LOCUS       NZ_LT963352            21086 bp    DNA     linear   CON 13-FEB-2024
DEFINITION  Streptomyces chartreusis NRRL 3882 isolate NRRL3882 chromosome I.
ACCESSION   NZ_LT963352
VERSION     NZ_LT963352.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces chartreusis NRRL 3882
  ORGANISM  Streptomyces chartreusis NRRL 3882
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wibberg,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2017) CEBITEC, Genome Research of Industrial
            Microorganisms (GRIM), Universitaetsstrasse 27, 33615, NRW, Germany
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 02:03:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,073
            CDSs (total)                      :: 7,984
            Genes (coding)                    :: 7,779
            CDSs (with protein)               :: 7,779
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 205
            CDSs (without protein)            :: 205
            Pseudo Genes (ambiguous residues) :: 0 of 205
            Pseudo Genes (frameshifted)       :: 91 of 205
            Pseudo Genes (incomplete)         :: 161 of 205
            Pseudo Genes (internal stop)      :: 14 of 205
            Pseudo Genes (multiple problems)  :: 56 of 205
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:02:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3038255
            Orig. end                         :: 3059341
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT963352.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="15"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11086)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    119..134
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.29"
                     /tool="antismash"
     misc_feature    complement(286..301)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.46"
                     /tool="antismash"
     misc_feature    complement(307..325)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.03"
                     /tool="antismash"
     misc_feature    complement(315..330)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.61"
                     /tool="antismash"
     gene            361..1125
                     /locus_tag="SCNRRL3882_RS13395"
                     /old_locus_tag="SCNRRL3882_2650"
     CDS             361..1125
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="SCNRRL3882_RS13395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2650"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_010047568.1"
                     /transl_table=11
                     /translation="MSTDISSAENESGAPVRTARVPKYYRLKKHLLDMTETQAPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDIGYVTADDRLAGLLDITAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLVKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SLDRDGQPVEWVRSVYRGDRYKFVARLKRPQE"
     misc_feature    1183..1197
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.53"
                     /tool="antismash"
     gene            1268..1534
                     /locus_tag="SCNRRL3882_RS13400"
                     /old_locus_tag="SCNRRL3882_2651"
     CDS             1268..1534
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992859.1"
                     /locus_tag="SCNRRL3882_RS13400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2651"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_173937245.1"
                     /transl_table=11
                     /translation="MSQAPEASRGAMVTPMRVVIGLCLIAPFVAMLWVGSYAKTDPAFI
                     GIPFFYWYQMAWVLISTALTMIAYKLWQRDQRARSAAKGGASE"
     gene            1531..3159
                     /locus_tag="SCNRRL3882_RS13405"
                     /old_locus_tag="SCNRRL3882_2652"
     CDS             1531..3159
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="SCNRRL3882_RS13405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2652"
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_010047575.1"
                     /transl_table=11
                     /translation="MKDGVNGVALAVFIFFFLAVTVMGFLAARWRKAENEHSLDEWGLG
                     GRSFGTWITWFLLGGDLYTAYTFVAVPAAIYAAGAAGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGIGGG
                     ENTNWFIKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGG
                     FDDIFAKASDAFSQTNPATGAPRGALVPAEAGQWTYATLALGSALALFMYPHSITATLS
                     SKNREVIRRNTTILPLYSLMLGLLALLGFMAIAAGIKVQNGQLAIPQLFETMFPDWFAG
                     VAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPAQETKVSKLVSLLVKVGAL
                     AFVLTMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLAGWAVGMIYGTVAAY
                     GVASPTQKHFGGSSKEIPGIGEIGYIGLTAFVLNVVVTVVLTFVLKALKAPDGIDETKP
                     EDYTADAGDPGVQVELPPATAGTSH"
     gene            3233..3739
                     /locus_tag="SCNRRL3882_RS13410"
                     /old_locus_tag="SCNRRL3882_2653"
     CDS             3233..3739
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="SCNRRL3882_RS13410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2653"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_010047577.1"
                     /transl_table=11
                     /translation="MDILIRRVKPAEYDALGEITAQAYLKDGLLDFGESDGYLGELRDV
                     AKRAAAADVLVATQGEHLLGGVTFVPAGGPMADIARPSEAEIRMLAVAHEARGRGAGEA
                     LVRACVDRARATDGCVRVVLSTQRTMHSAHRIYERLGFVRTPERDWNPVPELGDITLLT
                     YELTL"
     misc_feature    3750..3764
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.7"
                     /tool="antismash"
     misc_feature    3781..3795
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    3789..3802
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     regulatory      3817..3899
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(3983..3994)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            4045..6402
                     /locus_tag="SCNRRL3882_RS13415"
                     /old_locus_tag="SCNRRL3882_2654"
     CDS             4045..6402
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378224.1"
                     /locus_tag="SCNRRL3882_RS13415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2654"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_010047579.1"
                     /transl_table=11
                     /translation="MTIAPADPVSAAEDEHDGPGAALLRTLTELTADLPDADPGRVAAA
                     ALRGRSARADASELRELATEAAAGLISEDPVYSRLAARLLTIGIRAEAASQGVTRFTES
                     VAVGHREGLIADRTAAFVRTHAARLDALIDTAADDRFGYFGLRTLHSRYLLRHPITRKV
                     VETPQYFMLRVAAGLAEDDTSRSVDEVAALYGLMSRLDYLPSSPTLFNSGTRHPQMSSC
                     YLLDSPKDELDSIYDRYHQVARLSKHAGGIGIAYSRIRARGSLIRGTNGHSNGIVPFLK
                     TLDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLELRDNTGEDARRTHNLNLAHWVPDE
                     FMRRVNADGQWSLFSPSDVPELVDLWGEEFDAAYRAAEAKGLARKTLPARELYGRMMRT
                     LAQTGNGWMTFKDAANRTANQTAEPGHVVHSSNLCTEILEVTGDGETAVCNLGSVNLGA
                     LVDRSGGDIDWERLDETVRTAVTFLDRVVDINFYPTEQAGRSNARWRPVGLGVMGLQDV
                     FFKLRLPFDSPEAKRLSTRIAERIMLAAYEASADLAERNGPLPAWEKTRTAKGVLHPDH
                     YDVQPTWPERWAALRERVAATGMRNSLLLAIAPTATIASIAGVYECIEPQVSNLFKRET
                     LSGEFLQVNSYLVEELKRLGAWDARTREALREANGSVQDFAWIPADVRALYRTAWEIPQ
                     RGLIDMAAARTPFLDQSQSLNLFMETPTIGKLSSMYAYAWKSGLKTTYYLRSRPATRIA
                     RAAQATVPVQATPDPEAVACSLENPESCEACQ"
     gene            6402..7409
                     /locus_tag="SCNRRL3882_RS13420"
                     /old_locus_tag="SCNRRL3882_2655"
     CDS             6402..7409
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657910.1"
                     /locus_tag="SCNRRL3882_RS13420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2655"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_010047584.1"
                     /transl_table=11
                     /translation="MTTQNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLHSD
                     VADLAKLSPAEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEEAV
                     HVQFYLTLLDTYLPDPEDRAAAFAAVENIPSIREKAGFCFKWMDSVEQLDRLETQADRR
                     RFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFDVV
                     DTVRKEEPELFDDQLRQQVTDMLREAVEAELQFARDLCGDGLPGMNTESMRQYLECVAD
                     QRLSRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDEDF"
     gene            7658..8620
                     /locus_tag="SCNRRL3882_RS13430"
                     /old_locus_tag="SCNRRL3882_2657"
     CDS             7658..8620
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437909.1"
                     /locus_tag="SCNRRL3882_RS13430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2657"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_010047588.1"
                     /transl_table=11
                     /translation="MLQNVAVVLLDGVNPFELGVVCEVFGTDRSDDGLPVYDFAVASAE
                     GPALRTNTGFSLHVEHGLERLETADLIAVPAGHCYESRDFPPELLDALRRGAGRGARVL
                     SVCSGVFVLAAAGLLDDRRCAVHWRHAQALARQYPRVAVEPDVLYVDEDPVITSAGTAA
                     GIDACLHLVRKEQGSEVANKIARRMVVPPHRDGGQAQYIERPLPHSEADTIGEVLAWME
                     RHLDEEVTVEQLAARAHMSPRTFARRFQQETGTTPYRWILRQRVLLAQRLLEATDETMD
                     AIAGRTGFGNSATLRHHFVRAVGTTPNAYRRTFRGPEAA"
     gene            complement(8634..10004)
                     /locus_tag="SCNRRL3882_RS13435"
                     /old_locus_tag="SCNRRL3882_2658"
     CDS             complement(8634..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326965.1"
                     /locus_tag="SCNRRL3882_RS13435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2658"
                     /product="cytochrome P450"
                     /protein_id="WP_010047589.1"
                     /sec_met_domain="p450 (E-value: 3.9e-69, bitscore: 232.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVKPEAPLAPELREPPRAGGGVPVLGHGWKLVRDPLAFMSR
                     LRDHGEVVRLKLGPKTVYAVTTPALTGALALSNDFIIAGPLWESLEGLLGKEGVATANG
                     PRHRRQRRTIQPAFRLDAIPAYGPIMEEEAHALTERWKPGETIDCTSESFRVAVRIAAR
                     CLLRGDYMDERAERLCVALATVFRGMYRRMVVPLGPLYKLPLPANREFNRALADLHLLV
                     DEIVAERRASGQKPDDLLTALLEATDENGDPIGEQEIHDQVVAILTPGSETVASTIMWL
                     LHMLAEHPEHADRVRDEVEAVAGGRPVAFEDVRGLRHTNNVVVEAMRLRPAVWILTRRA
                     VRDTELGGYRIPAGADIVYSPYAIQRDPKSYERNLEFDPDRWLPDRAKDIPKHAMSPFS
                     VGNRKCPSDHFSMAQLTLITAALATKYRFEQVVGSNDGTRVGITLRPHDLLLRPVAR"
     gene            complement(10001..11086)
                     /gene="cyc1"
                     /locus_tag="SCNRRL3882_RS13440"
                     /old_locus_tag="SCNRRL3882_2659"
     CDS             complement(10001..11086)
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992851.1"
                     /locus_tag="SCNRRL3882_RS13440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2659"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_029181723.1"
                     /sec_met_domain="T1TS (E-value: 3.7e-64, bitscore: 216.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHALSHGTTSTPTTIAVPPSLSLPVIEAAFPRQLHPYWPKCQEKT
                     RAWLLEKRLMPADKVEEYADGLCYTDLMAGYYIGASDEVMQAIADYSAWFFVWDDRHDR
                     DIVHGRPVAWRRLRDRLHSALDSPGEHLHHEDPLVAGFADSVLRLYAFLPGTWNLRFAR
                     HFHAVIDAYDREFYNRTHGIVPSVEEYLLLRRLTFAHWIWTDLLEPAAGCELPATVRKH
                     PAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHEGLTLEQAVVEVRRRVE
                     KCITEFLDVEQEALRFADALADGTVRGKELSAAVRACLSNMRNWFSSVYWFHHESGRYM
                     VDSWDDRSTPPYVNNEAAGEK"
     misc_feature    complement(10202..10204)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11382..12032)
                     /gene="def"
                     /locus_tag="SCNRRL3882_RS13445"
                     /old_locus_tag="SCNRRL3882_2660"
     CDS             complement(11382..12032)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="SCNRRL3882_RS13445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2660"
                     /product="peptide deformylase"
                     /protein_id="WP_010047593.1"
                     /transl_table=11
                     /translation="MAQQDTDQQRAGVLPVDDEGYVIDTEDCEEREAAWRERGTSRPIT
                     VVGNPVLHKECKDVTEFGDDLQQLVADMFASQRTAEGVGLAANQIGVDLKVFVYDCPDD
                     EGVRHTGVVCNPKLVELPAEKRRLDDSNEGCLSVPTAYAPLARPDYAEVTGQDEKGNPI
                     RVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYPVVAND"
     gene            complement(12165..13145)
                     /locus_tag="SCNRRL3882_RS13450"
                     /old_locus_tag="SCNRRL3882_2661"
     CDS             complement(12165..13145)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="SCNRRL3882_RS13450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2661"
                     /product="hypothetical protein"
                     /protein_id="WP_010047594.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRDTGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRVPGAANDSGEPVGMDLGSAAVRLSPEGEAEVVWGRRLDPARIEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTAAGHTYPVFDEIELWAPSPVPTWVVLLEAATESDRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGLAAPASLVRGLLDGWVADSPDSRDWRDLEEVC"
     gene            complement(13263..14600)
                     /locus_tag="SCNRRL3882_RS13455"
                     /old_locus_tag="SCNRRL3882_2662"
     CDS             complement(13263..14600)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016824676.1"
                     /locus_tag="SCNRRL3882_RS13455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2662"
                     /product="HD domain-containing protein"
                     /protein_id="WP_040904319.1"
                     /transl_table=11
                     /translation="MAPRRDRRRRPPAPDSPARRTCLQPAGSTPVSAYRPPPLFTLVHA
                     CAALLAAGSLAVTLHHGLEERRGALAFGVLVTVGELARRNGAQVREPAPLGAAAALSYA
                     LLGEAGGRATHHGPAQVVAVVLAASLLGSVPHVARGQGPTLDHLARRVLTVGFVAVCFQ
                     PPYNRGMFDDWGGPAYALLLLALLSLTALCDAVLAAALAHSRTGWPFGPVLRDELRAVC
                     GIGAAVIATGAVMALAVAVVGLWALPVFSVPLLLAQMSFRRYAAVRATYRQTIASLARA
                     TEVAGYTPAGHARRVAALSLAVGRDLGLTEPELAVLEYAALMHDIGQLSLVDPVPSGAT
                     AGLPAAEQRRIALLGGAVVRQTGVDEAVAVVVERQADPFAEQPLAARIVRAVNAYEEKS
                     REGGPGGPLTALEELRLATAGEYAPEVVESLARVLARSSLTMRLTG"
     gene            complement(14507..15838)
                     /locus_tag="SCNRRL3882_RS13460"
                     /old_locus_tag="SCNRRL3882_2663"
     CDS             complement(14507..15838)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072151.1"
                     /locus_tag="SCNRRL3882_RS13460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2663"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_010047597.1"
                     /transl_table=11
                     /translation="MDAVPVRARVYVACVVFAALLCLLPLPGVRTPWWAVLLLAALYAG
                     CERVARSRFVGISHPAGTFYPVLLAGAFLLPAPAAALVAVPGALLSHVEQRPVALRRVW
                     RAAQLVLGVWAAARVHRALGGRDAVLAGDVPYALGPAGAAVLAFCLVLAVLDGGILAVA
                     ERVPVRRAWRGLVARSLAPIAVHGLAGLMMAVLCRSPYGPVAALLVLLPMCVSWWAFAQ
                     YHRERAAHQATIRALVQAVDIKDGYTRGHSERVGQASMMIARELGMDDERVEVLRFAGI
                     LHDVGKLGVPTRLLRKDGPLTPEERRVIELHPEYGHEMVRGIGFLGEARAAVLHHHERL
                     DGSGYPYGLVGSQIPESARVVAVADAFDAMTSTRSYSRARPVPVALAELKRCSGSQFDP
                     VMVAALVEAVGRAGWRPAVTADDVHPPRIPPPGAPVSSPPGAHR"
     gene            complement(15991..16302)
                     /gene="rsrA"
                     /locus_tag="SCNRRL3882_RS13465"
                     /old_locus_tag="SCNRRL3882_2664"
     CDS             complement(15991..16302)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326971.1"
                     /locus_tag="SCNRRL3882_RS13465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2664"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_010047599.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEILDHLYEFLDREMPDSDCVKFEHHFEECSPCL
                     EKYGLEQAVKKLVKRCCGHDDVPGDLRDKVMGRIELIRSGQAVPEQDVTASPTTSQDS"
     gene            complement(16299..16985)
                     /gene="sigR"
                     /locus_tag="SCNRRL3882_RS13470"
                     /old_locus_tag="SCNRRL3882_2665"
     CDS             complement(16299..16985)
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="SCNRRL3882_RS13470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2665"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_010047600.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTEHGQAEQPEGQGGTGAETAAERNARFERDALEFL
                     DQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRK
                     KQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKEALQAIPEEFRIA
                     VYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARDRGMVPAGAGESNE
                     AKGSGS"
     misc_feature    complement(16948..16963)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.19"
                     /tool="antismash"
     misc_feature    17041..17055
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.77"
                     /tool="antismash"
     gene            complement(17242..17871)
                     /locus_tag="SCNRRL3882_RS13475"
                     /old_locus_tag="SCNRRL3882_2666"
     CDS             complement(17242..17871)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119817.1"
                     /locus_tag="SCNRRL3882_RS13475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2666"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_010047601.1"
                     /transl_table=11
                     /translation="MTNEIIATDTGDARITWHRAEKARLVLAVSHGAGGGIEARDLQAL
                     ARVLPEHGVSVALVEQPWRVAGKKLAPAPKTLDAGWRGIWSAVAAPGLPVISGGRSAGA
                     RVACRTAVELGARAVLALSFPLHPPGKPEKSRAAELLGSGVPTLVVQGGNDPFGKPGEF
                     PEGPYELVEVPYGDHGFAVPKRAEITQQEAVAVITDAVVEWTGSLG"
     gene            complement(17873..18688)
                     /locus_tag="SCNRRL3882_RS13480"
                     /old_locus_tag="SCNRRL3882_2667"
     CDS             complement(17873..18688)
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="SCNRRL3882_RS13480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2667"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_010047602.1"
                     /transl_table=11
                     /translation="MCGRYAASRRPEDLAGIFEIEKWEPEETLEPDYNVAPTKEVYAVL
                     DRPLKDADDPRPVRQLRTLKWGLVPSWSKTPEGGARMINARAETVHEKPSYRRAFTSRR
                     CILPADGYYEWVTGTQERELEVEGKKKRPRKQPYFVTPADGSVFAMAGLYEFWRDKTLP
                     DDHPQAWWVTCSVITTEAEKSPLAVSPADGPRALAEIHPRMPLMLTPDRWDAWLDPART
                     DPDDLRELLAPPPAGLMRAYPVTTAVSNVRNNGPELLKELEGPEEGTLF"
     gene            18739..19461
                     /locus_tag="SCNRRL3882_RS13485"
                     /old_locus_tag="SCNRRL3882_2668"
     CDS             18739..19461
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="SCNRRL3882_RS13485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2668"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_010047605.1"
                     /transl_table=11
                     /translation="MDSTATASLASLWDEVSGTQPDPDLWVVIASLGVALAVVIPHGLW
                     RISRNAITIAHEGGHGLVALLSGRTLTGIRLHSDTSGLTVSRGKPYGIGMILTAASGYT
                     APPLLGLGGAALLGAGRITLLLWLATALLLAMLVMIRNAYGALTMVITGGLFVLVSWLA
                     GPQVQAAFAYVVVWFLLIGGVRPAFELQAKRARGGAGDSDADQLSRLTHVPAALWFFLF
                     HAVSLCSLLGGGRWLLGL"
     gene            19568..20884
                     /gene="aroA"
                     /locus_tag="SCNRRL3882_RS13490"
                     /old_locus_tag="SCNRRL3882_2669"
     CDS             19568..20884
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522882.1"
                     /locus_tag="SCNRRL3882_RS13490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_2669"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_010047607.1"
                     /transl_table=11
                     /translation="MAPNTADTALWPAPHASGAVDATVHVPGSKSVTNRALVLASLASE
                     PGWLRRPLRSRDTLLMAGALRAMGVEIEEGVGPDGTGEAWRVLPTGLRGPATVDVGNAG
                     TVMRFLPPVAALADGPVRFDGDPRSYERPLNGVIDALRQLGARIDDDGRGALPLTVQGG
                     GALDGGPVAIDASSSSQFVSALLLSGPRFNQGVEVRHTGATLPSMPHIRMTVDMLRAVG
                     AQVDTPESGGEPNVWRVTPGALLGRDLVIEPDLSNAQPFLAAALVTGGKVVIPDWPART
                     TQPGDRLREIFTEMGGSCELTEFGLVFTGSGSVHGIDVDLSEVGELTPGVAAVAALADS
                     PSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRRLHGGIFHTYDDHRM
                     ATAGAIIGLAVEGVQIENVATTAKTLPDFPDLWTGMLGA"
ORIGIN
        1 agaccatcat gcccgcgata ccgatcgcgg atatcagctt gcgcttcacg ccaccctcct
       61 cagggatgcc accgaccccc ctgctccccg cggtgaacgt ggggccaggc cctggaccaa
      121 tggtgtagac cagtaggggg agcttggacc agaccaccag gcctgtcaag agtccggaat
      181 cagctctgac cagccgttat gcgacctaca tatgcaggaa cctttaagta agaacccggc
      241 gaaaacccgg ccgcgcacgg catactccag gtagaccact ggagttgtgg actagaccaa
      301 aagcggcgcc gacggtatac aagtgagatc gtgtcggccc aggagccggg aaggcggagc
      361 atgagcaccg acatcagcag tgcggagaac gagagcgggg cgcccgtccg caccgcacgc
      421 gtgcccaagt actaccgcct gaagaagcac ctgctcgaca tgaccgagac ccaggcgccc
      481 ggcacgccgg tgccgcccga gcgcaccctg gcggccgagt tcgacacctc gcgcacgacc
      541 gtgcgccagg cgctccagga gctggtcgtc gagggccggc tggagcgcat ccagggcaag
      601 ggcacgttcg tcgccaagcc gaaggtctcg caggcactgc aactgacctc gtacaccgag
      661 gacatgcgcg cccagggtct cgaacccacc tcgcagctgc tggacatcgg ctacgtcacc
      721 gccgacgacc gcctcgccgg gctgctcgac atcacggccg gcggacgggt gctgcgcatc
      781 gagcggctgc gcatggccaa cggcgagccg atggccatcg agaccaccca cctgagcgcg
      841 aagcgcttcc cggccctgcg ccggtccctg gtgaagtaca cgtccctcta caccgcgctc
      901 gccgaggtct acgacgtcca tctcgcggag gccgaggaga ccatcgagac ctcgctggcc
      961 actccgcgcg aggccggcct gctcggcacc gacgtcggcc tgccgatgct gatgctctcc
     1021 cgtcactcgc tggaccggga cgggcagccg gtggagtggg tgcggtcggt ctaccgcggc
     1081 gaccgctaca agttcgtggc gcgtctgaag cgcccccagg agtagggcgc gcggcgcggc
     1141 acgactgctg ctgagctcgg tttcttttgg ataccgcatt acggacgagg ggttccgttc
     1201 ccgccgcacc ctgacctaga ttgcctgcgc attgcacagg tgatcactga ggggacggag
     1261 ccgcctgatg tcgcaagccc cagaagccag cagaggggcg atggtgacgc cgatgcgcgt
     1321 cgtcatcggc ctctgcctca tagcgccctt cgtggccatg ctgtgggtcg gctcgtacgc
     1381 caagaccgac ccggccttca tcgggatccc gttcttctac tggtaccaga tggcgtgggt
     1441 gctgatctcc accgcgctga cgatgatcgc ctacaagctg tggcagcgtg accagcgcgc
     1501 ccgctctgcc gcgaagggcg gtgcgtccga gtgaaggacg gcgtgaacgg cgtcgcactc
     1561 gccgtcttca tcttcttctt cctggccgtc acggtcatgg gcttcctggc cgcgcgctgg
     1621 cgcaaggccg agaacgagca cagcctggac gagtggggcc tgggcggccg ctcgttcggc
     1681 acctggatca cctggttcct gctcggcggc gacctgtaca cggcgtacac cttcgtggcc
     1741 gtaccggcgg cgatctacgc ggcgggcgcg gccggcttct tcgcggtgcc ctacacgatc
     1801 ctcgtctacc cgctgatctt cacgttcctc ccccgcctgt ggtcggtctc gcacaagcac
     1861 gggtacgtga cgacgtccga cttcgtccgc ggccggttcg gctcgaaggg cctgtcgctg
     1921 gcggtcgcgg tgaccggcat cctggccacg atgccgtaca tcgcgctaca gctggtcggc
     1981 atccaggccg tactggacgt catgggcatc ggcggcggcg agaacaccaa ctggttcatc
     2041 aaggacctgc ccctgctgat cgccttcggt gtgctggcgg cgtacacgta ctcgtcgggt
     2101 ctgcgggcgc cggcgctgat cgcgttcgtg aaggacaccc tgatctacat cgtcatcgcg
     2161 gtggcgatca tctacatccc gatcaagctg ggcggcttcg acgacatctt cgccaaggcg
     2221 agcgacgcgt tcagccagac caacccggcg acgggcgcgc cgcgcggtgc gctggtcccg
     2281 gccgaggcgg ggcagtggac gtacgccacg ctggcgctgg gctccgcgct cgcgctcttc
     2341 atgtacccgc actcgatcac ggcgacgctg tcctcgaaga accgtgaggt gatccgccgc
     2401 aacaccacga tcctgccgct gtactcgctg atgctgggcc tgctcgcgct gctcggcttc
     2461 atggcgatcg ccgccgggat caaggtgcag aacgggcagc tggcgatccc gcagctgttc
     2521 gagaccatgt tcccggactg gttcgcgggc gtggccttcg cggcgatcgg catcggggcc
     2581 ctggtcccgg cggccatcat gtccatcgcc gccgcgaacc tcttcacccg caacatctac
     2641 aaggacttca tcaagcccga cgccacgccc gcgcaggaga ccaaggtctc caagctggtc
     2701 tcgctgctgg tgaaggtggg cgcgctggcc ttcgtcctca ccatggacaa gacggtcgcc
     2761 atcaacttcc agctcctggg cggcatctgg atcctccaga ccttcccggc cctggtcggc
     2821 ggcctgttca cccgctggtt ccaccgctgg gcactgctcg cgggctgggc cgtcggcatg
     2881 atctacggca cggtcgccgc gtacggcgtc gcctcgccga cccagaagca cttcggcggc
     2941 tcctcgaagg agatcccggg catcggcgag atcggctaca tcggcctcac ggcgttcgtc
     3001 ctgaacgtcg tcgtcaccgt cgtcctgacc ttcgtcctca aggccctgaa ggcccccgac
     3061 ggcatcgacg agaccaagcc ggaggactac acggcggacg cgggcgaccc cggcgtccag
     3121 gtggagctgc cgccggcgac ggcgggcacc tcgcactgag tcgcaggtga cagcgggccg
     3181 tcggtgaaag acccggcggc ccgttgtcat acccgtcccg cacactcgga ccatggacat
     3241 cctcatccgg cgggtgaagc ccgccgaata cgacgccctc ggcgagatca ccgcccaggc
     3301 ctacctgaag gacggcctcc tcgacttcgg ggagagcgac ggatacctcg gcgaactcag
     3361 ggacgtggcc aagcgggccg ccgcggcgga cgtcctggtg gccacccaag gcgaacacct
     3421 cctcggtggc gtcaccttcg tccccgccgg cggacccatg gccgacatcg cccgaccctc
     3481 agaagccgag atacggatgc tcgccgtcgc ccacgaggcc cgcggccgcg gcgccggaga
     3541 ggccctcgtc cgcgcctgcg tcgaccgcgc ccgtgcgacg gacggctgtg tacgcgtcgt
     3601 cctgtcgacg cagcgcacca tgcactccgc ccaccgcatc tacgaacgcc tcggcttcgt
     3661 ccgtaccccg gagcgcgact ggaatcccgt tccggagctc ggcgacatca ctcttctcac
     3721 ctacgagttg acgctgtgaa accgtcgcga cactacatct aggggtgctt tcaccacccg
     3781 gcacaagatg tatgctcatg ctcgctgtcg ccgcagggga atccggtggg aatccggaac
     3841 tgtcccgcaa cggtgtaccc atgccttctt atgcgtgtat gggagtcagt ccgaggacct
     3901 gccgacagcg cgcccggccg tccggccggt gcgcactgac gtccgggcct cgcggagtgg
     3961 gccggtggac gcgacgccgc gtgcgttcgt gtgctgcccc ctgccctgcg tgaggtcccc
     4021 gtgccgagcg agggagagcc ccacgtgacc atcgcgccag ccgatccggt ctcagccgcc
     4081 gaagatgagc acgacggtcc cggtgccgcg ctgctgcgga ccctgaccga gctgaccgcc
     4141 gacctccccg acgccgaccc cggccgggtc gccgccgccg cgctgcgcgg ccggtccgca
     4201 cgggccgacg cgtcggagtt gcgcgagctg gcgacggagg cggccgccgg cctcatctcc
     4261 gaggatcccg tctactcccg gctggccgcg cgcctgctga cgatcgggat ccgcgccgag
     4321 gccgcctcgc agggagtcac gcgcttcacc gagtccgtgg ccgtcgggca ccgggagggc
     4381 ctcatcgccg accggaccgc cgcgttcgtg cgcacgcacg ccgcgcggct cgacgccctg
     4441 atcgacacgg ccgccgacga ccgcttcggc tacttcggcc tgcgcacgct gcacagccgc
     4501 tacctgctcc ggcacccgat cacccgcaag gtcgtcgaga cgccccagta cttcatgctg
     4561 cgcgtcgccg ccgggctggc agaggacgac accagccgct cggtggacga agtggccgcg
     4621 ctctacgggc tcatgagccg gctcgactac ctcccctcct cccccaccct cttcaactcc
     4681 ggcacgcggc acccccagat gtcgtcctgc tacctcctcg actcccccaa ggacgagctg
     4741 gactcgatct acgaccgcta ccaccaggtg gcgcggctgt cgaagcacgc cggcggcatc
     4801 ggaatcgcgt actcccgcat ccgtgcgcgc ggttcgctga tccgcggcac caacggacat
     4861 tccaacggca tcgtcccgtt cctgaagacc ctcgacgcct cggtcgccgc cgtgaaccag
     4921 ggcggccgcc gcaagggcgc cgccgcggtc tacctggaga cctggcactc ggacatcgag
     4981 gagttcctgg agctgcgcga caacaccggc gaggacgccc gccgcacgca caacctgaac
     5041 ctcgcgcact gggtgcccga cgagttcatg cggcgcgtga acgccgacgg gcagtggtcg
     5101 ctgttctccc cctcggacgt tcccgagctg gtcgacctgt ggggcgagga gttcgacgcc
     5161 gcgtaccggg cggccgaggc gaagggcctc gccaggaaga ccctgcccgc ccgtgagctg
     5221 tacggccgca tgatgcgcac cctcgcgcag accggcaacg gctggatgac cttcaaggac
     5281 gccgccaacc gcaccgccaa ccagacggcc gagccgggcc acgtcgtcca ctcctccaac
     5341 ctctgcacgg agatcctgga ggtcaccggc gacggggaga cggcggtctg caacctggga
     5401 tcggtcaacc tcggcgcgct cgtcgaccgg tccggcgggg acatcgactg ggagcggctg
     5461 gacgagaccg tccgtacggc cgtcacgttc ctcgaccggg tcgtggacat caacttctac
     5521 ccgaccgagc aggcgggccg ttccaacgcc aggtggcgtc cggtcggcct cggagtcatg
     5581 ggcctccagg acgtcttctt caagctgcgc ctgcccttcg actctccgga ggccaagcgg
     5641 ctctccaccc gcatcgccga gcggatcatg ctcgccgcct acgaggcctc cgccgatctc
     5701 gccgagcgca acggcccgtt gccggcctgg gagaagaccc gtacggcgaa gggcgtgctc
     5761 caccccgacc actacgacgt gcagccgacc tggccggagc gctgggcggc cctgcgcgag
     5821 cgcgtcgccg cgaccggcat gcgcaactcc ctgctcctgg cgatcgcgcc gacggccacc
     5881 atcgcctcca tcgcgggcgt gtacgagtgc atcgagccgc aggtgtccaa cctgttcaag
     5941 cgcgagacgc tgtcgggtga gttcctccag gtcaactcct acctggtgga ggagctgaag
     6001 cggctcggcg cgtgggacgc gcgtacccgg gaggccctgc gcgaggcgaa cggctcggtg
     6061 caggacttcg cctggatccc cgcggacgta cgcgccctct accgcacggc gtgggagatc
     6121 ccgcagcgcg gcctgatcga catggcggcg gccaggaccc cgttcctgga ccagtcccag
     6181 tccctgaacc tcttcatgga gacgccgacc atcggcaagc tctcctcgat gtacgcgtac
     6241 gcctggaagt ccgggctgaa gaccacgtac tacctgcgtt cgcgcccggc gacccgcatc
     6301 gcccgcgcgg cccaggccac cgtccccgtg caggccaccc cggatcccga agcggtcgcc
     6361 tgctccctgg aaaaccccga gtcctgcgag gcctgccagt aatgaccacc cagaacctcc
     6421 tcgaccccgg cttcgagctg actctccgcc cgatgcgcta cccggacttc tacgagcgct
     6481 accgggacgc catcaagaac acctggaccg tggaggaggt cgacctccac tcggacgtcg
     6541 ccgacctcgc caagctctcc cccgccgagc agcacctgat cggccggctg gtcgccttct
     6601 tcgccacggg tgactcgatc gtcgcgaaca acctggtgct gacgctctac aagcacatca
     6661 actcccctga agcgcggctc tacctgagcc ggcagctctt cgaggaggcc gtgcacgtcc
     6721 agttctactt gacgctgctc gacacctacc tccccgaccc ggaggaccgc gccgccgcgt
     6781 tcgccgccgt ggagaacatc ccctccatcc gcgagaaggc cgggttctgc ttcaagtgga
     6841 tggactcggt ggagcagctc gaccggctgg agacccaggc cgaccggcgc cgtttcctgc
     6901 tgaacctcat ctgcttcgcc gcgtgcatcg agggcctgtt cttctacggt gccttcgcct
     6961 acgtctactg gttccgcagc cggggcctgc tgcacggtct ggccaccggc acgaactggg
     7021 tgttccgcga cgagacgatg cacatgtcct tcgccttcga cgtggtcgac accgtccgca
     7081 aggaggagcc ggagctgttc gacgaccagc tccggcagca ggtgacggac atgctccgag
     7141 aggccgtcga ggccgagctg cagttcgcgc gcgacctgtg cggtgacggc ctcccgggca
     7201 tgaacaccga gtcgatgcgg cagtacctgg agtgcgtcgc cgaccagcgg ctcagccgcc
     7261 tgggcttcgc tccggtgtac ggctccgaga accccttctc cttcatggag ctccaggggg
     7321 ttcaggagct gaccaacttc ttcgagcggc ggccctccgc gtaccaggtg gcggtggagg
     7381 gcaccgtcga cctggacgag gacttctgag cgcgctcgcc ctcacgggcc tcctgggcct
     7441 ccctgatctg tcggtcgacg cgccggtcgc gcacgatacc gatcactgac gggaggacca
     7501 ggaggaccag catcccgagt acgaagatca ttgcgatgag cgtctgtgcc tggttcgtgt
     7561 ccatggacac cactgtcgcg ccgatgactc cttaccgtca gtggcagtac tgccgtggac
     7621 cctcgaatta ctgccactga cgaggcacac tggaggcatg ctccagaacg tggccgtcgt
     7681 cctcctcgac ggcgtgaacc ccttcgagct cggtgtggtg tgcgaggtct tcggcaccga
     7741 ccgcagcgac gacggcctgc cggtctacga cttcgcggtg gcctcggccg agggcccggc
     7801 cctgcgcacc aacacgggct tctcgctgca cgtcgagcac ggtctggagc ggctggagac
     7861 ggccgacctg atcgccgtgc ccgccgggca ctgctacgag tcccgggact tcccgccgga
     7921 gctgctggac gccctgcggc gcggggccgg ccgcggcgcc cgggtgctca gcgtctgctc
     7981 cggcgtcttc gtgctggccg cggccgggct gctggacgac cggcgctgcg ccgtgcactg
     8041 gcggcacgcg caggccctcg cccggcagta cccgcgggtg gccgtcgagc cggacgtgct
     8101 ctacgtcgac gaggacccgg tgatcacctc ggccggcacg gccgccggga tcgacgcctg
     8161 cctccacctg gtgcgcaagg agcagggctc cgaggtcgcc aacaagatcg cccggcggat
     8221 ggtggtgccg ccgcaccgcg acggcgggca ggcccagtac atcgagcgcc cgctgccgca
     8281 ctccgaggcc gacacgatcg gggaggtgct ggcgtggatg gagcggcacc tcgacgagga
     8341 ggtcaccgtc gagcagctgg ccgcccgcgc ccacatgtcc ccgcgcacct tcgcccgtcg
     8401 cttccagcag gagaccggga cgacccccta ccgctggatc ctgcgccagc gcgtgctgtt
     8461 ggcccagcgg ctgctggagg cgacggacga gacgatggac gcgatcgccg gtcgaacggg
     8521 gttcggcaac tcggccacgc tgcgccacca cttcgtccgg gccgtgggca cgacgccgaa
     8581 cgcctaccgg cggaccttcc ggggccccga agcggcctga gccggtccca cgctcacctc
     8641 gccaccggcc gcagcagcag gtcgtgcggc cgcagcgtga tgccgacgcg ggtgccgtcg
     8701 ttcgagccga ccacctgctc gaagcggtac ttggtggcca gcgccgccgt gatcagcgtc
     8761 agctgcgcca tcgagaagtg gtcgctgggg cacttgcgat tgcccacgct gaacgggctc
     8821 atggcgtgct tcgggatgtc cttggcccgg tccggaagcc agcggtcggg gtcgaactcc
     8881 aggttccgct catacgactt cgggtcgcgc tggatcgcgt acgggctgta gacgatgtcc
     8941 gccccggccg gaatccggta tccgccgagt tcggtgtccc gcactgcccg gcgcgtcaga
     9001 atccagacgg cggggcgcaa acgcatggcc tcgaccacga cattgttggt gtgcctgagt
     9061 ccccggacgt cctcgaatgc caccggcctc ccaccggcga cggcttctac ttcgtcgcgc
     9121 acccggtccg cgtgttctgg gtgttccgcg agcatatgca acagccacat gatcgtggag
     9181 gcgacggttt cgctgccagg ggtgaggatt gcgacgacct gatcatggat ctcctgttcc
     9241 ccgatggggt cgccattctc gtccgtcgcc tccagcaatg ccgtcagcaa atcgtccggc
     9301 ttttgaccgg atgcgcggcg ctcggcgacg atctcgtcca ccaggagatg caaatcggcc
     9361 aaagcccggt tgaattcgcg gttggccggg agcggcagct tgtagagcgg tccgagcggc
     9421 accaccatcc gccggtacat cccgcggaag acggtggcga gcgcgacaca cagccgctcc
     9481 gcccgctcgt ccatgtagtc gccgcgcagc aggcagcggg ccgcgatgcg cacggccacc
     9541 cggaaggact cggaggtgca gtcgatggtc tcgccgggct tccagcgctc ggtgagcgcg
     9601 tgcgcctcct cctccatgat cggcccgtag gcggggatgg cgtcgagccg gaaggccggc
     9661 tggatggtgc gccgctggcg ccggtgccgc gggccgttcg cggtggccac gccctccttg
     9721 ccgagcaggc cctccaggga ctcccacagc ggtccggcga tgatgaagtc gttgctcagc
     9781 gcgagggcgc cggtgagcgc cggggtggtg acggcgtaca ccgtcttcgg tccgagcttc
     9841 agccggacca cctcgccgtg gtcgcgcagc cgcgacatga acgccagcgg gtcgcgcacc
     9901 agcttccagc cgtgtcccag gacgggtaca ccgccgcccg cccggggcgg ttcacgcaac
     9961 tccggggcca gaggggcttc aggcttcaca gactcgacgg tcatttctca cctgccgctt
    10021 cgttgttgac gtacgggggc gtggaccggt cgtcccagct gtcgaccatg taccggccgg
    10081 actcgtgatg gaaccagtag acggaactga accagttccg catattgctc agacaggccc
    10141 gcacggcggc gctgagttcc tttccccgca cggtgccgtc ggcgagggcg tcggcgaacc
    10201 gtaacgcttc ctgttcgacg tcgaggaatt ccgtgatgca tttctcgacg cggcgcctga
    10261 cttcgacgac cgcctgttcc agggtcagcc cctcatgagt gatgagactg attccgagat
    10321 tgtgcacctc gtcgcccgct atttccttcg gaagcgagca gaggtcgttg taccaggcgg
    10381 cgaactcctg actcagcagc gccgcccgcc gatatgccgg gtgtttccgt acggtggctg
    10441 ggagttcgca tcccgcggcc ggctccagca gatccgtcca gatccagtgg gcgaaggtga
    10501 gccggcgcag caggagatac tcctcgaccg agggcacgat tccgtgggtg cggttgtaga
    10561 actcccggtc gtacgcgtcg atcaccgcgt ggaagtgccg cgcgaaccgg aggttccatg
    10621 tccccggcag gaaggcgtac agccgcagca cgctgtccgc gaacccggcg accagtgggt
    10681 cctcgtggtg cagatgctcc ccgggggagt cgagggccga gtgcagccgg tcccgcagcc
    10741 gccgccaggc gaccggacgg ccgtgcacga tgtcgcggtc gtggcggtcg tcccagacga
    10801 agaaccaggc gctgtagtcc gcgatcgcct gcatcacctc gtcggaggcg ccgatgtagt
    10861 acccggccat gaggtccgtg tagcacaggc cgtcggcata ttcctccacc ttgtccgcgg
    10921 gcatgagccg tttttcgagc agccaggcgc gggtcttctc ctggcacttc ggccaatacg
    10981 ggtggagttg ccggggaaac gccgcctcga tcaccggaag ggagagcgac ggtggaaccg
    11041 cgatggtggt cggtgtcgat gtggtgccgt gtgacaaagc atgcacgaac taacccctct
    11101 cagccgccag ttggcgcggg cgcccctcct tccgtgctgg gcgtgcgccg ttgcataccc
    11161 cgctactccc attcagcact acaactgacc gttctgggaa cgtatttgct tcattcactg
    11221 ccccacaggg ctgggaacct cccgttgtgt gactggtacc tgatcaccag aagagcggaa
    11281 gcgatcgaac gtgcgacgga caggcgaacg aagcagacga acggcgcctg tccggggcgg
    11341 gaagcccgaa cagacgccgt tcgcctggtg atcctgaggt ctcagtcgtt cgcgacgacc
    11401 gggtaccggg gctcgttctc ggccatctgc cgcagcgcgt ccttgcgttc gcgcttcgag
    11461 aggcggtcga tgtagaggta gccgtacagg tggtcggtct cgtgctgcaa acaccgagcg
    11521 aagtatccgg tgccgcgcac ccggatcggg ttgcccttct cgtcctgccc ggtcacctcg
    11581 gcgtagtcgg gccgcgcgag cggcgcgtac gcggtcggca ccgacaggca gccctcgttg
    11641 ctgtcgtcca gccggcgctt ctcggcgggc agttcgacga gcttggggtt gcagacgaca
    11701 ccggtgtgcc ggacgccctc gtcgtccggg cagtcgtaga cgaagacctt caggtcgaca
    11761 ccgatctggt tggcggccag gcccacgccc tcggcggtgc gctgcgaggc gaacatgtcc
    11821 gccaccagct gctggaggtc gtcgccgaac tcggtgacgt ccttgcactc cttgtggagc
    11881 accgggttcc cgaccaccgt gatcggccgc gaggtccccc gctcccgcca ggccgcctcg
    11941 cgctcctcgc agtcctccgt gtcgatcacg tacccctcgt catcgacggg gagcacgccc
    12001 gcgcgctgct gatcggtgtc ctgctgagcc atgacgttac gtacgccttc ctgaaccaaa
    12061 ccgggctgag atgctgatac aggttacgcg ggtgtcggac gccgctttca ggggcgcggg
    12121 gacctgtgcg agaaaccacg acggcgccgc acccggcaag gggcctagca cacctcttcc
    12181 aaatcccgcc aatcccgaga atccggactg tcggccaccc acccgtccaa aagccccctc
    12241 accagcgaag ccggcgcggc cagcccgcac tcccgctcgg gaacccacag ctgcccgtcc
    12301 gtccgatgcc ccagcggccc gggatgcccc ggctcactgt ggtcgtgcgg gtcgaggtgc
    12361 tccccgtcac cctcgtccga cggcatccgc gactcggaac acatccggca cagcaaccgc
    12421 accgaagagg accagtcctc ggcggcgaac ccggcatccg cggcaagctg ctccagcgcg
    12481 tcccggtcgg actccgtcgc cgcctccagc agcaccaccc acgtcggcac cggcgacggc
    12541 gcccacagct cgatctcgtc gaacaccggg taggtgtgcc ccgcggccgt ggtccgctcc
    12601 ccgtgcggca cgccgtcgtg cagcacgacc tcaccccagc gccgccccga cgacggcagc
    12661 ggaatggaca gcacctcgat ccgcgcgggg tccagccgcc gcccccacac gacctcggcc
    12721 tccccctccg gggacagccg tacggccgcg ctgcccaggt ccatgccgac cggctcaccg
    12781 gagtcgttgg ccgcccccgg cacccgcagt ccgtaggcct gccaggcgcg ccgggccagt
    12841 ggccagtcct ggagggcggt cgcggcgatg ccgacgttcc accagtcggg cgctccggtg
    12901 tcccggtcga gcagggccac ggccctgagg cccgccgccc gcgcctgctc ccagtcgtgc
    12961 cggaacttgt gcagcagggc gaggttgaac caggactcgg acagccaggg ctccaggtcg
    13021 gcggcacgtg tcaacagtgc gcccgcgtcc tcgtaccggc cgtcgccgat gagagtgaac
    13081 gcccggtctg tggcctgccg ccaggaggcg gagggccggt gccgtccctt gccgaagatc
    13141 ctcacgattc ccgcctgcca gttccgtgcg gtgggctggc cgtagctgtg tttcgagccc
    13201 ccggacacct tcttcttcgc atccaaccac gtacggcctc cggggcgctc attacccatg
    13261 ggttacccag tcaggcgcat ggtcagactg ctccttgcca gtacccgggc cagcgattcc
    13321 accacctccg gggcgtactc cccggcggtg gcgagccgga gttcctccag cgccgtcagc
    13381 ggcccgccgg gaccaccttc ccgggacttc tcctcgtacg cgttcacggc ccggacgatc
    13441 cgcgcggcga gcggctgctc cgcaaagggg tcggcctgcc gctccacgac cacggcgacc
    13501 gcctcgtcga cgcccgtctg ccggacgacg gccccgccga gcagcgcgat ccgccgctgt
    13561 tccgcggcgg gcaggccggc ggtggcgccc gacggcaccg ggtcgacgag gctcagctgg
    13621 ccgatgtcgt gcatgagcgc ggcgtactcc agcacggcca gctcgggttc ggtgaggccg
    13681 aggtcacgcc ccacggccag actgagcgcg gcgacacggc gggcgtgccc ggccggggtg
    13741 tacccggcga cctcggtggc ccgcgcgagg gaggcgatgg tctgccggta ggtcgcccgg
    13801 acggcggcgt accggcggaa cgacatctgg gcgagcagca gcggcacgga gaagacaggc
    13861 agtgcccaca ggcccaccac ggcgaccgcc agcgccatca ccgcccccgt cgcgatgacg
    13921 gcggccccga tgccgcacac ggcccgcagc tcgtcccgca gcacgggccc gaagggccag
    13981 ccggtgcggg agtgggccag cgcggcggcg agcacggcat cgcacagcgc ggtcagggac
    14041 agcagcgcga gcagcagcag cgcgtaggcg ggaccgcccc agtcgtcgaa catgccccgg
    14101 ttgtaggggg gctggaagca cacggcgacg aacccgacgg tgagcacccg gcgcgccaga
    14161 tggtcgagcg tgggcccctg accgcgtgcc acgtgcggca cgctgccgag cagcgaggcg
    14221 gccagcacga cggcgacgac ctgggcgggg ccgtggtgcg tggcccgccc gccggcctcg
    14281 ccgagcagcg cgtacgacag ggccgcggcg gccccgagcg gcgccggctc cctgacctgc
    14341 gccccgttgc gccgggcgag ctccccgacg gtgacgagga cgccgaaggc gagggcgccc
    14401 cggcgttcct ccagcccgtg gtggagggtg acggcgaggg agccggcggc gaggagggcg
    14461 gcgcaggcgt ggacgagggt gaacagcggc ggcgggcggt acgcgctcac cggtgtgctc
    14521 ccggcgggct ggagacaggt gcgccgggcg ggggaatccg gggcgggtgg acgtcgtcgg
    14581 cggtcacggc ggggcgccat cccgcccggc cgacggcctc cacgagggcc gcgaccatca
    14641 ccgggtcgaa ctggctgccg gagcagcgct tcagctccgc cagggcgacc gggacgggcc
    14701 gggccctgct gtagctccgt gtggaggtca tggcgtcgaa ggcgtccgcg acggccacga
    14761 cccgcgcgga ttccgggatc tgactgccca ccaggccgta ggggtacccg ctgccgtcca
    14821 gccgttcgtg gtggtgcagc acggcggcgc gggcctcccc gaggaagccg atgccgcgca
    14881 ccatctcgtg cccgtactcg gggtgcagct cgatcacccg tcgttcctcg ggcgtcagcg
    14941 gcccgtcctt gcggagcagc cgggtgggga cgcccagctt gccgacgtcg tgcaggatcc
    15001 cggcgaaccg gagcacctcg acgcgctcgt cgtccatgcc cagctcgcgc gcgatcatca
    15061 tggaggcctg cccgacgcgc tcactgtgcc cgcgggtgta cccgtccttg atgtcgacgg
    15121 cctggaccag cgcccggatc gtcgcctggt gggcggcccg ttcccggtgg tactgcgcga
    15181 aggcccacca ggagacgcac atcggcagca gcacgagcag ggccgccacg ggaccgtagg
    15241 ggctgcgaca cagcacggcc atcatcagcc cggccagccc gtgcacggcg atcggcgcga
    15301 gcgagcgcgc caccagtccc cgccaggccc gccgcaccgg cacccgctcg gccacggcca
    15361 ggatcccgcc gtccagcacc gcgagcacca ggcagaacgc cagcacggcc gccccggccg
    15421 gcccgagcgc gtaggggacg tcgcccgcga ggacggcgtc ccgcccgccc agcgcccggt
    15481 gcacccgcgc cgcggcccag acgccgagga cgagctgagc ggcccgccag acccgccgca
    15541 gcgccacggg ccgctgctcc acgtgcgaga gcagcgcacc gggcacggcc accagggcgg
    15601 cggcgggcgc gggcagcagg aaggcaccgg cgagcagcac gggatagaag gtcccggccg
    15661 gatgggagat cccgacgaac cgggaccggg cgacgcgctc gcagcccgcg tacagcgcgg
    15721 cgagcagcag cacggcccac cagggcgtgc ggacgcccgg cagcggcagc aggcagagga
    15781 gggcggcgaa gacgacacag gcgacgtaca cacgtgcccg caccggtacc gcatccatga
    15841 gccctccccc ggccatgtcc atcaggcccg gagcctagga cggcggtggg gggctccgcg
    15901 ggcggataac ccgcggatta gcacgttcga gtgatgcgtt cgaggatgac taccccctca
    15961 gaggtggggt agttgaaaag cgcgggagtg tcaggagtcc tgcgacgtgg tcggcgaggc
    16021 ggtgacgtcc tgctcgggga cggcctggcc ggagcggatc aattcgatcc gccccatgac
    16081 cttgtcccgc aggtcgccgg ggacgtcgtc atgcccacag cagcgcttga cgagcttctt
    16141 cacggcctgc tcgagcccgt acttctcgag gcagggcgag cactcctcga agtggtgctc
    16201 gaacttcacg cagtccgagt ccggcatctc acggtcgagg aactcgtaga gatgatcgag
    16261 gatttcgctg caatccgtct cgtgcggctc tccgcagctc atgaccccga gcctttcgct
    16321 tcgttcgact ctccggcgcc ggccgggacc atcccgcggt cacgggcgta gtcctccagc
    16381 atgccgcgca gctgacggcg gccccggtgc agccgggaca tcaccgtacc gatgggtgtc
    16441 cccatgatgt cggcgatctc cttgtaggca aagccctcga cgtccgccag atagacggcg
    16501 atgcggaact cctcggggat cgcctggagc gcttccttca cgtccgagtc gggcaggtgg
    16561 tcgagcgcct gcgactccgc ggagcgcaga cccgtcgaca tgtgcgactc ggcacgggcg
    16621 agctgccagt cctcgatctc ctcggccgcg gagcgctgcg gttcccgctg cttcttgcgg
    16681 tacgagttga tgaaggtgtt cgtgaggatc cggtacagcc acgccttgag attggtgccc
    16741 tcgcggaact ggtggaagga cgcgtacgcc ttcgcgtacg tctcctgcac caggtcctcg
    16801 gcgtcggccg ggttgcgcgt catgcgcagc gcggccgagt acatctggtc gaggaactcg
    16861 agcgcgtccc gctcgaagcg cgcgttgcgc tccgcggccg tctccgcgcc cgtgccgccc
    16921 tggccctcgg gctgctccgc ctggccgtgt tcggtccctg cgtcggtccc tgtgaccgga
    16981 cccacctcct ccagtgttct cgtgagaccg agaccggtct cacccgaatc ggaggataga
    17041 cgacgatccg gtccgcccgc cgcccgaata ggggcggtct tggccgcgtg cagcaccgtc
    17101 cagtccaggt cggcgcggct gctgcggctc gggcagaagg tcgaacccat gcggcggact
    17161 tcctctccta cggcatcggt gctggtctcc agcacgtacg tcccgcacaa cagtgctcgc
    17221 cgccccggca ttcccggagc tttacccgag tgacccggtc cactccacga ccgcgtccgt
    17281 gatgaccgcc actgcctcct gctgcgtgat ctccgcgcgc ttggggacgg cgaagccgtg
    17341 atcgccgtac ggcacctcga cgagctcgta cggcccctcg gggaactccc cgggcttccc
    17401 gaaggggtcg ttcccgccct ggacgaccag ggtgggcacc ccggagccca gcagctcggc
    17461 ggcgcgggac ttctcgggct tgccgggcgg gtggaggggg aagctgaggg ccaggacggc
    17521 gcgggcaccc agctcgacgg ccgtgcggca ggccactcgg gctccggcgc tgcgcccgcc
    17581 cgagatcacc ggcagcccgg gcgcggctac cgcggaccag atgccccgcc accccgcgtc
    17641 cagggtcttc ggcgccggcg ccagcttctt cccggccacc cgccagggct gctcgacgag
    17701 agcgacgctc acgccgtgct ccggcaggac ccgcgcgagg gcctggagat cccgcgcctc
    17761 gatgcccccg ccggccccgt ggctcaccgc cagcaccagc cgtgccttct ccgcccgatg
    17821 ccaggtgatg cgggcgtccc ccgtgtccgt ggcaatgatc tcgttcgtca cgtcagaaga
    17881 gtgtgccctc ttcgggccct tccagctcct tgagcagctc cgggccgttg ttgcggacgt
    17941 tgctgacggc cgtggtgacg gggtaggcgc gcatcagccc ggcgggcggc ggggcgagca
    18001 gctcgcgcag gtcgtcgggg tcggtgcggg ccgggtccag ccaggcgtcc cagcggtcgg
    18061 gcgtcagcat cagcggcatc cgggggtgga tctcggccag ggcccgcgga ccgtcggccg
    18121 gggacaccgc cagcgggctc ttctcggcct cggtggtgat gacggagcac gtcacccacc
    18181 aggcctgcgg gtggtcgtcc ggcagtgtct tgtcgcgcca gaactcgtac aggccggcca
    18241 tggcgaagac cgacccgtcc gccggggtca cgaagtaggg ctgcttgcgg ggccgcttct
    18301 tcttgccctc gacctccagc tcgcgctcct gcgtgccggt gacccactcg tagtagccgt
    18361 cggcgggcag gatgcagcgc cgggaggtga aggcgcgacg gtaggacggc ttctcgtgga
    18421 cggtctccgc gcgggcgttg atcatccggg cgccgccctc gggggtcttc gaccaggacg
    18481 ggacgagccc ccacttcagc gtgcgcagct gccgaaccgg gcgcgggtcg tccgcgtctt
    18541 tcagagggcg gtcgaggacg gcgtagacct ctttggtggg cgccacgttg tagtcgggct
    18601 ccagagtctc ctcgggctcc cacttctcga tctcgaagat tcctgcgaga tcctctggcc
    18661 tacgactcgc tgcataccgt ccgcacatac gtgtcacact gccagattcc atccgcccac
    18721 agggagccaa cgccgcacat ggacagcacc gcaaccgcct cgctcgcctc cctctgggac
    18781 gaggtctccg gcacccagcc cgaccccgac ctctgggtgg tgatcgcgag cctgggcgtc
    18841 gcgctcgccg tggtgatccc gcacgggctg tggcgcatct cccgcaacgc catcaccatc
    18901 gcccacgagg gcggtcacgg gctcgtggcc ctgctcagcg gccgcaccct caccggcata
    18961 cggctgcact cggacaccag cggcctgacc gtcagccgcg gcaagccgta cggcatcggc
    19021 atgatcctca ccgctgcctc cgggtacacc gccccgcccc tgctgggcct cggcggcgcg
    19081 gccctgctgg gcgccggccg catcacgctg ctgctgtggc tggccacggc cctgctgctg
    19141 gccatgctcg tgatgatccg caacgcgtac ggcgccctga ccatggtcat caccggcggc
    19201 ctgttcgtgc tggtgtcctg gctggccggc ccccaggtcc aggcggcgtt cgcgtacgtg
    19261 gtggtgtggt tcctgctgat cggcggggtg cgtccggcgt tcgagctcca ggccaagcgg
    19321 gcgcggggcg gggcggggga ctcggacgcg gaccagttgt cgcggctgac gcatgtgccg
    19381 gcggcgttgt ggttcttcct gttccacgcg gtgtcgctgt gctcgctgct cggcggaggg
    19441 cgctggctgc tgggcctgtg accagccggc ctgaggggcg cgggcctgtg ggtgcggctc
    19501 cgccgcgtcg gctcgaccgg cccccacggc gccgcacccg aacctctgct ccttataaag
    19561 tgaagccatg gccccgaaca ccgcagacac cgccctctgg cccgccccgc acgcgagcgg
    19621 agccgtcgac gcgacggtcc acgtgcccgg gtccaagtcg gtcaccaacc gcgccctggt
    19681 cctcgcctcc ctcgcctcgg aaccgggctg gctgcgccgc cccctgcgtt cccgcgacac
    19741 cctgctgatg gccggcgcgc tgcgcgccat gggcgtcgag atcgaggagg gcgtgggccc
    19801 cgacggcacg ggcgaggcct ggcgggtgct ccccacgggc ctgcgcggtc cggccacggt
    19861 cgacgtcggc aacgccggca cggtgatgcg cttcctgccg ccggtcgccg cgctagccga
    19921 cggtcccgtc cgcttcgacg gcgatccccg ctcgtacgag cgtcccctga acggagtcat
    19981 cgacgcgctg cgtcagctcg gcgcccggat cgacgacgac ggccgtggcg cgctgccgtt
    20041 gaccgtgcag ggcggcggcg ccctggacgg cgggccggtg gcgatcgacg cgtcctcctc
    20101 gtcgcagttc gtgagcgccc tgctgctgtc cggcccgcgc ttcaaccagg gcgtcgaggt
    20161 ccgccacacc ggcgccacgc tgccctccat gccgcacatc cgcatgaccg tcgacatgct
    20221 gcgcgcggtc ggcgcccagg tggacacgcc cgagtcgggc ggcgagccga acgtctggcg
    20281 ggtcacgccg ggcgccctgc tcggccggga cctggtcatc gagccggacc tgtccaacgc
    20341 ccagccgttc ctcgcggcgg cgctggtgac cggcggcaag gtcgtcatcc cggactggcc
    20401 ggcccgcacc acccagcccg gtgaccggct gcgcgagatc ttcaccgaga tgggcggctc
    20461 ctgcgaactg accgagttcg ggctcgtgtt caccggctcc ggctcggtcc acggcatcga
    20521 cgtcgacctg agcgaggtcg gcgagctgac gccgggcgtc gcggcggtcg cggccctcgc
    20581 cgactccccg tcgaccctgc ggggtgtggc gcacctgcgg ctgcacgaga cggaccggct
    20641 ggccgcgctg accaaggaga tcaacgaact cggcggtgac gtcacggaga ccgccgacgg
    20701 tctgcacatc cgcccgcgcc ggctgcacgg cgggatcttc cacacctacg acgaccaccg
    20761 catggccacg gccggcgcga tcatcggcct cgccgtggag ggcgtgcaga tcgagaacgt
    20821 ggcgacgacg gccaagaccc tgcccgactt ccccgacctg tggaccggga tgctcggggc
    20881 gtaggacgcg gggaccaggt catgcgccgc tacggcaagc acaccgacga ggacgacatc
    20941 cgcacccgtc ccggccgccg gaacacccgg ccccggacga acatccggcc caagcacgag
    21001 gacgccgccg agggcctcgt cctcaccgtc gaccggggcc gcctgacctg cctcgtcgag
    21061 gaccgcgtgg tcatggcgat gaaggc
//
