LOCUS       NZ_LT907981            22619 bp    DNA     circular CON 12-FEB-2024
DEFINITION  Streptomyces sp. 2323.1 chromosome I.
ACCESSION   NZ_LT907981
VERSION     NZ_LT907981.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. 2323.1
  ORGANISM  Streptomyces sp. 2323.1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 03:31:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,058
            CDSs (total)                      :: 6,971
            Genes (coding)                    :: 6,808
            CDSs (with protein)               :: 6,808
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 163
            CDSs (without protein)            :: 163
            Pseudo Genes (ambiguous residues) :: 0 of 163
            Pseudo Genes (frameshifted)       :: 64 of 163
            Pseudo Genes (incomplete)         :: 123 of 163
            Pseudo Genes (internal stop)      :: 17 of 163
            Pseudo Genes (multiple problems)  :: 37 of 163
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3637116
            Orig. end                         :: 3659735
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT907981.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22619
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="20"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22619
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22619
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12619](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12619)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(12..26)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.39"
                     /tool="antismash"
     misc_feature    13..24
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.21"
                     /tool="antismash"
     misc_feature    complement(1078..1089)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.88"
                     /tool="antismash"
     misc_feature    complement(1136..1151)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.31"
                     /tool="antismash"
     misc_feature    1671..1688
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            2166..3209
                     /locus_tag="CPH93_RS15275"
                     /old_locus_tag="SAMN06272775_3121"
     CDS             2166..3209
                     /NRPS_PKS="Domain: Abhydrolase_1 (16-266). E-value: 2e-16.
                     Score: 52.3. Matches aSDomain:
                     nrpspksdomains_CPH93_RS15275_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321038.1"
                     /locus_tag="CPH93_RS15275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3121"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_096215450.1"
                     /sec_met_domain="PF00561 (E-value: 1e-10, bitscore: 40.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.1e-09, bitscore:
                     35.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRERDGTPPGHLDERTAVLMLHGRSVPVLAGFDLDFKSYNWADAL
                     AEAGYDVFMMDLQGSGLSPRPKMDDPRNVNPAQQNLLKPRPPGFTPGPPNYPFQLTNSN
                     SDRDELNTVVEWIIRERGVKKVAFIGWSAAAFTMGPYAVKNPGKVSSLFLLAPIFPPEG
                     TSNTPDPLPQPGFPTFLSTKDGTWNGWSNEVHCEGQREEEMRDKVWNAIMKSDPVGSTW
                     GPDDEGRNRIRNFVRWGWNKTTASQGGVLGGSVPVLIAYGEYDRQANTSSEDPEFNFSV
                     RALYNAIAGDHKLMVKLDCAGHSVVWEMQHKNVHNLSKHWLKHLKVDGKTQGIFDMNTN
                     GDISPAP"
     aSDomain        2214..2963
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPH93_RS15275_Abhydrolase_1.1"
                     /evalue="2.00E-16"
                     /label="CPH93_RS15275_Abhydrolase_1.1"
                     /locus_tag="CPH93_RS15275"
                     /protein_end="266"
                     /protein_start="16"
                     /score="52.3"
                     /tool="antismash"
                     /translation="AVLMLHGRSVPVLAGFDLDFKSYNWADALAEAGYDVFMMDLQGSG
                     LSPRPKMDDPRNVNPAQQNLLKPRPPGFTPGPPNYPFQLTNSNSDRDELNTVVEWIIRE
                     RGVKKVAFIGWSAAAFTMGPYAVKNPGKVSSLFLLAPIFPPEGTSNTPDPLPQPGFPTF
                     LSTKDGTWNGWSNEVHCEGQREEEMRDKVWNAIMKSDPVGSTWGPDDEGRNRIRNFVRW
                     GWNKTTASQGGVLGGSVPVLIAYGEYDR"
     gene            complement(3534..4345)
                     /locus_tag="CPH93_RS15280"
                     /old_locus_tag="SAMN06272775_3123"
     CDS             complement(join(3534..3994,3994..4345))
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012606213.1"
                     /locus_tag="CPH93_RS15280"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="SAMN06272775_3123"
                     /product="IS5 family transposase"
                     /protein_id="WP_231977348.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MGTSPWIVSDELWDRLEPLLPQRERRFRYPGRRALPDREVLCGIL
                     YVLHTGIQWEYLPQELGFGSGMTCWRRLRDWNEAGVWQGLHEVLLAELNAASRLDWSRC
                     VVDSSHVRALKGGKRTGPSPVDRGRAGSKHHLITDGHGTPLAVLLTGGNRNGVTQLLPP
                     LDAIPPVRGRVGRPRRKPDSLFADRGYDHDMYRDQVRARGIVSAIARRGTRHGTGLGTY
                     RWVVERSFAWLHGFRRLRIRWERRADIHEAFLKLACCLITHRQLRSLC"
     misc_feature    complement(4004..4006)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    4422..4437
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.74"
                     /tool="antismash"
     gene            complement(4463..>4914)
                     /locus_tag="CPH93_RS15285"
                     /old_locus_tag="SAMN06272775_3124"
                     /pseudo=""
     CDS             complement(4463..>4914)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268836.1"
                     /locus_tag="CPH93_RS15285"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="SAMN06272775_3124"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="QGTDAGKRIIGRKRHLGTDTLGLLLTVMVTAASVSDTAAGVHLLA
                     RIAAAHPQVRKAWVDAGYRTTAIDHGARLGIDVHPIQRPPGTRGSQ"
     gene            complement(4975..5154)
                     /locus_tag="CPH93_RS15290"
     CDS             complement(4975..5154)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014053989.1"
                     /locus_tag="CPH93_RS15290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_231977436.1"
                     /transl_table=11
                     /translation="MTEVATVMRVSRMTVYRLVHSGALPAIRVGRSFRMPEQAVHDYLK
                     ASFKGSLSGVSPRL"
     gene            complement(5429..6271)
                     /locus_tag="CPH93_RS15295"
                     /old_locus_tag="SAMN06272775_3126"
     CDS             complement(5429..6271)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014668656.1"
                     /locus_tag="CPH93_RS15295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3126"
                     /product="hypothetical protein"
                     /protein_id="WP_096213167.1"
                     /transl_table=11
                     /translation="MGGDDELVDEESTAVRSSDLQPVEDGPILADPVSTRELSALEAPT
                     HSGTTQHLQATIDQHMADARLVNVLAEDGFAGPRYERFEEELARYGISVMRGWMYSGFV
                     FKLVASRGFNLLPHDVELEQLARDSDLREELAMMTVARALRRFRERALVGGGWKPAGGA
                     SITTYFMGACAYEFPNEFRRHRKEEERWRRGTEQEATGEPVPSVQSVAEEVLGNLRVLE
                     DINGIENPRARAVVALTIDGYTQEEIRQMLDAPTVRAVEAVLHRWRAKAKRELEGRHG"
     gene            6506..6667
                     /locus_tag="CPH93_RS36160"
     CDS             6506..6667
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014668657.1"
                     /locus_tag="CPH93_RS36160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_173909818.1"
                     /transl_table=11
                     /translation="MTMHTAIILLAAVIIGLIAGILTFLSGTLVPAAVLAGLSASGLSI
                     PVLRSLIG"
     gene            6809..7087
                     /locus_tag="CPH93_RS15305"
                     /old_locus_tag="SAMN06272775_3128"
     CDS             6809..7087
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CPH93_RS15305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN06272775_3128"
                     /product="hypothetical protein"
                     /protein_id="WP_096213169.1"
                     /transl_table=11
                     /translation="MPRPRDPGDLSSPAPTTDRELALAELLIDEMAGVDIGELHDGYAQ
                     ALNVLVDTQAAGGKVLPPREPQQPVGLMAALEASARDARRACAEHRS"
     misc_feature    complement(7269..7284)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     misc_feature    complement(7269..7286)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.39"
                     /tool="antismash"
     gene            7402..8220
                     /locus_tag="CPH93_RS15310"
                     /old_locus_tag="SAMN06272775_3129"
     CDS             7402..8220
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024098.4"
                     /locus_tag="CPH93_RS15310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3129"
                     /product="DUF3800 domain-containing protein"
                     /protein_id="WP_096213170.1"
                     /transl_table=11
                     /translation="MAAFHVPVHFGQLPKLHVYVDETGDRGFSARSQAQSPFFAMTALA
                     LPQEDEWMVTCAAGGLRALVHSGQPQQLLKPIHWVEHFKAKNPQRRSQAAHALASIPTA
                     RVIHVIAHKETLHQDAELRRDKGVFYNYTTRLLLERVAYLAREWPGGKRLAIVRLGQVK
                     HMDHRDCASYLDRVRSGETFGVPWQHIKWPPTWVNTACNGIQLADVHAGLLNSALSGNP
                     QDTACAENLQKISHQLRRSARGDLDGYGIKVIGDKRFVTERAWWPDLKNR"
     misc_feature    7531..7533
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8982..10004)
                     /locus_tag="CPH93_RS15320"
                     /old_locus_tag="SAMN06272775_3131"
     CDS             complement(8982..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013315.4"
                     /locus_tag="CPH93_RS15320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3131"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_096213171.1"
                     /sec_met_domain="PCMT (E-value: 1.5e-24, bitscore: 85.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVADVAQTVPERHYTHHEGRGATANRSNPKAIHRELTTLEVQS
                     AMNVVEFGTGSGYSGALLAQLVGPTGTVTSLDIDNYLVKWANLIHHERGIGNVRCHIAD
                     GTAGFSERAPYDRLVAWCTPPLLPKAWVDQVIDGGLIVAPLPIAAVPNMTVVAKIRIHG
                     GEPVVEQVVNGGYIEATASPKTDLDLPGRWVDWENRVPAPSWISIAWREQDDRLHTGAR
                     TALGRLLKDAHTEPYSGEEVDWPSWRTYAASPADPHLTMAGINPGLWAIGHSTPTTVAV
                     LQQDGTIVADGPDSSSLSVLRDWLSAWEDADRPAPETYTPSLASHDEPGLTGWNLRLTL
                     "
     gene            complement(10001..10504)
                     /locus_tag="CPH93_RS15325"
                     /old_locus_tag="SAMN06272775_3132"
     CDS             complement(10001..10504)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="CPH93_RS15325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3132"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_231977349.1"
                     /sec_met_domain="PF13471 (E-value: 1.7e-12, bitscore: 46.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSMEAYSTVRTGTYLERLAAAAGLTLALVLLRLPFRHTVRATRL
                     ATQAGRRLLAPARAEALVGAVRHTARWWPGRAACMETSLGAVLAAALLGRRLTWCIGAR
                     FSPPPVEHHAWAELPDHGPVGEYTVAGWHYLTGMTIPGRRARIHQPPQAVVAYECPTPR
                     RSEQ"
     gene            complement(10501..10794)
                     /locus_tag="CPH93_RS15330"
                     /old_locus_tag="SAMN06272775_3133"
     CDS             complement(10501..10794)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="CPH93_RS15330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3133"
                     /product="PqqD family peptide modification chaperone"
                     /protein_id="WP_096213172.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5e-11,
                     bitscore: 41.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.5e-06, bitscore: 27.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWQLRERAHPILTDQGGAILDEHTGRWTQLTPTAAAAVMLLLSCQ
                     TEQQAAHRFAQRYGIGAEQAATDIRTVANRLSAKGLAQAEEAPPRRRRWRWR"
     aSDomain        complement(10546..10788)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CPH93_RS15330_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.00E-13"
                     /identifier="RREFam002.1"
                     /label="CPH93_RS15330"
                     /locus_tag="CPH93_RS15330"
                     /protein_end="83"
                     /protein_start="2"
                     /score="41.1"
                     /tool="antismash"
                     /translation="QLRERAHPILTDQGGAILDEHTGRWTQLTPTAAAAVMLLLSCQTE
                     QQAAHRFAQRYGIGAEQAATDIRTVANRLSAKGLAQ"
     gene            complement(10778..12619)
                     /locus_tag="CPH93_RS15335"
                     /old_locus_tag="SAMN06272775_3134"
     CDS             complement(10778..12619)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033561.1"
                     /locus_tag="CPH93_RS15335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3134"
                     /product="albusnodin/ikarugamycin family macrolactam
                     cyclase"
                     /protein_id="WP_096213173.1"
                     /sec_met_domain="Asn_synthase (E-value: 3.9e-26, bitscore:
                     91.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMRWSAGWYGSAGNDRRPARGRAVPGLESTWTTGWPKAQVRSVGQ
                     GPMALTVIGECGADDRQLESALPVVQARKWRALTRWPGSHLVVARSGETLAVIGDLAGQ
                     HPVYYRTDAAGTWWSTAASALAALDGAPVDVNALAAHLAFSQPDVFADRSLFRSVRRVP
                     GGHLLMIGPDGAMVERYESAAYPPVPLRQAAPTVRAALAEAVAARIDDRPVSADLAGLD
                     STTLACLAAQHAPVTAVTYADERLRDDDLAYAHRTAAAVPGLVHQTVPGNAEAVYYAGL
                     GDLTALPVTDAPNAYVVTASIKRAVLETVAEQASTPGVHFTGAAGDAVLSAPSSYLADL
                     LRERQHRRALCHAVVHARLRHTSAFTVLARVKDAARTDLAGAWMRTAAELRRPARDWIP
                     QAQRPIAWTPLLASADWMAPDVRRRLATALDQAAEELTDAPARLADWSDRQDLARVGTN
                     TAGWRALALAEHGIELAAPYLDNEVIRACLAVPADRRGEPAQYKPLLAAAFTKTGVLPD
                     FVLARTTKGGFNALAYAGLRDHARVLKDLLGPSSRLAALGLVTEYPVAAALARAAAGQS
                     TAQGALHLVVTAEVWLRQLAFAPKHWWEEVKPRVAAA"
     gene            complement(12783..12902)
                     /locus_tag="CPH93_RS35415"
                     /old_locus_tag="SAMN06272775_3135"
     CDS             complement(12783..12902)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CPH93_RS35415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN06272775_3135"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_107470880.1"
                     /transl_table=11
                     /translation="MEHPTEVYEAPVVLDAGDVVTVTLGTQPFDTADDTEYKH"
     gene            13049..14323
                     /locus_tag="CPH93_RS15340"
                     /old_locus_tag="SAMN06272775_3136"
     CDS             13049..14323
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009068302.1"
                     /locus_tag="CPH93_RS15340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3136"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_231977350.1"
                     /transl_table=11
                     /translation="MTIGERIRAAREARRPRCSQQRLADELSAARWGKPGFLDRQQVYR
                     WETERRVPKEWLQFIEQVLHLDLSEDNETQLADTVTSVMLLGGTDVDRRQFLAASAAVG
                     LAAIDLPDAEAVTRRANRPGPVAVGMGEVAAVRTMTTTLGDAASELGGGHARHLAVRYL
                     TLDVRRWLDGRYTEKVGRELFAATSELVHLIGWMARDEGSQGLSQQYNVHSFKLAAEAG
                     ENELAATALRGMADQAIDLGHVATAVRLAEACEQRGRKLKNPKALAYYRNTLARAAAAD
                     GDRTTAGRLLTSSQAAIEHAPPRPGQSWASHYSHGRWAHESGMIHAKLGDYAAAEEHLQ
                     LAMEIHGLDRKRTRAIVLADLGQVQLKRGNISQALATWSDFLTCADGVQSVRINDGLTN
                     IAARLPGIPDSPAVQELAERIATRA"
     gene            complement(14514..15086)
                     /locus_tag="CPH93_RS15345"
                     /old_locus_tag="SAMN06272775_3137"
     CDS             complement(14514..15086)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005475962.1"
                     /locus_tag="CPH93_RS15345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3137"
                     /product="DUF6262 family protein"
                     /protein_id="WP_096213175.1"
                     /transl_table=11
                     /translation="MTERRIPAEVLREARRKDSTRKRERVLSVVDQMLSEGDPVTFASV
                     ARTAGVSNWLVYAEGVREHIEKARAQQAHKAVQDRQAGVTASTASLQTDLELARAEIRR
                     LREERDKLKAAMQRGLGRQLNQATNAELVARIEELTQIAQRLTAERDSLRGEKAGLEKS
                     VEVANDDLAAARTALRNMMRDQNRPIG"
     gene            complement(15083..17590)
                     /locus_tag="CPH93_RS15350"
                     /old_locus_tag="SAMN06272775_3138"
     CDS             complement(15083..17590)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /locus_tag="CPH93_RS15350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3138"
                     /product="site-specific integrase"
                     /protein_id="WP_159395001.1"
                     /transl_table=11
                     /translation="MSEIAVSAGDSRVVQAPFQVDLEAWKLWLTERVADEWRPHEWNPK
                     TWLFNGDPGSVHTAMWKCATVKCELGVHSKDGLCKQCATALKASGMAKPEFTASYVPRL
                     QKSPGIRERCLVTGDQGACQRDSSSLGMCPPHWAAWRRHKEGEDAVSLEVWARTMAVPR
                     PAFPLCLVAGCTLQRTRMSELLCAHHRERYRRHCKGATAPVTLQKWAEWETPWLTQFDF
                     SLAPLAPLVRLEALYAIRERDRHRTRLDPKAVRKAVRRWAGLDSLALSPLPRIQSPDTN
                     EEFFIAESETWLRAGFDKFRGVDPSHDGELNLLTAGLASSHSKSGRRTRGGVVSLAGLQ
                     QPWLRTLLLSWVRMTSPDSLDLRRTLLSCEFASAGLALRSGGGTDVTQLGTLDMDSVIA
                     AFVDAQMKNGTVYSYKSRAEMRRGFLDLLSFGRSEGLLDDLNPRFAAHSGHRIPFVVEE
                     EEDEAGKAIPEPVIRQLDANLGELGRGINCGGLAPGDVMLMMQTAYIICRDTGRRPREF
                     CGLALDCLKYEKGEYNLRWDNKKGKRLRRLLPIEERTAQAILTWKKRRVKLDVPPSNAR
                     YLFPVMNEETKLGHMKSGEFSNAMRAWVDAIPAIDSDAPGDDGKPLPFDREKIYPYAFR
                     SSYAQRHADVGTPIDVLMSLMDHKSAQTTMGYYRVTIKRKREAVETLRGHTVDRSGRPA
                     PLSSGISYEKKSVAVPFGGCVEPSNVTAGGKKCPIRFQCAGCGFYRPDPSYLPAIEDHV
                     RSLKADREMATAMGTDDFVVRNLTDQIEAFQGVVERMNERMAQYPPEVQAEIQEASKVL
                     RKVRAGEGRKLLPLTVVNKAEAG"
     misc_feature    complement(15503..15505)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16919..16921)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17583..18689)
                     /locus_tag="CPH93_RS15355"
                     /old_locus_tag="SAMN06272775_3139"
     CDS             complement(17583..18689)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005475968.1"
                     /locus_tag="CPH93_RS15355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3139"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_096213177.1"
                     /transl_table=11
                     /translation="MSWVVVDAVTYDLHAEGTAFLFQLRSRGLSVNTERTYGGRVALYL
                     SHCAANGVGWANPTLNQLARFLHWLVDEPLPPRGRKTPLEPRFRSKATANAVLTTVCEF
                     LRFGARCGWVRDEVVSRLSSEKYLSHLPAGYDAGEDGQFRTVRAREIKFKVEDEGIEWL
                     TPDQVEEVIGATTRHRDRFLVSLLWVTGVRIGEALGLRREDMHFLSNSRSLGCNVEGPH
                     LHVRRRLNTNGALAKSPRSRSIPVTEGLVELYTEYLHERVAVREAAESDMVFVNLFRGP
                     LGRPMTYAGAKDLFDRLLKRVGFTVRPHMMRHSAATAWIREGQPRDVVQDLLGHQSPSS
                     LDVYVHASDTDKRAAVERVAAARETAHE"
     misc_feature    complement(19163..19172)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(19193..20002)
                     /locus_tag="CPH93_RS36795"
                     /old_locus_tag="SAMN06272775_3140"
     CDS             complement(19193..20002)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089979.1"
                     /locus_tag="CPH93_RS36795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3140"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_173909984.1"
                     /transl_table=11
                     /translation="MAVAAMTAMLCAVALLREVRSGRVVRRRVSTVWAAARPDRYGGHA
                     ARPRASAGVPWRRRATRTKDAAYGRLSEWAGPVGAALFMVILVGGVGGVLAGLAVGLGA
                     HRCLAHQRGAEAARLAAAEVRAALAPAGDLLAACLAAGAGPREAAEAVGRSLDGPVAER
                     LRQVAAELRLGGEPAAVWPRLAELPGAEGLARCMERAGISGVPAVESASRAAAGLRAEQ
                     ARAAVARGRRAGVLVTMPLSACFLPAFLALGVAPVLIGLASGLLGRN"
     gene            complement(20029..20943)
                     /locus_tag="CPH93_RS15370"
                     /old_locus_tag="SAMN06272775_3141"
     CDS             complement(20029..20943)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604149.1"
                     /locus_tag="CPH93_RS15370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3141"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_096215453.1"
                     /transl_table=11
                     /translation="MAAVVCAGAAGRLAGGRPDDVRRRARALFGSHGERDAEAGWRARM
                     RAQKVRKWCLQRVVEGDAGRRWRVGPLGDVGWELWCLPAGLVLGVLGGSALPPLASVAA
                     AFLVRRWLIARGAVRARDRRAAAVITLCAAVAGELRAGRQPAQALLAAGTPGLGAAGSA
                     VTAAARYGGDVPQALRATARLPGAEGLTGMAACWQVAVEGGAGLASGLERVAAGLSAQR
                     DQRDELRAQLAGPRATALMLALLPGGGLLMGSALGADPLRVLLHTPAGWGCLVIGGFLE
                     WGGVAWTARIVAAAEGARERGLR"
     gene            complement(20967..22133)
                     /locus_tag="CPH93_RS15375"
                     /old_locus_tag="SAMN06272775_3142"
     CDS             complement(20967..22133)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604150.1"
                     /locus_tag="CPH93_RS15375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_3142"
                     /product="TadA family conjugal transfer-associated ATPase"
                     /protein_id="WP_096213179.1"
                     /transl_table=11
                     /translation="MSQGQDLLEAVRRRLAEDGADPTPARVALALREQGRLLGDAEVLG
                     VVAGLRSEMVGSGPLEPLLAAPDVTDVLVTAPDEVWVDRGGGLERTEVRFRDAAEVRRL
                     AQRLAAVAGRRLDDARPWVDARLPDGTRLHAVLPPVAVAGTCLSLRVLRPRAFGLAELV
                     AAGTVPPGGDQLLRALLTARLSFLISGGTGAGKTTLLSTLLGLVGPDERIVLAEDSAEL
                     RPDHPHVVRLETRQANQEGVGRVTLRDLVRQALRMRPDRLVVGEVRGPEVTDLLAALNT
                     GHEGGCGTVHANAASDVPARLEALGSTAGLDRAALHSQLAAAVSVVLHLVRDRNGRRRI
                     AEVHVLERDRDGFVVTVPAAVQSPAGFQEAPGWGRLMRLCERGGGGFR"
ORIGIN
        1 atcactgacc acgaaaacgt catccatgct gtggcgcgga tggattacac accgccacct
       61 cccgaacagg gatacaagct gaaagaggcg cgacttgtct ccgtggcgcc gggaagggcg
      121 ttcatcgacc atctgatcct acccaaccag gagcatacgg gcttcgccgt cttctcgaaa
      181 ttcttctatt cgggcgacct cactccgatc tccctgacct tcgacctcac gtgggatccc
      241 ccagcgacaa acgaggctca cgatcgctac gcggaggaga agaagatcta cgacgcagaa
      301 gtggcccagc tgcagcgtgc cgcctacgcc tccgccgtgc gtgagcggct tgaattggtc
      361 agtgcaatgc gcccgcggcc gtcacaagat ctgcgcaacg aggaacgcca aacgatctac
      421 ggaaacgtga tccacaagct caagccattc gagctcttcg aggacaagca tttgggctca
      481 gagctgcttc gacagatctt cgatgtggac gagatgctgt acttcgtggc gccagactac
      541 tggaggcctc acccagtccc cggcgcccca ctccctcctc cggacccttc cgaacccacc
      601 aaagacagca tcggtagata cccggtgccg gatccgagtg ttcttggaga tcggaccgtg
      661 gccagctggt acagccacac cgataagacg aacgcaattg atccgctagg ccaaacgagc
      721 gaagagtggc gcgtgaacta tctgatcacc gagcaagccc aacctgcccc tctaggcagt
      781 tcactgggct ggctgatcga gatcgacggt gacgcacgcc gcaatgagtt cctcaacgca
      841 gcgtgggcaa aggcagtcct gccggtgcgt cccggacacg aggccgaagc gctcagttgg
      901 ctcagagaag cgcacgtcga aggagaagca gcgctcgacc ttccctacaa attccaggag
      961 ggtgaccccg acaactacca cggcaaaaac gtagggcagg tcctggaaga tctcgctgct
     1021 cagttgcaga aatccaacac ggccatcgct aacaccgtcg ctacggaaga ggtcttcgaa
     1081 accggtttcg atcctctgga gggcggtttc aagccggcca atccctatga ggtattcgac
     1141 cagtgggtcg aagtgctgcc cactgatcag gtggtggccg tgcaagtggc ctacgactct
     1201 aagaccgggc agcagattcc agtgcctgtc tccaccgaac ccctcaacgc gggatgaggt
     1261 cgttgtcggc aacggtccga cggcatgcgg cagcccagtt tatgctgcgc gatgaggccg
     1321 cgccgatggg gtgggcgccg ctgcggttct cccgggcgga tgggtatcag ttcacgtcgg
     1381 atctggatga gttgcaggag tacgaggtgc gggtggtgca ccgcgcgcat tgtgctcggg
     1441 tgcgggaacc gttcagacag acctggagca tgtccctatg gttgcaggct gctgtgacac
     1501 cggggagtcc gatgtggtgg cgcggagccc ggctcggtta agggccgggg gagtcctctt
     1561 ttgccggccg ggctccgtgc gcgcttaggg ctcgcagaag aacaacacgc gggcgaacgg
     1621 ctcgctgact tgcgaagtca agtctctgaa cccacaagtt aattgcctgc gagcccttac
     1681 agcggctaac acaatgaggc gcgtcctacc ggtctggtct cttcgcctgc cggtctggcg
     1741 ttcgtagggc agccgcatcg gcgctcgcct ccaggccgct gctcatcgcc cgcaacgggc
     1801 ggcggatgga cgcggagaac acgccgaggc ggatcgtgcg agaggtcgct gagcggcacg
     1861 ccgggctggc ggggctggcg gggctggcgg gcgagctgac cgccgacggg gtggcgctgt
     1921 cgctgtcgcc gttggaggac gacgagcagg agcaggccgc cgtcggcacg gagaaagtac
     1981 acgtcacacg actggccccc tgctgtggcg cggacggtcc cgcgcatcga gcgtggtctg
     2041 ggcggggcaa cgacgccccg gccgagctca tagaacggat cctcatgccc gtcaccgtgc
     2101 aagaccaccg ggtaccccac aagtccaccg tctttgcgaa tcagggcaag gacgtcgaac
     2161 tcttcgtgcg ggagcgcgac ggcacgcccc ccggccacct cgacgagcgc acggccgtcc
     2221 tgatgctcca cggccggagc gttccggtgc tcgcgggctt tgatctcgat ttcaagtcgt
     2281 acaactgggc cgatgcgctg gcggaggccg gttacgacgt cttcatgatg gacctccagg
     2341 gctcggggct gtcgccgcgg ccgaagatgg acgaccctcg caacgtcaat cccgcccagc
     2401 agaaccttct gaagccgaga cctccaggtt tcacgccggg cccgccgaac tatccgttcc
     2461 agctgaccaa ctcgaacagc gaccgggacg agctgaacac cgtcgtggag tggatcatcc
     2521 gcgagcgcgg ggtgaagaag gtcgccttca tcggctggtc cgcggccgcg ttcacgatgg
     2581 ggccgtacgc ggtcaagaac ccgggcaagg tgtcgagcct gttcctgctg gcgccgatct
     2641 tcccgcccga gggcacgtcg aacacccccg acccgctgcc gcagcccggc ttcccgacgt
     2701 tcctgagcac gaaagacgga acctggaacg ggtggagcaa cgaggtgcac tgcgagggac
     2761 agcgcgaaga agagatgcgc gacaaggtgt ggaacgcgat catgaaaagc gatccggtgg
     2821 gcagcacgtg ggggccggac gatgaagggc gcaatcgcat cagaaacttc gtccggtggg
     2881 gctggaacaa gaccaccgcg tctcagggcg gcgtcctcgg cggcagcgtg ccggtcctca
     2941 tcgcgtacgg ggagtacgac aggcaggcga acacgtcgag cgaagatccg gaattcaact
     3001 tctcggtccg cgcgctctac aacgccatcg ccggcgacca caagctgatg gtcaagctgg
     3061 actgcgccgg gcattcggtg gtgtgggaga tgcagcacaa gaacgtgcac aacctctcga
     3121 agcactggct caagcacctg aaggtcgacg gcaagaccca gggcatcttc gacatgaaca
     3181 ccaacggcga catcagcccg gctccgtaga acagccgagc cctcgaccgc gaaccgtggg
     3241 ggcccagggt ccatacgtca gccttgcgcc gtcgccaggg ccgccacagg gtggagtccg
     3301 ccgtctgcgc gccctcgccc gaacggcggg ccacggcatc gtccgcggcg gcgccggcgc
     3361 cctgggcgcg agcgtggccg ggtggatcat ctggtggatc cagcaacgct gacccggcgc
     3421 tgatcccgtc gtccacctgg atctggtggt cccggtcgtc caagaccgga agccggatca
     3481 tggcacgcgc ctcagacgtc aaggcgacgg ccaccagctg ttgcttccca ggatcaacac
     3541 agtgacctga gttgtcgatg ggtgatgagg cagcaggcga gtttgagaaa tgcctcgtgg
     3601 atgtcggctc tgcgttccca gcggatgcgc aggcggcgga agccgtgcag ccacgcaaaa
     3661 ctccgctcga ccacccagcg gtaagtgccc agtccggtgc cgtgccgggt gccgcggcgg
     3721 gcgatggccg acacgatgcc tcgggcgcgg acctggtcgc ggtacatgtc gtggtcgtag
     3781 ccgcggtccg cgaagagcga gtcaggcttg cggcggggac ggccaacccg gccgcggacc
     3841 ggtgggatcg cgtcgagcgg gggaagcagc tgagtgacgc cgttgcggtt gccacctgtc
     3901 agcaggaccg cgagcggggt gccgtggccg tcggtgatga gatggtgttt cgagccggcc
     3961 cgaccccggt cgaccggcga cgggcccgtg cgctgccccc ttttaacgcc ctgacgtgag
     4021 aggagtcgac cacgcagcgg gaccagtcca gccgcgaggc cgcattcagc tcggccagca
     4081 ggacctcgtg caacccctgc cagacgccgg cctcgttcca gtcccgcaac cggcgccagc
     4141 acgtcatgcc cgagccgaac cccaactcct gcggcaggta ctcccactgg attccggtgt
     4201 gtagcacgta caagatcccg cacagcacct cccggtccgg caatgccctg cggcccgggt
     4261 agcggaacct gcgctcacgc tgcggcagca acggctccaa gcggtcccac agctcatccg
     4321 acacgatcca aggcgacgtc cccacaccag accgaacgct caactcccgc cccggacacg
     4381 gcaaccagga ccgatccatc tcattgtgtt agccgctgtt actgagcgtt tggtccgctg
     4441 gttcgtgttt ggttccggca gatcaggtgc cgcgccagtt cggggtggtt tcgccggtga
     4501 ggcggcgggt catgaggtcg atcatggcga gatggatcat ggcttcggag cggtgcgggt
     4561 gggtctcata gtcacgggcg aggcggcggt ggtgcatgaa ccagccgaaa gtgcgctcga
     4621 tcgtccagcg ccgcgggatc actgtgaccc gcgggtaccc gggggtcgtt ggatgggatg
     4681 gacgtcgatg ccgaggcggg ctccgtggtc gatggcggtg gtgcggtagc cggcgtccac
     4741 ccatgccttg cggacctgcg ggtgggctgc ggcgatgcgg gcgagcaggt ggacgccggc
     4801 cgcggtgtcg gagacgcttg cggcggtgac catgacggtc agcagcaggc cgagggtgtc
     4861 cgtgcccagg tggcgcttgc ggccgatgat gcgcttgccc gcgtccgtcc cctgatcagg
     4921 cccccgcagg tcagcgcccc ttctcgcgtg accgagtctt cggcatggct atttttacaa
     4981 gcgaggagag acgccggaga gagatccttt gaaggaagcc ttcaggtagt cgtggacggc
     5041 ctgttcgggc atgcggaacg aacgtccaac ccggatcgcc ggcagtgcac ctgagtgcac
     5101 cagccggtag accgtcatcc tggagacgcg catcaccgtg gcaacctctg tcacagtgag
     5161 gaagacgacg cccttaccag ttgagtgctc gggaggagct gggggttcct cttcggtctg
     5221 ggcctcggcg gccaccccca tgagggcgcg aagatactca attgtcggtg atggcgcgga
     5281 ggcagcggtg tgggggcaat cctgcggttg cgccagttcg cgagtggcag cggcttcggc
     5341 gggagaggtc cgtgcccgca gtaggcgcgc tccggaagag ccgagcgacg actgctccag
     5401 gatggcctcg aaagcttcgt ctcgctgatc acccatgcct tccctccagt tccctcttcg
     5461 ccttcgctcg ccaccggtga agcacggcct caacagcgcg cacagttggc gcatccagca
     5521 tctgtcggat ctcttcctgg gtgtagccgt cgatggtcag ggcgaccacg gcccgtgcac
     5581 gtggattctc gatgccattg atgtcttcca ggacgcgcag attgccgagc acctcctcgg
     5641 cgacgctctg cacagacggc acgggctctc ccgtcgcttc ctgctccgtc ccgcggcgcc
     5701 agcgttcctc ttccttgcgg tgccggcgga actcgttggg gaactcgtag gcgcacgcgc
     5761 ccatgaagta cgtggtgatg ctggcgccgc ccgcgggctt ccagcctccg ccgacgagtg
     5821 cgcgctcgcg gaagcggcga agggcccgag ccacggtcat catggccagc tcttcacgca
     5881 ggtcactgtc gcgagccagc tgctccagtt ctacatcgtg gggcaagagg ttgaagccgc
     5941 gtgatgccac gagcttgaac acgaagccgg agtacatcca gccccgcatc accgagatcc
     6001 cgtaccgggc gagctcttcc tcgaaccgct cgtagcgcgg acccgcgaac ccatcctcgg
     6061 caaggacgtt caccaaccgc gcgtcagcca tgtgctggtc gatggtggcc tgcaggtgct
     6121 gggtggtgcc gctgtgcgtc ggcgcttcca aggcgctgag ctctctcgtc gacactggat
     6181 cggcgaggat tggaccgtct tctacaggtt gtaggtccga ggagcgcacg gccgtggact
     6241 cctcgtccac gagctcgtcg tcgcccccca tgctgctccc ccttcggttc gattgtgatc
     6301 tgccggcttc taagtgccgt ccagccggcc accccacgca ggtcccccaa gtttttctag
     6361 agacgaggtc cacagccaga tgtccgtggg gaatcgcggc cacggcgacg taggagcgtg
     6421 cgtcacaacc accaactact tggaggtcaa gttgagttca tcctccgcgg cgccgcagcc
     6481 caaccgcccc gatcccgccc ccttcatgac gatgcacacc gccatcatcc tcttggcggc
     6541 cgtcatcatc gggctgatcg caggaatcct caccttcctc agcggcacgc tcgttccggc
     6601 cgctgtcctt gccggcctca gcgcatcagg gctcagcatc cccgtgcttc gcagcctcat
     6661 aggctgaccg accggcccat ggacaaccgc ggcgagccgg agccccgacc gctccggctg
     6721 ccggctggca catggcgcct ctgatctcgc cccagcgccg gcggtgtggc ggggccagcg
     6781 gagcctggcc aaagccgggc gagcagcgtt gccacgcccc cgggacccgg gcgacctgtc
     6841 cagcccggcg ccgaccaccg accgggagct ggccctcgcc gagctgctga tagacgagat
     6901 ggccggcgtc gacatcggcg agctccacga cggctacgcc caggcgctga acgtcctggt
     6961 cgacacccag gcagccggcg gcaaggtgct gccaccgcgc gagccgcagc agccggtggg
     7021 cctgatggcc gcgctggagg cttccgcccg cgacgcccgt cgtgcctgtg ctgagcaccg
     7081 gagttgacgg cccggacgaa gatttcggct gagcggggtc cgagttgggc ggtgacatcg
     7141 actggacggc ctgactcgtg cgaagagacg acttgatcca agtcagcagg tcaactgggc
     7201 ttgtacatat gcattgctga catgtcgacc aacgggtgta cggtcatcaa atcggacggt
     7261 agctgggagt gaccggtcgg taacaacgta gagctacccg gcgttggatc gttgggcagg
     7321 acaaaggaga cccgctcccg tggtgcactc tcaccgtggc gcgatgccgt gcccggtcta
     7381 tgcccgcccc aggcgggcct gatggcggct ttccacgtcc ccgtccactt cggccagctg
     7441 ccgaagctcc acgtctacgt cgacgagacc ggcgaccgcg gcttcagcgc ccggtcccag
     7501 gcgcagtcgc cgttctttgc catgacggcc ttagcgttgc cccaggaaga cgaatggatg
     7561 gtcacgtgcg ccgcgggcgg cctgcgcgcc ctcgtccaca gcggccagcc gcagcagctg
     7621 ctcaagccga tccactgggt ggagcacttc aaggccaaga acccccagcg gcgcagccag
     7681 gccgcgcacg cgctcgcctc catacccaca gcccgtgtca tccatgtgat cgcgcacaag
     7741 gagaccttgc accaggacgc cgagctgcgg agggacaagg gcgtcttcta caactacacg
     7801 accaggctgc tgctggaacg cgtcgcctac ctggccaggg agtggcccgg cgggaagcgc
     7861 ctggcgatag tccggctcgg ccaggtcaaa cacatggacc accgggactg cgcgagctac
     7921 ctggatcggg tacgcagcgg cgagactttc ggcgtcccgt ggcaacacat caaatggcca
     7981 cccacctggg taaacaccgc ctgtaacggc attcagctcg ccgacgtcca cgccggcctg
     8041 ctcaacagcg cgctcagcgg gaacccccag gacaccgctt gcgcggaaaa cctccagaag
     8101 atcagccacc agctgcgccg atcggcgcgc ggtgacctgg acggctacgg gatcaaggtc
     8161 atcggggaca agcgtttcgt cacggaacgc gcctggtggc cggacctcaa gaaccggtga
     8221 aatgcacaaa gcccccgggg ggactcccgg gggccacaac cacctctggg ggtggaggga
     8281 tccagttccc tggttccggc cgtaatcccg gcagcccgcc taggggctct tgcgtgatat
     8341 caccctaccc gtagcagccc gattttcacc tgccgaatcc cgttcttgac cactcaatca
     8401 cccccccgat cgccggaatc gcactagttc ttgaggagag agtgagtgtg agcgagtcgg
     8461 ctgcccgtcg gtgcccctga aggattgcgc acagggccgc gagccgacag cggccgggac
     8521 gtcgggggat ccacccgctc agtggccttc cggcgcgatg tcccccggcc cgaaggcgac
     8581 cagaacgagg gcgccggtct cgttctggtc caccatccac cgctcggccg gggaggcact
     8641 cgccgcagcg gcgcggcgcc gaaggagcgc agaagcgtcc cagccggggt cccggacgcc
     8701 gcgaccctac gccgcgctcg gctgggcgac gctgcgcgcc ctcggtggca tcctcatcgg
     8761 agaggcaggc gtctacggcg gccccggtgg caagctcacc tagcgcccac ccgcccacgc
     8821 cgcactgcga cgcctcatcg caacgccccg ctgctgatca cgccctcaac cttggatggc
     8881 aaatgctcaa ggtgcgctgt cacaggactc tggggcagag acgggccccg actactgcct
     8941 cccaagggga aggacgccgg ccggggctgg ggcgatgaac cttagagggt caggcggagg
     9001 ttccagccgg tcaggccagg ctcgtcgtgg cttgcgaggc tgggggtgta cgtctcgggg
     9061 gccgggcggt cagcgtcctc ccaggcgctg agccagtcgc gcaggacgga cagggacgag
     9121 gagtcggggc cgtcggcgac gatagtgccg tcctgctgca ggacggcgac cgtggtgggt
     9181 gtggagtggc cgatggccca caggcccggg ttgatcccgg ccatggtcag gtgcgggtcg
     9241 gccggggatg cggcgtaggt ccgccaggac ggccagtcga cttcctcccc gctatacggc
     9301 tcggtgtgcg cgtccttcag cagccgcccc agcgcggtgc gggcaccggt gtggagccgg
     9361 tcgtcctgct cgcgccaggc gatggagatc caggacgggg cggggacgcg gttttcccag
     9421 tccacccagc ggccgggcag atccaggtcg gtcttcgggg aggcggtcgc ctcgatgtag
     9481 ccgccgttga ccacctgctc aacgaccggc tcgccgccat ggatgcggat cttggcgacc
     9541 acggtcatgt tgggcacggc tgcgatgggc agcggcgcga cgatcagccc accgtcgatg
     9601 acctggtcca cccacgcctt cggcagcagc ggtggggtgc accaggccac caggcggtcg
     9661 tacggggcgc gttcggagaa gcctgcggtg ccgtccgcga tgtgacagcg cacgttgccg
     9721 attccgcgtt cgtggtggat gaggttggcc cacttcacga ggtagttgtc gatgtcgagg
     9781 ctggtgaccg taccggtggg gccaacgagc tgggcgagga gggcgccgga gtagccggag
     9841 ccggttccga actccacgac gttcatggcc gattggacct ccagcgtggt cagctcgcgg
     9901 tggatggctt tggggttgga gcggttcgcg gtggctccgc ggccttcgtg gtgggtgtag
     9961 tggcgttcgg gaacggtctg ggcgacgtcg gcgacggcag tcactgttca ctccttcgag
    10021 gggtggggca ctcatacgcg acaaccgcct ggggcggctg atggatacgc gcccggcgcc
    10081 ccgggatcgt catgccggtg aggtagtgcc acccggccac ggtgtactcg ccgaccggac
    10141 cgtggtcagg cagctcggcc caggcgtggt gctcgaccgg cggcggggag aagcgggccc
    10201 cgatgcacca ggtgagacgt cggccgagca gggcagctgc gagcacggcg ccgagcgagg
    10261 tttccatgca ggcggcgcgt ccgggccacc atctggcggt gtgccgtacg gcaccgacca
    10321 gcgcctcggc tcgtgccggg gcgagcaggc gtcggccggc ctgggtggct aggcgggtgg
    10381 cgcggacggt gtgacggaag ggcagccgca gcaggacgag cgccagggtg aggcccgcgg
    10441 ctgccgccag acgctcgagg taggtcccgg tgcggacggt ggagtacgcc tccatgctgg
    10501 tcatcgccac ctccaccggc gccgccgcgg cggtgcctcc tcggcctgcg cgagaccctt
    10561 ggcagagagt ctgttcgcga cggtgcggat gtcggtggcg gcctgctcgg ccccgatgcc
    10621 gtaccgctgg gcgaagcggt gggccgcctg ttgctcggtc tggcaggaca gcaggagcat
    10681 cacggcggcg gctgcggtcg gggtgagctg ggtccagcgt ccggtgtgct cgtcgaggat
    10741 ggcgccgccc tggtcggtga ggatcgggtg ggcacgttca cgcagctgcc acacggggct
    10801 ttacctcctc ccaccagtgc ttgggcgcga aggccagttg ccgtagccag acctcggcgg
    10861 tgaccaccag gtggagggct ccctgggcgg tggactgccc ggcggcggcc cgcgcgagcg
    10921 ccgcggcgac ggggtactcg gtgaccagtc ccagcgcggc cagccgggag gagggtccca
    10981 gcaggtcctt gaggacccgg gcgtggtcgc gcaggcccgc gtaggcgagg gcgttgaacc
    11041 cgcccttcgt cgtccgggcc agtacgaagt ccggcagcac gccggttttg gtgaaggccg
    11101 ctgccagcag cggcttgtac tgtgcgggtt ctccgcgccg gtcggcgggg acggcaaggc
    11161 aggcccggat cacctcgttg tccaggtacg gggcggccaa ttcgatgcca tgctcggcaa
    11221 gggcgagcgc ccgccagcca gcggtgttgg tgccgacccg ggccaggtct tgccggtcgc
    11281 tccagtccgc cagccgcgcg ggggcgtcgg tgagctcttc ggcggcttgg tcgagggcag
    11341 tggcgaggcg gcggcgtacg tcgggggcca tccagtccgc cgaggccagc agcggtgtcc
    11401 aggcgatcgg ccgctgggct tggggaatcc agtcccgtgc ggggcggcgg agttcggcag
    11461 ccgtccgcat ccaggccccg gcgaggtcgg ttcgggccgc gtccttcacg cgggcgagga
    11521 cggtgaaggc ggaggtgtgc cgtagccggg catgcacgac cgcgtggcag agggcacgcc
    11581 ggtgctgccg ctcgcgcagc aggtccgcga ggtaggagga gggggcggac agcaccgcgt
    11641 ccccggccgc cccggtgaag tgcacccccg gtgtcgaagc ctgctcggcg acggtctcga
    11701 gcacggcccg tttgatggag gcggtgacca cgtaggcgtt gggtgcgtcg gtgacaggta
    11761 gcgctgtcag gtcgcccagc cctgcgtagt acaccgcctc ggcgttaccg ggcaccgtct
    11821 ggtgcaccag gcccggcacc gcggccgcgg tgcggtgtgc gtacgcgagg tcgtcgtcac
    11881 gtaggcgttc gtcggcgtat gtcaccgcgg tcaccggggc gtgctgggct gccaggcacg
    11941 cgagtgtggt ggagtccaga cccgccaggt ccgcgctcac gggccggtcg tcgatgcggg
    12001 cggcgactgc ctcggcgagc gcggcccgga ccgtcggggc cgcttgccgc agtgggaccg
    12061 gcggatacgc ggccgactcg taccgctcga ccatggcgcc gtcgggtccg atcatcagca
    12121 ggtgcccgcc cggcacccgc cgcaccgagc ggaacaggct gcggtcagcg aacacgtcgg
    12181 gctggctgaa ggccagatga gcggcgagtg cgttcacgtc gaccggcgcc ccgtccagtg
    12241 ctgccagcgc ggacgccgcg gtcgaccacc acgttccggc cgcgtcggtg cggtagtaga
    12301 ccgggtgctg gccggccagg tcgccgatca cggccagggt ttcgccgctg cgggcgacaa
    12361 cgaggtggga gccaggccag cgggtcagcg ctcgccactt acgcgcctgc accacgggca
    12421 gtgcgctctc cagctggcgg tcgtcggcgc cgcattcgcc gatcacggtc agagccatcg
    12481 ggccctggcc gacggaacgg acctgagcct tcggccaccc agtggtccat gtcgattcca
    12541 ggccgggcac cgcccggccc ctggcgggcc gccggtcatt cccagcgctg ccataccaac
    12601 ccgcgctcca cctcatcatc gccctctccc tcgtccgtgc gcgtatttgt gcgacaaggt
    12661 gaaggcgccg ggccgaccat ctcgtgcccc agcacgagaa cgacgttggc ccggcgcctc
    12721 ctttaagtgc cgggtcggcc gtggcgctca attcccgctg gccggacccg gcagtccgcg
    12781 ggctagtgct tgtactcggt gtcgtcggcg gtgtcgaagg gctgggtgcc cagcgtcacc
    12841 gtgacaacgt cgccggcatc cagcactacg ggcgcctcgt agacctcggt ggggtgctcc
    12901 atgacgaaat cccttcactc gccgcccggc ttcggtccgc cgggctatga cgaacagtca
    12961 acgcgcagac gcacagcgtg ggcagctgcc acaatgtggg ccagctgtag gccagttgtg
    13021 aacccgcacg accaacgatc ggccggacat gactatcggg gagcgcatcc gcgcggcacg
    13081 cgaagcacga cgtcccagat gcagccagca acggctcgcg gacgagctgt cggcggcgcg
    13141 ctggggaaaa ccagggtttc ttgaccggca gcaggtctac cggtgggaga ccgaacgacg
    13201 ggtgcccaag gagtggttgc agttcatcga acaggtactg caccttgatc tgtccgagga
    13261 caatgagacc cagctcgccg ataccgtgac ctcagtcatg ctcttgggag gcaccgacgt
    13321 ggaccgacgg cagttcctcg cagcatcagc agccgtgggc ctggccgcga tcgacctccc
    13381 cgacgccgag gccgtcaccc gccgcgcgaa ccgccccggc cccgtcgcgg tcggcatggg
    13441 cgaagtcgcc gcggtccgca ccatgaccac cacactcggc gacgccgcct ccgaactcgg
    13501 cggcggacac gcccgccacc tggccgtccg gtacctaacc ctcgacgtcc ggcgatggct
    13561 ggacggccgc tataccgaga aggtcggccg cgagctgttc gctgccacca gcgagctggt
    13621 gcacttgatc ggctggatgg ctcgggatga gggcagccag gggctgagtc agcagtacaa
    13681 cgtgcacagc ttcaagctcg ccgccgaggc cggcgagaac gagctcgccg cgaccgccct
    13741 gcggggcatg gcggaccagg ccatcgatct cggtcacgtg gcgacggccg tacggctcgc
    13801 cgaggcgtgc gaacagcgcg gccggaagct gaagaacccc aaggcgctgg cgtactaccg
    13861 caacacgctc gcccgtgctg ctgccgcgga cggcgaccgc acaaccgccg ggcgactgct
    13921 gacctcttcg caggcagcga tcgagcacgc cccgccccgc cctggccagt cgtgggcaag
    13981 ccactacagc cacggccggt gggcccatga gtctggcatg atccacgcca agctgggcga
    14041 ctacgccgcg gcggaggagc acttgcagct ggccatggag atccacggtc tcgaccgaaa
    14101 gcggacccgg gcgatcgtgc tcgccgacct cggccaggtc cagctcaagc gcggcaacat
    14161 ctcccaggcc ctggccacct ggagcgactt cctgacctgc gcggacggcg ttcagtccgt
    14221 ccgcatcaac gacggcctga ccaacatcgc cgcccgcctg ccgggaatcc cggacagccc
    14281 ggctgtgcag gaactcgccg agcgcatcgc gacacgtgcg tgaacgggcc tacgaaagcg
    14341 gccgttgctg ggcccagcaa cggccgctct gccttcgacc cgcccgaagc cggtgcccgt
    14401 acgggcaccg cctcacgcac acggagactg cccgtgacga cacgagctcg gcgttcgcga
    14461 atccgtccac cgcacccgca ctccttgcgg atcaccggcg gcatgccgcg tcgtcacccg
    14521 atgggccggt tctggtcgcg catcatgttc cgcaaggctg tgcgggcagc ggcgagatcg
    14581 tcgttagcca cctccacact cttctccagg ccggccttct caccacgcag gctgtcccgc
    14641 tcagcggtca atcgctgggc gatctgtgtc aactcttcta ttcgggctac caactcagca
    14701 ttcgtggctt ggtttagttg acgtccgaga ccgcgctgca tggccgcctt gagcttgtcc
    14761 cgttcctcac gcaggcggcg gatctccgct cgagccagtt ccaggtcggt ctgcaggctg
    14821 gccgtgctcg cagtcacccc ggcctgccgg tcctgcaccg ccttgtgagc ctgctgagca
    14881 cgggctttct cgatgtgctc gcgcacgcct tccgcgtaga ccagccagtt cgacaccccg
    14941 gccgtccggg cgaccgaggc gaacgtcacc ggatcaccct cggaaagcat ctggtccacc
    15001 accgacaaca cccgctcacg cttacgggtg ctgtccttgc ggcgcgcttc ccgcagcacc
    15061 tcagccggga tccggcgctc ggtcatccgg cttccgcctt gttcactact gtcagcggca
    15121 agagcttgcg cccctctccc gcccggacct tgcgaagcac cttactggcc tcctggatct
    15181 ccgcctgaac ctcgggcgga tactgcgcca tccgttcatt catccgttcc acaacgcctt
    15241 ggaacgcctc gatttgatca gtgaggttgc ggacaacgaa gtcgtcggta cccattgctg
    15301 tggccatctc gcgatctgcc ttcaaagacc ggacgtggtc ctcgattgct ggcagatagg
    15361 acgggtcggg gcgataaaaa ccgcagcccg cgcactgaaa tcgaatcggg cacttcttgc
    15421 cgcctgccgt cacattcgac ggctcgacgc agcccccaaa ggggacggcg accgacttct
    15481 tctcgtagga tatgccggag gataagggtg ctgggcgacc ggatcggtct accgtgtgac
    15541 ctcgcagcgt ctcgacggcc tcccgcttcc gcttgatggt aacccgatag taacccatgg
    15601 tggtttgcgc agacttgtgg tccatgagcg acatcaggac gtcgatcgga gtaccgacat
    15661 ccgcgtgcct ctgagcatag gaggaccgga aggcatacgg gtatatcttc tcccgatcga
    15721 agggcaacgg cttgccatcg tcgccagggg cgtctgagtc gatagctggt atcgcgtcga
    15781 cccatgcgcg catggcgttg gagaactccc ccgacttcat gtgacccaac ttggtttcct
    15841 cgttcatgac gggaaacaaa taacgcgcgt tggatggagg gacgtcaagt tttacgcgac
    15901 gttttttcca ggtcaaaatc gcctgcgcgg ttcgctcttc gatgggcaac aggcgacgta
    15961 ggcgcttgcc cttcttgttg tcccaacgga ggttgtattc acctttctcg tacttaaggc
    16021 aatccagggc caggccgcag aactccctag ggcgtcgccc ggtatccctg cagatgatgt
    16081 aggcggtctg catcatcagc atgacgtcgc cgggagcaag gccgccgcag ttgataccgc
    16141 gacccaactc tccaagattc gcgtcgagtt gtcggatcac cggttcgggg atggccttac
    16201 cggcttcatc ctcctcttcc tcgaccacga aggggatccg gtgaccagag tgggcagcga
    16261 atctcggatt cagatcgtcg agcaaccctt cgctgcggcc gaagctgagc aggtcaagga
    16321 aaccccggcg catctcagca cgcgacttgt agctgtagac cgttccattt ttcatctggg
    16381 cgtccacgaa tgccgcgatc acgctgtcca tgtccaaggt gccgagctgg gtcacgtccg
    16441 tgccgccgcc ggaccgcagg gccaagccgg cggaagcaaa ctcacaggac agcagcgtcc
    16501 tgcgcagatc gaggctatcc ggcgaggtca tcctgaccca ggacaagagc agggtccgca
    16561 gccaaggctg ctggagtccc gcgagcgaga ccacgccgcc acgagtccgc cgtcccgatt
    16621 tgctgtgcga cgaggccagc ccagctgtca gcagattgag ctctccgtca tgagatggat
    16681 cgacgccgcg gaacttgtcg aagccagccc gtagccacgt ttctgactcc gcgatgaaga
    16741 attcctcatt tgtgtcgggg ctctgaatcc gcggcaaggg cgagagcgcc aggctgtcca
    16801 gccctgccca cctgcggacc gccttacgca cagccttggg gtcaaggcgg gttctatgac
    16861 ggtcccgctc gcggatagcg tagagcgctt ccaaccgcac caacggagcc agcggagcta
    16921 atgaaaaatc gaactgcgtg agccacggtg tctcccactc tgcccacttc tggagcgtaa
    16981 cgggagcggt ggcgcccttg cagtgtctcc gatatcgctc ccggtggtgg gcgcagagga
    17041 gttccgacat cctcgtgcgc tgcagtgtgc atccggcaac aaggcagagc ggaaatgccg
    17101 gcctcggaac tgccatcgtg cgagcccaca cctccaacga gaccgcatct tcgccttcct
    17161 tatggcgccg ccaggcggcc cagtgtggag gacacatgcc cagagatgag gagtcgcgct
    17221 ggcaggcgcc ttgatcgcct gtcaccagac acctttcacg gatccccggc gacttctgca
    17281 accgtggaac gtagctagct gtgaactcgg gcttggccat cccgctagcc ttcaaggcag
    17341 tggcacattg cttgcacaga ccgtccttgg agtgcacgcc gagctcacat ttcacggtcg
    17401 cgcacttcca catagccgtg tggacactgc ctggatcccc gttgaagagc caggtcttcg
    17461 gattccactc gtgggggcgc cactcgtccg cgacgcgctc cgtgagccag agcttccatg
    17521 cttctagatc cacctgaaac ggtgcttgga caactcgcga atcccccgct gagacggcga
    17581 tttcactcat gggccgtctc ccgtgcagct gcgacccgtt ccacggccgc gcgtttgtcc
    17641 gtgtcgctcg cgtgcacgta gacatcgagc gatgacggcg actggtgccc caggaggtcc
    17701 tgcaccacat cccgaggctg cccttcccga atccacgcgg tagctgcgct gtgccgcatc
    17761 atgtgcggcc gcacggtgaa ccccacgcgc ttcaacaggc ggtcgaaaag atccttcgcc
    17821 cctgcatagg tcatcggccg accgagtggc ccccggaaga ggttgacaaa caccatgtcg
    17881 ctctcggccg cctcacgaac agcgacccgc tcatgtaggt actcggtgta gagctccacc
    17941 agtccctcgg tcacgggtat cgaacgggag cgaggcgact tggccaacgc gccattggtg
    18001 ttcagacgcc gtcgcacatg gaggtgtggt ccttcaacgt tgcacccaag gctgcgggag
    18061 ttcgacagaa agtgcatgtc ctcgcgccgc aagcccagag cctcaccgat gcgcaccccg
    18121 gtgacccaca gcagtgaaac gaggaatcgg tcccgatggc gggtcgttgc cccgatgacc
    18181 tcctccacct ggtcaggagt aagccattcg atgccctcgt cctctacctt gaacttgatc
    18241 tctcgtgccc ggaccgtgcg gaactggccg tcctcgccgg cgtcgtagcc tgccggcagg
    18301 tggctcaggt acttctcaga cgacagcctc gatacgacct cgtcacgcac ccatccacac
    18361 cgcgcgccga accgcaggaa ctcacacacg gtcgtcagta cagcgttggc agtcgccttt
    18421 gatcgaaacc gcggttccag gggcgtcttg cggcctcggg gcggcaatgg ctcatccacc
    18481 agccagtgca gaaaacgcgc aagctgattc agcgtcgggt tcgcccagcc aacaccgttg
    18541 gcagcgcagt gcgataggta cagcgcaacc cggcccccat aggtccgctc agtgttcacc
    18601 gacagcccgc gcgaccgcag ttggaatagg aaggccgtgc cctccgcgtg caggtcgtac
    18661 gtgaccgcat ccaccacgac ccaggacaca cggcctgaat caggcgaaat agccttctca
    18721 gcccgatacg tcggacttgc agaaccagac gtgccagatg tctctaacaa ctctcagata
    18781 cctctcagga gaagactcgc ccctactgaa accagacgtg ccagagggga agttgctcct
    18841 caagataacg agcgtcccca cggcgtactc cgccgtggtc attccccggt cgtcggccct
    18901 gatcgtgcgc caccgcgccc accaccgccg gaccgttcca ctccgaacca tgtccatccc
    18961 cctttggatg tcttctgctg atggatctct tctgctcgtt ggctgtcatc tgctggttga
    19021 ctgtcgtctg aagtgcggcg gcgggcgccg acgggcagtt gaggaagcgc cggtggcccg
    19081 gacggttagc cggtggtccg gtcggtgagc cggcatctcc tcccgcggcc ggtcccctgc
    19141 caccgccggt acgtacttca ccggccgcct tcaaatccgc agcgcccacc gctcagttgc
    19201 gccccagcaa gccgctcgcc aggccgatca gtaccggcgc cactccgagc gccaggaacg
    19261 ccggcaagaa gcacgccgac agcggcatgg tgaccagcac cccggcccgc cggccccggg
    19321 cgaccgccgc ccgggcctgc tccgcacgga gcccggcggc ggcccgggag gcagactcga
    19381 cggccggtac cccggatatc ccggcgcgct ccatacagcg cgccagccct tccgcgccgg
    19441 ggagttcggc cagccgtggc cagacggccg ccggctcacc gcccaggcgg agttccgccg
    19501 ccacctggcg cagccgctct gccaccggcc cgtcgagcga ccgacctact gcctcggccg
    19561 cttcgcgcgg cccggctccc gccgcgagac aggcagccag cagatcgccg gccggtgcca
    19621 gtgccgcgcg tacctcggcg gccgccaacc gcgccgcttc cgcaccgcgt tggtgtgcca
    19681 gacagcggtg cgctcccaag cccacggcga gtcctgccag gacgccgccc acgccaccga
    19741 cgaggatgac catgaagaga gccgctccca cgggtccggc ccactcgctc agccgaccgt
    19801 acgcagcgtc cttcgtcctc gtggctcgcc tgcgccacgg gaccccggcc gacgccctgg
    19861 gccgggccgc gtgaccgccg tatcgatccg gacgagcagc tgcccatacc gtcgagaccc
    19921 gtcgccttac gactcgcccg ctgcgcacct cccgcagcag cgccacggcg cagagcatcg
    19981 ccgtcatggc cgcgaccgcc atccccaccc tgtggacaac ttctgcgctc acctcaaccc
    20041 cctctcccga gcgccttccg cggccgcgac gatccgggcc gtccaggcca ctccgcccca
    20101 ttccaggaac ccgccgatca ccaggcagcc ccacccggcc ggcgtgtgca gcagcacccg
    20161 cagcgggtcg gcgccgagtg cgctgcccat caggagcccg cccccgggca gcagggcgag
    20221 catcagagca gtggctcggg gacccgccaa ctgggcgcgc agttcgtcgc gttgatcccg
    20281 ctgggcgctg agcccggccg cgacccgctc cagcccgctg gccagtcccg cgccgccctc
    20341 caccgccacc tgccagcacg cggccatgcc ggtcagcccc tcggcccccg gcagtcgcgc
    20401 cgtcgcacgc aacgcctggg ggacatcccc tccgtaacgc gctgccgcgg tcaccgccga
    20461 acccgccgct ccgagacccg gcgtccccgc ggcgagcagt gcctgggcgg gctgccgccc
    20521 ggcccgcaac tcccccgcca ccgccgcgca cagtgtgatc accgcggcag cccgccggtc
    20581 acgcgcacgt accgctccac gggcgatcag ccaccgccgg acgaggaacg cggccgccac
    20641 ggaagccagt ggcggaagcg cggagccgcc cagcacaccc agcaccagcc cggccggcag
    20701 acaccagagc tcccacccga cgtcccccag ggggcccacg cgccagcgcc gccccgcgtc
    20761 cccctcgacc acccgctgta ggcaccactt ccgcaccttc tgggcccgca tccgggcccg
    20821 ccatcccgct tcagcgtccc tctcgccgtg gctcccgaac agcgcccggg cccgccgccg
    20881 tacgtcgtcc ggccggcccc cggcgagccg gcccgcggct cccgcgcaga ccaccgcggc
    20941 catcagcgcc gccccctcgg ccgcgctcac cggaacccgc ccccgccccg ctcgcacaac
    21001 cgcatcaacc gcccccagcc gggcgcctcc tggaagccgg cggggctttg gaccgcggcc
    21061 ggtacggtca ccacgaagcc gtcccggtcc cgctccagga cgtggacctc ggcgatgcgg
    21121 cggcggccgt tccggtcgcg tacgagatgc aggacgaccg agaccgcggc cgccaactgg
    21181 ctgtgcagcg cggcgcggtc caggcccgcg gtcgatccga gggcctccag gcgcgcgggg
    21241 acgtcggacg cggcattggc atggaccgtg ccgcagccgc cctcgtgccc cgtattgagg
    21301 gccgccagca aatctgtgac ctcggggccg cgtacctcgc cgaccaccag ccggtccggg
    21361 cgcatccgca gcgcctgccg tacgaggtcc cgcagcgtca cccggccgac accctcctga
    21421 ttggcctgcc gggtctccag tcgcaccaca tgggggtggt ccggacgcag ctccgccgag
    21481 tcctcggcca ggacgatccg ttcgtccggg ccgaccaggc cgaggagggt gctcagcaat
    21541 gtggtcttgc cggcgcccgt accgccgctg atcaggaagg acagcctggc cgtcagaagt
    21601 gcgcggagca gttgatcgcc gcccggcggg accgtcccgg ccgctaccag ctccgcgagg
    21661 ccgaaggccc gcggccgcag tacccgcagt gacagacacg tcccggcgac cgccaccggc
    21721 ggcagcaccg cgtgcagccg ggtgccgtcc ggcagccggg catccaccca tggccgggca
    21781 tcgtccagcc gccggccggc caccgccgcc agccgctggg cgagtctgcg cacctctgcc
    21841 gcgtcccgga accggacctc cgtacgctcc agcccgccgc cgcggtccac ccacacctcg
    21901 tccggcgcgg tgaccagcac gtccgtgaca tcgggcgcgg ccagaagcgg ctccagcggg
    21961 ccgctgccca ccatttcgga gcgcagcccg gccactacac ccagcacctc ggcatccccc
    22021 aggagccgcc cctgctcgcg cagggccagc gccacccgcg ccggcgtcgg atccgccccg
    22081 tcctcggcga gccgccggcg caccgcctcc agcaggtcct ggccctggct catgtccggc
    22141 ctccgccccg gcagggcgcc tgctccggcc cgccgtccgg ctccgggacc ggacctgacc
    22201 ccgcaccggc tcccggcgcg cccccgctct ccgtcacccg ctcccagaag cccgcgcaga
    22261 accgcgccag cggaccgcgc agctgcgccc ccggcggcac cccgcgggca agatcggcca
    22321 acagccccgc ctcccacggc acttcacctg ccaggggcag ccccatcagg cgggcgatct
    22381 cgtccggcgg caggccgtgg ccatggcgtc cgggagcctc acaggccacc acccgcagat
    22441 cgccgagcac ctgctgcacc ccgaaggcca cccgctgggc ggccgccacc gcgcgcagct
    22501 ccgtggggac gagcagcagg cccatgtcca cctgggccag ggcctccgcc gccgcctcgt
    22561 cgaccctgcg cggcaggtcc accactacga cgccgccgcg ccggcgcgcc gccgccatg
//
