LOCUS       NZ_LS483337            41176 bp    DNA     circular CON 13-FEB-2024
DEFINITION  Streptococcus pyogenes strain NCTC12047 chromosome 1, complete
            sequence.
ACCESSION   NZ_LS483337
VERSION     NZ_LS483337.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1
  AUTHORS   Doyle,S.
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUN-2018) WTSI, Pathogen Informatics, Wellcome Trust
            Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 01:05:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,789
            CDSs (total)                      :: 1,700
            Genes (coding)                    :: 1,640
            CDSs (with protein)               :: 1,640
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 31 of 60
            Pseudo Genes (internal stop)      :: 23 of 60
            Pseudo Genes (multiple problems)  :: 19 of 60
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:22:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 698564
            Orig. end                         :: 739740
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LS483337.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41176
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="3"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41176
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41176
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21176](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21176)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            236..943
                     /locus_tag="DQL03_RS03640"
                     /old_locus_tag="NCTC12047_00724"
     CDS             236..943
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /locus_tag="DQL03_RS03640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00724"
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="WP_023611996.1"
                     /transl_table=11
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSST
                     RHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYHNFFGIKGAYNGSS
                     VTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQDATA
                     ALTGLYATDTSYNLKLNNIIATYGLTAYDVANSAAQETGLATSGYVWNEYRRNYTDAET
                     LAVDEAWAKRMTY"
     gene            complement(1000..>1317)
                     /locus_tag="DQL03_RS03645"
                     /pseudo=""
     CDS             complement(1000..>1317)
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /locus_tag="DQL03_RS03645"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="KCYDGTI"
     gene            complement(1900..2925)
                     /locus_tag="DQL03_RS03660"
                     /old_locus_tag="NCTC12047_00726"
     CDS             complement(1900..2925)
                     /EC_number="3.4.22.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /locus_tag="DQL03_RS03660"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases.; This family includes IgM or IgG-cleaving
                     cysteine proteases.; This family includes IgM or
                     IgG-cleaving cysteine proteases; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="NCTC12047_00726"
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="WP_032464307.1"
                     /transl_table=11
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIRYSEVTP
                     YHVTSVWTKGVTPPAKFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNMLH
                     WWFDQNKEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKAFPG
                     LSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGDQSKL
                     LTSRHDFKEKTLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSNGNLKA
                     IYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQDSWNQT
                     N"
     misc_feature    complement(2948..2961)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.62"
                     /tool="antismash"
     gene            2987..3181
                     /locus_tag="DQL03_RS03665"
     CDS             2987..3181
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /locus_tag="DQL03_RS03665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_032464308.1"
                     /transl_table=11
                     /translation="MQFFKIIFNKRKQAIDNGDITRDTVVVVLKNGRFFDDMLLHEEVS
                     NRRAVIEEREEEALMKLDK"
     misc_feature    2992..3005
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.36"
                     /tool="antismash"
     gene            3410..3586
                     /locus_tag="DQL03_RS03670"
                     /old_locus_tag="NCTC12047_00727"
     CDS             3410..3586
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQL03_RS03670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NCTC12047_00727"
                     /product="hypothetical protein"
                     /protein_id="WP_032464309.1"
                     /transl_table=11
                     /translation="MIKLYGFKYGLVGEVLRRIERLGFTFERLELRQASSKYLAKHDEA
                     LMINLFILDLKLT"
     gene            3814..4194
                     /locus_tag="DQL03_RS03675"
                     /old_locus_tag="NCTC12047_00728"
     CDS             3814..4194
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /locus_tag="DQL03_RS03675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00728"
                     /product="DUF1149 family protein"
                     /protein_id="WP_002985011.1"
                     /transl_table=11
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDEQ
                     QKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDMVK
                     RLTYEVTEIALDRPGIHLEFKN"
     gene            4194..5042
                     /locus_tag="DQL03_RS03680"
                     /old_locus_tag="NCTC12047_00729"
     CDS             4194..5042
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /locus_tag="DQL03_RS03680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00729"
                     /product="DegV family protein"
                     /protein_id="WP_011054370.1"
                     /transl_table=11
                     /translation="MKLAVITDSTATLPIDLKQDKAIFSLDIPVIIDDETYFEGRNLSI
                     DDFYQKMADSKNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLA
                     EEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIMVDD
                     LNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLI
                     ADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPR
                     L"
     gene            5167..6375
                     /locus_tag="DQL03_RS03685"
                     /old_locus_tag="NCTC12047_00730"
     CDS             5167..6375
                     /EC_number="2.7.7.72"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /locus_tag="DQL03_RS03685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00730"
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="WP_032464310.1"
                     /transl_table=11
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIHD
                     VDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQVS
                     FVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLKQKRLRAVGKAEERFEEDALRI
                     MRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGISAMIA
                     CQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTS
                     NDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDHIEALDQ
                     ALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREE
                     LAT"
     gene            6372..8249
                     /locus_tag="DQL03_RS03690"
                     /old_locus_tag="NCTC12047_00731"
     CDS             6372..8249
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /locus_tag="DQL03_RS03690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00731"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_111674889.1"
                     /transl_table=11
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTTL
                     LDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSSDVKAIQLIRQYE
                     LLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGMRRR
                     VQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHVANRI
                     FELDKAGLTEYQGNYQDYVRLKAEQDERDAANLHKKKQLYKQELAWMRTQPQARATKQQ
                     ARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQ
                     NKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMDETKRVIN
                     YLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLKLLIEKPNV
                     LLLDEPTNDLDIAILTVLENFLANFAGPVITVSHDRYFLDKVATKILAFEEGDIRIFYG
                     NYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKKRMSYLEKQEWAQIEDKIATIE
                     ANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLDI"
     gene            8667..8885
                     /locus_tag="DQL03_RS09355"
     CDS             8667..8885
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995561.1"
                     /locus_tag="DQL03_RS09355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_011106820.1"
                     /transl_table=11
                     /translation="MALLFYYYVRKNQVKKLSQLKNLTEIFRKFIILTINNISAIKAFQ
                     TAGVLFGPVKAANARESSIWFENLTKQ"
     gene            9141..9551
                     /locus_tag="DQL03_RS03700"
                     /old_locus_tag="NCTC12047_00732"
     CDS             9141..9551
                     /EC_number="3.5.1.88"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /locus_tag="DQL03_RS03700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00732"
                     /product="peptide deformylase"
                     /protein_id="WP_002984994.1"
                     /transl_table=11
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMA
                     ANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITVEY
                     LDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(9633..11645)
                     /locus_tag="DQL03_RS03705"
                     /old_locus_tag="NCTC12047_00733"
     CDS             complement(9633..11645)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /locus_tag="DQL03_RS03705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00733"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="WP_111674890.1"
                     /transl_table=11
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGALD
                     NTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANSAL
                     LQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEAS
                     HQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQNYEH
                     YQFLDVAETIAKYAKELQEQHVHAIVVLAHIPATSKDGVVDHEMATVMEKVNQIYPEHS
                     IDIIFAGHNHQYTNGTIGKTLIVQALSQGKAYADVRGTLDTDTNDFIKTPSANVVAVAP
                     GIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNLVTTAQLT
                     IAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQTVQPFGNILQVIQMTGQHIYDV
                     LNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLTTTYTVVVND
                     FLYGGGDGFSAFKKAKLIGAINTDTEAFITYITNLEASGKTVNATIKGVKNYVTSNLES
                     STKVNSAGKHSIISKVFRNRDGNIVSSEIISDLLTSTENTNNSLGKKETTTNKNTISSS
                     TLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     misc_feature    11621..11634
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.33"
                     /tool="antismash"
     misc_feature    11636..11649
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     misc_feature    complement(11637..11650)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     misc_feature    complement(11716..11729)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     gene            11865..12515
                     /locus_tag="DQL03_RS03710"
                     /old_locus_tag="NCTC12047_00734"
     CDS             11865..12515
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /locus_tag="DQL03_RS03710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00734"
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="WP_011054374.1"
                     /transl_table=11
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGF
                     KLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVDLL
                     KSIPGMSVNAEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTIAQD
                     SWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     gene            12518..13186
                     /locus_tag="DQL03_RS03715"
                     /old_locus_tag="NCTC12047_00735"
     CDS             12518..13186
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /locus_tag="DQL03_RS03715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00735"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002984985.1"
                     /transl_table=11
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAY
                     DIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFS
                     LKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLN
                     QGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
                     "
     gene            13195..14427
                     /locus_tag="DQL03_RS03720"
                     /old_locus_tag="NCTC12047_00736"
     CDS             13195..14427
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /locus_tag="DQL03_RS03720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00736"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_002993949.1"
                     /transl_table=11
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRILH
                     LISSNKGKLPDTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDREE
                     AQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLAVSM
                     MLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNELVEL
                     MTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAEDFKSLV
                     LKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIGRRRKRA
                     KLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFKGTITVNY
                     KNDAIVFTVVI"
     gene            14721..15599
                     /gene="mvk"
                     /locus_tag="DQL03_RS03725"
                     /old_locus_tag="NCTC12047_00737"
     CDS             14721..15599
                     /EC_number="2.7.1.36"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /locus_tag="DQL03_RS03725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00737"
                     /product="mevalonate kinase"
                     /protein_id="WP_002984974.1"
                     /transl_table=11
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFPA
                     DKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRAVF
                     SYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIALNGY
                     LIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQLMTQA
                     HSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKISHRLKE
                     EGAVNTWIQML"
     gene            15581..16525
                     /gene="mvaD"
                     /locus_tag="DQL03_RS03730"
                     /old_locus_tag="NCTC12047_00738"
     CDS             15581..16525
                     /EC_number="4.1.1.33"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /locus_tag="DQL03_RS03730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00738"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_002984972.1"
                     /transl_table=11
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFTT
                     TSISFLPDTATSDQFYINGVLQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAAGL
                     SSSSSGLSALVKACDQLFNTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAIYKV
                     ETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLKTNNF
                     EKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMDAGPNV
                     KVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            16518..17525
                     /locus_tag="DQL03_RS03735"
                     /old_locus_tag="NCTC12047_00739"
     CDS             16518..17525
                     /EC_number="2.7.4.2"
                     /GO_function="GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054377.1"
                     /locus_tag="DQL03_RS03735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00739"
                     /product="phosphomevalonate kinase"
                     /protein_id="WP_021299363.1"
                     /transl_table=11
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAH
                     IQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKF
                     GIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVA
                     YTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQV
                     TASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVA
                     ACQKQDAVAKSSGSGGGDCGIALAFNQDARDTLISKWQEADIALLYQERWGEND"
     gene            17518..18507
                     /gene="fni"
                     /locus_tag="DQL03_RS03740"
                     /old_locus_tag="NCTC12047_00740"
     CDS             17518..18507
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /locus_tag="DQL03_RS03740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00740"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_010922169.1"
                     /transl_table=11
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLSTH
                     FAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRL
                     HEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTWKKH
                     LAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRGGDRS
                     YLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVE
                     KYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(18737..20014)
                     /locus_tag="DQL03_RS03745"
                     /old_locus_tag="NCTC12047_00741"
     CDS             complement(18737..20014)
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_process="GO:0016054 - organic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /locus_tag="DQL03_RS03745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00741"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_002984963.1"
                     /transl_table=11
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLPI
                     QTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSGGF
                     KAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTIHLE
                     EKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESLVTTS
                     CEIPVRLLDRDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIATGNDWR
                     AIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPTVSIAHD
                     LLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGATQDEIAP
                     LVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(20001..21176)
                     /locus_tag="DQL03_RS03750"
                     /old_locus_tag="NCTC12047_00742"
     CDS             complement(20001..21176)
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /locus_tag="DQL03_RS03750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00742"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_002993959.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 7.5e-07,
                     bitscore: 25.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSVA
                     PITEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFARS
                     FEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAILVT
                     ADPRILALNEDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQKRENL
                     QLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGNIYTGS
                     LYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQALLDQRT
                     RLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHQRIYHTNDKN"
     gene            21385..22224
                     /locus_tag="DQL03_RS03755"
                     /old_locus_tag="NCTC12047_00743"
     CDS             21385..22224
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /locus_tag="DQL03_RS03755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00743"
                     /product="thymidylate synthase"
                     /protein_id="WP_011017679.1"
                     /transl_table=11
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFA
                     EYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRT
                     IGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVR
                     RVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYD
                     NQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI"
     misc_feature    21415..21429
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.77"
                     /tool="antismash"
     gene            22304..22801
                     /locus_tag="DQL03_RS03760"
                     /old_locus_tag="NCTC12047_00744"
     CDS             22304..22801
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005542 - folic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /locus_tag="DQL03_RS03760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00744"
                     /product="dihydrofolate reductase"
                     /protein_id="WP_002984955.1"
                     /transl_table=11
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAILM
                     GRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGGNK
                     VLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVTALK
                     HK"
     gene            22821..22991
                     /locus_tag="DQL03_RS03765"
                     /old_locus_tag="NCTC12047_00745"
     CDS             22821..22991
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /locus_tag="DQL03_RS03765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00745"
                     /product="hypothetical protein"
                     /protein_id="WP_002984950.1"
                     /transl_table=11
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLASLFLLNAFTNLV
                     NSIHAFYGTLF"
     gene            23121..24350
                     /gene="clpX"
                     /locus_tag="DQL03_RS03770"
                     /old_locus_tag="NCTC12047_00746"
     CDS             23121..24350
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /locus_tag="DQL03_RS03770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00746"
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="WP_002984948.1"
                     /transl_table=11
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEI
                     IKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDD
                     DDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLK
                     LIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVP
                     PQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASY
                     MQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDG
                     VELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVE
                     GKSKPVLETA"
     gene            24360..24959
                     /gene="yihA"
                     /locus_tag="DQL03_RS03775"
                     /old_locus_tag="NCTC12047_00747"
     CDS             24360..24959
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yihA"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /locus_tag="DQL03_RS03775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00747"
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="WP_011184414.1"
                     /transl_table=11
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSF
                     INTILGRKNLARTSSKPGKTQLLNFFNIDNKLRFVDVPGYGYAKVSKSERAKWGKMIEE
                     YLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHES
                     VVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            25107..25850
                     /locus_tag="DQL03_RS03780"
                     /old_locus_tag="NCTC12047_00748"
     CDS             25107..25850
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /locus_tag="DQL03_RS03780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00748"
                     /product="hypothetical protein"
                     /protein_id="WP_002984942.1"
                     /transl_table=11
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSSI
                     EGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQVER
                     DIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFEKLA
                     SQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFDYTRF
                     GKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(25908..28007)
                     /locus_tag="DQL03_RS03785"
                     /old_locus_tag="NCTC12047_00749"
     CDS             complement(25908..28007)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /locus_tag="DQL03_RS03785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00749"
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="WP_010922175.1"
                     /transl_table=11
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEE
                     FQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEIQD
                     TAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSLEAG
                     TQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSR
                     GELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHIT
                     LPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEIAKQKES
                     QEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMG
                     TNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGKRPIGSFLFVGPTGVGK
                     TELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRN
                     PYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFGQQDTE
                     TSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKESLEEIVDLMLAEVNQTTAKKGISLT
                     ITDDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVI
                     RQNDQ"
     misc_feature    28138..28151
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.77"
                     /tool="antismash"
     gene            28385..29068
                     /gene="rpiA"
                     /locus_tag="DQL03_RS03790"
                     /old_locus_tag="NCTC12047_00750"
     CDS             28385..29068
                     /EC_number="5.3.1.6"
                     /GO_function="GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /gene="rpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /locus_tag="DQL03_RS03790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00750"
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="WP_021733827.1"
                     /transl_table=11
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEG
                     LQVVGVTTSSVTSKQAEVLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLME
                     KIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDS
                     RLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLE
                     APTAG"
     gene            29145..30356
                     /locus_tag="DQL03_RS03795"
                     /old_locus_tag="NCTC12047_00751"
     CDS             29145..30356
                     /EC_number="5.4.2.7"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008973 - phosphopentomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /locus_tag="DQL03_RS03795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00751"
                     /product="phosphopentomutase"
                     /protein_id="WP_111674891.1"
                     /transl_table=11
                     /translation="MSKFNRIHLVVLDSVGIGAASDADKFFNAGVADTDSDTLGHISEA
                     AGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGLNI
                     TEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTS
                     ADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRH
                     DYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTLIKTLQ
                     LPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLLLITADH
                     GNDPTYAGTDHTREYIPLLAYSVSFTGNGLIPQGHFADISATVAENFGVDTAMIGESFL
                     SHLK"
     gene            30375..30815
                     /gene="arsC"
                     /locus_tag="DQL03_RS03800"
                     /old_locus_tag="NCTC12047_00752"
     CDS             30375..30815
                     /EC_number="1.20.4.1"
                     /GO_function="GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="arsC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /locus_tag="DQL03_RS03800"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00752"
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="WP_010922177.1"
                     /transl_table=11
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLI
                     ELLQSMGISARELLRTNVPEFEAYGLANQAVAEKDIINAMLADPILINRPIVVTRKGVK
                     LCRPSETLLDILPVPLPSPYIKEDGESVNPIEVKGEKDVIDD"
     gene            30799..31608
                     /locus_tag="DQL03_RS03805"
                     /old_locus_tag="NCTC12047_00753"
     CDS             30799..31608
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /locus_tag="DQL03_RS03805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00753"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_038432917.1"
                     /transl_table=11
                     /translation="MSLMTKINETKDFLVAKGIEAPEFGLILGSGLGELAEEVENPVVI
                     DYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKALG
                     CEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTKVYR
                     NKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVAAHSG
                     LKVLGISAITNFAAGFQSELNHEEVVEVTQHIKEDFKGLVKAILAEL"
     misc_feature    complement(31808..31821)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.2"
                     /tool="antismash"
     gene            32271..32984
                     /gene="deoD"
                     /locus_tag="DQL03_RS03810"
                     /old_locus_tag="NCTC12047_00754"
     CDS             32271..32984
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043096 - purine nucleobase salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="deoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /locus_tag="DQL03_RS03810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00754"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_002990147.1"
                     /transl_table=11
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNM
                     FGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELV
                     LAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNM
                     PERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTF
                     TDMMKVGLETLIAND"
     gene            32977..33765
                     /locus_tag="DQL03_RS03815"
                     /old_locus_tag="NCTC12047_00755"
     CDS             32977..33765
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /locus_tag="DQL03_RS03815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00755"
                     /product="hypothetical protein"
                     /protein_id="WP_002994010.1"
                     /transl_table=11
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERRE
                     LNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRSVS
                     PILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSRNVT
                     TKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSSQAFL
                     ENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(33845..34750)
                     /locus_tag="DQL03_RS03820"
                     /old_locus_tag="NCTC12047_00756"
     CDS             complement(33845..34750)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /locus_tag="DQL03_RS03820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00756"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_002984924.1"
                     /transl_table=11
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMGI
                     TIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFVVN
                     AFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDDNHL
                     TASPLFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMMSQMPH
                     NKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFIKHEKA
                     NLSKMGERFIEYLLEEVTFD"
     gene            34972..35508
                     /locus_tag="DQL03_RS03825"
                     /old_locus_tag="NCTC12047_00757"
     CDS             34972..35508
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /locus_tag="DQL03_RS03825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00757"
                     /product="hypothetical protein"
                     /protein_id="WP_021734032.1"
                     /transl_table=11
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEFP
                     AHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLIDL
                     CQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEEETF
                     IKYYQSPKVPTGEFE"
     gene            35785..36477
                     /gene="pyrF"
                     /locus_tag="DQL03_RS03830"
                     /old_locus_tag="NCTC12047_00759"
     CDS             35785..36477
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /locus_tag="DQL03_RS03830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00759"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_002990139.1"
                     /transl_table=11
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGP
                     DIVRSIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGL
                     GQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAI
                     KAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQ
                     AIKAEWAG"
     gene            36535..37164
                     /gene="pyrE"
                     /locus_tag="DQL03_RS03835"
                     /old_locus_tag="NCTC12047_00760"
     CDS             36535..37164
                     /EC_number="2.4.2.10"
                     /GO_function="GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /locus_tag="DQL03_RS03835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00760"
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="WP_002984920.1"
                     /transl_table=11
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSY
                     PKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDHGA
                     GNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNF
                     KEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            37361..38815
                     /locus_tag="DQL03_RS03840"
                     /old_locus_tag="NCTC12047_00761"
     CDS             37361..38815
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /locus_tag="DQL03_RS03840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00761"
                     /product="amidase"
                     /protein_id="WP_002984918.1"
                     /transl_table=11
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSER
                     FEAALEEAKQRDFSGKPFAGVPIFLKDLGQELKGDLSTSGSKLFKNHHATKTDLFVKRL
                     EALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGISALA
                     TASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTRNLLY
                     YLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALKQAVTWLR
                     EQGHQLVELEEFPVDMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMETMTWAIY
                     QSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVPDSKLMAN
                     LAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEGLPMGIQLI
                     AAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            38933..39796
                     /locus_tag="DQL03_RS03845"
                     /old_locus_tag="NCTC12047_00762"
     CDS             38933..39796
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /locus_tag="DQL03_RS03845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00762"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_172449936.1"
                     /transl_table=11
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWDTIKDKGVLKVATPG
                     TYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLNNF
                     DITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMKVAQ
                     KQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMSDVQY
                     NPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDKKIPVI
                     DTKDVN"
     gene            39825..40475
                     /locus_tag="DQL03_RS03850"
                     /old_locus_tag="NCTC12047_00763"
     CDS             39825..40475
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /locus_tag="DQL03_RS03850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00763"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_047235332.1"
                     /transl_table=11
                     /translation="MINIQLMKDSLGFVLSGLPYTLGISLLSFLTGLVFGLLLALLGRS
                     RQPLLHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYISE
                     VFRSSIEAIDKGQWEAAKALGLPYSLMVKKIILPQAFRIAVPPLGNVIIDMVKSSSLAA
                     MITVPDIFQNAKIIGGREWDYMSMYILVAFIYWIIAFLLERYQEFLENKLALV"
ORIGIN
        1 cgccactgat acaacttatc ataccaaatt aaatgaattg attgaatggt atcaactcac
       61 taattttgat ggtctaataa aatagttatc cacaatttta aaaaaatcag aagaaatatg
      121 tcgatttcaa gacaaaagtt atcaatctca ttaaattatc tgtggaaaag ttaatttaaa
      181 cgttcgtgtg ctataataga aacatagaaa atgaataaaa aaggatatgt ggataatgac
      241 aaaaaagaaa ggtaagcttg tacttatcag tctttttgtt ctagcagctt gtttaggagc
      301 ttatagtgca atgagacaat ctcataaaac ttcaaacgtg tcagctgaga ctatcgccag
      361 ttcttcaacc cgacatttta ttgatgaaat tggtccaact gctagtacta ttggtcaaga
      421 acgtgatctt tatgcgtctg ttatgatagc acaagcgatt ttagaatcaa gtaatggtaa
      481 atcaagtcta agtcaagcac cctatcataa cttctttggc atcaaagggg cctataatgg
      541 ttcgtcagtt accatgtcaa cttgggaaga tgatggtaat ggcaatacct atacgattga
      601 tcaagccttt agagcttatc caagtattgc agactccctt aatgactatg cggacttgct
      661 aagttctagc acttatatag gtgctagaaa atcaaacacg ctatcgtatc aagatgctac
      721 agcagctcta actggcttat acgctacaga caccagttat aacttaaaac taaataatat
      781 tattgcaacc tatggtttga cggcttatga tgttgctaat agcgcagctc aagaaactgg
      841 tctagcaact tcgggttatg tttggaatga gtatcgtcgt aattacactg atgcggagac
      901 cctagcagtt gatgaggctt gggctaaacg catgacttat taatgtaaca ctaacaacaa
      961 tctgcttgca ctgaccccaa aaaagctgga tactctattt taagtaaagg atttagttct
     1021 gtattgtaca gaactaaatc cttttagttt tactttgata tgtttatcgt tgtaataatc
     1081 aatgccgttt gtaatcgctt attctaagtc ttctagtgat ttatagttat tctcataacc
     1141 atagaacatt tctgacttta agatgccaaa gaaagattcc atcatgctat tgtcaggact
     1201 gtttctttta cgtgacatag acggacgaat tcctttagag tttaggaaat gatgataata
     1261 gttgtgttga tattgccaac cttgatcact ctatcatata gttccatcat agcatttatt
     1321 tggagatgtc tttttccatt attggtttaa tgtgatttaa gcaaggttat tagctaaact
     1381 taatgccaga caaaaacacc ccaattatta gattttttgt ctaacttttg gggcgcaatt
     1441 caatctgagc agttttagat ttggtatcaa tgttattata ggtcaattga tcatatttat
     1501 ccaaagcttt tagcttattt agtccaaaga taaatatcaa aatggctgaa atctttcatg
     1561 tttatagtct tattgtcttt atattttttt aagacatcag atctggtgct attgggtttt
     1621 gcgtcatata aattgatttt ttcatgtttc ctatttttac tgtgaattta taaactcccc
     1681 cttatataag gagacttagt caaatgaatt tcttttgatt ccatcaaaaa ttttcttatt
     1741 ttaaaatcga actcttgaat cgtaacaata tccttatcga tttttatagg atttattaat
     1801 gttttttgct gttgcccatc tataaaaaaa ttccctgcaa tagtattagt ccttagaata
     1861 ccatcatctg ttgaaggtat tctttcttat tgatacgctt taattggtct gattccaact
     1921 atcttgccct gttgaaagtg taaataaccc tagtacttga gcaccaatat tatcttcttt
     1981 tatttcttta gcagaaatag ctacttttcc agcggaatta acaccaacaa agtatttctt
     2041 cataccaata gatgcattac tatcagagtc tgttacataa atagctttaa ggttcccgtt
     2101 agaatcaaag tcagctcccc acaggtttat aacatggttg atgcgtacgt tagcgtaggt
     2161 gtgtgatagg cctagagcct tgccttcggt taactctttc ttaatgagat cactgatttc
     2221 tttgagagtt ttttctttaa aatcatgacg acttgtcaat agcttacttt gatcacctct
     2281 tgtaaatacg gcgtcaaaaa taccacctcg gcgatctttc tcttgatagg ttctattgac
     2341 atcagtagtc tgtgtcttat aaacatttaa gtaatagcca ttgataaaca tatctaaaac
     2401 aagatcaggc ataactccaa ttcggcgtgc tgacaaaccg gggaaagctt tatctcggaa
     2461 ataattaaaa agctcgctat ttgtttggtc acctttagta ttaataactt ttcttacatc
     2521 caataattct tgatcaccaa acatgatttt ttgtttatct gggtgttttt ttagatatgc
     2581 ttcaattttt tctttgtttt gatcgaacca ccagtgaagc atattccctg ctgtggcagc
     2641 cccgcaaaga agatcgtctt ttccattgaa tgttttggta atatcatacc atccttggtt
     2701 agcaacataa ggagcgtgaa aaacatcttc gccttgagtg aattttgctg gaggagtaac
     2761 tcctttggtc caaacggaag taacatgata aggtgttact tccgaatatc taatctcttg
     2821 attagcagaa aaactatctg ctataacacc acgatctacc gatagagcaa ataaagtcac
     2881 tgctgccaat actgcagctg aagttgaata gcatcttttt ctcataagag tacctttttc
     2941 tatacaattt tattataaaa agattatatc atatagacat ctattgttgc aattttttaa
     3001 aataatattt aataaacgta aacaagcgat tgacaatgga gatatcacaa gagacacagt
     3061 agtggttgtg cttaaaaatg gacggttttt tgatgatatg ttgctgcatg aggaagtgag
     3121 caataggaga gctgtgatag aagaaagaga ggaagaagcg ttgatgaaat tagacaaata
     3181 aaaaaaagac ctcatccaga agaggtcgtg gtataactgg ggacgatagg ttcaattgat
     3241 aaaaaatctt gttagcttac gatctatgtt gttttgaatg cctttaactc aacatcgtta
     3301 atggattttg agataaaaaa ataaatccaa tagtctggta ctttcctatt ttttgtctgt
     3361 taaaacgttt ttattttata atggataaaa ggagaagaag ggcggagcga tgattaagct
     3421 ctatgggttt aagtatgggt tagttggaga ggttttgcgg cggattgaac gcctaggatt
     3481 tacgtttgag cgattagagc taagacaagc tagttcgaaa tacttggcta agcatgatga
     3541 ggccttaatg ataaaccttt ttatcctgga cttaaaactt acctgaccag tggttctgtt
     3601 ttaattgagg tgcagtacaa gaccactaac gggtgttttt ttgatataat gtcagtataa
     3661 ggacgactaa atataaatag gtgaaaaaat agatatctgt tcgagagata gcactgttta
     3721 aaacgttatg caaaaatagt agtttagggg ctactttaat aattttcaaa tctatgctat
     3781 aatggatcat attgatacca aggagaataa aaaatgcaat tagttcgtga aaaagaattt
     3841 gtcaaccagt accattatga tgctagaaat ttagagtggg aaaaagaaaa cggaacacca
     3901 gagaccaatt ttgaagtgac ttttcagttg attgataaag atgagcagca aaaagaaaca
     3961 gtaattgtat ctgtattgca atttgttatt gtcaaagaag aatttgttat tagtggggtc
     4021 atctcacaaa tggttcgtat tttagatcgt ttagtggata aaccaagcga atttacgcaa
     4081 gaggaagttg aatccttagc tgctcctttg ctagacatgg ttaagcgatt gacttatgaa
     4141 gtcacagaaa ttgccttgga tcgtccaggt attcatttgg agtttaaaaa ttaatgaaat
     4201 tagcagtaat tactgacagt acagcaacac taccaataga tctgaaacaa gataaagcta
     4261 tttttagcct tgatatacca gttatcattg acgatgagac ctattttgaa ggtcgaaatt
     4321 tgagtataga tgatttttat caaaagatgg ctgactccaa aaatcttccc aagacaagtc
     4381 agccaagttt atctgaacta gataatcttt taggactttt gtcttctaag ggttatacac
     4441 atgttattgg cttgttctta gctggaggaa tctcaggctt ttggcaaaat attcaatttt
     4501 tagctgaaga acatcctgag attgaaatgg catttccaga cagtaagatc acatctgctc
     4561 ctttaggtag tatggtaaaa aatgtgctag attggtcacg tcaaggaatg acatttcaag
     4621 ctattttaaa caagctgcaa gaacagattg atgggacgac agcctttatt atggttgatg
     4681 accttaatca tctggttaaa ggcggacgcc tgtcaaatgg gtctgctctt cttggaaatc
     4741 ttttgagtat taaacctatt ttacgctttg atgaagaggg aaaaatcgtt gtttatgaaa
     4801 aagtgagaac agaaaagaaa gccatgaaac gcttggttga gattttaaat gacttgatag
     4861 cagacggtca gtataatgtg tctattattc actcaaaagc acaagacaaa gctgattatt
     4921 tgaaacgact cttacaagac agtggttatc aatatgacat tgaagaggtt cattttggag
     4981 cggtgattgc tactcattta ggagaaggag ccattgcatt tggcgtaaca ccgaggcttt
     5041 aattgtcgat tagaaaaaat agttaattgc aagaatcact aaaacaataa caaaatgtga
     5101 tagaacccaa gtagcctaat cacactttag attgggctag ttggatgata ggttagaaaa
     5161 caacgtatga aattaatgac aatgccttct gagtttcaga aggctttacc catattgact
     5221 aaaataaaag aagctggtta tgaagcctac tttgtgggag gaagcgtcag agatgtttta
     5281 ctcgagcgtc ccattcatga tgtagatatt gcaactagtt cctatcctga agagactaaa
     5341 gcgattttta acagaactgt cgatgttggc attgaacatg gcactgtttt ggttttggaa
     5401 aatggtggtg aatatgaaat tacaaccttt aggacagaag atgtctatgt tgattatcgc
     5461 cgtcctagtc aggtttcttt tgtgcgctct ttagaggaag acttaaaacg aagagacttt
     5521 accgtcaatg ccttggcctt ggatgaaaat ggtcaagtta ttgataaatt tagaggactc
     5581 attgatttaa agcaaaaacg gttacgagca gtgggtaaag cagaggaacg ttttgaagaa
     5641 gatgcactac gcattatgag aggctttcga tttgcggcga gtctggattt tgacattgaa
     5701 gctgcaactt ttgaagctat gaggagccat tcacctctat tggaaaagat ttctgtggaa
     5761 cgctctttta ctgaatttga taaattattg atggcaccgc actggcgaaa agggatttct
     5821 gccatgattg cttgtcaggc ttatgactat ttaccaggct tgaagcagca ggaagcaggc
     5881 ttgaatcatc tgatagtttc tttgaaagat aactttacct ttagtgatca tcaccaagct
     5941 tgggcttatg tgatgattag tttagccatt gaggatccta aaagcttcct aaaagcatgg
     6001 aagacttcaa atgattttca gcgttatgtc acaaagttga ttgctcttta tagaattcgt
     6061 caggaaagat cttttgaaaa attggatatt taccagtacg gcaaggaaat ggcaagtcta
     6121 gtggaaggcc tccgaaaagc tcaaagctta tctgttgaca tggaccacat tgaagcttta
     6181 gatcaagcgc tagccattca taacaaatac gatatcgtcc ttaatggttc tcacctgatt
     6241 aaggattttg ggatgaaacc aggtcctcag ctagggctta tgcttgagaa agttgaatta
     6301 gcgattgtag agggacgcct agataatgat ttcactacaa ttgaagcatt tgttagagag
     6361 gaattagcaa catgagccat tttttggtgg agaaattgac aaaaacggtg ggagataaaa
     6421 cagtctttca ggatatttcc tttattattc atgactttga ccgtattggg attattgggg
     6481 ttaatggaac aggaaaaaca actcttttag atgtcttgtc gggaaggctt ggttttgacg
     6541 gagaccattc accattttct aaagccaatg attacaaaat cgcttactta acacaagatc
     6601 ctgaatttaa cgatgcagcc tctgttttag atacggtatt gtcatctgat gttaaggcga
     6661 ttcagctgat tcgtcagtat gaactattga tggcgaatta tactgaagat aaacaagaga
     6721 ctttagagtc cctcatgtct gaaatggatc gcttagatgc ttggtctatt gaaagtgatg
     6781 tcaaaacagt cctatcaaaa ttaggcatca cggatttgga acaaaaagtg ggagatctat
     6841 caggtggtat gagaagacgt gtccagctag ctcaagtatt gctaggagct gctgacttac
     6901 tcctattaga tgagccgacc aaccatctcg atattgatac catcgcttgg ttaacaacct
     6961 atctcaagac agctaaaaaa accgtccttt ttattaccca tgaccgttat ttccttgatc
     7021 atgtggctaa ccgtattttt gaattggata aagctggact gacagaatat caaggcaatt
     7081 accaagacta tgtgcgctta aaagcagaac aagacgaacg agatgctgct aatttacaca
     7141 agaagaagca actctataaa caagaattag cctggatgag gacgcagcca caggcgcgtg
     7201 caaccaaaca gcaggctaga atcaatcgtt tcactgactt gaaaaaagaa gttcaccaag
     7261 acagttctgc ggataagttg gagatggctt tcgaaacgag ccgaattggg aagaaggtga
     7321 ttcactttga agacctttct tttgcttatg gcgaccgaca gttgattaag gattttaatt
     7381 tgattattca aaataaagat cgtattggaa ttgttggaga taacggcgtc ggaaaatcta
     7441 ccctgttaaa tatcatcaac ggtgatctca aaccaacttc tgggaagctt gatattggag
     7501 atactattcg tgtaggttat ttctctcagc agctcaaaga tatggatgag accaaacggg
     7561 tcattaatta ccttcaagaa gtggctgatg aggttaaaac aagcgtggga acaacgagta
     7621 tcagtgagct tttagagcaa tttctttttc cgagatcaag tcatggcacg ctgattgcta
     7681 aattatctgg tggggagaaa aaacggctct acttgctaaa actgctcatt gaaaagccaa
     7741 atgttcttct ccttgatgag ccaacaaatg atttagacat tgctatcttg acggtcttag
     7801 aaaacttttt agctaacttt gcaggaccag tcattacggt tagtcacgat cgttatttcc
     7861 tagacaaagt agccactaag attttagcct ttgaagaagg cgatattcgt attttttatg
     7921 ggaattacag tgattacctt gatgaaaaag cttttgaaaa agaaacagtt gaggctgact
     7981 tagctaaagc aatagtcact gaagaagtgc cacttcctcc gaaagaggag aaaaagcgca
     8041 tgtcctacct tgaaaaacaa gaatgggctc agatagaaga taaaatagca actattgagg
     8101 ctaatattga agaaattgaa aaccaaatgt taactgtagt tagtgattat ggccagttag
     8161 ctcaattaca aaaggaactc gatcagcgca ataatgattt attattggcg tatgaacggt
     8221 ttgagtattt gagtggacta gacatataag tatactatgg taatgttatg tttataataa
     8281 acaagtgata atagaaaaga agtgctcttg cactgagccc caaaagttgg ctactctatt
     8341 tgaagtaaag gatttagttc tgtgttgtag aggactaagt ccttttcgtt ttattttgat
     8401 acgtttattg ttgcaataat cgatgataat agtaggtaga acgagtcaat ttagccgttc
     8461 ttaaaagaaa atctaatcag aactcgtctt tgtccattct ttataatggt tttttgtctt
     8521 cttctttgca gagatgcttc tttcaaacgg agttccctcg gtttttttag cgctaaatat
     8581 ctagcttatc ttcatagctt aatgtcatac aaaaacaccc caaacgttag atttttttat
     8641 ctaacgtttg gggtgtagtt tacattatgg cgcttctttt ctattattac gtgaggaaaa
     8701 atcaagtaaa aaagttaagt caactgaaaa acttgacaga aatattcaga aaatttataa
     8761 tactaactat taacaacata tcagctatta aagcatttca aacagcaggt gttttatttg
     8821 gacctgttaa ggctgcaaat gcaagagaaa gcagtatctg gtttgaaaat ctcacaaagc
     8881 aataacgatc tctcttagac acttgaagaa gcagacagta aattcgataa tattgtgatg
     8941 agaatttagc aacaatctgc tgatgcaggt caatttttat ttagtactca tattgcagaa
     9001 tttcataaag ttgcccaaga tatcttgaaa taaggaatca cctgatgttt taaacagatg
     9061 atactaagtc tatcctatgg tgataatagt ccattgaaca tgtagtttat gaattaaaaa
     9121 gaaggtttaa ggagataaga atgattagag aaatcataac agatcatttt ttattacagc
     9181 aaaaagcgca agtcgccaag aaagaagatc tatggattgg ccaagattta caagatacct
     9241 tagcctttta tagacaggaa tgtcttggga tggctgccaa tatgattggt gaacaaaagc
     9301 gcattgttat tgtgagtatg ggatttattg atttggtgat gtttaatcct gtgatggttt
     9361 ctaaaaaggg aatttaccaa actaaagaat cttgtttgtc gttatctggc tatcgcaaaa
     9421 cacagcggta tgataagatt actgttgagt atttggacca taattggcga ccaaagcgat
     9481 taagcttaac aggcttaact gctcaaatat gccagcacga attagatcat ctagaaggta
     9541 ttttaattta acaaaaaacc tagagtagga cgctttaggt ttttttggca aagatgcctg
     9601 attatataag ggtgatcgat tactagtaaa cgctaggatt tccttttttt aataaaagcg
     9661 tttagtccac ctaagcttat caaggcaagg attgtcataa taggagacat tttataattg
     9721 tcccctgtta ttggaagagt ggaactagag atagtatttt tgtttgtcgt tgtttctttt
     9781 ttgccaaggc tgttattagt gttttcagta gaagtcaaaa ggtctgaaat gatttcacta
     9841 gacactatat tgccatcacg atttctaaaa accttactaa tgatactgtg tttaccagca
     9901 ctattaactt ttgtcgaact ttcaaggttt gaagttacat aatttttaac cccttttata
     9961 gtagcattaa cagttttacc tgatgcttct aaatttgtga tatatgtgat gaaagcttca
    10021 gtatctgtgt taatagctcc gattaattta gcttttttaa atgctgaaaa gccatcacca
    10081 ccaccataaa gaaagtcgtt gacaacaacg gtgtaagtag ttgttaagtt aatttcttca
    10141 ccattgtctt tataaacctt aactatcttg aagggggtat cagagttctt aggatcatta
    10201 tctgtataag tgtatgttaa acctgacatt tgaagaaaat aggtctggtt ttcatcgtat
    10261 tgctgattta ggacatcgta aatgtgttga ccagtcattt gaatgacttg aaggatatta
    10321 ccaaatggtt gtacagtctg tgcagctccc caggtgatgg tccggtcatt tttgacaact
    10381 aggtcacttc gaataccacc attattggtc atagcaaagt caacagttgg aaaagttttc
    10441 ttagcaatag taagctgagc cgttgttact aagttaccga caggagattc tttatcaata
    10501 ttttctgttt tagaaatagt tgaagaatta gttgcagttc cgatttttcg ttcagtaact
    10561 gttttaacaa tatcattagc atgatttatt atagctttga tatctgaatt ttctgttttg
    10621 atacctggtg ctacagcaac aacatttgct gatggagttt taataaaatc attggtatca
    10681 gtatctagcg taccacggac atctgcataa gcttttcctt gagagagggc ttgaacgata
    10741 agtgttttac cgatagttcc attagtgtat tgatgattat gtcctgcaaa aataatatca
    10801 atgctatgtt cgggatagat ttggttcact ttttccataa ccgtagccat ttcatgatca
    10861 acaacaccat ctttacttgt tgcaggaata tgagctaaaa ccacaatagc atgaacatgt
    10921 tgttcttgca gttctttagc atatttggca atggtttcag ctacatctaa aaattgatag
    10981 tgttcatagt tttgctttaa aacgagattt ggaatctctg tagtcacaac accaatgaag
    11041 ccaatcttaa cgattttgtc attaatggct atgtctttta tagcataagg tttccaacca
    11101 taggggatat cattagtttt tttatcaatg acattagcaa tgacgatggt ttgatgcgaa
    11161 gcttcgtgct catattgttt ggtgatatca ttaattgttg attcaggatc aggcgcttga
    11221 cctgtcatga tacggttaaa ttcatctagt ccttcgtcaa attcatgatt accgagagtg
    11281 ccatattcaa atttcatttt gttaaagact ttcacagtag gctcatcttg taaaagtgca
    11341 gagttagcag gactggctcc gaccatatct ccagcttgaa cacgtatact tgttccatct
    11401 tgatttgctt gcttgaaatc tatctcagcg tcatccatat aagcacctaa ttgagcagcc
    11461 gtcccagcat ttggtatttt accacttggt gtgtaagctg ttccggtatt atcaagagcg
    11521 ccgtgaaaat cattgacgcc aaggaattgc acatcaactt gatctgcttg aacgtctgta
    11581 actaatagag taaaactagt caggatactc aatacactac tttttaaaat aaaatatttt
    11641 ttcataaaat ctcctaataa gttaacgtaa tcgttataga tcaagtttac tatgtttttg
    11701 tttgtaattc aatggtattt ttaaaaaata acgcacaaaa aatatatgaa agcgatttaa
    11761 aaacaaacga tacagatcat tttcagttat atagttagaa ataaagataa ccgatcattg
    11821 cagagattta agcatttgtt gagaaaattt gttataataa gcgtatgaaa gaaagactag
    11881 aacattattc taccagctct atatatagcg gatttgaagt gtacttgccg ttggtactac
    11941 agacaataac agatgtgatt attgctgaga atatcaaaag caaaaaagaa acggggttta
    12001 aactatacga acactttaca tcccgtatta aatcggaagc ttcgatgatt gaaaaatgtc
    12061 aacgcaaaca gcttcctcta acaagcaaat ctgcgttaaa aatcattaaa gatagtatcg
    12121 gtattcgcat tatttgtggt tttattgatg atatttatcg gatggtagac ttgctcaaaa
    12181 gcattcctgg tatgtcagtt aacgctgaaa aagattatat tttaaatgcc aagcctaatg
    12241 gctatagatc atatcatctc attttggaat tagaaacaca ttttccagat attttagggg
    12301 aaaaaaaagg atgttatttt atagaagtgc agttgcgaac cattgctcaa gactcttggg
    12361 ctagcttgga acatcaaatg aagtacaaac atcaagttgc taatgcagaa atgattacaa
    12421 gagagttaaa gcgttgtgca gacgagttgg catcttgtga tgttaccatg caaaccattc
    12481 gtcaattgat tcaagaaacg acggaggaag agtaaccatg aaaattttgt tagctgaaga
    12541 cgaatggcag atgtctaatg ttttgacaac tgccatgact catcaaggtt atgacgttga
    12601 tgtggttttt aacggtcaag aggcaattga taaagccaaa gacaatgcat atgatattat
    12661 gattttagat atcatgatgc cgattaagtc tggcattgag gctttaaagg agattcgcgc
    12721 ttcaggaaat tgctcacata ttattatgct gacggctatg gcagaaatta atgaccgtgt
    12781 taccggacta gatgcgggag ctgatgatta tctgactaaa cctttctcat taaaagaact
    12841 tttagctaga ttaaggtcga tggaaagacg agtagaaagt tttactcctc aggtattaca
    12901 atttgctggt gtcacattga atattaatga gcaagaattg agtgccggta atgctatacg
    12961 attagcttct aaagaaggta aattaatggc ctttttaatg ttaaatcaag gaaagtactt
    13021 ggatactaaa acactttacc aacatgtttg gtcagaccaa gaagattatg atacttctat
    13081 tgtttgggtt tatatttctt atcttcgtca aaaattatta gctattcaag caaatgtcat
    13141 tattgcaggt gataaagata ctagctattg tttattagaa aaataggagg tgacatgttt
    13201 aatcgtatcc gtattcgttt tatcatgatt gcttctattg ccatttttat tattttaagt
    13261 tcaattgttg gtattattaa cacggcacgc tgttaccaaa gtcaacaaga aattaaccgt
    13321 attttacatt taatttcctc aaataaaggt aaattacctg acactacgga aagctctaaa
    13381 cgacttggaa cgaaactgtc tgaagatagc ctaagccagt ttcggtatta tagtgtcatt
    13441 tttaatgcta atggacatct actttcttct aatactgcta atatttcagc tttagataga
    13501 gaagaagccc aatattttgc tagacttttt gctaagtctg gggaagaaaa aggcagttac
    13561 cgtcaccaag atagtgttta ttcgtacttg attactcagc tgccaaatga agaaaaactg
    13621 gttgtaattt tagatactac cttttatttt cgtagtgtag gagatttatt agctgtttca
    13681 atgatgttgg cctttggagg atttatcttt tttgttgttt tagtgagtct tttttccggt
    13741 atggtcatca aaccttttgt ccaaaattat gagaagcagc gtcgctttat tactaatgca
    13801 ggccacgagt taaaaacacc actagccatt atctcagcca ataatgaatt ggtcgaatta
    13861 atgactggag aatcagaatg gaccaagagt acaagtgatc aggtgaagcg attgacaggc
    13921 ttgattaatc aaatgattac tttggctcgt ttggaggaac agccagatgt ggtattacat
    13981 atggtagact tttcagctat tgctcaagat gcagctgaag attttaagag tctggttttg
    14041 aaagatggta aacgttttga tttgacgatt cagccgaata ttatgattaa agcggaggaa
    14101 aagtcattat ttgaacttgt gacaatttta gttgataatg ccaataaata ttgtgatcct
    14161 aaaggcttgg tcaaggtatc tttaaccact attggaagaa gacgaaaacg agcgaaatta
    14221 gaagtttcta atacctattt ggaaggaaaa tccattgatt acagccgctt ttttgaacgc
    14281 ttttatcgcg aagacgaatc ccataatagc aaagaaaaag gttatggaat tggtttatct
    14341 atggcagaaa gtatggttaa gttatttaaa ggaacgataa ctgtaaatta taaaaacgat
    14401 gctattgttt ttacagtggt gatttgactt aaacattttt cagtaccttt agctagtaat
    14461 aatgtctagg taaaggtaat aaacgatgct taaccagccc atgaggctgg tttttaacgt
    14521 ttaatttagt agaagagtga ttaaagaagg tagtttgaaa taagaaaatt tttgttatga
    14581 tcctaaaaag agtagatagt ctttattgtt aatttcggtg aagaaatgat tttaaaaaga
    14641 tatatcatcg cattttctaa tcatttagtg taaaatagta aggtaaaagt ttagaagaat
    14701 tagtaatgaa aagataaaaa atgaacgaaa acattggata tggtaaggca cacagtaaga
    14761 tcattttgat aggtgagcat gctgttgtgt atggctaccc agctattgct ttgcctttaa
    14821 cagatattga ggtggtttgt catatttttc cagctgataa gccattggtc tttgattttt
    14881 atgatactct atcaacagcc atttatgctg ccttggatta tttgcagcga ctacaagaac
    14941 caattgctta tgagattgtt tcacaagtgc cacaaaagcg tggtatgggg tcttcggcag
    15001 ccgtttctat tgcagctatt agagccgttt tttcttattg tcaagaaccc ctctcggatg
    15061 atttgttgga aattttagtc aacaaggcag aaattattgc ccacaccaat cctagtggtt
    15121 tagatgccaa gacatgcctt agtgaccatg ccattaagtt tatccgaaac attggctttg
    15181 aaactatcga aatcgcctta aatggttatc ttatcattgc agatacaggg attcacggtc
    15241 atacacgtga ggccgtcaat aaggtagcac agtttgagga aacgaatttg ccctatctgg
    15301 ctaaactagg agctttgaca caagcccttg aaagagcgat taaccaaaaa aataaggttg
    15361 ctatcggtca gctcatgaca caagcgcact ctgctttaaa ggccattggc gttagcatca
    15421 gtaaggctga ccaacttgtg gaggctgccc taagagcagg tgctttaggc gctaagatga
    15481 caggcggtgg cttgggtggc tgtatgattg ccctagcaga taccaaagac atggccgaaa
    15541 aaatcagtca cagattaaaa gaagaaggag ccgtaaacac gtggatccaa atgttataac
    15601 cgtaacatcc tatgctaaca ttgctattat caaatattgg ggaaaagaga atcaagctaa
    15661 gatgattcct tcgacctcta gcatttcttt gactttggaa aacatgttca ccacaaccag
    15721 catttccttc ttaccagata ctgcaaccag tgatcagttt tacattaacg gtgtcttgca
    15781 aaatgacgaa gaacatacca aaatttctgc tatcattgac caatttcgcc aacctggtca
    15841 ggcttttgta aagatggaaa ctcaaaataa tatgccaaca gctgcaggtt tatcatcaag
    15901 ttctagtggc ttatcagcct tggttaaagc ctgtgaccaa ctatttaaca cccagctaga
    15961 tcagaaagct ttagctcaaa aggctaagtt cgcctcagga tcatcttctc gttctttttt
    16021 tggcccagtc gctgcttggg acaaagatag tggtgctatt tacaaggttg agactgactt
    16081 gaaaatggcc atgattatgc tggtcttaaa tgctgcgaaa aagccaattt ctagccgaga
    16141 gggcatgaag ttatgccgcg atacctcaac tacatttgat gagtgggtag aacaatcggc
    16201 aatcgattac caacatatgc ttacctatct caaaactaat aattttgaga aagttggtca
    16261 gttaacagaa gctaatgcct tggccatgca tgccacgaca aagacagcca atcctccttt
    16321 ttcttaccta acaaaagagt cttaccaggc tatggaggct gtgaaagaac tgcgtcaaga
    16381 aggttttgct tgttatttta ccatggacgc aggtccaaat gtgaaggtcc tatgtttaga
    16441 aaaagacttg gctcaactgg cagaacgact tggcaagaac taccgtatta tcgtttcaaa
    16501 aacaaaggat ttaccagatg tctaattatt gtgtgcaaac aggtgggaaa ctatacctca
    16561 caggcgaata tgctatctta acaccaggac aaaaagcctt aattcacttt attccactga
    16621 tgatgacagc agaaattagc ccagcagccc atattcaatt agcttcagat atgtttgccc
    16681 ataaagcggg catgacaccc gatgcctctt atgcactgat tcaagcaacg gttaaaacct
    16741 ttgctgacta tctaggacag tcgattgacc aactggagcc attttcccta atcataacag
    16801 gaaaaatgga gcgcgatggc aaaaaatttg gcattggttc aagtggtagc gtcaccctct
    16861 taaccttaaa ggccttatcg gcctattatc agatcacttt aaccccagag ttactcttta
    16921 aactagcggc ttataccttg cttaagcaag gagataatgg gtctatgggg gatattgcct
    16981 gtatcgctta ccagacttta gtcgcctata cctcctttga ccgagaacag gtcagtaact
    17041 ggctgcagac catgccctta aaaaaacttc tcgtcaaaga ttggggttac catatccaag
    17101 tcattcaacc agccctgcct tgtgactttt tggttggctg gactaaaata cctgctattt
    17161 caaggcagat gattcaacaa gtgacagcga gcattacccc agctttctta agaacaagtt
    17221 accagctaac gcaatcagct atggtagctt tgcaagaagg tcataaggaa gaactcaaga
    17281 aaagtttagc aggagcaagt catctcctaa aagagcttca tccagctatc taccatccta
    17341 agctagtaac cttggtagct gcttgtcaga agcaagatgc tgttgctaaa tcttcaggtt
    17401 ctggtggtgg agattgtggc atcgcgcttg cctttaatca ggatgctaga gataccctta
    17461 tttccaaatg gcaagaagct gatatcgcat tactttatca agaaaggtgg ggagagaatg
    17521 actaaccgta aagatgatca catcaaatat gctctcaagt accaatcgcc ttataatgct
    17581 tttgatgaca tagaactcat acaccattcc ttacctagct atgatttgtc tgatattgat
    17641 ctcagtactc attttgctgg gcaagacttc gactttccct tttacatcaa tgccatgaca
    17701 ggaggaagtc aaaaaggcaa agctgtcaat gaaaaattgg ccaaagtagc agcagcaaca
    17761 gggattgtca tggtgacagg gtcttatagc gctgctttaa aaaatcctaa cgacgattcc
    17821 tatcgtttac atgaggtggc agataacttg aaactagcca cgaatattgg tctagataaa
    17881 cctgtggcgc taggacaaca aacggttcaa gaaatgcagc ccctcttttt acaggttcat
    17941 gtgaatgtga tgcaagagtt gctgatgcca gagggtgagc gcgtctttca tacctggaaa
    18001 aaacacctcg ctgaatacgc tagtcaaata ccagttcctg tcattctcaa agaagttggt
    18061 tttggcatgg atgtcaatag tatcaagcta gcacatgacc taggcattca aacctttgat
    18121 atttcaggta gaggaggaac ttcatttgct tacattgaaa atcaaagagg gggagaccgc
    18181 tcttacttaa acgattgggg acaaaccacc gttcagtgct tgctaaatgc acaaggactg
    18241 atggaccaag tggaaatctt agcttcgggt ggtgtcagac accccttgga catgattaag
    18301 tgttttgtct taggagcacg tgcagtggga ctctcacgca ccgttttaga attggtcgaa
    18361 aaatacccaa ccgagcgtgt gattgctatc gttaatggct ggaaagaaga attaaaaatc
    18421 attatgtgtg ctcttgactg taaaactatt aaagaattaa agggagtcga ctacttacta
    18481 tatggacgct tgcagcaggt caattaggct tcatcacctc tacaatagtg tcacctacta
    18541 caaagatgat agagcttttt tagaacataa tataaaatat ttataaatac ctcatcaaac
    18601 tcagaataga gtagatgagt aaatagagta tgttatggag actatttcta agacttgtat
    18661 gtatagaaac aaagattaaa cacccatgta aaccaattgt ttacatgggt gtttgcctta
    18721 tattagttgt ttaaatctaa gactgtctta gctgggataa gtaaaaatgt gctttttcta
    18781 gatttattgg tttatcagct agtaaagcat taactaaagg agcaatttcg tcttgggttg
    18841 cccccgccaa aagagctaat gatttcgcat gtagtttcat gtgaccagct tggatgccag
    18901 atgaggtcag agcttttagt gcagcaaagt tttgagctaa ccccacagat gcaatcaatt
    18961 gggctaatgt tttggcatca ggttgattaa gaagatcatg tgcgatagaa acagtagggt
    19021 taagcccgat agatcccccc ttactagcaa taggcatagg gagggtcatt tggccaagca
    19081 gaacttgttt atcttggtca aaatgccact gactaagtcc ttgatagcta ccatttcttg
    19141 aggcataagc atgggcccct gcttcaatag cacgccagtc atttcctgtg gctattacca
    19201 ctgcatcaat accattaaaa atacctttat tatgagtagt agcccggtaa ggatctactt
    19261 gagctagtcg gctggctagc tctatttttt gagctaactg tagggatttt gttttatcgc
    19321 gatctaaaag gcgcacggga atctcacaac tagtagtaac aagcgactct gttgcgtaat
    19381 tagataaaat cgccattaga caatgcccct tagacagtct tgttaaatca ggaacaagag
    19441 cttccatcat agtattgacc atatttgctc ccatagcttc ttgggtatca acagtcagat
    19501 agaaaatcaa aaattctcct ttttcttcca aatgaatggt tctagcgcct ccacctcttt
    19561 taacaatgga aggataagct ttatttgcca atgcaattag cttttttgtt ttatgaagga
    19621 tggcggcttt agcgttatct atttggtcga tatcgtaaag aacaatttga ccaatcattt
    19681 gtcggtttag ggtttgagct ttaaaaccac ctgagcgttt gattagtttt gctgcgaaag
    19741 atgctgcagc aacaacagaa ggttcttccg tgacaaaagg catctgataa gttgaaccgt
    19801 tgacaagaaa atcaggagct atgctaaagg gcaaagccaa tcgtcctaag acattttcag
    19861 tcatttgatt agctgtttgg ataggcaaaa gaacgtctgt tttgagttga tttaagtttt
    19921 cagcattaag tagtttaaat ttttcgataa gttggaggcg ttcttcgaat gttttctttg
    19981 aaaaaccgct ccagttaaga ttagtttttg tcattggtat gatagatcct ttgatgctcc
    20041 ttgatggctg ttagagcaaa ttttccagtt aagtaaatgt caaaattggc attaccatta
    20101 tcatctaatt ggacttgttc gtagaaaagg tcttcgtatt tagaaacgga aagacgtgtt
    20161 cgttgatcta gtaaagcttg tcgattagtc attaacattt tatcgtaccc agcaactaac
    20221 tgaccggaat aaaattcact tacggcaccg gaaccatagc taaaaaaacc aattttatct
    20281 ccagattgta atactttact attttcaagt aaagataaca atcctagata aagtgagcca
    20341 gtataaatat ttccaatttg tttgctataa gtaatagaag cttgaaaggc ttctattagt
    20401 ttttccctgt gttcaggagg tactgtgtta tccataatgt tatttagacc ttttagggct
    20461 aacttgggaa atggaatatg gaaacaaact gcagcaaaat cagataactg aaggttttct
    20521 cttttctgat aagcttgcca cgtggtttct aagcaattga gatattgctt ggtagagtaa
    20581 ataccatcaa cataaggtgt gaaactatag ttaggcctcc aaaagtccat aatatcccta
    20641 gtttgagcca cattatcttc atttagagca agaatacgag ggtcagcagt taccaaaata
    20701 gcaatactac cagatccttg agttgattcg ccaggagatc ctacaccgta tctagcaata
    20761 tcactagcaa taacaaggac acgagaatct ggcttagaag ccacatgcag tttagcatag
    20821 tctagagcag cagttgcgct atagcaggct tgttttactt caaaggaacg tgcaaaaggc
    20881 tggataccaa ctaagtgatg tacatagata gctgatgcct ttgactgatc agtactcgat
    20941 tcagttgcca aaataaccat atcaatctta gctcgatctt cgtcagttaa gatttgatct
    21001 gctgcagaag cagctaaagt aataatgtct tcagtgattg gtgccacact aaaagattca
    21061 atgagtagcc cttgactaaa ttttgctgga tccacttggc gtgcaagcgc taaatcttcc
    21121 aatttcaaga catattgact ggttgcaaaa ccaatcttat caattccaat tgtcatattt
    21181 gtccttcttt tagttatttt tatagtctta cccattctat cacattttac tgcaaaatta
    21241 gactgataaa gttatttgtt ttatccttta atagttaaaa tgttcatgac cacatgaagt
    21301 ttttcgaatg tttatttatt ctggtatttt ttggtaaaat tagttagaat agtatgaagt
    21361 atgcttacag aaaggttatt agagatgaca aaagctgacc agatttttaa agctaatatt
    21421 caaaaaatta taaatgaagg atcattgagt gagcaagcac gtcctaaata taaagatggt
    21481 cgaacagctc attctaagta tattactggg gcgtttgctg aatatgattt agctaaagga
    21541 gagtttccca tcacaacttt acgacctatt ccaattaaat ctgctataaa ggaattattt
    21601 tggatatatc aagatcagtc taacagttta gatgtgctag aagctaaata taatgttcat
    21661 tattggaatg aatgggaagt tgaccagaca cgtactattg ggcaacgtta tggtgctgta
    21721 gtcaaaaaac atgatatcat ctcaaaaata ctaaagcaat tagcagaaaa tccttggaat
    21781 cgtcgtaatg tcatttctct ctgggactat gaagcatttg aggagacaaa agggttgttg
    21841 ccatgtgcct ttcaaatcat gtttgatgtt agacgtgtag gggaagatct ttatttagat
    21901 gctagtttga cgcaacgttc taatgacata ttagttgctc atcacatcaa tgccatgcaa
    21961 tacgttgcct tgcagatgat gattgctaaa cattttggat ggaaaatagg taagttcttt
    22021 tattttgtta acaatttaca tatttatgac aaccaatttg atcaggctca agaattacta
    22081 aaacgacagc cagttgccag tcagcctaag cttgttttaa atgttccaga tgggactaat
    22141 ttctttgata ttaaaccaga tgattttgaa ttacaaaatt atgatccagt gaagcctcag
    22201 ttgcactttg accttgctat ttaaacttta tttagatttt ttgtgagcat tttgttcata
    22261 aatttggtaa aataaataga gtttaaaatg aaggaaataa ttaatgacaa aggaaattat
    22321 tgctatttgg gcagaggatg aagcagggct tattggtgtt gcgggtaagt taccatggta
    22381 tttaccaaaa gagttagaac attttaaaaa gacaacgcta catcaagcaa tcttaatggg
    22441 ccgtgtgact tttgaaggaa tgaattgcaa aagacttcct caacgtcaaa cccttgtcat
    22501 gacaagaaat agagattatc aagtagatga ggtgttgaca atgactagta ttgaaaaagt
    22561 cttggagtgg taccatgcgc aggataaaac actttatatc attggtggga ataaggtttt
    22621 agaagcgttt aatggttatt tcgatcgtat cataaaaaca gttatccatc atcgttttaa
    22681 aggagatacc taccgaccaa atctagattt tagtcatttc acgcaagaaa gccaaacgtt
    22741 ctatgctcga gacgctaaaa atccttatga ttttaccgtt actgctttaa aacacaaata
    22801 gtctgaggag atgataagcg atgcaacgta gtatttttgg agtatttacg gcttttttgt
    22861 gcgtgatttg tgttctttgt gccatcccag cttttaaaaa gaatcgttat ggcttagcaa
    22921 gtctgttctt attaaatgcg tttactaatc tggttaatag tattcacgcc ttctatggta
    22981 cattgttttg agatgcgact tgcaaagaca gcactggtga agatttagct atcaagcaag
    23041 aatcaccaaa aaccaataca acacattgac taatattaaa attcagtaaa agataagaga
    23101 aagtaagaga attataagaa atggcaggaa gtagaactaa cgatattaaa gtatactgtt
    23161 cattttgtgg taaaagccag gatgacgtta aaaaaattat cgcaggaaat aatgttttca
    23221 tctgcaatga atgcgtagct ttatcacaag aaattataaa agaagaattg gctgaagaag
    23281 tccttgccga tttgacagaa gttccaaaac caaaagagct ccttgatgtt ttaaatcaat
    23341 atgtggttgg tcaagatcgt gctaaacgtg ctttatcagt tgctgtgtac aatcattata
    23401 agcgtgtctc gtttacagaa agtcgtgatg acgatgatgt ggatttacaa aagtccaaca
    23461 ttttgatgat tggaccaaca ggttcaggaa aaaccttctt agcacaaact ctggctaaaa
    23521 gcctcaatgt accatttgct attgcagatg caacttcttt gactgaagca gggtatgttg
    23581 gagaagatgt ggaaaatatt ttactcaaac tgattcaggc tgctgactat aatgtcgaac
    23641 gagcagagcg tggtattatt tatgttgatg aaatagataa gattgctaaa aaaggtgaga
    23701 acgtatctat cacacgtgat gtatctggtg aaggtgtaca gcaagccctt cttaaaatta
    23761 ttgaaggtac ggtagcaagt gttcccccac aaggtgggcg gaagcaccct aatcaagaaa
    23821 tgatccaaat tgatacaaaa aatatcttgt ttattgttgg cggggctttt gatggcatcg
    23881 aggagattgt taaacaacgt ttaggtgaaa aagttattgg ttttggtcaa aacagccgta
    23941 aaattgatga caatgcttct tatatgcaag aaattatttc agaagatatt caaaagtttg
    24001 ggcttattcc agaatttatt ggccgcttac cagttgtggc agcccttgaa caactaaaca
    24061 catcagattt gattcaaatt ttgacagaac caagaaatgc cctggtcaag caatatcagg
    24121 cccttctttc ttacgatggc gtcgaattgg catttgataa ggaagcctta gaagccattg
    24181 ccaataaagc cattgaacgt aaaacaggag cacgtggtct tcgttctatt attgaagaaa
    24241 cgatgttaga cattatgttt gaaattccaa gccaagaaga tgtcacaaaa gtgcgtatca
    24301 ccaaggctgc tgtcgaaggc aagtcaaaac ccgttttaga gacagcttaa ggagaaataa
    24361 tggctgaaga acaagtctta aatacccata acgcctcaat tttattgagc gctgccaata
    24421 aatctcatta cccccaagat gatttgccag aaattgccct tgctggacgt tcaaatgttg
    24481 gtaaatcaag ttttattaat accatattgg ggcgcaaaaa tttggcaaga acctcaagca
    24541 agccaggaaa aacccaacta ttaaattttt tcaatattga taacaagctt agatttgtgg
    24601 atgtccctgg ttatggctat gccaaggttt ctaaaagtga acgggccaaa tggggaaaga
    24661 tgatcgaaga atacttaacc agcagagaca atctgcgtgc agtcgtgagt ttggttgatt
    24721 tacgtcatgc cccttcaaaa gaagatattc agatgtatga ctttttgaag tactatgaca
    24781 ttcctgttat tgttgtggca accaaagcag ataagattcc tcgtggcaaa tggaacaaac
    24841 atgagtctgt ggtcaagaaa gctttgaatt ttgacaaatc tgatactttt atagtatttt
    24901 cttcggtaga acgtattggt atcgatgatt cttgggatgc tattttagag caggtctagc
    24961 gataggtgtt gatttatcta tgctaaaaca ttctcagtag agggtgtttt tcttatcgaa
    25021 aacataaaaa atcatagtta ggtttaccga ttttacttga cgccttaatg atgacatgct
    25081 agtattttat attaaggaga tgagtcatga cacaagtagc ccaagggcgc tctaaaggaa
    25141 agtcattgtt atgccatcaa tgcaatgccc tttttgtatt tattattttt cttatcttgc
    25201 ttgctgtact ttttggtgtt cgatatcgta atagctctat tgaaggtatc tggcgaacaa
    25261 caagcattga tcagaagtta ggcgatgatt ttgctaaacg tcttactggt ttgcatcaga
    25321 gccctcttat tgatgatagt ttattaacgt catctcagat gatactaaca gttaaaaata
    25381 acaacgttga cttgagtttt agtgttcaag ttgaacgaga catttttgtc aaacgtttag
    25441 ctgcttatca ccaaaatgaa ttattaaaga cattaaagga aaatcattta gttgttggtg
    25501 acttgagtag taaagaacgc caaattattg agaatagtat gccagctagc catgaattag
    25561 aaatgatttt agatcaagct tttgagaaat tagcttctca gatcggaggc aaatataatc
    25621 aaaaaacagg acatttatct gctgttgttc tcaaaggaaa agttaatcgt attttgcaca
    25681 ccattgatat caaagaagaa gtagcagcgg gacatacttc tttttcaaaa ggattactca
    25741 cacctaatgg ttattttgat tacaccagat ttggaaagaa acttgagtta ttaggcgatg
    25801 aaaaaattat ttttaaaaaa gcgctaaaaa aaagtccgtc aagtgtataa cgtagtcaca
    25861 agacggattt tttcatgttt tgaaaattat tcaattgaag aagtttatta ctgatcgttt
    25921 tgcctaatca ctagttgtcc ttcttttagg attgcctgaa gttttttgac ttctggatgg
    25981 tcaagataat aatcagttat acggtcacga atttcctgtt cgataatacg tcgtaatgga
    26041 cgagctccca tagcgtgatt gtaccctaaa tctatcaaat gagctttagc gtcatcagta
    26101 atcgttaaac taataccttt ttttgcggtg gtttgattta cttcagctag cattaaatca
    26161 acaatttctt ctaaactttc tttttgcaga tgattaaatt taatgatact attaaaacgg
    26221 ttcaaaaact ctggtctgaa ataaggtgca atgcgatcca taatgttaga ctcagaagtt
    26281 tccgtatctt gttggccaaa accggcattt gatgtagcaa taataacggt atttttaaag
    26341 ttaatagtat ttccttgtcc atctgtcaat cgtccatcat ctaacacttg tagaagaagt
    26401 gtaataattt gaggatcagc tttttcaatt tcatctagta agacaatagc ataagggtta
    26461 cgacgaacac gctcagttag ggtattatta ttatcatcgt agccaacata accagccgtt
    26521 gtcccaatca attttgacac agcagtgcga tcgttatatt cggacatatc aagtcgaata
    26581 atagcatctt tggaaccaaa taaatcaagt gctaattgtt tagctaactc tgttttacca
    26641 acaccagttg gacccacaaa aaggaaagaa cctattggac gtttaccatc atcaaaacct
    26701 gcccgatttc gtcgaatagc acgtgctact gctgcgacag cctcatcttg tccgatgaca
    26761 tggcttttta agcggctgct aattcctttg agcctttcta aatcattagt ccccatgtta
    26821 gagacaggaa taccagttaa gcgctctaca gactctgcga tatcattgac tgtagcagtg
    26881 acattttggc tttggttatg ttgctcaatt tgcttttgta atgtttcaat ccgtgttttt
    26941 gctgctaaag ctttttcaaa gtcttctttg gcgacagctt tttcttgact ctctttttgt
    27001 ttagctattt cagtttcgag tgtttttaag tcagtgaccg ggtgttgcgc agctaaatga
    27061 gcagctgtca tatccagtaa gtcaattgct ttatctggca ggctacgctg tgggatgtat
    27121 tgaatagaat aatcaacagc agcttttaga acattatcag gaagggtaat atggtggtgt
    27181 tgttcataaa gattacgaat acccattaaa atgtgaaaag tatcttcagc tgatggtgca
    27241 ttcactttaa cttcattaaa gcgacgagca agagcagcat tttttaaaat agtattgcgg
    27301 tattcgtctt gagtagtagc accaatcagt gttaattctc ctcgtgacaa ggctggttta
    27361 agaatatctg caagtccctt tgagcctgaa tcactgcttg tggcaccagc accaactatt
    27421 tgatgaattt catcaaaaaa taagatgata ttcccagctt cttttacttc ttgaatcaag
    27481 ttttgaatgg tctcttcaaa ggaaccacga tactgtgtac cagcttcaag actagaaata
    27541 tcaattgata cgatttcctt gtttttaata gcagctggga catctccatt aacaatggct
    27601 tgagctaaac cttcaatgac tgcagtttta ccgacaccag catctccgac aaggacagga
    27661 ttatttttag ttcgtcgtgc caagatttca gcggtatctt gaatttcttt gttacgacca
    27721 atgacggggt caagatgccc ttgacgagct tcttgtgtta agttagttcc gagttgagtc
    27781 aatacactat cagctttagg tgttaacatt tgagaatttg ttgctttggt tgtcgctaca
    27841 gggagttgtc ctgtttgacg atagtgttgg aattcttcgg gagttatttc gcgaccgtta
    27901 acgagatagc ggggattttc gctacgataa ccacccatgt ttgccattaa ttggttgaaa
    27961 atatcatcca tatttacaaa aggatcttta ccagaaaaat gtgtcatatc agttacctcg
    28021 caataaaaaa tagactataa gatgtttgta agcagtcgca gaatcgttgt taggatttta
    28081 catgatagga aaccctttgc taataaaatg attcagacat tatttttact catcttatag
    28141 tattattata atcaaaaggt cagtaaaggt caaacaaaaa cacttgattt tcaaaaagct
    28201 aaataaacac gaaaagtaag tgcttatatg atgactttag aataaatcat aagttttaaa
    28261 aagatcatcc tattctatag cacttagact gtcaatgaga gaaaaacaaa tgttttcatt
    28321 aacaagttgg cgctttcatg gtataataaa gtgctaagac gcaattctat tataaggggg
    28381 aatcatggaa gcactcaaaa aaattgccgg tgttaccgct gcgcaatatg tgactgatgg
    28441 catgaccatt gggcttggaa ctgggtcaac ggcttactat tttgttgagg aaattggccg
    28501 tcgcgtaaag caagaaggac tgcaagtggt tggtgtgacc acgtcaagtg tgactagcaa
    28561 gcaagcagaa gtcttgggca ttcctttaaa atcgatagat gatattgata gcattgacct
    28621 caccgtagat ggtgctgatg aagtggataa ggatttcaat ggaatcaagg gtggtggcgc
    28681 agccttacta atggaaaaaa ttgttgcaac accaacaaaa gaatacatct gggttgttga
    28741 tgcttctaaa atggtagagc atctgggtgc ctttaaatta ccagtcgaag tcgttcaata
    28801 tggtgctgat cgtttgttcc gtgtctttga aaaagctggt tacaaaccgt cttttcgtat
    28861 gaaaggtgat agtcgtttgg tgacagacat gcaaaactat attattgatc ttgatttggg
    28921 ttgtattaaa gatcctgttg cttttggtca cctgctagat ggaacagttg gtgttgtgga
    28981 acacggtctc tttaatggta tggttgataa ggtgattgtt gctagtaaag acggcgttac
    29041 tgttttagaa gcgcctacag caggctagtc ttagcatata acagcgttaa tatattttat
    29101 aggtattggg gagtcaaccg taacctcccc tagattggag acttatgtca aaatttaatc
    29161 gtattcactt ggttgtttta gactctgtcg gtattggtgc agcatcagat gctgacaaat
    29221 tctttaatgc tggtgtagct gatacagatt ctgacaccct cggtcatatt tcagaagcag
    29281 caggcttatc ggttccaaat atggcaaaaa ttggacttgg aaacatttct cgtccaatac
    29341 cactaaaaac tgttccaaca gaagacaatc ctactggtta cgtgaccaaa ttggaagaag
    29401 tatctcttgg aaaagatacc atgacaggcc attgggaaat tatgggcttg aacattacgg
    29461 aaccttttga cactttctgg aatggtttcc cagaagagat tttaactaag attgaagaat
    29521 tctcaggccg caaaatcatt cgcgaggcca acaaacctta ttcaggaact gcggttattg
    29581 atgattttgg tccgcgtcaa atggaaacag gtgagttgat tgtttacacc tcagcagacc
    29641 cagtgcttca aattgcagcc catgaagaca ttattcctgt ggaagagctt tacaagattt
    29701 gtgaatatgc tcgctccatc acgcttgaac gccctgccct tttaggccgt attattgcgc
    29761 gtccttatgt aggcgaacca ggaaacttta cacgtacggc taaccgtcat gactatgcag
    29821 tgtctccttt ccaagatacc gttttgaaca aactggctga cgcaggtgtc ccaacttatg
    29881 ccgttggtaa gattaatgac atctttaatg gttcaggtat tacaaacgac atgggacata
    29941 ataagtcgaa cagccatggt attgacacgc ttattaagac tcttcaatta cctgagttta
    30001 ctaagggatt ctcctttact aacctcgttg attttgatgc caactttggt catcgtcgtg
    30061 acccagaggg ttatcgcgac tgcttgcatg aatttgacaa tcgcctacct gaaatcatcg
    30121 caaatatgaa agaagacgat ttgcttctca tcactgctga ccatggtaat gacccaacct
    30181 atgcaggcac cgaccacact cgtgaataca ttccattgct tgcctactct gtatccttta
    30241 ctggaaatgg tcttattcca caagggcatt ttgcggatat ttcagcaact gttgcagaaa
    30301 attttggagt tgatacagcc atgattgggg agtcattcct tagtcactta aaataagaaa
    30361 gttagtaatt gataatggaa gaaatcacga tttatcataa tccaaactgt ggcacttcac
    30421 gtaatgttct tgccatgatt cgccatgcag gtattgagcc tactattatt gagtatttgc
    30481 agacgccacc taatcgggag actttaattg agctcttaca atcgatggga atctctgcaa
    30541 gagaactctt gcgaaccaat gttcctgaat ttgaggctta tggattagca aatcaagcag
    30601 tagctgagaa agacattatt aatgccatgt tggcggatcc aattttgatc aatcgtccta
    30661 ttgttgtgac tcgcaaagga gtaaaacttt gccgtccttc tgagacctta ctggatattc
    30721 ttcctgttcc cctgcctagt ccttatatta aagaggatgg cgagagtgtg aaccctattg
    30781 aggtaaaagg agaaaaagat gtcattgatg actaaaatta acgaaacaaa agacttttta
    30841 gttgctaaag gaattgaagc tccagaattt ggattaattc tgggttcagg acttggtgaa
    30901 cttgctgaag aagtagagaa tcctgttgtt attgattatg cagatattcc aaactggggc
    30961 aaatcaacag ttgttggcca tgctggaaaa ttagtctacg gtgatttagc tggccgtaaa
    31021 gtgctcgcct tacagggacg tttccatttt tacgaaggaa atccgcttga agtggtgact
    31081 ttccctgttc gtgtcatgaa agctctggga tgtgaaggcg ttcttgtcac aaatgcagct
    31141 ggtggtatcg gctacgggcc aggtaccttg atggcaatca cagaccatat caatatgacc
    31201 ggaaataacc cactaatcgg tgaaaacttg gacgagtttg gtccacgctt ccctgatatg
    31261 tctgatgcct atactaaggt ttatcgcaat aaggcacatg aagtggctga aaaaatgaac
    31321 atcaaactag aagatggtgt ttatatgggc ttaactggtc caacttatga gacaccagca
    31381 gaaatccgtg ctttcaaagt attaggagca gatgctgtcg gcatgtcaac tgtaccagaa
    31441 gttattgtgg ctgctcattc tggacttaaa gtacttggta tttcagctat tacaaacttt
    31501 gcagctggtt ttcaatcaga attgaaccat gaagaagttg tggaagtgac ccaacatatc
    31561 aaagaagatt tcaaaggtct tgttaaagct attttagcgg agttgtagga cgaacaaaat
    31621 caactggagc attactacag gaatgttatt ttatgtcgtc agtttggcac atctgttcgc
    31681 aataaaaaaa tcaaaaaata atcacggagt gtgagttcca tgaatgttga actcagattc
    31741 tagcttttct aactaacata accaacgaag ggaaagagac gtattcggtt taaattgagt
    31801 atggactcga acatttcttc gtattaattt ttaaataata aaggaaagag agttagtcct
    31861 ttcttatttg aactcgattt ttagctctct tctattcaat atcaattatg aaaggaatgg
    31921 ggttgtattc aattgaatac gggcggaaag ctcggaaact agataaacta acttttgagc
    31981 tcacacatgg cgttagttcc ctaaatttca gtcgctttct gtccgccctc tgaccttcta
    32041 caaaataaaa ggaaaggtag ggctaactgt attcattgaa ttgaatacgg gcggagaact
    32101 gtttttcttc cttataaaaa ataaaaaaat aagaaaggtg agggctgagt tcattaattt
    32161 gaattcgggc taaggacttg gtcaaaaaga taagttgtct agaaaatcag gattttctgc
    32221 caacttccta ttttgccatc gttcttttaa cgccctcagt atcataattt atgtctatcc
    32281 atatttctgc caaaaaaggc gatattgctg ataaaattct tctacctgga gatcctttgc
    32341 gcgcgaaatt tatcgctgaa aatttcctag aagatgcagt gtgttttaac gaagtgcgta
    32401 acatgtttgg ctacacagga acttacaaag ggcaccgcgt ttctgtcatg ggaactggta
    32461 tggggatgcc ttcgatctct atctatgctc gtgaattaat cgttgattac ggtgtcaaaa
    32521 cattgatccg tgttggtact gcgggtgcga ttgacccaga agttcatgtg cgtgaattgg
    32581 tgcttgccca agcagcagca accaactcaa atattatccg taatgacttc ccagaatttg
    32641 atttcccaca aattgctgat tttggtttac ttgacaaggc ttaccatatc gccagagaaa
    32701 tgggagtaac aactcacgtt gggaatgtgc tttcttctga tgtcttttac actaacatgc
    32761 ctgagcgtaa tatggctctt ggtaaattgg gtgttaaagc catcgaaatg gaagcagcag
    32821 ctctttacta tttagctgct cagcaccatg tcaaagccct tggaatcatg acgatctcag
    32881 ataacttgaa tgatccaacc gaagatacta cagctgaaga gcgccaaaca actttcactg
    32941 atatgatgaa ggtcggcttg gaaaccttaa ttgccaatga ctaataatca aacactagac
    33001 atccttttgg atgtctatgc ttataatcac gcctttagaa ttgctaaagc cttgccaaat
    33061 atccctaaaa ctgccctcta tttactagag atgttaaaag agcgcagaga attgaacctt
    33121 gcctttctgg cggaacatgc agcagagaat cggaccattg aagaccagta ccactgttca
    33181 ttatggctta accaatcgct tgaagatgag cagattgcca attacatttt ggatttagaa
    33241 gttaaagtaa aaaacggtgc tattattgat ttcgtcaggt cagtgtcgcc tattctttac
    33301 cgactttttc tcagactaat cacgtcagaa attccaaact tcaaggctta tatttttgat
    33361 acaaagaatg accaatatga tacctggcat tttcaggcca tgttggaatc tgatcacgag
    33421 gtttttaagg cttacctgtc tcaaaagcag tctcgcaatg tgacgaccaa aagcttagca
    33481 gacatgttga cgttgacctc cttacctcaa gaaatcaagg acttggtttt tttgttacga
    33541 cattttgaaa aggctgtccg taatcctctg gctcatttga ttaagccttt tgatgaagag
    33601 gaactgcatc gcaccactca tttttcttct caggcttttt tggaaaacat tatcaccttg
    33661 gcgacttttt ctggtgtaat ctaccgacgt gagccttttt actttgatga catgaatgcc
    33721 attattaaaa aggagttgag cctttggaga caatctattg tctgatattt atcaaaaaac
    33781 acgataactt gaccgataca ggtcttacta ccgtgttttt ttagtatgac gattgaaaaa
    33841 gacattaatc aaaggttact tcttcgagaa ggtattcgat aaaacgttcc cccattttgg
    33901 acaagttggc tttttcatgc ttgataaaaa caatgtcaat ttcgtcaggg acatctagcg
    33961 ggatagccac aatctggtca ccatttagat tgctatttag aataccactg gcaacggtgt
    34021 agccatctaa accaatcatt aagttaaaga gggtggcacg gtcactgacc acaattgatt
    34081 tgttgtgggg catctgggac atcatctctt ctgaaaaata aaaggagttg tgaatccctt
    34141 ggtcatagct caggtaagga aaatctctca agtcgtccat gcttaatagg cttttagttg
    34201 ctagaggatt tgatttgctg acaaaaatat gaggctgtgc cttaaataat ggagaggcag
    34261 tcaaatgatt gtcatcaaat aatttggtca agacatctcg gttatagtcg ttgataaaga
    34321 gaacaccaat ttcagatcga aagtttttga catcatcaat gatttcccaa gttcttgtct
    34381 cgcgcaaaaa gagttcgtac cgagtcatgt cggtccgctt gaggagtgag acaaatgcat
    34441 tgactacgaa ggcataatgt tgagatgaaa cgctaaagag ctctcggcca gtattgtggt
    34501 ttttatagcg gtcttctaac agtgatgttt gctctataat ttggcgagca taagataaaa
    34561 attccacccc atcttttgtc aaggtgatcc ctttaggatt tcggttgaaa atggtaatgc
    34621 ccatctccat ttccaaatcc ttgaccgcat tggatagact tggttgtgtg ataaataatt
    34681 gcttagcagc ttcattcata gagccgcact caacaatttt gataatataa tgcagttgtt
    34741 gaattctcat aagtacagtc tagctcaaaa aaaataaaga cgcaagcaca aacgtcatca
    34801 tgggtttaga actttgaaaa agcgctggag tcttttctcg atatggccta ggataaatat
    34861 gattcaattt tgagagttga atctatcaat ttcattgccc ttttattttt cttgtgttat
    34921 attaatagta ttaacaaata ggtatttttc taatcaaagg gtggtggtcg tgtgaatgtt
    34981 actgaacaaa atagtcatca aatcttaatc caaaagttat tggtcagtat ccactatttg
    35041 actctttttc gagatgaact gaagcttgta gaacgaactc cttctatact tggaggggaa
    35101 tttccagctc atttagtaca gtctgagttg ggagatattg ttgcggccat tgataccttg
    35161 gatatgcagc aacgcttgat tgagtctacc ttttggtatg aagaatcagc ttttaagttg
    35221 atgaacaaaa ctttggatat tgtcgataat tggattaaag gagtggatca tctgatagat
    35281 ttatgccagt ccaaagaagt ctttcaaatt attattggag ataaacgcat tcgagttttt
    35341 ggggtcttaa gtgatgtttt ttcatcttta aaagtgagtg ctttgtcact taaggaagct
    35401 cctattccgg atgtgctcta tgaacatatc cagagggtta atcttgaaga agaaactttt
    35461 ataaaatatt accaaagccc taaggtaccc acaggtgagt ttgaataaat gattgggtaa
    35521 aaatgataaa atgagttgac gtaagtatac aaaaaaagat atagtaggaa aaatgtgttc
    35581 aaataacaaa aagttttgac atcttgtttt aaaaaagcta taatagttta aatttagaca
    35641 cctttaagtg agtccagaga ggcaaacaag gtatacaaga taaaaaaagg gaattccctt
    35701 ttagtttgct gtagcctcgc ttctttggta gcgaggcttt ttggtgctta atgagatatt
    35761 gacacattat agaaaggata agttatgaaa gaagaacgcc caattattgc tttagacttt
    35821 tcatcatttg aggagactaa agcattttta gacttatttc cagcagaaga aaagctatac
    35881 gtgaaaattg gtatggaatt atattatgcg caaggaccag atattgttcg gtctatcaaa
    35941 tcgttagggc ataatgtatt tttggattta aaattacatg atattccaaa tactgttcgt
    36001 gctgctatgg cagttcttaa agaattagat attgatatgg caactgttca tgcagctggt
    36061 ggtgtagaga tgctaaaagc agctcgagaa ggactaggcc aaggccctac cttaattgcg
    36121 gtaacgcagc taacttcaac cagtgaagac caaatgcgtg gtgatcaaaa tattcaaacg
    36181 agtcttttag agtctgtttt gcattacagc aagggggcag ctaaagctca gctagatggg
    36241 gtggtttgtt cggcacaaga agtagaagct atcaaggcgg tgacgcctac gggatttact
    36301 tgcttaactc ctggcattcg tcctaaaggc agtaatattg gcgatcaaaa acgagtgatg
    36361 actccaaacc aagcaagacg cattggaagt gattatattg tggtagggcg accaattacc
    36421 caggcaaaag acccagtggc tgcttaccaa gccataaaag ctgagtgggc aggctaacag
    36481 ataagattag gaaaccaaca cttgtctgtt aaagaagaaa aaggagaata agaaatgaca
    36541 ctagcaagcc aaattgcaac tcaattactt gatattaaag ctgtttattt aaagcctgaa
    36601 gatcctttta cgtgggcatc tggcattaaa tcacctattt acactgataa tcgtgtcacc
    36661 ctttcttatc ctaagactcg tgatttaatt gagaatgggt ttgtggaaac tatcagggct
    36721 catttcccag aagttgaggt catcgctggt acagctacag caggtattcc tcacggtgcc
    36781 attatagcag ataaaatgac tcttcctttt gcttatattc gcagtaagcc aaaagatcat
    36841 ggagcaggca accagattga ggggcgtgtg cttaaaggcc aaaaaatggt tatcattgaa
    36901 gatttgattt caacaggtgg ttcggtacta gatgcagccg cagcagccag tcgtgaggga
    36961 gctgacgttc taggagttgt tgcgattttc acttatgagt taccaaaagc tagtcagaat
    37021 tttaaagaag ctggtatcaa gttgattacg ctttctaatt atactgagct aattgcagtt
    37081 gcaaagttgc aaggctatat tactaatgat ggtttacatt tacttaaaaa atttaaagaa
    37141 gaccaggtaa actggcaaca ataaggaact atcagccagg tttattttta atgaaaaaat
    37201 ctctttaacc ccaattcaaa atgttatgtt ttgattgttt tgtctacatt ccttacacat
    37261 cacattctaa tttctaacct tttaatggtg gttttctttt atttgtgttt taataaaaaa
    37321 gaatgtttta ggattcatat cttagaaagg aagagtagct atgacttatc aagatgcgac
    37381 ggctatggct attgctgttc agaccggtca gaccacacca ctagaattag taacccaggc
    37441 tatttataag gctaaaaagt tgaaccctac cttaaatgct attacctcag aacgctttga
    37501 agcagcccta gaagaagcca aacaaaggga tttttcaggt aagccttttg caggagttcc
    37561 catttttttg aaagatttgg gacaagaatt gaagggagac ttatcaacat cgggttctaa
    37621 gctattcaag aatcatcatg cgactaaaac ggatttattt gtgaaaagat tagaagcttt
    37681 aggctttatt attttagggc gctccaacac gcctgaattt ggctttaaaa atattagcga
    37741 tagcagtttg cacggaccag tgaatttacc aaaggataat acacgaaatg ctggtggctc
    37801 atctggggga gctgctgctc tagtgtcatc aggaattagt gcactagcaa ctgctagtga
    37861 tggtggtggt tctattcgaa ttccagcctc gtttaatggc ttaattgggc tcaaacctag
    37921 ccgtgggcgc atgcctgtcg gacctggttc ttatcgaagc tggcaaggag cctcagttca
    37981 ttttgccttg accaaatccg ttagagatac tagaaatcta ctctactatt tacaaatgga
    38041 acaaatggaa agccccttcc ccctagccac cttaacaaaa gatagtattt atcaatcgct
    38101 acaacgtccc ttgacaattg ctttttatca acggttaagt gacggtagtc cagtatcttt
    38161 agatactgca aaagctttaa aacaagcagt aacttggcta agagaacaag ggcatcagct
    38221 agttgaattg gaagagtttc ctgtagatat gacagaagtg attcgtcatt attatattat
    38281 gaatagtgtg gaaacggctg ctatgtttgc tgatattgaa gacacttttg gacgtccgat
    38341 gaccaaagac gatatggaaa ccatgacctg ggctatttac caatcaggta aagacatccc
    38401 agcttggcgt tactcacagg tccttcaaaa atgggatacg tacagtgcaa ccatggctag
    38461 ttttcatgag acttatgacc tgttgttgac gttcacaacc aacacaccag ctcctaagca
    38521 cggagaactt gtcccagatt cgaaactcat ggctaacttg gctcaagctg aaattttcag
    38581 cagtgaagaa caatttaatt tggtcgaaac catgtttggt aagagtctgg ctattaatcc
    38641 ttacacagct ctgcctaatc taactggcca gccagctatt agtttaccta cttacgaaac
    38701 taaggaaggt ctcccaatgg gcattcaact aattgcagcc aaaggtagag aggacctatt
    38761 attaggaatt gcagagcagt ttgaggcagc aggattattg aagattcctc aataataatc
    38821 ttataaaaca gtttaactat tatagattaa ctttttaaag agattgagcg ctcactgata
    38881 acacaactta atcaaaatgt tatactattc ttatcttaat aaaggagtta ctatgaagaa
    38941 atcagttact ttactgtcta tcggacttgc cagcctttta ttggcagcat gtgcgccaca
    39001 taaatctcaa aaatcaagtt gggacactat taaagacaaa ggggtgttaa aagtagctac
    39061 cccaggaacc tatcagccaa cttcttttta caacgataat aatgagttag taggttacga
    39121 agtagatatg gtcaaagaaa tcggtaaacg acttaacatt aaagtcaagt ttgttgaaac
    39181 aggatttgac caagccttta cctcagttga tagtggtcga gtggatattt ctttgaacaa
    39241 ctttgacatt accccaaaac gtcagaaaaa atacaatatc tctacgcctt ataaatacgg
    39301 ggtaggaggc atgattgtcc gtgctgatgg cagctcaaac atggctaaaa aagatcttag
    39361 cgactggaaa ggaaaaaaag cagccggtgc ttctggaaca gagtacatga aagtagcgca
    39421 aaaacaggga gctgaactgg tgacctacga taatgttaca ggagatgttt atctaaacga
    39481 tgtggctaac ggtcgaacag atttcattcc aaatgactac ccagctcaaa aactatttgt
    39541 agattatatg ctctctcaaa atccaaatct aaatgtcaaa atgagcgatg ttcagtacaa
    39601 cccaaccgaa caaggaattg ttatgaacaa aaaagacgat agcctcaaga aaaaaataga
    39661 tgctgttatt aaagacatga taaaagatgg tagcttgaag aaaatatctg aaacctacta
    39721 tgctggtcaa gatttgacaa aaccttttgg taaagacaag aaaattcccg tcattgatac
    39781 gaaagacgtt aactaatgct tgatgttaaa ggagtcctaa ccacatgatt aatatccagt
    39841 taatgaaaga tagtttagga tttgtgttat cgggattacc ttataccctt ggcatatcgt
    39901 tgcttagctt tttaacgggg ctggtctttg gtttgctcct tgccctacta ggaaggtcac
    39961 gtcagccatt gctacactat cttgttaggg cctacatttc tatcatgcgg ggtgtgccga
    40021 tgattgtggt gctctttgtt ctttatttcg ggttgcctta ttatggttta gaattaccag
    40081 ccttactttg cgcttacctt ggtttttcta tggtcagcgc tgcctacatt tctgaagttt
    40141 ttcgctcttc tatagaagct attgacaagg gacagtggga agcagctaag gctttggggt
    40201 taccatattc tcttatggtt aagaaaatta ttcttcctca agcctttaga attgcagttc
    40261 ctcctctagg caatgtcatt attgatatgg ttaaaagttc gtcgctagct gccatgatta
    40321 ccgtaccaga tatttttcaa aatgccaaaa ttatcggtgg tagggagtgg gactacatgt
    40381 ccatgtacat tttagtagcc tttatctatt ggattattgc ttttttgtta gaacgttacc
    40441 aagaattctt agaaaataag ctagcacttg tttaatatcc tgtaaaaaac gaatattaac
    40501 cctggaaata tcatattttc agggtctttc tatttaaaat gtggtaaact agatagaaaa
    40561 ggacatcgta tttaacttag aaactgacgt gattagaaag gaatcttatg gctcattcaa
    40621 tttggcatga gaaaatcaaa tcatttttgc cggagcatta ctacggtcgc atcaatcact
    40681 ttttagatga agcctatgct tccggtcttg tctaccccca acgagaaaat gtctttaaag
    40741 ccttacaagt cactcctttg gaagaaacca aagtgttgat tttaggacaa gacccttatc
    40801 atggccccaa acaggcccag ggcttatcat tttcagttcc agaagagatt tctgctccgc
    40861 catcccttat taatatttta aaagaattag cagatgacat tggtcctcgt gaccatcatg
    40921 atttaagcac ttgggctagt caaggggttc tgcttttgaa tgcttgctta acagtgccag
    40981 caggccaggc taatgggcat gcaggcttaa tatgggagcc atttacagac gctgttatta
    41041 aagtgctgaa tgagaaagac agccctgtag ttttcatttt gtggggagcc tatgcaagga
    41101 agaaaaaagc cttcattact aatccaaagc accacatcat cgagagccct catccaagcc
    41161 ctttgtcatc ttatcg
//
