LOCUS       NZ_LT963352            22700 bp    DNA     linear   CON 13-FEB-2024
DEFINITION  Streptomyces chartreusis NRRL 3882 isolate NRRL3882 chromosome I.
ACCESSION   NZ_LT963352
VERSION     NZ_LT963352.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces chartreusis NRRL 3882
  ORGANISM  Streptomyces chartreusis NRRL 3882
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wibberg,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2017) CEBITEC, Genome Research of Industrial
            Microorganisms (GRIM), Universitaetsstrasse 27, 33615, NRW, Germany
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 02:03:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,073
            CDSs (total)                      :: 7,984
            Genes (coding)                    :: 7,779
            CDSs (with protein)               :: 7,779
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 205
            CDSs (without protein)            :: 205
            Pseudo Genes (ambiguous residues) :: 0 of 205
            Pseudo Genes (frameshifted)       :: 91 of 205
            Pseudo Genes (incomplete)         :: 161 of 205
            Pseudo Genes (internal stop)      :: 14 of 205
            Pseudo Genes (multiple problems)  :: 56 of 205
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:02:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6075770
            Orig. end                         :: 6098470
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT963352.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22700
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="21"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22700
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22700
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12700](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12700)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(882..897)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.28"
                     /tool="antismash"
     gene            1073..2140
                     /locus_tag="SCNRRL3882_RS27460"
                     /old_locus_tag="SCNRRL3882_5395"
     CDS             1073..2140
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004988313.1"
                     /locus_tag="SCNRRL3882_RS27460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5395"
                     /product="PhoH family protein"
                     /protein_id="WP_029181327.1"
                     /transl_table=11
                     /translation="MTQTPTAHTPAQEQARAQFTVPAQHPMVTVLGSGDSLLRVIEKAF
                     PAADIHVRGNEISAVGDPVDVALIARVFDEMMLVLRTGQPMTEDAVERSIAMLKASENG
                     ESDGQETPAQVLTQNILSSRGRTIRPKTLNQKRYVDAIDKHTIVFGIGPAGTGKTYLAM
                     AKAVQALQSKQVNRIILTRPAVEAGERLGFLPGTLYEKIDPYLRPLYDALHDMLDPDSI
                     PRLMAAGTIEVAPLAYMRGRTLNDAFIILDEAQNTSPEQMKMFLTRLGFDSKIVITGDV
                     TQVDLPDGTKSGLRQVQDILDGVDDVHFSRLSSHDVVRHKLVGRIVDAYEQYDTKHGTQ
                     NGAHKSRGKAGHKGK"
     gene            2155..2652
                     /gene="ybeY"
                     /locus_tag="SCNRRL3882_RS27465"
                     /old_locus_tag="SCNRRL3882_5396"
     CDS             2155..2652
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ybeY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957737.1"
                     /locus_tag="SCNRRL3882_RS27465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5396"
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="WP_010042065.1"
                     /transl_table=11
                     /translation="MSIDVNNESGTEVDEQAILDIARYALARMRIHPLSELSVIVVDAD
                     AMEQLHIQWMDLPGPTDVMSFPMDELRPPSKDDDEPPQGLLGDIVLCPEVAEKQGKEAD
                     TQHSMDEELQLLTVHGVLHLLGYDHEEPDEKAEMFGLQAAIVDGWRAERGLTGPSPAPT
                     VS"
     gene            2660..3964
                     /locus_tag="SCNRRL3882_RS27470"
                     /old_locus_tag="SCNRRL3882_5397"
     CDS             2660..3964
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990145.1"
                     /locus_tag="SCNRRL3882_RS27470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5397"
                     /product="hemolysin family protein"
                     /protein_id="WP_010042067.1"
                     /transl_table=11
                     /translation="MSPQLALGAVALVVVAWLAACAEAGLARVSSFRAEEAVRSGRRGS
                     AKLSQVAADPTRYLNVALLVRVACEMAAAALITYGCLKEFDGTTEALLIAIAVMVLVSY
                     VAVGVSPRTIGRQHPLNTATLSAYVLVPLARIMGPIPSLLILIGNALTPGKGFRRGPFA
                     SEAELRALVDLAEKESLIEDEERRMVHSVFELGDTLVREVMVPRTDLVVIERFKTIRQA
                     LTLALRSGFSRIPVTGESEDDIVGIVYLKDLVRKTHISREAESEQVSTAMRPAFFVPDT
                     KNAGDLLREMQKERNHVAVAVDEYGGTAGIVTIEDILEEIVGEITDEYDRELPPVEDLG
                     KDRYRVTARLDIGDLGELYGLEAFDDEDVETVGGLLAKALGRVPIAGASSVVGLPDGRE
                     LRLTAEAAAGRRNKIVTVLVEPVDPADPPEEEKPE"
     gene            3961..4320
                     /locus_tag="SCNRRL3882_RS27475"
                     /old_locus_tag="SCNRRL3882_5398"
     CDS             3961..4320
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1198: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660475.1"
                     /locus_tag="SCNRRL3882_RS27475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5398"
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="WP_010042069.1"
                     /transl_table=11
                     /translation="MTPQELRAFCLSFNAAVEDFPFSPEISVFKVQGKLFALSHLDARP
                     LKVNLKCDPDDAIRLRREHEGLIVPGWHMNKRHWNTVTADGGLPDRLVRELVEDSYDLV
                     VAGLPRADRLRLDRS"
     gene            4341..4694
                     /locus_tag="SCNRRL3882_RS27480"
                     /old_locus_tag="SCNRRL3882_5399"
     CDS             4341..4694
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381927.1"
                     /locus_tag="SCNRRL3882_RS27480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5399"
                     /product="hypothetical protein"
                     /protein_id="WP_010042071.1"
                     /transl_table=11
                     /translation="MTDSSALDPEDRKIVTLARSARARNGVPEGAAVRDETGRTYVAGT
                     VALDSLRLSALQTAVAMAVASGATSLEAAAVVTEAETASAEDRAAVRDLGGAGTPVLIA
                     GPDGTVRATVTAG"
     gene            4877..5353
                     /locus_tag="SCNRRL3882_RS27485"
                     /old_locus_tag="SCNRRL3882_5400"
     CDS             4877..5353
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042073.1"
                     /locus_tag="SCNRRL3882_RS27485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5400"
                     /product="hypothetical protein"
                     /protein_id="WP_010042073.1"
                     /transl_table=11
                     /translation="MRCKRIGAGAALAAGALAVTGLAFAPAALAVTPQTATISADCGTF
                     GSGEATLTATQDGTAATVTVKSSAITAPIGLGEDSIASTLTLVKTGGGTVDFTGTENPA
                     MAAGAPVEVGPLSGTVASGDSLEAFGGSLKMTVFGITITCTATGPQSPGPFVFD"
     gene            complement(5376..5714)
                     /locus_tag="SCNRRL3882_RS27490"
                     /old_locus_tag="SCNRRL3882_5401"
     CDS             complement(5376..5714)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018850023.1"
                     /locus_tag="SCNRRL3882_RS27490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5401"
                     /product="P-II family nitrogen regulator"
                     /protein_id="WP_010042075.1"
                     /transl_table=11
                     /translation="MKLITAIVKPYRLDEIKNALQELGVQGLTVSEASGYGRQRGHTEV
                     YRGAEYQVDLVPKVRIEVVVEDADAEAVIDAVVKAAHTGKIGDGKVWALPVDTVVRVRT
                     GERGPDAL"
     gene            complement(5711..7021)
                     /locus_tag="SCNRRL3882_RS27495"
                     /old_locus_tag="SCNRRL3882_5402"
     CDS             complement(5711..7021)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008519 - ammonium transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042078.1"
                     /locus_tag="SCNRRL3882_RS27495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5402"
                     /product="ammonium transporter"
                     /protein_id="WP_010042078.1"
                     /transl_table=11
                     /translation="MPLAAASADTGDTAWLLAATALVLLMTPGLALFYGGMVRTKSVLN
                     MLMMSFVSIALVTVVWLAAGYSLAFGEDAAGGLIGGLDHAGMSGLGPDSVQGTVPTLLF
                     ATFQLTFAIITAALVSGAVADRAKFGAWLVFVPVWALLVYVPVAHWVWGPGGWILDRLG
                     ALDFAGGLPVEIVSGASGLALCLVLGPRLGFKKDAMRPHNLPMVMLGAGLLWFGWFGFN
                     AGSALGANGLAAAAFLNTLAAGCTGLLGWLFVEQKRDGHPTTLGAASGAVAGLVAITPS
                     CGSVSLLGALVVGLTAGAVCSYAVSWKFKLNYDDSLDVVGVHLVGGVIGTLLIGVFAVE
                     SMTGGAEGLLYGGGLGQLGKQLLAVVVVAVYAFGVTYGIGKLIDATMGFRASEEQEQTG
                     LDLTVHAETAYDHGVLGHGAPVSSSVVSSAQKVTPQA"
     gene            7194..8156
                     /gene="era"
                     /locus_tag="SCNRRL3882_RS27500"
                     /old_locus_tag="SCNRRL3882_5403"
     CDS             7194..8156
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="era"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976264.1"
                     /locus_tag="SCNRRL3882_RS27500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5403"
                     /product="GTPase Era"
                     /protein_id="WP_086012539.1"
                     /transl_table=11
                     /translation="MGAMSVRTQSSEEPAEAVHRAGFACFVGRPNAGKSTLTNALVGQK
                     VAITANQPQTTRHTVRGIVHRPDAQLILVDTPGLHKPRTLLGERLNDVVRTTWAEVDVI
                     GFCLPANEKLGPGDRFIAKELASIKKTPKIAIVTKTDLVDGKALAEQLIAIDQLGKELG
                     FEWAEIVPVSAVGDKQVGLLADLIVPLLPEGPALYPEGDLTDEPEQVMIAELIREAALE
                     GVRDELPHSIAVVVEEMLPREDRPADKPLLDIHAFVYIERPSQKGIIIGPKGKRLKEVG
                     IKSRKQIEALLGTPVFLDLHVKVAKDWQRDPRQLRKLGF"
     gene            complement(8197..10023)
                     /locus_tag="SCNRRL3882_RS27505"
                     /old_locus_tag="SCNRRL3882_5404"
     CDS             complement(8197..10023)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990138.1"
                     /locus_tag="SCNRRL3882_RS27505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5404"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_010042082.1"
                     /transl_table=11
                     /translation="MKPRATGETDERSRTAPRDFLRLLHGHRRWVALAVLLTLGASALS
                     LAQPLLVKQVIESTTSGSAIGTALVLLVVLFLAQALVQGLAQFVLARTGEGIVLGIRLG
                     LIKHVLRLPMAVYDRHRIGDLISRTSTDSTTLRLLVAEGFTEAITGVIGLIGVVALMIW
                     LDWLMFLVVLGMVAIATMIVVSVLHGIEVASLSTQRATGAMTADLERALGAIRTVRASR
                     AEQRETDRIADGARSAYAGSVRMAKLDAVVAPAIQLAVKGSFVVVLLIGGMRVADRQGS
                     IADLAAFLLYMIYLVEPIGMLFQSLSTMEQGVGAYRRVTEVLELPTEQDAVSGAGAPVS
                     RPAGGSGGRSRAPALEFRDVWFGYEPRRPVLRGVTFEAPEHSHVALIGSSGVGKSTVFA
                     LIERFYDPDSGHILAEGRDIRASGRAEHRARIGLVEQHAPVLYGTLRENLMYAVPDAEP
                     EELDRVVELAHLSDLITRLPRGLDTDAGEHGMALSGGERQRIAIARALLARPRLLLLDE
                     PTAHLDAVSEAALRRSMREATRECTLLVIAHRMSTIHAADLIVVLDAGRVVATGSHGEL
                     LDSSEHYRSLLRAQQTGDLRVPRTAGLKGGAG"
     gene            complement(10001..10474)
                     /locus_tag="SCNRRL3882_RS27510"
                     /old_locus_tag="SCNRRL3882_5405"
     CDS             complement(10001..10474)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990137.1"
                     /locus_tag="SCNRRL3882_RS27510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5405"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_010042084.1"
                     /sec_met_domain="PF13471 (E-value: 1.4e-25, bitscore: 88.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPEVIFHDPRSVPLRRRIPVRLAVGAARLLARQRPRRIRAALE
                     WLRRGARPATLGQTRAARDSVVAVSLACGGREGCLPRSLATVLLCRLHGQWPTWCVGAR
                     RLPPFGAHAWVEAEGVPVGEEHPPDYFRPLFTVPCVPGSVRREAVIHEAPSDG"
     gene            complement(10471..10851)
                     /locus_tag="SCNRRL3882_RS27515"
                     /old_locus_tag="SCNRRL3882_5406"
     CDS             complement(10471..10851)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990136.1"
                     /locus_tag="SCNRRL3882_RS27515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5406"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_010042086.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.1e-18,
                     bitscore: 65.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.5e-11, bitscore: 40.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFKLREGVFTAETDYGIAILDEDRNQYWTLNPSAAVALHTLLAG
                     GSEDDAAQTLSAEYAVDIGTARRDVRDLVGGLYSAGLGEADSDGPGEGARAPTARPVGL
                     VRRRMGGRWPHLRGRRAGRERR"
     aSDomain        complement(10606..10848)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SCNRRL3882_RS27515_Stand_Alone_Lasso_
                     RRE.1"
                     /evalue="4.00E-21"
                     /identifier="RREFam002.1"
                     /label="SCNRRL3882_RS27515"
                     /locus_tag="SCNRRL3882_RS27515"
                     /protein_end="82"
                     /protein_start="1"
                     /score="65.8"
                     /tool="antismash"
                     /translation="AFKLREGVFTAETDYGIAILDEDRNQYWTLNPSAAVALHTLLAGG
                     SEDDAAQTLSAEYAVDIGTARRDVRDLVGGLYSAGL"
     gene            complement(10865..12700)
                     /locus_tag="SCNRRL3882_RS27520"
                     /old_locus_tag="SCNRRL3882_5407"
     CDS             complement(10865..12700)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042088.1"
                     /locus_tag="SCNRRL3882_RS27520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5407"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_010042088.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.2e-37, bitscore:
                     129.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDFPGSGEGPGWFVVLPDCASAARVSAALRTRKVQEVSHPSGRP
                     WLLGHWSPGAMAVGEAGRTKIAVVGEHAVTADRLTPAADRIRTISDLDGLARGLAGSWH
                     LVASVAGRVRVQGSVTGFRRVFHARLEDTTVAADRADVLAALLDAEVDEQRLAARLLNP
                     CAPHPLAGEPVWRGVGALGIGRYLALDADGRGRPVAWWAPPEPVVPMAEGASALRKALS
                     AAVEVRVRGRDVVSCDLGGLDSTSVCALAARGTAKVIAYTADGLDPLCDDVTWARRTVA
                     RLGDVGHHVIAGDQLPMVYEGLRDVDERFDEPCPAMMHPSRCLLIPRLAAAQGSRIHLT
                     GFGGDELLSGSPAHLHTLARTHPRIAWQRLRGFAAQGPWPYREALRQLWDNSSYRTWLG
                     RAGDLLTAVPPPLETPALDWGTPPRLPPWATPDAVAAVRELIRTAARTAEPLAERRGQH
                     IELEAMGNNSRMVRQVGQMASRAGLTLAAPYYDDRVVEAGLAVRPQDRITPWQYKPLIV
                     EAMRGIVPDESLTRHTKDEGSYEAEVGMREQRAELLALCEDSRLARLGLIDAKVLRETC
                     GRPLPPSLPFDALYQTVVCEMWLRTLETATTAVPG"
     gene            complement(12810..12923)
                     /locus_tag="SCNRRL3882_RS40570"
                     /old_locus_tag="SCNRRL3882_5408"
     CDS             complement(12810..12923)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF039305.3"
                     /locus_tag="SCNRRL3882_RS40570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5408"
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_107500549.1"
                     /transl_table=11
                     /translation="MRTYERPTLTAVGSFRKTGLGFRDGPERFWFFRRRFF"
     CDS_motif       complement(12864..12923)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MRTYERPTLTAVGSFRKTGL"
                     /locus_tag="SCNRRL3882_RS40570_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(12810..12863)
                     /prepeptide="core"
                     /locus_tag="SCNRRL3882_RS40570_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-7.70"
                     /molecular_weight="2305.6"
                     /monoisotopic_mass="2304.2"
                     /core_sequence="GFRDGPERFWFFRRRFF"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MRTYERPTLTAVGSFRKTGL"
                     /leader_location="[12863:12923](-)"
     misc_feature    complement(13027..13042)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.76"
                     /tool="antismash"
     gene            complement(13059..13511)
                     /locus_tag="SCNRRL3882_RS27525"
                     /old_locus_tag="SCNRRL3882_5409"
     CDS             complement(13059..13511)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070168.1"
                     /locus_tag="SCNRRL3882_RS27525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5409"
                     /product="ATP-binding protein"
                     /protein_id="WP_010042090.1"
                     /transl_table=11
                     /translation="MSPHTTSTPRFLDAVRPGRTHWLELPSHRTSVRVARHATQARLDS
                     WQVPDEACANAVLVVSELVTNAVLHTPGERILCGVGRMTAERFRLEVHDGDLTGRGIPD
                     CRPALDDEGGRGLLLVREIADSWGVTRSPLTGGNAVWASLATTQCP"
     misc_feature    complement(13605..13620)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.21"
                     /tool="antismash"
     misc_feature    13650..13664
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.83"
                     /tool="antismash"
     misc_feature    complement(13660..13674)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.72"
                     /tool="antismash"
     gene            13758..14630
                     /locus_tag="SCNRRL3882_RS27530"
                     /old_locus_tag="SCNRRL3882_5410"
     CDS             13758..14630
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020120167.1"
                     /locus_tag="SCNRRL3882_RS27530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5410"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_010042092.1"
                     /transl_table=11
                     /translation="MNDARSGTGAGAPTVLRMILGRRLQEARQTAGLSLDDAAKALRVT
                     PLTIRRLEKAEVGLKILYVEKLLQTYGAEQQEIDEFVSLAERANEPGWWHPYRDVMPSW
                     FTAYVSLETGARTLRTYEPQYVTGLLQTPGYARAVLRGGFPNDNDEDLQRRVELRLRRQ
                     SLLTKPDAPTLWVVMEEAVLHRVVGGPEVMREQIDRLLEASELEHVSVDIVPFTAGAHV
                     GACAPFTYFRFEERELPDIVYSEILSASVYLDQRADVVAHLEAHNRLSLKTSSADSKAL
                     LNRMRKEYS"
     gene            14627..14878
                     /locus_tag="SCNRRL3882_RS27535"
                     /old_locus_tag="SCNRRL3882_5411"
     CDS             14627..14878
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990132.1"
                     /locus_tag="SCNRRL3882_RS27535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5411"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_010042095.1"
                     /transl_table=11
                     /translation="MTIAEGAVYNGMPASDLGEQGWERPWSGPNGGQCVETKQLADGRV
                     AVRQSADPAGPALIYTPEEITAFVAGVKQGLADHLTAL"
     gene            14947..15759
                     /locus_tag="SCNRRL3882_RS27540"
                     /old_locus_tag="SCNRRL3882_5412"
     CDS             14947..15759
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019056841.1"
                     /locus_tag="SCNRRL3882_RS27540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5412"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_010042096.1"
                     /transl_table=11
                     /translation="MTHSHASRDIDTSRPHSARMYDYYLGGKDHFEVDKQAAERVAEAY
                     PAIFVCARENRAFMHRATRVLAREHGIRQWLDIGTGIPTEPNLHQVAQSVVPDARVVYA
                     DNDPLVLKYAERLMRSTAEGRTTYIEADVNDPQALLTAPELAEVLDLSRPVALSLNALM
                     HFVTDAQDPYGIVRRLLDVLPSGSALALSHCTPDFDPSTWQKVTEIYTSAGTPVQFRSR
                     ADVTRFFDGLELLDPGVTVGHRWRPDATDGDAPTDAEVSLWTGVGVKP"
     gene            complement(15749..17071)
                     /locus_tag="SCNRRL3882_RS27545"
                     /old_locus_tag="SCNRRL3882_5413"
     CDS             complement(15749..17071)
                     /EC_number="3.2.1.21"
                     /GO_function="GO:0008422 - beta-glucosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030245 - cellulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001391.1"
                     /locus_tag="SCNRRL3882_RS27545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5413"
                     /product="GH1 family beta-glucosidase"
                     /protein_id="WP_010042098.1"
                     /transl_table=11
                     /translation="MATDAGNPIPRFPAGFLWGVSTSAHQIEGAADEREPSVWDAFTAE
                     PGRVKDGSTAVVACDHYHRHREDVALLAGLGVNAYRFSVSWPRVRSEKGLDFYDRLVDD
                     LCAAGIRPVPTLFHWDLPTDLDWLERDTAARFAEYAALVAGRLGDRVTKWITLNEPAEH
                     TLLGHALGVHAPGRQLLFDALPAAHHQLLAHGLAVRALRASGVTDIGIANSHGPTWAAS
                     TEAADAEAAEFYDVLLNRLFADPLLLGRYPDGIGELMPGDVAADLKVIAEPVDWYGVNY
                     YAPTRVGAPQGTDITFGGVAMPAELPFSVREITGHPVTDFGWPVVPEGLTELLTTFHDR
                     YGDRLPPVVITENGCSYPDVDDQDRIAYLDGHIRALHRALEAGVDVRGYFVWSLLDNFE
                     WAEGYARRFGLVHVDFETLERTPKSSYRWYREVLRAQGTTV"
     gene            complement(17143..17409)
                     /locus_tag="SCNRRL3882_RS27550"
                     /old_locus_tag="SCNRRL3882_5414"
     CDS             complement(17143..17409)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116275.1"
                     /locus_tag="SCNRRL3882_RS27550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5414"
                     /product="protealysin inhibitor emfourin"
                     /protein_id="WP_010042100.1"
                     /transl_table=11
                     /translation="MRIQVRRTGGFAGIERHAEVDTSGRPDAPEWHALAEKAFAAGRST
                     PPIGVPDGFGYQITVDGKTVYCADPRLTEEQRKLISRVLKEGA"
     gene            complement(17430..18491)
                     /locus_tag="SCNRRL3882_RS27555"
                     /old_locus_tag="SCNRRL3882_5415"
     CDS             complement(17430..18491)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028408.1"
                     /locus_tag="SCNRRL3882_RS27555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5415"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_029181328.1"
                     /transl_table=11
                     /translation="MTTHGGFEPVFCTIVPPHVLDKLAQAEDPALAGPARRTLQRDAFE
                     RTQRRLTTVIGATAVTGVADGKPQRTIHDARHGTDLPGHKVRGEGDKPGKDATVNRAYA
                     GLGATFELLWRAYQRDSIDGGGLPLNATVHYDRDYNNAFWNGEQMVFGDGDGEIFLDFT
                     IPIDVIGHELVHGVTQYTANLTYFGQPGALNESLSDVFGSLIKQYTLGQTAAEADWLIG
                     AGLLAPRVTGKALRSMKEPGTAYDDDVLGKDPQPATMDDFVRTGRDNGGVHINSGIPNH
                     AFYLAATALGGHAWERAGQVWYDVLTGGELKQQAMFADFATLTVKAARERFGDGEELDA
                     VSKAWEQVGVRTL"
     misc_feature    complement(18512..18527)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     gene            18811..20532
                     /gene="leuA"
                     /locus_tag="SCNRRL3882_RS27565"
                     /old_locus_tag="SCNRRL3882_5416"
     CDS             18811..20532
                     /EC_number="2.3.3.13"
                     /GO_function="GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660485.1"
                     /locus_tag="SCNRRL3882_RS27565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5416"
                     /product="2-isopropylmalate synthase"
                     /protein_id="WP_010042103.1"
                     /sec_met_domain="HMGL-like (E-value: 3.7e-74, bitscore:
                     248.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANRQQPSSMPIHKYGRYEQVDIPDRTWPNNRITAAPRWLSTDLR
                     DGNQALIDPMSPARKRAMFDLLVKMGYKEIEVGFPASGQTDFDFVRSIIEEPGAIPDDV
                     TISVLTQAREDLIERTVESLKGAKRATVHLYNATAPVFRRVVFRGSKDDIKQIAVDGTR
                     LVMEYAEKLLGPETEFGYQYSPEIFTDTELDFALEVCEAVMDVWQPGPGREIILNLPAT
                     VERSTPSTHADRFEWMGRNLSRREHVCLSVHPHNDRGTAVAAAELALMAGADRVEGCLF
                     GQGERTGNVDLVTLGMNLFSQGVDPQIDFSDIDEIRRTWEYCNQMEVHPRHPYVGDLVY
                     TSFSGSHQDAIKKGFDAMEADAKAKGVTVDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQ
                     SGKGGIAYVLKNDHKLELPRRMQIEFSKIIQAKTDAEGGEVTPKDIWAVFQDEYLPNPE
                     NPWGRIQVKNNQSTTDTDGVDTLTVEATVDGQDTVLSGSGNGPISAFFDALQSVGIDVR
                     LLDYQEHTMSEGASAQAASYIECAIDDKVLWGIGIDANTTRASLKAVVSAVNRATR"
     misc_feature    20617..20632
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     gene            20719..21417
                     /locus_tag="SCNRRL3882_RS27570"
                     /old_locus_tag="SCNRRL3882_5417"
     CDS             20719..21417
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990125.1"
                     /locus_tag="SCNRRL3882_RS27570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_5417"
                     /product="TerB family tellurite resistance protein"
                     /protein_id="WP_010042104.1"
                     /transl_table=11
                     /translation="MLPGRGRNGHAARFSSILGTRTAWTPAGDGEFFCPGCGGDRNYQR
                     LTGQRRFTLLGLPVLPRGETGPVVECAACRRHFGTDVLDHPTTTRFSAMLRDAVHTVAL
                     AVLAAGGAGSRPALEAAVLAVRAAGFDDCTEEQLAALVEALEADTGRITGEPCGAGLAI
                     ELHEALDPLAPHLATVGRESILLQGARIALADGPYTPAERDVLATVGAALTICSDDVTR
                     VLAEAARTPS"
ORIGIN
        1 agggggagcg cacgatggtc tcgcacggcc atgagccgcc cccggaggag cccgcccccg
       61 agtgcccgcc gcgcgcgcgt gccgccgtcg cctccctcgc ccccggcgtc agcgcgccct
      121 ggatcgccca ggccgcgagc aagggcaccc gggtcttcgg cgacgtcggc tgggacgaca
      181 ccggcgcgtg ggacctggcg gcgctgcccg acctgcggca ctgcgaggcg ttcctgccga
      241 acgcggagga ggccatgcgg tacacgggcg cggactgccc cagggcggcg gcgcacgcgc
      301 tgaccgacca cgtgccgctc gcggtcgtca cgctcggggc ggacggggcg tacgcggtgg
      361 accggcgtac gggggagacg gcggaggttc cggcgatcga ggtcgaggcg ctcgatccga
      421 ccggggcggg ggacgtgttc gtcgccgggt tcgtgaccgg gaccctggcg gactggccgc
      481 tggcggaccg gctggccttc gccgggctga cggcggcgct gtcggtgcag gagttcgggg
      541 ggtcgttgtc ggcgccgggg tggtcggaga tcgcggcgtg gtggcggagg gtgcagtcgg
      601 tcgaggggca ggatccggag gccctgcagc ggtacgggtt ccttgcaggg ctggtgtcgg
      661 aggagttgat gaggccctgg ccgctgcggc gggccgtacc tacgatcggc ttccggcgct
      721 cggcgtgacc tcctggcctc ccagggggct ccgctccctg gacccccggc ctgtgcccac
      781 ccgccaccga atcaccccgt caagagccgc cgtcgccccc gaagcggtca gccgggtggc
      841 acggccgccc cgaatcactc ggccgccagg caccgccgcc ccggatcaac cggtcaagag
      901 ccgccgtcat ccccgaagcg gtcggttgcc acggcctgtc gcccccgttt ccaaccccgc
      961 ccccaaaacc cctacggcgt tgtcagtccc ccgtcgtacc ctgggaatcg cgaggccgcc
     1021 ctcagctacg cggccgtgaa gaggaggaac cgcaggcctt cagcgccggc ccatgactca
     1081 gacacccaca gctcacaccc ccgcgcagga gcaggcgaga gcgcagttca ccgtccccgc
     1141 ccagcacccc atggtgaccg tgctgggttc cggcgactcc ctcctgcgcg tgatcgagaa
     1201 ggccttcccg gcggccgaca tccacgtccg gggcaacgag atcagcgcgg tcggcgaccc
     1261 cgtggacgtc gccctcatcg cccgcgtgtt cgacgagatg atgctggtgc tccgcaccgg
     1321 acagccgatg acggaggacg cagtggaacg ctcgatcgcc atgctcaagg cgagcgagaa
     1381 cggggagagc gacggccagg agaccccggc ccaggtgctc acgcagaaca tcctgtcctc
     1441 gcgaggccgc acgatccgcc ccaagacgct caaccagaag cgctacgtgg acgcgatcga
     1501 caagcacacg atcgtcttcg gcatcggccc cgccggcacc ggcaagacct acctggcgat
     1561 ggccaaggcg gtgcaggccc tgcagtccaa gcaggtcaac cgcatcatcc tgacccgccc
     1621 ggcggtcgag gccggagagc ggctcggatt cctcccgggc acgctctacg agaagatcga
     1681 cccgtacctg cgcccgctct acgacgcgct gcacgacatg ctcgacccgg actccatccc
     1741 ccggctgatg gcggcgggca cgatcgaggt cgcgccgctc gcctacatgc gcggccgcac
     1801 gctcaacgac gccttcatca tcctggacga ggcccagaac acgagccccg agcagatgaa
     1861 gatgttcctc acccgcctcg gcttcgactc gaagatcgtg atcacgggtg acgtgacgca
     1921 ggtcgacctc ccggacggga cgaagagcgg tctgcgccag gtgcaggaca tcctggacgg
     1981 cgtcgatgac gtccacttct cccggctgtc gtcccacgat gtcgtccggc acaagctcgt
     2041 gggccgtatc gtcgatgcgt acgagcagta cgacaccaag cacggcaccc agaacggcgc
     2101 gcacaagagc cgcggcaagg ccgggcacaa ggggaagtag acacacacag caccatgtcg
     2161 atcgacgtca acaacgagtc cggcaccgag gtcgacgagc aggcgatcct cgacatcgcc
     2221 cgttacgcgc tcgcgcggat gcgcatccac ccgctctccg agctctcggt gatcgtcgtg
     2281 gacgccgacg ccatggagca gctccacatc cagtggatgg acctgccggg ccccacggat
     2341 gtcatgtcct tcccgatgga cgagctgcgc ccgccgtcca aggacgacga cgagccgccg
     2401 caggggctgc tcggcgacat cgtgctgtgc cccgaggtcg ccgagaagca gggcaaggaa
     2461 gcggacacgc agcactccat ggacgaggag ctccagctcc tcaccgtcca cggcgtgctg
     2521 cacctgctcg gctacgacca cgaggagccg gacgagaagg ccgagatgtt cggcctccag
     2581 gcggccatcg tggacggctg gcgcgcggag cggggcctga ccggcccgtc cccggcgccg
     2641 acggtctcct gagccgccga tgagtcccca actcgccctg ggcgcggtcg ccctggtcgt
     2701 cgtggcctgg ctcgccgcct gcgcggaggc gggcctcgcg cgcgtctcca gcttccgcgc
     2761 ggaggaggcc gtgcgctccg gccgccgcgg cagcgccaag ctgtcccagg tcgccgccga
     2821 cccgacccgc tacctgaacg tggcgctgct ggtccgcgtc gcctgcgaga tggccgccgc
     2881 cgcgctgatc acctacggct gcctgaagga gttcgacggc acgaccgagg ccctcctgat
     2941 cgccatcgcg gtcatggtcc tcgtgtcgta cgtcgccgtc ggcgtctccc cgcgcaccat
     3001 cggccgccag cacccgctga acacggcgac gctctcggcg tacgtcctgg tgccgctggc
     3061 ccggatcatg ggcccgatcc cgtcgctgct catcctcatc ggcaacgcgc tcacccccgg
     3121 caagggcttc cgccgggggc ccttcgcctc cgaggcggag ctgcgcgcgc tggtcgacct
     3181 cgccgagaag gaatcgctca tcgaggacga ggagcgccgc atggtgcact cggtcttcga
     3241 gctgggcgac accctcgtcc gggaggtcat ggtcccgcgc acggacctgg tggtcatcga
     3301 acgcttcaag accatccgcc aggccctcac cctcgccctg cgctccggct tctcgcggat
     3361 cccggtgacc ggcgagagcg aggacgacat cgtcgggatc gtgtatctga aggacctggt
     3421 ccgcaagacg cacatcagcc gcgaggccga gtccgagcag gtgtccacgg cgatgcgccc
     3481 ggcgttcttc gtgcccgaca ccaagaacgc gggcgacctg ctgcgcgaga tgcagaagga
     3541 gcgcaaccac gtcgccgtcg ccgtcgacga gtacggcggc accgccggca tcgtcaccat
     3601 cgaggacatc ctcgaggaga tcgtcggcga gatcaccgac gagtacgacc gcgaactgcc
     3661 gccggtggag gacctcggca aggaccgcta ccgggtcact gcccgcctgg acatcggcga
     3721 cctgggcgag ctgtacggcc tggaggcgtt cgacgacgag gacgtcgaga cggtcggcgg
     3781 tctgctggcg aaggcgctgg gccgggttcc catcgccggt gcgtcgtccg tcgtcggtct
     3841 cccggacggc agggaactgc gcctgaccgc tgaggccgcg gccggccgcc ggaacaagat
     3901 cgtgaccgtg ctggtggagc cggtggatcc ggcggatccc cccgaggagg agaagccgga
     3961 atgactccgc aggaactgcg cgcgttctgc ctgtcgttca acgcggcggt cgaggacttc
     4021 ccgttcagcc cggagatctc ggtcttcaag gtccagggca agctcttcgc cctgtcgcac
     4081 ctcgacgcgc gtcccctgaa ggtcaacctc aagtgcgacc cggacgacgc gatccggctg
     4141 cgccgcgagc acgagggcct gatcgtcccc ggctggcaca tgaacaagcg gcactggaac
     4201 acggtcacgg ccgacggggg actcccggac cggctggtcc gggagctcgt cgaggactcc
     4261 tacgacctcg tcgtcgcggg cctgccgcga gcggaccgcc tccgcctcga ccggtcctga
     4321 cgcttacgta tgctcggatc atgaccgaca gcagcgcgct cgaccccgag gaccgcaaga
     4381 tcgtcaccct ggcccgttcc gcacgggccc gcaacggcgt gcccgagggg gcggccgtac
     4441 gggacgagac cggacgtacg tatgtcgcgg ggaccgtggc cctcgactcc ctgaggctca
     4501 gtgccctcca gacggcggtg gcgatggcgg tggcctcggg cgcgacgtcg ctggaggcgg
     4561 cggcggtcgt gacggaggcg gagacggcgt ccgccgagga ccgggcggcg gtacgggatc
     4621 tcggtggggc ggggacgccg gtactgatcg ccgggcccga cgggacggtc cgtgccacgg
     4681 tgaccgccgg ctgacgtgct ggccgaactt cgctgtaacc ggcggtaatt aggcgagatt
     4741 tcaaccttgc cgccgtctgc cccagccgca tcaatggaac cgtcagttcc gacggaccgt
     4801 caggttcggc tctcggcagt gtgtccgcat ccacgtgccg agcggtcccc ccacacggaa
     4861 agggaaccgt aatcccatga gatgcaagcg aatcggagcg ggcgcggccc tggcggccgg
     4921 tgccctcgcg gtcaccgggc tcgccttcgc ccccgccgca ctcgccgtca cccctcagac
     4981 ggcgacgatc agcgccgact gcggcacctt cggcagtggc gaggccacgc tcacggccac
     5041 gcaggacggc accgccgcca ccgtcaccgt caagtcgtcc gcgatcaccg cgccgatcgg
     5101 cctcggcgag gactcgatcg cgtccaccct caccctggtg aagaccggcg gcggcaccgt
     5161 cgacttcacc ggcacggaga acccggcgat ggccgccggc gcccccgtcg aggtcggccc
     5221 cctcagcggc accgtggctt ccggcgacag cctggaggcc ttcggcggct cgctgaagat
     5281 gaccgtcttc ggcatcacca tcacctgcac ggcgaccggg ccgcagtcgc cgggcccgtt
     5341 cgtgttcgac tgatcccggc cgggccgggc gcgacctaca gcgcgtccgg cccgcgctcg
     5401 cccgtccgca cccgcacgac cgtgtccacg ggcagcgccc acaccttgcc gtcgccgatc
     5461 ttgccggtgt gcgcggcctt cacgaccgcg tcgatgacgg cctcggcgtc cgcgtcctcg
     5521 acgacgacct cgatccggac cttcggcacc aggtcgacct ggtactcggc gccgcggtac
     5581 acctcggtgt ggccgcgctg ccgtccgtag ccgctggcct cgctcacggt caggccctgc
     5641 acgccgagtt cctgcaaggc gttcttgatc tcgtcgaggc ggtacggctt gacgatcgcg
     5701 gtgatgagct tcatgcctgg ggggtgacct tctgggcgga ggagacgacg gaggaggaga
     5761 ccggggcgcc gtggcccagg accccgtgat cgtaggccgt ctcggcgtgc accgtaaggt
     5821 ccaggcccgt ctgctcctgc tcctcgctcg cgcggaagcc catcgtggcg tcgatcagct
     5881 tgccgatccc gtacgtcaca ccgaacgcgt acaccgccac cacgaccacg gccagcagct
     5941 gcttgccgag ctggccgagg ccgccgccgt agaggaggcc ctcggcgccg cccgtcatcg
     6001 actccacggc gaagacgccg atgaggagcg tgccgatgac accgccgacc aggtggacgc
     6061 cgacgacgtc gagggagtcg tcgtagttca gcttgaactt ccagctcacg gcgtaactgc
     6121 agacggcacc ggcggtgagg ccgacgacca gggcgccgag cagggacacc gaaccgcagg
     6181 acggggtgat ggcgaccagg cccgcgaccg cgccggacgc ggcgcccagg gtggtggggt
     6241 ggccgtcgcg cttctgctcg acgaagagcc agccgagcag gccggtgcag cccgcggcga
     6301 gggtgttgag gaacgcggcg gccgcgaggc cgttggcgcc gagggccgag ccggcgttga
     6361 agccgaacca gccgaaccag agcagaccgg cgcccagcat caccatgggc aggttgtgcg
     6421 ggcgcatggc gtccttcttg aagcccagtc gcgggcccag gaccaggcac aacgcgagcc
     6481 ccgaggcacc ggagacgatc tccacgggca gtccgccggc gaagtcgagg gcaccgagcc
     6541 ggtcgaggat ccagccgccc gggccccaga cccagtgcgc gaccggaacg tatacgagca
     6601 gcgcccacac cggcacgaag accagccacg ccccgaactt cgcccggtcg gcgaccgcgc
     6661 cgctgaccag ggcggcggtg atgatcgcga aggtgagctg gaaggtggcg aacaggaggg
     6721 tggggaccgt gccctggacg ctgtccggcc cgaggccgct catgccggcg tggtcgagcc
     6781 cgccgatgag cccgcccgcg gcgtcctcgc cgaaggcgag ggagtagccg gcggccagcc
     6841 acaccaccgt caccagggcg atcgacacga agctcatcat cagcatgttg agcacgctct
     6901 tcgtgcggac catgccgccg tagaacaggg ccaggcccgg ggtcatcagc aggacgaggg
     6961 cggtggcggc gagcagccag gcggtgtcgc cggtgtcggc gcttgcggcg gccagaggca
     7021 cggtgtctcc aacgaggtgg ggctccgggg gctcgtcaga ggttcaccgg cctgcgtttc
     7081 cggttgcgta cgagtgtgtt tccgtgacgt ttcgttgcct gcgggtttcc ggaacctcac
     7141 gggccgggcg gcgttcgggc gcctgtgcgg cggggctctg tggatcaggg agaatgggcg
     7201 ccatgagcgt tcgtacccag tcatccgaag agccggccga agctgtccac cgggctggct
     7261 tcgcctgctt cgtgggccgt cccaacgcgg gcaagtccac cctcacgaat gctctggtcg
     7321 gccagaaggt ggcgatcacg gcgaaccagc cgcagacgac gcggcacacc gtgcggggca
     7381 tcgtgcaccg cccggacgcc cagctgatcc tggtcgacac cccggggctg cacaagccgc
     7441 gcacgctgct gggcgagcgg ctgaacgacg tcgtgcgcac gacgtgggcc gaggtggacg
     7501 tgatcggctt ctgcctgccg gcgaacgaga agctcggccc cggcgaccgc ttcatcgcga
     7561 aggaactcgc gtccatcaag aagacgccga agatcgcgat cgtcacgaag acggacctgg
     7621 tggacggcaa ggcgctcgcc gagcagctca tcgcgatcga ccagctcggc aaggagctgg
     7681 gcttcgagtg ggcggagatc gtcccggtgt cggcggtcgg cgacaagcag gtgggcctgc
     7741 tggccgacct gatcgtcccc ctcctgccgg agggcccggc gctctacccc gagggcgacc
     7801 tgaccgacga gcccgagcag gtcatgatcg cggagctgat ccgggaggcc gcgctggagg
     7861 gcgtccgcga cgagctcccg cactccatcg ccgtcgtcgt cgaggagatg ctcccccgcg
     7921 aggaccgccc cgccgacaag cccctgctcg acatccacgc cttcgtctac atcgagcgcc
     7981 ccagccagaa gggcatcatc atcggcccca agggcaagcg tctgaaggag gtcggcatca
     8041 agtcccgcaa acagatcgag gcactcctcg ggacaccggt gttcctggac ctccacgtga
     8101 aggtcgcgaa ggactggcag cgggacccga ggcagctgcg caagctgggg ttctgaggag
     8161 ccggcttccc gtgccggtgg gacgtcacgc ggacggtcac ccggcgccgc ccttcaggcc
     8221 ggccgtgcgc ggcacgcgga gatccccggt ctgctgagcg cggaggagcg accggtagtg
     8281 ctcactgctg tcgaggagct ccccatggct gcccgtggcg acgacccggc cggcgtcgag
     8341 gacgacgatc aggtccgcgg cgtggatggt ggacatgcgg tgcgcgatca cgagcaacgt
     8401 gcactcccgc gtggcttccc gcatcgacct gcgcagcgcc gcctcgctga ccgcgtccag
     8461 atgggcggtc ggctcgtcca gcaggagcag acgcggccgg gccagcagag cacgggcgat
     8521 ggcgatccgc tggcgctcac caccggagag cgccatgccg tgctcaccgg cgtcggtgtc
     8581 caggccccgc ggcagacggg tgatcaggtc cgacaggtgc gccagctcga ccacccggtc
     8641 gagctcctcc ggttcagcgt ccgggacggc gtacatcagg ttctcccgca gtgtgccgta
     8701 cagcaccggg gcatgctgtt ccaccaggcc gatccgggcc cggtgttcgg cccggccgct
     8761 cgcccgtatg tcacggccct cggcaaggat gtggccgctg tccgggtcgt agaaccgctc
     8821 gatcagcgcg aacacggtgg actttccgac tcccgagctg ccgatcaggg ccacgtggga
     8881 gtgctccggt gcctcgaagg tcacgccgcg caggacggga cggcgcggtt cgtagccgaa
     8941 ccacacgtca cggaactcca gcgcgggcgc ccgtgaccgg ccgccgctgc cccccgccgg
     9001 gcgggacacc ggagctccgg ctcccgacac ggcgtcctgc tccgtgggca gctccagcac
     9061 ttccgtgacc ctgcggtacg cgcccacgcc ctgctccatg gtgctgaggg actggaacag
     9121 catgccgatc ggctccacca gatagatcat gtacagcagg aaggcggcga gatcggcgat
     9181 cgacccctgc cggtcggcga cccgcatgcc gccgatgagc agcacgacga cgaaggatcc
     9241 tttgacggcc agctggatcg ccggtgccac cacggcgtcg agcttcgcca tccgcacact
     9301 tcccgcgtac gccgatcggg cgccatccgc gatgcggtcg gtttcgcgct gctcggcgcg
     9361 gctggcccgg accgtgcgga tggcaccgag cgcgcgctcc agatcagcgg tcatcgcacc
     9421 cgtcgcccgc tgcgtggaca gcgacgccac ctcgatgccg tgcagcaccg agacgacgat
     9481 catggtggcg atcgccacca tgcccagcac gacgaggaac atcaaccagt cgagccagat
     9541 catcagcgcc acgacaccga tcagcccgat gacaccggtg atcgcttcgg tgaagccctc
     9601 cgcgacgagc agccgcaagg tcgtgctgtc ggtgctggtg cgcgagatca gatcgcctat
     9661 gcggtggcgg tcgtagacgg ccatgggcaa ccgcagcacg tgcttgatca ggccgagccg
     9721 gatccccagg acgatccctt cgcccgtccg ggccaggacg aactgggcga ggccctgcac
     9781 cagtgcctgg gcgaggaaga ggacgacgag cagcaccagg gcggtcccga tcgcgctgcc
     9841 ggaggtggtc gactcgatca cctgcttgac cagcagcggt tgggccaggc tcagagcgga
     9901 ggctcccagt gtcagcagga cggcgagagc cacccaccgc cggtggccgt gcagcaggcg
     9961 caggaagtcc cgcggcgcgg tccggctccg ctcgtcggtc tcacccgtcg ctcggggctt
    10021 catggatcac ggcctcacgg cggacggaac caggaacgca gggcacggtg aacagggggc
    10081 ggaagtagtc gggcgggtgc tcctctccca ccggcacccc ctccgcctcc acccaggcgt
    10141 gcgcaccgaa gggcggcagg cgccgcgcgc ccacgcacca ggtgggccac tggccgtgca
    10201 ggcggcacag caggaccgtg gcgagcgacc ggggcaggca cccttcccgc cccccgcacg
    10261 cgaggctgac cgcgaccacg gagtcccggg cggcccgggt ctgcccgagg gtggccggac
    10321 gggcgccccg gcgcagccac tccagcgcgg cccgtatgcg ccgggggcgc tgacgggcca
    10381 ggagccgcgc tgctcccacg gcgagccgga ccgggatccg gcgccgcaga ggaaccgagc
    10441 gcgggtcgtg gaagatcacc tccggtgagg tcatcgccgc tccctccccg cacgccggcc
    10501 gcgcaggtgc ggccatcggc cgcccatccg ccgccgcacc agcccgacgg gccgggccgt
    10561 cggagctcgg gcgccctctc ccggcccgtc gctgtccgct tcgcccaggc ccgccgagta
    10621 cagtccgccg accaggtccc ggacgtcccg ccgcgccgtg ccgatgtcca ccgcgtactc
    10681 cgcgctgagc gtctgcgcgg cgtcgtcttc gctgccgccc gccagcaacg tgtgcaaggc
    10741 gacggcggcg ctgggattga gcgtccagta ctggttgcgg tcctcgtcga ggatcgcgat
    10801 cccgtagtcg gtctcggccg tgaacacacc ctcacgcagc ttgaacgcca tcggccgtct
    10861 ccattcagcc cggaacagcg gtggtggcgg tttccagcgt gcgcagccac atctcgcaca
    10921 ccacggtctg gtacagcgcg tcgaaaggca ggctcggggg cagcggccgg ccgcacgtct
    10981 cgcgcagcac cttcgcgtcg atcagaccca accgagccag ccgggagtcc tcgcacaggg
    11041 ccagcaactc ggcacgctgt tcccgcatcc cgacctccgc ctcgtaggaa ccctcgtcct
    11101 tggtgtgacg ggtcaggctc tcgtcgggaa cgatgccgcg catcgcctcg acgatgagcg
    11161 gcttgtactg ccagggggtg atcctgtcct gcggccgcac cgccaggccc gcttcgacca
    11221 cccggtcgtc gtagtagggg gcggcgaggg tgagcccggc gcggctggcc atctggccca
    11281 cctgccggac catgcgggag ttgttcccca tggcttccag ctcgatgtgc tgcccgcgcc
    11341 tctcggccag tggttcggcg gtacgcgccg cggtgcggat cagttcgcgt acggccgcga
    11401 cggcgtccgg cgtcgcccat ggagggagcc gtggcggcgt cccccagtcc agcgcgggcg
    11461 tctccaaggg gggcggtacg gcggtgagca ggtcgccggc tcggccgagc cacgtccggt
    11521 aggagctgtt gtcccacaac tgccgcagtg cttcccggta cggccacggg ccctgggcgg
    11581 cgaagccgcg caggcgctgc cacgcgatcc tggggtgggt ccgtgccagc gtgtgcagat
    11641 gcgccggcga gccggagagc aactcgtccc cgccgaagcc cgtcaggtgt atgcgggagc
    11701 cctgtgccgc agcaagccgc ggaatgagca gacagcggct gggatgcatc atcgccgggc
    11761 acggctcgtc gaagcgctcg tccacgtccc ggaggccctc gtacaccatc ggcaactggt
    11821 ctccggcgat gacgtggtga ccgacgtcgc ccagtctcgc gaccgtccgg cgcgcccagg
    11881 tcacgtcgtc gcacaggggg tcgagaccgt cggcggtgta ggcgatgacc ttcgccgtgc
    11941 cgcgtgcggc cagagcgcac accgaggtcg agtccaggcc gcccagatcg cagctcacca
    12001 cgtcccggcc ccggacgcgg acctccaccg ccgccgacag tgccttccgc aacgccgacg
    12061 cgccctcggc catcggcacc accggctcgg gaggcgccca ccacgcgacg ggccgtcccc
    12121 ggccgtcggc gtcgagcgcc aggtagcggc cgatccccag ggcgcccaca ccacgccaca
    12181 ccggttcgcc ggccagcggg tgcggcgcgc acggattcag caggcgggcc gccagccgct
    12241 gctcgtcgac ctccgcgtcg agcagagcgg ccaagacgtc ggcccggtcc gcggccacgg
    12301 tggtgtcctc gagcctggcg tggaacaccc gccgaaagcc ggtgacgctc ccctggacac
    12361 gcacccgtcc ggcgaccgaa gcgaccagat gccaactccc ggccaggccg cgggccagac
    12421 cgtccaggtc gctgatcgtc cggatccggt cggccgccgg ggtgagccgg tcggcggtga
    12481 cggcgtgttc accgacgact gcgatcttcg tccggcccgc ctcgccgacg gccatggcac
    12541 cgggagacca gtggccgagc agccacggcc gtcccgacgg gtggctgacc tcctggacct
    12601 tccgggtgcg aagtgcggcg gacacccggg ccgccgaagc acagtccgga aggacgacga
    12661 accagcccgg accctcgccg gaaccaggaa aatcgaccat gccggtccct tcctgtaccc
    12721 cgagccctga agcgatcaag agatgtgggc ggcaggactg acgccctgcc acccctcgga
    12781 gatcccgcac cggcggaaca accggcggat cagaagaacc tcctccggaa gaaccagaac
    12841 ctctccggcc cgtccctgaa gcccagaccg gtcttgcgga aggagccgac cgcagtcagc
    12901 gtcggacgct cgtaggtgcg catgtcgttg cacctcctga actgcgcgcg tcgctatcgg
    12961 ttgtctcttc caccatgaca ccaaatgggg tgattggcca aaaagtctgg tttgaccaaa
    13021 gagccagata acgttactga ttcaaccttt aggacttctc aggggcattg ggtcgtcgcc
    13081 aggctcgccc acaccgcgtt gccccccgtg aggggtgagc gggtgactcc ccagctgtcg
    13141 gctatctccc gtacgagcag caggccacgg ccgccctcgt cgtcgagggc ggggcggcag
    13201 tcggggatgc cgcggcccgt gaggtcgccg tcgtgcacct ccagccggaa gcgttccgcc
    13261 gtcatccggc ccacgccgca caggatccgc tcgccgggcg tgtgcagaac ggcgttggtc
    13321 accagctcgg acaccaccag gacggcgttc gcgcacgcct cgtcgggcac ctgccaggag
    13381 tccagccgcg cctgcgtggc atgacgggcg actctgacgc tggtccggtg ggacggcagc
    13441 tccagccagt gggtgcggcc cgggcgcacc gcgtccagga accggggagt ggaagtcgtg
    13501 tggggggaca cggcattcgc cttccgtggg ggtgggcgca gtcaaggaag gggcgaggcg
    13561 cgaaacggac cgcccggaag gggacttggg gattccggcg ccctgttcac acaagtaact
    13621 atgctcgtag agcagttcac gctgcaacca tctgcctgat aatttcagaa ggaaggtatc
    13681 gctgctccgg gccgcttggc ggacgatcaa gtccctgtca ggcttgcacc ggtgacgacc
    13741 cctcaggagg cacgggcgtg aacgacgcgc gatcaggcac cggcgccggc gcgcccaccg
    13801 ttctccgcat gatcctggga cgccgcctcc aggaggcccg gcagaccgcg ggcctgtccc
    13861 tcgacgacgc ggccaaggcc ctgcgcgtca cgccgctgac catccgccgc ctggagaagg
    13921 ccgaggtcgg cctgaagatc ctctacgtcg agaagctgct ccagacctac ggggctgagc
    13981 agcaggagat cgacgagttc gtcagtctgg ccgagcgggc caacgagccc ggctggtggc
    14041 acccgtaccg cgatgtgatg ccgtcctggt tcaccgccta cgtgagcctg gagaccggcg
    14101 cgagaacact gcgcacctat gagccgcagt acgtcacggg actgctccag acacccgggt
    14161 acgcccgtgc cgtgctgcgc ggcggcttcc cgaacgacaa cgacgaggac ctccagcggc
    14221 gcgtggagct gcggctgcgc cgccagagcc tgctcacgaa gccggacgcg cccacgctgt
    14281 gggtggtgat ggaggaggcc gtgctgcacc gggtggtggg cggccccgag gtgatgcgcg
    14341 agcagatcga ccggctcctg gaggcgtccg agctggagca cgtcagcgtc gacatcgtgc
    14401 cgttcacggc gggcgcccac gtcggggcgt gcgcgccctt cacctacttc cggttcgagg
    14461 agcgggagct gcccgacatt gtctacagcg agatcctctc cgcgtccgtc tacctcgacc
    14521 agcgcgccga cgtcgtggcc catctggagg cccacaaccg gctgtcgctg aagacctcgt
    14581 cagcggacag caaggcgctg ttgaaccgca tgcggaagga gtactcatga ccatcgccga
    14641 gggcgccgtg tacaacggga tgcccgcgtc ggacctcggg gaacagggct gggaacgtcc
    14701 gtggagcggc cccaacgggg gccagtgcgt ggagaccaag caactggccg acggccgcgt
    14761 ggcggttcgg cagtcggccg atcccgccgg tccggcgctg atctacacgc ccgaggagat
    14821 caccgcgttc gtcgcgggcg tcaagcaggg cctcgccgac catctcacgg ccctctgaac
    14881 ccccgcgatc cccacaaccc ccaccgagcc ggacccgcac caccaccccc caccgagagg
    14941 cacggcatga cccactcgca cgcgtcacgg gacatcgaca ccagcaggcc gcactccgcc
    15001 cgcatgtacg actactacct gggcggcaag gaccacttcg aggtggacaa gcaggcggcc
    15061 gagcgggtcg ccgaggccta ccccgccatc ttcgtctgcg cccgcgagaa ccgcgccttc
    15121 atgcaccggg ccacccgcgt cctcgcccgc gagcacggca tccgccagtg gctggacatc
    15181 ggcaccggca tccccaccga gcccaacctg caccaggtgg cccagtccgt ggtccccgac
    15241 gcccgcgtgg tctacgccga caacgacccc ctcgtcctca agtacgccga gcgcctgatg
    15301 cgcagcacgg ccgagggccg tacgacgtac atagaggcgg acgtcaacga cccccaggcg
    15361 ctgctgaccg cacccgaact ggccgaggtc ctcgacctga gccgcccggt cgcgctctcc
    15421 ctcaacgcgc tgatgcactt cgtcaccgac gcccaggacc cgtacggcat cgtgcgccgg
    15481 ctgctggacg tcctgccctc gggcagcgcc ctggcgctga gccactgcac gcccgacttc
    15541 gacccgtcga cctggcagaa ggtcaccgag atctacacct cggccgggac gccggtgcag
    15601 ttccgctccc gggcggacgt cacccgcttc ttcgacggcc tggagctgct cgaccccggt
    15661 gtcaccgtcg gccaccgctg gcggcccgac gccaccgacg gcgacgcccc gacggacgcc
    15721 gaggtcagcc tgtggaccgg ggtgggcgtc aaaccgtagt tccctgggcc cgcagcacct
    15781 cccggtacca gcggtacgac gacttcgggg tccgctccag ggtctcgaag tcgacgtgga
    15841 ccaggccgaa gcggcgggcg tagccctccg cccactcgaa gttgtcgagc agggaccaca
    15901 cgaagtagcc gcgtacgtcg acgcccgcct ccagcgcccg gtgcagggcc cggatgtggc
    15961 cgtccagata ggcgatgcgg tcctggtcgt cgacgtccgg gtacgagcag ccgttctcgg
    16021 tgatgacgac gggcgggagc cggtcgccgt agcggtcgtg gaaggtggtg aggagctcgg
    16081 tcaggccctc gggcacgacc ggccagccga agtcggtgac cgggtggccc gtgatctccc
    16141 gtacggagaa ggggagttcg gcgggcatgg cgacgccgcc gaaggtgatg tcggtgccct
    16201 gcggggcgcc cacccgcgtc ggcgcgtagt agttgacgcc gtaccagtcg accggctcgg
    16261 cgatcacctt caggtcggcc gcgacgtccc cgggcatcag ctcgccgatg ccgtccgggt
    16321 agcggcccag cagcagcggg tccgcgaaca gtcggttcag cagcacgtcg tagaactcgg
    16381 ccgcctccgc gtccgccgcc tcggtcgacg cggcccaggt cgggccgtgc gagttggcga
    16441 tgccgatgtc cgtgacgccc gaggcgcgca gggcccggac ggccaggccg tgggccagca
    16501 gctggtggtg ggcggccggg agcgcgtcga acagcagctg cctgcccggc gcgtgcacgc
    16561 ccagggcgtg acccagcagg gtgtgttcgg cgggctcgtt gagggtgatc cacttcgtca
    16621 cccggtctcc caggcggccg gcgaccaggg ccgcgtactc ggcgaaacgc gccgccgtgt
    16681 cccgctccag ccagtccagg tccgtcggca ggtcccagtg gaacagggtc ggcaccgggc
    16741 ggatcccggc cgcgcacagg tcgtccacca gccggtcgta gaagtccagg cccttctcgg
    16801 agcgcacgcg cggccaggac accgagaagc ggtacgcgtt cacgccgagg ccggccagca
    16861 gtgccacgtc ctcgcggtgg cggtggtagt ggtcgcaggc caccaccgcc gtcgagccgt
    16921 ccttcacccg gcccggctcg gccgtgaagg cgtcccacac ggagggctcg cgctcgtccg
    16981 ccgcgccctc gatctggtgc gccgaggtcg acacgcccca gaggaagccg gccgggaagc
    17041 gggggatcgg attgcctgcg tcagtcgcca tgcgctggat catccgtacc gccggtaaca
    17101 gaagtcaaca ggccgccgcg gagcacctgt tgcccccgcc tgtcacgccc cctccttcag
    17161 cacccgggag atcagcttcc gctgctcctc ggtcagccgg gggtccgcgc agtacaccgt
    17221 cttgccgtcc accgtgatct ggtagccgaa gccgtccgga acgccgatcg gcggagtgct
    17281 ccgtccggcg gcgaacgcct tctcggccag ggcgtgccat tcgggggcat cggggcggcc
    17341 ggaggtgtcc acctcggcat gccgttcgat gcccgcgaac ccgcccgtgc gcctcacctg
    17401 aatccgcatg gcacctgtct agtacggaac tacagggtcc gcaccccgac ctgctcccag
    17461 gccttcgaca cggcgtccag ctcctccccg tcgccgaacc gctcccgcgc ggccttgacg
    17521 gtgagcgtgg cgaagtcggc gaacatcgcc tgctgcttca gctcgccgcc ggtcagcacg
    17581 tcgtaccaga cctgtcccgc gcgttcccag gcgtggccgc cgagggccgt ggccgccagg
    17641 tagaaggcgt ggttcgggat gcccgagttg atgtggacac cgccgttgtc gcggccggtg
    17701 cggacgaagt cgtccatcgt ggccggctgc gggtccttgc ccaggacgtc gtcgtcgtac
    17761 gccgtgcccg gctccttcat ggagcgcagc gccttgcccg tcacccgtgg ggcgagcagg
    17821 cccgcgccga tcagccagtc cgcctcggcg gcggtctggc ccagcgtgta ctgcttgatg
    17881 agcgagccga agacgtccga cagggactcg ttcagcgcgc cgggctgacc gaagtaggtg
    17941 aggttggccg tgtactgggt gacgccgtgg accagttcgt ggccgatgac gtcgatcggg
    18001 atggtgaagt cgaggaagat ctcgccgtcc ccgtcgccga agaccatctg ctcgccgttc
    18061 cagaaggcgt tgttgtagtc gcggtcgtag tgcacggtcg cgttcagggg caggccgccg
    18121 ccgtcgatgg agtcgcgctg gtacgcccgc cagagcagct cgaaggtggc gccgaggccc
    18181 gcgtaggcgc ggttgacggt ggcgtccttg ccgggcttgt cgccctcgcc gcggaccttg
    18241 tggccgggca ggtcggtgcc gtgccgggcg tcgtggatgg tccgctgcgg cttgccgtcg
    18301 gcgaccccgg tgacggcggt cgcgccgatg accgtggtga ggcggcgctg ggtgcgctcg
    18361 aaggcgtcgc gctgcagcgt gcggcgggcg ggcccggcga gcgcggggtc ctcggcctgg
    18421 gcgagcttgt cgaggacatg cggtggaacg atggtgcaga agacgggctc gaagcccccg
    18481 tgagtcgtca tgcccggcac ccttgcactg cgtgacggag ctgtcactag tcgccaccat
    18541 gattggtgaa ataccgggac aagggccttc accctccgtg gcgaagtggt atagcgcact
    18601 ttttgtcccg tatgtgcgcc cggtcccgca tactgatacg gacccgcgca cccggagggc
    18661 ctcggctagc atgctgcgca tcatgcgttt cgggctgctt ctccttagct gccgcggcga
    18721 gggcctgtag tcgaggccga ctccctcccc gcggagcttg gtgctgcgtc gtcggccgtc
    18781 cttccggaca ctctgaggag cccccgcatc atggcgaacc gccagcagcc cagttccatg
    18841 ccgatccaca agtacggccg ctacgagcag gtcgacatcc cggaccgcac ctggccgaac
    18901 aaccgcatca ccgccgcccc ccgctggctc tccaccgacc tgcgtgacgg caaccaggcc
    18961 ctgatcgacc ccatgtcgcc cgcccgcaag cgcgcgatgt tcgacctgct ggtcaagatg
    19021 ggctacaagg agatcgaggt cggcttcccg gcctccggcc agaccgactt cgacttcgtg
    19081 cgctccatca tcgaagagcc cggggccatc cccgacgacg tcaccatctc cgtactgacc
    19141 caggcccgcg aggacctgat cgagcgcacg gtggagtccc tgaagggcgc caagcgcgcg
    19201 accgtccacc tctacaacgc caccgccccc gtcttccgcc gggtcgtctt ccggggctcc
    19261 aaggacgaca tcaagcagat cgccgtcgac ggcacgcggc tggtcatgga gtacgcggag
    19321 aagctgctgg gcccggagac ggagttcggc taccagtact cgccggagat cttcaccgac
    19381 accgagctgg acttcgcgct ggaggtctgc gaggcggtca tggacgtctg gcagcccggc
    19441 ccgggccgcg agatcatcct caacctgccc gccacggtgg agcgttcgac cccgtcgacc
    19501 cacgcggacc gcttcgagtg gatgggccgc aacctctccc gccgcgagca cgtctgcctg
    19561 tccgtccacc cccacaacga ccgcggcacg gccgtcgccg cagccgagct ggccctgatg
    19621 gccggtgccg accgcgtcga gggctgcctg ttcggccagg gcgagcgcac cggcaacgtc
    19681 gacctggtca ccctgggcat gaacctcttc tcgcagggcg tcgacccgca gatcgacttc
    19741 tccgacatcg acgagatccg tcgcacgtgg gagtactgca accagatgga ggtccacccg
    19801 cgccacccgt acgtgggcga cctggtctac acgtccttct ccggctccca ccaggacgcc
    19861 atcaagaagg gcttcgacgc catggaggcc gacgcgaagg ccaagggcgt caccgtcgac
    19921 gacatcgagt gggccgtccc gtacctgccg atcgacccca aggacgtcgg ccgctcctac
    19981 gaggcggtca tccgggtcaa ctcgcagtcc ggcaagggcg gcatcgcgta cgtcctgaag
    20041 aacgaccaca agctggaact gccccgccgg atgcagatcg agttctcgaa gatcatccag
    20101 gcgaagacgg acgccgaggg cggcgaggtc acgccgaagg acatctgggc cgtcttccag
    20161 gacgagtacc tgcccaaccc cgagaacccg tggggccgga tccaggtcaa gaacaaccag
    20221 tcgacgaccg acaccgacgg cgtggacacg ctgacggtgg aggccacggt cgacggccag
    20281 gacaccgtcc tgtccggttc cggcaacggc ccgatctcgg ccttcttcga cgcgctccag
    20341 tccgtcggca tcgacgtacg cctgctggac taccaggagc acacgatgag cgagggcgcc
    20401 tccgcgcagg ccgcctccta catcgagtgc gcgatcgacg acaaggtcct gtgggggatc
    20461 ggaatcgacg cgaacaccac gcgggcctcg ctgaaggcgg tcgtctcggc cgtcaaccgg
    20521 gcgacgcgct gacctgtccc gacgagggtt caggggctcc gtccgccgtt gtccggcggg
    20581 cggagccccg tcgcataccg gccaatccct gtgagggtca cggaaaggtc tcctccgggg
    20641 tactgactcc tcctcacgga tgtggctaac atcacgcaag cgcggcgacg ctgccgtgcg
    20701 gcgtgacgga ggtgcgacgt gctgccagga cggggacgaa acggccatgc cgccaggttt
    20761 tcgagcatcc tgggcacccg taccgcgtgg acgcccgccg gtgacgggga gttcttctgc
    20821 cccggctgcg gcggcgaccg caactaccag cggctgaccg gacaacgccg cttcaccctg
    20881 ctcggcctgc ccgtgctgcc gcgcggtgag accggcccgg tcgtggagtg cgccgcctgc
    20941 cgccgccact tcggcacgga cgtcctcgac catccgacca ccacccgctt ctccgcgatg
    21001 ctccgcgacg ccgtgcacac cgtcgccctc gccgtgctgg ccgcgggcgg cgccggttcc
    21061 cgtccggcgc tggaggccgc ggtgctcgcc gtgcgcgcgg ccggcttcga cgactgcacg
    21121 gaggaacagc tggccgccct cgtggaggcg ctggaggcgg acaccggccg gatcaccggg
    21181 gagccctgcg gtgcggggct ggccatagag ctgcacgagg cgctggaccc gctcgccccg
    21241 cacctcgcca cggtcggccg cgaatcgatc ctgctccagg gggcccgtat cgccctggcg
    21301 gacgggccgt acacgcccgc cgagcgggac gtgctcgcga cggtgggggc ggcgctcacc
    21361 atctgctcgg acgacgtgac acgggtgctg gcggaggcgg cacggacgcc gtcgtagggc
    21421 agcgcccctg ccgggcactc cccggcgtcg ctccccgggc gttactcccc ggggagtaat
    21481 ccgccgcccg taccgccctc cgcagtaacc cccgactcgg cctcgggtcc gacgcatcgg
    21541 cccccgcgcg ccgggagtct ggagaccgtt ccagacaccc ggaccggagg gagcccgaac
    21601 agtgggggac acaaggaaaa ccgcacggcg gcgaaccgtg ccctgggtgg tggtcgggct
    21661 gtggctcgcc gccctcgtgc tggtcgggcc gctcgccggg aagttcgccg gcatccagca
    21721 gaaccgcgcc gtcgactacc tgcccgacag cgccgactcc acgcaggtcg cgcggatcca
    21781 ggaccggctg ccgggaggcg agtccaccga cctggtgctc gtgtaccacc gggacggcgg
    21841 tctgaccgac gccgaccggc gcacggccgc cgagcaggtc gccgaggtgc gcggcgccta
    21901 cgacctgacc ggcgagccgc acggcgtgcc gtccgaggac ggcaccaccc tgatgtaccc
    21961 ggtgtccagc acccagcccg gccaggacga ggaggcccgg aacgccttcg tggacggcgt
    22021 gcgggagatc gccgagggca gcggcgggct gagcgtcgag gtcggcgggc ccggggcgtt
    22081 gaacaccgac atgagcaagg tgttcgagac gatcgacggc accctgctct tggccacgct
    22141 cgccgtagtc accgtcctgc tgatcctgat ctaccgcagc ccgttcctgt ggctggtgcc
    22201 gctcgccgtc gcgggcgtcg ccgccgccgt gtcgatggcc gccgggtacg ggctccacga
    22261 actgttcgac gtcaccgtca ccggccagag cggcggcgtg atgaccgtgc tcgtcctcgg
    22321 cgccggcacc gactacgcgc tgctgctcat ctcccgctac cgcgaggaac tgcggcgcca
    22381 cgagcggccg tacgacgcca tgagcgccgc cctgcgcggc tgcggaccgg cgatcctcgc
    22441 ctcctccggg accgtcgggg ccgggctgct gtgcctgctc gccgccgacc tcaacagcag
    22501 cagcggcatg ggaccggtcg gcatggtcgg ggtgctcgcc gcgctggtcg ccatgacgac
    22561 cctgctgccc gccgtgctgg tgctgctcgg gcggcgggtc ttctggccgc tgatccccgc
    22621 gttcggcagc gagcctaggg cgcgccggtc gctgttcgcc gcgatgggga cctcggcgac
    22681 gcgcaggccc gtcaccgtgc
//
