LOCUS       NZ_LS483337            21702 bp    DNA     circular CON 13-FEB-2024
DEFINITION  Streptococcus pyogenes strain NCTC12047 chromosome 1, complete
            sequence.
ACCESSION   NZ_LS483337
VERSION     NZ_LS483337.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1
  AUTHORS   Doyle,S.
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUN-2018) WTSI, Pathogen Informatics, Wellcome Trust
            Sanger Institute, CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 01:05:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,789
            CDSs (total)                      :: 1,700
            Genes (coding)                    :: 1,640
            CDSs (with protein)               :: 1,640
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 31 of 60
            Pseudo Genes (internal stop)      :: 23 of 60
            Pseudo Genes (multiple problems)  :: 19 of 60
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:22:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 410056
            Orig. end                         :: 431758
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LS483337.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21702
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..21702
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21702
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:16702]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..16702
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(360..375)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.57"
                     /tool="antismash"
     gene            428..1324
                     /gene="era"
                     /locus_tag="DQL03_RS02250"
                     /old_locus_tag="NCTC12047_00447"
     CDS             428..1324
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="era"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /locus_tag="DQL03_RS02250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00447"
                     /product="GTPase Era"
                     /protein_id="WP_002985743.1"
                     /transl_table=11
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMG
                     IYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMI
                     IERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTLIKL
                     LTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKRDEET
                     DKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVKVKKNW
                     RDKKLDLADFGYNEKEY"
     gene            1345..1821
                     /locus_tag="DQL03_RS02255"
                     /old_locus_tag="NCTC12047_00448"
     CDS             1345..1821
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /locus_tag="DQL03_RS02255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00448"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_111674845.1"
                     /transl_table=11
                     /translation="MPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVLMQLRGDKKTW
                     TIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNIYTHFEEVYPNGDAVQTIVFIYE
                     LTAVSDMTIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
     misc_feature    complement(1372..1388)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.42"
                     /tool="antismash"
     gene            complement(2127..2381)
                     /locus_tag="DQL03_RS02260"
                     /old_locus_tag="NCTC12047_00449"
     CDS             complement(2127..2381)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990779.1"
                     /locus_tag="DQL03_RS02260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00449"
                     /product="hypothetical protein"
                     /protein_id="WP_011106868.1"
                     /transl_table=11
                     /translation="MSGLFYHKSYFFKSEQVYDLLNEIRMRYPHAHIILIGNHINYEEI
                     FKNHYRVFGVIDTTSHKSLRSIRDQIQLYLDELYNSNNG"
     gene            2682..2900
                     /locus_tag="DQL03_RS09320"
     CDS             2682..2900
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016296.4"
                     /locus_tag="DQL03_RS09320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="WP_072135532.1"
                     /transl_table=11
                     /translation="MVLYSTRERIEFYGELSEIVKQEPRLFQCHRSFVVNPYNISSIQR
                     LERKVYLKKRFILSSIKAKSYCSKRSS"
     gene            complement(<3121..4703)
                     /locus_tag="DQL03_RS09325"
                     /pseudo=""
     CDS             complement(<3121..4703)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205155.1"
                     /locus_tag="DQL03_RS09325"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /pseudo=""
                     /sec_met_domain="Peptidase_C39 (E-value: 1.4e-18, bitscore:
                     63.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSCKRTFVPQIDARDCGIAALASIAKFYGSDYSLTHLRELAKTN
                     KEGTTTLGIVKAAKEMGFEKNISSLEIQIPPLK"
     misc_feature    complement(4679..4692)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.72"
                     /tool="antismash"
     gene            5001..5225
                     /locus_tag="DQL03_RS02285"
                     /old_locus_tag="NCTC12047_00453"
     CDS             5001..5225
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994580.1"
                     /locus_tag="DQL03_RS02285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00453"
                     /product="ComC/BlpC family peptide pheromone/bacteriocin"
                     /protein_id="WP_111674847.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 9.4e-13,
                     bitscore: 45.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTTIKQFEIMDEAMLTGIEDGCSWHGLAQAAVFTGAGNGFRLGV
                     KTRTWQGAAAGAAGGLVIGGVGYGATCWW"
     gene            5203..5379
                     /locus_tag="DQL03_RS09185"
                     /old_locus_tag="NCTC12047_00454"
     CDS             5203..5379
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994581.1"
                     /locus_tag="DQL03_RS09185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00454"
                     /product="hypothetical protein"
                     /protein_id="WP_002994581.1"
                     /transl_table=11
                     /translation="MGRLVGGNNHGYQKFFAWFSYWFTLPNFRQYIIEYPEKLEKPIED
                     TKMGLYSVYIGDL"
     misc_feature    5659..5672
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.63"
                     /tool="antismash"
     gene            6070..6198
                     /locus_tag="DQL03_RS09460"
     CDS             6070..6198
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DQL03_RS09460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_002994583.1"
                     /transl_table=11
                     /translation="MTELTSISGGSQKSYCVGLITGRIWKKKLLGQKIVVSDYTFR"
     gene            6596..6823
                     /locus_tag="DQL03_RS02295"
                     /old_locus_tag="NCTC12047_00456"
     CDS             6596..6823
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062179.1"
                     /locus_tag="DQL03_RS02295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00456"
                     /product="Blp family class II bacteriocin"
                     /protein_id="WP_028797129.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.2e-16,
                     bitscore: 57.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKTMEQFEVMNSEMLAGVEGGWGGWGEAIAGLLGGFAPSPTLD
                     QLNGKWPIRKPSKPCSPYGTGGTPNACNGL"
     gene            6872..7189
                     /locus_tag="DQL03_RS02300"
                     /old_locus_tag="NCTC12047_00457"
     CDS             6872..7189
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994587.1"
                     /locus_tag="DQL03_RS02300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00457"
                     /product="hypothetical protein"
                     /protein_id="WP_002994587.1"
                     /transl_table=11
                     /translation="MLTLYKRQIAEVWEIGRETPQPEWVRDAFRKNYICWLDEHVRILM
                     TGLNPSLTTNLKIGATGTVGGGFAGYGMYVLGYPGDFLDVTNHRVISAKKFHKEYQIID
                     G"
     gene            <7372..8393
                     /locus_tag="DQL03_RS09330"
                     /pseudo=""
     CDS             <7372..8393
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558257.1"
                     /locus_tag="DQL03_RS09330"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="QEYEKYGESAFPGHGSALRHAQFEIKKLEKENKLLQEELALLKKF
                     QVFLKPNRK"
     gene            8607..9982
                     /locus_tag="DQL03_RS02320"
                     /pseudo=""
     CDS             8607..9982
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /locus_tag="DQL03_RS02320"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLHKEKPDYNRNQYGFYTLDQLVPDEHFLRQVEAVIDFDFIYDLV
                     GDTYSSDNGRPSLDPVMLVKIPLIQCFYGIRSMRQTIKDIEVNTAYRWFLGLTLDDKVP
                     HFTTYRKNYSRRFQEKGLIESIFTHILGLCINTGLIDPTEIFIDGTHMKAAANNRKFIN
                     REVEKQAKFMSEQLEIEINRDREKHGKKPLEPVAKKISTTDPESGWFHRS"
     misc_feature    complement(10002..10015)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.7"
                     /tool="antismash"
     misc_feature    10033..10051
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.67"
                     /tool="antismash"
     misc_feature    complement(10181..10195)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.84"
                     /tool="antismash"
     gene            10230..10979
                     /locus_tag="DQL03_RS02325"
                     /old_locus_tag="NCTC12047_00462"
     CDS             10230..10979
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528343.1"
                     /locus_tag="DQL03_RS02325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00462"
                     /product="response regulator transcription factor"
                     /protein_id="WP_030126108.1"
                     /transl_table=11
                     /translation="MNIFVLEDDFLHQTRIEKIIYKILTDNKLEVNHLEVYGKPNQLLE
                     DISERGRHQLFFLDIDIKGEDKKGMEIAVEIRNKDPHAVIVFVTTHSEFMPVSFQYQVS
                     ALDFIDKELPEELFSHRIEKAITYVQDNQGKTLAEDSFVFTNVKSQIQVSFSDLLYIET
                     SLIPHKLILYSTKQRVEFYGQLSEIVEQDDRLFQCHRSFVVNPYNISSIDRSERLVYLK
                     GGLSCIVSRLKIRSLIKVVEELHTKEK"
     gene            10980..12314
                     /locus_tag="DQL03_RS02330"
                     /old_locus_tag="NCTC12047_00463"
     CDS             10980..12314
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528344.1"
                     /locus_tag="DQL03_RS02330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00463"
                     /product="GHKL domain-containing protein"
                     /protein_id="WP_063631787.1"
                     /transl_table=11
                     /translation="MIYLINTIVITLNVVVLLLIHARIFGYRMDTKKSLLGILTFYICS
                     LLSTSLSNLLSVGFLGGLLLYPLFFLLYTRYIARRKVNGSLLLFYSLFPIAFWDVIHSF
                     IVYFIVFNISFLKNNYHSNIIIMIFSIVAGTMVLLLIQAFNYDFSHLRKKKLNQRTRTI
                     ISIANFSMILYFITIPMIDFIEEVENINFTHYQEMITAIYFLLFICFVNLLDRNLRQEL
                     QKQVVLQKELQLQNMARYSKQIEGLYQNIRSFRHDYANILTSLKIGIDCKDIEMISSIY
                     HKVLKDSGKVLRGEKFNLARLRNINDLPLKSLLFVKLSEAQRLSIPVSIEIGEPISIKN
                     IELIDFLTLVSILIDNAIEGAAESGIVLCFFEQFGKQILIVQNDTFEKQINLSTIFERG
                     VSSKGNNRGVGLSNVREILESYPTVTLKTVSNHFVFKQILEIEIL"
     gene            complement(12462..12587)
                     /locus_tag="DQL03_RS02335"
                     /old_locus_tag="NCTC12047_00464"
     CDS             complement(12462..12587)
                     /GO_function="GO:0005186 - pheromone activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017462.1"
                     /locus_tag="DQL03_RS02335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00464"
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="WP_011017462.1"
                     /transl_table=11
                     /translation="MNNKKTKNNFSTLSESELLKVIGGDIFKLVIDHISMKARKK"
     misc_feature    12647..12663
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.7"
                     /tool="antismash"
     gene            complement(12664..14028)
                     /locus_tag="DQL03_RS02340"
                     /old_locus_tag="NCTC12047_00465"
     CDS             complement(12664..14028)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /locus_tag="DQL03_RS02340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00465"
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="WP_111674849.1"
                     /transl_table=11
                     /translation="MNPNLFKSAEFYHRRHHNFATFLILPSVLLVSFLVIFALFAKKEI
                     TITSQGELTPTKVIASVQSTSDHTIVVNNLKNNKFIKKGDVIIQYSKTMENSQKKALEK
                     QLATLNKQKNGLQILRTSLEQETNLFKGEDEFGYSDTFNHFLEQTQDIIIGIAKKNAEI
                     NNQASLANHAISVITSQLDELHQKITDYEELKQAINNQEYKLSPENPHQTALKKYQTQF
                     QAQEDNSALKEEYLSQIPQNISELESSMANLSIQRASTGNFSLPDTSHRIKIDILKTQF
                     LQNASQQLTTVENQITELKNQIEQANIQLKNNIIIAPETGTIHLNSEFEGKSLIPNGSE
                     VAQIYPDIQKIKEVFITYYVTSEHVSLLKEKQGVRLSLEKVGNQTLTINGTIQTIDKSA
                     TKTNQGNLFKVTALSKLSNKDSDVVQYGLQGRVTSVITRKSYFNYYKDKILNSFN"
     gene            complement(14039..16192)
                     /locus_tag="DQL03_RS02345"
                     /old_locus_tag="NCTC12047_00466"
     CDS             complement(14039..16192)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062135.1"
                     /locus_tag="DQL03_RS02345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00466"
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="WP_111674850.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.6e-44, bitscore:
                     145.9, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1120.7,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISYRKTFVAQTDARDCGVAALASIAKYYGSDYSLAHLRELAKTN
                     KEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDVPYPFIVHVNKEGKFQHYYVVYQNK
                     KNYLIIGDPDPTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPLIFK
                     QRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILKQMM
                     SFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALAS
                     TILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIVIIFIFMHPFEKMNNDVMQSN
                     SMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQ
                     LILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRL
                     NEVYLVDSEFQEAGTLVNQELLHGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVG
                     ISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHINYLPQQAYIFNGSILE
                     NLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARAL
                     LTKAPVLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGK
                     IIEIGSHQELMTKQGFYHHLFSS"
     gene            16475..16702
                     /locus_tag="DQL03_RS02350"
                     /old_locus_tag="NCTC12047_00467"
     CDS             16475..16702
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016754.1"
                     /locus_tag="DQL03_RS02350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00467"
                     /product="Blp family class II bacteriocin"
                     /protein_id="WP_002992018.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.3e-17,
                     bitscore: 58.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKKLETFHQMTIEKLAKVEGGKNNWQANVSGVIAAGSAGAAIG
                     FPVCGVACGYIGAKTAITLWAGVTGATGGF"
     gene            16715..16915
                     /locus_tag="DQL03_RS02355"
                     /old_locus_tag="NCTC12047_00468"
     CDS             16715..16915
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /locus_tag="DQL03_RS02355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00468"
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="WP_002990771.1"
                     /transl_table=11
                     /translation="MTTMKELTINDMASISGGNAPGDAVIGGLGGLASGLKFCKLLHPV
                     LAGGCVVGFTVGGAYLGYTAN"
     gene            17232..17396
                     /locus_tag="DQL03_RS09525"
     CDS             17232..17396
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073350.1"
                     /locus_tag="DQL03_RS09525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bacteriocin"
                     /protein_id="WP_309543637.1"
                     /transl_table=11
                     /translation="MAIINGGGKDGANIFLTGMAGAEQGVTVCAQTGVFIPWQGYILCG
                     AAGAATNII"
     gene            17455..17735
                     /locus_tag="DQL03_RS09530"
                     /old_locus_tag="NCTC12047_00470"
                     /pseudo=""
     CDS             17455..17735
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528350.1"
                     /locus_tag="DQL03_RS09530"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00470"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKILDIIFNLSDRKMIFLENVEKLGGYIVPFTLIILSVAYNFRHP
                     YPIWAAVLGGISLIVIFIYFILIVYLYLRYRYLV"
     gene            17929..18330
                     /locus_tag="DQL03_RS02375"
                     /old_locus_tag="NCTC12047_00471"
     CDS             17929..18330
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771275.1"
                     /locus_tag="DQL03_RS02375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00471"
                     /product="hypothetical protein"
                     /protein_id="WP_023605036.1"
                     /transl_table=11
                     /translation="MRNILRFLGIVIISAVILFSIGSFYDLPLMKNIQLICWSFILDLF
                     VFVYKQRQTTEVLTWYQVVKQFWLFIKCTILIPTLIAFIIIIGCLTSISEVSIYFYLHL
                     IVVCYTIGMILSLGRLISPNHSIFNKLKK"
     gene            18581..19651
                     /locus_tag="DQL03_RS02380"
                     /old_locus_tag="NCTC12047_00472"
     CDS             18581..19651
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528351.1"
                     /locus_tag="DQL03_RS02380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00472"
                     /product="hypothetical protein"
                     /protein_id="WP_063628997.1"
                     /transl_table=11
                     /translation="MMMLRDVKVKMSSLLVGCAATLLVSLSSTVAADSVHSSDRRFGVG
                     YKEETTSQFSSDQPSQVVLYRGEANTVRFTYTNQMSLMKDIRIALDGSDKSLTAQIVPG
                     MGHVYEGFQTSARGIFTMSGVPESTVPVANPNVQTKYTRYFKVIDDMHNTMYKGTVFLV
                     QPQAWKYTMKSVDQLPVDDLNHIGVAGIERMTTLIKNAGALLTTGGSGAFPDNIKVSIN
                     PKGRQATITYGDGSTDIIPPAVLWKKGSVKEPTEADQSVGTPTPGIPGKFKRDQSLNEH
                     EAMVNVEPLSHVVKDNIKVIDEKSTGRFEPFRPNEDEKEKPASDVKVRPAEVGSWLEPA
                     TALPSVEMSAEDRLKS"
     gene            19744..20142
                     /locus_tag="DQL03_RS02385"
                     /old_locus_tag="NCTC12047_00473"
     CDS             19744..20142
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635342.1"
                     /locus_tag="DQL03_RS02385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00473"
                     /product="hypothetical protein"
                     /protein_id="WP_032464238.1"
                     /transl_table=11
                     /translation="MHRLPNRLIPEEDNNKLSRVAKEVVTEPRLNNPFLLPKKVLSLED
                     DAAILNHLEEDRNVNKLFLEPVAAEAKREINFHPSDQQVTAKVKESSDFHQKQHQTGIT
                     YGDDTLADLAHHLLHSDGVIPSLNDKSA"
     gene            complement(20490..20759)
                     /gene="stcA"
                     /locus_tag="DQL03_RS02390"
                     /old_locus_tag="NCTC12047_00474"
     CDS             complement(20490..20759)
                     /codon_start=1
                     /gene="stcA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560518.1"
                     /locus_tag="DQL03_RS02390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NCTC12047_00474"
                     /product="quorum-sensing system protein StcA"
                     /protein_id="WP_023605037.1"
                     /transl_table=11
                     /translation="MTKKQFYLILAISILCFILAVSPKPPIPKHTIERKRTAMTIGHSK
                     QNPHKKEALKHKKNKNKALFLPSGDSAIKSVISMTVRLLLDDQS"
     gene            complement(21281..21523)
                     /locus_tag="DQL03_RS09535"
     CDS             complement(21281..21523)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285423.1"
                     /locus_tag="DQL03_RS09535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_030126784.1"
                     /transl_table=11
                     /translation="MKQQGHTVMMCLNKTLTIKLSAPLTSNDLVPLSTNEVIIMEPLLH
                     LLPKVVPVLIHLVDKANVSWLTMILQLPILLKTIW"
ORIGIN
        1 aggaagaacg caatctcaga agccaccttt tgtctgcctg tttagcttgt gttgctggtt
       61 tattttttag catttcagcc atcgaatggt tatttttact tctagccatt tttttggtca
      121 ttaccttaga aattgtcaat tctgctattg aaaatgtagt tgatttggct agtgactatc
      181 acttttctat gctagctaaa aatgccaagg atatggcagc aggtgctgtt ttgatgattt
      241 ctggctatgc tgtcttgaca ggacttatta tttttattcc taaaatttgg aatattttcg
      301 ttcattaaaa agaaaggaat gggctatcct atgtgatgat ggcataggag aataaggaaa
      361 ggacaagacg gttaagctta gtgacaagct tgatctgaag ccctaccgtt aaagcccgta
      421 attatctatg tttaaatcag gctttgtagc cattcttggt cgtccaaatg ttggcaaatc
      481 caccttttta aatcacgtca tggggcaaaa aattgccatc atgagtgaca aggctcagac
      541 cacccgtaat aaaattatgg gcatttacac cacagaaaca gaacaaattg tctttattga
      601 tacgccaggt attcataaac caaagaccgc ccttggtgat tttatggttg aatctgctta
      661 tagtacttta cgtgaagttg agacggttct tttcatggtt cctgccgatg aaaagcgtgg
      721 taagggtgac gacatgatta tcgagcggct aaaagcagct aagattcccg ttattttagt
      781 catcaacaaa attgataagg ttcatccaga ccaacttttg gaacagattg atgacttccg
      841 tagccaaatg gattttaaag aagtggtccc aatttctgcc ctagaaggta ataatgtgcc
      901 aaccctaatc aagttattaa ctgataatct tgaagaaggt ttccaatatt ttccagaaga
      961 tcagattact gatcatccag aacgtttcct tgtgtcagaa atggttcgtg agaaggtact
     1021 gcatttgacg caacaagagg ttccacattc cgtagctgtt gttgtcgaat ccatgaagcg
     1081 agatgaagag actgataaag tgcatatccg tgcaaccatt atggtggagc gcgatagcca
     1141 aaaaggcatc atcattggaa aacaaggagc catgctcaaa aaaatcggaa aaatggcgcg
     1201 ccgtgatatt gaactcatgc taggtgacaa ggtctactta gaaacgtggg tcaaagtcaa
     1261 gaaaaactgg cgggataaaa agcttgacct tgctgacttt ggttataatg agaaagaata
     1321 ctaacatagt aaagcgagca tcatatgcca caagactaca tttcttatat ccgctccaaa
     1381 gttgggcatg ataagattat tcttaacttt gctggtggga ttttgaccaa tgatgacggc
     1441 aaggtgctga tgcagttgcg tggtgataag aaaacctgga ctattcctgg tggcactatg
     1501 gaactgggtg agagctcttt agagacttgt aaacgtgagt tcttagagga aaccggaatt
     1561 gaggttgaag ctgttcgctt actgaatatt tacactcatt ttgaggaagt ttatcccaac
     1621 ggtgatgctg ttcagaccat tgtctttatc tatgaactaa cggctgtttc tgacatgact
     1681 attgataact ttcataatga ggaaacgctc aagttacagt ttttctctca tgaggagata
     1741 gcagagttag agagtgtctc agccaaacat cgcctgatgt tagaggaata ttttagtgat
     1801 agctttgcta tggggcatta agaactctct aggacagttg gagtattttt ggagattggc
     1861 ttgttaaaaa aatttttgaa agacgatgtt tcgagagctt atgctctctt tttttgcttc
     1921 caatttttct gattaagtct gaataatttt gttaaatgtt aacaggattt tctttccaat
     1981 tgatactagc agatatcaaa catttgtttt agagttatga cgaattgcca cctagccatg
     2041 catgacttag gcaagttgaa cctaactgtg gcaatagact tggaaggggt gacaagaatc
     2101 atttcctaaa agaattgatg aagtgcctat ccattattcg aattgtaaag ttcgtctaag
     2161 taaagttgaa tttggtctcg aatggacctt aatgatttat gacttgttgt gtcaataaca
     2221 ccaaaaactc gataatgatt tttaaatatt tcctcgtaat taatatgatt tccgattaga
     2281 ataatatgag catgaggata acgcatacgt atttcgttta gaaggtcata tacttgctca
     2341 gatttaaaaa agtatgattt atgataaaat aaacctgaca tttgtattta taatctaagt
     2401 ttttcccact aataatttga gtttttagaa agtatctctt gaggtaatag ttaatataga
     2461 tagatatcat atatcctaaa agagaacgat gtaagacttg aataactatc ataattttct
     2521 ccacgtattg aacaatcaat tgactatgtc catcatcaac aaggtcaaac gttagctgaa
     2581 gactccttta tttttaaaga tgccaagact caggttcaga ttccattcag attccatttg
     2641 cagacttact ttatattgaa acgtcatata ttgctcataa attggttctt tattctacta
     2701 gagaaaggat tgaattttat ggggagttat ctgaaatcgt taagcaagaa ccaagattat
     2761 ttcaatgcca tcgatcattt gttgttaatc cctacaatat atcttcaata caacgattag
     2821 aacgtaaggt ttatttaaaa aaacggttca tcttgtctag tatcaaggct aaaagttact
     2881 gctctaaaag aagcagttga aaatctacat aataaggaga cttagatgag tagcatcttc
     2941 tttctagaac ttacttttac tcatgtcatt attttgataa ttttacatgc taaagtatat
     3001 gtatataaag taaccgtgaa aaatctttcg ctttatacgc ttttcttttt ttatattctg
     3061 cccagtttgg aaataggtat cgaatttcaa gatatgaata tcgtttctga tatttatcag
     3121 aatgtcctct tgactagtgg agtgattggc acctagggtt aagttttcta agatagatcc
     3181 actaaagata tgagcttgtt gggggagata gttgatatgc tgacgaagca cttttttatc
     3241 aatcatttta agattttgat gattaataga aatctgtccc ttgtaaggtt caaagaaatt
     3301 aacaatcatt ttagctaatg ttgtcttgcc agaaccacta ataccaacta tactgacttt
     3361 ttcaccctcc ttaatggtca aactgatatc agataaggta tcacgaccaa agccgtattt
     3421 ataagacaag tctgcaaatt ggatatctcc atatagacaa taggtatctg ttaatgcctg
     3481 ttctttttgg aactcagatt taaccaggta aacttcattg agacgattat tagctacctt
     3541 agcggattgc agtttagttt gaagattaat gatattttac cattcataac tagtcgtgca
     3601 cccacccata agatagtaac gtttaaaatg agttgtgctc cttgctttag actactttgt
     3661 agaatactta cttaacttaa aagatttatc caaatagtct acaaattcac tatcgatttt
     3721 ctgataacga atttcctcgc tagtcaatga tttgattgtt tcaataccat taatatcttc
     3781 gataatagca gagctggcca tggaattact ctgcatgaca ttgttattca tcttttcaaa
     3841 aggtttcata aaagtaaaaa tgatgataat gtagattggg atagaaatta atgatagaag
     3901 aaataggtta gtgttttgta cgagtaacac accacctaca atacttaaaa tagagacatc
     3961 taaaaataga gatagaattg tagaagcaag tgcatcaata atagcattag catctgtaaa
     4021 acgtgagatg atttctcctg tccgacgtgt tacaaagaaa gacatgggaa gctcaaaaat
     4081 atgacgaata taggataaaa taacatcaat gcttaatcgc tgactcagta cagtcaggag
     4141 ataatctcgc gaaaaactca tcatctgttg taggatatag gtaacgataa gtccaattga
     4201 gattataccg agtgttggct tcatctgatt tggaatatat tcatcccaaa taccttgtag
     4261 atagtaggaa ccaccaatat ttatcagggt aactaagagg ctcgctaaaa cgatatagaa
     4321 gattaaggac tcttgtttaa aaattagagg tagaaaactc attaagccat tctttttatc
     4381 cttgtgaggt ttatagccag gttcaggtgc taaaaagata gcaacccctg tctattcagg
     4441 agcaaatttt tctttgctca ttttggttac tttaacggag ggatctggat ctccaatgat
     4501 gaaatgttct tttcaaagcc catctccttg gccgctttta cgattccaag ggttgttgtt
     4561 ccttctttat tagtctttgc caattctctc agatgtgtca aagagtagtc agacccgtag
     4621 aattttgcaa tcgaagctag agcagcaatt ccacaatctc ttgcatcaat ttgtggtaca
     4681 aacgtacgtt tacatgatgt cattaatata tttccttcca gtaaattaca aattcattat
     4741 tgcaaaacta ctgataagaa attcgaaaat tcttaaatgg tatctagtat atcctgaatg
     4801 gtattttaaa attaaaagta ataagtttct agtgattatt ttctaattcg aaacgattaa
     4861 aaaactatga aaaaaatcat ttcatgatga aaaaagaaca tttgaagatt ttacggggca
     4921 cagatttctt acgatgctat actgaacatg tcaaggttgc aacaagacat aataaaaaat
     4981 tatataagga gatattcgtt atgaatacaa caattaaaca atttgaaatt atggatgagg
     5041 ccatgcttac tggtattgaa gatggttgtt catggcatgg gttagctcag gcagctgttt
     5101 ttactggtgc tggaaatgga tttagattag gtgttaaaac aaggacttgg caaggagctg
     5161 cagctggagc agctggtgga ctggtcattg gaggagtcgg ttatggggcg acttgttggt
     5221 ggtaataacc atggatatca aaagtttttt gcttggttta gttattggtt tactttgccc
     5281 aattttcgac aatatattat tgaatatcct gaaaaattgg aaaaaccgat agaagacact
     5341 aagatggggc tttactcagt ttatataggt gatctttaag gatttaacat agcttggatg
     5401 tgataggtct cgttggaata agaaaaagta tactggtaaa tgttaaaaaa taggagcaaa
     5461 tagaatgagt ggtgtcttta agaagtgtct tacctttatt atgtcaatta tattctctat
     5521 atttatgact atttttgttc aaactccagt tgttgcgaca tttaacaatg aacggattaa
     5581 tcttaggcaa gggatcaatg gagacttttt aagagtaata atttgcatta tttttataat
     5641 actttgcttt tattttctgt cactcttagc gaaatgtctt atcagccagt aaagttcata
     5701 ttattttttt ttacgactgt agtttctcaa ccaatcttgg aggagattct atttcgagga
     5761 atactgcaag aaaagttatc acgcgtttcg ttttggttaa gcatcattgt gacatctgta
     5821 atattctcgt atattcatgg aaatgacact atattgaata ctcaattcat cagttctttg
     5881 atatatggaa tggcttatca aacaagtaag gatttaagat ttcctattat taaccattct
     5941 ctgcagaatt taatagtact tcttacagtt gttttgctaa agtaagtagt gagaattaat
     6001 aaaaataact gggataatta tagtaatgaa aagattttga caatgacaaa ataatttagt
     6061 gaaataaata tgactgagct aacaagtatt tcaggtggct cccaaaaaag ttattgtgtt
     6121 ggtttgatta caggacgcat ctggaagaag aagcttcttg ggcaaaaaat tgtagtttca
     6181 gattacactt tccgttaatg ttattaaaga tgcgggtgac tatgttgtcg gatttgtagc
     6241 ttcgttagta taataagcat tttatgtcaa agctaagcta tgtatactga ccttgctttc
     6301 tagggaatag gagagagaac ttagaggcat ttcgctggct ttgcattttg tttatgacta
     6361 tatcttaaac ggacatcgaa acatcttgaa tggtagagtg agtcttggac tcatggatat
     6421 aaaattaaga taatatgggt gtttttgaaa ttatgaatgt taaaaagact tcccatttag
     6481 gaaagttaaa tgactgttta ggaaatagtg caggattttt ttaagaagcg ctatactgaa
     6541 tatgtcaagg ttgcaactgg acaaaatata aaaattatat aaggagatat tcatgatgaa
     6601 tacgaaaaca atggaacaat ttgaagtgat gaactctgaa atgcttgctg gtgttgaagg
     6661 aggctggggc ggttggggag aagcaattgc cggtctatta ggaggctttg ctccttcacc
     6721 aacattagat caattaaatg gcaaatggcc aattagaaaa ccttccaaac cttgtagtcc
     6781 ttacggaact ggtgggacac ctaatgcgtg taatggttta taaattagga catatttaag
     6841 tgattatgca ttaaaggaag tggaggtaga tatgctgact ctatacaaaa gacaaatcgc
     6901 agaagtttgg gagattggga gagaaacgcc tcagccagag tgggtacgtg atgcttttcg
     6961 caagaattac atctgttggt tggatgagca tgttcgtatt ctcatgactg gactaaatcc
     7021 ttcgctgaca acaaatttaa agattggtgc aacaggaaca gtaggtggag gatttgctgg
     7081 atatggtatg tatgtccttg gttatccagg tgatttcttg gatgtgacca accatcgagt
     7141 tatttctgcc aaaaaattcc ataaagaata tcagattatt gatggataga aaaagtagac
     7201 tatgaacttt tatgactggt ttaattttga gggtttacaa caaaaaggag ctctttggaa
     7261 gattgtagga agtattttct ttgtcggttt tcatttattc atcatctatt tggtacaaag
     7321 ataattagtt caactttaaa aattcatcct aatagtcttt atcaatggat tcaagaatat
     7381 gaaaaatatg gagaaagtgc gttcccagga catgggagcg cacttcgtca tgctcaattt
     7441 gagataaaaa aacttgaaaa agagaacaaa ctgctacagg aggaattagc tcttctaaaa
     7501 aagttccagg tctttttgaa gccaaaccgg aaataaaatt tcagtttctg aaggaaaata
     7561 gtgttagctt gaatagtcat cacacctgtc aaactcttca agtctcccgt tcaggtttct
     7621 atgcttattt aaaacgtcgt ctatcttcaa agcatgttga gaatgaagct ttgaaggaaa
     7681 tgattaaagc cattttctat gaacataaag agcgttacgg aagtgtacga attacccaag
     7741 aactttgtag acgtggcatc catgtcaatc ataaacgtgt tggtagactc cttcatcagc
     7801 taggtctcta tgctaaagga agtcgatatc aatataaata ctataaccgt cgacgttctt
     7861 cattaactcg tcccaatctt gttaatcaat gtttccaagc gactggtaag aataaattat
     7921 ggctaggaga cttaacctac attcctacac aagaaggaat actttatgtg tctgtcttga
     7981 tagatgttta tagtagaaag gttgttggtt gggcaatggg ccgacgtatg caagacaagt
     8041 tggtaacaga agctttcaaa caagcttata atagagaaaa gcctaaagaa gggggaatcg
     8101 tccatacaga tcagggttct caatataccg gagcatgatt tcaggaccta cttagatgga
     8161 aaaaatgtaa gtccaggatg agtcgaaaag gtaatccata cgataatgca ctcatggaag
     8221 ccttttataa aacattaaaa agagagcttg tcaatgatgc tcatttcgca actattgagc
     8281 aagctcagct tgagattttt aaatatagtg agacttacta taaccctaaa cgtctgcatt
     8341 cagctttaag gtatctctca cctgtagaat ttgaaaaaat agttactcat tagcttaact
     8401 ttatgtctat tttttcttga caagtccaac attcagcaag tgtctttaga tgctgctggt
     8461 tttcaatgcc ttacaggagg tgtacaagcc acccgttttc acgggtgctt tcagactgaa
     8521 gacaaagtcc ttagaatcgc ttttctaggg gctttttatg atatttagga gtataatata
     8581 agaaaaagga cttgtgaggt tctcctatgt tacacaaaga aaaacctgat tataaccgca
     8641 atcagtacgg tttctatacc cttgaccagt tagtgcctga tgaacatttc ctgcgccaag
     8701 tggaagctgt gattgacttc gacttcatct atgacctagt aggagacacc tattcgtctg
     8761 ataatggtcg ccctagcctt gatcctgtca tgttggttaa aatccctctg attcagtgct
     8821 tttatggcat tcgttccatg cgtcagacca tcaaggatat tgaagtgaat actgcctatc
     8881 gctggttttt aggtttgact ttggatgaca aggtgccaca tttcacaacc tatcgcaaaa
     8941 attattcccg tcgctttcaa gaaaaaggct tgattgagtc catttttacg catattcttg
     9001 ggctatgtat caatacaggc ctgattgacc cgacggagat tttcatagat gggactcata
     9061 tgaaggctgc ggctaataat cgcaagttca tcaaccgaga ggtggaaaaa caagccaagt
     9121 tcatgagtga acagctagaa attgaaatca atcgggatag ggagaagcat ggaaaaaagc
     9181 cgctagagcc cgtcgctaag aaaatctcca caaccgatcc agaaagtggc tggtttcaca
     9241 gatcataagg aagtcttcgc ttattctgct caggtggctt gtgacaagta tggatgggcg
     9301 cttgcttata gtgttgaggt tggaaatatc catgatagtc aggcttttcc tgcacttttt
     9361 gccaagcttg aacccttgaa accacagttt attattgcgg attccggcta taacattccc
     9421 agcattgcca agtttctgat tgataaggag atcactcctg tccttcctta cacacgacca
     9481 agaggaaaga aagaccttct acgtccgaaa gaattgattt atgatgagca ctttgattgt
     9541 atcatctgcc ctgaacatca agccttgatc taccgcacta cgaccagaga aggctaccga
     9601 gaatacaaaa gtgaccctgc aatttgtgcc aattgtcccc tgttatctgt atgtacgacc
     9661 agtaagaacc accaaaaagt tgtcacacgg catatttgga aagactattt ggcacagcca
     9721 aggaatacca caatctccgc tatacgagag agaaaggcaa gtccaaaatg gaagataagg
     9781 ttggactgac tttggcatgc ttaaatctca aaaaactggt caaaaggatg gcgggagagc
     9841 ctttttattt tgttcagatg aggtggttta agcacggaaa cagccatttt tatctaaaaa
     9901 cactaaaaaa gacaaacacc aaatcgatgt ttgtcttcaa tctgaagcca cccgttttca
     9961 cgggtggttt ttatttatat aaagctatca gataaaagta gtttttttga aaaaaacatt
    10021 tcattgaatg gttaattgta tatattgtac agcatacaat tgcagcaatg aatagtgatt
    10081 aatgttaaat ggatttaagt atcttataat tatagattcc ttagtgatat gtaaaaaaat
    10141 taatttttat gataaaatag gtgatagttc tattacacta aattttttga aaaagttttt
    10201 ataaatagta agggaaaata aaggttaaaa tgaatatttt tgtcttagag gacgattttt
    10261 tacatcaaac cagaattgaa aaaattattt ataagatttt gactgataat aagttggagg
    10321 ttaaccactt ggaagtttat ggtaaaccca atcagctgct tgaagatata tcagagagag
    10381 gaagacatca gctttttttt cttgacattg acattaaggg agaagataaa aaaggaatgg
    10441 aaattgctgt ggagattaga aataaagatc cgcacgcagt gatagttttt gtgaccacac
    10501 attcagaatt tatgccggta tcttttcaat accaggtttc agctttagac tttattgaca
    10561 aagagttgcc agaggagtta tttagtcatc gcattgaaaa agctataact tatgtacaag
    10621 ataaccaagg aaaaacgtta gcggaggatt catttgtttt tactaatgta aagtcccaga
    10681 tacaagtctc cttttcagat ttgctgtata ttgaaacctc actaattccc cataaactca
    10741 ttctctattc tactaaacaa agagtagaat tttatggcca attatcagaa attgttgagc
    10801 aagatgatcg attatttcaa tgtcatcgtt cctttgttgt caatccctat aatatatcat
    10861 caatagatag atccgaacgg ttagtttatt taaagggggg attatcttgt attgtttcga
    10921 gattgaaaat acgatcatta ataaaagtag tagaagagtt gcacactaag gagaaatagt
    10981 tgatatattt aattaatacg atagtcataa cacttaatgt ggttgtgcta ttgttaattc
    11041 atgcgagaat atttggctat cgtatggaca caaaaaagag cttattaggg attttaacat
    11101 tttatatctg ttctctttta tctacttctt tatccaacct actatcagtg ggttttttag
    11161 gaggactatt actttatcca ttattttttt tgttatacac tcgttatatt gcaagacgaa
    11221 aggtcaatgg ttcacttctt ttattttata gtttgtttcc tattgctttt tgggatgtaa
    11281 ttcatagttt tattgtttac tttattgttt ttaatatttc ttttctaaaa aataactacc
    11341 attcaaatat cattattatg attttttcta ttgttgctgg tactatggtt ttgctgctga
    11401 ttcaagcttt taattatgac tttagtcatt taagaaaaaa gaaactaaat caacgtacta
    11461 gaacgattat atctattgcc aactttagca tgatattgta ctttattacc attccaatga
    11521 tagattttat cgaagaagtt gaaaatatta attttacgca ctatcaagag atgataacag
    11581 caatttattt tcttttattt atttgttttg taaatttatt ggatcggaac ttacgccaag
    11641 aattacaaaa gcaagttgtt ctacaaaaag agttacaatt acagaatatg gctcgctata
    11701 gtaagcaaat cgaaggactg tatcaaaata tcagaagttt tagacatgat tatgcaaata
    11761 ttttaacaag cttgaaaata ggcattgatt gcaaagatat tgaaatgatt tcaagcattt
    11821 atcataaggt gttgaaagat tcagggaagg ttttaagggg agaaaaattc aatctagcaa
    11881 ggctgagaaa tataaacgac cttcctctga aaagtttact gtttgtaaaa ttatcagaag
    11941 ctcaacgctt atccatacct gtatctatag aaattgggga accgatttct ataaaaaaca
    12001 ttgagttaat cgatttttta acccttgttt ctatcttgat agataatgca atcgaaggtg
    12061 cagcagagtc ggggatagtt ctttgttttt ttgaacaatt tggtaaacag atattaattg
    12121 ttcaaaatga tacttttgaa aaacagatta atctttccac gatttttgag cgaggtgttt
    12181 cttcaaaagg aaataatagg ggagttggtt tatcaaatgt tagggagata ttagaatcat
    12241 atcccactgt taccctcaaa acagtaagta atcattttgt ttttaaacag attctagaaa
    12301 tagaaatcct ataatgtaat acttttcttt tttatcacta aaataaaata tttataaaag
    12361 cttccaaggg tctgtagtag gctaaacctg ctaaagactc ttggaagctt ttatgaatga
    12421 tgaattacta gtttatattt taaaattatt ttagaaggaa cttacttttt tctcgctttc
    12481 atactaatat gatctatgac aagtttaaaa atatctccac caatcacttt aagtaattca
    12541 gattcagata atgttgaaaa gttatttttt gtttttttat tgttcattgt aatatctcct
    12601 aataaaatta tatgaaattt tagtttttaa taatttctgg aataaattgg aattttatta
    12661 tatttaatta aaactgttga gtatcttatc tttatagtaa ttgaaatagc ttttccgtgt
    12721 aatgacactt gttacacgtc cttgcaatcc atactgtacg acgtcactgt ctttattaga
    12781 aagtttggag agtgcagtaa ccttgaagag attaccttga ttagtctttg tggcagattt
    12841 atcaatagtc tgaatcgttc cgttaattgt tagagtttgg tttccaactt tttcaagact
    12901 aagacgaaca ccttgctttt cttttaacaa tgagacatgc tctgaagtga cgtagtaggt
    12961 aatgaatact tcctttattt tttggatatc tgggtagatt tgagccacct cacttccatt
    13021 aggaatgaga gatttccctt caaattcact gtttagatgt atcgttcctg tttcaggagc
    13081 tataattata ttgttcttta gctgaatatt ggcttgctca atttgatttt taagttcagt
    13141 aatttgattt tcaactgtgg taagttgttg ggaagcattt tgcagaaatt gtgtttttaa
    13201 aatatctatt ttgatcctat gactagtgtc tggaagagaa aaatttcctg tactagcacg
    13261 ttggatacta aggtttgcca ttgaagattc aagttctgag atattttgtg ggatttgaga
    13321 aaggtattct tcttttaaag ctgagttatc ttcttgtgct tgaaattgag tttgatattt
    13381 ttttagggca gtttgatgtg gattctcagg tgaaagctta tattcttgat tattaatagc
    13441 ttgctttagc tcttcataat ctgtaatttt ttgatgaagt tcgtcaagct gactagtaat
    13501 aactgaaatg gcatgattag caagacttgc ttgattattg atttcagcat tttttttagc
    13561 aatcccaatg attatatctt gggtttgttc gagaaaatga ttaaacgtat cgctatagcc
    13621 gaattcatct tctcccttaa ataagttagt ttcttgttct agactggttc tgagtatttg
    13681 gagtccattt ttttgtttgt taagagtggc taattgtttt tctaaagctt ttttttgaga
    13741 attttccatt gtttttgagt attggataat aacatcacct ttcttaataa atttattgtt
    13801 ttttaaattg ttgacgacaa tagtatggtc actagttgat tggactgaag caataacttt
    13861 tgttggcgtc aattctcctt gtgaagtaat ggtaatttct tttttagcaa agagagcaaa
    13921 aataactaag aagctcacta acaaaacgga tggcaaaatc aagaaagttg caaagttatg
    13981 atgacgtcga tgataaaatt ccgcactttt aaaaaggttt ggattcatgt tattctcctt
    14041 aactactaaa taaatgatga tagaaacctt gtttagtcat taattcttga tgagatccta
    14101 tttcaataat tttgccctca tcaagcacaa tgacttgatt ggtccgcgct gaaatgctga
    14161 gacgatgagc tacgaaaata atagttttat ccgtcatagc caaaagatta tcaataaccc
    14221 tcttttcagt tagtacgtca agaccgcttg tagcctcatc tagaataagc acaggcgcct
    14281 tggttaggag agctctggca agtgcaattc gttgcttttg gcctcctgag agtccggcac
    14341 catcagaaag ctctgtttga tagcccatag gcatttgttc aatatcttgt cgaatttctg
    14401 caacctcaca agctcttaga atatcttcat gactagtaca gtcattagca cctaaggtta
    14461 aattttctaa aatagaacca ttaaaaatat aggcttgttg ggggagataa ttaatatgtt
    14521 ggcgaagact ttttttatca atcattttta agtcattatg attaatggta attcggccgt
    14581 tataaggctc aaaaaaatta acaatcattt tagctagagt cgttttacca gatccactaa
    14641 taccaacaag gctaactttg tccccttgct taatagtgag attaatattt gatagagtat
    14701 cgcgtccaaa gccatattta taggataact cttcaaattg aatgtctccg tgtaataatt
    14761 cttgattgac taatgtccca gcctcttgaa actcagaatc gactaggtaa acttcattga
    14821 gacgattatt agctaccttg gctgattgca gtttagtttg aagattaatg atattttcta
    14881 aaggattggt aaaataagat aagagagtat taaacgtaat caactgacca acagaaattt
    14941 ttcctcccat aactaatttg gccccaaacc ataagactat cacgttaagg attagttgcg
    15001 ccccttgttt gagactgctt tgtaaaatag agtacttact taacttgaag gatttatcca
    15061 gatagtccac aaattcacta tcaattttct gatagcgatt ttcttcactg gtcagtgatt
    15121 taatagtttc aatgccattg atatcttcga taatggctga gctaaccata gagttactct
    15181 gcatgacatc attattcatc ttttcaaatg ggtgcataaa tataaagata ataacaatat
    15241 atagagggac tgaaaccaga gatagaagaa aaagattggt attttgcact aacagaactg
    15301 tccctacgat agttaaaata ctgacatcaa gaaaaagaga caaaatagta gaagcgagtg
    15361 catcaataat agcattagca tctgtaaaac gtgagatgat ttctcctgtt ctgcgagttg
    15421 caaaaaaaga catgggaagc tcaaaaatat ggcgaatgta agataaaatg acgtcaatgc
    15481 ttaatcgctg actcagtaca gtcaggagat aatctcgcga aaaactcatc atctgtttga
    15541 ggatataggt aatgataaga ccaattgaaa taatgccgag tgttgatttc agttgatttg
    15601 gaatatagtc atctaatata ccttgtaggt aataagaacc tacaatatta atcagagtaa
    15661 cgagtaggct agctaatatg atatagaaaa tcagagatcg ctgtttaaaa atgagaggta
    15721 aaaagcttat tagaccgttc tttttgtcct tatgaggctt gtagctgggc tcgggtgcta
    15781 gaaaaatagc gacacccgtc cattcagaag taaatcgctc ctttgtcatc ttagtgactt
    15841 ttactgtcgg gtcagggtcg ccgattatca gataattttt tttgttttga tagacgacat
    15901 agtagtgttg gaatttacct tctttattaa catgaacaat aaaaggataa gggacatctt
    15961 ctatatcaaa gagggtcatg tctgcttgaa tagctcttgt ttcaaatccc attaatttgg
    16021 cagctttgac gatgccaagc gctgttgttc cctctttatt tgttttagct aactctctta
    16081 aatgagctaa agagtagtct gaaccgtaat atttagcgat ggaagcaaga gcagccacac
    16141 cacagtctct agcatcagtc tgagcaacaa atgtttttcg ataggatatc atttgtaaaa
    16201 gacctttcta ttaaatacta agctattatg acatatatat agggagtttt tatcaaaaat
    16261 cttaaaaggt atttataaaa gcatgaatgg tattatttaa acttcttaat taactattgt
    16321 cacagcgtaa gtgtagagag gataaaaaga catttcatga tgaaaaaacg gccttttaag
    16381 attttgaaac catgatactg ttctttatga tattctgtac tagtcgaggt tgcaacaaga
    16441 caaatttaag aattatgaaa agaagttatt cgatatggag ataaagaaac tggaaacatt
    16501 tcaccaaatg actatagaaa agcttgccaa ggttgagggt ggtaagaata attggcaggc
    16561 aaatgtcagt ggggttatcg ctgcaggtag tgctggagct gctataggtt ttccagtttg
    16621 cggtgtagcc tgtggttata ttggagctaa aacagctatt actctttggg ctggtgtaac
    16681 aggagctaca ggcggattct agaggaaagt aaggatgaca acaatgaagg aattaacaat
    16741 taatgacatg gctagtataa gtggaggaaa cgctccagga gatgctgtaa ttggtggtct
    16801 tggaggctta gcttctggat tgaaattttg taaactgcta catccagtat tggcaggtgg
    16861 atgtgttgta ggatttacag ttggtggagc atatttggga tatacagcaa attaaatgat
    16921 ctatacgatt tttattatta tgaatgcgtc tataatgttt ttaatcattg ttgatgccat
    16981 tcataaaaaa aatgttgata aatctatacc atatttagtg tttttaattt tcaatcaatt
    17041 atccctttcg gaaaaatcgg taaacatgtt atctatcgta gctttggtag cgtcatcatt
    17101 tgtttttatc gataaaagaa aatagtgatt atgccaatga atttagatat cactcttagc
    17161 tttttaaaat acaaaagagt gaaattaaaa tgaaaaagac ttcaaaaata tggaagtgct
    17221 aaaaaaatgg tctggctatc ataaatggag gcggaaaaga cggagcaaat atctttttga
    17281 cagggatggc aggtgctgag cagggagtga cagtttgtgc tcagacaggc gtatttatcc
    17341 cttggcaagg ttatattttg tgtggagcag ctggtgctgc tacaaatatt atctagcctc
    17401 actaaatata taaatgacta tctatcactg atatataagt agtagaggag tggtatgaaa
    17461 attttagata ttatttttaa cctatctgat agaaagatga tatttctaga aaatgttgaa
    17521 aagctgggag gttacattgt cccttttacc cttatcatct tgagtgtagc ctacaacttt
    17581 aggcaccctt atcctatttg ggctgctgta ctaggaggta tatcccttat tgtgatcttt
    17641 atttatttta tacttattgt ttatctatat ttgcgttata gatacttggt atgaaaaaaa
    17701 taccagaaat taagattaat tctactgagc tataatgcaa tcacatttaa ggggaaaatg
    17761 gatgacttat acaatatcag tacttatgat atttaacttt agagactaaa gagttaaaag
    17821 caaaatgcgt attgaaaatt ggttaaaaaa gttataactg tctctgataa caggaataat
    17881 aatttgttcg gttatatttg ctaccgatag agtagaggag gtgaagatat gcgtaatata
    17941 ttaagatttt taggtattgt tattatttct gcagtgattc tatttagtat aggtagtttc
    18001 tacgatttac cattaatgaa aaatatacaa cttatctgtt ggagttttat ccttgattta
    18061 ttcgtttttg tctacaaaca aagacaaacg acagaagtgc tcacatggta tcaagttgtt
    18121 aagcaatttt ggttatttat taagtgtact attcttattc ctaccttaat tgcttttatt
    18181 ataataatag gatgtttgac gagtatatca gaggtatcaa tttactttta tttacacctt
    18241 attgttgttt gctatacaat aggaatgatt ttatcattag gtcgtcttat ttctcctaat
    18301 cactctatat ttaataaact taaaaagtga aatgaatcat atttaaagtt tgtttttaaa
    18361 taatgggact agtttagtgt aaccgattca attaaagaat agttcgtgac aagaagatac
    18421 ctttgaagtt tcagaaataa tctgttttcc atcctgctat actcatcttt gccaaagctc
    18481 gtcattttat atgatttata tagaattacg ggttttttgt tagactaata tgagaaaata
    18541 tagcatgacg aattcctaaa taaaaaataa tgaaaggaac atgatgatgt taagagatgt
    18601 taaagttaaa atgagcagtt tattagttgg ttgtgcggct actttactag tcagtttgag
    18661 tagtacagtt gcggcagatt cagtccattc gtctgataga cgttttggag ttggctataa
    18721 ggaagaaaca acctctcagt tttcttcgga tcagccctcc caagtggttt tgtatcgagg
    18781 tgaggctaac acggttaggt ttacctatac caatcagatg tctctgatga aagatattcg
    18841 cattgctttg gatggttctg ataagtcttt gaccgctcag attgttcctg gtatgggtca
    18901 tgtttatgag ggctttcaaa cttctgctag agggattttt acgatgtcag gagttcctga
    18961 aagcactgtt cccgttgcta accctaatgt acaaaccaaa tatacaaggt atttcaaagt
    19021 cattgatgat atgcataaca caatgtataa aggaactgtt tttcttgttc aaccgcaagc
    19081 ttggaaatac accatgaaat ctgttgatca gttaccagta gatgacttga accatattgg
    19141 cgttgctggt attgaacgaa tgacaactct cattaaaaat gcgggtgccc ttttaaccac
    19201 aggaggtagt ggggctttcc cagacaatat taaagtatct attaatccaa aggggaggca
    19261 ggccacgatt acttatgggg acggctctac ggatattatt cctccagcag ttttatggaa
    19321 aaaaggctcc gtaaaagagc ctactgaagc cgatcaatct gtcggaacac cgactcctgg
    19381 tattcctggt aaattcaaac gagaccagag ccttaacgag catgaagcta tggtaaatgt
    19441 cgaaccactg tctcatgtag taaaagacaa tataaaggtc atagatgaaa aatcaacagg
    19501 gcggtttgag ccttttagac ctaatgaaga tgagaaggag aagcctgcca gcgatgttaa
    19561 ggtaagacca gcagaagttg gtagctggct agaaccagcg acagctcttc ctagtgttga
    19621 aatgagcgct gaggacaggt taaaaagtta gttaataatt tgccggttgc tttagacagg
    19681 caaacaggaa agggcttgga ggtttcttct gaagtagctg tgagcgcctc acagccggaa
    19741 gaattgcatc gattgcctaa ccgtttgata cctgaggaag acaataataa actatcacga
    19801 gtagccaagg aagtcgttac tgagccaagg ctaaataacc cctttttgtt acccaagaag
    19861 gttctttcgt tagaagatga tgctgctatc cttaatcatt tggaggaaga ccgtaatgtc
    19921 aataagttgt tcctcgagcc agttgcggct gaagccaaga gagaaattaa ttttcatcca
    19981 agtgaccagc aggtgactgc taaagttaag gagtcatctg attttcatca gaaacagcac
    20041 caaacaggga ttacttatgg agatgatact ctggcagatc tggcgcatca tttgcttcat
    20101 tcagatggtg ttattcctag tctaaatgat aagagtgctt aagaattatg tgctagtaag
    20161 tctcgctaag aagaggagtg ttacaagata aataaagaag aggtcaggga actaccggcc
    20221 tctttttgtc cgaaatagcg agaatgactc tagcttacct gtatgtaggt ccgtgctaca
    20281 catcttgtta atgataggga gctgggatca gaaaataatt ggtatatcgt tttctcctaa
    20341 ctttttaaga aagtgcgggc aaagtgggct gttagggtga tggggttgct ctttcatgat
    20401 cagtttttta gcttgaagaa agcgtggtga tgagattagc ttaaaaaaga acactaccga
    20461 aatggtagtg tccactgatt ttaggagagc taagattggt catctaacag gagtctaact
    20521 gtcatgctaa taacagattt gatagcgctg tccccacttg gaagaaatag agccttattt
    20581 ttattttttt tgtgtttaag ggcttctttt ttgtgagggt tttgttttga gtggcctatg
    20641 gtcatcgcag tccttttcct ttcaatagtg tgtttaggaa ttggtggttt agggctgacg
    20701 gcaagaataa aacacagtat gctaatagct aagataagat aaaactgttt tttggtcatt
    20761 gtttaggcct ttctagttga aaaatgtagt tgttgttagt ttagcctttt tggtagctgg
    20821 tatttaaaat agtattagcc aagtggttgt actggctatc taaacggtac tcagtattcc
    20881 tcacgtcttt tccagcaagg aaataccttg tggtgtatgc tgaatcattc caggtagcat
    20941 caacgtagga attaacacca tgaatggtaa cgatgtttca agtatggtgc tcattcaatc
    21001 cttttttatc acataccaag ttgataagcc tgcagcttct gccatatctt taaacatgac
    21061 ggcataagct tgacaagcac cacacttgcc acgataaaga gctttaggag tatgattgtt
    21121 gatgctgctt acggttttgc gattggtgct aagttatttt gtggcgtaag tgtattcgtt
    21181 gattaaatgg ttataaataa ccttagcctt gtcgtagtca ctggtgatcg gtttatctgt
    21241 aatatttttt tgacaaaggt tttatattcc ttatgaaggg ctaccaaatt gtctttaaga
    21301 gtataggtaa ctgtaatatc attgttaacc atgatacgtt ggctttgtct accaagtgta
    21361 taagtactgg tacgactttg ggaagtaaat gaagtaaggg ttccataata atcacctcat
    21421 tcgtcgagag tggcaccagg tcgttgctgg ttaatggagc tgatagtttg atagtaagtg
    21481 ttttgtttag acacatcata acggtatgcc cctgctgttt catcagcttt gaccttgctg
    21541 tcaatggcag caaacgcact taagagtaaa gctgccgcta ggtcgctaac actcttttta
    21601 atatctatta gttttcctgt tacaaactaa atataagggt ttcccaaaag tggattgttt
    21661 ttaagcgaaa ggttatccac caacgataat caggatatcc at
//
