LOCUS       NZ_LT907981            22518 bp    DNA     circular CON 12-FEB-2024
DEFINITION  Streptomyces sp. 2323.1 chromosome I.
ACCESSION   NZ_LT907981
VERSION     NZ_LT907981.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. 2323.1
  ORGANISM  Streptomyces sp. 2323.1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 03:31:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,058
            CDSs (total)                      :: 6,971
            Genes (coding)                    :: 6,808
            CDSs (with protein)               :: 6,808
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 163
            CDSs (without protein)            :: 163
            Pseudo Genes (ambiguous residues) :: 0 of 163
            Pseudo Genes (frameshifted)       :: 64 of 163
            Pseudo Genes (incomplete)         :: 123 of 163
            Pseudo Genes (internal stop)      :: 17 of 163
            Pseudo Genes (multiple problems)  :: 37 of 163
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3713988
            Orig. end                         :: 3736506
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT907981.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22518
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="21"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22518
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22518
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12518](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12518
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    1259..1270
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.16"
                     /tool="antismash"
     misc_feature    1264..1279
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.05"
                     /tool="antismash"
     gene            complement(1391..2053)
                     /locus_tag="CPH93_RS15625"
                     /old_locus_tag="SAMN06272775_3191"
     CDS             complement(1391..2053)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604195.1"
                     /locus_tag="CPH93_RS15625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3191"
                     /product="DUF5063 domain-containing protein"
                     /protein_id="WP_093484353.1"
                     /transl_table=11
                     /translation="MSDATLHNATQDPDDFAVSISDSIESFIVAVTEVAKGDEPDSAVP
                     FLLLEISQLLLTGGRLGAHEDFVPDERYETDTGPEPDVDELRERFATLLDPVDVYSEVF
                     DPYVPRSEPVASRISDDLADIITDLRHGLAHYRAGRVSEALWWWQFSYLSNWGPTASAA
                     LRALQSLVAHVRLDQPLVELDGLDTDSDVTGDEEQLAEEAGKVMAAEIAAPLGLRGS"
     gene            complement(2046..2645)
                     /gene="recR"
                     /locus_tag="CPH93_RS15630"
                     /old_locus_tag="SAMN06272775_3192"
     CDS             complement(2046..2645)
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124031.1"
                     /locus_tag="CPH93_RS15630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3192"
                     /product="recombination mediator RecR"
                     /protein_id="WP_006604196.1"
                     /transl_table=11
                     /translation="MYEGVVQDLIDELGRLPGVGPKSAQRIAFHILQAEPTDVRRLANA
                     LMEVKAKVRFCSVCGNVAQEEQCRVCLDPRRDPAVICVVEEPKDVVAIERTREFRGRYH
                     VLGGAISPIEGVGPDDLRIRELLARLADGTVTELILATDPNLEGEATATYLARMIKPMG
                     LRVTRLASGLPVGGDLEYADEVTLGRAFEGRRLLDV"
     gene            complement(2697..3047)
                     /locus_tag="CPH93_RS15635"
                     /old_locus_tag="SAMN06272775_3193"
     CDS             complement(2697..3047)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010985981.1"
                     /locus_tag="CPH93_RS15635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3193"
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="WP_093484352.1"
                     /transl_table=11
                     /translation="MIPGGQPNMQQLLQQAQKMQQDLAAAQQELAETPVEGSAGGGLVK
                     ATVTGSGELTGLVIDPKAVDTDSAEETAETIADLVLAAVRDANASAQQLQQQKLGPLAQ
                     GLGGGGIPGLPF"
     gene            complement(3207..5696)
                     /locus_tag="CPH93_RS15640"
                     /old_locus_tag="SAMN06272775_3194"
     CDS             complement(3207..5696)
                     /EC_number="2.7.7.7"
                     /GO_component="GO:0009360 - DNA polymerase III complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521920.1"
                     /locus_tag="CPH93_RS15640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3194"
                     /product="DNA polymerase III subunit gamma and tau"
                     /protein_id="WP_096213201.1"
                     /transl_table=11
                     /translation="MSSLALYRRYRPETFAEVIGQEHVTDPLQQALRNNRVNHAYLFSG
                     PRGCGKTTSARILARCLNCEQGPTPTPCGTCQSCVDLARNGRGSIDVIEIDAASHGGVD
                     DARELREKAFFGPASSRYKIYIIDEAHMVTSAGFNALLKVVEEPPEHLKFIFATTEPEK
                     VIGTIRSRTHHYPFRLVPPGTLREYLAEVCGREDIPVEDGVLPLVVRAGAGSVRDSMSV
                     MDQLLAGAGADGVTYAMATALLGYTDGSLLDSIVEAFAAGDGAAAFEVVDRVIEGGNDP
                     RRFVADLLERLRDLVILAAVPDAGEKGLIDAPADVVERMTAQASVFGAAELSRAADLVN
                     TGLTEMRGATSPRLQLELICARVLLPAAYDDERSVQARLDRLERGAGAALLGGAGGTGG
                     GAGSGGELGPGAAPVVASGGGPAAGYVPGPEAHPAMPAGGPSGPAAARAAVRGATSAGQ
                     GGGAPAPAAPGAQTAGTGASGGPGAGPGGEQHGGGAGAPQGAPAEAQQPPGQDGGSAGA
                     GAAARPGAWPGSTSRANGADSGSGAAGGGAGRQPGGWPTAVAPGQGGAPAPSAPAPSAP
                     PAPSGPPAGPPAPASPQPPQAAGTAPGAAQGAAQVRQMWPDILEAVKDRRRFTWILLSQ
                     NAQVSGFDGTTLQIGFPNAGARDSFANGGSEDVLKDVLAERFQVQWRVEAIVDPSGGAS
                     PPAGGAPRSGGGGFGGGAPAAPQQGAPQPPPQQSGPAAPPSSGGRYGAGGEGSGGGGSQ
                     GARMAREAVSPAASAGGAQGGPVAEPSYTPPEPPPTSIEYDMPAEDDADLVDSALSGHD
                     LIVRELGATVLEEFNNE"
     ncRNA           complement(5742..5840)
                     /db_xref="RFAM:RF00169"
                     /gene="ffs"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /locus_tag="CPH93_RS15645"
                     /ncRNA_class="SRP_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="SAMN06272775_3195"
                     /product="signal recognition particle sRNA small type"
     gene            complement(5742..5840)
                     /gene="ffs"
                     /locus_tag="CPH93_RS15645"
                     /old_locus_tag="SAMN06272775_3195"
     tRNA            5972..6059
                     /anticodon=(pos:3719994..3719996,aa:Ser,seq:gga)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="CPH93_RS15650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SAMN06272775_3196"
                     /product="tRNA-Ser"
     gene            5972..6059
                     /locus_tag="CPH93_RS15650"
                     /old_locus_tag="SAMN06272775_3196"
     gene            6401..7531
                     /locus_tag="CPH93_RS15655"
                     /old_locus_tag="SAMN06272775_3197"
     CDS             6401..7531
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131317.1"
                     /locus_tag="CPH93_RS15655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3197"
                     /product="hypothetical protein"
                     /protein_id="WP_096213202.1"
                     /transl_table=11
                     /translation="MLARRLLRTAAAAALTLAAALVPADGAGAAGAAPRWEVSFPGDSP
                     GSLLSVSAVHDDLAWAVGRKAQHGVIMRWDGKKWREDAAPGLPRVQEWSSVSAVSADDV
                     WAYGLAGRGQALVHYDGKRWTRVPTTGPFDDSWPEVSIKAVPGRLFKGGKSLYTYAKGT
                     WKTFALPHLVDIRDIDALAADDAYATGMQYPVDGGHPVIYHWDGTTWTLMETPPVRTGT
                     DTAKITVASRGSVYVAGWAQGSHGGPPVPSVVHWNGSAWKDVTGSLADLWLTEIESDGH
                     GGLWVTGTDRTEPVTAAPVFWHYDGTGWTKMPGALAPDGDHESPRYAFYDMEPSGSSGA
                     YWAVGDYSMPMTKESDTPINGLIERSTPHPPAATHK"
     misc_feature    6419..6421
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7782..9080
                     /locus_tag="CPH93_RS15660"
                     /old_locus_tag="SAMN06272775_3198"
     CDS             7782..9080
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540831.1"
                     /locus_tag="CPH93_RS15660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3198"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_096213203.1"
                     /transl_table=11
                     /translation="MPDQPSSRGVLADWFRGHAATLNTLDPHQPMDDLEPLREIVGSAR
                     VVAVGENAHFVEEFSRPRQRVLRFLAERCGFTVLALEFGFSEAFRLEPWLQGEGDDAGL
                     AKVSAAAADWGAADLMHWLRHHNRTSGHPFRFAGIDVPEAGGQLRPALDPVADYLHEVD
                     PDALPLLDTVLEISDRFLDGSGSGAAAAPAWARLDPAEQNALTAALARLLLRLRGAEPL
                     YVRRSSQRRFDIARRRVEAACHTDYMFHAMAALLSGRGSGADLSVREIYMAESVRWHLD
                     RAAPGTRMALVSHNAHIQKTPASFGGALTALPMGHHLQRMLGEDYCSVAVTHTTDHVPE
                     MYPDESARVGFTLADAQLEPAEFGSVEAALIDAGLGDGITLTDLRRSPRDAHGVPLLNR
                     IRSQSSSLCAPIPEAFDAVLAVPTVTRDRTVRF"
     misc_feature    complement(9555..9568)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.83"
                     /tool="antismash"
     misc_feature    9593..9608
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    complement(9666..9675)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.08"
                     /tool="antismash"
     gene            9685..9819
                     /locus_tag="CPH93_RS35425"
                     /old_locus_tag="SAMN06272775_3199"
     CDS             9685..9819
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123197.1"
                     /locus_tag="CPH93_RS35425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3199"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_107452766.1"
                     /transl_table=11
                     /translation="MTEQSEQTPTEYIPPMLVEVGEFTEDTLGNWHGTSPDWFFNYYW"
     CDS_motif       9685..9768
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MTEQSEQTPTEYIPPMLVEVGEFTEDTL"
                     /locus_tag="CPH93_RS35425_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9769..9819
                     /prepeptide="core"
                     /locus_tag="CPH93_RS35425_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="4.50"
                     /molecular_weight="2059.1"
                     /monoisotopic_mass="2057.8"
                     /core_sequence="GNWHGTSPDWFFNYYW"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MTEQSEQTPTEYIPPMLVEVGEFTEDTL"
                     /leader_location="[9684:9768](+)"
     gene            10001..11824
                     /locus_tag="CPH93_RS15665"
                     /old_locus_tag="SAMN06272775_3200"
     CDS             10001..11824
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_096213204.1"
                     /locus_tag="CPH93_RS15665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3200"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_096213204.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.3e-39, bitscore:
                     135.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLPDTADGAEIRALVPFAHARVIAHASGRPWLVGEWSHGQVRVA
                     SAGPVRLAVSGTCPVTDDGLARIAARISRLSDVDRAVPALLGSCHVVASVDGHVRFQGS
                     ASGLRRVFHTRVNGVRVAADRSDVLAAMTGAGVDEETLALHVACGLQVPFPANARSAWS
                     GIGTLAPENCLLWEDDRDREAVWWRPPEPDRSLREGTAAVRDTLTAVVDRRAPGEGRLS
                     ADLSGGLDSTSLCFLAARHTPELLTFRWGEADAGNDDAVYAGQAARLLDRAEHLVVPQH
                     ELPDIFADPAIAVSAEEPLSLTRATARIRRGARLLADRGSRRHLAGHGGDELFSPMPSY
                     LHQLMRRHPVTALKHVRAHCALKRWPLRATLGELAQPGSLPAWWREQAGLLTEPRPPLR
                     RPALGWGLGPVRAAPWMTPEGVELAREALRRTADQAQPLAEDLATHTMVLMIRSNTASY
                     RLLARLYAESGVELDMPYLDDTVIDAVLRVPAHEHAGPWRYKPLLADAMHGIVPDGIRA
                     RTTKGEFGEDIRRGLRRNLPAILDLFADSELAARGLIDTGALRLRLGGPQPDNTTAQAL
                     ESLLGCETWLRTTSGPGTLPRAGNGTVPSEV"
     aSDomain        11830..12006
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CPH93_RS15670_Lasso_Fused_RRE.1"
                     /evalue="6.90E-10"
                     /identifier="RREFam003.1"
                     /label="CPH93_RS15670"
                     /locus_tag="CPH93_RS15670"
                     /protein_end="59"
                     /protein_start="0"
                     /score="29.9"
                     /tool="antismash"
                     /translation="MRLHPDVSMTDTDDGTVLLHQRTGRYWQLNVTGSRVLHRLLDGDT
                     PESIADGLAAAHGI"
     aSDomain        11830..12072
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CPH93_RS15670_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.40E-27"
                     /identifier="RREFam002.1"
                     /label="CPH93_RS15670"
                     /locus_tag="CPH93_RS15670"
                     /protein_end="81"
                     /protein_start="0"
                     /score="85.8"
                     /tool="antismash"
                     /translation="MRLHPDVSMTDTDDGTVLLHQRTGRYWQLNVTGSRVLHRLLDGDT
                     PESIADGLAAAHGIDPQRARQDVGAVIEQLRTAELT"
     gene            11830..12084
                     /locus_tag="CPH93_RS15670"
                     /old_locus_tag="SAMN06272775_3201"
     CDS             11830..12084
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604203.1"
                     /locus_tag="CPH93_RS15670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3201"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_093484347.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6.1e-25,
                     bitscore: 85.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 1.7e-07,
                     bitscore: 29.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4e-13, bitscore: 48.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLHPDVSMTDTDDGTVLLHQRTGRYWQLNVTGSRVLHRLLDGDT
                     PESIADGLAAAHGIDPQRARQDVGAVIEQLRTAELTVAS"
     gene            12081..12518
                     /locus_tag="CPH93_RS15675"
                     /old_locus_tag="SAMN06272775_3202"
     CDS             12081..12518
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604204.1"
                     /locus_tag="CPH93_RS15675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3202"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_173909820.1"
                     /sec_met_domain="PF13471 (E-value: 6.5e-28, bitscore: 95.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSMALDQRARLPLLRRLLPLLAVGAARPLARLKPARLRAVLEF
                     ARRGAAPADAGQAQRARDQVVAVSLRCAGQNCLQRSLATALLCRARGVWPTWCTGVRTH
                     PFAAHAWVEAEGRLIGEPHPEGYYKPLLTVPPRTGAGAGDR"
     gene            12641..13270
                     /locus_tag="CPH93_RS15680"
                     /old_locus_tag="SAMN06272775_3203"
     CDS             12641..13270
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604205.1"
                     /locus_tag="CPH93_RS15680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3203"
                     /product="hypothetical protein"
                     /protein_id="WP_093484345.1"
                     /transl_table=11
                     /translation="MTTVHTDGAPRPAAGALRLVESRTTRPTTVDFAEYVQAMSVHCPY
                     LAPSVEHGLTGWTVYEAAGEAPEVEAEVFHAGVRAAEWVRTQLNGPRGALVCENIAVIG
                     AGREVLAWPHWALKNLYGPVGVMFGKFPVGDQVTDHRGRLVPEPPVSFLAVRVAVRARD
                     PLFLSRTPDLAALVAEAADDGRDVFGELSHEWKDVKLWAQRRLPQR"
     gene            complement(13286..13801)
                     /locus_tag="CPH93_RS15685"
                     /old_locus_tag="SAMN06272775_3204"
     CDS             complement(13286..13801)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604206.1"
                     /locus_tag="CPH93_RS15685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3204"
                     /product="Pycsar system effector family protein"
                     /protein_id="WP_096213206.1"
                     /transl_table=11
                     /translation="MTTHRGDATAGHGGALIRTLITETREELQKADSKAGMMLTALGVA
                     LTALLGAISAGGITPQLYAPVPQALFWTGCAAWVPALVLLGLAVAPRPGTPQRRRAHYF
                     GDATVTASVRRLAAVVQRTDPEDRDLNQFVTLSRTVWVKYRCIRHGMAWGAVFVVLTSL
                     GLLTGSSL"
     gene            complement(13885..15189)
                     /locus_tag="CPH93_RS15690"
                     /old_locus_tag="SAMN06272775_3205"
     CDS             complement(13885..15189)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604207.1"
                     /locus_tag="CPH93_RS15690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3205"
                     /product="DUF4407 domain-containing protein"
                     /protein_id="WP_096213207.1"
                     /transl_table=11
                     /translation="MTDSPTPYRDAFARLDPARRLRALTGVDEDLLAKVGYERSRYTAL
                     GGVVLGTSVIAAFSMWNFATEALGRVSLLAVIPTVIWMLFILNLDRWLVTPQPNARRRA
                     GPLLLRLLIALVLGAVVAEPLVLRIFATAVEERIAGERNTDLDQLRGNLLRCNPVPSAT
                     EASSPAGCGRYVLSFGATPGGQSDELSALRAESGALQKRVDQDNDALDTLDGEVRNECR
                     RLIRIASTGLYSRTSECLRMREKAKDYRSTHRTGENERRLAAMHGRIAAMEGKVTASRG
                     TFLQARAAGIERRLAKERAKQKEIGVLERMGALDGLAGKNTVLFAGIWLVRALFVLLDA
                     LPVLVKFLSGESAYDRMLTSESNSAVKIHGEQVRLTERRAMADIEIAQEAIEQEVRRSR
                     AESEAAHRELVATVNIRLRKAVNGLEQELRNTSGV"
     gene            complement(15182..16234)
                     /locus_tag="CPH93_RS15695"
                     /old_locus_tag="SAMN06272775_3206"
     CDS             complement(15182..16234)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604208.1"
                     /locus_tag="CPH93_RS15695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3206"
                     /product="hypothetical protein"
                     /protein_id="WP_096213208.1"
                     /transl_table=11
                     /translation="MNYPVVAEHVLGTVQGNWWSRRRRRDDVPPLPPGAVYVFRVGGNY
                     RQFPEGMVFDPSHADVLDASSVSLVDTRARMVEVDRTVPSVSEADHFTLRASFACQVTD
                     PTVVARQGIIDVTVPLRAYLAGDSELPRVSAGHRVEEVNAVRREVSHRMTAYSAIVAPR
                     VAGMSVEFVSAEVHASDDLRTWEQKMRDERRSQELRRGQRDFETQDTQRIAELLSQGSD
                     YADAFGIARNRIDVAQAAARIHRTTDEDASRRHRAADEDRAHARARETAEAQMRRDMVL
                     TLLRQMGAAEDYVDYHQVLEQVLRDGGGPGVPAVGPGPQSPGSEAPRRLNSGAGRPQDG
                     FVQDEDDLVD"
     gene            complement(16366..18531)
                     /locus_tag="CPH93_RS15700"
                     /old_locus_tag="SAMN06272775_3207"
     CDS             complement(16366..18531)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604209.1"
                     /locus_tag="CPH93_RS15700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3207"
                     /product="hypothetical protein"
                     /protein_id="WP_096213209.1"
                     /transl_table=11
                     /translation="MADDAGAPDLSEPPVPGPEDELRQEQPEDDAPADRTDAGGASGAD
                     CDERKEREEDGKGYDDLRQVLGQRVYNNFYGVVDASGAAFGFGAAAAPGLAPGFVEPDE
                     VDRALRCYLSPRPCFDDALGTLRAEHLVVLAGPDSSGRGAGAFALLQRVRGVHTGLRSL
                     SPANSLAELAASSALKAGQAYVILDYVGEMNVDAVQAFEIRRLSEELRRKGSYLVITAP
                     EAARRRLALKDHCVPWAAPDPLELFHHCRHLTSQAGLPPEVAEELQERVAELRRPADVV
                     AAVTGLADGPDAALKMLRDSERERVRNWFRTEPSAGDLLPLAALAFLEGIPERNFEKAS
                     VLLGMHVRDWEQTGETPAAEPEATGTTALRGVTFEQTRARWKERATGLVRTERRAGPGQ
                     DPSRSERRIVFTSPRVRALVIGELHDLYGYELWYPVRQWLSELSRLADLDVRTEVARGV
                     ALYARHALAEVDENLLRVWADGLAAQRVTTALTLQFMCDDQHLAPQALNLALSWAERKG
                     PARAVTTAMALTGTLGSLYRLEALNWLWFLTQRGERMAFAARRSLVLLLQTAEQDPERA
                     LFTLRYVRTRIADTAQRSKARSLALRTTVQLLEAERLEGSGVLAAALLRDVPGSARQLG
                     LLWVSVLLSVCRRGAVRALCRTLADLRDDPSAAAAVRALGEAMRSAMTPRQWQALGNDL
                     PHALRHPEYAIPGTRRLAQVLLGSLRG"
     gene            complement(18524..19288)
                     /locus_tag="CPH93_RS15705"
                     /old_locus_tag="SAMN06272775_3208"
     CDS             complement(18524..19288)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604210.1"
                     /locus_tag="CPH93_RS15705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3208"
                     /product="hypothetical protein"
                     /protein_id="WP_096213210.1"
                     /transl_table=11
                     /translation="MAEWSGFYPCTCIAVDAQAYGGNNDRRQSEIQHDLPRILSRAARG
                     TGLDRSQWHIQPKGDEELAVHPMDGTEPRLVDDFVRHLVAELREYNGLRVPTARMRLRA
                     AIHHGPVELADNGFAGSTVVTTARLLSSRHLYDALRTNEGADLALLLSDDVYRSTVAGG
                     HTTLSAADFRRVTVREKECEAVGWLQVPGHEAPHPAAHGPAAERPQPPTDGAPGDGSAA
                     RHDYRGEQISVNHFTAPVDLRGGVVGFGSAGG"
     gene            complement(19370..20077)
                     /locus_tag="CPH93_RS15710"
                     /old_locus_tag="SAMN06272775_3209"
     CDS             complement(19370..20077)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004985308.1"
                     /locus_tag="CPH93_RS15710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3209"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_231977357.1"
                     /transl_table=11
                     /translation="MKHAWPHSTFLGRLRSSTLEELMGLGTPMVYPAHRQLLQQGDESR
                     HVLLLTRGVAKVVASSESGYEMLLAIRVGGDLIGEMAAFEDQPRSGTVIACSEMSARII
                     QLTALESFLGRHPDAMRAMLAMLCARLRWANRRRMDFRAYDSLTRLARVLAELSQAYGN
                     EVLDGSARRQILDVTLNQAELASLAGLALPTTEKALASLSKLGLVERSYRKITVCDVSK
                     LLVFAKVFQENPY"
     gene            complement(20366..22024)
                     /locus_tag="CPH93_RS15715"
                     /old_locus_tag="SAMN06272775_3210"
     CDS             complement(20366..22024)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604212.1"
                     /locus_tag="CPH93_RS15715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3210"
                     /product="APC family permease"
                     /protein_id="WP_096213211.1"
                     /transl_table=11
                     /translation="MTRPAAAGNAGAAGTRHLRRAVGFWGLMFISLGSIIGSGWLLGAL
                     TTAVIAGPASLISWVLASAMLAVLALAHAELGATYPIAGGTARFPFFAFGPLVGFTAGW
                     MSWLRSVLIAPIEVEATLSYLDRIGWVRDRVHLLHPNGTLTAAGLVIGTFFMLLFTLIN
                     VLGVRLLAGINSVTAVVKTAVPLLTVVVLMTLAFHGSNFTAGGGFAPHGAHGVFAALPA
                     GVVFALLGFEQAIQLAGEARDPQRDVSRAVIVAMAIGTALYLLLQVAFIAALDPTALTH
                     SWDNPVGKGNFGPYATLATAVGAGWLATILYVDAVISPAGTGLVYMAGAARLSYAMGRE
                     RVLPRPLSQVGRSRVPVVSILLAFVVGELAFLPFPSWQALVGLVTSAAAIMYAFAPVSL
                     HALRVRDAGRNRPYRLPRGTAMAPAGFVFANLIFYWSGYEADWKLGTAALLGFVVFALT
                     RRGIPAAERSVLRGRSAAWVWPWLGGMVLIGRFGRYGGTRALPAWWDLVIVIVFSLVIH
                     YTAVHLAMPPEAVDEAVEHEEEGESVPPPAAASGR"
ORIGIN
        1 gggtcttctc cagggccgcg acggccttgc ggccctccgt cttgggcagc gtgaaggaga
       61 tgtcggtcag accggtcgac gcggcggaca cgttctgcac gaccatgtcg atgttgacct
      121 cggagtccgc gatcgcacgg aagatgcgcg cggcctcgcc cggcttgtcc gggactccga
      181 cgaccgtgac cttcgcctcg gaggtgtcat gtgcgacgcc cgagatgatt gcctgctcca
      241 tcggctggtc cccttgcggt tcgttgctga cccacgtgcc ctgcagcccc gagaaggacg
      301 agcggacgtg gatcgggatg ttgtaacggc gtgcgtactc gacgcagcgg tgcagcagca
      361 ccttggagcc ggagctggcc agctccagca tgtcctcgaa ggagatccag tcgatcttcc
      421 gggccttctt cacgacccgc gggtcggagg tgaagacacc gtccacatcg gtgtagatct
      481 cacagacgtc ggcgtccagg gcggccgcca gcgcgacggc ggtcgtgtcc gacccgccgc
      541 gccccagcgt cgtgatgtcc ttcttgtcct gggacacgcc ctggaagccg gcgacgatgg
      601 cgatattgcc ctcgtcgacg gaggtcttga tccggcccgg cgtgacatcg atgatccgtg
      661 ccttgttgtg cacggagtcg gtgatgacac cggcctggct accggtgaag gactgcgcct
      721 cgtgaccgag gtttttgatc gccatcgcca gcagggccat ggagatccgc tctccggcgg
      781 tcagcagcat gtcgaactcg cgccccgacg gaatcgggga cacttcctgc gcgagatcga
      841 tcagctcgtc cgtcgtgtcg cccatcgccg aaaccactac gacaacctgg ttgccgttct
      901 tcttggcctc gacgactcgc ttggcaacgc gcttgatgcc ctcggcatcc gcaacggatg
      961 agccgccgta cttctgcacg acaaggccca cgtgcgctcc tcgcaactgt ctcatcggga
     1021 gtttcctccc ggacccccgg aaatgggggt actgcggtcg gctcagtcta acgagcaagc
     1081 ggaatccgcc ctgctgatat cgcatcgtga gacacgcgac tcactgtttg accaccgtga
     1141 tcgccttgat caccatggcc acctgaactc gtgagttccg cgtcccgcgg gcggtatcca
     1201 cacggcgcac cgttgcgcct gctcggcgag cacatgcccg ctccaggccg gtacacacga
     1261 aaacgtaacc cagctcacag gctccggcca cggcgcgagg catcacgggg cagctggcgt
     1321 caggcgcctc gtgcgccccg gcggcgggcg acggccgggt cgtgcccggc cgcggcggcc
     1381 gcccccgggc tcagcttccc cgcagcccca gcggcgccgc gatctccgcc gccatgacct
     1441 tcccggcctc ctcggcgagc tgctcctcgt cgccggtgac gtcgctgtcg gtgtccaggc
     1501 cgtccagctc gaccagcggc tggtcgaggc gtacgtgggc gaccagcgac tgcagcgcgc
     1561 gcagtgcggc cgaggcggtc gggccccagt tggagaggta ggagaactgc caccaccaca
     1621 gggcctcgct gacccggccc gcccggtagt gcgccaggcc gtggcgcaga tcggtgatga
     1681 tgtcggccag gtcgtcggag atccggctgg cgaccggctc gctgcgcggc acatacgggt
     1741 cgaagacctc ggaatagacg tccaccgggt cgagcagggt cgcaaagcgc tcgcgcagct
     1801 cgtcgacgtc cggttccggg ccggtgtccg tctcgtaccg ctcgtcgggg acgaagtcct
     1861 cgtgggcgcc cagacggccg ccggtgagca gcagctggga gatctccagc agcaggaagg
     1921 gcaccgcact gtccggctcg tcgcccttgg cgacctcggt caccgcgacg atgaaactct
     1981 cgatcgagtc ggagatcgat acggcgaagt cgtccgggtc ctgtgtcgcg ttgtgcagcg
     2041 tggcatcaga catcgagaag tctcctccct tcgaaggccc gcccgagcgt gacctcatct
     2101 gcgtactcca gatcgccccc gaccggcagt ccgctcgcca gtcgcgtcac tctcaggccc
     2161 atgggtttga tcatgcgggc cagataggtg gccgtggcct cgccctccag attcgggtcg
     2221 gtggccaaaa tcagctcggt gacggtgccg tccgcgagcc tggccagcag ttccctgatc
     2281 cgcaggtcgt cggggcccac gccctcgatc gggctgatcg ccccaccgag gacgtggtag
     2341 cgaccgcgga actcgcgcgt ccgctcgatc gccacgacgt ccttgggctc ctccacgacg
     2401 cagatgaccg ccggatcgcg cctcggatcc aggcagaccc ggcactgctc ctcctgcgcc
     2461 acgttgccgc agacgctgca gaaccggacc ttcgccttga cctccatcag cgcgttcgcg
     2521 agccggcgga catcggtcgg ctcggcctga agaatgtgga aggcgatccg ctgcgcgctc
     2581 ttgggaccga cgccgggcag cctgcccagc tcgtcgatca ggtcctggac cacgccttca
     2641 tacacggaac gtcttctttc tcttctgccg tgctgcgtac gctagttggc tactcctcag
     2701 aaggggagac ccgggattcc gccaccgccc agaccctggg cgagcggacc gagcttctgc
     2761 tgctgcagct gctgggcgct ggcgttggcg tcccggaccg ccgccaggac gaggtcggcg
     2821 atcgtctcgg ccgtctcctc cgcggagtcg gtgtcgaccg ccttggggtc gatgaccagg
     2881 cccgtgagtt caccggagcc ggtcaccgtg gccttgacca ggccgccgcc cgcggaaccc
     2941 tcgacgggtg tctccgcgag ctcctgctgg gcggccgcga gatcctgctg catcttctgg
     3001 gcctgctgaa gcagctgctg catattgggc tgaccaccgg ggatcacgac gtgactcctg
     3061 ccatacgaca acgattggtg cggtagcccg agcctacgtg tttcacgggc cccgcgccct
     3121 acgccgtagg gaggagcacg ggtgtacgcc cggtggacat ccgctgacct gctttgcggc
     3181 ccgcccgggg cgcttgtggg cgccgtctac tcgttgttga actcttccag caccgtcgcg
     3241 ccgagctcgc ggacgatcag gtcgtgaccg ctgagcgcgg agtcgacgag atcggcgtcg
     3301 tcctcggccg gcatgtcgta ctcgatcgac gtcggcgggg gctccggcgg cgtgtacgag
     3361 ggctccgcca cgggcccgcc ctgggcgccg cccgcggacg ccgccggcga cacggcctcc
     3421 cgggccatcc gcgcgccctg gctgccgcca ccgccggacc cttcgccgcc cgctccgtac
     3481 cggcccccgg acgacggggg cgcggccggg ccgctctgct ggggcggcgg ctgcggggcg
     3541 ccctgctggg gtgcggcggg ggctccgccg ccgaagccgc caccgccact acggggggca
     3601 ccgccggccg gcggactggc gccgcccgac gggtcgacga tcgcctcgac ccgccactgc
     3661 acctggaacc gctcggccag cacgtccttg aggacgtcct cgcttccgcc gttggcgaag
     3721 ctgtcgcggg cgccggcatt ggggaagccg atctgcagcg tcgtgccgtc gaagccggag
     3781 acctgggcgt tctggctcag caggatccag gtgaagcgcc ggcggtcctt caccgcttcc
     3841 aggatgtccg gccacatctg ccgtacctga gcggcaccct gcgccgctcc cggggccgta
     3901 ccggcggcct gcgggggctg cggcgatgcg ggcgcgggcg ggccggccgg gggtccggac
     3961 ggggcggggg gcgcggacgg ggcgggcgcg gagggggcgg gcgcgccgcc ctgccccggt
     4021 gccacggccg tgggccagcc gccgggctgc cgtccggcgc ccccgccggc cgctccgctt
     4081 ccgctgtcgg cgccgttggc cctgctcgtg ctgcccggcc aggccccggg ccgggccgcc
     4141 gcaccggcac ccgcgctgcc gccgtcctgc ccagggggct gctgcgcctc cgccggggcg
     4201 ccctgcggcg cccccgcgcc tccgccgtgc tgctccccgc caggcccggc ccccgggccg
     4261 ccagacgccc ccgttcctgc cgtctgcgcc cccggagcgg ccggggcggg ggcaccgccg
     4321 ccctggccgg cgctcgtcgc gccccgcacc gcggctcgcg ccgcggccgg accggacggg
     4381 cctccggccg gcatcgccgg atgagcctcc ggccccggga catagcccgc tgccggcccg
     4441 ccaccggatg ccaccaccgg cgcggccccg ggcccgagct ctcccccgga gcccgcaccg
     4501 ccgcccgtgc cgccggcccc gcccagcagc gcagcacccg cgccgcgctc caggcggtcc
     4561 agccgcgcct gcaccgaccg ctcgtcgtcg tacgccgccg gcagcagcac ccgcgcgcag
     4621 atcagctcca gctgcagccg cggcgaggtc gccccgcgca tctccgtcag gcccgtattg
     4681 accaggtcgg cggcccggct cagctccgcc gccccgaaga cggacgcctg cgccgtcatc
     4741 cgctccacca catcggcggg ggcatcgatc agccccttct cccccgcgtc cggcacggcc
     4801 gccagaatca ccagatcccg cagccgctcc agcagatccg ccacgaagcg ccgggggtcg
     4861 ttgccgccct cgatgacccg gtccacgacc tcgaaggccg ccgcgccgtc ccccgcggcg
     4921 aaggcctcca cgatcgaatc cagcagcgat ccgtcggtgt agcccagcag cgccgtcgcc
     4981 atggcatatg tcacaccgtc cgcaccggcg ccggcgagca gctggtccat cacggacatc
     5041 gagtcccgca ccgacccggc gccggcccgc accaccagcg gcagcacccc gtcctcgacc
     5101 gggatgtcct cccggccgca cacctctgcc aggtactccc gcagcgtccc cggcggcacc
     5161 agccggaacg ggtagtgatg cgtacgcgac cggatcgtcc cgatgacctt ctcgggctcg
     5221 gtggtcgcga agatgaactt cagatgctcc ggcggctcct cgacgacctt gagcagggcg
     5281 ttgaagcccg ccgaggtcac catgtgcgcc tcgtcgatga tgtagatctt gtaccggctg
     5341 ctggccggcc cgaagaacgc cttctcgcgc agctcacggg cgtcgtcgac gccaccgtgc
     5401 gacgccgcgt cgatctcgat cacatcgatc gagccccggc cgttcctggc caggtccaca
     5461 cacgactggc acgtcccgca gggggtggga gtgggacctt gctcacagtt gaggcagcgc
     5521 gccaggatcc gcgcactcgt cgtcttgccg caaccacgcg gcccactgaa cagataggcg
     5581 tgattgaccc gattgttccg caatgcctgc tgcagcggat cggtcacgtg ctcttgcccg
     5641 atgacctcgg cgaaggtctc gggccggtag cggcggtaca gcgcaaggga cgacacgcat
     5701 acgacgatat cgggccccac tgacaaccga ccggccccac aaacgcaagc gccccccacg
     5761 cacccgccag agccgaccta cccttgctgc cttccggccc tgggggagtt cagtcagata
     5821 gcgccacgtg aggggctgcg caccacacta gctgattccc cgcccgagaa acgacccgta
     5881 ccccctcccc cgacccactc caccctctcc cggaccccct cctccggatc atgttcgcga
     5941 gcactcccca acgtcttgta ttgtttgcgg cggaggattc gcctagtggc ctagggcgca
     6001 cgcttggaaa gcgtgttggg ggcaacccct cacgagttcg aatctcgtat cctccgccag
     6061 tgcctcaccg ggcacaacgt cgaagggccc caccgcttgc ggtggggccc ttcgcggttc
     6121 tccgccccgg ttctcgtccg cgttctcgtc tcagtcggcc tccggggtgg cgcccagaga
     6181 gcgtctccga tcttccgcac gactttccgg agcatcggca tcggacccgt gatgcgcatg
     6241 gcaccgagcc gggccacgcc ccccagggtc gggagcgcag gcctggcgcg ttcactacaa
     6301 ccttccgacg ccgtagccgg tctggctcgt cgtccagctg cgctccggcc tgtacgaagg
     6361 ccacttgcgc agaactcttc ccgcggagga tcgctcaccg atgcttgccc gtcgcctgtt
     6421 acgcaccgcg gccgctgccg cactgactct tgccgctgcc ctggttcctg cggacggggc
     6481 cggggcggcc ggcgcagccc cccgctggga ggtctcgttc cccggagaca gccccgggtc
     6541 cctgttgtcg gtctccgccg tacatgacga cctggcctgg gcggtcggcc ggaaggcgca
     6601 gcacggcgtc atcatgcgct gggacgggaa gaagtggcgc gaggacgctg cccccgggct
     6661 tccccgggtt caggagtggt cgtcggtcag cgcggtgtcc gccgacgacg tctgggctta
     6721 cggcctggcg ggcagggggc aggcgctcgt gcactacgac ggcaagcgct ggacccgggt
     6781 gcccaccact ggccccttcg acgactcctg gcccgaggtc tcgatcaagg ccgtccccgg
     6841 gcggctcttc aagggcggca agtccctgta cacgtatgcc aagggcacct ggaagacctt
     6901 cgcgctgccg cacctcgtcg acatccggga cattgacgcg ctggccgcgg atgatgccta
     6961 tgcgacgggc atgcagtacc cggtggacgg cggccacccg gtgatctacc actgggacgg
     7021 gaccacctgg acactgatgg agacaccccc ggtgcggacc ggtacggaca ccgccaagat
     7081 caccgtggca tcccggggga gcgtctacgt ggccgggtgg gcccaaggct cccacggtgg
     7141 cccgcccgtt ccgagcgtcg tgcactggaa cggcagcgcc tggaaagacg tcaccggatc
     7201 gctcgccgac ctctggctca cggagatcga atccgacggc cacggcggcc tgtgggtcac
     7261 cggcaccgac cggaccgagc cggtcacggc cgctccggtc ttctggcatt acgacggcac
     7321 cggttggacc aagatgccgg gagcactggc acccgacggc gaccacgagt ctccgcgtta
     7381 cgccttctac gacatggaac cgagcggcag ttcgggtgct tactgggccg tgggggacta
     7441 ctccatgccg atgaccaaag agagcgatac accgatcaac ggcctgatcg agcggtccac
     7501 gccacacccg ccggcggcga cccacaagtg acgggcccac cagggcaatc gaagcagttg
     7561 tggctggatt taatcgcctg cgtgggaagg ggcggcggct ctacgctgcg gtcatggcag
     7621 taggcagcaa attcctctga cgaggttcat cgacaggcgt agcacgccgg tggccgaggg
     7681 gcccggcgtc gattgcgcgt atgcagcgtc gcgttgttgc tcgtccgttg tgcggacgag
     7741 caacgttcct gaacctcttt acgcacgaag tgagccttcc catgcctgat cagccttctt
     7801 cccgcggcgt gctcgccgac tggtttcgcg ggcacgccgc cacactgaac acccttgatc
     7861 cgcaccagcc catggacgat cttgagccgc tccgggagat cgtcggcagc gcccgcgtcg
     7921 tcgccgtggg cgagaacgcc cacttcgtcg aggagttctc ccgcccgcgc cagcgggtgc
     7981 tgcgattcct cgccgagcgt tgcggattca ccgtcctcgc cctcgaattc ggcttcagcg
     8041 aagccttccg gctcgaaccg tggctgcagg gcgaggggga cgacgccggg ctggcgaagg
     8101 tgagtgcggc cgcggccgat tggggtgccg cagacctcat gcactggctg cgccatcaca
     8161 accgcaccag cggccatccc ttccgctttg ccggcatcga cgttcccgaa gccggcgggc
     8221 aactacggcc cgcgctggat ccggtggccg actatctgca cgaggtcgac cctgacgcct
     8281 tgcccctcct ggatacggtc ctggagatca gcgatcgctt cctcgacgga tccgggtccg
     8341 gcgccgcggc ggcgcctgcg tgggcgcgcc ttgaccccgc cgagcagaac gcgctgaccg
     8401 ccgcgctggc gcggctgctg ttgcggctac ggggcgccga accgctctac gtccgccgaa
     8461 gcagccaacg ccgcttcgac atcgcccggc gccgggtgga agcggcgtgc cacaccgact
     8521 acatgttcca tgcgatggcc gccctgctct ccggccgagg atcgggtgcc gacctgtcgg
     8581 tgcgcgagat atacatggcc gaatcggtgc gctggcacct ggatcgcgcc gcaccaggaa
     8641 cccgcatggc gctcgtgtcg cacaatgccc acatccagaa gacgcctgcg tcgttcggcg
     8701 gcgccctcac cgcgctgccc atgggccacc acctccagcg gatgctcggc gaggactact
     8761 gctcggtggc cgtcacccac accacggatc atgtgccgga gatgtatccc gatgaaagcg
     8821 ccagagtcgg cttcaccctg gccgacgctc agctggagcc ggctgagttc ggcagcgtcg
     8881 aggccgcgct catcgacgcg ggtctcggtg acgggatcac actgaccgac ctgcgccggt
     8941 cgccgcgcga cgcccatggg gtgccgctgc tcaaccggat ccggagccag agttccagcc
     9001 tgtgcgcccc gatccccgag gcattcgatg ccgtgctcgc cgtcccgaca gttacccggg
     9061 atcgaacggt gcgcttctga ccgttcccgt ctcccattcc gacgtccctg attcccggaa
     9121 ttcctggagt gggctgccgg taaaccatcg aacgggcttt ccgggggttc ccgttcgatg
     9181 gttgcccttc ctttcggcct ggaggccggt cggggatttt ccaggagggc gcgcacggga
     9241 ctgacgccac ctgggcggga gagaatggcc tgagggtcag gggctgggga gttaaggggc
     9301 tggcgtctgt ggcttgtggc ctgaggcgtg tgtcccgcca cttgcgttct gggcgtgaac
     9361 tgtgctgacg ccgtcgggca gttgggcgac cggccgtcct tgctgcgacg ggcgcccggc
     9421 cggttgccct gcctgtgacg tccgggtcgg cacgcacgcg ccgacacatc gttcactcac
     9481 gtggggtagc tcggccccgg gtagggatct tttttccatc ttccgttttg tgggtggcgg
     9541 atacagggag caggttttct tgcgaactcg ctgtattcca ctgggcggtg agtgtgattc
     9601 atgccacaga ggcggtgatc gggccggtgc taggttccgt tgtcagcaag tccgtattgc
     9661 tgatggcaaa aatcggaggt tgcaatgacc gagcagtccg agcagacacc cacggaatac
     9721 attccgccga tgctcgtcga ggtcggcgag ttcaccgaag acacgttggg caactggcac
     9781 ggcacgtcgc ccgactggtt cttcaactac tactggtaaa tcgtcccgcc agtagtaact
     9841 gaccgacggg ggaaccgggc ctgcctgtgc ggagcccggt ctccttctcc attcatgagg
     9901 gctctggcct gccgccgcgt cgaggcactc ggtgcctccc gccggtgcgc gcttcggcca
     9961 ggggaccggc ggggggatgg cgaagttgag tactgggttt gtggtcctgc cggacaccgc
    10021 ggacggcgcg gagatccggg cgctcgtacc gttcgcgcat gcccgagtga tcgcgcacgc
    10081 ctccggacgg ccgtggctgg tcggcgagtg gtcccacggt caggtgaggg tggcctcggc
    10141 gggtccggta cgtctggccg tgagcggcac gtgtccggtc accgacgacg ggctggcacg
    10201 gattgccgcc cgtatctccc ggctgtccga cgtggaccgg gccgttcccg cgctgctggg
    10261 gtcctgccac gtcgtggcat cggtggacgg gcacgtccgg ttccagggca gcgcctccgg
    10321 gctgcgtcgc gtcttccaca cccgggtgaa cggggtgcgg gtcgccgcgg accggtccga
    10381 tgtgctcgcg gcgatgaccg gtgccggggt ggacgaggaa acgctggcgc tgcacgtcgc
    10441 atgcggtttg caggtgccct ttccggccaa cgcgcgcagc gcgtggtcgg gcatcggcac
    10501 gctcgcgccg gagaactgtc tgctgtggga ggacgaccgg gaccgggaag cggtgtggtg
    10561 gcgcccgcct gagccggacc gttcgttgag ggaggggacg gcggccgtac gggacaccct
    10621 gaccgccgtg gtggaccgac gagcgcctgg cgaaggccgg ttgagtgcgg atctgtccgg
    10681 cgggctggat tcgacgtcgc tgtgttttct ggcggcccgg cacaccccgg agctgctgac
    10741 tttccgctgg ggcgaggccg acgcgggcaa tgacgacgcg gtctacgcgg ggcaggcggc
    10801 gcggctgctc gaccgtgccg agcacctcgt cgtgccgcag cacgaactcc ccgacatctt
    10861 cgccgacccc gccatcgcgg tgtccgccga ggagcccctg tcgctgacgc gcgcgacggc
    10921 ccggatccgc cggggcgccc ggctgctcgc ggaccgcggc tcgcgccggc atctggccgg
    10981 gcacggcggc gacgagttgt tctccccgat gccgtcctat ctgcatcagt tgatgcgccg
    11041 tcatccggtg acggcgctca agcacgtacg ggcgcactgc gcgctgaagc gctggccgct
    11101 gagggcgacg ctcggcgagc tcgcgcagcc gggaagtctc cccgcgtggt ggcgggagca
    11161 ggccgggctg ctgaccgagc cccggccgcc gctgcggcgc ccggcgctgg gctggggtct
    11221 ggggcccgta cgtgcggcgc cctggatgac ccccgagggc gtcgagctgg cgcgggaggc
    11281 actgcgccgg accgccgacc aggcgcagcc gctcgccgag gacctcgcca cccacacgat
    11341 ggtgctcatg atccgctcca acacggccag ttaccggttg ctggcgcggc tgtacgccga
    11401 gtccggtgtg gagctggaca tgccgtatct ggacgacacc gtgatcgacg cggtgctccg
    11461 ggtaccggcg cacgagcacg ccggaccgtg gcggtacaag cccctgctgg ccgatgcgat
    11521 gcacggcatc gtgccggacg ggatccgggc gcggaccacc aagggcgagt tcggcgagga
    11581 catcagaagg gggctgcgcc gcaacctgcc cgccatcctg gacctcttcg ccgattccga
    11641 gctggccgcc cgcggcctga tcgacaccgg cgcgctccgg ctgcggctgg gcgggccgca
    11701 gccggacaac accaccgccc aggcgctgga gagcctgctc ggctgcgaga cctggctgcg
    11761 caccacgtcc ggccccggca cccttccccg tgccggcaac ggcaccgtcc cctcggaggt
    11821 ctgatccgta tgcggctcca tcccgacgtc tccatgacgg acaccgacga cggcacggtg
    11881 ctgctgcatc agcgcaccgg ccgctattgg cagctcaacg tcaccggcag ccgcgtactg
    11941 caccgcctgc tggacgggga cacccccgag agcatcgccg acggcctcgc cgccgcgcac
    12001 ggcatcgacc cgcagcgggc ccggcaggat gtcggcgccg tgatcgagca actgcgcacc
    12061 gccgagctga cggtggcctc atgagccagt ccatggcact ggaccagcgg gcccggctcc
    12121 cgctgctgcg ccgcctgctg ccgctgctgg ccgtcggcgc cgcccggccg ctcgcccgcc
    12181 tcaagcccgc gcggctgcgc gccgtgctcg aattcgcccg ccgtggtgcg gcgccggcag
    12241 atgccggaca ggcgcagcgg gcgcgcgacc aggtggtcgc ggtgagcctg cgctgtgcgg
    12301 ggcagaactg tctgcagcgg tcgctcgcca ccgccctgct gtgccgggcc cgcggggtgt
    12361 ggccgacgtg gtgcaccggc gtacggacgc accccttcgc cgcccacgcc tgggtcgagg
    12421 ccgagggccg gctgatcggc gagccgcacc ccgagggcta ttacaagccg ctgctgaccg
    12481 tcccgccccg caccggagcc ggcgccgggg accgctgagc gccggcagcc gccgatgccg
    12541 tcggcggccg cccggacgta cccgttccgt ccgcaacgat cgatcgaagg gctgatctcg
    12601 tgcaccctct ccctctcccc cggcaggagg tggccgcccg atgaccaccg tgcacacgga
    12661 cggagcgccc cgccccgcgg ccggcgccct ccgcctcgtc gagagccgca ccacccgccc
    12721 cacgacggtg gacttcgcgg agtacgtgca ggcgatgtcc gtccactgcc cgtatctcgc
    12781 cccttccgtg gagcacgggc tgacggggtg gacggtgtac gaggcggccg gggaagcgcc
    12841 ggaggtcgag gcggaggtgt tccacgcggg ggtgcgggcc gcggagtggg tccggaccca
    12901 gctgaacggg ccccgcggtg cgctggtctg cgagaacatc gcggtcatcg gcgccggccg
    12961 ggaggtgctg gcgtggccgc actgggccct gaagaacctc tacggccccg tcggggtgat
    13021 gttcgggaag ttcccggtgg gcgatcaggt caccgaccac cgcggccgcc tcgtcccgga
    13081 gccgccggtc tccttcctcg ccgtgcgggt cgccgtacgg gcccgcgatc cactgttcct
    13141 gagccggacg ccggacctcg ccgccctcgt ggcggaagcg gcggacgacg ggcgggacgt
    13201 cttcggggag ctctcgcacg agtggaagga cgtgaagctg tgggcgcagc gccggctgcc
    13261 gcagcggtga tcctcgccgg cgcgctcaga gcgacgaccc cgtcagcagt cccagcgacg
    13321 tgagcacgac gaatacggct ccccaggcca tgccgtggcg tatgcagcgg tacttgaccc
    13381 acaccgtgcg ggacagcgtc acgaactggt tcaggtcccg gtcctccgga tcggtccgtt
    13441 ggacgacggc agccagccgc cggacggagg ccgtgacggt cgcgtccccg aagtagtgcg
    13501 cacgccgccg ctggggcgta ccggggcgtg gtgccacggc cagtccgagc agcacgagag
    13561 ccggcaccca cgccgcgcag ccggtccaga agagcgcctg cggcaccggg gcgtagagct
    13621 gtggggtgat gccgccggcg ctgatcgcgc cgaggagtgc ggtcagcgcg acccccagcg
    13681 cggtcagcat catgcccgcc ttgctgtccg ccttctgtag ttcctcccgg gtctcggtga
    13741 tcaaggtgcg gatgagtgct ccgccgtggc cggccgtcgc gtctcccctg tgggtggtca
    13801 tgcctgctcc ctccgtggga caccgaggag gccgccccgg gcgaggccag ggcggccgta
    13861 ctccttctcc gtactcggtc gcggtcagac tcccgaggtg ttccggagtt cctgctccag
    13921 tccgttcacc gccttacgga gccggatgtt caccgtcgcc acgagctcgc ggtgggccgc
    13981 ctcggactcg gcgcggctgc gccggacctc ctgctcgatg gcttcctggg cgatttcgat
    14041 gtctgccatg gcgcggcgct cggtgagccg cacctgctca ccgtggatct tgacggcgct
    14101 gttgctctcg ctggtgagca tccggtcgta ggcgctctcc ccgctcagga acttcaccag
    14161 caccggaagc gcgtccagga gcacgaagag cgcccggacc agccatatgc cggcgaacag
    14221 caccgtgttc ttgcccgcga ggccgtccag cgcccccatc cgctccagta cgccgatctc
    14281 cttctgcttc gcccgctcct tggcgaggcg ccgctcgatg cccgcggcac gggcctgcag
    14341 gaaggtgccg cgcgaggccg tcaccttgcc ctccatcgcc gcgatgcggc cgtgcatcgc
    14401 ggccagccgc cgctcgttct ccccggtgcg gtgggtgctc cggtagtcct tcgccttctc
    14461 ccgcatccgc aggcactcgg acgtccgcga gtacagcccc gtggaggcga tccggatcag
    14521 ccgccggcac tcgttgcgca cctcgccgtc gagggtgtcc agcgcgtcgt tgtcctggtc
    14581 cacccgcttc tggagggcgc cggactccgc gcgcagggcg gagagttcgt cggactgtcc
    14641 gccgggggtg gccccgaagg acagcacgta ccggccgcac cccgcgggcg acgaggcctc
    14701 ggtcgcggac ggcacggggt tgcagcgcag caggttgccg cgcagctggt cgaggtcggt
    14761 gttccgctcg ccggcgatgc gctcctcgac ggccgtggcg aagatgcgca gcaccagcgg
    14821 ctcggcgacc acggccccga gcaccaacgc gatcagcagg cgcagcagca gcggcccggc
    14881 acgacgccgg gcgttcggct gcggggtgac cagccagcgg tccaggttga ggatgaagag
    14941 catccagatc acggtcggga tcacggccag cagcgacacc ctgcccagtg cctcggtcgc
    15001 gaagttccac atggagaacg ccgcgatgac ggaggtgccg agcaccacgc cgccgagcgc
    15061 ggtgtacctg ctccgttcgt acccgacctt ggcgaggagg tcctcgtcga cgccggtcag
    15121 ggcgcgcagc cgccgtgcgg ggtcgagtcg cgcgaaagcg tcccggtagg gggtcgggga
    15181 gtcagtcaac gagatcgtcc tcgtcctgca cgaagccgtc ctgcgggcgg ccggcgccac
    15241 tgttcagccg ccggggcgcc tcggatccgg ggctctgcgg acccgggccc accgccggga
    15301 cgcccgggcc gccgccgtcc ctcagtacct gttcgagcac ctggtggtag tcgacgtagt
    15361 cctcggccgc ccccatctgc cgcagcaggg tgagcaccat gtcgcgccgc atctgcgctt
    15421 ccgcggtctc gcgggcgcgg gcgtgcgccc ggtcctcgtc ggcggcccgg tggcgccggg
    15481 acgcgtcctc gtccgtggtc cggtggatcc gtgccgcggc ctgggccacg tcgatgcggt
    15541 tcctggcgat cccgaaggcg tccgcgtagt cggacccctg cgagagcagt tcggcgatcc
    15601 gctgggtgtc ctgggtctcg aagtcacgct ggccgcggcg gagttcctgc gagcggcgtt
    15661 cgtcgcgcat tttctgctcc caggtccgca ggtcgtccga ggcgtggacc tcggcactga
    15721 cgaactcgac gctcatcccg gcgacccgcg gcgccacgat cgcgctgtat gcggtcatac
    15781 ggtgactcac ctcgcggcgc accgcgttga cctcttccac gcggtggccg gcgctcaccc
    15841 tcggcagctc gctgtcgccc gccagatagg cccgcagcgg cacggtcaca tcgatgatgc
    15901 cctggcgggc gacgaccgtg gggtcggtga cctggcaggc gaaggaggca cggagcgtga
    15961 agtggtcggc ctcgctcacg gaggggacgg tgcggtcgac ctcgaccatg cgtgccctgg
    16021 tgtccaccag gctgaccgag gacgcgtcga gcacatcggc gtgggagggg tcgaacacca
    16081 tgccctcggg gaactggcgg tagttgccgc cgaccctgaa gacgtagacc gcgccgggcg
    16141 gcagcggggg gacatcatcg cggcgacggc gccgcgacca ccagttgccc tggacggtgc
    16201 ccagcacatg ctcggcgact accgggtagt tcacttgctt cagcctcctt ggagggaagg
    16261 gacagggaca ggtagggagg ggggaggggc tggctcatcg gccgttggcc agggcgtgcg
    16321 gtcggctcgt cggccgtcgg ccaggcccgt cttcgggcac accccctagc ccctcagcga
    16381 ccccaggagc acctgcgcca gccggcgggt gccggggatc gcgtactccg ggtgcctcaa
    16441 ggcgtggggc aggtcgtttc ccagcgcttg ccattgccgg ggggtcatgg cgctgcgcat
    16501 cgcctcgccg agggcccgta cggcagcggc tgccgacggg tcgtcgcgca ggtccgccag
    16561 ggtgcggcac agggcacgga cggccccgcg acggcagacg ctgagcagca cgctgaccca
    16621 cagcaggccc agctggcgcg cgcttcccgg gacgtcgcgc agcagcgccg ccgcaaggac
    16681 accggagccc tccagccgtt ccgcttccag cagttggacg gtcgtgcgca gggccaggga
    16741 gcgggctttg gagcgctgag cggtgtcggc gatccgggtg cgcacatagc ggagggtgaa
    16801 cagggcccgc tcggggtcct gttcggcggt ctgcagcagc aggaccagcg agcggcgggc
    16861 ggcgaacgcc atccgctcgc cccgctgtgt caggaaccag agccagttca gggcttcgag
    16921 ccggtagagc gagccgaggg tgccggtcag ggccatcgcc gtcgtcacgg cacgggccgg
    16981 gcctttccgc tccgcccagc tcagcgccag gttgagcgcc tgcggcgcca ggtgctggtc
    17041 gtcgcacatg aactgcaggg tgagcgcggt ggtcacgcgc tgggcggcca agccgtcggc
    17101 ccatacccgg aggaggttct cgtccacctc ggcgagcgca tgccgtgcgt agagcgcgac
    17161 cccgcgcgcc acctcggtgc gaacgtccag gtccgccagc cgcgacagct cgctcagcca
    17221 ctgccgtacg gggtaccaga gttcataccc atacaggtcg tgcagttcgc cgatgaccag
    17281 cgcccggacg cggggcgagg tgaagacgat gcgccgctcg ctgcggctgg ggtcctgtcc
    17341 cgggccggcc cgccgctccg tccgcacgag cccggtggcc cgctccttcc agcgcgcgcg
    17401 ggtttgctcg aaggtcacgc cgcgcagcgc cgtcgtcccg gtggcctccg gctcggcggc
    17461 aggcgtctcc ccggtctgct cccagtcccg tacgtgcatg ccgagcagga cggacgcctt
    17521 ttcgaagttg cgctccggta tgccctccag gaaggcgagg gccgccagcg gcagcaggtc
    17581 accggcggac ggttcggtgc ggaaccagtt gcggacccgc tcccgctcgc tgtcccgcag
    17641 catcttcagc gcggcgtcgg ggccgtcggc gagtccggtg accgcggcga cgacgtccgc
    17701 cggccgacgc agttcggcca cccgctcctg cagttcctcc gcgacctccg gggggaggcc
    17761 cgcctgcgag gtcaggtgcc ggcagtggtg gaacagctcc agcgggtccg gtgccgccca
    17821 cggcacgcag tggtccttca gggccagccg ccgccgggcg gcctcagggg cggtgatcac
    17881 caggtacgag cccttgcggc gcagctcctc gctcagccgc cggatctcga aggcctgcac
    17941 ggcatcgacg ttcatctcgc cgacgtagtc gaggatcacg tacgcctgac cggccttgag
    18001 ggcgctcgat gcggcaagtt cggccagcga attggcgggg gacaggctcc gcagcccggt
    18061 gtgcaccccc cgcactcgct gaagcagggc gaacgcacct gcgccgcgtc cgctgctgtc
    18121 cggacccgcc aggaccacga ggtgctccgc acggagcgtg ccgagcgcgt cgtcgaagca
    18181 cggccgaggc gacaggtagc accgcagcgc ccggtccacc tcgtcgggct ccacgaagcc
    18241 cggggccaga ccgggggcgg ccgccgcacc gaagccgaac gccgccccgg aagcgtccac
    18301 caccccgtag aagttgttgt agacccgctg gcccaggacc tgccggaggt cgtcgtagcc
    18361 cttgccgtcc tcctcccgct ccttccgctc gtcgcagtcg gcaccggagg caccgccggc
    18421 gtccgtccgg tccgccggag cgtcgtcctc cggctgctcc tggcggagct cgtcctccgg
    18481 gccgggtacg ggaggttcgc tgaggtcggg ggcgccggcg tcgtcagcca cccgcgctcc
    18541 cgaagccgac gacgcctccg cgcaggtcca cgggcgcggt gaagtggttg acgctgatct
    18601 gctcgccccg gtagtcgtgg cgcgccgcgg agccgtcgcc gggcgcaccg tccgtgggcg
    18661 gctgcggccg ctccgcggcc ggcccgtggg cggccgggtg gggcgcctcg tgcccgggga
    18721 cctggagcca cccgacggcc tcgcactcct tctcccgcac ggtgacgcgg cggaagtccg
    18781 cggcggacag ggtggtgtgg ccgcccgcca ccgtggaccg gtagacgtcg tcggagagca
    18841 gcagcgcgag gtcggcgccc tcgttcgtcc ggagggcgtc gtagaggtgg cgggagctga
    18901 gcagccgtgc ggtggtcacc accgtcgatc cggcgaaccc gttgtcggca agctccaccg
    18961 ggccgtggtg gatggcggcc cgcagcctca tccgtgcggt ggggacccgc aggccgttgt
    19021 actcacggag ttcggcgacg agatgacgta cgaagtcgtc gacgaggcgc ggttccgtgc
    19081 cgtccatggg gtggacggcc agttcttcat cccccttggg ctggatgtgc cactgcgaac
    19141 gatccagtcc ggttcctcgg gccgcgcggg aaagaatccg cggcagatcg tgctggattt
    19201 cggactgcct acgatcgttg ttgcctccgt acgcctgcgc gtccacggcg atacatgtgc
    19261 aggggtagaa cccggaccac tcggccaccc agccattcct ctctctgacg gcacttcccg
    19321 cgaagtgccg tcagagaggc taggagcgca cccgagaact gatcccgtat caatatgggt
    19381 tttcctgaaa gactttggcg aacacaagca gcttcgatac gtcacagacg gttatctttc
    19441 gatagctgcg ctccaccagg ccgagcttgg aaagcgaggc aagggccttc tccgtcgtcg
    19501 gcagggccag cccggcgagt gaggcaagtt ccgcctgatt gagggttacg tcgagaattt
    19561 gccgccttgc gctgccgtcc agcacttcgt tcccatacgc ctggctcaat tcggcgagta
    19621 cgcgggcaag ccgggtcagc gagtcgtatg cgcggaaatc catacggcgc cggttcgccc
    19681 acctcagccg cgcgcacagc atggccagca tggcgcgcat cgcgtccgga tggcggccga
    19741 ggaagctctc cagcgcggtc agctggatga tgcgtgcaga catctcgctg cacgcaatca
    19801 cggtgccgga acggggctgg tcctcgaagg ccgccatctc gccgatcaga tcaccgccca
    19861 cgcggatggc gagcagcatc tcgtaaccgc tctccgaact ggcgacgacc ttggccacgc
    19921 cacgggtgag caagaggaca tggcgactct cgtccccctg ctgcagcagc tggcgatggg
    19981 cgggatacac catcggagtt cccagcccca tgagttcttc caaggtgctg ctacgcagcc
    20041 gtccaaggaa agtggaatgc ggccacgcgt gcttcatccg atacccccgc ctgcttcacg
    20101 ctacggcgca tcgcgccttt tcaactggcc cgcccatgct gccgccgggg cacgaaaagg
    20161 caagtgagca ggagtcatct ggctggttac ttccctgagc cgcccagtat tgatcgaacg
    20221 aatgagccct tattcacgaa ggggttccgg acggccgtcg actctccccg ggatcgtcac
    20281 gaatgagacg acggtcggcc ccgtccgtac ggaccaggag acagccgagt ccttgcgcgc
    20341 ggccgcgcca cccccgcagt cgtcctcagc ggccggaggc ggcggccggt ggcggtaccg
    20401 actcgccctc ctcctcgtgt tcgacggctt cgtccaccgc ctcggggggc atggcgaggt
    20461 gcacggcggt gtagtggatg acgaggctga agacgatcac gatgaccagg tcccaccagg
    20521 cggggagggc gcgggtgccg ccgtagcggc cgaagcggcc gatgaggacc atgccgccca
    20581 gccagggcca gacccaggcg gccgatctgc cgcgcaggac gctgcgttcg gccgccggga
    20641 tgccgcggcg ggtgagcgcg aagacgacga agccgagcag ggcggcggtg ccgagtttcc
    20701 agtccgcctc gtaaccggac cagtagaaga tcaagttggc gaagacgaat cctgcggggg
    20761 ccatggccgt cccgcggggc agccggtagg ggcggttgcg gccggcgtcg cgtacgcgca
    20821 gggcgtgcag ggacaccggc gcgaacgcgt acatgatcgc cgctgccgag gtgaccaggc
    20881 cgaccagggc ctgccagctg gggaacggca ggaaggcgag ctcgccgacc acgaacgcga
    20941 ggaggatcga gacgacgggc acgcggctgc ggccgacctg gctgaggggt ctgggcagca
    21001 cccgctcgcg tcccatggcg tacgagagac gggcggcacc ggccatgtag accaggccgg
    21061 tgccggccgg ggagatcacg gcgtcgacgt agaggatggt cgccagccag ccggccccga
    21121 cggcggtggc gagggtggcg taggggccga agttgccctt gcccaccggg ttgtcccagc
    21181 tgtgggtgag ggctgtgggg tccagggcgg cgatgaaggc gacctgcagc aggagataga
    21241 gcgcggtgcc gatcgccatg gccacgatca ccgcccggga gacgtcacgc tggggatcgc
    21301 gcgcctcacc ggccagctgg atggcctgct cgaagcccag cagcgcgaac accactccgg
    21361 caggcagcgc cgcgaaaacg ccgtgcgccc cgtgcggtgc gaagccgccg cccgcggtga
    21421 agttcgatcc gtggaaggcc agcgtcatca gcaccacgac ggtcagcagc ggcaccgccg
    21481 ttttcaccac ggcggtgacc gagttgatcc cggccagcag ccgtacgccg aggacgttga
    21541 tgagcgtgaa gagcagcatg aagaaggtcc cgatgaccag gcccgcggcg gtgagggtgc
    21601 cgttggggtg cagcaggtgc acccggtcgc ggacccagcc gatgcggtcc aggtacgaga
    21661 gggtggcctc gacctcgatc ggcgcgatca ggaccgaccg cagccaggac atccagcccg
    21721 ccgtgaagcc caccaggggg ccgaaggcga agaaggggaa gcgggcggtg ccaccagcga
    21781 tcgggtaggt ggcgcccagc tccgcgtggg ccagcgcgag cacggcgagc atcgccgagg
    21841 cgagcaccca ggagatcagg gaggccgggc cggcgatgac ggcggtggtg agggcgccca
    21901 gcagccagcc ggagccgatg atcgagccca gggagatgaa catcagcccc cagaacccga
    21961 ccgcccggcg gaggtggcgg gttccagcgg cgccggcatt cccggccgcg gccggcctcg
    22021 tcacgcgcgc tcctggttca cgccaccatc ttggggccgg gaggcgggcc tgacgggacc
    22081 gacgcgctgt gtgtcactcc gtgtactgca ggtgaggggg gcgggtgccc tgcacgtggc
    22141 ggcgtacgcg tcgtctgtgg cggcggctgt ctgctggggg cccgcggacg tcaccgcggc
    22201 cggcggtcgc cgtcggcgac cgggcgcacg gggggtgagg tgtggactgc gccgttgtgg
    22261 gacggcgggt gggtgtggaa cagcgtggcg tacaagccgc ggtgggcgag gagttgggcg
    22321 tgggtgccgg actccatcag gcgtccccgg tccaggacca ggatgcggtc ggcgtccgcg
    22381 gcgaggtcca gatcgtgcgt gatcacgatg gtggtgcggc ccgcggcgag gcgccgtagt
    22441 ggcccgagga tgcgttgggt ggccaacgtg tccaggccgg tggtgggctc gtcgaggatg
    22501 agcaccgggg cgtcgcgc
//
