAFSLLYAVPSLPMLVVIPVILGVPVRSPLNMVIVLTLYGISVLVTQVAEAFR
                     SLPEEVVEAANALGVDPWRRFWQMELPLAVPVLIAGLRVVAASTVSLVTVGALVGVQSL
                     GTLFTDGFQRQLVESLLTGLGATLLLALIFDLLVVLLGRALTPWVRKQKQVTA"
     gene            complement(24290..25138)
                     /locus_tag="E0E39_RS10900"
     CDS             complement(24290..25138)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014845848.1"
                     /locus_tag="E0E39_RS10900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_130874755.1"
                     /transl_table=11
                     /translation="MIRFEDVRKIYPDGTVGVGGVTLDIAEHSTTVLLGSSGSGKTTLM
                     RMVNKMVTPTSGVVLLAGEDVAVQPTVALRRSIGYVLQDGGLFPHRRVVDNIATVPILD
                     GVPKARARERSLELMDMVGLDRDLAERFPSQLSGGQRQRVGVARALANDPKVLLMDEPF
                     GALDPLVRADLQRELRDLQRRLGTTILFVTHDVDEAFLLGDQVAVLRTGGVLAQVGTPE
                     ELLSNPADEFVADFVGADAGRRQLRTIERNGSRLVIDAEGRPLGSLRADDGGGNRDRES
                     S"
     gene            complement(25135..25692)
                     /locus_tag="E0E39_RS10905"
     CDS             complement(25135..25692)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013231.4"
                     /locus_tag="E0E39_RS10905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_130874756.1"
                     /transl_table=11
                     /translation="MKETAAPLGDHGALFEALLHAEVALWNRLEKDLWRTANSATLARY
                     LVLKQIDASAAEGGPRVQDIARRQHTTVGAASRLVDRLVGDGLVVRTPCPRDRRSCRLS
                     LTDKGRMRMESAAGTFENTLRTVLAGFRHEELVVLTRDLIRVAAGAGQRADVVPAMQGA
                     RLDEPLPGGGFVALTNENGAES"
     misc_feature    complement(25707..25723)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.94"
                     /tool="antismash"
     gene            complement(25822..26835)
                     /locus_tag="E0E39_RS10910"
     CDS             complement(25822..26835)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014845845.1"
                     /locus_tag="E0E39_RS10910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydroorotate dehydrogenase-like protein"
                     /protein_id="WP_130874757.1"
                     /transl_table=11
                     /translation="MAELRSSYLGLELRNPVVASAGPLSQNVEDIKALADAGVGAVTMF
                     SLFEEQLFRDAERLVELEEQFADITPEATSFFPEVPRAETDAVTSYLRLVEKGARAIDV
                     PLIASLNGASRGGWVHSARSLQDAGAAALELNIYYVSGDFALGGDEVEQRHLDILRAVK
                     SEVDIPVAVKLSPYFSSVGAMCQRLDRAGADGLVLFNRFLQPDIDLERLEVVSGVTLSS
                     PVDARLPRTWIAVLHDHVEASLAASSGVDQPEDVVKYLLAGADVVCTTSALVRHGIGHA
                     TRLVEGLDAWLDGRRLTLDQARGMLAVPSHTPADVYERAGYVAALEKAKTTYGSLS"
ORIGIN
        1 acgaggatcc atcccagcgc ggtcgtcccg atggcgggaa cccatgcggc catgaggaac
       61 cggtagagtc tgcgcgcctg ttccaggacc gccccgtccg gttcctcccc catcccggcc
      121 gaggtgtggg cgacgtgcgc gcgttcggag gccagggcca gtgggtagaa ggacgcgtgg
      181 gcgaggggtg acaggcagaa tccgatcccc aggagcgcca cccccgccac cccgatcgcc
      241 gagtcgcgca gcagcaccca gtgggcgtag agaccggcga gcatgagcgg tgcggaatag
      301 ttccccacca gcgcacccca cctcaggcgg ggttcgtcga tgcgcgtgta gaaggcgtag
      361 gcgtcgtttc ccatgagatc gatgaactcg ccgtgctcgc gcccgtcggg tttgtggaaa
      421 ccgacgatga gggcgtcccc gacgatccag cacagggcgc tgaccaggaa ggcgagaatg
      481 gaccaggtca ccagcatgtg caccacttcc tcgccaaacg tcaaccacat caagtcgaag
      541 gaatcaccct gcgacggtac tccgcacgtc agagacggct agggaacctg aatagtatgc
      601 gcgcacagcg gcagggcggt gtcatagggt cgtagcaaca gtgcttgtca gggagggggt
      661 tgttggtgcg gcgtatgttg atgatgcagg accgggcggc gatcgcgaaa gggttgaagg
      721 agggatgttc gctgcggcgg atcgcggacc ggattggcag atcggtttca gtggtgtctc
      781 agggggatac accgtaacgg cgggaagtgc gggtatcagc ccgtgtggca gccgatgcga
      841 acgctcagaa acgccggacc ctgggcgaag acccgcaaga ttcgatgccg catcgggtcc
      901 tcaaggttcc gggtgcagga caggttctgg gagtgttccc gggacacccc tgccacattc
      961 gctgcgggga ctccgggcgg aggccggcga tggcagtcta gagaatctgt gcaagggctc
     1021 cccaagtagc tgaagggagt agttggtgtc ctatgaggcc atccacacac cagggttcta
     1081 taccccttcc cggcaagaag gatctggccc gtcataggag tcatgcctgt gctcgaagcg
     1141 caccagaggc cggccgcgcc gcctggcggg tgctgcgtac ccgatccgat cgtgggaacg
     1201 gtgcagcatt gcggtgaccg ccccgaggat gtggatgatc gtagaaccct ccgggaacac
     1261 atgggaggtg tgtcctgaac aatcgggaac cgatggcgcc tcagcagcgg cggatcctgg
     1321 aggggacgca ccacccggat ccgtggatga tcctcgcccc tgccgttggg aaaggaacat
     1381 ctgaggggtt gtgtgatgtc tttgatcgat cacaaccgac accacaccct gatgtgatgc
     1441 ggggtctccg tgccctcggt ttcacggttt cgaaagatgc acctgtcatg ccgcactcac
     1501 cctggcaacc gacatgcaag atgtgtcttc gtctcgtcct cgctcccccg tagggagcgg
     1561 ggaacccatc gagaacacag gcgggctgaa tctgtgagta cctacccaaa ggcacccgga
     1621 tcaccacaca tcagccctac cacaggcgcc atcgctgaag agcttgggtg gacgccccag
     1681 agcagccctg gggtggccca actccacgcg aagcatacga acgcctactc gttgcctcca
     1741 ccacttgaca ccaagcaggc gcgtccgttg gagttggaag cggagtttag gacacagctg
     1801 aaaagcactg atttcccagc cccccgtcac ggcactgatc aagcagaaga accgctactt
     1861 gtcccgggac gccacatacc atgcccaagc gacagctggg ccgccgacga gcacaacgat
     1921 cagcatgaca tcagtgtaat ttagggccgc catggcagcg acgaggccgc cataaaccat
     1981 cgatacccca agggccatct gtcgtttggt gatcttaccg tccatgtcat ccttctttga
     2041 gcctaagttg cggtatacca tcattctaca tccaactttc acgcaatgag ggcttcttga
     2101 ctaggcagtg caggtacagc acgaccagca acaggtggcc ccacccggcg tggcctccag
     2161 ctcagtctcc gcaatttccc cgaaatgaac cggttcgggg tcaggcagat acagccgagt
     2221 cgattcaacg gcaatgccat tgattcacat ctgatactac cgttaaagat ccgcttcccc
     2281 atccgactga cgaaccacgt ccacgtcaat gccaggagga acatcgaatc ccacctcacg
     2341 aagagccgaa ggcgggtccg cgaggatttc cacaacgtac tcttcgctga tccacgccct
     2401 cgcgagcagc gcaaattatg cctctccaaa ctcagcaaac tccaatttgc cccctcccct
     2461 tctgacccgc ccgaagcggc cgcatcgacc ttcgcgttga aaaggacctg aacctgacgc
     2521 ccgcggactc ctatcggaac gacacccggg ggacacccca aatcatgaat cgaatccatc
     2581 agcataccgc atcggtccag atcctcctcc ctagggttac aaccgtcaac ccgctcatga
     2641 cgctccaaga cccacgcatc cagtgctttg ctagcaaccg caactttctc catcacgatg
     2701 tcctcgcact gcccttgagc tggttctgca ccaaacgccg aaacagtcca tcctgtcgct
     2761 ccaactgctc gaaagtgcct tcctgaacga cggtcccctt ctccaagaca attatgtggt
     2821 cagcgtttct gatggtcgat agccggtgcg cgacgaccac gcgggttgca ttcaactgct
     2881 caatcgcccg catgactgct gcctgcgagt tgttgtcgag tgcgctcgtc gcctcgtcta
     2941 atacgaccag ccgaggggca ccggcaatcg ccctcgccag cagcaacagt tgcatctgac
     3001 cgccggagaa tacccctgag tttccactga tgagcgtatt gactcccatg ggaagtgaat
     3061 ccaccaaggc gccgagacca acgaccctca atgccgccag cacctgttct tttcctagat
     3121 tacggccacc cgagatgatc gattggatgc tacccttcgg taggctcaac gcttggagca
     3181 ccacaccgga ccgttcgcgg agagcaacga ggtcaagagt agagatgtcg agaccgtcaa
     3241 aacgaatact ccccgaatcc gcacggatga ggccgagcag cagccgaatc agtgtcgact
     3301 tccccgaccc agaagggcca acgatcgcca caaaagatcc tcgtttgacg gtgaaggaaa
     3361 cctgatcaat cagggtgctt ccatctccag cggcagaata ggtgagccca tcgacttcga
     3421 tgaacccgct aggtccgtcc ggaataactc ccacacctgt cggtgcttct tcggcctcgg
     3481 ccagtttttt cacttcgccg gcgacgtcca gtagaccgga caactgcccg agtgccccgc
     3541 ccagaatgat caggccggca ctcagcaaac tgagtgatac acccgcagca gggacaccca
     3601 aagggttgtg catccattct tgggcatctc ccgtcatcag gaatgcgaca accagaagcg
     3661 caattccgag cagtatcaat cgtctccgga acagctgtcc gcgcagtaca atgcgtctcc
     3721 agtactgttg ccccgcatca tgaacggacc acatcaacga cgctcgctga gacgcaccgg
     3781 ccactcgcaa actcgacacg gagccgagca gtgacgcgga gagcgaattc tgttccgcgc
     3841 gcatcgcacg aagcaccttc tcagctcgcc gacatcttcg ggccgaagtc ccgaacatca
     3901 cgctgatcaa cacacaggtc aaagcgcacc caagcatgga acggggactc acccaagcca
     3961 tagaggaaaa tcccgatagg atcagcccga gcccagcgcc gactccgtag acgagctgaa
     4021 ggatgcggtc ctccgatgcg agcaactccg ctgacatacc cgagcgttca gcgggggaac
     4081 gacgcacaac ttcctcactc tgcccgatga gcagccggtg gaaaacggct gcagaaaatc
     4141 gcgtgcccac aaaactcacg atacgactaa cgagtcgatg cgcgaagagc tcaagaaaag
     4201 cgactccacc cacccagagc agtaacgccc acaccagtcc cacaggcttc gagatgagcg
     4261 ctggatcatg accttcacca cgaaagaact cgagcacaaa gatcggcagc atggccatca
     4321 gtccgagaac cgcccccagc acagcacaca tcaagagcgc aggccactgc cgaaacaaca
     4381 agaatcggag gacacctcca cgaggaagag ccggatagat ctggaaggtt tggtcgatgg
     4441 cgcgatcgat tctctcattc aacggggctc caagcccccc ggtaccctcg tgcacccgga
     4501 agaccccacg gtgacgaatc atcgcgaccc agcgttcctg atcgccgctc atgtgaccga
     4561 gcagtggccc aacgtctccc tcgtaccact tggcatcaag gttgacgcga cggtacccaa
     4621 accccgatgc gcgcgcgcag agggccaacg gatcacgcgt tgcgttgaga gccccaacgg
     4681 gcggaggagt gaaattcgcg ccgacggcgc gacacaccac cgtcaaggcg gaaacaaatg
     4741 acgatgtcag gacattggat gaggccaagt cctgcgagcc ctcacctgag aaccagcact
     4801 gcgactgaac ggtatcacca acgcgatcct ggaaaaccct cagctcaacc tctctccgtg
     4861 tcattgcctc acgtgaaatg gcgagtcggg tctccaacca cgcaaagcag tccggctgca
     4921 gagagttgag ccgatcccaa gtatctctcc tgcacagggc ttccgaggag ccgatcacct
     4981 tccccttcat cttcgagtcg aaccgaagca tgagatgagc cggccacgcc accacatggt
     5041 cgaagacgtg gccccagata acagtgggat gagggagcgt tagccacaag aagcggtgcc
     5101 ggaggacatg cgcctgcccc tccgcgctct tgaaatcagc atcctctgtg ggcacgaaag
     5161 catctgccgc cataaccacg gatgggcatg tagcagccat caatcgagac acccaattct
     5221 ccaacatcat gatgagcatc cgattgggtc cctgctcacg tgcctcacgc gccaacctct
     5281 ccaagtccag cggggccaga cccgtctctg gcagcccgat cgccaccagc ctccactccg
     5341 agccgaccac gcctgctcca atcagtgcat cacccgggcc acaggtgaac agcggctcaa
     5401 gcctgccttg ggccttctgc gcgaagacac gcactcgtcc cttcacgacc agaaacgact
     5461 cgtggccaga ggtcagatcc aagcgatcac gagccgtcag cgctcgtaca agcccatggg
     5521 gcacttcagg cttcatcgtt caccagctcc caataacagc catgcctgtc gatcagttca
     5581 tcatgagttc cttgctcgac gacaactccg ccgtccagga cgacgatgag atcagcgtgg
     5641 cgcactgtcg acaaccggtg agcaatgatc accacggaac acccccgagc cctgatcgtg
     5701 tcgtagatct cgcgctccac gatcgggtcc agtcccgacg tcgcctcgtc aaggataagt
     5761 agggaagggt ccttgacgag cgcgcgagcg attgcaaggc gctgacgttg ccccccactc
     5821 cattctggtc gttccacatc aacctgccga tcgagccctc ctggcttggc gagaatgtcg
     5881 gccaagatac ctgcatcctt ggcggccgcg agcaggactg cgtctggaat cgttgggtcc
     5941 cacagcgcca aattatctcg gacagtcccg cggagcatgg aaccgagctg ctccacgtaa
     6001 gcgactgacc tggtcagcgt cgcacgagcc aactcgtgac gtgctagacc gtcaaacgtc
     6061 actgcgccct gggtaggttc ctcgagacct gcgagcagat gagccaaggt tgactttcct
     6121 gctcctgaac gccccaccac cgcaacatgt tctcccggag ccacagaaaa cgtcacgtct
     6181 ttcaagagcc aagtttgatg atccaccagt aaccccagac ccgacacttt cacggcgcca
     6241 gacagcggtt cggccgtccg atctcctgag atcatcgtca catcttggtc aacgtcttcc
     6301 agtcgagcat gcggtcctac gtcccgcgcc agcgccaaac tgggcgacat tcccgcaaag
     6361 ccggcaatgg aagtcacgca accctgcgcg gccagaacgg ccaggagaag aagcagttgc
     6421 atctgaaaca tctcacccac cggaatctgc cctgccaaga ttccaagagc ggctacccat
     6481 gtcaccatca aactccctgc ccccacgaat gcaataggca tcgcaaaata gaggagactg
     6541 accatctgtg cacgactggt gtcggaactc atggcagcca tcgcgccggt ccaacgcccg
     6601 tagatatttc cttcatcgcc attcgcccgt atgcgctcca gatcatagaa cgcggcggcc
     6661 gcaccgccgg cttgattcga caccgcaata acccgtcggt tcatgaccgg ctcggcccag
     6721 cggccaacac cagcaaccac gacgccccat agcaggacca gagcaacaat cacggcacct
     6781 atctgggggt taacaagtac gctggtcgcc aacgctccga acagtatgag gagctccccg
     6841 aaaagggtcc ccaggttgac cacaacggaa acgatcaacg actcgaagga ctggatctgt
     6901 gaagccagca caccgcggtg cctgagccgg aaaaaactca tcggaagcag catgatcctc
     6961 ccgaaaagcg accgcgcttc atcacacgat cggtacaccg cactgagcac caatgcccgg
     7021 tcacgcgccc acagcaccaa cgcaaccacc accgcactca agatggcgag ggcagacagc
     7081 acgtcggtgg gaagcctccg tgacgtcaac gatccgtaga gaccgttgac gaacacccga
     7141 agcagttgtg ggatggccat cagggcaagt gctccgactc ctcccgccac gagcgccaaa
     7201 gccaagtttc tccgctctgg tgcgatgatg cgcgccagtt cctttaacac ggagggcctc
     7261 tgccccgtct gcgtgaaccc ttcccccggg gtcagctcaa gggcgatgcc cgtgaaagct
     7321 aggtcaaatt cctcccacga catagtgcgc tgaccaaagc ccgggtcgtt aacgacgacg
     7381 cctcgttttg ttccgcggac cagcaccata aaatgcctga attccatgta cacgatcaag
     7441 gggaacctca agtcccccag attttcgggt tcagagcgca tgccgcgcgc ctcgagccca
     7501 aacgaacgag cggctttcag aatcgctgcg gccgagaccc catcccgccc cacattgcac
     7561 acagcacgcg actgggcgag cgagacccac ttcccatagt aagccaacac catgcttaaa
     7621 catgctgccc cgcactcaac cacttcctgc tgcaggagaa ccggaacgcg gagagacccc
     7681 gtgacgaacg gcgcgactct cgggtcacga ctcatcatca aacaacacct cgtaaggatg
     7741 gaacaggtcg aggacaatct ggacttgggc gggagctcct cgcaacagtc tcagaccctc
     7801 aggcgcaccg ccatgggtcc attcaaagcc ctcggggcca gtcccgtcca agagccgaat
     7861 ctcgacaagg tatcccggag ctccacgcgt cacatccgga accagctcct cggctcccag
     7921 aagttgcacc agccgctcgc gacccacggg aacggaatca atcgactcga cacgtccccg
     7981 caggcgcccg aagcggcttg cgggaaatcc actgagtgac acagtggctt ccatccccgt
     8041 tcgaagttgt tgcgcttcca cgatggacac caacgcatac gcctgctgtc tacccgaatc
     8101 gtcaggactg aagaaactac ggtccgaggt gatactgacg actagtgttg aatacacagc
     8161 ccacagcaat gaacccgcca caatcaggca tgcgcccacg aaagcaagcc agccacgcaa
     8221 gggcgagatc gacatcttct tggtcgtcgg gtcagccacc cgcgccttcg tcaacgcctt
     8281 caaacggaaa ccagccacgc taggtcagcc ccgttctccg gaccgcccgt aaccccaagc
     8341 cgccaaggca gtcacgccta cgacccagcc gataatgacc acccacgcca tgagaggcca
     8401 ttgaacatca agcatcgctg acagcgaggc ctgcgcaatc cagtaggacg gaaacaactg
     8461 cccaatatga tccatgatgg ttcccgaagt gaacggaaac cacatcccac ccaaaaaacc
     8521 gaagaatgca ccagcgccac ccagcgcggg acccatcgca tcagtggaaa gaatgaggcc
     8581 gagcgcaata ccgagaatcg cgaatgggag cacgcctacc aatatcagtc cggacatcac
     8641 gacccatctg ccgatgccct ccacacgggc tccgagcagc actccggtta ggtagatgag
     8701 caacatgctg agggcactca tcaaatatgc agtaacgact ttagcgaaca tgtattggga
     8761 agaactaagc ggcgtcaggt gcaactggcg atcccactcg gaagagcgct ccgtggagat
     8821 ccgagcaccg ccggacagcg ccgccatgag agcaccgtat ccggccatgc tcgccatgta
     8881 gtagataatg acgggaatgt cgtgggttcc gatagggatc ttcgactccc ccatcgtcaa
     8941 ggcgaagacc gcgaacaacg cgatagggaa gatcagcgag aagaagaaga acggcttatt
     9001 ccgccacagc ctcagcagct cgtagccaat gtattggaac ttcatgacgt actcccgtcg
     9061 ttattattca gagcaccccg cacttgcgca ctatttccgg acgtgatcgc caggaatgcc
     9121 tcctccaacc cacgctgcgc gacctcgatg cctcgcgcat ctggcgccac tctcagcaac
     9181 tcccgaaggg ccagatccga gtcggagcag tcaagttgca gtctcccatc aacaaaactc
     9241 gcagactgca ccccgtccat tccggcgaag cgtgcaacct cgcgagaatc caccacggca
     9301 tggatgatcc ttccacccgc catggccttg atggccgagg gcggcccatc ggccacgatc
     9361 ttgccagcca cgataacgac cacccggtcc gcgtacatgt cggcctccgc caagtagtgt
     9421 gaggcgaaga gcgcggtcat cccgcggtct tccaaggtcg tcatggtggc ccagaagtct
     9481 tcacgcccct ggacatccat ggccgcagtg ggttcatcga gcacgatcag ggacggagaa
     9541 ctgaccagcg cgatcgcgaa tcgaactcgc tgtgcttcgc caccggacaa gtgggtagct
     9601 cgctttcgcg catgctgact gacgtgcgcg atctccatgg cggcttccac ggacatggaa
     9661 ttcgggaaca gacacgcgac catggacagg agctcgcgga ccgtgagatc tccgatgagc
     9721 ccaccatttt gcaacatggc accaatccgg ccattacgaa cagccgctcg cgggtcttca
     9781 ccatcgattc tgacctcccc ccggtcaggg cgcgtcaagc cgagcagcat gtcgatcgtc
     9841 gtcgacttcc ctgcaccatt cgggccgagc aaggcgacgc gttgaccggc gagaatagtc
     9901 aacgacagcc cttggacggc atgaacgaca ccccctgccg tcttgaacga cttttctaac
     9961 cctatcaact ctacggcatt taccatgagt caacctccaa tcatagcatt tctgctgatt
    10021 caataaccgg ttcagcgtct ttcaacggat tcgcaccgcc atgccaaatc gccaacgcgt
    10081 aggcggggaa tcggaaacga tctgacacat ccccagagcg caacgagcgt ctctcctcac
    10141 ctattccttc cgcaaccggc agaacactcg cacctatcag cacggtttcg accgtcgggc
    10201 tcagttccac gacgcagggc accacctctc tcagactaga acggatcgta aggcgcgcaa
    10261 cacggtcaat ccccatcgcc cctgccagct ccacatctgg cgccaagctt tgcagggtga
    10321 gagcaagatg ccccaaagct cgctccccag gatcaccgtg aacaaaacgc ttcaaaagcg
    10381 cttggaaatg ggcctgttcc ggcagaccac tctccccgat catcgagagc gcgcgctgag
    10441 agtggggagg ctggaagccc gctatcgttc tctcgaaatc ctccaagagg gcaccgacga
    10501 ctggatctcc aaggcttcct ccatacattt cttctgttag cagatcaaga atgcgtgaat
    10561 actttagttt cataaccttt gcaacatagg tgattgttgc acggaaaaga catttccaaa
    10621 aaagattcat ccccatgatg agacgcatgc cacgcttcca gttctcccta tcaagcgtgg
    10681 aatgagccac caccatctcg cccgtcaaag ccggcgtggt caaatcggag ggaatgggct
    10741 ccgtctccat ggcgtatgcc tcacgcatct ctggcgagaa gaattccgtg tttggaagca
    10801 gaagaagcgg ataggcaacc gggcacccac cggcattcag acacgtatca atatcatcta
    10861 ggagagtctc gtaggtctgc cccgggagcc cccagatgag gtctgtgtat gtcgcgatgt
    10921 tacatgaacg cagacgagcg agcagatcgc gataagcggg cggtttgatg tttattcgct
    10981 tggcctttcg catgacggac cgatcaaacg attgcaccga gacggtgact cctccaagca
    11041 gaccggctga gtagagtatg cgggccgcct ctaaagtcgc ttcacggggc tttttcgtcc
    11101 agttcgtgtt gaatgtgatg gtctttttat atcgctcgca ggcctccacc ataagccgcg
    11161 ccaaatcgag atcgcgttcc aagatgccga aatttgcgtc cgcgagaaaa aacaccatgt
    11221 gcggacgaca atgcgcgaca atgaaatcga gttcgcgttc gatgcgttcc aaggagaagc
    11281 atcgaattgc ggttcgcgtc gccccacccc agaagcaata ggcgcaggaa tacgggcatc
    11341 ccctgttgga ctcgtagact aagagcgtag cctccgacag cgattttggg tcaaccaccc
    11401 cagtcaagaa cggggaggca atcgagtcca gatccgcgat caaagcccgc cgtggcgtgg
    11461 tctgcacctc accatgcgcg cgataactga tgccgtgcac ctccccccaa ggacgatcgt
    11521 gctcaatcgc gtgaagcagc tctggcatcg tagactcggc ttccccattg acgatgaaat
    11581 ccagtggtga gccatccgcg agtaacacat ctccctgaaa gctgacatcg cttcctccga
    11641 ggacaacctt cacatctggc catttctgct tgatgacccg tgcacattcc aacgacggtc
    11701 gacggttcca gaaactaacc gagaaaccga cgacatccgg gacccgcccg cgtcccaagg
    11761 atgcgatgac ctcatccacc ccggaagccg ggtcgaacgg ggcgagctga tgcacctcct
    11821 gagtcacgct ccaagatgtg ccaacaatcg gatccgcttg acagacagca ctcaagtacc
    11881 ccaatgccgc gctgtaggtg taaccctggg tgggcgtcaa ctcgaacagc ctgcatgtct
    11941 tggacgtccc gaaatccctc atcaatggtc ctgttcgcct gcgaactcca agtcgaattc
    12001 aggcatgata tgggtagaga aaagttccaa ctgtcgaatc gcttcctcag caggcatcgg
    12061 ccgccatgca agatgccaaa caagatactc cacaggaaac tcgttcaaag ttttttcgac
    12121 accacgcttg acgtcatcga cgctcccgag gatagacatt ccggctcccg ccaaacgttc
    12181 agagacgagc tcaccgggct tcggaacctc tccttcctcg tcgggcagac ggaaaagctc
    12241 aagataacgg aaatacctat accagtgatt ccaaatgaga tcgtcgtatt tctgggatgc
    12301 cgccaaagct gcaccccggt cctcagcgat gtggaagacc cgaataagtc ccatgccatc
    12361 acccagttgc agcttcctgc ctacctcgcc cgcctgcctc cgatagtatt ccccaagcgc
    12421 acgacacgca gcgagggatg ggaactggat aatgggagtc acaccttcgc gggcgcacca
    12481 tccgatcgta cgcgggctta tggagtgcgc ctggaacagc ggaggatgag gcttctggta
    12541 tgggcgcggg acaacagaaa cacccttgac ctgcccattc gaatcgactt cacccggaac
    12601 tccgtaggtg tctgtcatcc cctgagcggg ctgccatggg ggtgtctcct cacgactcgc
    12661 cggaatccga taataggtgc ccggatactt cgcaaggtcc caagtccaag ccatcttcag
    12721 gatccgatag tgttcccgga acaacgacca attaagatta tccctttcct tatcgccgtg
    12781 atccgatcca cccacaccga ttctttgacc caaaacgtca caccaacgac tctgataccc
    12841 acgggccaac cccacgaaaa accgaccttg gagcatctgg tcaatcatcg cagtacgctc
    12901 tgcgagcctc actgggtcat gcgtgggcag cacataccca agctgcccat gatgaagccg
    12961 cttcgtcgca gtgccagccc acagattgta caggccaggg tcaggggaca gctcaactcc
    13021 ttcggaatgg aaatgatgct cggtgtgcga aattccccag taccccaagg catcagcggc
    13081 gactgccaag gcccgcatct cctccaaaag tcgctggaac atctcagtgt tgcgaccgat
    13141 cggacgatac tttgccattt ccttcaaatt tccaactgtg ggatacgttt gaataataac
    13201 cttggtcatg tcagctcctc tgctttgaga ttgattctgt ataattcttt tcgtggagag
    13261 tcgagtaccc aaccgctgca acgtcaacca ccgtcatcgc cattgcagtc cccgcattga
    13321 ccatcgctga atgcgccctt tccgacaccg cagcttgagt gaactcagga tcatgattct
    13381 tggctggcca gcagccgatg ttgaagtatg ggtgaaggca ggggatacgc agcgagaggg
    13441 ctccgagatc cgttgccgcc gggaacggta ccgcttgact cgtcattccc agcgccgcgc
    13501 ggttgccccg ccagaggcgc gccaagccga cgttctgccg cattgcaggc atgaagcgct
    13561 gggccaaaga acactcgatt ttggtacggg ttatcgttgc gacagccccg caggtggtcg
    13621 caagcgcctc cgcagccgcc tggagatgag cgtcctccca agcgcgcagg atgacgtccg
    13681 ctttgagacg acgcgcatgc acagccgctg agccggatgt ggacagaacc tcccagtcaa
    13741 ttatcgctcc acgcggcagc tgccggggta gcagcccgag acccgtagcc agtacatgcc
    13801 acgcctcaga aaccgtgacg cccgaactat aggccgaact atggcctgac gccgcgcttt
    13861 caatacccac ttggtacctc gccaaagcag ccatccgtgg tgcgtcgact ccgctcggag
    13921 cggggtgagc catcatggcg aaattcaccc cgtcgaaggc accgctctcc gccagctcaa
    13981 ccttggctgc accgaactcc tcagaaggag tcccgaacag cgtcaccttc aggtcgattt
    14041 gatccgccac acgcatcaag agcatgaagg ctgcaagact tgcgccactc acaagattgt
    14101 gcccgcacgc gtggccaata cccggaagcg catcatactc ggccatcacc gcaacatgta
    14161 aactacccgt ccccgtggta gcgctcatac cagtctcata cggtccaagg ccttgagtga
    14221 cttgacagcc gagccgtgac gcagcctcga tcatgcgatc gcgactccca tactcggcac
    14281 cagccacctc agccagctta tgaatcgcgc ggctaacctg gccacattct gtacgcacca
    14341 ctgcgcgatc agcaatcagt tcagacttta accgtcccac gtcagtgctg ggcaggttgt
    14401 tcaaacatgg cgccctattc acggaagctc acaacgtcgt gcgaatccgg aatcgatcca
    14461 agaatgacct ctccaacggt cgtttcttcg aaatagtcgc tccccaagat gtcggccaca
    14521 acgtcagagt cgcctccacc gacaggacac gacgcgaggc ccagatccgt cgcgtgaagg
    14581 gtcagtgcgt ggtagagcac cccgacgttc ttgaggatca cagcgtagga cacaccctcg
    14641 tacttccaca taacgcgagg aaaccgagca gtgatcagga gaaccacttg cggaaggttc
    14701 tcaaggagag tcgtgtgtcc catcagtccg gcaagcttgg acacacgctc gtcgaaatcg
    14761 gacactcttt ccagctcgtg actctcgcta cggtagtgat aaaccccggg ttcaagacct
    14821 gcgcagttcg tgacgagggg atagatctcc agttcgtaga gcgaccctcc agatggatag
    14881 ggacggctca acacatcgcc attctcaccg tcagaccgca ccgctcttgt acgttggact
    14941 cgatacaata gtgccgcaag ctggtccagc gtgagcgggc ggtgggggtc ttgttgcctg
    15001 atggagcggc gggattccga tgctgcgacc aaggacaggc ttctttccat gtccgggacc
    15061 gtgagagaga tccgctctcc cccacgccct ggtggtagac cagacgccgg atcagtgatc
    15121 cctttgaaat ggtaggttcc cccgtagcca cccacagagc gccccaccct agtccgagcg
    15181 tggaacagca tctcccacgg tgcccataaa gcgggtccct cctgaggctc cgtagacagg
    15241 aagcccactt caaacaacat gcccaatatt tcagccacga cagccgattc tagtccggga
    15301 atagcttccc gcaattccga gatcgaggat ccctttgcag tcaggtacag aagttctaag
    15361 gcccactttg attggatcgc tgcaatgtat cgcacatcgc cagcctccat gatgatcccg
    15421 cctttttcca ctgcaaacat cacgctgcgc ttgagataca acatcgtctc caggccgact
    15481 gactcctgag ccccgaaacc gaggcgaccc ggcgcaggag caatgggctc caagtttatc
    15541 actcgttcga actctccctt ttcatccacc ccggcacatt cctgtcgcaa ccacccagcc
    15601 acggagagcg ccctcagcag ggatcgcgca tacgccagca cgggaagccc gtgcccagcg
    15661 acttctgtca acgccaattg ggcgtccaca gggccatcca aaagagactt ccagaaggat
    15721 ttcatcgcct cgcggtgcgc atcacccact cgcaagctcc gccctcggaa tgagaatcca
    15781 cgcacatcat tctctggacc tgcattccgg tgatcccaga ccagttgaaa agtcctcatt
    15841 gaaacctacc ttctgaaact catcggacat tcaaggagtg gaccaagaaa cgaatcagca
    15901 ccccgtcaga aatacaccgt cctaggatta agctcatcct ccgagtgaga cttagccaga
    15961 tagcccattg ccactggcac ctcgtacaga cgtcgcggtc cgagacgtcg ccagaagtga
    16021 caaagcccgg gaacaatgac tctagccacg gcaacatcca cctcagggcg actcaaatcc
    16081 atcacataca tcctgctacc caaccgttcc gcgatatcct tgcacacttg gatgtccttg
    16141 aggcagtcat cggtacgtag gccgtggatc tgatccaagc gggtgaatgg taatgtctcc
    16201 gaagggagga gataaggatc tgatgacaca gtggcattct ggaaccagtc caccgcctcc
    16261 ggctctacac ctctatatcg agtcacacca ttttcatctc ttgacaccca aggcaaaaac
    16321 tgattcaact catccaaagc cgcatccaag gcgagcttgg gatcaagatc acagccgaat
    16381 gaaacgatga tgtcttcggg agagccgtcg agccgtgccg acaacagggc aaagcacgga
    16441 atcgaggagt cggtggtgag atccagcgcc cagacctcgc gccccatacg cttatgttcc
    16501 tgccgaaggg ccatcaggta ggaatcatcg atactatcaa ggtccaatcc aggacaacga
    16561 actcgattgt accaccagat gccaacggag tcccgctcga tcagttcgct gaatccactg
    16621 acaatcgctt cctccaacac tcctccagct gccgacccat tggagtccgc caaacaatag
    16681 cacctcgagt agaggtccgg gtgaccgtaa tagcagtagg aagccggcac aagcctattg
    16741 ggcccactcc ccacatcttt aacccagcac cagtcgatga cagcatcagg gtcaatccgg
    16801 tttggaatga aggcgtattt gctgggatta ccctcgttta aagcaattct gttcaaatac
    16861 tgatggtcag agaaaccgag caacagggag ggttcgatcg ccgaatccgc cacttcccga
    16921 taagtggctg tgacgacagg ctcatcacca gtgtacatgg tcaaaccacg ttcaaccgcc
    16981 tcacacaagg cgctgacctc tgcctgccgg ggagttctac ccttcccgcc agagaggcta
    17041 ccgcgcagcg tcttcacgag aagactaaag tcggtgcggg aaggtgcaaa gtcatgtccc
    17101 gccgcagccg agaagtagag atcactatca gagtcgattg gcgtcagttt ggtgataacg
    17161 cctgaatagg gggagatgtg tcgctcaagc gattcacgcg tctcggacaa cgacttgacg
    17221 cgtttcaagg gccgacccga gtcatcccgg cctttgggcc gtgagacgag ctcaaatcca
    17281 atcggatcaa ctcgcgtgtc accgcacacc ggacactgag gccgcttcgt gacaacgtgg
    17341 ctctgtacag cgaactccgg aagctcgata ctgagtagat ctgatggacc acctgcgacc
    17401 aatcggagca gggcggcgga gagcgcaagg gtaatcgatg tagccactcc agattggagg
    17461 ttccccactg gtacacgacg ccctgtctcc agctccgcgt acttttccag gatccgatgc
    17521 cccttcaatc gttgagagag acaggcccag caagccgcac cttcttcacg accgaataca
    17581 ggacctatcc agatctcatc ggtgaaaggc ttaacgagcg cccactcgcg atcaagcttg
    17641 agcattaccc gatttatctc agcaagttcc tcagcaaggt agtccggggt tatgaccagc
    17701 aagggtgatt cgccaccttc agcgagccca agggatttta gctccacgcg gcgccattca
    17761 cggcatatct gatccagcgc tgcctcgcac agctttctcg tttgctccgc caacccaagc
    17821 atcatgactg caaccccacc aatgggagag tccacgccga tggaatccaa gaacgcaccc
    17881 tccgcgccga cggacacggc agggccatcg gcgatgaaac ctactgcttc cagcatcatc
    17941 acaatccgca ccacgagcgc cggactcatc acccccttag tgccgcgcca gatttcagtc
    18001 atacggtgct caccgtcaag cagcgatgcc aagacgcgca tgtgagccat ctcaagagca
    18061 aggaatcgtg tccccgaaac cgccagcatc cgcccgttcc cgagttcgac caagtccacg
    18121 ttcgcccgga ggcgaggacg catgcgcatc acccgcgcaa ccttgtcgga ctccgaaact
    18181 tcaccaatca caataaccct cttaacgtga gcatgacagg ccagatggca aaaccaactc
    18241 tgggactgcc tcatttatgc aacacaacta catcggcctg agaatcgatc gcctcgctgc
    18301 attcacactc atgcgtcgag ccctcatcac ctctagccaa aatgaaaaat taaaattgag
    18361 tgggaaatcc caattctcac ccaaaaaggt atacacaatt tacgatagcc gaggggcgaa
    18421 atcccctcgg ctatccgcga atatcaggcg gtgcaggtgc agcagggggt acaggagcaa
    18481 cagtaacttg taccgccggg catctcggcc aactcggcct cggtcagctc gccgagatca
    18541 cccaagtcaa ccgggggcac ctcggggacg acaaccgtca ctgcaccggc ttctataccc
    18601 tcattccaca tgcggtactg atcgctgaga tccccatcac ccgcgatagc gcggaggacc
    18661 gtgagctcca ccccatcggg aaccttgaaa ccgacttcac gaagagccgg cacagggttt
    18721 gccatcatct ccatcgtgta gtcctcgctc gtccacgctc gcgtgagaag agcatagtag
    18781 gcgtcctcga actctttgaa ttccatgctc atcggcttcc tctctgtagg tttccacaat
    18841 gcgaccatcc cgcctgccgg gacaactctg tcattgcctg ttttcaggct acatcacgcg
    18901 agttccttga tgtcaagttt acttgaagtg ttgacaattt ttgcttgggt aggctgcttt
    18961 tcaagtcttg acctcagctc gaacagagca accagtcaag acctgtggac tggcatgtgg
    19021 cgcgagcgtc acctcctgat tggtgctcgg tgcgctcggc caagacgccc ttctcgaact
    19081 tcgctccagc tcgaaccagc gcgacgaggt gagatgtgtt gacgtgcgcc gcctggccta
    19141 ggggctcgat gagcttgtac gccatcgcga tgccggcgac ccctgggaat cttcggcgac
    19201 ttgttgccga agctggacga tggggaaggc cgactcgatc ggattggtga tccacagtgg
    19261 agtcagcgct cacccgggta gttgtggaag gctgacaaca cgtcaaggtc gtcggtgatc
    19321 ttcgcagcca tttcgggaac gtcgccccat acccgccggc ggacgctgtt gctgcggcta
    19381 gtgttgtcct cggtgttcca gttctctgcc agtgcggcct tcgcgccggg atgcgcggac
    19441 ttcagcagcg cgtcaagcag gttggcgatc ttatggaacc agcaccgcaa ctcacggatc
    19501 tggggggcac accttgcagc gccttccaga atcccagtgc gccgtcgccg accgtgagga
    19561 cgggagcata atgccgcggc gcttgcagtc acgcagcaag ccggcccacg actcggtgga
    19621 ctcgccgaac ccgccgctta gggtgatgag ttccttggtg cagtcacacg cccgccgatc
    19681 atgaccagca gacacacctt agccggcctc gaggcgaacc gtgaggtgga tcctgtcgac
    19741 ccacaggtag acgtagtcgg actctgccgg cgaccgctga gcgaatgtct tggcgtcgcc
    19801 ttatcactgg gcgatcagcc ggttgatggt ccagggcctc ggtaaagtcc ttcgttctct
    19861 gtgttgacta ggagttttgt tagtggagtg gtcgtagagg gtctctggag tggtgtttga
    19921 gggctgtggt gatgttgaca gttccggtca ggcgatggag gctgatcgcg gtgttgcgca
    19981 gtgtggtcat cagggtgggg ccgtgcccgg tgtggagctg gtgacggtcc tcgtcgaagg
    20041 tcacatccct gacccagtgc agccggttct tgatacccca atggctctgg atgaggtcag
    20101 cggggctggt ctggtgggca tcgagggatg tgatcaggta gaccaccccc cacacggtct
    20161 tgcggccgtc gatggtgcga gtacggcgca actgtgcgac ctgacgggca cccggccagt
    20221 cgatccggtc agggacctga cagaccttga tcgtgcgcct cacgcgccgg ccatgaccag
    20281 tggtcgtgct gtggtgggcg gggatgttct tccaggtgca aggttttgag cgcggtccgc
    20341 aggcgggcct gtatgccttt caccgtcagt cagcgcgtag tcatgaccct gcccggtaag
    20401 ggtacaggca gtgaagcggt gcaacgcgtc agtggtgaca acgatcttgt tgcgtggcag
    20461 ggattccagc agaaccggta gggcggcgat ctcgccggtc ttcgcgagga ggctggtgtt
    20521 gcccggccac gatcccgccg cgggtgacag cggccagcag atgcgacgct gccatgtcac
    20581 gagattttcg ctccacgcag gcttttgccg tcaaccacca ccatgcgacc cttccatcga
    20641 gtggcgtcac gggccagcca cgccccgacc atcgcggaca gttcatcagg gtcgaggact
    20701 tggaggatcc ggcggatcgt ggattccgac gctactcgac accccaggcg cagcagcccc
    20761 gacttggcca ggagatcacg gccgacatca gcggcccact cggcgaccgc gaccaggccg
    20821 cccgcaccgg cacacaccac cgctgtggcg atggcaagaa ccccggccag gtcgtagcag
    20881 cgaccacgac gaccccgaag gtcagcgatg gtgacgaaca cacccaacag ccactggccg
    20941 cagacaggta tggtgaggga tgatgagcac acgcgtgggt cctcatgatt tcttggtgat
    21001 gacaaggtgt gtaggaaccc tcaccatccc agaatccgca ggcaccacac ccccatcacc
    21061 cctagccaca ccccagacac cacgactctg ccgaggccct ggttgatggt cgctgcggac
    21121 aggcccgcgg tcgacccgag gagctgcgcc agcgccggca cgaagtcatc gcagggcaag
    21181 ccgtgcagat acagcagcgg tatcaccgcg gccatccctg gcgatttcct ggcccaaacc
    21241 ggcagaatcg caaaggaaaa ccggtaccgc tcgccactct cctcctcgag gcgcttgtcg
    21301 ttagctcgcg gctggcgcac cgggaccgca ccgcacctcc gcggctcgtg gaagccattg
    21361 ctgaccacca gccggtggcc ttactcatcg gccagatgcg cgtgggcctc gacgtgggcg
    21421 gcgaccacgg cctgcagcac cgcagtcaac atctgccgtg cgccttcgca tgccagctca
    21481 tcgagcaaca accagccgcc ggggcatgct tcttggactc gttctcctcg gggaccacct
    21541 tgagcatggg catgccttcc cgagccgacg ctccaacgcc ggccctgatc agagtgcaga
    21601 ttcgctccag atcctgctcg ggagatgcgc ccgcttcaca ccaccccatc aaacaccatc
    21661 caccgatcca gatcattgct cgctcgaggg tagagctggc ggtgaatcag cgcaaggccg
    21721 caacaagaca aaaggcctta gccgaccgcg taaggaaaac agggggtccc gggacgagcg
    21781 gatgggattg accggctggc atcgccacga cgcatgagac gcgctgaagt tgcgtgaggt
    21841 tgaaactcac gcaaaccaca caacagcgaa cctacggaga ggaactccgg ccagccctgg
    21901 tactgcctcg gaccccacag gttaggctta tggcgcagtt cataccggcc ctgagatccc
    21961 gtccaaacga gcaggcacca gttcaagcct ccgcacactg tccgacgcga cccccgcgct
    22021 cggcgggggc cgcgtcggat gattctgctg ctcaggccag gcccttggat ttcagccagt
    22081 cgcccgcgat caccgaggcc gacgccttct cgtcgacgga tcgcttgttc atggcgatca
    22141 ggtcctcggg ggtcagctcc ttcgacacct tgttcagggt ctccgcggtc tggtcgtcca
    22201 ccttcttgga tacgatcggc accacgttgg aggacaggaa caggttcttc gggtcctcca
    22261 gggccaccag gtcgccgtcg gccagcaccg gggcggcggt gtagatgtcg gcgatctgca
    22321 cgtccccgtc gcgcagggcc ttgacggtga gtggtccgcc tgcatcctcg gcgggtttga
    22381 tcgtggcctc gaccccgtag gtctcgcgaa gccccttcgg cccgtagggg cgggactcca
    22441 gctcggagtt gccggcgatc ttcaggtccg gcaccgatgc gagatccccg atctgtttca
    22501 gcgagtactg ctccgcgaac gccttggtca ccacgtagga gtcctggtcg gttgccgacg
    22561 cctgctccag tgccttcagg ccttccggca gggcaccgac cagttccgcg tggacctgct
    22621 ccggggtgcg ggccgtggtc tcgggtttgt agtactgcag cagattgccg ctgtactcgg
    22681 ggaagatgtc gatcttcccg gcctggagtt cgggcatgta gacctcccgc tgtccgatct
    22741 tcagctgccg gtccaccttc ttgcccgact tctccaagga ctgggcgtag atctcggcga
    22801 tgatctcgtt cgagtagtag tcctgcgagc cgatcaccag ggtgtcggag gaattcgtgt
    22861 cgtcgcttct tccctcgatg ttcgaggcgc tgccgcagcc cgccagggcc agggctgctg
    22921 cgattccgag tgcggcgagc ttggtcttgg atgtcatcgg gactccttcg cggaagcgat
    22981 ctgggtactt gggtcgagtt ctcgggtgac caggcgcttg gccaggacca gcagcaggtc
    23041 caggacgaga gccagggcga cgaccagcag cgcgccgccg atcatctgcg cgtagtcgcg
    23101 ggtcttgagg ccggtgaaga ggaaccgccc cagccccacg tcggcggtgt aggcggcgag
    23161 cgtcgccgtg gcgacgacct ggagggtggt cgatcgcagc ccctcgagca gcagcggaac
    23221 ggcggcgggc agctccacct gggtgagcac ctgccacgag gacaggccga tggcgcgggc
    23281 cgcgtccacc gtgaccgggt cggccgaggt gatccccgag taggccccgg cgagcatcgg
    23341 ggggatggcc agcaccagca acgcgcagaa gggagccacc agccccaggc cggaccacag
    23401 gccgaccagc gtcaacaggc cgagggtcgg gagggcgcgg gccgacgcgg tgaccatggg
    23461 aaccaccgcc accccgcgcc gcgtatggcc gatggctacc ccggccggga gcgccaccac
    23521 gcaggccacg gcgaccacgg tgagggtgaa ggcgaggtgt tgcagcagtc gtgacgagat
    23581 gccgctgtcc ccgtcccagt tctcgggtgt gaacagccag ccgagggcgt cgaggaagag
    23641 attcatgccg tcacctgctt ctgtttgcgg acccacgggg tcagggccct gccgagcagc
    23701 acgacgagca gatcgaagat cagggcgagc agcagggtcg caccgagccc ggtcagcagc
    23761 gattcgacca gttgccgctg gaaaccgtcg gtgaacaggg tgccgagcga ctgcaccccg
    23821 accagcgcgc caaccgtgac cagggacacc gtggaggcgg ccaccacgcg cagccccgcg
    23881 atcagcaccg gcacggcgag cggcaactcc atctgccaga atcgccgcca cggatcgacc
    23941 ccgagggcgt tcgcggcctc gacgacctcc tccggcaggg aacgaaatgc ctccgccacc
    24001 tgggtgacca gtaccgagat cccgtacagg gtgaggacta tcaccatgtt cagcggggag
    24061 cgcaccggca cccccaggat gaccgggatc accacgagca tcgggaggga gggaaccgcg
    24121 tacaggagcg agaaggcacc gagcagaagg cctccgaagc gccgggtcgc gaccgccaac
    24181 cgggccagcg gcaccgacag cacggcggcc gcgacgatgg cgctcagcga gagcagggta
    24241 tggatcagga agtagctgcc cacctgcccg aggttgttga tcagccaggt cacgacgact
    24301 ccctgtcccg gtttcccccg ccgtcgtcgg cccggaggga gcccaggggc cgtccctcgg
    24361 cgtcgatcac gagcctggag ccgttgcgtt cgatggttcg cagctgacga cgacccgcat
    24421 ccgccccgac gaaatcggcg acgaactcat cggccgggtt ggagagcagc tcctccgggg
    24481 tgccgacctg cgccaggacg ccgccggtgc gcagcaccgc cacctggtcg ccgaggagga
    24541 aggcctcgtc gacgtcgtgg gtgacgaaca ggatggtggt tcccaggcgt cgctgcaggt
    24601 cgcgcagttc ccgctgcagg tcggcgcgga ccagcggatc gagggcgccg aagggttcgt
    24661 ccatgagcag gaccttgggg tcgttggcga gcgcccgggc gactccgacg cgctgccgct
    24721 gcccaccgga gagctgtgag gggaaacgct cggccaggtc gcggtcgagc ccgaccatgt
    24781 ccatcagctc cagggaacgt tcacgcgccc tggccttggg aaccccgtca aggatcggga
    24841 ccgtggcgat gttgtcgacg acgcggcggt gcgggaacaa cccgccatcc tgcaggacgt
    24901 aaccgatgga gcgccgcagc gccaccgtcg gttgcaccgc gacgtcctcc ccggccagca
    24961 gcacgacgcc cgaggtgggc gtcaccatct tgttgaccat ccgcatcagc gtggtcttgc
    25021 cggatccgga cgagcccagc agcacggtcg tggagtgttc ggcgatgtcg agggtgacgc
    25081 ccccgacccc gacggtaccg tccggataga tctttcgtac gtcctcgaac cggatcatga
    25141 ctcggctccg ttctcgttgg tcagggcgac gaacccgccg ccggggaggg gctcgtcgag
    25201 gcgggcgccc tgcatggccg gaacgacatc ggcccgctga ccggcgccgg cggccacccg
    25261 gatcaggtct cgggtgagca ccaccaactc ctcgtggcgg aaaccggcga gcaccgtgcg
    25321 cagggtgttc tcgaaggttc cggccgcgct ctccatccgc atccgtccct tgtcggtgag
    25381 gctcaggcgg caggagcgcc ggtccctggg gcagggagtc ctgaccacga gcccatcacc
    25441 gaccaggcgg tcgacgagcc gcgaggccgc gccgaccgtg gtgtgctgac gccgggcgat
    25501 gtcctggacc cggggaccgc cctcggccgc tgacgcgtcg atctgtttca ggacgaggta
    25561 acgcgccagg gtggcggagt tcgcggtccg ccagaggtcc ttctcgagcc ggttccacag
    25621 cgccacctcc gcgtgcagga gcgcttcgaa gagggctccg tggtccccga ggggtgctgc
    25681 tgtttccttc acccgggaaa cattacatgt aactcaatta catggaaaac atgtgcgcga
    25741 acgcgagacg gccgaatcac ggagaacagc gacgccggcc gggccgtgag aacccgaccg
    25801 gcgtcgcggg gcgcacccct gtcaggacag cgacccgtag gtcgtcttcg ccttctccag
    25861 cgcggcgacg taccccgcgc gctcgtagac atcggccggg gtgtggctcg gcacggccag
    25921 catcccacgg gcctggtcca gggtgagcct cctgccgtcg agccaggcat cgagcccttc
    25981 gaccaggcgg gtggcgtgcc cgatgccgtg acgcaccagc gccgaggtgg tgcagaccac
    26041 atcggccccg gccagcaggt acttcacgac gtcctccggc tgatccaccc cggacgaggc
    26101 cgcgagcgac gcctccacgt ggtcgtgcag cacggcgatc caggtccgtg gcaggcgggc
    26161 gtccacgggt gagctcagcg tcaccccgct gaccacctcc agtcgttcca ggtcgatgtc
    26221 gggctgcagg aaccggttga acagcaccag tccatcggcc ccggcccggt cgagacgctg
    26281 acacatcgcg ccgaccgacg agaagtacgg gctgagtttc accgcgaccg ggatgtccac
    26341 ctccgacttc acggcccgga ggatgtcgag gtggcgctgc tccacctcat cgcctcccag
    26401 ggcgaaatca cccgagacgt agtagatgtt gagctccagg gccgccgccc ccgcgtcctg
    26461 caggctgcgt gccgagtgca cccaaccccc gcgggaggcg ccgttgaggg atgcgatcag
    26521 cggcacgtcg atggcccggg cgcccttctc gacgagccgc aggtaactcg tgacggcatc
    26581 ggtctcggcc cgtggcacct ccgggaagaa gctggtggcc tccggggtga tgtcggcgaa
    26641 ctgttcctcc agttccacca gccgctccgc gtcgcggaac agctgctcct cgaacaggga
    26701 gaacatggtc acggccccga cccctgcgtc cgccagcgcc ttgatgtcct cgacgttctg
    26761 gctcagcggc ccggccgagg cgacgacggg gttgcgcagt tccaacccca ggtagctgct
    26821 cctcagctct gccatgattc ctccttgcgc gggtcggcgg cgaacttctc cgcgccccgc
    26881 agcgccaact cctcgtactc ggcccagcgc cggtccacct gcgcctgcgc gatgtcgatg
    26941 agacgatccg cctcctccgg gtcggcggcg tgcagcacct tgtagcgcag ctcggcgttc
    27001 tggtactcgc gcagcttcag gcgtggccgg gggctgtcga gcaggaaggg gttgccaccg
    27061 gtttcccgga tcaccgggtt gtaacgcatc agcggccagt gcccggagtt gacggcacgg
    27121 tactgctgct ccagaccctt gcgggtgtcg atgccgtggg cgatgcagtg gctgtaggcg
    27181 atgatcaggc tcggcccctc gtaggcctcc gcctcgcgga acgccttcaa ggtctgctgc
    27241 gggtccgcac ccatcgccac ccgggccacg tacaccgacc cgtaggccat cgcctgcatg
    27301 gccatgtcct tcttgttggt gtgcttgccc gcggacgcga acttcgcgac agcccccagc
    27361 ggggtggatt tggacgcctg gcctcccgtg ttggagtaca cctcggtgtc cagcaccagc
    27421 acattgacgt tgcggcccga ggccagcacg tgatcgacac cggaggaacc gatgtcgtag
    27481 gcccagccat cgccgccgac gatccacacg gaacgccgca gcagatggtc gcagacgctc
    27541 ttgaggtcct cgatcttcgg gccctccagc tccgccagcc gcgccttgag acggtcgacc
    27601 cgggcggcct gccgggccag acccgattcc atgcgctgct tcgcggccag cagcgaatcg
    27661 atcagttcgt cgtcgtcgat ctcggggcgc agctcctcca agaggcggcg cgccatgtcc
    27721 cggtgcaggt cggcggccag ccggagcccg agcccgaact cggcgttgtc ctcgaacagc
    27781 gagttcgacc acgccggccc gcgtccccgg gcgttcttcg cccacggggt ggtgggcagg
    27841 ttgccaccgt agatcgacga gcagccggtg gcgttggcga cggtgacgcg atccccgaac
    27901 agctgggtca gcagcttcag gtacggggtt tcaccgcacc cggcacaggc cccggagaac
    27961 tcgaacaacg gctccaggaa ctgggtgcca cggacggtgc cgaagtccac gttgcggcgg
    28021 tcgttgagcg gaatggtctc gaaaaacctg accgcttcct tctccttttc ccgttccagc
    28081 accggctcca gattgatggc gcgccggttc ggctgcccgg cgggccgcac gggacaggcc
    28141 tccacgcac
//
