LOCUS       NZ_LS483425            41176 bp    DNA     circular CON 13-FEB-2024
DEFINITION  Streptococcus pyogenes strain NCTC13737 chromosome 1, complete
            sequence.
ACCESSION   NZ_LS483425
VERSION     NZ_LS483425.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1
  AUTHORS   Doyle,S.
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUN-2018) WTSI, Pathogen Informatics, Wellcome Trust
            Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 01:17:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,667
            Genes (coding)                    :: 1,613
            CDSs (with protein)               :: 1,613
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 32 of 54
            Pseudo Genes (incomplete)         :: 27 of 54
            Pseudo Genes (internal stop)      :: 25 of 54
            Pseudo Genes (multiple problems)  :: 24 of 54
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:29:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1094137
            Orig. end                         :: 1135313
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LS483425.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41176
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="2"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41176
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41176
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21176](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21176
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            complement(780..1430)
                     /locus_tag="DQN36_RS05550"
                     /old_locus_tag="NCTC13737_01097"
     CDS             complement(780..1430)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /locus_tag="DQN36_RS05550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01097"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_111704235.1"
                     /transl_table=11
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGRS
                     CQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYISE
                     VFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSSLAA
                     MITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            complement(1459..2322)
                     /locus_tag="DQN36_RS05555"
                     /old_locus_tag="NCTC13737_01098"
     CDS             complement(1459..2322)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /locus_tag="DQN36_RS05555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01098"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_002990133.1"
                     /transl_table=11
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWDTIKEKGVLKVATPG
                     TYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLNNF
                     DITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMKVAQ
                     KQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMSDVQY
                     NPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDKKIPVI
                     DTKDVN"
     gene            complement(2440..3894)
                     /locus_tag="DQN36_RS05560"
                     /old_locus_tag="NCTC13737_01099"
     CDS             complement(2440..3894)
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /locus_tag="DQN36_RS05560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01099"
                     /product="amidase"
                     /protein_id="WP_111704236.1"
                     /transl_table=11
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSER
                     FEAALEEAKQRDFSGKPFAGVPIFLKDLGQELKGDLSTSGSKLFKNHHATKTDLFVKRL
                     EALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGISALA
                     TASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTRNLLY
                     YLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALRQAVTWLR
                     EQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMETMTWAIY
                     QSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVPDSKLMAN
                     LAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEGLPMGIQLI
                     AAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            complement(4091..4720)
                     /gene="pyrE"
                     /locus_tag="DQN36_RS05565"
                     /old_locus_tag="NCTC13737_01100"
     CDS             complement(4091..4720)
                     /EC_number="2.4.2.10"
                     /GO_function="GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /locus_tag="DQN36_RS05565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01100"
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="WP_002984920.1"
                     /transl_table=11
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSY
                     PKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDHGA
                     GNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNF
                     KEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            complement(4778..5470)
                     /gene="pyrF"
                     /locus_tag="DQN36_RS05570"
                     /old_locus_tag="NCTC13737_01101"
     CDS             complement(4778..5470)
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /locus_tag="DQN36_RS05570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01101"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_011184421.1"
                     /transl_table=11
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGP
                     DIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGL
                     GQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAI
                     KAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQ
                     AIKAEWAG"
     gene            complement(5747..6283)
                     /locus_tag="DQN36_RS05575"
                     /old_locus_tag="NCTC13737_01103"
     CDS             complement(5747..6283)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /locus_tag="DQN36_RS05575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01103"
                     /product="hypothetical protein"
                     /protein_id="WP_020905099.1"
                     /transl_table=11
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEFP
                     AHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLIDL
                     CQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEEEAF
                     IKYYQSPKIPTGEFE"
     gene            6505..7410
                     /locus_tag="DQN36_RS05580"
                     /old_locus_tag="NCTC13737_01104"
     CDS             6505..7410
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /locus_tag="DQN36_RS05580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01104"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_023079084.1"
                     /transl_table=11
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMGI
                     TIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFVVN
                     AFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDDNHL
                     TASPLFKAQPHIFVSKSNPLATKSLLSMDDLSDFPYLSYDQGIHNSFYFSEEMMSQMPH
                     NKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFIKHEKA
                     NLSKMGERFIEYLLEEVTFD"
     gene            complement(7490..8278)
                     /locus_tag="DQN36_RS05585"
                     /old_locus_tag="NCTC13737_01105"
     CDS             complement(7490..8278)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /locus_tag="DQN36_RS05585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01105"
                     /product="LytR family transcriptional regulator"
                     /protein_id="WP_111704237.1"
                     /transl_table=11
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERRE
                     LNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRSVS
                     PILYRLFLRLITSEIPNFKTYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSRNVT
                     TKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSSQAFL
                     ENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(8271..8984)
                     /gene="deoD"
                     /locus_tag="DQN36_RS05590"
                     /old_locus_tag="NCTC13737_01106"
     CDS             complement(8271..8984)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043096 - purine nucleobase salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="deoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /locus_tag="DQN36_RS05590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01106"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_002990147.1"
                     /transl_table=11
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNM
                     FGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELV
                     LAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNM
                     PERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTF
                     TDMMKVGLETLIAND"
     misc_feature    9356..9369
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.2"
                     /tool="antismash"
     gene            complement(9569..10378)
                     /locus_tag="DQN36_RS05595"
                     /old_locus_tag="NCTC13737_01107"
     CDS             complement(9569..10378)
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /locus_tag="DQN36_RS05595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01107"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_003053715.1"
                     /transl_table=11
                     /translation="MSLMTKINETKDFLVAKGIEAPEFGLILGSGLGELAEEVENPVVI
                     DYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKALG
                     CEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTKVYR
                     NKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVAAHSG
                     LKVLGISAITNFAAGFQSELNHEEVVEVTEHIKEDFKGLVKAILAEL"
     gene            complement(10362..10802)
                     /gene="arsC"
                     /locus_tag="DQN36_RS05600"
                     /old_locus_tag="NCTC13737_01108"
     CDS             complement(10362..10802)
                     /EC_number="1.20.4.1"
                     /GO_function="GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="arsC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /locus_tag="DQN36_RS05600"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01108"
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="WP_038432915.1"
                     /transl_table=11
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLI
                     ELLQSMGISARELLRTNVPEFEAHGLANQAVAEKDVINAMLTDPILINRPIVVTRKGVK
                     LCRPSETLLDILPVPLPSPYIKEDGEIVNPIEAKGEKDVIDD"
     gene            complement(10821..12032)
                     /locus_tag="DQN36_RS05605"
                     /old_locus_tag="NCTC13737_01109"
     CDS             complement(10821..12032)
                     /EC_number="5.4.2.7"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008973 - phosphopentomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /locus_tag="DQN36_RS05605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01109"
                     /product="phosphopentomutase"
                     /protein_id="WP_020905095.1"
                     /transl_table=11
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISET
                     AGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGLNI
                     TEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTS
                     ADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRH
                     DYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTLIKTLQ
                     LPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLLLITADH
                     GNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTAMIGESFL
                     GHLK"
     gene            complement(12109..12792)
                     /gene="rpiA"
                     /locus_tag="DQN36_RS05610"
                     /old_locus_tag="NCTC13737_01110"
     CDS             complement(12109..12792)
                     /EC_number="5.3.1.6"
                     /GO_function="GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /gene="rpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /locus_tag="DQN36_RS05610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01110"
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="WP_002994002.1"
                     /transl_table=11
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEG
                     LQVVGVTTSSVTSKQAEVLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLME
                     KIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDS
                     RLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLE
                     APKAS"
     misc_feature    complement(13026..13039)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.77"
                     /tool="antismash"
     gene            13170..15269
                     /locus_tag="DQN36_RS05615"
                     /old_locus_tag="NCTC13737_01111"
     CDS             13170..15269
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /locus_tag="DQN36_RS05615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01111"
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="WP_111704238.1"
                     /transl_table=11
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEE
                     FQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEIQD
                     TAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSLEAG
                     TQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSR
                     GELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHIT
                     LPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEIAKQKER
                     QEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMG
                     TNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGK
                     TELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRN
                     PYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFGQQDTE
                     TSGSNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLT
                     IADDAKAHLIDLGYNYAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVI
                     RQKDQ"
     gene            complement(15327..16070)
                     /locus_tag="DQN36_RS05620"
                     /old_locus_tag="NCTC13737_01112"
     CDS             complement(15327..16070)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /locus_tag="DQN36_RS05620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01112"
                     /product="hypothetical protein"
                     /protein_id="WP_002984942.1"
                     /transl_table=11
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSSI
                     EGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQVER
                     DIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFEKLA
                     SQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFDYTRF
                     GKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(16218..16817)
                     /gene="yihA"
                     /locus_tag="DQN36_RS05625"
                     /old_locus_tag="NCTC13737_01113"
     CDS             complement(16218..16817)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yihA"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /locus_tag="DQN36_RS05625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01113"
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="WP_011184414.1"
                     /transl_table=11
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSF
                     INTILGRKNLARTSSKPGKTQLLNFFNIDNKLRFVDVPGYGYAKVSKSERAKWGKMIEE
                     YLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHES
                     VVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            complement(16827..18056)
                     /gene="clpX"
                     /locus_tag="DQN36_RS05630"
                     /old_locus_tag="NCTC13737_01114"
     CDS             complement(16827..18056)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /locus_tag="DQN36_RS05630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01114"
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="WP_023609877.1"
                     /transl_table=11
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEI
                     IKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDD
                     DDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLK
                     LIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVP
                     PQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASY
                     MQEIISEDIQKFGLIPEFIGRLPVVAALEQLKISDLIRILTEPRNALVKQYQALLSYDG
                     VELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVE
                     GKSKPVLETA"
     gene            complement(18186..18356)
                     /locus_tag="DQN36_RS05635"
                     /old_locus_tag="NCTC13737_01115"
     CDS             complement(18186..18356)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /locus_tag="DQN36_RS05635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01115"
                     /product="hypothetical protein"
                     /protein_id="WP_002990165.1"
                     /transl_table=11
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLGSLFLLNAFTNLV
                     NSIHAFYGTLF"
     gene            complement(18376..18873)
                     /locus_tag="DQN36_RS05640"
                     /old_locus_tag="NCTC13737_01116"
     CDS             complement(18376..18873)
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005542 - folic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /locus_tag="DQN36_RS05640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01116"
                     /product="dihydrofolate reductase"
                     /protein_id="WP_002984955.1"
                     /transl_table=11
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAILM
                     GRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGGNK
                     VLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVTALK
                     HK"
     gene            complement(18953..19792)
                     /locus_tag="DQN36_RS05645"
                     /old_locus_tag="NCTC13737_01117"
     CDS             complement(18953..19792)
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /locus_tag="DQN36_RS05645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01117"
                     /product="thymidylate synthase"
                     /protein_id="WP_011017679.1"
                     /transl_table=11
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFA
                     EYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRT
                     IGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVR
                     RVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYD
                     NQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI"
     misc_feature    complement(19748..19762)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.77"
                     /tool="antismash"
     gene            20001..21176
                     /locus_tag="DQN36_RS05650"
                     /old_locus_tag="NCTC13737_01118"
     CDS             20001..21176
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /locus_tag="DQN36_RS05650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01118"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_023609855.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 4.3e-07,
                     bitscore: 26.2, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSVA
                     PITEDIITLAASAADQILTDEDRSKIDMVILATESSTDQSKASAIYVHHLVGIQPFARS
                     FEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIALLVT
                     ANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQKRENL
                     QLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGNIYTGS
                     LYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQTLLDQRT
                     RLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHRRIYHTNDKN"
     gene            21163..22440
                     /locus_tag="DQN36_RS05655"
                     /old_locus_tag="NCTC13737_01119"
     CDS             21163..22440
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_process="GO:0016054 - organic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /locus_tag="DQN36_RS05655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01119"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_020833420.1"
                     /transl_table=11
                     /translation="MTKTNLNWSGFSKKTFEERLRLIEKFKLLNAENLNQLKTDVLLPI
                     QTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSGGF
                     KAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTIHLE
                     EKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESLVTTS
                     CEIPVRLLDHDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIATGNDWR
                     AIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPTVSIAHD
                     LLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGATQDEIAP
                     LVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(22670..23659)
                     /gene="fni"
                     /locus_tag="DQN36_RS05660"
                     /old_locus_tag="NCTC13737_01120"
     CDS             complement(22670..23659)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /locus_tag="DQN36_RS05660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01120"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_010922169.1"
                     /transl_table=11
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLSTH
                     FAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRL
                     HEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTWKKH
                     LAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRGGDRS
                     YLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVE
                     KYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(23646..24659)
                     /locus_tag="DQN36_RS05665"
                     /old_locus_tag="NCTC13737_01121"
     CDS             complement(23646..24659)
                     /EC_number="2.7.4.2"
                     /GO_function="GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /locus_tag="DQN36_RS05665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01121"
                     /product="phosphomevalonate kinase"
                     /protein_id="WP_023609882.1"
                     /transl_table=11
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAH
                     IQLASDMFSHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKF
                     GIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVA
                     YTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQV
                     TASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHSAIYHPKLVTLVA
                     ACQKQDAVAKSSGSGGGDCGIALAFNQNARDTLISKWQEADIALLYQERWGENDQP"
     gene            complement(24652..25596)
                     /gene="mvaD"
                     /locus_tag="DQN36_RS05670"
                     /old_locus_tag="NCTC13737_01122"
     CDS             complement(24652..25596)
                     /EC_number="4.1.1.33"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /locus_tag="DQN36_RS05670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01122"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_014407503.1"
                     /transl_table=11
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFTT
                     TSVSFLPDTATSDQFYINGVLQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAAGL
                     SSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAIYKV
                     ETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDQWVEQSAIDYQHMLTYLKTNNF
                     EKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMDAGPNV
                     KVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            complement(25578..26456)
                     /gene="mvk"
                     /locus_tag="DQN36_RS05675"
                     /old_locus_tag="NCTC13737_01123"
     CDS             complement(25578..26456)
                     /EC_number="2.7.1.36"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /locus_tag="DQN36_RS05675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01123"
                     /product="mevalonate kinase"
                     /protein_id="WP_002984974.1"
                     /transl_table=11
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFPA
                     DKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRAVF
                     SYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIALNGY
                     LIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQLMTQA
                     HSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKISHRLKE
                     EGAVNTWIQML"
     gene            complement(26750..27982)
                     /locus_tag="DQN36_RS05680"
                     /old_locus_tag="NCTC13737_01124"
     CDS             complement(26750..27982)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /locus_tag="DQN36_RS05680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01124"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_002993949.1"
                     /transl_table=11
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRILH
                     LISSNKGKLPDTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDREE
                     AQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLAVSM
                     MLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNELVEL
                     MTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAEDFKSLV
                     LKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIGRRRKRA
                     KLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFKGTITVNY
                     KNDAIVFTVVI"
     gene            complement(27991..28659)
                     /locus_tag="DQN36_RS05685"
                     /old_locus_tag="NCTC13737_01125"
     CDS             complement(27991..28659)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /locus_tag="DQN36_RS05685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01125"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002984985.1"
                     /transl_table=11
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAY
                     DIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFS
                     LKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLN
                     QGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
                     "
     gene            complement(28662..29312)
                     /locus_tag="DQN36_RS05690"
                     /old_locus_tag="NCTC13737_01126"
     CDS             complement(28662..29312)
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /locus_tag="DQN36_RS05690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01126"
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="WP_011184405.1"
                     /transl_table=11
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGF
                     KLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVDLL
                     KSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGKKKGCYFIEVQLRTIAQD
                     SWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     misc_feature    29448..29461
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     misc_feature    29527..29540
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     misc_feature    complement(29528..29541)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            29532..31544
                     /locus_tag="DQN36_RS05695"
                     /old_locus_tag="NCTC13737_01127"
     CDS             29532..31544
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /locus_tag="DQN36_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01127"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="WP_111704239.1"
                     /transl_table=11
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGALD
                     NTRTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANSAL
                     LQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEAS
                     HQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQNYEH
                     YQFLDVAETIAKYAKELQEQHVHAIVVLAHVPATSKDGVVDHEMATVMEKVNQIYPEHS
                     IDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSANVVAVAP
                     GIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISRTENIDKESPVGNLVTTAQLT
                     IAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQMTGQHIYDV
                     LNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLTTTYTVVVND
                     FLYGGGDGFSAFKKAKLIGAINTDTEAFITYITNLEASGKTVNATIKGVKNYVTSNLES
                     STKVNSAGKHSIISKVFRNRDGNIVSSEVISDLLTSTENTNNSLGKKETTTNKNTISSS
                     TLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     misc_feature    complement(29543..29556)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.33"
                     /tool="antismash"
     gene            complement(31626..32036)
                     /locus_tag="DQN36_RS05700"
                     /old_locus_tag="NCTC13737_01128"
     CDS             complement(31626..32036)
                     /EC_number="3.5.1.88"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /locus_tag="DQN36_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01128"
                     /product="peptide deformylase"
                     /protein_id="WP_002984994.1"
                     /transl_table=11
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMA
                     ANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITVEY
                     LDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(32292..32510)
                     /locus_tag="DQN36_RS09200"
     CDS             complement(32292..32510)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995561.1"
                     /locus_tag="DQN36_RS09200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_111704240.1"
                     /transl_table=11
                     /translation="MALLFYYYVRKNQVKKLSQLKNLTEIFRKFIILTINNISAIKAFQ
                     TAGVLFGPVKTANARESSIWFENLTKQ"
     gene            complement(32928..34805)
                     /locus_tag="DQN36_RS05710"
                     /old_locus_tag="NCTC13737_01129"
     CDS             complement(32928..34805)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /locus_tag="DQN36_RS05710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01129"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_111704241.1"
                     /transl_table=11
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTTL
                     LDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDASSVLDTVLSSDVKAIQLIRQYE
                     LLMANYTEDKQESLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGMRRR
                     VQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHVATRI
                     FELDKAGLTEYQGNYQDYVRLKAEQDERDATNLHKKKQLYKQELAWMRTQPQARATKQQ
                     ARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQ
                     NKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMDETKRVIN
                     YLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLKLLIEKPNV
                     LLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFEEGDIRIFYG
                     NYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKKRMSYLEKQEWAQIEDKIATIE
                     ANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLDI"
     gene            complement(34802..36010)
                     /locus_tag="DQN36_RS05715"
                     /old_locus_tag="NCTC13737_01130"
     CDS             complement(34802..36010)
                     /EC_number="2.7.7.72"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /locus_tag="DQN36_RS05715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01130"
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="WP_002990193.1"
                     /transl_table=11
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIHD
                     VDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQVS
                     FVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLEQKRLRAVGKAEERFEEDALRI
                     MRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGISAMIA
                     CQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTS
                     NDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDHIEALDQ
                     ALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREE
                     LAT"
     gene            complement(36135..36983)
                     /locus_tag="DQN36_RS05720"
                     /old_locus_tag="NCTC13737_01131"
     CDS             complement(36135..36983)
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /locus_tag="DQN36_RS05720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01131"
                     /product="DegV family protein"
                     /protein_id="WP_002990194.1"
                     /transl_table=11
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLSI
                     DDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLA
                     EEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIMVDD
                     LNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLI
                     ADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPR
                     L"
     gene            complement(36983..37363)
                     /locus_tag="DQN36_RS05725"
                     /old_locus_tag="NCTC13737_01132"
     CDS             complement(36983..37363)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /locus_tag="DQN36_RS05725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01132"
                     /product="DUF1149 family protein"
                     /protein_id="WP_002985011.1"
                     /transl_table=11
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDEQ
                     QKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDMVK
                     RLTYEVTEIALDRPGIHLEFKN"
     gene            complement(37591..37767)
                     /locus_tag="DQN36_RS05730"
                     /old_locus_tag="NCTC13737_01133"
     CDS             complement(37591..37767)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQN36_RS05730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NCTC13737_01133"
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="WP_002990197.1"
                     /transl_table=11
                     /translation="MIKPYGFKYGLVGEVLRRIERLGFTFERLELRQASSKYLAKHDEA
                     LVINLFILDLKLT"
     gene            38266..39291
                     /locus_tag="DQN36_RS05735"
                     /old_locus_tag="NCTC13737_01134"
     CDS             38266..39291
                     /EC_number="3.4.22.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635407.1"
                     /locus_tag="DQN36_RS05735"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases.; This family includes IgM or IgG-cleaving
                     cysteine proteases.; This family includes IgM or
                     IgG-cleaving cysteine proteases; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="NCTC13737_01134"
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="WP_111704242.1"
                     /transl_table=11
                     /translation="MRKRYYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIIYSEVTP
                     YHVTSVWTKGVIPPANFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNMLH
                     WWLDQNNEKIEAYLNKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKAFPG
                     LSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGDQSKL
                     LTSRHVFKEKTLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSNGNLKV
                     IYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQDSWNQT
                     N"
     gene            39372..39677
                     /locus_tag="DQN36_RS09120"
                     /old_locus_tag="NCTC13737_01135"
     CDS             39372..39677
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014875.4"
                     /locus_tag="DQN36_RS09120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01135"
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="WP_269460108.1"
                     /transl_table=11
                     /translation="MGNSKKTLINPIKIDKDIVTIQEFDFKIRKFLMESKEIYLTKSPY
                     IRGSLEIHSKNRKHEKINLYDAKPNSTRSDVFKKYKDNKTINMKDFSHFDIYLWTK"
     gene            <39875..40192
                     /locus_tag="DQN36_RS05745"
                     /pseudo=""
     CDS             <39875..40192
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /locus_tag="DQN36_RS05745"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="KCYDGTI"
     gene            complement(40249..40956)
                     /locus_tag="DQN36_RS05750"
                     /old_locus_tag="NCTC13737_01136"
     CDS             complement(40249..40956)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /locus_tag="DQN36_RS05750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC13737_01136"
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="WP_002990206.1"
                     /transl_table=11
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSST
                     RHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNGSS
                     VTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQDATA
                     ALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAET
                     LAVDEAWAKRMTY"
ORIGIN
        1 agccaatcta cgccagtcat gccctctttt tctaaaatag cgttggttct tgaaaaaggt
       61 ttgctgccaa aaaagccacg ataagatgac aaagggcttg gatgagggct ctcgatgatg
      121 tggtgctttg gattagtaat gaaggctttt ttcttccttg cataagctcc ccacaaaatg
      181 aaaactacag ggctgtcttt ctcattcagc actttaataa cagcgtctgt aaatggctcc
      241 catattaagc ctgcatgccc attagcctgg cctgctggca ctgttaagca agcattcaaa
      301 agcagaaccc cttgactagc ccaagtgctt aaatcatgat ggtcacgagg accaatgtca
      361 tctgctaatt cttttaaaat attaataagg gatggcggag cagaaatctc ttctggaact
      421 gaaaatgata agccctgggc ctgtttgggg ccatgataag ggtcttgtcc taaaatcaac
      481 actttggttt cttccaaagg agtgacttgt aaggctttaa agacattttc tcgtggagga
      541 tagacaagac cggaagcata ggcttcatct aaaaagtgat tgatgcgacc gtagtaatgc
      601 tccggcaaaa atgatttgat tttctcatgc caaattgaat gagccataag attcctttct
      661 aatcacgtca gtttctaagt taaatacgat gtccttttct atctagttta ccacatttta
      721 aatagaaaga ccctgaaaat atgatatttc cagggttaat attcgttttt tacaggatat
      781 taaacaagtg ctagcttatt ttctaagaat tcttggtaac gttctaacaa aaaagcaata
      841 agccaataga taaaggctac taaaatatac atggacatgt aatcccactc tctaccgcca
      901 ataattttgg cattttgaaa aatatctggt acggtaatca tggcagctag cgacgaactt
      961 ttaaccatat caataatgac atttcctaaa ggaggaactg caattcgaaa agcttgagga
     1021 agaataattt tcttaaccat aagagcatat ggcaacccta aagccttagc tgcttcccac
     1081 tgtcccttgt caatagcttc tatagaagag cgaaaaactt cagaaatata ggcagcgcta
     1141 accatagaaa aaccaagata agcgcaaagt aaagctggca attctaaacc ataataaggc
     1201 aacccgaaat aaagaacaaa gagcacgacg atcatcggca cacctcgcat aatagagatg
     1261 tacgctctaa caagataatg aatcaacggc tgacatgacc ttcccagaag ggctaggcct
     1321 aaacctaaaa acagacccgt aaaaaaactg agcaacgaaa taccaagggt ataaggtaat
     1381 cccgataaca caaatcctaa actatctttc attaatggga tattaatcat gtctttagga
     1441 ctcctttaac atcaagtatt agttaacgtc tttcgtatca atgacgggaa ttttcttgtc
     1501 tttaccaaaa ggttttgtca aatcttgacc agcatagtag gtttcagaga ttttcttcaa
     1561 gctaccatct tttatcatgt ctttaataac agcatctatt tttttcttga ggctatcgtc
     1621 ttttttgttc ataacaattc cttgttcggt tgggttgtac tgaacatcgc tcattttgac
     1681 atttagattt ggattttgag ataacatgta atccacaaat aatttttgag ctgggtaatc
     1741 atttgggatg aaatctgttc gaccgttagc cacatcgttt agataaacat ctcctgtaac
     1801 attatcgtag gtcaccagtt cggctccctg tttttgcgct actttcatgt attctgttcc
     1861 agaagcacca gctgcttttt ttcctttcca gtcgctaaga tcttttttag ccatgtttga
     1921 gctgccatca gcacggacaa tcatgcctcc taccccgtat ttataaggcg tagagatatt
     1981 gtattttttc tgacgttttg gggtaatgtc aaagttgttc aaagaaatat ccactcgacc
     2041 actatcaact gaggtaaacg cttggtcaaa tcctgtttca acaaacttga ctttaatgtt
     2101 aagtcgttta ccgatttctt tgaccatatc tacttcgtaa cctactaact cattattatc
     2161 gttgtaaaaa gaagttggct gataggttcc tggggtagct acttttaaca cccctttttc
     2221 tttgatagtg tcccaacttg atttttgaga tttatgtggc gcacatgctg ccaataaaag
     2281 gctagcaagt ccgatagaca gtaaagtaac tgatttcttc atagtaactc ctttattaag
     2341 ataagaatag tataacattt tgattaagtt gtgttatcag tgagcgctca atctctttaa
     2401 aaagttaatc tataatagtt aaactgtttt ataagattat tattgaggaa tcttcaataa
     2461 tcctgctgcc tcaaactgtt ctgcaattcc taataatagg tcctctctac ctttggctgc
     2521 aattagttga atgcccattg ggagaccttc cttagtttcg taagtaggta aactaatagc
     2581 tggctggcca gttagattag gcagagctgt gtaaggatta atagccagac tcttaccaaa
     2641 catggtttcg accaaattga attgctcttc actgctgaaa atttcagctt gagccaagtt
     2701 agccatgagt ttcgaatctg ggacaagttc tccgtgctta ggagctggtg tgttggttgt
     2761 gaacgtcaac aacaggtcat aagtctcatg aaaactagcc atggttgcac tgtacgtatc
     2821 ccatttttga aggacctgtg agtaacgcca agctgggatg tctttacctg attggtaaat
     2881 agcccaggtc atggtttcca tatcgtcttt ggtcatcgga cgtccaaaag tgtcttcaat
     2941 atcagcaaac atagcagccg tttccacact attcataata taataatgac gaatcacttc
     3001 tgtcatattt acaggaaact cttccaattc aactagctga tgcccttgtt ctcttagcca
     3061 agttactgct tgtcttaaag cttttgcagt atctaaagat actgggctac cgtcacttaa
     3121 ccgttgataa aaagcaattg tcaagggacg ttgtagcgat tgataaatac tatcttttgt
     3181 taaggtggct agggggaagg ggctttccat ttgttccatc tgtaaatagt agagtagatt
     3241 tctagtatct ctaacggatt tggtcaaggc aaaatgaact gaggctcctt gccagcttcg
     3301 ataagaacca ggtccgacag gcatgcgccc acggctaggt ttgagcccaa ttaagccatt
     3361 aaacgaggct ggaattcgaa tagaaccacc accatcacta gcagttgcta gtgcactaat
     3421 tcctgatgac actagagcag cagctccccc agatgagcca ccagcatttc gtgtattatc
     3481 ctttggtaaa ttcactggtc cgtgcaaact gctatcgcta atatttttaa agccaaattc
     3541 aggcgtgttg gagcgcccta aaataataaa gcctaaagct tctaatcttt tcacgaataa
     3601 atctgtttta gtcgcatgat gattcttgaa tagcttagaa cccgatgttg ataagtctcc
     3661 cttcaattct tgtcccaaat ctttcaaaaa aatgggaact cctgcaaaag gcttacctga
     3721 aaaatccctt tgtttggcct cctctagagc tgcttcaaag cgttctgagg taatagcatt
     3781 taaggtaggg ttcaactttt tagccttata aatagcctgg gttactaatt ctagtggtgt
     3841 ggtctgaccg gtctgaacag caatagccat agccgtcgca tcttgataag tcatagctac
     3901 tcttcctttc taagatatga atcctaaaac attctttttt attaaaacac aaataaaaga
     3961 aaaccaccat taaaaggtta gaaattagaa tgtgatgtgt aaggaatgta gacaaaacaa
     4021 tcaaaacata acattttgaa ttggggttaa agagattttt tcattaaaaa taaacctggc
     4081 tgatagttcc ttattgttgc cagtttacct ggtcttcttt aaatttttta agtaaatgta
     4141 aaccatcatt agtaatatag ccttgcaact ttgcaactgc aattagctca gtataattag
     4201 aaagcgtaat caacttgata ccagcttctt taaaattctg actagctttt ggtaactcat
     4261 aagtgaaaat cgcaacaact cccagaacgt cagctccctc acgactggct gctgcggctg
     4321 catctagtac cgaaccacct gttgaaatca aatcttcaat gataaccatt ttttggcctt
     4381 taagcacacg cccctcaatc tggttgcctg ctccatgatc ttttggctta ctgcgaatat
     4441 aagcaaaagg aagagtcatt ttatctgcta taatggcacc gtgaggaata cctgctgtag
     4501 ctgtaccagc gatgacctca acttctggga aatgagccct gatagtttcc acaaacccat
     4561 tctcaattaa atcacgagtc ttaggataag aaagggtgac acgattatca gtgtaaatag
     4621 gtgatttaat gccagatgcc cacgtaaaag ggtcttcagg ctttaaataa acagctttaa
     4681 tatcaagtaa ttgagttgca atttggcttg ctagtgtcat ttcttattct cctttttctt
     4741 ctttaacaga caagtgttgg tttcctaatc ttatctgtta gcctgcccac tcagctttta
     4801 tggcttggta agcagccact gggtcctttg cctgggtaat tggtcgccct accacaatat
     4861 aatcacttcc aatacgtctt gcttggtttg gagtcatcac tcgtttttga tcgccaatat
     4921 tactgccttt aggacgaatg ccaggagtta agcaagtaaa tcccgtaggc gtcaccgcct
     4981 tgatagcttc tacttcttgt gccgaacaaa ccaccccatc tagctgagct ttagctgccc
     5041 ccttgctgta atgcaaaaca gactctaaaa gactcgtttg aatattttga tcaccacgca
     5101 tttggtcttc actggttgaa gttagctgcg ttaccgcaat taaggtaggg ccttgaccta
     5161 gtccttctcg agctgctttt agcatctcta caccaccagc tgcatgaaca gttgccatat
     5221 caatatctaa ttctttaaga actgccatag cagcacgaac agtatttgga atatcatgta
     5281 attttaaatc caaaaataca ttatgcccta acgatttgat ataccgaaca atatctggtc
     5341 cttgcgcata atataattcc ataccaattt tcacgtatag tttttcttct gctggaaata
     5401 agtctaaaaa tgctttagtc tcctcaaatg atgaaaagtc taaagcaata attgggcgtt
     5461 cttctttcat aacttatcct ttctataatg tgtcaatatc tcattaagca ccaaaaagcc
     5521 tcgctaccaa agaagcgagg ctacagcaaa ctaaaaggga attccctttt tttatcttgt
     5581 ataccttgtt tgcctctctg gactcactta aaggtgtcta aatttaaact attatagctt
     5641 ttttaaaaca agatgtcaaa actttttgtt atttgaacac atttttccta ctatatcttt
     5701 ttttgtatac ttacgtcaac tcattttatc atttttaccc aatcatttat tcaaactcac
     5761 ctgtgggtat cttagggctt tggtaatatt ttataaaagc ttcttcttca agattaaccc
     5821 tctggatatg ttcatagagc acatccggaa taggagcttc cttaagtgac aaagcactca
     5881 cttttaaaga tgaaaaaaca tcacttaaga ccccaaaaac tcgaatgcgt ttatctccaa
     5941 taataatttg aaagacttct ttggactggc ataaatctat cagatgatcc actcctttaa
     6001 tccaattatc gacaatatcc aaagttttgt tcatcaactt aaaagctgat tcttcatacc
     6061 aaaaggtaga ctcaatcaag cgttgctgca tatccaaggt atcaatggcc gcaacaatat
     6121 ctcccaactc agactgtact aaatgagctg gaaattcccc tccaagtata gaaggagttc
     6181 gttctacaag cttcagttca tctcgaaaaa gagtcaaata gtggatactg accaataact
     6241 tttggattaa gatttgatga ctattttgtt cagtaacatt cacacgacca ccaccctttg
     6301 attagaaaaa tacctatttg ttaatactat taatataaca caagaaaaat aaaagggcaa
     6361 tgaaattgat agattcaact ctcaaaattg aatcgtattt atcctaggcc atattgagaa
     6421 aagactccag cgctttttca aagttctaaa cccatgatga cgtttgtgct tgcgtcttta
     6481 ttttttttga gctagactgt acttatgaga attcaacaac tgcattatat tatcaaaatt
     6541 gttgagtgcg gctctatgaa tgaagctgct aagcaattat ttatcacaca accaagtcta
     6601 tccaatgcgg tcaaggattt ggaaatggag atgggcatta ccattttcaa ccgaaatcct
     6661 aaagggatca ccttgacaaa agatggggtg gaatttttat cttatgctcg ccaaattata
     6721 gagcaaacat cactgttaga agaccgctat aaaaaccaca atactggccg agagctcttt
     6781 agcgtttcat ctcaacatta tgccttcgta gtcaatgcat ttgtctcact cctcaagcgg
     6841 accgacatga ctcggtatga actctttttg cgcgagacaa gaacttggga aatcattgat
     6901 gatgtcaaaa actttcgatc tgaaattggt gttctcttta tcaacgacta taaccgagat
     6961 gtcttgacca aattatttga tgacaatcat ttgactgcct ctccattatt taaggcacag
     7021 cctcatattt ttgtcagcaa atcaaatcct ctagcaacta aaagcctatt aagcatggac
     7081 gacttgagcg attttcctta cctgagctat gaccaaggga ttcacaactc cttttatttt
     7141 tcagaagaga tgatgtccca gatgccccac aacaaatcaa ttgtggtcag tgaccgtgcc
     7201 accctcttta acttaatgat tggtttagat ggctacaccg ttgccagtgg tattctaaat
     7261 agcaatctaa atggtgacca gattgtggct atcccgctag atgtccctga cgaaattgac
     7321 attgttttta tcaagcatga aaaagccaac ttgtccaaaa tgggggaacg ttttatcgaa
     7381 taccttctcg aagaagtaac ctttgattaa tgtctttttc aatcgtcata ctaaaaaaac
     7441 acggtagtaa gacctgtatc ggtcaagtta tcgtgttttt tgataaatat cagacaatag
     7501 attgtctcca aaggctcaac tcctttttaa taatggcatt catgtcatca aagtaaaaag
     7561 gctcacgtcg gtagattaca ccagaaaaag tcgccaaggt gataatgttt tccaaaaaag
     7621 cctgagaaga aaaatgagtg gtgcgatgca gttcctcttc atcaaaaggc ttaatcaaat
     7681 gagccagagg attacggaca gccttttcaa aatgtcgtaa caaaaaaacc aagtccttga
     7741 tttcctgagg taaggaggtc aacgtcaaca tgtctgctaa gcttttggtc gtcacattgc
     7801 gagactgctt ttgagacagg taagccttaa aaacctcgtg atcagattcc aacatggcct
     7861 gaaaatgcca ggtatcatat tggtcattct ttgtatcaaa aatataagtc ttgaagtttg
     7921 gaatttctga cgtgattagt ctgagaaaaa gtcggtaaag aataggcgac actgacctga
     7981 cgaaatcaat aatagcaccg ttttttactt taacttctaa atccaaaatg taattggcaa
     8041 tctgctcatc ttcaagcgat tggttaagcc ataatgaaca gtggtactgg tcttcaatgg
     8101 tccgattctc tgctgcatgt tccgccagaa aggcaaggtt caattctctg cgctctttta
     8161 acatctctag taaatagagg gcagttttag ggatatttgg caaggcttta gcaattctaa
     8221 aggcgtgatt ataagcatag acatccaaaa ggatgtctag tgtttgatta ttagtcattg
     8281 gcaattaagg tttccaagcc gaccttcatc atatcagtga aagtggtttg gcgctcttca
     8341 gctgtagtat cttcggttgg atcattcaag ttatctgaga tcgtcatgat tccaagggct
     8401 ttgacatggt gctgagcagc taaatagtaa agagctgctg cttccatttc gatggcttta
     8461 acacccaatt taccaagagc catattacgc tcaggcatgt tagtgtaaaa gacatcagaa
     8521 gaaagcacat tcccaacgtg agttgttact cccatttctc tggcgatatg gtaagccttg
     8581 tcaagtaaac caaaatcagc aatttgtggg aaatcaaatt ctggaaagtc attacggata
     8641 atatttgagt tggttgctgc tgcttgggca agcaccaatt cacgcacatg aacttctggg
     8701 tcaatcgcac ccgcagtacc aacacggatc aatgttttga caccgtaatc aacgattaat
     8761 tcacgagcat agatagagat cgaaggcatc cccataccag ttcccatgac agaaacgcgg
     8821 tgccctttgt aagttcctgt gtagccaaac atgttacgca cttcgttaaa acacactgca
     8881 tcttctagga aattttcagc gataaatttc gcgcgcaaag ggtctccagg tagaagaatt
     8941 ttatcagcaa tatcaccttt tttggcagaa atatggatag acattattaa gatattaaag
     9001 gcgacaaaga acaaagtaaa aataggaaac tgacgacgca tcccagatgc tagacagttt
     9061 atctttttta cacagttctc cgcccgtatt caattcaatg aatacagtta gccctacctt
     9121 tccttttatt ttgtagaagg tcagagggcg gacagaaagc aactgaaatt tagggaacta
     9181 acgccatgtg tgagcacaaa agttagttta tctagtttcc gagctttccg cccgtattca
     9241 attgaataca accccattcc tttcataatt gatattgaat agaagaagag agctaaaaat
     9301 cgagttcaaa taataaagga ctaactctct ttcctttatt atttaaaaat taatacgaag
     9361 aaatgttcga gtccatgctt aatttaaacc gaatacgtct ctttcccttc gttggttatg
     9421 ttagttagaa aagctagaat ctgagttcaa cattcataga actcacaccc cgtgattatt
     9481 ttttgatttt tttattgcga acagatgtgc caaactgacg acataaaata acattcctgt
     9541 aataatgctc cagttgattt tgttcgtcct acaactcagc taaaatagct ttaacaagac
     9601 ctttgaaatc ttctttaata tgttcagtca cttcaacaac ttcttcgtgg ttcaattctg
     9661 attggaaacc agctgcaaag ttagtgatgg ctgaaatgcc aagtacttta agtccagaat
     9721 gagcagccac aataacttct ggcacagttg acatgccgac agcatctgct cctaatactt
     9781 tgaaagcacg gatttctgct ggtgtctcat aagttggacc agttaagccc atataaacac
     9841 catcttctag tttgatgttc attttttcag ccacttcatg tgccttattg cgataaacct
     9901 tagtataggc atcagacata tcagggaagc gtggaccaaa ctcgtccaag ttttcaccga
     9961 ttagtgggtt atttccggtc atattgatat ggtctgtgat tgccatcaag gtacctgggc
    10021 cgtagccgat accaccagct gcatttgtga caagaacgcc ttcacatccc agagctttca
    10081 tgacacgaac agggaaagtc accacttcaa gcgggtttcc ttcgtaaaaa tggaaacgac
    10141 cttgtagggc aagtacttta cgaccagcta aatcaccgta gactaatttt ccagcatggc
    10201 caacaactgt tgatttgccc cagtttggaa tatctgcata atcaataaca acaggattct
    10261 ctacttcttc agcaagttca ccaagtcctg aacccagaat taatccaaat tctggagctt
    10321 caattccttt agcaactaaa aagtcttttg tttcgttaat tttagtcatc aatgacatct
    10381 ttttctcctt ttgcctcaat agggttcaca atctcgccat cctctttaat ataaggacta
    10441 ggcaggggaa caggaagaat atccagtaag gtctcagaag gacggcaaag ttttactcct
    10501 ttgcgagtca caacaatagg acgattgatc aaaattggat ccgtcaacat ggcattaata
    10561 acgtctttct cagctactgc ttgatttgct aatccatgag cctcaaattc aggaacattg
    10621 gttcgcaaga gttctcgcgc agagattccc atcgattgta agagctcaat taaagtctcc
    10681 cgattaggtg gcgtctgcaa atactcaata atagtaggct caatacctgc atggcgaatc
    10741 atggcaagaa cattacgtga agtgccacag tttggattat gataaatcgt gatttcttcc
    10801 attatcaatt actaactttc ttattttaag tgaccaagga atgactcccc aatcatggct
    10861 gtatcaactc caaaattttc tgcaacagtc gctgaaatat ctgcaaaatg cccttgtgga
    10921 ataagaccat ttccagtaaa ggatgcagag taggcaagca atggaatgta ttcacgagtg
    10981 tggtcggtgc ctgcataggt tgggtcatta ccatggtcag cagtgatgag aagcaaatcg
    11041 tcttctttca tatttgcgat gatttcaggt aggcgattgt caaattcatg caagcagtcg
    11101 cgataaccct ctgggtcacg acgatgacca aagttggcat caaaatcaac gaggttagta
    11161 aaggagaatc ccttagtaaa ctcaggtaat tgaagagtct taataagcgt gtcaatacca
    11221 tggctgttcg acttattgtg tcccatgtcg tttgtaatac ctgaaccatt aaagatgtca
    11281 ttaatcttac caacggcata agttgggaca cctgcgtcag ccagtttgtt caaaacggta
    11341 tcttggaaag gagacactgc atagtcatga cggttagccg tacgtgtaaa gtttcctggt
    11401 tcgcctacat aaggacgcgc aataatacgg cctaaaaggg cagggcgttc aagcgtgatg
    11461 gagcgagcat attcacaaat cttgtaaagc tcttccacag gaataatgtc ttcatgggct
    11521 gcaatttgaa gcactgggtc tgctgaggtg taaacaatca actcacctgt ttccatttga
    11581 cgcggaccaa aatcatcaat aaccgcagtt cctgaatagg gtttattagc ttcacgaata
    11641 attttgcgac ctgagaattc ttcaatctta gttaaaatct cttctgggaa accattccag
    11701 aaagtgtcaa aaggttctgt aatgttcaag cccataattt cccaatggcc tgtcatggta
    11761 tcttttccaa gagatacttc ttccaatttg gtcacgtaac cagtaggatt atcttctgtt
    11821 ggaacagttt ttagtggtat tggacgagaa atgtttccaa gtccaatttt tgccatattt
    11881 ggaaccgata agcctgctgt ttctgaaata tgaccgaggg tgtcagaatc tgtatcagct
    11941 acaccagcat taaagaattt gtcagcatct ggtgctgcac caataccgac agagtctaaa
    12001 acaaccaagt gaatacgatt aaattttgac ataagtctcc aatctagggg aggttacggt
    12061 tgactcccca atacctataa aatacattaa cactgttata tgctaagact agcttgcttt
    12121 aggcgcttct aaaacagtaa cgccgtcttt actagcaaca atcaccttat caaccatacc
    12181 attaaagaga ccgtgttcca caacaccaac tgttccatct aacaggtgac caaaagcaac
    12241 aggatcttta atacaaccca aatcaagatc aataatatag ttttgcatgt ctgtcaccaa
    12301 acgactatca cctttcatac gaaaagacgg tttgtaacca gctttttcaa agacacggaa
    12361 caaacgatca gcaccatatt gaacgacttc gactggtaac ttaaaggcac ccagatgctc
    12421 taccatttta gaagcatcaa caacccagat gtattctttt gttggtgttg caacaatttt
    12481 ttccattagt aaggctgcgc cgccaccctt gattccattg aaatccttat ccacttcatc
    12541 agcaccatct acggtgaggt caatgctatc aatatcatct atcgatttta aaggaatgcc
    12601 taagacttct gcttgcttgc tagtcacact tgacgtagtc acaccaacca cttgcagtcc
    12661 ttcttgcttt acgcgacggc caatttcctc aacaaaatag taagccgttg acccagttcc
    12721 aagcccaatg gtcatgccat cagtcacata ttgcgcagcg gtaacaccgg caattttttt
    12781 gagtgcttcc atgattcccc cttataatag aattgcgtct tagcacttta ttataccatg
    12841 aaagcgccaa cttgttaatg aaaacatttg tttttctctc attgacagcc taagtgctat
    12901 agaataggat gatcttttta aaacttatga tttattctaa agtcatcata taagcactta
    12961 cttttcgtgt ttatttagct ttttgaaaat caagtgtttt cgtttgacct ttactgacct
    13021 tttgattata ataatactat aagatgagta aaaataatgt ctgaatcatt ttattagcaa
    13081 agggtttcct atcatgtgaa atcctaacaa cgattctgcg actgcttaca aacatcttat
    13141 agtctatttt ttattgcgag gtaactgata tgacacattt ttctggtaaa gatccttttg
    13201 taaatatgga tgatattttc aaccaattaa tggcaaacat gggtggttat cgtagcgaaa
    13261 atccccgcta tctcgttaac ggtcgcgaaa taactcccga agaattccaa cactatcgtc
    13321 aaacaggaca actccctgta gcgacaacca aagcaacaaa ttctcaaatg ttaacaccta
    13381 aagctgatag tgtattgact caactcggaa ctaacttaac acaagaagct cgtcaagggc
    13441 atcttgaccc cgtcattggt cgtaacaaag aaattcaaga taccgctgaa atcttggcac
    13501 gacgaactaa aaataatcct gtccttgtcg gagatgctgg tgtcggtaaa actgcagtca
    13561 ttgaaggttt agctcaagcc attgttaatg gagatgtccc agctgctatt aaaaacaagg
    13621 aaatcgtatc aattgatatt tctagtcttg aagctggtac acagtatcgt ggttcctttg
    13681 aagagaccat tcaaaacttg attcaagaag taaaagaagc tgggaatatc atcttatttt
    13741 ttgatgaaat tcatcaaata gttggtgctg gtgccacaag cagtgattca ggctcaaagg
    13801 gacttgcaga tattcttaaa ccagccttgt cacgaggaga attaacactg attggtgcta
    13861 ctactcaaga cgaataccgc aatactattt taaaaaatgc tgcactcgct cgtcgcttta
    13921 atgaagttaa agtgaatgca ccatcagctg aagatacttt tcacatttta atgggtattc
    13981 gtaatcttta tgaacaacac caccatatta cccttcctga taatgttcta aaagctgctg
    14041 ttgattattc tattcaatac atcccacagc gtagcctgcc agataaagca attgacttac
    14101 tggatatgac agctgctcat ttagctgcgc aacacccggt cactgactta aaaacactcg
    14161 aaactgaaat agctaaacaa aaagagaggc aagaaaaagc tgtcgccaaa gaagactttg
    14221 aaaaagcttt agcagcaaaa acacggattg aaacattaca aaagcaaatt gagcaacata
    14281 accaaagcca aaatgttact gctacagtca atgatatcgc agagtctgta gagcgcttaa
    14341 ctggtattcc cgtctctaac atggggacta atgatttaga aaggctcaaa ggaattagca
    14401 gccgcttaaa aagccatgtc atcggacaag atgaggctgt tgcagcagta gcacgtgcta
    14461 ttcgacgaaa tcgagcaggt tttgatgatg gtaaccgtcc aataggttct ttcctttttg
    14521 tgggtccaac tggtgttggt aaaacagagt tagctaaaca attagcactt gatttatttg
    14581 gttccaaaga tgctattatt cgacttgata tgtccgaata taacgatcgc actgctgtgt
    14641 caaaattgat tgggacaacg gctggttatg ttggctacga tgataataat aataccctaa
    14701 ctgagcgtgt tcgtcgtaac ccttatgcta ttgtcttact agatgaaatt gaaaaagctg
    14761 atcctcaaat cattacactt cttctacaag tgttagatga tggacgattg acagatggac
    14821 aaggaaatac tattaacttt aaaaataccg ttattattgc tacatcaaat gccggttttg
    14881 gccaacaaga tacggaaact tctgggtcta acattatgga tcgcattgca ccttatttca
    14941 gaccagagtt tttgaaccgt tttaatagta tcattaaatt taatcatctg caaaaagaaa
    15001 atttagaaga aattgttgat ttaatgctag ctgaagtaaa tcaaaccacc gcaaaaaaag
    15061 gtattagttt aacgattgct gatgacgcta aagctcattt gatagattta gggtacaatt
    15121 acgctatggg agctcgtcca ttacgacgta ttatcgaaca ggaaattcgt gaccgtataa
    15181 ctgattatta tcttgaccat ccagaagtca aaaaacttca ggcaattcta aaagaaggac
    15241 aactagtgat taggcaaaaa gatcagtaat aaacttcttc aattgaataa ttttcaaaat
    15301 atgaaaaaat ccgtcttgtg actacgttat acacttgacg gacttttttt tagcgctttt
    15361 ttaaaaataa ttttttcatc gcctaataac tcaagtttct ttccaaatct ggtgtaatca
    15421 aaataaccat taggtgtgag caatcctttt gaaaaagaag tatgtcccgc tgctacttct
    15481 tctttgatat caatggtgtg caaaatacga ttaacttttc ctttgagaac aacagcagat
    15541 aaatgtcctg ttttttgatt atatttgcct ccgatctgag aagctaattt ctcaaaagct
    15601 tgatctaaaa tcatttctaa ttcatggcta gctggcatac tattctcaat aatttggcgt
    15661 tctttactac tcaagtcacc aacaactaaa tgattttcct ttaatgtctt taataattca
    15721 ttttggtgat aagcagctaa acgtttgaca aaaatgtctc gttcaacttg aacactaaaa
    15781 ctcaagtcaa cgttgttatt tttaactgtt agtatcatct gagatgacgt taataaacta
    15841 tcatcaataa gagggctctg atgcaaacca gtaagacgtt tagcaaaatc atcgcctaac
    15901 ttctgatcaa tgcttgttgt tcgccagata ccttcaatag agctattacg atatcgaaca
    15961 ccaaaaagta cagcaagcaa gataagaaaa ataataaata caaaaagggc attgcattga
    16021 tggcataaca atgactttcc tttagagcgc ccttgggcta cttgtgtcat gactcatctc
    16081 cttaatataa aatactagca tgtcatcatt aaggcgtcaa gtaaaatcgg taaacctaac
    16141 tatgattttt tatgttttcg ataagaaaaa caccctctac tgagaatgtt ttagcataga
    16201 taaatcaaca cctatcgcta gacctgctct aaaatagcat cccaagaatc atcgatacca
    16261 atacgttcta ccgaagaaaa tactataaaa gtatcagatt tgtcaaaatt caaagctttc
    16321 ttgaccacag actcatgttt gttccatttg ccacgaggaa tcttatctgc tttggttgcc
    16381 acaacaataa caggaatgtc atagtacttc aaaaagtcat acatctgaat atcttctttt
    16441 gaaggggcat gacgtaaatc aaccaaactc acgactgcac gcagattgtc tctgctggtt
    16501 aagtattctt cgatcatctt tccccatttg gcccgttcac ttttagaaac cttggcatag
    16561 ccataaccag ggacatccac aaatctaagc ttgttatcaa tattgaaaaa atttaatagt
    16621 tgggtttttc ctggcttgct tgaggttctt gccaaatttt tgcgccccaa tatggtatta
    16681 ataaaacttg atttaccaac atttgaacgt ccagcaaggg caatttctgg caaatcatct
    16741 tgggggtaat gagatttatt ggcagcactc aataaaattg aggcgttatg ggtatttaag
    16801 acttgttctt cagccattat ttctccttaa gctgtctcta aaacgggttt tgacttgcct
    16861 tcgacagcag ccttggtgat acgcactttt gtgacatctt cttggcttgg aatttcaaac
    16921 ataatgtcta acatcgtttc ttcaataata gaacgaagac cacgtgctcc tgtcttacgt
    16981 tcaatggctt tattggcaat ggcttctaag gcttccttat caaatgccaa ttcgacgcca
    17041 tcgtaagaaa gaagggcctg atattgcttg accagggcat tccttggctc tgttaagatt
    17101 cgaatcaaat ctgatatttt aagttgttca agggctgcca caactggtaa gcggccaata
    17161 aattctggaa taagcccaaa cttttgaata tcttctgaaa taatttcttg catataagaa
    17221 gcattgtcat caattttacg gctgttttga ccaaaaccaa taactttttc acctaaacgt
    17281 tgtttaacaa tctcctcgat gccatcaaaa gccccgccaa caataaacaa gatatttttt
    17341 gtatcaattt ggatcatttc ttgattaggg tgcttccgcc caccttgtgg gggaacactt
    17401 gctaccgtac cttcaataat tttaagaagg gcttgctgta caccttcacc agatacatca
    17461 cgtgtgatag atacgttctc acctttttta gcaatcttat ctatttcatc aacataaata
    17521 ataccacgct ctgctcgttc gacattatag tcagcagcct gaatcagttt gagtaaaata
    17581 ttttccacat cttctccaac ataccctgct tcagtcaaag aagttgcatc tgcaatagca
    17641 aatggtacat tgaggctttt agccagagtt tgtgctaaga aggtttttcc tgaacctgtt
    17701 ggtccaatca tcaaaatgtt ggacttttgt aaatccacat catcgtcatc acgactttct
    17761 gtaaacgaga cacgcttata atgattgtac acagcaactg ataaagcacg tttagcacga
    17821 tcttgaccaa ccacatattg atttaaaaca tcaaggagct cttttggttt tggaacttct
    17881 gtcaaatcgg caaggacttc ttcagccaat tcttctttta taatttcttg tgataaagct
    17941 acgcattcat tgcagatgaa aacattattt cctgcgataa tttttttaac gtcatcctgg
    18001 cttttaccac aaaatgaaca gtatacttta atatcgttag ttctacttcc tgccatttct
    18061 tataattctc ttactttctc ttatctttta ctgaatttta atattagtca atgtgttgta
    18121 ttggtttttg gtgattcttg cttgatagct aaatcttcac cagtgctgtc tttgcaagtc
    18181 acatctcaaa acaatgtacc atagaaggcg tgaatactat taaccagatt agtaaacgca
    18241 tttaataaga acagacttcc taagccataa cgattctttt taaaagctgg gatggcacaa
    18301 agaacacaaa tcacgcacaa aaaagccgta aatactccaa aaatactacg ttgcatcgct
    18361 tatcatctcc tcagactatt tgtgttttaa agcagtaacg gtaaaatcat aaggattttt
    18421 agcgtctcga gcatagaacg tttggctttc ttgcgtgaaa tgactaaaat ctagatttgg
    18481 tcggtaggta tctcctttaa aacgatgatg gataactgtt tttatgatac gatcgaaata
    18541 accattaaac gcttctaaaa ccttattccc accaatgata taaagtgttt tatcctgcgc
    18601 atggtaccac tccaagactt tttcaatact agtcattgtc aacacctcat ctacttgata
    18661 atctctattt cttgtcatga caagggtttg acgttgagga agtcttttgc aattcattcc
    18721 ttcaaaagtc acacggccca ttaagattgc ttgatgtagc gttgtctttt taaaatgttc
    18781 taactctttt ggtaaatacc atggtaactt acccgcaaca ccaataagcc ctgcttcatc
    18841 ctctgcccaa atagcaataa tttcctttgt cattaattat ttccttcatt ttaaactcta
    18901 tttattttac caaatttatg aacaaaatgc tcacaaaaaa tctaaataaa gtttaaatag
    18961 caaggtcaaa gtgcaactga ggcttcactg gatcataatt ttgtaattca aaatcatctg
    19021 gtttaatatc aaagaaatta gtcccatctg gaacatttaa aacaagctta ggctgactgg
    19081 caactggctg tcgttttagt aattcttgag cctgatcaaa ttggttgtca taaatatgta
    19141 aattgttaac aaaataaaag aacttaccta ttttccatcc aaaatgttta gcaatcatca
    19201 tctgcaaggc aacgtattgc atggcattga tgtgatgagc aactaatatg tcattagaac
    19261 gttgcgtcaa actagcatct aaataaagat cttcccctac acgtctaaca tcaaacatga
    19321 tttgaaaggc acatggcaac aacccttttg tctcctcaaa tgcttcatag tcccagagag
    19381 aaatgacatt acgacgattc caaggatttt ctgctaattg ctttagtatt tttgagatga
    19441 tatcatgttt tttgactaca gcaccataac gttgtccaat agtacgtgtc tggtcaactt
    19501 cccattcatt ccaataatga acattatatt tagcttctag cacatctaaa ctgttagact
    19561 gatcttgata tatccaaaat aattccttta tagcagattt aattggaatg ggtcgtaaag
    19621 ttgtgatggg aaactctcct ttagctaaat catattcagc aaacgcccca gtaatatact
    19681 tagaatgagc tgttcgacca tctttatatt taggacgtgc ttgctcactc aatgatcctt
    19741 cgtttataat tttttgaata ttagctttaa aaatctggtc agcttttgtc atctctaata
    19801 acctttctgt aagcatactt catactattc taactaattt taccaaaaaa taccagaata
    19861 aataaacatt cgaaaaactt catgtggtca tgaacatttt aactattaaa ggataaaaca
    19921 aataacttta tcagtctaat tttgcagtaa aatgtgatag aatgggtaag actataaaaa
    19981 taactaaaag aaggacaaat atgacaattg gaattgataa gattggtttt gcaaccagtc
    20041 aatatgtctt gaaattggaa gatttagcgc ttgcacgcca agtggatcca gcaaaattta
    20101 gtcaagggct actcattgag tcttttagtg tggcaccaat cactgaagac attattactt
    20161 tagctgcttc tgcagcagat caaattttaa ccgacgaaga tcgatctaag attgatatgg
    20221 ttattttggc aactgaatcg agtactgatc agtcaaaggc atcagctatc tatgtacatc
    20281 acttagttgg tatccagcct tttgcacgtt cctttgaagt aaaacaagcc tgctatagcg
    20341 caactgctgc tctagactat gctaaactgc atgtggcttc taagccagat tctcgtgtcc
    20401 ttgttattgc tagtgatatt gctagatacg gtgtaggatc tcctggcgaa tcaactcaag
    20461 gctctggtag tattgctctt ttggtaactg ctaaccctcg tattcttgct ctaaataaag
    20521 ataatgtggc tcaaactagg gatattatgg acttttggag gcctaactat agtttcacac
    20581 cttatgttga tggtatttac tctaccaagc aatatctcaa ttgcttagaa accacgtggc
    20641 aagcttatca gaaaagagaa aaccttcagt tatctgattt tgctgcagtt tgtttccata
    20701 ttccatttcc caagttagcc ctaaaaggtc taaataacat tatggataac acagtacctc
    20761 ctgaacacag ggaaaaacta atagaagcct ttcaagcttc tattacttat agcaaacaaa
    20821 ttggaaatat ttatactggc tcactttatc taggattgtt atctttactt gaaaatagta
    20881 aagtattaca atctggagat aaaattggtt tttttagcta tggttccggt gccgtaagtg
    20941 aattttattc cggtcagtta gttgctggat acgataaaat gttaatgact aatcgacaaa
    21001 ctttactgga tcaacgaaca cgtctttccg tttctaaata cgaagacctt ttctacgaac
    21061 aagtccaatt agatgataat ggtaatgcca attttgacat ttacttaact ggaaaatttg
    21121 ctctaacagc catcaaggag catcgaagga tctatcatac caatgacaaa aactaatctt
    21181 aactggagcg gtttttcaaa gaaaacattc gaagaacgcc tccgacttat cgaaaaattt
    21241 aaactactta atgctgaaaa cttaaatcaa ctcaaaacag acgttctttt gcctatccaa
    21301 acagctaatc aaatgactga aaatgtctta ggacgattgg ctttgccctt tagcatagct
    21361 cctgattttc ttgtcaacgg ttcaacttat cagatgcctt ttgtcacgga agaaccttct
    21421 gttgttgctg cagcatcttt cgcagcaaaa ctaatcaaac gctcaggtgg ttttaaagct
    21481 caaaccctaa accgacaaat gattggtcaa attgttcttt acgatatcga ccaaatagat
    21541 aacgctaaag ccgccatcct tcataaaaca aaaaagctaa ttgcattggc aaataaagct
    21601 tatccttcca ttgttaaaag aggtggaggc gctagaacca ttcatttgga agaaaaagga
    21661 gagtttttga ttttctatct gactgttgat acccaagaag ctatgggagc aaatatggtc
    21721 aatactatga tggaagctct tgttcctgat ttaacaagac tgtctaaggg gcattgtcta
    21781 atggcgattt tatctaatta cgcaacagag tcgcttgtta ctactagttg tgagattccc
    21841 gtgcgccttt tagatcacga taaaacaaaa tccctacagt tagctcaaaa aatagagcta
    21901 gccagccgac tagctcaagt agatccttac cgggctacta ctcataataa aggtattttt
    21961 aatggcattg atgcagtggt aatagccaca ggaaatgact ggcgtgctat tgaagcaggg
    22021 gcccatgctt atgcctcaag aaatggtagc tatcaaggac ttagtcagtg gcattttgac
    22081 caagataaac aagttctgct tggccaaatg accctcccta tgcctattgc tagtaagggg
    22141 ggatctatcg ggcttaaccc tactgtttct atcgcacatg atcttcttaa tcaacctgat
    22201 gccaaaacat tagcccaatt gattgcatct gtggggttag ctcaaaactt tgctgcacta
    22261 aaagctctga cctcatctgg catccaagct ggtcacatga aactacatgc gaaatcatta
    22321 gctcttttgg cgggggcaac ccaagacgaa attgctcctt tagttaatgc tttactagct
    22381 gataaaccaa taaatctaga aaaagcacat ttttacttat cccagctaag acagtcttag
    22441 atttaaacaa ctaatataag gcaaacaccc atgtaaacaa ttggtttaca tgggtgttta
    22501 atctttgttt ctatacatac aagtcttaga aatagtctcc ataacatact ctatttactc
    22561 atctactcta ttctgagttt gatgaggtat ttataaatat tttatattat gttctaaaaa
    22621 agctctatca tctttgtagt aggtggcact attgtagagg tgatgaagcc taattgacct
    22681 gctgcaagcg tccatatagt aagtagtcga ctccctttaa ttctttaata gttttacagt
    22741 caagagcaca cataatgatt tttaattctt ctttccagcc gttaacgata gcaatcacac
    22801 gctcggttgg gtatttttcg accaattcta aaacggtgcg tgagagtccc actgcacgtg
    22861 ctcctaggac gaaacattta atcatgtcca aggggtgtct gacaccaccc gaagctaaga
    22921 tttccacttg gtccatcagt ccttgtgcat ttagcaagca ctgaacggtg gtttgtcccc
    22981 aatcgtttaa gtaagagcgg tctcctcctc tttgattttc aatataggca aatgaggtcc
    23041 ctcctcttcc tgaaatatca aaggtttgaa tgcctaggtc atgtgctagc ttgatactat
    23101 tgacatccat gccaaaacca acttctttga gaatgacagg aactggtatt tgactagcgt
    23161 attcagcgag gtgttttttc caggtatgaa agacgcgctc accctctggc atcagcaact
    23221 cttgcatcac attcacatga acctgtaaaa agaggggctg catttcttga accgtttgtt
    23281 gtcctagcgc cacaggttta tctagaccaa tattcgtggc tagtttcaag ttatctgcca
    23341 cctcatgtaa acgataggaa tcgtcgttag gattttttaa agcagcgcta taagaccctg
    23401 tcaccatgac aatccctgtt gctgctgcta ctttggccaa tttttcattg acagctttgc
    23461 ctttttgact tcctcctgtc atggcattga tgtaaaaggg aaagtcgaag tcttgcccgg
    23521 caaaatgagt actgagatca atatcagaca aatcatagct aggtaaggaa tgatgtatga
    23581 gttctatgtc atcaaaagca ttataaggcg attggtactt gagggcatat ttgatgtgat
    23641 catctttacg gttggtcatt ctctccccac ctttcttgat aaagtaatgc gatatcagct
    23701 tcttgccatt tggaaataag ggtatctctg gcattctgat taaaggcaag cgcgatgcca
    23761 caatctccac caccagaacc tgaagattta gcaacagcat cttgcttctg acaagcagct
    23821 accaaggtta ctagcttagg atggtagata gctgaatgaa gctcttttag gagatgactt
    23881 gctcctgcta aacttttctt gagttcttcc ttatgacctt cttgcaaagc taccatagct
    23941 gattgcgtta gctggtaact tgttcttaag aaagctgggg taatgctcgc tgtcacttgt
    24001 tgaatcatct gccttgaaat agcaggtatt ttagtccagc caaccaaaaa gtcacaaggc
    24061 agggctggtt gaatgacttg gatatggtaa ccccaatctt tgacgagaag tttttttaag
    24121 ggcatggtct gcagccaatt actgacctgt tctcggtcaa aggaggtata ggcgactaaa
    24181 gtctggtaag cgatacaggc aatatccccc atagacccat tatctccttg cttaagcaag
    24241 gtataagccg ctagtttaaa gagtaactct ggggttaaag taatctgata ataggccgat
    24301 aaggccttta aggttaagag ggtgacgcta ccacttgaac caatgccaaa ttttttgcca
    24361 tcgcgctcca tttttcccgt tataattagg gaaaatggct ccagttggtc aattgactgt
    24421 cctagataat cagcaaaggt tttaaccgtt gcttgaatca gtgcataaga ggcatcgggt
    24481 gtcatgcccg ctttatggga aaacatatct gaagctaatt gaatatgggc tgctgggcta
    24541 atttctgctg tcatcatcag tggaataaag tgaattaagg ctttttgtcc tggtgttaag
    24601 atagcatatt cgcctgtgag gtatagtttc ccacctgttt gcacacaata attagacatc
    24661 tggtaaatcc tttgtttttg aaacgataat acggtagttc ttgccaagtc gttctgctag
    24721 ttgagccaag tctttttcta aacataggac cttcacattt ggacctgcgt ccatggtaaa
    24781 ataacaagca aaaccttctt gacgcagttc tttcacagcc tccatagcct ggtaagactc
    24841 ttttgttagg taagaaaaag gaggattggc tgtctttgtc gtggcatgca tggccaaggc
    24901 attagcttct gttaactgac caactttctc aaaattatta gttttgagat aggtaagcat
    24961 atgttggtaa tcgattgccg attgttctac ccattgatca aatgtagttg aggtatcgcg
    25021 gcataacttc atgccctctc ggctagaaat tggctttttc gcagcattta agaccagcat
    25081 aatcatggcc attttcaagt cagtctcaac cttgtaaata gcaccactat ctttgtccca
    25141 agcagcgact gggccaaaaa aagaacgaga agatgatcct gaggcgaact tagccttttg
    25201 agctaaagct ttctgatcta gctgggtgtc aaataattgg tcacaggctt taaccaaggc
    25261 tgataagcca ctggaacttg atgataaacc tgcagctgtt ggcatattat tttgagtttc
    25321 catctttaca aaagcctgac caggttggcg aaattggtca atgatagcag aaattttggt
    25381 atgttcttcg tcattttgca agacaccgtt aatgtaaaac tgatcactgg ttgcagtatc
    25441 tggtaagaag gaaacgctgg ttgtggtgaa catgttttcc aaagtcaaag aaatgctaga
    25501 ggtcgaagga atcatcttag cttgattctc ttttccccaa tatttgataa tagcaatgtt
    25561 agcataggat gttacggtta taacatttgg atccacgtgt ttacggctcc ttcttctttt
    25621 aatctgtgac tgattttttc ggccatgtct ttggtatctg ctagggcaat catacagcca
    25681 cccaagccac cgcctgtcat cttagcgcct aaagcacctg ctcttagggc agcctccaca
    25741 agttggtcag ctttactgat gctaacgcca atggccttta aagcagagtg cgcttgtgtc
    25801 atgagctgac cgatagccac cttatttttt tggttaatcg ctctttcaag ggcttgtgtc
    25861 aaagctccta gtttagccag atagggcaaa ttcgtttcct caaactgtgc taccttattg
    25921 acggcctcac gtgtatgacc gtgaatccct gtatctgcaa tgataagata accatttaag
    25981 gcgatttcga tagtttcaaa gccaatgttt cggataaact taatggcatg gtcactaagg
    26041 catgtcttgg catctaaacc actaggattg gtgtgggcaa taatttctgc cttgttgact
    26101 aaaatttcca acaaatcatc cgagaggggt tcttgacaat aagaaaaaac ggctctaata
    26161 gctgcaatag aaacggctgc cgaagacccc ataccacgct tttgtggcac ttgtgaaaca
    26221 atctcataag caattggttc ttgtagtcgc tgcaaataat ccaaggcagc ataaatggct
    26281 gttgatagag tatcataaaa atcaaagacc aatggcttat cagctggaaa aatatgacaa
    26341 accacctcaa tatctgttaa aggcaaagca atagctgggt agccatacac aacagcatgc
    26401 tcacctatca aaatgatctt actgtgtgcc ttaccatatc caatgttttc gttcattttt
    26461 tatcttttca ttactaattc ttctaaactt ttaccttact attttacact aaatgattag
    26521 aaaatgcgat gatatatctt tttaaaatca tttcttcact gaaattaaca ataaagacta
    26581 tctactcttt ttaggatcat aacaaaaatt ttcttatttc aaactacctt ctttaatcac
    26641 tcttctacta aattaaacgt taaaaaccag cctcatgggc tggttaagca tcgtttatta
    26701 cctttaccta gacattatta ctagctaaag gtactgaaaa atgtttaagt caaatcacca
    26761 ctgtaaaaac aatagcatcg tttttataat ttacagttat cgttccttta aataacttaa
    26821 ccatactttc tgccatagat aaaccaattc cataaccttt ttctttgcta ttatgggatt
    26881 cgtcttcgcg ataaaagcgt tcaaaaaagc ggctgtaatc aatggatttt ccttccaaat
    26941 aggtattaga aacttctaat ttcgctcgtt ttcgtcttct tccaatagtg gttaaagata
    27001 ccttgaccaa gcctttagga tcacaatatt tattggcatt atcaactaaa attgtcacaa
    27061 gttcaaacaa tgacttttcc tccgctttaa tcataatatt cggctgaatc gtcaaatcaa
    27121 aacgtttacc atctttcaaa accagactct taaaatcttc agctgcatct tgagcaatag
    27181 ctgaaaagtc taccatatgt aataccacat ctggctgttc ctccaaacga gccaaagtaa
    27241 tcatttgatt aatcaagcct gtcaatcgct tcacctgatc acttgtactc ttggtccatt
    27301 ctgattctcc agtcattaat tcgaccaatt cattattggc tgagataatg gctagtggtg
    27361 tttttaactc gtggcctgca ttagtaataa agcgacgctg cttctcataa ttttggacaa
    27421 aaggtttgat gaccataccg gaaaaaagac tcactaaaac aacaaaaaag ataaatcctc
    27481 caaaggccaa catcattgaa acagctaata aatctcctac actacgaaaa taaaaggtag
    27541 tatctaaaat aacaaccagt ttttcttcat ttggcagctg agtaatcaag tacgaataaa
    27601 cactatcttg gtgacggtaa ctgccttttt cttccccaga cttagcaaaa agtctagcaa
    27661 aatattgggc ttcttctcta tctaaagctg aaatattagc agtattagaa gaaagtagat
    27721 gtccattagc attaaaaatg acactataat accgaaactg gcttaggcta tcttcagaca
    27781 gtttcgttcc aagtcgttta gagctttccg tagtgtcagg taatttacct ttatttgagg
    27841 aaattaaatg taaaatacgg ttaatttctt gttgactttg gtaacagcgt gccgtgttaa
    27901 taataccaac aattgaactt aaaataataa aaatggcaat agaagcaatc atgataaaac
    27961 gaatacggat acgattaaac atgtcacctc ctatttttct aataaacaat agctagtatc
    28021 tttatcacct gcaataatga catttgcttg aatagctaat aatttttgac gaagataaga
    28081 aatataaacc caaacaatag aagtatcata atcttcttgg tctgaccaaa catgttggta
    28141 aagcgtttta gtatccaagt actttccttg atttaacatt aaaaaggcca ttaatttacc
    28201 ttctttagaa gctaatcgta tagcattacc ggcactcaat tcttgctcat taatatttaa
    28261 tgtgacacca gcaaattgta atacctgagg agtaaaactt tctactcgtc tttccatcga
    28321 ccttaatcta gctaaaagtt cttttaatga gaaaggttta gtcagataat catcagctcc
    28381 cgcatctagt ccggtaacac ggtcattaat ttctgccata gccgtcagca taataatatg
    28441 tgagcaattt cctgaagcgc gaatctcctt taaagcctca atgccagact taatcggcat
    28501 catgatatct aaaatcataa tatcatatgc attgtctttg gctttatcaa ttgcctcttg
    28561 accgttaaaa accacatcaa cgtcataacc ttgatgagtc atggcagttg tcaaaacatt
    28621 agacatctgc cattcgtctt cagctaacaa aattttcatg gttactcttc ctccgtcgtt
    28681 tcttgaatca attgacgaat ggtttgcatg gtaacatcac aagatgccaa ctcgtctgca
    28741 caacgcttta actctcttgt aatcatttct gcattagcaa cttgatgttt gtacttcatt
    28801 tgatgttcca agctagccca agagtcttga gcaatggttc gcaactgcac ttctataaaa
    28861 taacatcctt tttttttccc taaaatatct ggaaaatgtg tttctaattc caaaatgaga
    28921 tgatatgatc tatagccatt aggcttggca tttaaaatat aatctttttc agtgttaact
    28981 gacataccag gaatgctttt gagcaagtct accatccgat aaatatcatc aataaaacca
    29041 caaataatgc gaataccgat actatcttta atgattttta atgcagattt gcttgttaga
    29101 ggaagttgtt tgcgttgaca tttttcaatc atcgaagctt ccgatttaat acgggatgta
    29161 aagtgttcgt atagtttaaa ccctgtttct tttttgcttt tgatattctc agcaataatc
    29221 acatctgtta ttgtctgtag taccaacggc aagtacactt caaatccgct atatatagag
    29281 ctggtagaat aatgttctag tctttctttc atacgcttat tataacaaat tttctcaaca
    29341 aatgcttaaa tctctacaat gatcggttat ctttatttct aactatataa ctgtaaatga
    29401 tctttatcgt ttgtttttaa atcgctttca tgtatttttt gtacgttatt ttttaaaaat
    29461 accattgaat tacaaacaaa aacatagtaa acttgatcta taacgattac gttaacttat
    29521 taggagattt tatgaaaaaa tattttattt taaaaagtag tgtattgagt atcctgacta
    29581 gttttactct attagttaca gacgttcaag cagatcaagt tgatgtgcaa ttccttggcg
    29641 tcaatgattt tcacggcgct cttgataata ccagaacagc ttacacacca agtggtaaaa
    29701 taccaaatgc tgggacggct gctcaattag gtgcttatat ggatgacgct gagatagact
    29761 tcaagcaagc aaatcaagac ggaacaagta tacgtgttca agctggagat atggtcggag
    29821 ccagtcctgc taactctgca cttttacaag atgagcctac tgtaaaagtc tttaacaaaa
    29881 tgaaatttga atatggcact cttggtaatc atgaatttga cgaaggacta gatgaattta
    29941 accgtatcat gacaggtcaa gcgcctgatc ctgaatcaac aattaatgat atcaccaaac
    30001 aatatgagca cgaagcttcg catcaaacca tcgtcattgc taatgttatt gataaaaaaa
    30061 ccaatgatat cccctatggt tggaaacctt atgctataaa agacatagcc attaatgaca
    30121 aaatcgttaa gattggcttc attggtgttg tgactacaga gattccaaat ctcgttttaa
    30181 agcaaaacta tgaacactat caatttttag atgtagctga aaccattgcc aaatatgcta
    30241 aagaactaca agaacaacat gttcatgcta ttgtggtttt agctcatgtt cctgcaacaa
    30301 gtaaagatgg tgttgttgat catgaaatgg ctacggttat ggaaaaagtg aaccaaatct
    30361 atcccgaaca tagcattgat attatttttg caggacataa tcatcaatac actaatggaa
    30421 ctatcggtaa aacacgtatc gttcaagccc tctctcaagg aaaagcttat gcagatgtcc
    30481 gtggtacgct agatactgat accaatgatt ttattaaaac tccatcagca aatgttgttg
    30541 ctgtagcacc aggtatcaaa acagaaaatt cagatatcaa agctataata aatcatgcta
    30601 atgatattgt taaaacagtt actgaacgaa aaatcggaac tgcaactaat tcttcaacta
    30661 tttctagaac agaaaatatt gataaagaat ctcctgtcgg taacttagta acaacggctc
    30721 agcttactat tgctaagaaa acttttccaa ctgttgactt tgctatgacc aataatggtg
    30781 gtattcgaag tgacctagtt gtcaaaaatg accggaccat cacctgggga gctgcacagg
    30841 ctgtacaacc atttggtaat atccttcaag tcattcaaat gactggtcaa cacatttacg
    30901 atgtcctaaa tcagcaatac gatgaaaacc agacctattt tcttcaaatg tcaggtttaa
    30961 catacactta tacagataat gatcctaaga actctgatac ccccttcaag atagttaagg
    31021 tttataaaga caatggtgaa gaaattaact taacaactac ttacaccgtt gttgtcaacg
    31081 actttcttta tggtggtggt gatggctttt cagcatttaa aaaagctaaa ttaatcggag
    31141 ctattaacac agatactgaa gctttcatca catatatcac aaatttagaa gcatcaggta
    31201 aaactgttaa tgctactata aaaggggtta aaaattatgt aacttcaaac cttgaaagtt
    31261 cgacaaaagt taatagtgct ggtaaacaca gtatcattag taaggttttt agaaatcgtg
    31321 atggcaatat agtgtctagt gaagtcattt cagacctttt gacttctact gaaaacacta
    31381 ataacagcct tggcaaaaaa gaaacaacga caaacaaaaa tactatctct agttccactc
    31441 ttccaataac aggggacaat tataaaatgt ctcctattat gacaatcctt gccttgataa
    31501 gcttaggtgg actaaacgct tttattaaaa aaaggaaatc ctagcgttta ctagtaatcg
    31561 atcaccctta tataatcagg catctttgcc aaaaaaacct aaagcgtcct actctaggtt
    31621 ttttgttaaa ttaaaatacc ttctagatga tctaattcgt gctggcatat ttgagcagtt
    31681 aagcctgtta agcttaatcg ctttggtcgc caattatggt ccaaatactc aacagtaatc
    31741 ttatcatacc gctgtgtttt gcgatagcca gataacgaca aacaagattc tttagtttgg
    31801 taaattccct ttttagaaac catcacagga ttaaacataa ccaaatcaat aaatcccata
    31861 ctcacaataa caatgcgctt ttgttcacca atcatattgg cagccatccc aagacattcc
    31921 tgtctataaa aggctaaggt atcttgtaaa tcttggccaa tccatagatc ttctttcttg
    31981 gcgacttgcg ctttttgctg taataaaaaa tgatctgtta tgatttctct aatcattctt
    32041 atctccttaa accttctttt taattcataa actacatgtt caatggacta ttatcaccat
    32101 atgatagact tagtatcatc tgtttaaaac atcaggtgat tccttatttc aagatatctt
    32161 gggcaacttt atgaaattct gcaatatgag taccaaataa aaattgacct gcatcagcag
    32221 attgttgcta agttctcatc acaatattat cgaatttact gtctgctcct tcaaatgtct
    32281 aagagagata gttattgctt tgtgagattt tcaaaccaga tactgctttc tcttgcattt
    32341 gcagtcttaa caggtccaaa taaaacacct gctgtttgaa atgctttaat agctgatatg
    32401 ttgttaatag ttagtattat aaattttctg aatatttctg tcaagttttt cagttgactt
    32461 aactttttta cttgattttt cctcacgtaa taatagaaaa gaagcgccat aatgtaaact
    32521 acaccccaaa cgttagataa aaaaatctaa cgtttggggt gtttttgtat gacattaagc
    32581 tatgaagata agctagatat ttagcgctaa aaaaaccgag ggaactccgt ttgaaagaag
    32641 catctctgca aagaagaaga caaaaaacca ttataaagaa tggacaaaga cgagttctga
    32701 ttaaattttc ttttaagaac ggctaaattg actcgttcta cctactatta ttatcgatta
    32761 ttgcaacaat aaccgtatta aaataaaacg aaaaggactt agtcctctac aacacagaac
    32821 taaatccttt acttcaaata gagtagccaa cttttggggc tcagtgcaag agcccttctt
    32881 ttctattatc acttgtttat tataaacata acattaccat agtatactta tatgtctagt
    32941 ccactcaaat actcaaaccg ttcatacgcc aataataaat cattattgcg ctgatcgagt
    33001 tccttttgta attgagctaa ctggccataa tcactaacta cagttaacat ttggttttca
    33061 atttcttcaa tattagcctc aatagttgct attttatctt ctatctgagc ccattcttgt
    33121 ttttcaaggt aggacatgcg ctttttctcc tctttcggag gaagtggcac ttcttcagtg
    33181 actattgctt tagctaagtc agcctcaact gtttcttttt caaaagcttt ttcatcaagg
    33241 taatcactgt aattcccata aaaaatacga atatcgcctt cttcaaaagc taaaatctta
    33301 gtggctactt tgtctaggaa ataacgatcg tgactaaccg taatgactgg tcctgcaaag
    33361 ttagctaaaa agttttctaa gaccgtcaag gtggcaatgt ctaaatcatt tgttggctca
    33421 tcaaggagaa gaacatttgg cttttcaatg agcagtttta gcaagtagag ccgttttttc
    33481 tccccaccag ataatttagc aatcagcgtg ccatgacttg atctcggaaa aagaaattgc
    33541 tctaaaagct cactgatact cgttgttccc acgcttgttt taacctcatc agccacttct
    33601 tgaaggtaat taatgacccg tttggtctca tccatatctt tgagctgctg agagaaataa
    33661 cctacacgaa tagtatctcc aatatcaagc ttcccagaag ttggtttgag atcaccgttg
    33721 atgatattta acagggtaga ttttccgacg ccgttatctc caacaattcc aatacgatct
    33781 ttattttgaa taatcaagtt aaaatcctta atcaactgtc ggtcgccata agcaaaagaa
    33841 aggtcttcaa agtgaatcac cttcttccca attcggctcg tttcgaaagc catctccaat
    33901 ttatctgcag aactgtcttg gtgaacttct tttttcaagt cagtgaaacg attgattcta
    33961 gcctgctgtt tggttgcacg cgcctgtggc tgcgtcctca tccaagctaa ttcttgttta
    34021 tagagttgct tcttcttgtg taaattagta gcatctcgtt cgtcttgttc tgcttttaag
    34081 cgcacatagt cttggtaatt gccttgatat tctgtcagtc ccgctttatc caattcaaaa
    34141 atacgggtag ccacatgatc aaggaaataa cggtcatggg taataaaaag gacggttttt
    34201 ttagctgtct tgagataggt tgttaaccaa gcgatggtgt caatatcgag atggttggtc
    34261 ggctcatcca acaagagtaa gtcagcagct cctagcaata cttgagctaa ctggacacgt
    34321 cttctcatac cacctgatag gtctcccact ttttgttcca aatccgtgat gcctaatttt
    34381 gataggactg ttttgacatc actttcaata gaccaagcat ctaagcgatc catttcagac
    34441 atgagggact ctaagctttc ttgtttatcc tcagtataat tcgccatcaa tagttcatac
    34501 tgacgaatca gctgaatcgc cttaacatca gatgacaata ccgtatctaa aacagaggat
    34561 gcatcgttaa attcaggatc ttgtgttaag taagcgattt tgtaatcatt ggctttagaa
    34621 aatggtgaat ggtctccgtc aaaaccaagc cttcccgaca agacatctaa aagagttgtt
    34681 tttcctgttc cattaacccc aataatccca atacggtcaa agtcatgaat aataaaggaa
    34741 atatcctgaa agactgtttt atctcccacc gtttttgtca atttctccac caaaaaatgg
    34801 ctcatgttgc taattcctct ctaacaaatg cttcaattgt agtgaaatca ttatctaggc
    34861 gtccctctac aatcgctaat tcaactttct caagcataag ccctagctga ggacctggtt
    34921 tcatcccaaa atccttaatc aggtgagaac cattaaggac gatatcgtat ttgttatgaa
    34981 tggctagcgc ttgatctaaa gcttcaatgt ggtccatgtc aacagataag ctttgagctt
    35041 ttcggaggcc ttccactaga cttgccattt ccttgccgta ctggtaaata tccaattttt
    35101 caaaagatct ttcctgacga attctataaa gagcaatcaa ctttgtgaca taacgctgaa
    35161 aatcatttga agtcttccat gcttttagga agcttttagg atcctcaatg gctaaactaa
    35221 tcatcacata agcccaagct tggtggtgat cactaaaggt aaagttatct ttcaaagaaa
    35281 ctatcagatg attcaagcct gcttcctgct gcttcaagcc tggtaaatag tcataagcct
    35341 gacaagcaat catggcagaa atcccttttc gccagtgcgg tgccatcaat aatttatcaa
    35401 attcagtaaa agaacgttcc acagaaatct tttccaatag aggtgaatgg ctcctcatag
    35461 cttcaaaagt tgcagcttca atgtcaaaat ccagactcgc cgcaaatcga aagcctctca
    35521 taatgcgtag tgcatcttct tcaaaacgtt cctctgcttt acccactgct cgtaaccgtt
    35581 tttgctccaa atcaatgagt cctctaaatt tatcaataac ttgaccattt tcatccaagg
    35641 ccaaggcatt gacggtaaag tctcttcgtt ttaagtcttc ctctaaagag cgcacaaaag
    35701 aaacctgact aggacggcga tagtcaacat agacatcttc tgtcctaaag gttgtgattt
    35761 catactcacc gccattttca agcacgagca ctgtaccatg ttcaatgcca acatcgacag
    35821 ttctgttaaa aatcgcttta gtctcttcag gataggaact agttgcaata tctacatcat
    35881 gaatgggacg ctcgagtaaa acatctctga cgcttcctcc cacaaaatag gcttcataac
    35941 cagcttcttt tattttagtc aatatgggta aagccttctg aaactcagaa ggcattgtca
    36001 ttaatttcat acgttgtttt ctaacctatc atccaagtag cccaatctaa agtgtgatta
    36061 ggctacttgg gttctatcac attttgttat tgttttagtg attcttgcaa ttaactattt
    36121 tttctaatcg acaattaaag cctcggtgtt acgccaaatg caatggctcc ttctcctaaa
    36181 tgagtagcaa tcaccgctcc aaaatgaacc tcttcaatgt catattgata accactgtct
    36241 tgtaagagtc gtttcaaata atcagctttg tcttgtgctt ttgagtgaat aatagacaca
    36301 ttatactgac cgtctgctat caagtcattt aaaatctcaa ccaagcgttt catggctttc
    36361 ttttctgttc tcactttttc ataaacaacg atttttccct cttcatcaaa gcgtaaaata
    36421 ggtttaatac tcaaaagatt tccaagaaga gcagacccat ttgacaggcg tccgccttta
    36481 accagatgat taaggtcatc aaccataata aaggctgtcg tcccatcaat ctgttcttgc
    36541 agcttgttta aaatagcttg aaatgtcatt ccttgacgtg accaatctag cacatttttt
    36601 accatactac ctaaaggagc agatgtgatc ttactgtctg gaaatgccat ttcaatctca
    36661 ggatgttctt cagctaaaaa ttgaatattt tgccaaaagc ctgagattcc tccagctaag
    36721 aacaagccaa taacatgtgt ataaccctta gaagacaaaa gtcctaaaag attatctagt
    36781 tcagataaac ttggctgact tgtcttggga agattttggg agtcagccat cttttgataa
    36841 aaatcatcta tactcaaatt tcgaccttca aaataggtct catcgtcaat gataactggt
    36901 atatcaaggc taaaaatagc tttatcttgt ttcagatctg ttggtagtgt tgctgtactg
    36961 tcagtaatta ctgctaattt cattaatttt taaactccaa atgaatacct ggacgatcca
    37021 aggcaatttc tgtgacttca taagtcaatc gcttaaccat gtctagcaaa ggagcagcta
    37081 aggattcaac ttcctcttgc gtaaattcgc ttggtttatc cactaaacga tctaaaatac
    37141 gaaccatttg tgagatgacc ccactaataa caaattcttc tttgacaata acaaattgca
    37201 atacagatac aattactgtt tctttttgct gctcatcttt atcaatcaac tgaaaagtca
    37261 cttcaaaatt ggtctctggt gttccgtttt ctttttccca ctctaaattt ctagcatcat
    37321 aatggtactg gttgacaaat tctttttcac gaactaattg cattttttat tctccttggt
    37381 atcaatatga tccattatag catagatttg aaaattatta aagtagcccc taaactacta
    37441 tttttgcata acgttttaaa cagtgctatc tctcgaacag atatctattt tttcacctat
    37501 ttatatttag tcgtccttat actgacatta tatcaaaaaa acacccgtta gtgatcttgt
    37561 actgcacctc aattaaaaca gaaccactgg tcaggtaagt tttaagtcca ggataaaaag
    37621 gtttatcacc aaggcctcat catgcttagc caagtatttc gaactagctt gtcttagctc
    37681 tagtcgctca aacgtaaatc ctaggcgttc aatccgccgc aaaacctctc caactaaccc
    37741 atacttaaac ccatagggct taatcatcgc tccgcccttc ttcttttatc cattataaaa
    37801 taaaaacgtt ttaacagaca aaaaatagga aagtaccaga ctattggatt tattttttta
    37861 tctcaaactc cattaacgat gttgagttaa aggcattcaa aacaacatag atcgtaagct
    37921 aacaagattt tttatcaatt gaacctatcg tcctcagtta taccacgacc tcttctggat
    37981 gaggtctttt tttatttgtc taatttcatc aatgcttctt cccttctttc ttctatcaca
    38041 gctctcctat tgctcacttc ctcatgcagc aacatatcat caaaaaaccg ttcattttta
    38101 agcacaacca ctactgtatc tcttgtgatg tctccattgc aatcgcttgt ttaattttat
    38161 taaaaattat ttaaaaaatt aaatattatt ttaagaactt gcaataatat atgcctatat
    38221 tatataattt atttatcata aaattatata gaaaaaggta ttcttatgag aaaaagatac
    38281 tattcaactt cagctgcagt attggcagca gtgactttat ttgctctatc ggtagatcgt
    38341 ggtgttatag cagatagttt ttctgctaat caagagatta tatattcgga agtaacacct
    38401 tatcacgtta cttccgtttg gaccaaagga gttattcctc cagcaaactt cactcaaggc
    38461 gaagatgttt ttcacgctcc ttatgttgct aaccaaggat ggtatgatat taccaaaaca
    38521 ttcaatggaa aagacgacct tctttgcggg gctgccacag cagggaatat gcttcactgg
    38581 tggttagatc aaaacaacga aaaaattgaa gcatatctaa ataaacaccc agataaacaa
    38641 aaaatcatgt ttggtgatca agaattattg gatgtaagaa aagttattaa tactaaaggt
    38701 gaccaaacaa atagcgagct ttttaattat ttccgagata aagctttccc cggtttgtca
    38761 gcacgccgaa ttggagttat gcctgatctt gttttagata tgtttatcaa tggttattac
    38821 ttaaatgttt ataagacaca gactactgat gtcaatagaa cctatcaaga gaaagatcgc
    38881 cgaggtggta tttttgacgc cgtatttaca agaggtgatc aaagtaagct attgacaagt
    38941 cgtcatgttt ttaaagaaaa aactctcaaa gaaatcagtg atctcattaa gaaagagtta
    39001 accgaaggca aggctctagg cctctcacac acctacgcta acgtacgcat caaccatgtt
    39061 ataaacctgt ggggagctga ctttgattct aacgggaacc ttaaagttat ttatgtaaca
    39121 gactctgata gtaatgcatc tattggtatg aagaaatact ttgttggtgt taattccgct
    39181 ggaaaagtag ctatttctgc taaagaaata aaagaagata atattggtgc tcaagtacta
    39241 gggttattta cactttcaac agggcaagat agttggaatc agaccaatta aagcgtatca
    39301 ataagaaaga ttacattcaa cagatgatgg tattctaagg actaatacta ttgcagggaa
    39361 ttttttcata gatgggcaac agcaaaaaaa cattaataaa tcctataaaa atcgataagg
    39421 atattgttac gattcaagag ttcgatttta aaataagaaa atttttgatg gaatcaaaag
    39481 aaatttattt gactaagtct ccttatataa gggggagttt agaaattcac agtaaaaata
    39541 ggaaacatga aaaaatcaat ttatatgacg caaaacccaa tagcaccaga tctgatgtct
    39601 ttaaaaaata taaagacaat aagactataa acatgaaaga tttcagccat tttgatattt
    39661 atctttggac taaataagct aaaagctttg gataaatatg atcaattgac ctataataac
    39721 attgatacca aatctaaaac tgctcagatt gaattgcgcc ccaaaagtta gacaaaaaat
    39781 ctaataattg gggtgttttt gtctggcatt aagtttagct aataaccttg cttaaatcac
    39841 attaaaccaa taatggaaaa agacatctcc aaataaatgc tatgatggaa ctatatgata
    39901 gagtgatcaa ggttggcaat atcaacacaa ctattatcat catttcctaa actctaaagg
    39961 aattcgtccg tctgtgtcac gtaaaagaaa cagtcctgac aatagcatga tggaatcttt
    40021 ctttggcatc ttaaagtcag aaatgttcta tggttatgag aataactata aatcactaga
    40081 agacttagaa taagcgatta caaatgacat tgattattac aacgataaac atatcaaagt
    40141 aaaactaaaa ggatttagtt ctgtacaata cagaactaaa tcctttactt aaaatagagt
    40201 atccagcttt tttggggtca atgcaagcag attgttgtta gtgttacatt aataagtcat
    40261 gcgtttagcc caagcctcat caactgctag ggtctccgca tcagtgtaat tacgacgata
    40321 ctcattccaa acataacccg aagttgctag accagtttct tgagctgagc tattagcaac
    40381 atcataagcc gtcaaaccat aggttgcaat aatattattt agttttaagt tataactggt
    40441 gtctgtagcg tataagccag ttagagctgc tgtagcatct tgatacgata gcgtgtttga
    40501 ttttctagca cctatataag tgctagaact tagcaaatct gcatagtcat taagggagtc
    40561 tgcaatactt ggataagctc taaaggcttg atcaatcgta taggtattgc cattaccatc
    40621 atcttcccaa gttgacatcg tcacagaaga accgttatag gcacccttaa taccgaaaaa
    40681 attataataa ggtgcttgac ttagacttga tttaccatta cttgattcta aaatcgcttg
    40741 tgctatcata acagacgcat aaagatcacg ttcttgacca atagtactag cagttggacc
    40801 aatttcatca ataaaatgtc gggttgaaga actggcgata gtctcagctg acacgtttga
    40861 agttttatga gattgtctca ttgcactata agctcctaaa caagctgcta gaacaaaaag
    40921 actgataagt acaagcttac ctttcttttt tgtcattatt cacatatcct tttttataca
    40981 ttttctatgt ttctattata gcacacgaac gtttaaatta acttttccac agataattta
    41041 atgagattga taacttttgt cttgaaatcg acatatttct tctgattttt tttaaaattg
    41101 tggataacta tttcattaga ccatcaaaat tagtgagttg ataccattca atcaattcat
    41161 ttaatttggt atggta
//
