LOCUS       NZ_LT907981            12981 bp    DNA     circular CON 12-FEB-2024
DEFINITION  Streptomyces sp. 2323.1 chromosome I.
ACCESSION   NZ_LT907981
VERSION     NZ_LT907981.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. 2323.1
  ORGANISM  Streptomyces sp. 2323.1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 03:31:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,058
            CDSs (total)                      :: 6,971
            Genes (coding)                    :: 6,808
            CDSs (with protein)               :: 6,808
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 163
            CDSs (without protein)            :: 163
            Pseudo Genes (ambiguous residues) :: 0 of 163
            Pseudo Genes (frameshifted)       :: 64 of 163
            Pseudo Genes (incomplete)         :: 123 of 163
            Pseudo Genes (internal stop)      :: 17 of 163
            Pseudo Genes (multiple problems)  :: 37 of 163
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7435879
            Orig. end                         :: 7448860
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT907981.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..12981
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="32"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12981
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12981
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7981](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7981
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     gene            complement(383..1156)
                     /locus_tag="CPH93_RS32175"
                     /old_locus_tag="SAMN06272775_6538"
     CDS             complement(383..1156)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (9-212). E-value: 2.2e-40. Score:
                     130.5. Matches aSDomain:
                     nrpspksdomains_CPH93_RS32175_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606664.1"
                     /locus_tag="CPH93_RS32175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_6538"
                     /product="enoyl-CoA hydratase family protein"
                     /protein_id="WP_096214843.1"
                     /transl_table=11
                     /translation="MGVSTSRPDHGIALVTVDFPPVNALPVQGWYDLADAVRAAGHDPD
                     LRCVVLAAEGRGFNAGVDIKELQRDTAAGGHDALIGFNRGCAEAFSAVYTCEVPVVAAV
                     HGFCLGGGIGLAGNADAIVASEDATFGLPELDRGALGAATHLARLVPQHLMRALYYTSR
                     TATAAELQAHGSVWKVVPRAGLRRAALDLAREIARKDGALLRLAKAAINGIDPVDVHRS
                     YRFEQGFTFEANLSGVADRVRDTFGAPAGAPTTEG"
     aSDomain        complement(521..1129)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPH93_RS32175_ECH.1"
                     /evalue="2.20E-40"
                     /label="CPH93_RS32175_ECH.1"
                     /locus_tag="CPH93_RS32175"
                     /protein_end="212"
                     /protein_start="9"
                     /score="130.5"
                     /tool="antismash"
                     /translation="HGIALVTVDFPPVNALPVQGWYDLADAVRAAGHDPDLRCVVLAAE
                     GRGFNAGVDIKELQRDTAAGGHDALIGFNRGCAEAFSAVYTCEVPVVAAVHGFCLGGGI
                     GLAGNADAIVASEDATFGLPELDRGALGAATHLARLVPQHLMRALYYTSRTATAAELQA
                     HGSVWKVVPRAGLRRAALDLAREIARKDGALLRLAKAAIN"
     misc_feature    complement(1176..1189)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.89"
                     /tool="antismash"
     misc_feature    1180..1193
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.96"
                     /tool="antismash"
     misc_feature    complement(1192..1208)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.58"
                     /tool="antismash"
     gene            1239..2114
                     /locus_tag="CPH93_RS32180"
                     /old_locus_tag="SAMN06272775_6539"
     CDS             1239..2114
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (11-167). E-value: 5.9e-13.
                     Score: 41.1. Matches aSDomain:
                     nrpspksdomains_CPH93_RS32180_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606665.1"
                     /locus_tag="CPH93_RS32180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_6539"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_096214844.1"
                     /sec_met_domain="adh_short (E-value: 1.4e-32, bitscore:
                     111.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.1e-30, bitscore:
                     104.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLTLDLSGQLAVVTGGTRGVGAGIARAFLRAGAEVVICARRPPA
                     SPVTAAGRSARFHPLDLREPDAVRAFFDRLAATHGRLDCLVNNAGGTPYRLLGQTDADR
                     HARVVALNLLAPLTASLAAYEVMRQQPAGGSVLMIGSVSGTRPSPGTAAYGAAKAGLEN
                     LARSMAVEWAPLVRVNTLVLGMVRTELSALHYGDEAGIAAVGATVPAGRLAEPAEIGDA
                     CVFLASDRAAYVTGASLLVHGGGERPAFLDAATVNRPTVNHSMANHPTAFREVSDETPS
                     IADAEAPKEN"
     aSDomain        1272..1739
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPH93_RS32180_PKS_KR.1"
                     /evalue="5.90E-13"
                     /label="CPH93_RS32180_PKS_KR.1"
                     /locus_tag="CPH93_RS32180"
                     /protein_end="167"
                     /protein_start="11"
                     /score="41.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="AVVTGGTRGVGAGIARAFLRAGAEVVICARRPPASPVTAAGRSAR
                     FHPLDLREPDAVRAFFDRLAATHGRLDCLVNNAGGTPYRLLGQTDADRHARVVALNLLA
                     PLTASLAAYEVMRQQPAGGSVLMIGSVSGTRPSPGTAAYGAAKAGLENLARS"
     CDS_motif       1275..1361
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPH93_RS32180_0001"
                     /evalue="5.40E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="CPH93_RS32180"
                     /protein_end="41"
                     /protein_start="12"
                     /score="12.6"
                     /tool="antismash"
                     /translation="VVTGGTRGVGAGIARAFLRAGAEVVICAR"
     CDS_motif       1647..1736
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPH93_RS32180_0002"
                     /evalue="1.10E-04"
                     /label="PKSI-KR_m4"
                     /locus_tag="CPH93_RS32180"
                     /protein_end="166"
                     /protein_start="136"
                     /score="14.8"
                     /tool="antismash"
                     /translation="LMIGSVSGTRPSPGTAAYGAAKAGLENLAR"
     gene            2116..3027
                     /locus_tag="CPH93_RS32185"
                     /old_locus_tag="SAMN06272775_6540"
     CDS             2116..3027
                     /NRPS_PKS="Domain: PKS_KR (10-176). E-value: 2.6e-16.
                     Score: 52.0. Matches aSDomain:
                     nrpspksdomains_CPH93_RS32185_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606666.1"
                     /locus_tag="CPH93_RS32185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_6540"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_096214845.1"
                     /sec_met_domain="adh_short (E-value: 2.4e-31, bitscore:
                     107.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGICAGRVAAVTGAGRGLGRAHALALAAEGAEVVVNDLGVAADG
                     AGASAGPAQQVADEIRAHGGQAVAHRGDITTTEGAASLVATALDTFGRLDTLVNNAGFL
                     RDRMLVNLDEDDWDAVIRVHLKGHFLPLRHAAAHWRAEAKSGRTPDARVINTSSGAGLL
                     GSVGQGNYSAAKAGIIGLTLVAAAEMARYGVQINAIAPAARTRMTERTFAATMAAPADG
                     EFDAMAPENVSPLVVWLSSADSAGVTGRVFEAEAGRITVMEGWRPGPTADKGSRWSPAE
                     AGAAARRLLAVAEEPGAVYGAR"
     aSDomain        2146..2643
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPH93_RS32185_PKS_KR.1"
                     /evalue="2.60E-16"
                     /label="CPH93_RS32185_PKS_KR.1"
                     /locus_tag="CPH93_RS32185"
                     /protein_end="176"
                     /protein_start="10"
                     /score="52.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="AVTGAGRGLGRAHALALAAEGAEVVVNDLGVAADGAGASAGPAQQ
                     VADEIRAHGGQAVAHRGDITTTEGAASLVATALDTFGRLDTLVNNAGFLRDRMLVNLDE
                     DDWDAVIRVHLKGHFLPLRHAAAHWRAEAKSGRTPDARVINTSSGAGLLGSVGQGNYSA
                     AKA"
     CDS_motif       2581..2637
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPH93_RS32185_0001"
                     /evalue="1.00E-06"
                     /label="PKSI-KR_m4"
                     /locus_tag="CPH93_RS32185"
                     /protein_end="174"
                     /protein_start="155"
                     /score="21.3"
                     /tool="antismash"
                     /translation="TSSGAGLLGSVGQGNYSAA"
     gene            complement(3092..3883)
                     /locus_tag="CPH93_RS32190"
                     /old_locus_tag="SAMN06272775_6541"
     CDS             complement(3092..3883)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606667.1"
                     /locus_tag="CPH93_RS32190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_6541"
                     /product="uracil-DNA glycosylase"
                     /protein_id="WP_096214846.1"
                     /transl_table=11
                     /translation="MDETGAAQTPPGSDEEAFPAYRAARCDGLAELDAQLIGCRACPRL
                     VEWRERTGAHPRAAFRDWEYWARPVPGFGPPDAALAVVGLAPAAHGGNRTGRMFTGDAS
                     GDFLFRALHAVGLASQPTATHRGDGLELYGVRVTAPVHCAPPENKPTPTERRTCRPWLS
                     AELELLSPHLRTVVALGAFSWQALLPVLGEAGWPLPRPRPAFGHGVQLTLPAAGPRREL
                     QVLGSYHPSQRNTFTGRLTFDMLVELLARAAGLAGLGRPGG"
     gene            complement(3945..4649)
                     /locus_tag="CPH93_RS32195"
                     /old_locus_tag="SAMN06272775_6542"
     CDS             complement(3945..4649)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606668.1"
                     /locus_tag="CPH93_RS32195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_6542"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_096214847.1"
                     /transl_table=11
                     /translation="MTSPSPGRTLSETERTRHRRLREQGSLDRAALDAVLAAGFLCHLG
                     VLVDGSPMVVPTVYGADGSTLYFHGSVASRSLIASPGANVCVTVTHVDGLVLARSVFEH
                     GVNYRSAMVFGTPRQVTDPEEKLAGLRCLTEQAAPGQWDYARRPSRKELAATALLALSL
                     DEASVKIRTGPPDDGDGADAELGLWAGVLPLHSSWGPLEPAPALPTDLAPPAHLAERAA
                     SPAGRRGPDAAV"
     misc_feature    4756..4772
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.45"
                     /tool="antismash"
     misc_feature    complement(4772..4786)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.68"
                     /tool="antismash"
     misc_feature    4979..4988
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.04"
                     /tool="antismash"
     gene            5001..6173
                     /locus_tag="CPH93_RS32200"
                     /old_locus_tag="SAMN06272775_6543"
     CDS             5001..6173
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309277.1"
                     /locus_tag="CPH93_RS32200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_6543"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_231977030.1"
                     /sec_met_domain="DAO (E-value: 1.3e-67, bitscore: 227.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTRHRHSLDAADVVIVGAGVVGAACAYYAGRAGLSVAVVDRGPV
                     AGGTTGAGEGNLLVSDKEPGPELALALLSTRLWRELAAALPPEIEYETKGGLVVAADES
                     GMTSLRAFRAAQEKAGVESTDVPGDRLRDVEPHLAPGLAGGVLYPQDAQVQPALAAAHL
                     LRASGARLHLGAEVTAILRGPGGAVRGVRTPRGDLLAPAVVNATGTWAGRLASLAGVTV
                     PVLPRRGYVLVTEPLPRVVRRKVYAADYVADVASGSAALQTSAVVEGTPAGPVLIGASR
                     ERVGFDRTLSADVLRRLAAQAAALFPVLAGVRVIRTYQGFRPYLPDHLPAIGPDPRAPG
                     LLHACGHEGAGIGLAPATGRLIAAALTDAPGPLDARPFRPERFTEGTEPE"
     gene            6286..6612
                     /locus_tag="CPH93_RS32205"
                     /old_locus_tag="SAMN06272775_6544"
     CDS             6286..6612
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309276.1"
                     /locus_tag="CPH93_RS32205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_6544"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_093481765.1"
                     /sec_met_domain="Fer2_4 (E-value: 3.3e-25, bitscore: 86.6,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSRRRTPAELVRAVPGPAFEITLDGRSLSALPGQSIAAALWAA
                     GVLSWRTTRQSGRARGAFCGIGSCFDCLATVNGVPNQRACLVPARPGDAVTTQEGHGRA
                     ELAV"
     gene            6593..7981
                     /locus_tag="CPH93_RS32210"
                     /old_locus_tag="SAMN06272775_6545"
     CDS             6593..7981
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606671.1"
                     /locus_tag="CPH93_RS32210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_6545"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_096214849.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.1e-26, bitscore:
                     91.5, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 1.2e-11, bitscore:
                     43.5, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNSPSDTHDLAVIGAGPAGLAAAVTAADLGLTVALVDAAARPGG
                     QFYRQSAPGLGAARPQALHHSWGAFARRAARLEVHRAAGRVHHFTEHHVWSVTREAEHW
                     AVRAMTGPDGAQGRAEVAARKVLLATGAYERQLPFPGWTLPGVVGAGGAQAMLKAGLVV
                     PGQRIVVAGSGPLLLAVAGSLAAAGARVPVVAEAGGYAGYARAPRTLAANPRKLVEGAS
                     HAATLRRYGVRLRTHSAITAVHGTDRVEAVTLTRLDRDWRPVAGTGLRIPCDALAVGHG
                     LVPQLDLATALGCATRRCPDGTAALVLDGRQRTTVDGVWAAGEAGGVGGAELALVEGEL
                     AAYDIARRTAGDALRRRRDRLRRFAGAMSAAHAPRPGWSDWLGADTEVCRCEEVTAGRI
                     REAVGGLGAGDTRTVKLLTRAGMGWCQGRVCGPAVAHLAGETETGAGRRLLACPVTLGE
                     LARE"
     misc_feature    complement(8016..8030)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.31"
                     /tool="antismash"
     misc_feature    complement(8020..8035)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    8025..8035
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            8058..8954
                     /locus_tag="CPH93_RS32215"
                     /old_locus_tag="SAMN06272775_6546"
     CDS             8058..8954
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606672.1"
                     /locus_tag="CPH93_RS32215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_6546"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_096214850.1"
                     /transl_table=11
                     /translation="MVIRTRPWHGIMVATTLPFRDDLSVDHDAYAAQVARLLAADCDGV
                     VPNGSLGEYQTLTDDERAQVVRTAVAAAGAGDRVMPGVSAYDSATACRWAEQAAEAGAG
                     SVLLLPPNAFRADPAAVRAHFAEVAAVGLPVVAYNNPYDTKVDLTPRLLAELHADGSIV
                     AVKEFSGDVRRAYEIAEVAPELDLLIGADDVLLELALAGAVGWIAGYPNALPEACGSLY
                     RAAVAGDLDTALPLYRALHPLLRWDSKPEFVQAIKLSMDLAGHRGGPTRPPRFPLPAGQ
                     SAQLRAATEKLLADGHH"
     gene            8965..9966
                     /locus_tag="CPH93_RS32220"
                     /old_locus_tag="SAMN06272775_6547"
     CDS             8965..9966
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891275.1"
                     /locus_tag="CPH93_RS32220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_6547"
                     /product="proline racemase family protein"
                     /protein_id="WP_096214851.1"
                     /transl_table=11
                     /translation="MRTRHVFHAVDSHTEGMPTRVITGGIGTLPGATMAERRLYMAEHR
                     DDIRTLLMYEPRGHAAMSGAILQAPTRPDADWGVLFIEVSGYLPMCGHGTIGVATVLVE
                     TGMVAVCEPVTTVRLDTPAGLVTAEVQVTDGAATAVTLTNVPAFCAGLDRKVTVPGYGT
                     LSYDLAYGGNFYAILPLDSVGLPFDRDRKNDILSAGLALMDAVNATDRPVHPEDERIGG
                     LKHVYFAAPGSNATRSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGELFLGQDFVNES
                     FIGTEFTGRLVGRTTVGGRPAVVPTVTGRAWVTGTAQYFLDPADPFPAGFLL"
     misc_feature    complement(10013..10026)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.02"
                     /tool="antismash"
     misc_feature    complement(10022..10032)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            10066..10770
                     /locus_tag="CPH93_RS32225"
                     /old_locus_tag="SAMN06272775_6548"
     CDS             10066..10770
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606674.1"
                     /locus_tag="CPH93_RS32225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_6548"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_096214852.1"
                     /transl_table=11
                     /translation="MGELKHRSLITAQERLRDQVAHQLRAALIAGELRPGSVYSAPGLA
                     ADFGVSATPVREAMLDLAREGLVEPVRNKGFRITEVSERDLDQYTEIRALIEVPVIGQV
                     TRTAGREQLEALRPAALEIVAAARAHDLIGYLEADRRFHLALLGLSGNDRLVETVGELR
                     KRSRLYGLTRLDERNQLLPSAEEHVELLDLMLTGDAEAAEACMARHLGHVRSLWAQARA
                     EPPVPELRDRQG"
     gene            complement(10810..12195)
                     /locus_tag="CPH93_RS32230"
                     /old_locus_tag="SAMN06272775_6549"
     CDS             complement(10810..12195)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606675.1"
                     /locus_tag="CPH93_RS32230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_6549"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_096214853.1"
                     /transl_table=11
                     /translation="MTLHHPQLHTGSHDLPVSSALADFMTDGWATPSLPAGTCVPGFAH
                     FAGRRARLAARFPGERLLVPAGELRVRSHDCDHRFRPHSAYAWLTGLTGEDQPGHVLVL
                     EPDGEAVLYLRPRSPRDADGAFYRDRKYGEFWVGRRPDLAEAEQLTGVRCAHLDDLAPR
                     PSDRNAAQDAELATALSELRLVKDAWEVDQLQQAVDHTVTGFEDVVRSLPAALRHPRGE
                     RWIEGVFQLRARAEGNGTGYETIAAAGAHACVLHWIRNDGPLDPDQLLLLDAGVETDSL
                     YTADITRTLPLSGRFSPVQRRVYELVLAAQDAGIAALKPGASFRDFHRACSGVLAEGLA
                     DWGVLRIPAAQALAADSGLHRRYTLCSSGHMLGLDVHDCGRARAEQYLDGVLTEGQVLT
                     VEPGLYLQPDDETLPRELRGIGVRIEDDLVITADGARLMSGGLPRTVDGVEEWMDGLLA
                     GNA"
     misc_feature    12233..12249
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.29"
                     /tool="antismash"
     misc_feature    12237..12247
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
ORIGIN
        1 tccgagccga gaccggcccg gacggggagg aacggcagcc ggtgggcggc ggcggtgagg
       61 ccccacagga acatcgcctc gtcgatctcc cgcagctcga acgcaccacg ctggcgcgcc
      121 gcgcggaagt gcggctccag ggggatcgag tcgagggtca cgaacgccgc gaccagcgtg
      181 cggatccggc ccgcggcggc gagcagcccg acatcgggac cgccgtacga gatcaccgtc
      241 agatcggtga tgtcggagcg cagcagcgcc cgtaccagcg ccatcggctt acggcgtgcc
      301 ccccagccgc cgatgccgag ggtcatcccg ctgcgcagcc gggagaccac gtcctcgggc
      361 gtcatggtct tgtcggtcac ggtcagcctt ccgtcgtcgg tgcgccggcc ggtgcgccga
      421 acgtgtcgcg gacgcggtcg gcgacaccgc tgaggttcgc ctcgaaggtg aagccctgct
      481 cgaagcggta actgcgatgg acgtccacgg ggtcgatgcc gttgatcgcg gccttggcga
      541 gccggagcag agcgccgtcc ttccgggcga tctcccgcgc cagatccagt gcggcgcggc
      601 gcagaccggc gcgcgggacg accttccaca ccgagccgtg cgcctggagt tcggcggcgg
      661 tggcggtgcg cgaggtgtag tagagcgcgc gcatcagatg ctgggggacc agccgggcca
      721 gatgggtggc cgcgccgagc gcaccgcggt ccagctccgg caggccgaag gtggcatcct
      781 cgctggccac gatcgcatcc gcgttcccgg ccagcccgat gccgccgccc agacagaagc
      841 cgtgcaccgc cgcgacgacc ggcacttcgc acgtgtagac cgccgaaaac gcctcggcac
      901 agccgcggtt gaaaccgatc agggcgtcat gaccgccggc ggcggtgtcc cgctgcaact
      961 ccttgatgtc gacaccggcg ttgaagccgc ggccctcggc ggcgaggacg acacagcgca
     1021 ggtccgggtc gtgcccggcg gcccgtacgg catcggcgag gtcgtaccag ccctgtacgg
     1081 gaagggcgtt gaccggcggg aagtcgacgg tgaccagggc gatgccgtgg tccggcctgg
     1141 aggtggagac acccatgagc ggatcagcta cctttccacc aagcgtttgt taggtagcga
     1201 agttagcagc ggaccgcgcg ctgcgggagg ggtgccgggt gagcctgacc ctcgatctgt
     1261 ccggacagct cgccgtggtc accggcggca cccggggcgt cggcgccggc atcgcccgcg
     1321 ccttcctgcg ggccggcgcc gaggtggtga tctgcgcccg ccggccgccg gccagccccg
     1381 tcacggcggc cggccgcagc gcccgtttcc accccctcga tctgcgtgaa cccgacgccg
     1441 tacgggcctt cttcgaccgg ctcgcggcga cgcacggccg gctggactgc ctggtgaaca
     1501 acgccggcgg cacgccgtac cggctgctcg gacagaccga cgccgaccgg cacgcccggg
     1561 tcgtcgcgct caacctcctc gccccgctga ccgcttcgct cgccgcctac gaggtgatgc
     1621 ggcagcagcc ggccggcggt tcggtcctca tgatcggcag cgtcagcggc acccgtccgt
     1681 cgcccggcac cgccgcctac ggcgcggcca aggcgggcct ggagaacctc gcccgctcca
     1741 tggccgtcga atgggctcct ctggtccgcg tcaacaccct cgtcctcggc atggtgcgca
     1801 ccgaactctc cgccctgcac tacggggacg aggcgggcat cgccgccgtc ggcgccaccg
     1861 tcccggccgg ccggctcgcc gaacccgccg agatcggcga cgcctgcgtc ttcctcgcct
     1921 ccgaccgggc cgcgtacgtc accggcgcca gcctgctcgt ccacgggggc ggcgagcgcc
     1981 ccgccttcct ggacgccgcc accgtcaacc gccccacggt caaccactcc atggccaacc
     2041 accccaccgc cttccgtgaa gtgtccgacg agaccccctc gatcgccgat gccgaagccc
     2101 ccaaggagaa ttgacatgac cggaatctgc gccggacggg tcgccgccgt cacgggagcc
     2161 ggccgggggc tcggccgggc ccatgcgctg gccctcgccg ccgagggagc cgaggttgtg
     2221 gtgaacgacc tcggggtggc tgccgacggc gccggcgcct cggccggccc ggcccagcag
     2281 gtcgccgacg agatccgcgc acacggcggc caagccgtcg cccaccgcgg cgacatcacc
     2341 accaccgaag gcgccgcctc cctcgtcgcc accgccctgg acaccttcgg ccggctcgac
     2401 accctcgtga acaacgccgg attcctgcgc gaccggatgc tcgtcaacct cgacgaggac
     2461 gactgggacg ccgtcatccg cgtccacctc aagggccact tcctcccgct gcggcacgcc
     2521 gcggcccact ggcgggccga ggccaagtcc ggccgcaccc ccgacgcccg cgtcatcaat
     2581 acctcgtcgg gcgccgggct gctcggcagc gtcggacagg gcaactactc cgccgccaag
     2641 gccggcatca tcggcctcac cctcgtcgcc gccgccgaaa tggcccgcta cggcgtccag
     2701 atcaacgcca tcgcgccggc cgcccgcacc cggatgaccg agcggacctt cgccgcgacg
     2761 atggcggcgc cggccgacgg ggagttcgac gcgatggccc cggagaacgt ctccccgctg
     2821 gtggtctggc tctcctccgc cgacagcgcc ggggtcaccg gccgggtctt cgaggccgag
     2881 gcgggccgga tcacggtgat ggagggctgg cgccccggcc ccaccgcgga caaggggagc
     2941 cgctggtccc cggccgaagc gggcgcggcc gcccgccggc tgctggccgt cgccgaggag
     3001 ccgggagcgg tgtacggcgc gcggtgaccg ggccggggac ccgaccgggt gcgcaccact
     3061 cgcggcagcc ggtgtcccgg gcccggtgct ttcagccgcc cggacgcccc agccccgcga
     3121 gcccggcggc gcgcgccagc agctcgacga gcatgtcgaa ggtgagccgg ccggtgaacg
     3181 tattgcgctg gctggggtgg tagctcccca gcacctgcag ttcccgccgg gggcccgcgg
     3241 ccggcagggt cagctggacg ccgtgaccga acgccggccg gggacggggg agcggccacc
     3301 ccgcctcgcc gagtacgggc agcagcgcct gccagctgaa ggcgcccagc gccacgaccg
     3361 tccggaggtg ggggctgagg agttccagct ccgccgacaa ccacggccgg caggtgcggc
     3421 gctcggtggg cgtcggcttg ttctccggcg gagcgcagtg gaccggcgcg gtgacccgga
     3481 ccccgtacag ttccaggccg tcgccccggt gcgtcgcggt cggctgggag gcgaggccga
     3541 ccgcatgcag tgccctgaac aggaagtcac cggaggcgtc cccggtgaac atccggccgg
     3601 tgcggttgcc gccgtgcgcg gccggcgcca gcccgacgac ggccagtgcc gcgtcgggcg
     3661 gcccgaaccc cgggacgggg cgcgcccagt actcccagtc ccggaacgcc gcacgcggat
     3721 gcgcgccggt ccgctcccgc cattccacca gccggggaca ggcccggcac ccgatcaact
     3781 gcgcgtcgag ctcggcgagc ccgtcgcacc gcgccgcgcg gtaggccgga aaggcctcct
     3841 cgtcgctgcc cggcggtgtc tgcgccgccc cggtctcgtc cattcctcca cgctaggcgg
     3901 tgtccgcaac gtcccgcccc tgacacggtc gggcggagca ggcatcagac agcggcgtct
     3961 ggaccgcggc ggccggccgg ggacgcggca cgctcggcga gatgcgcggg aggggcgagg
     4021 tccgtgggga gcgcgggggc cggttcgagg gggccccagg aggagtgcag gggaagtaca
     4081 ccggcccaca ggccgagttc ggcgtccgca ccgtccccgt cgtccggcgg acccgtccgg
     4141 atcttcacgg aagcttcgtc gagggagagg gcgagcaggg ccgtggcggc gagttccttg
     4201 cggctcgggc gccgggcgta gtcccactgg cccggcgccg cctgttcggt cagacagcgc
     4261 agaccggcga gcttctcctc cgggtcggtg acctggcggg gagtgccgaa caccatcgcg
     4321 ctgcggtagt tgacgccgtg ctcgaacacc gagcgggcca gcaccagccc gtcgacatgc
     4381 gtcacggtga cacagacatt cgcgccgggc gaggcgatca ggctgcggct ggcgaccgac
     4441 ccgtggaagt acagcgtgct gccgtccgcg ccatagaccg tgggcaccac catcggtgag
     4501 ccgtccacga gcacaccgag gtggcacaga aagccggcgg ccagcacggc atcgagcgcg
     4561 gcccggtcga ggctgccctg ctcacgcagc cggcgatggc gggtgcgctc ggtctccgac
     4621 agcgtccgcc cgggcgaggg ggaggtcatc acggcccttc cgaagggtgc gggggagggg
     4681 gcggggcagg tagccgaccc tttcccagga ttctactgat cccgtggtcg tctcgctaga
     4741 tggagcggga tttcgtcgcc ataaactcat atggcaacga attccgcaca ccgagtcctc
     4801 cggcttcggc ttctgctccg acatgccccc ggcccttggt caggtcgccc ctccgccgcc
     4861 ccccggggcc gtacgaggcg ccaagcatgg gtacgacacg ggatgggcag ccccattcca
     4921 cccgccgccc tgggggagtt cgcggccgag gatcacgaag tacccttttc cgagactgtg
     4981 ttgtgtgaca tattactgac gtgcccacga gacacagaca ctccctggat gcggcggacg
     5041 tcgtgatcgt cggggccggt gtggtcggcg ccgcctgtgc gtactacgcc ggccgcgccg
     5101 gtctctccgt cgccgtggtc gaccgcggac ccgtcgcggg cggcaccacc ggagccggcg
     5161 agggaaacct gctggtctcc gacaaggagc cgggcccgga actcgcgctc gcgctgctct
     5221 ccacccgcct gtggcgcgaa ctggccgccg cactcccgcc ggagatcgag tacgagacga
     5281 agggcggcct ggtcgtcgcc gccgacgagt ccggtatgac gtccctgcgc gcgttccgtg
     5341 cggcgcagga aaaggcgggc gtggagagca cggacgtccc cggcgaccgg ctgcgggacg
     5401 tcgaacccca tctcgcgccc ggcctcgccg gcggcgtcct ctacccgcag gacgcgcagg
     5461 tccagcccgc cctggccgcc gcccacttgc tgcgtgcctc cggagcccga ctgcatctgg
     5521 gggccgaggt cacggccatc ctgcgcgggc ctggcggggc ggtccgcggc gtccgtaccc
     5581 cgcgcggcga cctgcttgcc cccgcggtcg tgaacgccac cggcacctgg gccggccggc
     5641 tggcctcgct cgcgggggtg accgtccccg tcctgccgcg ccggggatat gtgctggtca
     5701 ccgagccact gccgcgtgtc gtacgccgca aggtgtatgc cgcggactat gtcgccgacg
     5761 tggccagcgg ctcggccgcg ctgcagacct ccgccgtcgt cgagggcacc ccggcgggcc
     5821 cggtgctcat cggcgccagc cgggaacgcg tcggcttcga ccgcacgctc tcggccgacg
     5881 tgctgcgccg gctcgccgcc caggcggcgg cgctgttccc cgtcctggcg ggcgtccggg
     5941 tgatccgtac gtaccagggc tttcggccct atctcccgga ccacctcccg gcgatcggcc
     6001 ccgatccgcg tgccccgggt ctgctgcacg cctgtggcca cgagggcgcg ggcatcggcc
     6061 tcgccccggc caccggccgg ctgatcgccg ccgcgctgac ggacgccccc ggcccgctgg
     6121 acgcgcgccc gttccgcccg gagcgcttca ccgaaggaac ggagccggaa tgagcggagt
     6181 cagggtgaac cccgccggga cgaaccgagt ggggaggggc cgcgccgctc cgcacgccgc
     6241 cccgccgcaa tccactccac acccccgcgc cgaacggagc ccggtatgac ccgaagccga
     6301 cgccgcaccc cagccgagct cgtacgggcc gtgccaggac cggcgttcga gatcacgctc
     6361 gacgggcggt cgctgtccgc gctgcccggg cagagcatcg cggccgcact ctgggcggcg
     6421 ggggtgctct cctggcggac cacgcgccag agcggccggg cgcggggcgc cttctgcggg
     6481 atcggttcct gcttcgactg tctcgccacc gtcaacggcg tccccaatca acgggcctgc
     6541 ctggtgccgg cccggccggg ggacgcggtc accacccagg agggacacgg gcgtgccgaa
     6601 ctcgccgtct gacacccatg acctcgccgt catcggcgcg gggccggccg ggctcgcggc
     6661 cgccgtcacc gccgccgacc tcgggctgac cgtggcgctg gtcgatgccg ccgcccggcc
     6721 cggcggacag ttctaccggc agtcggcccc cgggctgggc gcggcccgtc cgcaggccct
     6781 gcaccactcc tggggcgcgt tcgcccggcg tgcagcccgg ctggaggtgc accgggcggc
     6841 cgggcgggtc caccacttca ccgagcacca tgtctggtcg gtcacccggg aggcggagca
     6901 ctgggccgta cgcgcgatga ccgggcccga cggggcgcag gggcgggccg aggtggccgc
     6961 gcggaaggtg ctcctcgcca ccggtgcgta cgagcgtcaa ctgcccttcc ccggctggac
     7021 cttgcccggc gtcgtgggtg ccggcggtgc gcaggccatg ctcaaggcgg ggctggtggt
     7081 gccggggcag cggatcgtgg tcgcgggcag cgggccgctg ctgctcgccg tcgcggggtc
     7141 gctggccgcc gccggagcca gggtgccggt ggttgctgag gcaggcggct acgccggata
     7201 cgcccgcgcg ccgcgcaccc tcgccgccaa cccgcgcaag ctcgtcgaag gggcttcgca
     7261 cgcggccacc ctgcgtcggt acggcgtccg cctccgtacc cacagcgcga tcaccgccgt
     7321 gcacggcacc gaccgggtcg aggccgtcac cctgacccgg ctcgaccggg actggcggcc
     7381 ggtggccggg accgggctgc gcatcccgtg cgatgcgctc gccgtcgggc acggactcgt
     7441 accgcagctg gacctggcga ccgcgctggg ctgtgcgacc cgccgttgtc ccgacggcac
     7501 cgccgcgctg gtcctcgacg gccggcagcg gaccacggtc gacggggtct gggctgccgg
     7561 ggaggccggc ggtgtagggg gtgccgaact cgcccttgtg gaaggggagt tggcggcgta
     7621 cgacatcgcg cggcggacgg cgggggatgc gctgcggcgg cgtcgtgacc ggctgcggcg
     7681 gttcgccggg gcgatgtccg ccgcgcatgc gccgcggccg ggctggtccg actggctcgg
     7741 cgcggacacc gaggtctgcc gctgcgagga ggtcacggcc ggccggatcc gggaagccgt
     7801 cggcggcctc ggggccggcg acacccgcac cgtcaaactg ctcacccggg ccggcatggg
     7861 ctggtgccag gggcgggtat gcggtcccgc cgtggcgcac ctcgcggggg agaccgaaac
     7921 cggggccggc cgcaggctcc tcgcctgccc cgtcacgctg ggcgaactcg cccgagagta
     7981 atgccggttc ggatcggcgg tcttggcaat ccgctaaagg tcagtaaaat gtcacacctc
     8041 atagaaggag actgcacatg gtcatccgta cccgcccgtg gcacggcatc atggtcgcca
     8101 ccaccctccc gttccgcgac gatctctccg tcgaccacga cgcgtacgcc gcccaggtcg
     8161 cccggctgct cgctgccgac tgcgacggcg tcgtccccaa cggctccctc ggcgagtacc
     8221 agacgctgac cgacgacgag cgtgcccagg tcgtccggac cgccgtggcg gccgccggcg
     8281 cgggggaccg ggtgatgccc ggcgtctccg cgtacgacag cgccaccgcg tgccgctggg
     8341 ccgagcaggc cgccgaggcg ggcgccggat ccgtcctgct gctgccgccc aacgccttcc
     8401 gcgccgaccc ggcagcggtg cgcgcccact tcgccgaggt ggccgccgtc gggctgcccg
     8461 tcgtcgccta caacaaccct tacgacacca aggtcgacct caccccgcgc ctcctcgccg
     8521 agctgcatgc cgacggcagc atcgtcgccg tcaaggaatt cagcggcgat gtccgcaggg
     8581 cctacgagat cgccgaagtc gccccggaac tcgacctgtt gatcggcgcc gacgacgtcc
     8641 tcctcgaact cgcgctggcc ggcgcggtcg gctggatcgc gggctacccg aacgcgctgc
     8701 ccgaggcctg cggctccctc taccgggccg ccgtcgccgg ggacctggac accgcgctgc
     8761 cgctctaccg tgccctgcat ccgctgctgc gctgggactc caagcccgaa ttcgtgcagg
     8821 cgatcaagct ctcgatggac ctcgccggcc accgcggcgg tccgacccgc ccgccccgct
     8881 tcccgctccc cgccgggcag tcggcccagc tccgcgccgc caccgagaag ctcctcgccg
     8941 acggccacca ctgagaggaa acccatgcgc acccgccacg tcttccatgc cgtcgactcg
     9001 cacaccgagg gcatgcccac ccgcgtcatc accggcggca tcggcaccct ccccggcgcc
     9061 accatggccg agcgccggct gtacatggcc gaacaccgcg acgacatccg cacgctgctg
     9121 atgtacgagc cgcgcggcca tgccgccatg agcggggcga tcctccaggc accgacccgc
     9181 cccgacgccg actggggcgt gctgttcatc gaggtctccg gctatctgcc gatgtgcggg
     9241 cacgggacga tcggggtggc caccgtcctc gtcgagaccg gcatggtggc ggtgtgcgaa
     9301 ccggtgacca cggtgcgcct ggacaccccg gccgggctgg tcaccgccga ggtgcaggtc
     9361 acggacgggg cggcgacggc cgtcacgctc accaacgtgc ccgcgttctg tgccggactc
     9421 gaccgcaagg tcactgtccc cggatacggc acgctcagct atgacctcgc ctacgggggc
     9481 aatttctacg ccatcctgcc gctggacagc gtcgggctgc ccttcgaccg ggaccgcaag
     9541 aacgacatcc tgtccgccgg actcgccctc atggacgccg tgaacgccac cgaccggccg
     9601 gtccatcccg aggacgagcg gatcggcggc ctcaagcacg tctatttcgc cgcacccgga
     9661 tcgaatgcca cccgctcccg gcacgcgatg gccatccacc ccggctggtt cgaccgctca
     9721 ccctgcggta cgggcacctc cgcgcggatg gcgcagctgc atgcccgcgg ggaactcttc
     9781 ctggggcagg acttcgtcaa cgagtccttc atcgggacgg agttcaccgg gcggctcgtg
     9841 ggccggacca cggtcggcgg gcggccggcc gtcgtcccca ccgtcaccgg gcgggcctgg
     9901 gtgaccggta ccgcgcagta cttcctcgat ccggccgacc cgttccccgc ggggttcctg
     9961 ctctgaacgc cggaccgggg cggcggcttg gcaactgccg ccaccagggg gttcgcgcaa
    10021 cgtgacattg tacgctggca ctccgcagca actcggagga ccacgatggg tgaactcaag
    10081 caccgcagcc tgatcaccgc gcaggagcga cttcgcgatc aggtcgccca tcagctgcgc
    10141 gcggccctga tagcgggcga actccgcccg ggatcggtct actcggcccc gggcctcgcc
    10201 gcggacttcg gtgtctccgc caccccggtg cgcgaggcga tgctcgatct ggcccgggag
    10261 ggtctggtcg aaccggtacg caacaagggc ttccggatca ccgaggtgag cgagcgcgac
    10321 ctcgatcagt acaccgagat ccgggcactg atcgaggtcc cggtcatcgg ccaggtcacc
    10381 cgcaccgccg gccgggaaca gctcgaagcc ctccgcccgg ccgccctgga gatcgtcgcc
    10441 gccgcccgcg cacacgacct gatcggatat ctggaggccg accgccgctt ccacctcgcg
    10501 ctgctcggtc tcagcggcaa cgaccgcctc gtcgaaacgg tcggcgaact gcgcaagcgc
    10561 tcccgtctct acggcctcac ccgcctcgac gagcgcaacc agctgctgcc ctccgccgag
    10621 gaacacgtgg aactcctcga cctgatgctg accggcgatg ccgaggcggc cgaggcctgt
    10681 atggcccgcc acctcggtca tgtccgctcg ctgtgggccc aggcgcgggc ggaaccaccg
    10741 gtgccggagc tgcgcgaccg ccagggctga ccgggcccgg gacggccggg cccggggacg
    10801 gccgccgggt caggcgttcc cggccagcag cccgtccatc cactcctcga ccccgtcgac
    10861 ggtgcgcggc agcccgcccg acatcagccg ggccccgtcc gccgtgatca ccaggtcgtc
    10921 ctcgatacgg acgccgatgc cgcgcagctc ccgcggcagg gtctcgtcgt cgggctggag
    10981 atagagcccc ggctcgaccg tcagtacctg accctcggtc aggacgccgt ccagatactg
    11041 ctcggcgcgg gcccggccgc agtcgtggac atcgaggccg agcatgtggc cggaactgca
    11101 cagcgtgtag cgccggtgga gaccgctgtc ggcggcgagt gcctgtgccg ccgggatgcg
    11161 cagcaccccc cagtcggcca ggccctcggc caggacgccc gagcacgccc ggtggaagtc
    11221 gcggaagctg gcgcccggct tgagcgcggc gatccccgcg tcctgggcgg cgagcaccag
    11281 ctcgtacacc cggcgctgca cgggggagaa gcgcccggac agcggcaggg tgcgggtgat
    11341 gtcggcggtg tacagcgagt cggtctccac ccccgcgtcg agcagcagca actggtccgg
    11401 gtcgagcggg ccgtcgttgc ggatccagtg caggacacag gcgtgcgcgc cggcggcggc
    11461 gatggtctcg taccccgtgc cgttgccctc ggcgcgggcg cgcagctgga agaccccctc
    11521 gatccagcgc tcgccgcgcg ggtggcgcag cgcggcgggc agggaccgta cgacatcctc
    11581 gaagccggtg acggtgtgat cgacggcctg ctgtagctga tccacctccc aggcgtcctt
    11641 caccagccgc aactcgctga gggcggtggc gagttcggcg tcctgggcgg cattccggtc
    11701 ggacgggcgg ggcgccaggt cgtccagatg cgcacagcgc acgccggtga gctgctcggc
    11761 ctcggccaga tcggggcggc ggcccaccca gaactcgccg tacttgcggt cccggtagaa
    11821 cgcgccgtcg gcgtcccgcg gcgaccgcgg ccgcagatac agcaccgcct cgccgtccgg
    11881 ttccagcacc aggacatggc ccggctggtc ctcgccggtc agcccggtca gccaggcgta
    11941 cgcactgtgc ggccggaagc ggtggtcgca gtcgtgggag cggacccgca actccccggc
    12001 ggggacgagc agccgctcgc cggggaagcg tgcggcgagg cgggcccggc gcccggcgaa
    12061 gtgcgcgaag ccgggcacac aggtgccggc cgggagcgag ggcgtggccc atccgtcggt
    12121 catgaagtcc gcgagggcgc tcgacaccgg caagtcgtgg ctcccggtgt ggagttgggg
    12181 gtggtgcaag gtcatgtgga cacctccggg aaagaaagtt cctgaagcct tgtcagtgca
    12241 atttcacatt actatgttat gggtcacacc tcgtggagtg aagggcccct cgccttgctc
    12301 tccactctca accccccacc cccctccgga ggttcaggtg cccccttcgc atctgccgcg
    12361 caccatcctg ctggccgcga gcctcgcggc gaccctcgcc ctgcccagcg ttcagccggc
    12421 ccgggccgcc gtgtcccacc cgtccgtcct ccccgcgcga gcgcaccagg cgcaaccgtc
    12481 cgccacccgg ccgtcagttc ccaccgacaa ccccttcgat cacgcccaac gcctcacccg
    12541 ggcacccaag ttcgccgtca cgcccccgcc cgcgccccgc tccctcgtcg gaagggacgg
    12601 catcccgggc ccgcagacca gaccgccgac cgcgccgcac caggggagat ccgccgtcgc
    12661 gccctgcacc ctcgacggca tcaccggcct gagccccgag cagttcgcgg acttcctcgc
    12721 cgacccggcc gtcaccgccg acgtctgtct gcgcagcctc ctgtggacct gggacccccg
    12781 gctgatcccg gtcatgtccg acgcgcacgt ccaggccgtg gcgcgccgca tcaccggcct
    12841 ggccgcggcc cacgacggca agaacaccag ccacctgtac gagatgttca cgtacctgca
    12901 cgcggtggcc taccaggact tctcgcacga cgagatcgac accaccgacg cccccaccgt
    12961 cgacgctgta cggcgcgcgg t
//
