LOCUS       NZ_LT963352            22742 bp    DNA     linear   CON 13-FEB-2024
DEFINITION  Streptomyces chartreusis NRRL 3882 isolate NRRL3882 chromosome I.
ACCESSION   NZ_LT963352
VERSION     NZ_LT963352.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces chartreusis NRRL 3882
  ORGANISM  Streptomyces chartreusis NRRL 3882
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Wibberg,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2017) CEBITEC, Genome Research of Industrial
            Microorganisms (GRIM), Universitaetsstrasse 27, 33615, NRW, Germany
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 02:03:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,073
            CDSs (total)                      :: 7,984
            Genes (coding)                    :: 7,779
            CDSs (with protein)               :: 7,779
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 205
            CDSs (without protein)            :: 205
            Pseudo Genes (ambiguous residues) :: 0 of 205
            Pseudo Genes (frameshifted)       :: 91 of 205
            Pseudo Genes (incomplete)         :: 161 of 205
            Pseudo Genes (internal stop)      :: 14 of 205
            Pseudo Genes (multiple problems)  :: 56 of 205
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:02:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 213512
            Orig. end                         :: 236254
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT963352.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22742
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22742
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22742
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12742](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12742)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    32..51
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.13"
                     /tool="antismash"
     misc_feature    406..420
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.85"
                     /tool="antismash"
     misc_feature    411..425
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.18"
                     /tool="antismash"
     misc_feature    complement(415..428)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.7"
                     /tool="antismash"
     gene            690..893
                     /locus_tag="SCNRRL3882_RS00935"
     CDS             690..893
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SCNRRL3882_RS00935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158688460.1"
                     /transl_table=11
                     /translation="MVFQRRGLCESAVATVLNKQDKKKLVLAPARAARTWLAMHRHRWH
                     TRHQILARTSHYQARAARTHSP"
     gene            complement(911..1369)
                     /locus_tag="SCNRRL3882_RS00940"
                     /old_locus_tag="SCNRRL3882_0186"
     CDS             complement(911..1369)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047191.1"
                     /locus_tag="SCNRRL3882_RS00940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0186"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_010047191.1"
                     /transl_table=11
                     /translation="MEYSHSDTDLIKQPIGYWSWAAYKAVIARTRAALAGIGTTQPQWW
                     VLAQVASADNVKTRDEVSRLLRNYLDVGPETMESEIDTIIAQGWITEDAEGRLGLTAEG
                     RAFYDKAAALQDELWAERHAGISDEEYLTTLKVLQRFIHNTGGRAWHH"
     gene            complement(<1716..1852)
                     /locus_tag="SCNRRL3882_RS41020"
                     /pseudo=""
     CDS             complement(<1716..1852)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009332786.1"
                     /locus_tag="SCNRRL3882_RS41020"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVPDGLWEIAKPLILPPTMRPQGAGRRTRLMRRCSRRSSTCW"
     gene            complement(1916..2602)
                     /locus_tag="SCNRRL3882_RS41525"
                     /old_locus_tag="SCNRRL3882_0187"
     CDS             complement(1916..2602)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SCNRRL3882_RS41525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SCNRRL3882_0187"
                     /product="hypothetical protein"
                     /protein_id="WP_010047193.1"
                     /transl_table=11
                     /translation="MTRISASISPLVRPRRALTATALATLVLAGCGSESPSDGGSESKP
                     ASSVSAAESATSSEPEQAGFMAMLHKVAQPCLESESETQTETESGPSHKRPTGSGKEGR
                     ESLAPGETPPAVPIEPGAPTGPEAELNDRDRCMSVQHEQRIGQALQAVSEPTPAKVRKV
                     LNDLGYIDERIHGLRQDGKFTRFYLDLRERGGRLCEEGLAAGVETDISACVASAVGPFT
                     VAGPGE"
     misc_feature    3143..3158
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    3530..3543
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            3530..4591
                     /locus_tag="SCNRRL3882_RS00955"
                     /old_locus_tag="SCNRRL3882_0188"
     CDS             3530..4591
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018562692.1"
                     /locus_tag="SCNRRL3882_RS00955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0188"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_010047195.1"
                     /transl_table=11
                     /translation="MTTIKDVAQRAGVAPSTVSYVLSGSRKISEDTRRAVQVAIDELGY
                     HPRASARTLRSARTRVLALAAPRVPGAYRAVDGRFAIDVTDAARVHGYDVLLMTDSDGV
                     AGLRRVARSRLADAAVLMAVEDRDPRVEVLRELGFPGALLGHDDHAALPWTDLDWDAAV
                     ALAVRETAAAGHRRILFLSSAEHEVAARRGYALHGLAGARRAAVETGADVRVIPSHCDP
                     DVLARRLSEALAARPVPTALVVQHLILLPRLLDVVAAAGLRVPHDLTVVLVGSLPDELG
                     IRHLPRIDLPVAEMSTAVTRLAIGAIGPGLDDRSSTSQELTAAPASSMPSGTPHHVIQP
                     RMAGPVIAPPSPS"
     gene            4679..5944
                     /locus_tag="SCNRRL3882_RS00960"
                     /old_locus_tag="SCNRRL3882_0189"
     CDS             4679..5944
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995241.1"
                     /locus_tag="SCNRRL3882_RS00960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0189"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_029181683.1"
                     /transl_table=11
                     /translation="MPLLAGRIRTRRGRVPALAATLAATLACAVVAPWLTGCAAEPDPG
                     TVTVLNSATDTAEHTANQRFFDRCGKPLGLKVEQISVPADQIASKALRMASSDSLTDIL
                     ELDGSELPQFAQTEGLRPLDEVGVDTSGLSASAKSLGSYDGTQYGIARSVNSLALIYNT
                     ELLEDAGIAAPTTWKELRAAAKKLTAGDTYGMAFSASPNADGVYQFLPFFWSAGGDETE
                     IDNGRGEAALQLWKDLVADGSASRSVVNWNQQDVNDQFVAGRAAMMINGPWQVPVLNAQ
                     KNLDWAVASIPVPEAGKPAVPPIGGTVMAVPKNDEDPAREKNAGKVLNCLNSEENQLQW
                     GESVNNVPTRAKAAQAYAKQNPKLAAFAELVTTARSRTAKVGTGWPAVGDALAGAFQSV
                     LTGRTSPEQALHRAQQQASTGK"
     misc_feature    4688..4690
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5955..6914
                     /locus_tag="SCNRRL3882_RS00965"
                     /old_locus_tag="SCNRRL3882_0190"
     CDS             5955..6914
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432647.1"
                     /locus_tag="SCNRRL3882_RS00965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0190"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_010047199.1"
                     /transl_table=11
                     /translation="MTAITSSAPATGTAETKSASGRAPLRRELLRWLFVAPALAYMALF
                     FGYPLVRNIVMSFQHYTPKTYFTGEAPFNGFDNWRAVFANELFTDALWHTALFTVGSLL
                     GQFTVGLALAVFFSRRFPLSGFVRAILLLPWLVPMVVSAVVWRRILDQDHGMLNTALHA
                     VGLVPQDGVPWLSSPGVALLSAVLVNIWIGIPFNMVILYGGLQEIPRDLYEAASLDGSG
                     PWRTFRSITLPMLRPVITVVLVLGFMSTVKILDLILALTSGGPADSTQTLGTVTYQLSF
                     LQLDFGQGAVVGNVLILISAVFAVLYLRANRADFGKGK"
     gene            7041..7772
                     /locus_tag="SCNRRL3882_RS00970"
                     /old_locus_tag="SCNRRL3882_0191"
     CDS             7041..7772
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063913.1"
                     /locus_tag="SCNRRL3882_RS00970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0191"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_231911214.1"
                     /transl_table=11
                     /translation="MLNTALQPESSIAATEWFPLSPSLKNFDTAISTQGGSLLTSLGVA
                     LGAVAVCLALAAPAAYGLAQFGLRGGQGIVFATLITQMVPGIVIANALYSAYAQLDLVN
                     SYLGLILADASLGLPFAVVLLRAFMVSIPSEVVEAAMVDGANRFTAFVRIVLPMSRNAL
                     ITAGLFTFLFAWSDFMFALTLNTTDDVKPITLGIYQFVGAHVSDWGAVMATAVLSAVPA
                     AVLLVVAQKYIAAGITGGSVK"
     gene            complement(7875..8039)
                     /locus_tag="SCNRRL3882_RS40645"
     CDS             complement(7875..8039)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SCNRRL3882_RS40645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158688461.1"
                     /transl_table=11
                     /translation="MFALIAGRFQGLCPRRFVVTDAGVINAVCPGVIDTPMVADMGTAL
                     PVDGGFTAH"
     gene            complement(8104..9996)
                     /locus_tag="SCNRRL3882_RS00975"
                     /old_locus_tag="SCNRRL3882_0192"
     CDS             complement(8104..9996)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986676.1"
                     /locus_tag="SCNRRL3882_RS00975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0192"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_010047205.1"
                     /transl_table=11
                     /translation="MSTAPLVETPPGPGSRAGSGAHEDPGGFRPGYRALAGQLRGQRGR
                     MAAGVALGLMGSVMGLVQPLAAKRVMDDMSLGQPAAGPVIVLSLLVIAGALFVGLSHYV
                     LQWSAESIVCAARCRLTDRLLRLRVPVVESTEPGDLIARVTSDTALLLQTAPQAMSAAV
                     TGTLATAATVVMMGLLDAVLLSVTLAVIAFVGVIVTVVAPRIGRATRHTQESVGHIGAA
                     LERVFGAFRTVKASGAEQRETAALHRAAEDARRTGVRAAAWEAVSATSSAVVFQVSFLV
                     VLGVGGTRVTSGAISISTLVAFLLYLFTLAPRIGQLVEGVGQLQVGSAAAVRIGEVEKL
                     EIEKLEAEQVGEGDTTVHDGERTGAAEADSAAPDTSLTTTSERAGSPLGVAFHRVCFVY
                     RPGLPRIHQEVSFSIPARGLTAFVGPSGAGKTTVFSLIERFYEPDSGRVLLDGRDVQQW
                     PLSRLRASIGYVEQDAPVLAGTLRDNLTLGTVEPTSEELARILRLARLDTVADRLPRGL
                     DSDVGHRGSRLSGGERQRVAIARALLRRPGLLLLDEATSQLDAANEAALRDTITETALD
                     TTVLVVAHRLSTVTRADRIVVMEAGRVRAVGTHAQLMTGDALYSELASTQLLSQ"
     misc_feature    complement(8116..8118)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8368..8370)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..10471)
                     /locus_tag="SCNRRL3882_RS00980"
                     /old_locus_tag="SCNRRL3882_0193"
     CDS             complement(10001..10471)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="SCNRRL3882_RS00980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0193"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_324604471.1"
                     /sec_met_domain="PF13471 (E-value: 3.5e-23, bitscore: 80.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVQAVCPAPSVQTGEPRMSTSEAVPYRPRSVPPARRFLARVVVC
                     CAHVLATQPPDRIRAVLRRLRRGARPATLAEASTARETVLAVSLAAGGHKGCLSRSLAT
                     VLLCRVYGQWPTWCVGVRSRPPFAAHAWVEAEGVLVGEGASPDYFRRFFAVE"
     gene            complement(10531..10788)
                     /locus_tag="SCNRRL3882_RS00985"
                     /old_locus_tag="SCNRRL3882_0194"
     CDS             complement(10531..10788)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986678.1"
                     /locus_tag="SCNRRL3882_RS00985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0194"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_010047209.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.1e-21,
                     bitscore: 73.7, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.4e-13, bitscore: 47.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFALKPGVLMTETEYGMALLDQRSTEYWTLNPTAAIVLQALLDGH
                     GAERAVEVLTTRYENVDVDRATEDVRRIVEELCSAGLLIS"
     aSDomain        complement(10540..10788)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SCNRRL3882_RS00985_Stand_Alone_Lasso_
                     RRE.1"
                     /evalue="1.40E-23"
                     /identifier="RREFam002.1"
                     /label="SCNRRL3882_RS00985"
                     /locus_tag="SCNRRL3882_RS00985"
                     /protein_end="83"
                     /protein_start="0"
                     /score="73.7"
                     /tool="antismash"
                     /translation="MFALKPGVLMTETEYGMALLDQRSTEYWTLNPTAAIVLQALLDGH
                     GAERAVEVLTTRYENVDVDRATEDVRRIVEELCSAGLL"
     gene            complement(<10904..12742)
                     /locus_tag="SCNRRL3882_RS00990"
                     /old_locus_tag="SCNRRL3882_0195"
                     /pseudo=""
     CDS             complement(<10904..12742)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_053804306.1"
                     /locus_tag="SCNRRL3882_RS00990"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0195"
                     /product="asparagine synthase-related protein"
                     /pseudo=""
                     /sec_met_domain="Asn_synthase (E-value: 1.2e-32, bitscore:
                     112.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQSLSLQAVSAWFVVLPDTDAAGALAAKALCYSDRSLPHASGRP
                     WLVGRWAPETVVMAEHGGTRVAVIGEHAVTARDAERAAAAADGAASLTAVDRAADWPGS
                     FHLIVSGGGRVRMRAGAVDLRRVFHARTGTPGHGPVSVASDRADVLAELVGAELDERRI
                     ALELLTLGAPYPSAGDPLWRGLQAVPGGHCLTLHPDGRTCTMRWWSPPDPVVPLAIGAA
                     RLREALTEAVEVRTRGRDLVTSDLGGLDSTALCCTAARGGAKVVAYTAALHDEAGDDVY
                     WAERTVQALNGIEHHVVPAQKVAMTFLGIDALEDVLDTPSILTVDRNRRMGIVELAAAR
                     GSGLHLIGLGGDELLAGTPARLHTLLLTHPLIAVQAVRGYAAKYRWSRRRVLRQLLDRS
                     PYRAWLDQVARDLTEPAVPDNEPLLGWAIPPRMPPWATPDALTAARELLRAARSEVRPR
                     GRGHGEHRELVAMDGISQVARHIGQMAAPLGIAVSAPYYDTRVIEAALAVRPQERITPW
                     CYKPLIVEAMRGIVPEASRSRDTKANATLEEEAGLREHRRALLALCEDSRLARLGLVDE
                     RVLREWCRRALSAEKESYLLHPTIACEVWLRSREMTP"
     misc_feature    complement(12188..12190)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12881..12988)
                     /locus_tag="SCNRRL3882_RS40650"
                     /old_locus_tag="SCNRRL3882_0196"
     CDS             complement(12881..12988)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039305.3"
                     /locus_tag="SCNRRL3882_RS40650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0196"
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_158688462.1"
                     /transl_table=11
                     /translation="MTYERPTLTKAGSFRKVTGIKNTGPKDVLGGKQLL"
     misc_feature    13159..13175
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.41"
                     /tool="antismash"
     gene            <13525..13842
                     /locus_tag="SCNRRL3882_RS00995"
                     /old_locus_tag="SCNRRL3882_0197"
                     /pseudo=""
     CDS             <13525..13842
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981556.1"
                     /locus_tag="SCNRRL3882_RS00995"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0197"
                     /product="IS701 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="WHREERRHWVLARRSVSRPEEISHYVAYCPADTTLDELIRIAGSR
                     SAVEEWFQTGKQECGLDDYRVRRYPGWRRHITLAMPAHARLTGRRPTPQRPHPALVDMA
                     P"
     misc_feature    complement(14416..14429)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.67"
                     /tool="antismash"
     gene            14691..>14880
                     /locus_tag="SCNRRL3882_RS42345"
                     /pseudo=""
     CDS             14691..>14880
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018385630.1"
                     /locus_tag="SCNRRL3882_RS42345"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAAFLYRIGRWAFRRRRLVGGLWLGGPGGAGRRRCRRGAGGGGRG
                     PLHARRRVSEGVRFAGRA"
     gene            14898..16294
                     /locus_tag="SCNRRL3882_RS01010"
                     /old_locus_tag="SCNRRL3882_0198"
                     /pseudo=""
     CDS             14898..16294
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173212.1"
                     /locus_tag="SCNRRL3882_RS01010"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0198"
                     /product="MFS transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSEAVVSPARIGWLPIGVLGILALALGTLQSVVEPALPLLQRELG
                     VSPSEGALIGNALLITGAVITPVAGKLGDRYGGKRVLVRLMGVVSVGGLMASLAPNLPV
                     LLVGQVLQGVMVGALPLSFILVRKHLTAGESQAAIGLVVALFTGGGMVGTLCAGPIAEG
                     LSWQWMFALPTIAIIATTLGVTRLMPHDPPIQSDDGIDWPGTVLLSGTLLAFMLGLVTV
                     TRDGGVPSLAVGAIAVVVVALASGWVVVERRAASPMVDLRMLAKPAMWNACVLTFVMTA
                     SSGMVLFSSRSCSRYRPRGTDSEPAPPTSDCSCCPAPSPGR"
     misc_feature    15069..15071
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16291..17520
                     /locus_tag="SCNRRL3882_RS01015"
                     /old_locus_tag="SCNRRL3882_0200"
     CDS             16291..17520
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173213.1"
                     /locus_tag="SCNRRL3882_RS01015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0200"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_010047214.1"
                     /transl_table=11
                     /translation="MTSTGLSMDVSTTAKRTVLISGASISGPALAYWLHRSGFAVTVVE
                     KAGALRDGGYPIDVRGTAIEVVRRMGILPHLQDAHIDSRRFTFLNADGSEVASLTPRAV
                     AGGVEGQDLEVRRGDLAANLYAIVRDDVEFLFGDSIDTLDQSERGVEVRLHSGQRRTFD
                     LVVGADGMHSHTRESLFGPEEQFHRYLGYCFAIFTMPNTFGLARELVLWNTPGKAAALY
                     AVGDNDELHAFLNFHQPEPPVDALRDPDAQRDLVATIFAGAGWEVPGLIQAMRDADDLF
                     FDTAGQIRMPHWSSGRAALVGDAAYAPSFLTGQGTSLALVGAYMLANALATHRDYTAAF
                     AAYERDMREFVAMNQALVDNGAATLFPTTVRALEQRNTILRDLVTMPSASARPAHSALT
                     LPEFAADAVT"
     gene            complement(17881..18573)
                     /locus_tag="SCNRRL3882_RS01020"
                     /old_locus_tag="SCNRRL3882_0201"
     CDS             complement(17881..18573)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018853056.1"
                     /locus_tag="SCNRRL3882_RS01020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0201"
                     /product="response regulator transcription factor"
                     /protein_id="WP_010047219.1"
                     /transl_table=11
                     /translation="MTLRVLLADDQALLRGAFRMLLDSADDITVVGEAADGREAVRLTR
                     ELRPDVVVMDIRMPEVDGLTATSEICADPELRASRILILTTYETDEYVAQALRAGAGGF
                     IGKGIGAEDLLDAVRTIADGDTLLSPAATRSLVARFLATPEVVSPHHSEQLAALTPRER
                     EMVAAVATGLSNQEIAERMFLSPFTVRAHVQRAMTKLEARDRAQLVVIAYRTGLAQAGP
                     AGGADRLS"
     gene            complement(18570..19895)
                     /locus_tag="SCNRRL3882_RS01025"
                     /old_locus_tag="SCNRRL3882_0202"
     CDS             complement(18570..19895)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059630.1"
                     /locus_tag="SCNRRL3882_RS01025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0202"
                     /product="sensor histidine kinase"
                     /protein_id="WP_010047221.1"
                     /transl_table=11
                     /translation="MTKPGGGGPRPRGAWWREAAITATAFAFCLLGGVIQVDDTLSAPP
                     AAAYVVAVVSCAVLPVRHRAPLAALTATTAVGVLVPPLGLLLTPLIVAPVVITAYSYAL
                     AARTERRAASAVLLTSTVLVASIPLFGDFSWKDASRMAVVAVFPLVAGVLGHSVQNRRA
                     YLAAVEERARRAEQSRDSEARRRVAEERVRIARELHDLVAHQITLANAQATVAAHLFDT
                     RPEQTRMSLKELVETTADALDDLRATVGLLRQSGDAATPAEPAPGLSRLSTLLESFRRA
                     GLEVSVQQEGTARPLPPGVDLTAYRIVQEALTNVTKHAGTGSARVHLVWNRDRVTITVA
                     DDGQGSGTAPTASTGPGASTAADRPPGYGLIGMRERATAVGGHLSAGRRPEGGFLVSTQ
                     LPLPPAKGTTRRTDGATTIEGRMGDGGSGNGRTGDGDTRDAP"
     gene            complement(19903..22146)
                     /locus_tag="SCNRRL3882_RS01030"
                     /old_locus_tag="SCNRRL3882_0203"
     CDS             complement(19903..22146)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018385630.1"
                     /locus_tag="SCNRRL3882_RS01030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SCNRRL3882_0203"
                     /product="MMPL family transporter"
                     /protein_id="WP_010047224.1"
                     /transl_table=11
                     /translation="MATFLYRIGRWAFRRRRLVGGLWLGVLLLAIGAAAMAPTGEEEDL
                     SMPGTESQKAFDLLDERFPQSNSQGAEARLVFQAPDGQRVTARENKAAVEDTLGSLDGG
                     DQVASTTNPYETGAVSEDGTIAYSTITYTADAVDLTQPTKSALEDAASRARDAGLTVEI
                     GGSALDAEEEPGGTTEIIGVAVAAVVLVLALGSLVAAGLSLLTALVGVAIAFGLVSALA
                     VPLGLTSTVAILALMLGLAVGIDYALFVTSRFRDERARGSEPEEAAGRAVGTAGSAVVF
                     AGATVFIALAGLGVVGIPELTKMGMGGAGAVALAVLVALTLVPALFGFFGRRVLSRAVR
                     KTTRPGSERPHRVPTAVGRPGLGTRWARFVLRRPVPVLLIAGLGLGAVALPALSLELGL
                     PGDESKSVETTQRRAYDLLSQGFGPGFNGPLTVVVDTSESADPRATSELVVKTVRGVDG
                     VASVGEPVLSRSKDTAVLTAVPQTAPNSGETKDLVHAIRGAVLGVEADTGAAILVTGTT
                     AMNIDISEAMSDALIPYLTVVIGLAVLLLTVVFRSVLVPVKAALGFLLSVGAAFGVLVA
                     VFQWGWAADLVGIEQTGPVMSLMPILIIGIVFGLAMDYEVFLLTRMREAYAHGACPGEA
                     IVNGFRHSGRVVAAAAIIMISVFAGFIGMSSPTIQTMGVGLAAAVAFDAFVVRMAIAPA
                     VLALLGHRAWWLPRILNRVLPNVDIEGEALSRHVPVSATGPNAAVRRLPVGRD"
     misc_feature    complement(22537..22550)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.16"
                     /tool="antismash"
ORIGIN
        1 gaggaccgcg gtcacctcgc gtaccgactc ctcggggatc accgacccga tccgcagttc
       61 cagctcctcc tcgaagacct tcagcgcccc gtccaccagc ttccgcccct caggggtgag
      121 ctcgacgatc gaggaacggc ggtcgttcgg attggccttc cgaccacaca gccccgccgc
      181 ctccagacgg tcgacgacct tgctcgtgcc gcccaccgtg atcgagaact cctccgcgat
      241 gtcctggatc cgccgcccag gccacctcaa cagcaggtgc agcacctcga acgaggtcag
      301 cgccaggtcg tactccgccc gcaaccgctc ctcgatgccg ccccacaact cgatctccag
      361 cgagaccagc tcccggtaca gcagcttcag gtcagcgtca gccattactc atcttccaaa
      421 gaattatctt ccatagacag ttaattgtag gtcaccgcta tcgggactct ccacgaatgc
      481 cgggtgtacg taccgacgtg gacgggatga agccaagatc tcagccggtc gtcggtggca
      541 agggcctgtg ctatgggccg agcgtggccc gtcgagcgcg ggtgtcacga ggtcgcctcc
      601 tgggtggtgc ggtaacggtg atgctgggcg gcgatgtcgc ggtggcgcag gcgtgcggcc
      661 agcggtggcg gggtgagggg cgagtctgct tggtgttcca gcgtcgcggc ctgtgcgagt
      721 ccgccgttgc caccgtgctc aacaagcagg acaagaagaa gctcgtcctc gcccccgccc
      781 gcgccgcgcg aacctggttg gccatgcacc ggcaccgctg gcacacccgc caccagatcc
      841 tggcccgaac cagccactac caagcccgag ctgcacggac tcactcaccg tgaaaccacc
      901 ggccgtcaca ctagtggtgc caagctcgcc cgcccgtgtt gtggatgaac cgctgcaaca
      961 ccttgagggt ggtcaggtac tcctcgtcgg agatacccgc atgccgttcc gcccagagct
     1021 cgtcctgaag ggccgcggcc ttgtcgtaga acgccctgcc ctcagccgtg aggcccaggc
     1081 gcccctcggc atcctcggtg atccagccct gggcgatgat cgtatcgatc tccgactcca
     1141 tggtttccgg gccgacgtcg aggtagttcc gaaggaggcg ggacacttcg tcacgggtct
     1201 tcacgttgtc ggcgcttgcc acctgcgcga ggacccacca ctgcggttgg gtggtgccga
     1261 tcccggcgag ggcggcccgg gtgcgggcga tgacagcctt gtaggccgcc caactccagt
     1321 agccgatggg ctgcttgatc aggtcggtgt cgctgtgcga gtactccatg gccaggatcc
     1381 ctgtcgttgt ctgagtcggt ccgacgagat cgaccgtaga aactcaactg gacttgaggt
     1441 caagggtgta ccggtcgagt cgtccgagaa ggcctagttg ctactcactc accgcgagac
     1501 caccggctgt agtaccagcc gccctgctgg cccgctcaac agcgacctgt gtccatgccg
     1561 gcaagcccga atgcccgtgc ccaaggagac gccggtaatg ccctgcaagg gcggctccgg
     1621 gccttcgaac ggcgcatcac tgccctaggg gtctgagcca aaggcagctc agggcccacg
     1681 caggctctgt gacggggccg gtgacggctt gccgagcaac cgctcaccag cacgtcgacg
     1741 atcgccgcga acagcgtctc atcaggcgtg tcctgcgtcc cgccccctgc ggacgcatcg
     1801 tcggtggaag gatcaacggc ttcgcgatct cccacagtcc gtccggaacg atccaactcc
     1861 atcttctacg ccccgtaccg gcgtcaacga ccgcctcacc acgaaggaca cactcttact
     1921 cccctggacc cgcaaccgtg aaaggtccca cagcggaggc gacacacgcg gagatgtccg
     1981 tttccacgcc cgccgccaag ccctcctcac agagacggcc tcccctctcg cgcaggtcca
     2041 ggtagaagcg cgtgaacttg ccgtcctgcc tgaggccgtg gatgcgttcg tcgatgtaac
     2101 caaggtcgtt caggaccttc ctgacctttg caggggtggg ctccgaaacc gcctgcagcg
     2161 cctggccgat gcgctgttcg tgctggacgc tcatgcaccg gtctcggtcg ttcagttccg
     2221 cctcggggcc cgtgggggcg ccaggctcga tcgggacagc cggaggggtc tcgccggggg
     2281 cgaggctctc cctcccctcc ttccccgagc cggttggcct cttgtgagac gggcctgact
     2341 cggtctcggt ctgggtctcg gactcgctct caagacacgg ctgcgcaacc ttgtgcagca
     2401 tcgccatgaa ccccgcctgc tcaggctccg acgatgtggc actctcagcg gcgctgacgc
     2461 tgctggccgg cttgctctca gacccaccgt cactcgggct ctcgctccca cagccggcaa
     2521 gcaccaaggt cgcgagcgcg gttgccgtca gggcacgtcg ggggcggaca agtgggctga
     2581 tggaagcgga gatccgtgtc atgggcgcag tctccggccg gcgtcgcgcg ccccgcatga
     2641 gtgtgcgtac tcatatacac aatcactcac ggaacgtggc tgtgagatct tcctacgcct
     2701 catccgcctc accacgtagg acacggcctc agacaggtca gcccctgggc gctggtaatg
     2761 cgcctgcttg acgctcctgg ttcagttcag gctcgctgtc gccatccgtt cggacctgcc
     2821 tcggaaacag cgccctgcga tgcggcagcc agtgatccgg agcacgccac gcctgcggtc
     2881 ctgtcacttc gaacagcctc cgcagctgta cggtaacggg tggtcgaccg tgccgtacct
     2941 gaggtccagc cgtccggaaa tgcgcgcacc cgtcagcttc aggcctgcga tcccaccgtc
     3001 gcgcgccggc ccgccgacca gcagcgcccg caggtgatct ccatcagcgg gatgctggcg
     3061 cccgcctgat cacgctgaca actcggcacc ggtaacacgc ccttccagcg gtgcgttgcc
     3121 agcccgaccg gtgttcagag gcgggtacag gtgtgaacgc ggatctgcta cctcggcggc
     3181 gttctctccg gacggccgcc tcctctccac cgtcggcgac gacacgaccg tgcgcctgtg
     3241 ggagcggccg ggcgacccgt tccccttgat gcggcgtgcg ctgctgccgc tcgcggcacg
     3301 aactcactgg tatgacgggc cgtcggagaa gtgttctccc gggtccatat ggtggtcgtg
     3361 ggcggcaaca acgtatcggt gttcacggcc cgcggtctgc tccacgttca aggtattgcc
     3421 ctccccaacc caccgtgctt aaggtcaccc cgcttgtcga atcgattcga tcgattcgat
     3481 cgatgcgaca gagccgacga atcccgagac gggcctggtg gaggtgggga tgaccacgat
     3541 caaggacgtc gcccagcggg caggcgtcgc gccgagcacc gtgtcgtacg tcctgagcgg
     3601 gtcgcgcaag atctccgagg acacccgacg cgcggtgcag gtcgcgatcg acgagctcgg
     3661 ataccacccg cgcgcgagtg ctcgtacgtt gcgcagcgca cggacccggg tgctcgcgct
     3721 ggccgcgccg cgtgtgcccg gggcgtaccg ggcggtcgac ggtcggttcg cgatcgacgt
     3781 caccgacgcc gcccgtgtgc acgggtacga cgtgctgctg atgacggaca gcgacggtgt
     3841 cgctgggctg cgccgggtgg cccgcagcag gctcgcggac gccgcggtgc tgatggccgt
     3901 cgaggaccgc gacccccgtg tcgaggtcct gcgcgaactg ggcttccccg gggcgctgct
     3961 cggtcacgac gatcacgcgg cgctgccctg gaccgacctg gactgggatg ccgccgtcgc
     4021 cctcgccgtg cgcgagaccg ccgctgccgg acaccggcgg atcctcttcc tctcgtcggc
     4081 cgagcacgag gtcgccgcgc gccgcggcta tgccctgcac ggtctcgccg gcgcccggcg
     4141 ggcggccgtc gagaccgggg ccgatgtccg cgtgatcccg tcccactgcg acccggacgt
     4201 cctcgcgcgg cggctgagcg aggcgctggc cgcgcggccc gtcccgaccg cgctggtcgt
     4261 ccagcacctg atcctcctcc cccgcctgct ggacgtggtg gcggcggccg ggttgcgggt
     4321 cccccacgac ctgaccgtcg tgctcgtcgg cagtctcccg gacgagctgg gcatccggca
     4381 tctgccgcgg atcgatctgc ccgtcgcgga gatgtccacg gccgtgaccc ggctcgccat
     4441 cggcgcgatc ggtcccggcc tcgacgaccg gtcatcgact tcgcaggagc tcaccgcggc
     4501 acctgcctcg agcatgcctt ccggcacgcc gcaccacgtg atccagccgc ggatggccgg
     4561 acccgttatc gccccgccgt cgcccagctg accatttgga ccgcccgtac ggcacggccg
     4621 gcgacgcacc gtcgtcggac accgcagtcc agagccgcac atgtaacgga ggaccgcctt
     4681 gccgttgtta gcaggacgca tcagaacaag acgcggacgc gttcccgcac tcgccgccac
     4741 gctcgccgcc acccttgcct gtgctgtcgt cgcgccatgg ctgaccggct gcgccgcgga
     4801 gcccgacccg ggcaccgtca ccgtgctcaa ctcggcgacc gacaccgccg aacacaccgc
     4861 caaccagcgg ttcttcgacc gctgcggcaa gccgctcggc ttgaaggtcg agcagatcag
     4921 cgtgcccgcc gaccagatcg cctccaaggc gcttcggatg gcgtcgtccg actcgctcac
     4981 cgatatcctg gagctcgacg gctcggaact gccccagttc gcgcagaccg agggcctgcg
     5041 gccgctcgac gaggtcgggg tcgacacctc cggcctctcc gcgagcgcga agtccctcgg
     5101 ctcgtacgac ggcacccagt acggcatcgc ccgttccgtc aactccctcg cgctgatcta
     5161 caacaccgag ctcctcgagg acgcgggcat cgccgcgccc accacctgga aggagctgcg
     5221 ggccgccgcg aagaagctga ccgcgggtga cacgtacggg atggccttca gcgcgagccc
     5281 gaacgcggac ggcgtctacc agttccttcc gttcttctgg tccgcgggcg gtgacgagac
     5341 cgagatcgac aacggcaggg gcgaggccgc tctccagctc tggaaggacc tggtcgcgga
     5401 cggttccgcc tccaggtccg tcgtcaactg gaaccagcag gacgtcaacg accagttcgt
     5461 cgcgggccgc gccgccatga tgatcaacgg gccgtggcag gtgccggtcc tcaacgccca
     5521 gaagaacctg gactgggcgg tcgcgagcat tccggtgccc gaggcgggca agccggcggt
     5581 gccgcccatc ggcggcaccg tcatggccgt accgaagaac gacgaggacc cggcccgcga
     5641 gaagaacgcc ggcaaggtcc tgaactgcct caactccgag gagaaccagc tgcagtgggg
     5701 cgagtcggtc aacaacgtgc ccacccgcgc caaggccgca caggcgtacg cgaagcagaa
     5761 cccgaagctc gccgccttcg ccgagctcgt caccaccgcc cgctcccgta ccgcgaaggt
     5821 cggcaccggc tggccggccg tcggcgacgc gctcgcgggc gctttccagt ccgtgctgac
     5881 gggccggacc agtccggaac aggccctgca ccgggcccag cagcaggctt cgacagggaa
     5941 gtgaggaacc ggccatgacc gccatcacct cctcggcgcc cgccacgggc accgctgaaa
     6001 cgaagtccgc ctccggccgc gctccgctgc gccgcgagct gctgcgctgg ctcttcgtcg
     6061 ctcccgcgct cgcctacatg gcgctcttct tcggctaccc gctcgtccgc aacatcgtga
     6121 tgagcttcca gcactacacg ccgaagacct acttcaccgg cgaagccccg ttcaacggct
     6181 tcgacaactg gcgggccgtc ttcgccaacg agttgttcac cgacgccctg tggcacacgg
     6241 ccctgttcac cgtcggctcg ctgctcggcc agttcaccgt cggcctggcc ctcgccgtct
     6301 tcttctcccg ccgcttcccg ctctccggct tcgtgcgcgc catcctgctg ctgccgtggc
     6361 tcgtgcccat ggtcgtctcc gccgtcgtct ggcggcgcat cctcgaccag gaccacggca
     6421 tgctgaacac cgctctccac gcggtcggcc tggtcccgca ggacggcgtg ccgtggctga
     6481 gcagccccgg cgtggcactg ctgtcggcgg tcctggtcaa catctggatc ggcatcccgt
     6541 tcaacatggt catcctctac ggcggcctcc aggagatccc gcgcgacctg tacgaggccg
     6601 cgtcgctcga cggctccggc ccatggcgga cgttccgcag catcacgctg ccgatgctgc
     6661 gaccggtgat caccgtcgtg ctcgtgctgg gcttcatgtc gacggtgaag atcctcgacc
     6721 tgatcctggc actgacctcg ggtgggcccg cggactccac ccagaccctg ggcaccgtca
     6781 cgtaccagct ctccttcctt cagctcgact tcggccaggg cgccgtggtg ggcaacgtcc
     6841 tgatcctcat cagcgcggtc ttcgccgtgc tgtacctgcg ggccaaccgc gccgacttcg
     6901 gcaaggggaa gtgaccgtcg atgaaccgac cgatgaaccg accggtgacc cgaccggtga
     6961 accttctccg cgttcgttcg gtgtggaaca ccgccgccgc gctgctgatc ctcgccgtgc
     7021 tcctcttccc tgtgtactgg atgctcaaca ccgcccttca acccgagtcg agcatcgccg
     7081 ccaccgagtg gttccccctc tcgccgtccc tgaagaactt cgacacggcg atcagcaccc
     7141 agggcggctc gctgctcacc agcctcggcg tcgcactcgg cgccgtcgcc gtctgcctcg
     7201 cgctcgccgc gcccgccgcg tacgggctcg cccagttcgg actccgcggc gggcagggca
     7261 tcgtcttcgc gacgctgatc acgcagatgg ttccgggcat cgtcatcgcc aacgccctgt
     7321 acagcgccta tgcgcagctc gacctcgtca actcctatct ggggctgatc ctggcggacg
     7381 cctcgctcgg tctgccgttc gcggtcgtac tgctgcgggc gttcatggtg tcgatcccga
     7441 gcgaggtcgt cgaagccgcc atggtggacg gggcgaaccg cttcaccgcg ttcgtacgga
     7501 tcgtgctgcc catgagccgc aacgccctga tcacggcggg actgttcacc ttcctcttcg
     7561 cctggtcgga tttcatgttc gcgctcaccc tcaacaccac tgacgacgtc aagcccatca
     7621 cgctcggcat ctaccagttc gtcggcgcac atgtcagcga ctggggcgcg gtcatggcga
     7681 ccgcggtgct ctccgccgta ccggccgcgg tcctgctcgt cgtcgcccag aagtacatcg
     7741 ccgccgggat cacgggcggg tcggtcaagt agggcggtta tgtttctccg tccggggcgc
     7801 cgtcgtcggt ctgatcgagt gatcgagttc aaaggggcgg gcgtatcgcc agggcgtgcg
     7861 tcagtgaacg gacatcagtg cgcggtgaag ccaccatcga cggggagagc tgttcccatg
     7921 tcggcgacca tcggggtgtc gatgacgccg gggcacacgg cgttgatgac gcccgcatca
     7981 gtcactacaa aacgacgcgg acacagcccc tgaaaccgtc cagcaatcag tgcaaacacc
     8041 gttgtgaggg tgtgcctcga tgagctggag ttcgtcgagg aacaccctcg gcgggggtcg
     8101 cggttactgg ctgagtaatt gtgtgctcgc cagttcgctg tagagagcgt cacctgtcat
     8161 gagctgggca tgggtgccga ccgcccgtac tcgtcccgcc tccatgacca cgatccggtc
     8221 cgctctggtc acggtggaca ggcggtgagc gactaccaac actgtggtgt caagggcggt
     8281 ttcggtgatg gtgtcgcgca gcgccgcctc gttggccgcg tcgagctggg aggtggcctc
     8341 gtcgagcagc agcagtcccg ggcggcgtaa cagggcgcgt gcgatcgcca cgcgttgccg
     8401 ttcgccgccg gagagtcggc tgccgcggtg gccgacgtcg gagtccagtc cacggggaag
     8461 gcggtccgct accgtgtcca ggcgggccag ccgcaggatg cgggcgagtt cctcgctggt
     8521 gggctcgacg gtgccgaggg tgagattgtc gcgcagggtg ccggcgagga cgggggcgtc
     8581 ctgctcgacg tagccgatgg acgcgcgaag ccgggacaga ggccattgct gcacgtccct
     8641 tccgtccagg agcacgcgac cggaatcggg ctcgtagaag cgctcgatca gggagaagac
     8701 cgtggtcttg cccgcgccgg acgggccgac gaaagcggtc agcccgcgtg cgggaatgga
     8761 gaaggagacc tcctggtgga tgcggggcaa tccggggcgg tagacgaagc acacccggtg
     8821 gaacgccacg ccgagcggcg atccggcgcg ttcggaggtc gtggtcaagg aggtgtccgg
     8881 ggcggcggaa tccgcctcgg cagcgccggt tcgctcgccg tcgtggactg ttgtgtcgcc
     8941 ttcccccacc tgctccgctt ccagcttctc gatttccagc ttctcgactt ccccgatgcg
     9001 gacggccgct gccgagccga cctggagctg accgacgcct tcgaccagtt ggccgatgcg
     9061 cggagccagg gtgaagaggt agaggaggaa cgcgacgagg gtggagatgc tgatggcgcc
     9121 ggaggtgacg cgtgtgcctc ccacgccgag caccacgagg aagctgacct ggaagaccac
     9181 cgccgacgac gtggccgaca ccgcttccca cgccgcggcg cgtaccccgg tgcggcgggc
     9241 gtcctcggcc gcccggtgca gcgccgccgt ctcccgctgc tcggcgcccg aggccttgac
     9301 cgtgcggaaa gcgccgaaga cccgctccag cgcggccccg atgtgaccta ccgactcctg
     9361 tgtgtgccgg gtggcgcggc cgatgcgtgg ggccacgacc gtaacgatga cgccgacgaa
     9421 ggcgatcacg gcgagggtga cggacagcag cacggcatcg agcagtccca tcatgacgac
     9481 agtcgccgcg gtggccagcg tgccggtgac cgccgcggac atcgcctggg gcgcggtctg
     9541 gagcagcaac gccgtatcgg aggtcacgcg ggcgatcaga tcgcccggct cggtgctctc
     9601 caccacgggc acccgcagtc gcagcagacg gtcggtcagc cggcaccggg cggcgcacac
     9661 gatggactca gccgaccatt gcagcacgta gtggctcaga ccgacgaaga gggccccggc
     9721 aatcaccagc agactgagca caatcaccgg tccggccgcg ggctgtccca ggctcatgtc
     9781 gtccatcacg cgcttggctg ccaaaggctg gaccaggccc atgacgctgc ccatgagtcc
     9841 cagggcgaca cctgcggcca tccgcccccg ctgcccacgc agctgacctg cgagggcccg
     9901 gtacccgggc cggaagccgc ccgggtcctc atgtgcaccg gacccggcgc ggctgccggg
     9961 tccgggaggc gtctcgacga ggggtgccgt gctcatcggc tcactccacc gcgaagaagc
    10021 gccggaagta gtcaggcgag gctccctcac cgacgaggac cccttcggcc tccacccaag
    10081 cgtgtgccgc aaacggcggg cggctacgca ctcctacaca ccaggtgggc cactggccgt
    10141 atacacggca cagcaggacg gtggccaggg acctggacag gcatcccttg tggcctcctg
    10201 cggcgaggct cacggcgagc actgtctcgc gtgccgtgct tgcctcggcg agggtcgcgg
    10261 gcctggcgcc gcggcgcagc cgacgcagga cagcgcggat acggtcgggc ggttgcgtgg
    10321 ccagcacatg ggcgcaacac acgaccaccc gggccaggaa acggcgggcc ggtgggacgg
    10381 agcgtgggcg gtacgggacc gcctccgacg ttgacatgcg tggctctccg gtctggacgg
    10441 acggggctgg gcagacggcc tgtacggcca tagccgaagg acggatcagg cggacgcatg
    10501 gattgcgcac cgacaggccg ggattggggc tcaagagatg aggagtcctg cggaacacag
    10561 ctcttcgacg atgcggcgga cgtcctcggt ggcccggtcg acgtcgacgt tctcgtaccg
    10621 tgtggtcagg acctcgactg cgcgctccgc gccgtggccg tcgaggagcg cctgcaggac
    10681 gatggcagcg gtcgggttga gggtccagta ctcggtgctc cgctggtcga gcagtgccat
    10741 gccgtactcg gtctcggtca tcaggacgcc gggcttcagg gcaaacaccg gttcacctct
    10801 ctcggttctc tcggttggcg gcggacagag ccgcggatac agaagagggg tggggcgggg
    10861 cggtgttccg acggctggac ggcgcggccc ggcgaacggg tggtggcgtc atctcccgtg
    10921 agcgcaacca gacttcgcag gcgatggtcg ggtgcagcag ataactctcc ttctctgcgg
    10981 agagagcacg acggcaccat tcacgcagca cccgctcgtc gaccaggccg agccgggcga
    11041 gccgggagtc ctcgcacagg gccagcagtg cacggcgatg ctcgcgcagc cccgcttcct
    11101 cctcgagcgt ggcgttcgcc ttggtgtcgc ggctgcggct ggcttccggg acgatgccgc
    11161 gcatggcctc gacgatgagc ggcttgtagc accacggggt gatccgctct tgcggccgga
    11221 cggcgagggc cgcctcgatg acgcgggtgt cgtagtaggg ggcgctgacg gcgattccca
    11281 gcggagcggc catctgcccg atgtgccgag ccacttggga gatgccgtcc atcgcgacca
    11341 gctcgcggtg ttcgccgtgt cccctgcccc ggggtcggac ctcggacctc gccgcacgga
    11401 gtagttcgcg cgctgcggtg agggcatcgg gtgtggccca gggcggcatc cggggcggaa
    11461 tcgcccagcc tagcaacggc tcgttgtcgg gcaccgccgg ttcggtcaga tcgcgggcca
    11521 cctggtcgag ccacgcccgg taggggctcc ggtccagaag ctggcgcagc actctccgcc
    11581 gggaccagcg gtacttggcg gcgtatcccc gcacggcctg cacggcgatg agggggtggg
    11641 tgagcagcag cgtatgcaga cgggcgggcg tgccggccag gagctcgtcg ccgcccaggc
    11701 cgatgaggtg gaggccggac ccgcgggcgg ccgccagttc cacgatgccc atccggcggt
    11761 tacggtcgac ggtgaggatg ctgggtgtgt ccaggacgtc ctcaagggcg tcgatcccga
    11821 gaaacgtcat ggccactttc tgggcgggta cgacgtgatg ttcgatgccg ttcagcgctt
    11881 ggacggtccg ctcggcccag tacacgtcgt caccggcctc gtcatggagg gcggcggtgt
    11941 aggcgacgac cttggcgccc ccgcgtgccg cggtgcagca caatgctgtt gagtcgagcc
    12001 ctcccaggtc cgacgtcacc aggtcgcgcc cgcgggtgcg cacctcgacc gcttcggtga
    12061 gggcttccct cagacgcgcg gcgccgatgg cgagcgggac gacggggtca ggcggtgacc
    12121 accaccgcat ggtgcaggtt cgcccgtcgg ggtggagcgt cagacagtgc ccgccgggca
    12181 cggcctgtaa accgcgccac agcggatccc ccgcgctggg atacggcgcg ccgagggtga
    12241 gcagttcgag ggcgattcgc ctctcgtcca gttcggcacc caccagttcg gcgagtacat
    12301 cagcccggtc agacgccacg ctcaccggtc cgtggccggg cgtgccggtc cgggcatgaa
    12361 acacacggcg cagatccacg gcaccggccc gcatccgtac acggccgccg ccgctgacaa
    12421 tcaggtggaa gctgccgggc cagtcggccg cgcggtccac cgctgtcagc gaggcggcgc
    12481 cgtcggccgc ggcggcggcc cgctcggcgt cccgcgccgt gacggcgtgt tcgccgatca
    12541 ccgcgacgcg cgtcccgccg tgctccgcca tcacgacggt ctccggtgcc cagcggccca
    12601 ccagccatgg gcgccctgac gcatgcggca ggctccggtc cgagtagcag agcgccttgg
    12661 cagcgagggc cccggccgcg tcggtgtcgg gcaggacgac gaaccaggcg gatacggcct
    12721 ggagtgacaa ggactgatcc atgggccacg gtctccggtc ggcgatgctc ggaacagagg
    12781 gcgggtggcg gccggctgcc gccacccgat ggccggaccg gcttagcgac cggccgtacg
    12841 cgcgatgccc ggaccgctcc gcggtcgcga gtggcctctg tcagaggagc tgcttgccgc
    12901 cgaggacgtc cttcgggccc gtgttcttga tgccggtgac cttgcggaag ctgccggcct
    12961 tggtgagggt ggggcgctcg taggtcatgg tctttctcct tttcacgcag ggacggtgtg
    13021 cacaaaaggc gcctgtgctt cggatttcag cgactgccat cacggaagtc gaaagcggga
    13081 aatccgaagg acaacaataa gtgcgactag cgtgatatcg caatagcatt ccattgacat
    13141 tgagtggcac ttagggggcg cgcatttcaa gtgcgctacg ggtggacaac cctttgcgcc
    13201 cccgcgacgg cagggcgagc ggccgcgaat gcacacgtgc cggcatcatg agtccgtcac
    13261 ctcggacgac gccacaatca aatcgcgtga tgacccggca agccctacca tccagtcgcc
    13321 ttctgcattt ctcctggtca acggcctgac ggtggggact acaacaggcg ggtggcatcc
    13381 gtgaggcggg ccatgctgta cgtcctgtcg tgtcagccag gctgcggcca gcgctgccgt
    13441 gcgcgccacg attcaggcca tttcaaggtc tcagcgtcgc agtacgttga cccgctcgtt
    13501 tcgtgccgtc ctcgcaggct cgcctggcac cgcgaagagc gccgtcactg ggtcctcgcc
    13561 cgccgcagcg tcagccgacc cgaggagatc tcccactacg tcgcctactg tccggccgac
    13621 accacgctgg acgaactcat acgcatcgca ggcagccgct cggctgtcga ggaatggttc
    13681 cagaccggca agcaggagtg cggcctggac gactaccggg tccgccgcta tcccggctgg
    13741 cgccgccaca ttaccttggc gatgcccgcc cacgcccgcc tcaccggccg ccgtcccacc
    13801 ccccaacggc cacatcctgc actggtcgac atggcgccgt agacgccaac accaagcccg
    13861 catcagtcac tgcaaacgac gcggacacag cccctgaaaa ccgcccagca atcagtgcaa
    13921 acaccgctgc agtatcagag gtcatctcat tggctcggca ggctgcgagc gtggtgggga
    13981 tccgagcgtg gtggggatca ttgagcgact ggtgcgggat gaggtgtggg agttgttcca
    14041 gcgtggtgcc ggcggcgtcg ccgcggcctc gaggagtcgg tcggcgcagg cacagtgacc
    14101 gggcggggcc acggcccggc ctgaactcct cccaccgcct ggtgtgggcg gacggcggtt
    14161 atgccggaag cccagtcgac tgggcccgcg agaagctccg cctctcgcgg gagatcgtca
    14221 gacgcaccga cgacacgacg gggtcgtggt ggtgccgcgc aggtgggtag tggagttgca
    14281 gggcgagccg aaaatttcct ccgcccatag aggcacttgg ccagtgcgaa ggccgtggga
    14341 agtgagttcc tgcaaaacgg cgtccgacgg aaggcgtcct cagtggcgtc acacttccgg
    14401 gacgacttct tcgactgcct gcccatgcgt gggacacgca cctctctctt aaccgggagc
    14461 cggtgggcga actacctgag cacacgggtc cgaactcctg gtcaagcctc gccccgcccc
    14521 gagtcggctt gtagtgcgta ggcaccagga caggtgagtg gctggtccgg gtgcaccagg
    14581 ccaagacggg tgcgggggac gatgcccgtc agggcgccgg agggaagtgt gggaggcgcg
    14641 cgggatctcg cgcattcctc ttgtccagtg gtgtctggag tgattcgcag gtggcggctt
    14701 ttctttaccg gatcgggcgg tgggccttcc ggcggcgtcg gctcgtgggt ggtctgtggc
    14761 tggggggtcc tggcggtgct ggtcgtcgcc gctgccgccg tggcgccggc gggggcggaa
    14821 gagggcctct tcatgcccgg cgccgagtct cagaaggcgt tcgatttgct ggacgagcga
    14881 cagtgaaaag ggcgtccctg tccgaagccg tggtctcccc ggcccgcatc gggtggctgc
    14941 cgatcggtgt cctcggcatc ttggcactcg ccctcggcac cctgcagtca gtggtggagc
    15001 ctgcgctccc gctgctgcaa cgtgagctgg gggtcagtcc ttccgaaggg gccttgatcg
    15061 gcaacgcatt actcatcacc ggcgcggtca tcacacccgt cgcaggaaaa ctcggcgacc
    15121 gctacggcgg aaagcgggtg ttggtccggc tgatgggtgt ggtctcggtg ggtggtctga
    15181 tggccagcct cgcgccgaac ctgccggtgt tgttggtcgg tcaggtattg cagggcgtca
    15241 tggtgggtgc gctgcccctc tcattcatcc tggtgcgcaa acacctcacg gcaggagagt
    15301 cacaggcggc gatcgggctg gtcgtcgcgc tgttcacggg cggcggcatg gtggggacgt
    15361 tgtgtgccgg gccgatcgcg gaaggactgt cctggcagtg gatgttcgcg ctaccgacga
    15421 tcgcgatcat cgccaccacg ttgggcgtga ctcggctgat gccgcatgat ccgccgatcc
    15481 aatcggacga cgggatcgac tggcctggca cggttctgct gagtggcacg ttgctcgcgt
    15541 tcatgctcgg gctcgtgacg gtgacgaggg acggcggcgt gccgtcactt gcggtcggtg
    15601 ccatcgcggt ggtcgtggtc gccctcgcga gcgggtgggt cgtcgtcgag cgccgggcag
    15661 cctcgccgat ggtcgatcta cgcatgctgg caaagccggc tatgtggaac gcatgcgtgc
    15721 tcaccttcgt catgaccgcc agttccggga tggtgctttt ctcctcccgc agttgttcgc
    15781 ggtatcggcc gaggggtacg gattcggagc cagcaccacc gacatcggac tgttcctgct
    15841 gcccggcgcc atcgccgggg cggtaagtga ttcggtcggc gggatcgcgg cgcggcgttt
    15901 cggtccgcgt gccgtggtca tcgtgggcac cgtcgtcacg gccgccacga tgatcgccct
    15961 ggcgtcgctg cacaccgcgg aatggcagct cgtcctcgcg aaggtgctga ccgcgttcgc
    16021 cgcgggcgtc ggtaccacgg cgttgcttgc cggcacggcc accgccatcg agaccaagga
    16081 catcggcatc gccaccggcc tgctcgtggt gactcgcgtg atcggcgtcg ccctgggcgc
    16141 ccagctcgcc ggcgcgatcc tcgacgccgg agccgagccg atgacgggcc ggccggccga
    16201 atcggctttc gtcacaggtt tcgccgtcgc cggcctcgtc gccgcgctgt cactgctcgt
    16261 tgtccgcatc acgaagaaag gagtccaggc atgacgtcta ccgggctgtc gatggacgtg
    16321 agtactaccg cgaagcgcac agttctgatc tccggggcga gtatctccgg acccgcgctg
    16381 gcgtactggc tgcaccggtc cggattcgcg gtcaccgtgg tggagaaggc aggcgcactg
    16441 cgcgacggtg gttacccgat cgatgtccgc ggtaccgcga tagaggtggt ccggcggatg
    16501 ggaattctgc cgcacctgca ggacgcgcac atcgactcgc gtcgcttcac tttcctcaac
    16561 gccgatggca gtgaggtggc ttcgctcacc ccgcgtgccg ttgccggcgg tgtcgaggga
    16621 caggacctcg aggtgcgtcg gggggatctg gccgcgaacc tctacgcgat agttcgcgac
    16681 gacgtggaat tcctgttcgg cgactccatc gacaccctcg accagtccga acgaggggtc
    16741 gaggttcgtc tgcacagtgg gcaacggcgc accttcgacc tggtggtcgg cgccgacggt
    16801 atgcactcac atacccggga gtccctgttc ggccccgagg aacagttcca ccgctacctc
    16861 ggctactgct tcgccatatt caccatgccg aacaccttcg ggctcgcccg cgagctcgtg
    16921 ttgtggaaca cgccggggaa agccgcggcc ctctacgccg tcggggacaa cgacgagttg
    16981 cacgccttcc tgaacttcca ccaaccagaa ccgccggtcg atgccctccg ggaccccgac
    17041 gcccagcggg acctggtcgc cacgatcttc gcaggagcgg gatgggaagt ccctggcctg
    17101 atccaggcca tgcgcgacgc ggatgacctg ttcttcgaca cggccggtca gatccgtatg
    17161 ccccactggt ccagcggccg cgccgcgctc gtcggcgacg ccgcgtacgc gccctcgttc
    17221 ctcaccggac aaggcacaag ccttgcgttg gtcggcgcct acatgctcgc caacgccctg
    17281 gccacacacc gcgattacac tgcggccttc gccgcctacg agcgcgacat gcgcgagttc
    17341 gtagccatga accaggcact ggtcgacaac ggtgcggcca cgctcttccc caccacagtg
    17401 cgggccctgg agcaacgcaa caccattttg cgtgacctcg tcaccatgcc ctccgcgagc
    17461 gcacgaccgg cccactcagc cctgacgctg cccgagttcg cggccgatgc cgtgacctga
    17521 ttgtccagcc ggacttctcc atttccgctg ttcgaaggct tgggtggggg gagggcaggg
    17581 ggacggcagg ccggatgtgc gactacgtgc gcggcctgct cggctccatg ggccccatga
    17641 acagctggta actcgccgaa ttcgcggggc actccccctg ggagtgacta caacgcctgc
    17701 tgtcccaagc cgcggggacg tcgaccgccg ccgcggcgac ctgttgccca ccccgaacag
    17761 caggcccgct ccccgatcga gatgccgggt agcggtgatg acgggagtgg ccagcggcgt
    17821 ccacaatgtc gcggccaggg gtgttcagac cgcggaccgg cacgctctgc cggtttcgga
    17881 ctacgagagg cggtccgcgc cgcctgcggg gccggcttgg gccaggcccg tccggtaggc
    17941 gatgacgacg agttgcgccc ggtcgcgggc ctccagcttc gtcatggcgc gctgtacgtg
    18001 ggcgcgaacg gtgaaggggc tgaggaacat ccgctcggcg atctcctggt tggacaagcc
    18061 ggtcgcaacc gcagccacca tctcgcgttc tcgcggagtg agcgccgcga gctgttcgga
    18121 gtggtgcggc gaaactacct ccggtgtggc caggaaacgg gccaccaagg agcgggtggc
    18181 ggcgggagac agaagggtgt cgccgtcggc gatcgtacgc acggcgtcca acaggtcctc
    18241 ggccccgatg cctttgccga tgaagccgcc ggccccggcg cgcagcgcct gtgcgacgta
    18301 ctcgtctgtc tcgtacgtgg tgagaatgag gatgcggctg gcccgcagtt ccgggtccgc
    18361 gcagatctcc gacgtggcgg tgagaccgtc cacctcgggc atacggatgt ccatgaccac
    18421 cacgtccggg cgcagctccc gggtgagtct caccgcctcc ctgccgtcag cggcctcgcc
    18481 gaccacggtg atgtcgtcgg cgctgtcgag aagcatccgg aaggcaccgc gcagcagggc
    18541 ctgatcgtcg gcgagcagca cccggagcgt cacggcgcat ccctcgtatc gccgtcgccc
    18601 gtccgtccgt tgcctgaccc tccgtcgccc attcgcccct cgatggttgt tgctccgtca
    18661 gttctccgcg tcgtgccctt ggcgggcggg aggggcagct gggtggagac gaggaagccg
    18721 ccctccgggc gcctgcccgc ggagaggtgt cccccgaccg cggtggcacg ttcacgcatt
    18781 ccgatcagac cgtaaccggg cggacggtcc gccgccgtgg acgcacccgg tcccgtggat
    18841 gcggtcggcg ccgtgccgga gccctggccg tcatcggcga cggtgatggt cacgcgatcg
    18901 cggttccaga cgaggtgtac ccgggcgcta ccggtgccgg cgtgtttggt cacgttggtc
    18961 agggcctctt ggacgatgcg gtaggcggtg aggtccactc ccggcggcag cggcctggcc
    19021 gtgccctcct gttggaccga cacctccaga cccgcgcggc ggaaggactc gaggagcgtg
    19081 gaaagccggg acagcccggg cgccggttcg gcgggcgtgg ccgcgtcccc ggactgacgc
    19141 agcagaccga ccgtggcccg caggtcgtcg agcgcgtccg cggtggtttc gacgagctcc
    19201 ttgaggctca tgcgggtctg ctccgggcgg gtgtcgaaga ggtgggcggc gaccgtggcc
    19261 tgcgcgttgg ccagggtgat ctgatgggcc acgaggtcgt gcagttcccg ggcgatgcgc
    19321 acccgttcct cggccactcg ccggcgcgcc tcgctgtccc ggctctgctc ggcccgccgg
    19381 gcccgctcct ccacggccgc caggtaggcc cgtcggttct gcaccgagtg accgagtacg
    19441 ccggccacca gaggaaacac ggccaccact gccatccggc tcgcgtcttt ccacgagaag
    19501 tccccgaaca aggggatgga ggcaaccagc accgtggagg tgagcaacac cgcgctcgcc
    19561 gcgcgccgtt cggtgcgcgc ggcgagcgcg taggagtagg cggtgatcac tacgggggcc
    19621 acgatgagtg gggtcagcag gaggcccagg ggcggcacca gcacgccgac cgcggtcgtg
    19681 gccgtcaggg cggccagggg tgcccggtgc cgcaccggca gtacggcaca ggacaccacg
    19741 gcgacgacgt aggcggcggc aggcggcgct gacagcgtgt cgtcgacctg tatcacacca
    19801 ccgagcagac agaacgcgaa cgccgtcgcc gtgatcgctg cctcccgcca ccacgcaccg
    19861 cgtggccgtg gcccgccgcc acccggtttc gtcatggccg gctcagtccc ggcctacggg
    19921 gagccgccgc accgccgcgt tcggcccggt cgcggagacc gggacgtgcc ggctcagtgc
    19981 ctcaccttcg atatccacat tcggcagcac acggttcagg atacgaggca gccaccaggc
    20041 ccggtggccg agcagtgcca ggaccgcggg tgcgatcgcc atccggacca cgaaggcgtc
    20101 gaaggcgacg gcggcggcca ggccgacacc catcgtctgg atggtcggac tgctcatccc
    20161 gatgaatccg gcgaacacgc tgatcatgat gatcgccgcc gcggccacca cacgtccgct
    20221 gtgccggaaa ccgttgacga tcgcctcgcc ggggcacgcg ccatgggcgt aggcctcccg
    20281 catccgggtg aggaggaaga cctcgtaatc catggcgagg ccgaacacga tgccgatgat
    20341 gagaatcggc atcagcgaca tgaccggtcc ggtctgctcg atgccgacca ggtccgccgc
    20401 ccagccccac tggaagacgg cgacgaggac gccgaaggcg gcccccaccg acagcaggaa
    20461 gccgagcgcg gccttgaccg ggaccaggac cgagcggaag accaccgtca gcaggagcac
    20521 cgccaggccg atgaccacgg tcaggtaggg aatgagggcg tctgacatgg cttcggagat
    20581 gtcgatgttc atcgcggtgg tgccggtcac gaggatggcg gcgcccgtgt cggcctcgac
    20641 gcccaagacc gcgccccgga tcgcgtgcac caggtccttg gtctcgccgc tgttcggcgc
    20701 ggtctgcggg acggcggtga gaaccgccgt gtccttgctc cggctgagca ccggctcacc
    20761 gaccgacgcg accccgtcca ctccccgtac ggtcttgacg accagctccg aggtggcccg
    20821 ggggtccgcg gactccgacg tgtccacgac cacggtcaac gggccgttga agccggggcc
    20881 gaagccctgt gacagcaggt cgtaggcacg gcgctgggtg gtctccaccg acttggactc
    20941 gtctccgggc agcccgagtt cgaggctcag cgccggtagc gcgacggccc cgagaccgag
    21001 tccggcgatc aacagcacgg gcaccggcct gcgcagcacg aaccgcgccc agcgggtgcc
    21061 gagcccaggc cggccgaccg cggtgggcac ccggtgcggg cgctcgctcc ccggccgggt
    21121 ggtcttgcgg acggcacggg acagtacccg ccgaccgaag aagccgaaca gcgcggggac
    21181 cagggtgagt gcgacgagta cggcaagggc cacggcgccc gcgccgccca tgcccatctt
    21241 ggtgagttcg ggtattccga cgacccccag cccggccagg gcgatgaaga cggtcgcacc
    21301 ggcgaagacg acggcggatc cggctgtgcc caccgcccgg ccggcggcct cctccggctc
    21361 gctgccccgg gcgcgctcgt cgcggaagcg ggaggtgacg aagagtgcgt agtcgatgcc
    21421 gaccgcaagg cccaacatca gtgccaggat ggcgacggtg gacgtcaggc ccagtggaac
    21481 ggccagcgcg gagaccaggc cgaaggcgat ggccacgccc acgagggcgg tcagcagcga
    21541 cagtccggcc gcgaccagtg acccgagggc gaggaccagt accaccgccg ccaccgccac
    21601 gccgatgatc tccgtcgtac cgcccggttc ctcctccgcg tccagggccg agccgccgat
    21661 ctccacggtc agccccgcgt cccgggcccg gctcgcggcg tcctcgaggg cgctcttcgt
    21721 cggctgggtc aggtcgacgg cgtccgcggt gtaggtgatc gtggagtagg cgatggtgcc
    21781 gtcctcgctg acagcgccgg tctcataggg gttggtggtc gacgcgacct gatcgccccc
    21841 gtccagcgag ccgagcgtgt cctcgacggc cgccttgttc tccctggccg tcacccgctg
    21901 cccgtccgga gcctggaaca ccaaacgggc ctcggcgccc tgggagttgc tctgggggaa
    21961 gcgctcgtcc agcaggtcga acgccttctg cgactcggtg ccgggcatgg agaggtcctc
    22021 ctcctccccg gtcggcgcca tggcggcggc gccaatggcc agcaacagga cacccagcca
    22081 cagaccaccc acgagccggc gccgccggaa ggcccaccgt ccgatccggt aaagaaaggt
    22141 cgccacctgt cgatcactcc agacgccgct aggcaagggg aatgtgcgag attcacgctc
    22201 ctccaaccct ccgctccagc gccccgccgg gcatcgcccc ccgccaccgt cttcccctgg
    22261 tgcgcccgca ccagccgctc acgtgcccta gtgcctgcgc actacaggcc gacttgggcc
    22321 gccgggcggg acttgacctg gagttcagtg gcctgggcta tagccggact gtcacggccg
    22381 tgaccgagtg gggcgcgccg acggtgtccc accgggactc gggctgcgac acggacaccg
    22441 catgagccat gcgagcacaa cccagcctgc tggtccgaga atcgcagatc gggtggtcac
    22501 ggtggtcacg gtggccacgc acagcctgga gcaggtttga gcggcatcaa gcacgtaaag
    22561 gtctcgctgg actccgcgac gaacgtcgca gcgccgggcg atgctgctcg accgggaaag
    22621 ccgaggacat ccgtgtcgga acatgagcca gccgtccgct acaccgaagt cgcgaaccag
    22681 gatgtgcgca gtctgcggac gcgttactgc cggttgcaca ccgacggagg cgcaccggtc
    22741 gc
//
