LOCUS       NZ_LT907981            24883 bp    DNA     circular CON 12-FEB-2024
DEFINITION  Streptomyces sp. 2323.1 chromosome I.
ACCESSION   NZ_LT907981
VERSION     NZ_LT907981.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. 2323.1
  ORGANISM  Streptomyces sp. 2323.1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 03:31:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,058
            CDSs (total)                      :: 6,971
            Genes (coding)                    :: 6,808
            CDSs (with protein)               :: 6,808
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 163
            CDSs (without protein)            :: 163
            Pseudo Genes (ambiguous residues) :: 0 of 163
            Pseudo Genes (frameshifted)       :: 64 of 163
            Pseudo Genes (incomplete)         :: 123 of 163
            Pseudo Genes (internal stop)      :: 17 of 163
            Pseudo Genes (multiple problems)  :: 37 of 163
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 502302
            Orig. end                         :: 527185
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT907981.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24883
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24883
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24883
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14883]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14883
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    358..371
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            complement(1403..2401)
                     /locus_tag="CPH93_RS01660"
                     /old_locus_tag="SAMN06272775_0366"
     CDS             complement(1403..2401)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607863.1"
                     /locus_tag="CPH93_RS01660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0366"
                     /product="xanthine dehydrogenase family protein subunit M"
                     /protein_id="WP_093487889.1"
                     /transl_table=11
                     /translation="MRAISYTRATDVPGAVAAVTNDPGSSFLAGGTTEVDLLRLDVLRP
                     NRLVDINRLPLADIEDRADGGLVIGALARMSEVAEAPGVVERYPMLSQSLLLGASAQLR
                     HMASMGGNLMQRVRCSYYRDPESACNKRVPGSGCSALEGVHRGHAILGTSEHCIATHPS
                     DMAVALVALDAVVQVEGVKGTRTIPVDDFFLLPEDTPEREHPLTPGELITAIEVPALPM
                     ARRSLYLKVRDRESYEFALASAAVALALEDGVIRGVRLALGGVATKPWRAHRAEEMLLG
                     QPADEDTFARAAAAELAPAVTRPMNAFKAELTRRTVVRALRTAAALRGEQA"
     gene            complement(2403..2894)
                     /locus_tag="CPH93_RS01665"
                     /old_locus_tag="SAMN06272775_0367"
     CDS             complement(2403..2894)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091554.1"
                     /locus_tag="CPH93_RS01665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0367"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_096211693.1"
                     /transl_table=11
                     /translation="MEIRGPDGVQMDLVVNGVSRVLYLEPRVSLLDALREHMALTGTKK
                     GCDQGTCGACTVWVDGRRVLACLTLAITCEGRDVTTIEGLAEGNELHPMQRAFLEHDAL
                     QCGYCTPGQIMSAVALLKEGHAETDREIAEWMSGNICRCAAYPHIRSAIREVRDRKTGQ
                     "
     misc_feature    complement(2849..2863)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     gene            3082..3540
                     /locus_tag="CPH93_RS01670"
                     /old_locus_tag="SAMN06272775_0368"
     CDS             3082..3540
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058273.1"
                     /locus_tag="CPH93_RS01670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0368"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_096211694.1"
                     /transl_table=11
                     /translation="MRISARADYAVRAALHLAAARDAGPLKAEAIAHAQDIPHKFLEGI
                     LNDMRRGGLVHSQRGGNGGYRLAKPAEAISIADVIRVVDGPLVSVRGVRPPELSYTGPA
                     ESLLPLWIALRANVRQILDGVSLADVASAELPSRVSVLTEDPASWENP"
     misc_feature    complement(3599..3612)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(3668..3686)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.83"
                     /tool="antismash"
     gene            3774..5039
                     /locus_tag="CPH93_RS01675"
                     /old_locus_tag="SAMN06272775_0369"
     CDS             3774..5039
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607866.1"
                     /locus_tag="CPH93_RS01675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0369"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_096211695.1"
                     /transl_table=11
                     /translation="MPKKSAAGAGSAPAGRLVDEALRPRLTREVADDLAVDALLRDRAG
                     KPPFDEAARLREAGLPALLTPPGPDRRGTDWRTACGVIREIAAADSSIGELLGRHYALS
                     WSARFFSTPERADALERRAVAEQWLWGGSTDVPGAEAATEDGLTLTPADGGYVLSGGTT
                     LAAGVQVADRLVLGGVGTDTGDSLIVCLDPERPGVTADAEHDRLGQRLAGAGSISFDDV
                     LVPADEVLGTVPRDEHAVSPFATLAPLALRLALVHVSLGTAEGALAEARDSNRAAPGRW
                     PVPGPDESAYPDRPGADPYLLLAYGELVTAAHTAAAVVESATEALAQGLLTGPALGVDE
                     RADIAVLVAAAEATTGRSAMQITTRIMELTQGAGSAADTLGFDRFWRNARILTAQASPT
                     HRLRDIGDHYLNGTHPPLTLRA"
     misc_feature    3775..3791
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.18"
                     /tool="antismash"
     gene            5240..5752
                     /locus_tag="CPH93_RS01680"
                     /old_locus_tag="SAMN06272775_0370"
     CDS             5240..5752
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091557.1"
                     /locus_tag="CPH93_RS01680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0370"
                     /product="hypothetical protein"
                     /protein_id="WP_231977141.1"
                     /transl_table=11
                     /translation="MSESSSVPVQPGRRATFLQRMLFGGVYGSVLASALAGALSHEGTD
                     PGYDAAWVTLSAVAAAAAHGYAHSIAHRTEDDTHATASAVVSMLTEWPLVAAMLPTIAA
                     LLGAYATWWTEAGAVEVALTINMVALFGWGLWAARVAGRGWWASLRVGGVDVLIGLFIV
                     IANTLSK"
     gene            complement(5814..6743)
                     /gene="tgmB"
                     /locus_tag="CPH93_RS01685"
                     /old_locus_tag="SAMN06272775_0371"
     CDS             complement(5814..6743)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="tgmB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607868.1"
                     /locus_tag="CPH93_RS01685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0371"
                     /product="ATP-grasp ribosomal peptide maturase"
                     /protein_id="WP_096211696.1"
                     /transl_table=11
                     /translation="MTVLVLTCEEDLTADIVVATLHELGVPLVRLDPADLPGRVSLSAE
                     YADNDFHGYLKSGERMVSLNSLRSVWVRRPGVPGARSAEQSAWITAEAEQALYGMLSCT
                     DARWMNHPTAAAQARYKPWQLHIAHRSGFLVPPTLLTSFPSAARQFAATHRDLVVKSVS
                     GKHPGDPPMVLPTTRISPDTDFSGVAAGPTLLQRHVPKEADIRLTCIEDQLFAARKKAD
                     PEEVDSRFTHHGTWEAAEVPDAVQRAVLAYMNAAQLAYGAFDFAEDPDGTWWFLECNQG
                     GQFGFVQLETDQPIAQAIAGWLAVKSAL"
     gene            complement(6750..6941)
                     /gene="tgmA"
                     /locus_tag="CPH93_RS01690"
                     /old_locus_tag="SAMN06272775_0372"
     CDS             complement(6750..6941)
                     /codon_start=1
                     /gene="tgmA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979382.1"
                     /locus_tag="CPH93_RS01690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0372"
                     /product="putative ATP-grasp-modified RiPP"
                     /protein_id="WP_040901932.1"
                     /transl_table=11
                     /translation="MRPFALSYARPAVKSATSTPYSYDATRQLNVLPDGRPATCSRAVL
                     LATGTTASTAGSKTHFDD"
     misc_feature    complement(6946..6959)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.45"
                     /tool="antismash"
     misc_feature    complement(6952..6961)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    complement(6955..6966)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.68"
                     /tool="antismash"
     gene            complement(7206..7910)
                     /locus_tag="CPH93_RS01695"
                     /old_locus_tag="SAMN06272775_0373"
     CDS             complement(7206..7910)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607870.1"
                     /locus_tag="CPH93_RS01695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0373"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_096211697.1"
                     /sec_met_domain="PF00561 (E-value: 1.4e-05, bitscore: 23.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTGPERPTDPTGGQDPHRPLVVHHRPDTPQAAVLLLHGGRPDDH
                     TPPTRLNLPALRMRPFGCALSRTPRGREVLLASVRYRCRGGNGPQADVAQDARAALDEL
                     AGYAPDVPVVLVGHSMGGRAALLIGGHRAVRGVVALAPWCPPGEPVSHLRDRTLVLLHD
                     VRDRITDAEASWHFADRARRAGARVHTVAMPRGGHTMLRGARHWHRLTVDLVAALLDGT
                     PVRDAVDGTGPG"
     gene            complement(7907..>8110)
                     /locus_tag="CPH93_RS01700"
                     /old_locus_tag="SAMN06272775_0374"
                     /pseudo=""
     CDS             complement(7907..>8110)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091561.1"
                     /locus_tag="CPH93_RS01700"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0374"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="ACGTWQAAAVAVVSPLVMSYLLTLGSGKRLLENQLAGRPGYAAYR
                     ARTSGFFPLPARRHPDPEDLRP"
     gene            complement(8387..9133)
                     /locus_tag="CPH93_RS01705"
                     /old_locus_tag="SAMN06272775_0375"
     CDS             complement(8387..9133)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607873.1"
                     /locus_tag="CPH93_RS01705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0375"
                     /product="anti-sigma factor"
                     /protein_id="WP_096211698.1"
                     /transl_table=11
                     /translation="MSTVELHTLTGAYALGALTGREAAEFARHLDRCAACAQEVRELQE
                     TAARLALAVAEVPPAALRTRVMAALPTVRQLPPADHGTTVVPMRRRFRHRLPYLAAAAC
                     LVGAAVAGGYAVQARHDAQEQRDRNVRAEQQAAVVSALMTAPDATFHTTALKGGGSGTV
                     VASKRMGRTAFLYHGLPALSGQRVYELWYSRNGQMVPAGLVETGSSSGTLLLTGGPQGA
                     DGVGVTAEPPGGSSRPTSSPLALLGV"
     gene            complement(9130..9720)
                     /locus_tag="CPH93_RS01710"
                     /old_locus_tag="SAMN06272775_0376"
     CDS             complement(9130..9720)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607874.1"
                     /locus_tag="CPH93_RS01710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0376"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_093487875.1"
                     /transl_table=11
                     /translation="MPVAARRGDRSPAPHAGALESLLDRVSRGDQQAFESLYTAVAGTV
                     LGLVRRVVRDPAQSEEVAQEVLIEVWRTAARFDPRQGSAMAWIMTLTHRRAVDRVRSVQ
                     AAADRDHRAGVHGYTTAFDEVSEQVERRLEREQVRRCLGQLTELQRESVTLAYYRGYTY
                     RETADLLGTALGTVKTRLRDGLIRLRDCLGVSA"
     misc_feature    9736..9748
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     gene            10001..11188
                     /locus_tag="CPH93_RS01715"
                     /old_locus_tag="SAMN06272775_0377"
     CDS             10001..11188
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607875.1"
                     /locus_tag="CPH93_RS01715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0377"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_096211699.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 2.5e-95, bitscore:
                     318.4, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDADAVIVGAGAAGLSLAHRLCAPSTGPGPRVVLVEAPPGPRTP
                     PERTWCYWEAPGGAFDGALTASWQRLRVHGPGGAATVGNPAPLRYKMLRSRDFEALVGA
                     RLSGRDTVVRVEATVESVRDVPGGAEVRGRDTAGRPVLLRARWAFDSRPAGRLPPARTT
                     LRQHFRGWFVHTRRPAFDPATADLMDFRTPQPGHGLSFGYVLPLSDRAALVEYTEFSRR
                     IADTAAYERALRHYTERVLRLGAFHVTGTEQGAIPMTDGRFPRRAGRAVFRIGTAGGAT
                     RPSTGYTFAAVQRQSALIAAALLAGRAPVPPAAHSPWHRALDAVLLRALDSGRVDGAEF
                     FTGLFRTVPTARLLRFLDGRSRLWEDLTIGLRTPVLPMLRTVAELPLLPRRAALW"
     gene            11260..12822
                     /locus_tag="CPH93_RS01720"
                     /old_locus_tag="SAMN06272775_0378"
     CDS             11260..12822
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971148.1"
                     /locus_tag="CPH93_RS01720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0378"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_096211700.1"
                     /sec_met_domain="DAO (E-value: 2.9e-08, bitscore: 32.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPRQRHDGAARRGRDRRAHRVPGPPGRDRAAPHGPRVAVIGAGI
                     AGLAAATALAERGAGVTLYERERSLGGRLAGWPVRLADGSPATMSRGFHAFFPQYYNLR
                     GLLRRVDPGLDMLRRLPDYPLHHRSGLRDSFARVPRTPPWSALGFVALSPTFGWRDLLR
                     MDPGAALPLLDVRVPQVYARLDRVSARDFLARIRFPEAARHLAFEVFSRSFFADPGELS
                     AAELALMFHIYFLGSSEGLLFDVPGEPFPQALWDPLGRYLAGHGAALRTDTEVVRVEPA
                     ADGGGLCVAGERAEDRFDSVVLALDPGGLRRLVAASPLLGDAAWRARIGRLRTAPPFLV
                     SRLWLERRVRADRPGFLGTSGFGALDNVSVLERWEGEAARWSARTGGSVLELHAYAMAP
                     DADRAREQRALVSQLHAVYPETRGTRIVDERHEWRADCPLFPVGGYGDRPTVHTPDPRV
                     VVAGDVVRTSFPVALMERAATTGFLAANALLARWGVRGQTLWSVPGKGRSAVLRWAARQ
                     AGR"
     gene            complement(12866..13873)
                     /locus_tag="CPH93_RS01725"
                     /old_locus_tag="SAMN06272775_0379"
     CDS             complement(12866..13873)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607877.1"
                     /locus_tag="CPH93_RS01725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0379"
                     /product="DUF5914 domain-containing protein"
                     /protein_id="WP_096211701.1"
                     /transl_table=11
                     /translation="MSRPRRPHPRLPLRLRRSPQPWAQQRPTWPDAKPAVIADAVKAAL
                     ARPSGNWFVLGAARDIAAGRAFGRTVAGVEVVAWRDAAGRLVAGPGACPHLGAPLALGP
                     VHGGILRCRWHGLALDGAPFAGWEPFPAHDDGLLVWVRLDEAGGELPLPEPVIPARPRP
                     AGAVAAVHTATGCCEPEDVVANRLDPWHGAWFHPYSFADLTVTGLPADGERAEGLAVEV
                     SFRVAGRAVVPVTALFTAPEPRTVVMHIVAGEGRGSVVETHATPLGPDDRGRPRTAVIE
                     AIVATSRRPGFALARAAAPALRPLMRAAAARLWRDDLAYAERRWELRSSGRHPG"
     gene            complement(13870..14883)
                     /locus_tag="CPH93_RS01730"
                     /old_locus_tag="SAMN06272775_0380"
     CDS             complement(13870..14883)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607879.1"
                     /locus_tag="CPH93_RS01730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0380"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_096211702.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.9e-119,
                     bitscore: 396.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 9.2e-62,
                     bitscore: 207.6, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDRELDAAGITDPLLRAAYAHCRRLNSRHGKTYFLATRLLPAAR
                     RPAVHALYGFARWADDLVDEPGAGRTTAGRAAALDALQQCLEDGLRGAPTTEPVVRAVV
                     HTAARYGIDHQHFRDFLASMRSDLTVTDYPTYADLRRYMHGSAAVLGLEMLPVLGTVVP
                     HEEAAPHAAALGVAFQLTNFLRDVGEDLDRGRVYLPAELLAAHGVDRGLLRWSRDTGAR
                     DPRITAALVAAADLTQGVYREAAPGLALLDPPSRPCIRTAFVLYGAILDAVRDDGYAVL
                     HRRAVVTRRRRAATAAGGLARVAATRLTARLTARRSAVSPGDPPRQVPVPVPEEAP"
     gene            complement(14880..16415)
                     /gene="crtI"
                     /locus_tag="CPH93_RS01735"
                     /old_locus_tag="SAMN06272775_0381"
     CDS             complement(14880..16415)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607880.1"
                     /locus_tag="CPH93_RS01735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0381"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_096211703.1"
                     /sec_met_domain="DAO (E-value: 7.6e-17, bitscore: 60.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVPGRTDHVVVVGAGLSGLSAALHLLGAGRRVTVVECEERPGG
                     RAGRIERNGYHLDTGPTVLTMPDLLDEAFAAVGERLTDRLELRALHPAYRARFADGSEL
                     AVHTDPGAMEAEIERFAGAGAAHGYRRLRRWLQQMYALQRHRFIDANFDSPLQLLHPDL
                     VRLAALGGFGRLDARIGRFLPDPRLRRVFSFQALYAGVPPARALAAYAVIAYMDTVAGV
                     YFPRGGMHALPQAMADAAADAGAAFHYGQRVTGLDRTGDRVTAVLTAHERIPCDAVVLT
                     PDLPVVHRLLGRRPHRPLRLRHAPSAVVLHAGTDRTWPHLAHHTLSFGAAWERTFDELT
                     RTGRLMSDPSLLISRPTASDPQLAPPGRHLHYVLAPCPNTETGPGARTWHDLAPRYRDS
                     LLAVLERRGLTGFGVAIEEQHLVTPADWTAQGLAAGTPFSLAHTFAQTGPFRPRNLVRG
                     TENAVLAGCGTTPGVGIPTVVLSGKLAAARITGPWSPRSAALPSRPALRGTPA"
     gene            complement(16440..17669)
                     /locus_tag="CPH93_RS01740"
                     /old_locus_tag="SAMN06272775_0382"
     CDS             complement(16440..17669)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (65-407). E-value:
                     9.7e-58. Score: 188.0. Matches aSDomain:
                     nrpspksdomains_CPH93_RS01740_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607881.1"
                     /locus_tag="CPH93_RS01740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0382"
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_096211704.1"
                     /sec_met_domain="t2fas (E-value: 1.4e-129, bitscore: 431.1,
                     seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.1e-50, bitscore:
                     171.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGPCREVAVTGLGVVSPAGIGARATWEGLLTGRSTAARDPGLAG
                     LPVDISCQVPDFDTARLVGRKAAWRLDRFVAMALLAARHAVADAGLAPADWDAARVGVV
                     IGTGTASMERYVGEFAKLAAGRPLDISPLAVTRSVPNMAAAEIALDLTATGPNFAVSTA
                     CASGSSALGVARDLLRAGTCDIVLAGGAESARHPIPAACFHRMGALSPRVADPAGACRP
                     FDAGRDGFVLSEGAAVLVLERPDHARARGARPRAQLAGYGATCDAYHYAAPDPEGRGAA
                     AALTAALADAGLTPGDIDHVNAHGTGTRLNDLAEARALHAVFPAPPAVTSLKGALGHAI
                     GAAGAIEAAVTVMSLQESTIPPTANHEDRDLDIDLDIVAKAPRSTPLSAAASTSFGFGG
                     QNAALVFRSV"
     aSDomain        complement(16449..17474)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPH93_RS01740_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="9.70E-58"
                     /label="CPH93_RS01740_PKS_KS.1"
                     /locus_tag="CPH93_RS01740"
                     /protein_end="407"
                     /protein_start="65"
                     /score="188.0"
                     /tool="antismash"
                     /translation="KAAWRLDRFVAMALLAARHAVADAGLAPADWDAARVGVVIGTGTA
                     SMERYVGEFAKLAAGRPLDISPLAVTRSVPNMAAAEIALDLTATGPNFAVSTACASGSS
                     ALGVARDLLRAGTCDIVLAGGAESARHPIPAACFHRMGALSPRVADPAGACRPFDAGRD
                     GFVLSEGAAVLVLERPDHARARGARPRAQLAGYGATCDAYHYAAPDPEGRGAAAALTAA
                     LADAGLTPGDIDHVNAHGTGTRLNDLAEARALHAVFPAPPAVTSLKGALGHAIGAAGAI
                     EAAVTVMSLQESTIPPTANHEDRDLDIDLDIVAKAPRSTPLSAAASTSFGFGGQNAALV
                     FR"
     CDS_motif       complement(17160..17207)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPH93_RS01740_0001"
                     /evalue="3.40E-03"
                     /label="PKSI-KS_m3"
                     /locus_tag="CPH93_RS01740"
                     /protein_end="170"
                     /protein_start="154"
                     /score="10.2"
                     /tool="antismash"
                     /translation="GPNFAVSTACASGSSA"
     gene            complement(17669..17932)
                     /locus_tag="CPH93_RS01745"
                     /old_locus_tag="SAMN06272775_0383"
     CDS             complement(17669..17932)
                     /NRPS_PKS="Domain: PP-binding (6-69). E-value: 3.1e-13.
                     Score: 41.8. Matches aSDomain:
                     nrpspksdomains_CPH93_RS01745_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607882.1"
                     /locus_tag="CPH93_RS01745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0383"
                     /product="acyl carrier protein"
                     /protein_id="WP_096211705.1"
                     /sec_met_domain="PP-binding (E-value: 3e-10, bitscore:
                     39.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTSTELITTTLTETFDLDPADVTPERTFEELGLDSLALVEMGLM
                     LQERTGISLDDVPLQTTIAGLAELMDRNEADQALTAAPNSTS"
     aSDomain        complement(17726..17914)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPH93_RS01745_PP-binding.1"
                     /evalue="3.10E-13"
                     /label="CPH93_RS01745_PP-binding.1"
                     /locus_tag="CPH93_RS01745"
                     /protein_end="69"
                     /protein_start="6"
                     /score="41.8"
                     /tool="antismash"
                     /translation="LITTTLTETFDLDPADVTPERTFEELGLDSLALVEMGLMLQERTG
                     ISLDDVPLQTTIAGLAEL"
     gene            complement(18202..19803)
                     /locus_tag="CPH93_RS01750"
                     /old_locus_tag="SAMN06272775_0384"
     CDS             complement(18202..19803)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091577.1"
                     /locus_tag="CPH93_RS01750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0384"
                     /product="MFS transporter"
                     /protein_id="WP_231977142.1"
                     /transl_table=11
                     /translation="MTTTGPAGPARRAGAAAVVCLGLFMLGLDLTVLNVAVPDLQGDLD
                     TSTAQVQWIVDGYALVLGGTVLAVGAFTDAWGRRRSFVCGVTVCAGASLGGALAGHPWQ
                     VIAARCVMGAGAALLMPATLAVLHHLFPEPRLRSRAIAAWAAVGGMGGLCGPVIGGWLV
                     EHYSWRAAFWINLPLAGVIVVLALALVPESRTVQRAGFDVPGAALSAAGLLALVWAITE
                     SPHRGWTSPAALTGFAAAALLLAAFVARQLRTPAPMLPLYLLRVPGIGVAAAALALMSF
                     AMFGALFVLTLYLQGVLGFSPWQAGLRTLPLPGGLALGAVCAVPLRTRLGGRIPVVAGL
                     TLVTAGFAVLATTTPDSGYPHCAVFQLVAGVGAGLVAAAATESVMGSVATERAGLGSAI
                     NDATRQVGSALGVAVQGSLLAAVFTSRLSTSLTGLHAPTLVTAAAEHSMLSVPEQARRL
                     PAPLRAGVLSAARSAFTDAMTLTAVVAGAVTLLTAAAAARWLGRPPRPHDARRATPPAP
                     RALAADQGRTPGAPER"
     gene            complement(19800..20615)
                     /locus_tag="CPH93_RS01755"
                     /old_locus_tag="SAMN06272775_0385"
     CDS             complement(19800..20615)
                     /NRPS_PKS="Domain: Thioesterase (33-258). E-value: 2.3e-40.
                     Score: 131.3. Matches aSDomain:
                     nrpspksdomains_CPH93_RS01755_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607884.1"
                     /locus_tag="CPH93_RS01755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0385"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_093487859.1"
                     /sec_met_domain="Thioesterase (E-value: 1.1e-39, bitscore:
                     135.6, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7e-07, bitscore:
                     28.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVGFTQESTSVPAAATAVPERVVLAARPQAALRLYAVPPAGAGP
                     DCYLRWAPLLPPWIELCSVALPGRGTRAGEPSLTDPAYLSARLAAVLDDWTDPRPFAVF
                     GHSAGALLAYEATRHLRRTHGRPPALLAVSSLSAPHLDAYTADLPPRLTAGLAGLRELV
                     GPIPEQLLADARLMAAACTPLLADLLLLLHYRHHPEPPLPVPLALYGGEHDPVTGLRQL
                     QAWNDLVTTPASAQLFPGGHSYLHTATKELVGHLTDVLGTVINRPVATA"
     aSDomain        complement(19842..20516)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPH93_RS01755_Thioesterase.1"
                     /evalue="2.30E-40"
                     /label="CPH93_RS01755_Thioesterase.1"
                     /locus_tag="CPH93_RS01755"
                     /protein_end="258"
                     /protein_start="33"
                     /score="131.3"
                     /tool="antismash"
                     /translation="RLYAVPPAGAGPDCYLRWAPLLPPWIELCSVALPGRGTRAGEPSL
                     TDPAYLSARLAAVLDDWTDPRPFAVFGHSAGALLAYEATRHLRRTHGRPPALLAVSSLS
                     APHLDAYTADLPPRLTAGLAGLRELVGPIPEQLLADARLMAAACTPLLADLLLLLHYRH
                     HPEPPLPVPLALYGGEHDPVTGLRQLQAWNDLVTTPASAQLFPGGHSYLHTATKELVGH
                     LTD"
     CDS_motif       complement(20256..20318)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPH93_RS01755_0001"
                     /evalue="4.20E-06"
                     /label="NRPS-te1"
                     /locus_tag="CPH93_RS01755"
                     /protein_end="120"
                     /protein_start="99"
                     /score="19.3"
                     /tool="antismash"
                     /translation="PFAVFGHSAGALLAYEATRHL"
     misc_feature    complement(20600..20614)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.63"
                     /tool="antismash"
     misc_feature    20787..20803
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.12"
                     /tool="antismash"
     misc_feature    20925..20940
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 25.23"
                     /tool="antismash"
     misc_feature    20925..20941
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 26.3"
                     /tool="antismash"
     misc_feature    complement(20926..20941)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.07"
                     /tool="antismash"
     gene            21269..22237
                     /locus_tag="CPH93_RS01760"
                     /old_locus_tag="SAMN06272775_0386"
     CDS             21269..22237
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607885.1"
                     /locus_tag="CPH93_RS01760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0386"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_096211706.1"
                     /transl_table=11
                     /translation="MASRPRSGRLLRTLLAALVAASVAVPVSGAARPAAVPAPAPVALA
                     PLRAAGPGALAERYAVNRAGIRAAARMADGHGDRARARALRRMAGPARQFLSFDGRGGG
                     RTAEVFGDLARAERIAVLVPGSDTNLDTYARFQAGATALRRTLDDRSAVVAWLGYETPG
                     TVSPEVVTPGRAASAAPQLRSFLGEMVALRPSARISVLCHSYGSVVCGRAAPGLKVANL
                     VLYGSPGAGVDSASALHTWATVWAGRGEGDWIAEVPHGQLDLPFTTLGLGADPVSDAFG
                     ARVFAAGAGGHSDYLAPGSVALRNIARIVSGRAPSGERRDA"
     gene            22230..23399
                     /locus_tag="CPH93_RS01765"
                     /old_locus_tag="SAMN06272775_0387"
     CDS             22230..23399
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607886.1"
                     /locus_tag="CPH93_RS01765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0387"
                     /product="acyltransferase"
                     /protein_id="WP_096211707.1"
                     /transl_table=11
                     /translation="MRELARRIAAATPDGRDRGVDALRALAILGVVLGHWLVTALVTDS
                     GAVHGASPLHSLPQLTPVSWVFQTLAVFFLVGGRMAATSHAAARARGESYGRWLGARTA
                     RLFRPVAAVVLLWCVVLVALLASGAGLETVRTLGTLAWSPLWFLLVFIALTAATPLVAG
                     LHPLWPLAVVLHIDLLRFGLGGPEWLGWLNVPAGWLVPYCLGAAWARGRLGGRTTGWML
                     LLGGGAATAGLVGWAGYPAAMVGVPGAGISNLNPPTLAAVTFGLAQCGAALLLLGPLRR
                     VLQRPLVWAPVALLNLSAMTVFLWHQTAMMAVTALGLLAGRPLPGLHTAPDGVSWVLAR
                     LAWLPVFGVALLVCGAAFRGYEQGRAGRRGRARAVPERRPALSAAGRRV"
     gene            23410..24726
                     /locus_tag="CPH93_RS01770"
                     /old_locus_tag="SAMN06272775_0388"
     CDS             23410..24726
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607887.1"
                     /locus_tag="CPH93_RS01770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN06272775_0388"
                     /product="sensor histidine kinase"
                     /protein_id="WP_096211708.1"
                     /transl_table=11
                     /translation="MITGGVKGGEPRWRTALLAVPRTLRDDLWTAAADPLPKLSRPRLL
                     ARLPHAVIGVLAYATGVLTTDFLTHVYGLVPGLALLLALCQSAALLAAMFRPIPAWWMS
                     TAAMAVGAVAARSDLPWEAGFPWTEPGILAQAATAFLLALRVRPRVAAEALGINVLAGL
                     GCLMFLGQGQHENLTQAVSLLVIATVLGAALRGRRVARSQLVAQEELTAEERARRTLLE
                     ERNRIARELHDVVAHHMSVISIQAQVAPHLVTDPTDELKENLAGIRANAVDALTELRRV
                     LGVLRSEDPSGEGVRHAPQPTLGRLDELIANVTAAGLTVTTETTGEPHALSPGAELSAF
                     RIVQEALSNAMRHAPGATVQVQLGYGSAGLTLRVTNTAPDGPAPPSPGSGHGLLGMRER
                     TAMLGGELAAGRTPDGGYEVTALLPAPARTPADAGEDTP"
     misc_feature    24809..24823
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 acggcggagc catcggcgta gagacgggcc cgggcgcgtt gcggctgcat ggggaagaac
       61 accgggtatc cggcggtggc catgcccttg ccgatcagcc agttgccgtc ccgctcggag
      121 cggagttcgg ggttgcggga ctgccagtcg aagcgggccg cgccgcggcg gtagcactcc
      181 tgcgcgccgt cgctcgacca ggggtgaccg gtgttggggt cggcgtgggc gtggttgcgc
      241 agccgcagct gtaccgggtc gacgccgatg cggtgggcga gctcgtccat cgtgcattcc
      301 agggcgaaca tccccgtcgt ctcaccgggg ccgcgggtga aggtgggcgt catggtgttg
      361 ctgcggatca gccggtacac gccctcgtag tgggggcagg cgtacgcctg cgcggcaata
      421 ctgagcgagg gttcggccca ctcgtcgaac ggcgaggtca gcgacagctt gtggtggcgc
      481 agtgcggtga gccgaccgtc gtccgtcgcc cccagttcga tgcgttgttc ctgctcttcg
      541 cggtggccgc aggaggtggc catctgctcc cgggtgagcg ccagtttgac cgggcgccgc
      601 acccatcgtg cggccatggc cgccagggtc acatgcggcc agatcatggc cttgcagccg
      661 aatccgccgc cgacgaacga ggcccgcacc cgcaccttcg acggggggat gcccagcagc
      721 gccgcgacgg tgcgctggct ggccacgatg ccctgggtgg cgtcatagag agtgagccgg
      781 tcgccgtccc agaccgccgt ggtggccgag ggttcgatgg ggtggtggtg gttggcggcg
      841 aagtggtagg tggcgtccag gcgttgggcc gccgccgcga agccggcctt gatgtccccg
      901 cgcacgctgc gggcgggcac gaaccccgcg aagatcgcct cgggttcgta ggcctggtcc
      961 cggccctctt cgagggtggt gacggaggcg tcgcgcgcgt agtcgacatg gatctgccgg
     1021 gccgcgaact gggcgcgttc ggacgaatcg gcgatcacca tggccaccgg ctggccgaag
     1081 tagtgcacga cctcgtcctg catcgggaag aagctctccc cgggggcggc atggccggcc
     1141 agggacggca gcagatgcgg tggggcggcg accttcggca ggttccggtg cgtcagcacg
     1201 gcgagcacac cgtcggcgtc ttcggcggcg ccggtgttga tgccgatgat ccgcccgctg
     1261 gccgtacggg cgccgacgag ggccgcgtag gcggtgccgg gcagggtgaa ttccgctgcg
     1321 tagcggccgc ttccggtgac tttcgcggga ccgtcgacgc ggtcgagggg ccggccgacg
     1381 gcttcgaggg tgctgcccgt ggtcatgcct gctcaccccg cagggcggcg gcggtccgca
     1441 gcgcgcggac gacggtgcgc cgggtgagct cggccttgaa ggcgttcatc gggcgggtga
     1501 cggcgggggc cagctccgcg gccgcggccc gtgcgaaggt gtcctcgtcg gcgggctgtc
     1561 ccagcagcat ctcctcggcc cggtgcgccc gccacggctt ggtcgcgacc ccgcccagcg
     1621 cgagccggac cccgcggatc accccgtcct ccagcgccag cgccaccgcg gccgaggcaa
     1681 gcgcgaactc gtaggactca cggtcgcgca ccttgaggta gagcgaccgc ctcgccatgg
     1741 gaagcgccgg cacctcgatc gcggtgatca gttcgccggg ggtgagcggg tgttcccgct
     1801 cgggtgtgtc ctccgggagc aggaagaagt catcgaccgg gatggtacgg gttcccttga
     1861 cgccctccac ctgcaccacg gcatcgagcg cgacgagcgc gaccgccatg tcggaggggt
     1921 gggtggcgat gcagtgctcg ctggtgccga ggatcgcatg gccgcgatgg acgccctcca
     1981 gcgccgaaca gccgctgccg ggaacgcgct tgttgcaggc ggattcgggg tcgcggtagt
     2041 aggagcaccg cacccgctgc atcagatttc cgcccatgga cgccatgtgc cgcagctggg
     2101 cggaggctcc cagcagcagc gactgggaca gcatcgggta ccgctccacg acacctggcg
     2161 cctcggccac ctcgctcatc cgggccagcg ccccgatgac cagtccgccg tcggcccggt
     2221 cctcgatatc ggccagcggc agccggttga tgtccaccag ccggttcgga cgcagcacgt
     2281 cgagccggag caggtcgact tccgtggtgc cgcccgcgag gaaggaactg ccggggtcat
     2341 tcgtcaccgc ggcgaccgca ccggggacgt ccgtcgcacg agtgtagctg atggcacgca
     2401 catcactgtc ctgtcttccg gtcccgcacc tcacgtatgg cggagcggat atggggatag
     2461 gccgcgcacc ggcagatgtt gccgctcatc cactcggcga tctcgcggtc ggtctcggca
     2521 tgcccttcct tcagcagcgc gacggcggac atgatctggc ccggggtgca gtacccgcac
     2581 tgcagggcgt cgtgctcaag gaacgcgcgc tgcatcgggt gcagctcatt gccctcggcg
     2641 aggccctcga tggtggtcac gtcccggccc tcacaggtga tggccagcgt cagacaggcc
     2701 agcactctgc gcccgtccac ccataccgtg cacgccccgc aggttccctg gtcacagccc
     2761 tttttggtac cggtcagtgc catgtgctca cgcagcgcgt ccagcagact cacccgtggt
     2821 tccaggtaca ggacccgcga gacgccgttg acgacgaggt ccatctgtac gccgtcgggc
     2881 ccgcggatct ccatggcgga aggcttggcg acggataggg acgcgccttt gtctgccacg
     2941 acactcacct cggagtcgat gccgtacgtc gagcgtccgt ccggtcgtcg gggcgcgcaa
     3001 ccggacgggt gaggtgctcg ggaccaggtc gcggctgccc cgaagggctc gcgccgtgcc
     3061 ccgtacggga taatgcgggg catgcggatc tcagccagag cggactatgc cgtgcgtgcc
     3121 gcgctgcacc tcgctgccgc ccgggacgcg gggccgctca aggcggaggc catcgcccac
     3181 gcccaggaca ttccgcataa atttctcgaa ggcatcctga acgacatgcg ccggggcggg
     3241 ctggtgcaca gccagcgcgg cggcaacggc ggctaccggc tggccaagcc ggcggaggcg
     3301 atcagcatcg cggacgtcat ccgtgtcgtg gacgggccgc tggtgtcggt acgcggcgtc
     3361 cgcccgccgg agttgtccta caccggcccc gccgagtccc tgctgccgct gtggatcgcg
     3421 ctgcgggcca acgtccggca gatcctcgac ggggtgtcgc tggccgatgt cgcctcggcc
     3481 gagctgccgt cccgggtgtc cgtactgacg gaggacccgg cgtcctggga gaacccctag
     3541 ggcgcatcaa gcgtggtctc gtatcccaag accgggttgt ccgccccttg aacgcccctt
     3601 gatccgcgtg cagttcacga agcattcttt ccctatcaat tcagtgggaa aactagggaa
     3661 gtggaggacg gggtgtgcac acagcacggt gttccgtccc cgcggccggc ggcgcgatcc
     3721 gtccgtccgc gcccgaccca cccgccacac ccgacaggac ggtgcaccgc gccatgccga
     3781 agaagtccgc agcaggggcc ggctccgcgc cggccggccg gctcgtcgac gaagcgctcc
     3841 ggccgcgcct cacccgggag gtcgcggacg atctggcggt ggacgccctg ctgcgcgacc
     3901 gggcgggcaa gcccccgttc gacgaggccg cgcggctgcg cgaggcgggg ctgcccgcgc
     3961 tgctgacgcc gcccggcccg gaccggcggg gcaccgactg gcgcaccgcc tgcggggtca
     4021 tccgggagat cgcggcggcc gacagctcca tcggcgaact gctgggccgg cactatgcgc
     4081 tgtcgtggag cgcccgcttc ttcagcaccc cggagcgggc cgacgcgctg gaacgccggg
     4141 cggtggcgga gcagtggctg tggggcggga gcacggacgt cccgggcgcc gaggcggcga
     4201 cggaggacgg cctcacgctc acaccggccg acggcggcta cgtactcagc ggaggcacga
     4261 ccctcgccgc gggtgtgcag gtcgccgacc ggctggtgct cggcggggtg ggtaccgaca
     4321 ccggtgactc gctgatcgtg tgtctcgacc cggagcgtcc cggtgtgacg gccgacgccg
     4381 agcacgaccg cctcggccag cggctggccg gagccggcag catcagcttc gacgacgtcc
     4441 tcgtccccgc ggacgaggtg ctcggcaccg tcccccgcga tgagcatgcc gtctccccgt
     4501 tcgccacgct cgccccgctg gcgctccggc tcgccctggt ccacgtcagc ctgggcaccg
     4561 ccgaaggcgc actggccgag gcgcgggaca gcaaccgggc ggcaccgggc cgttggccgg
     4621 tgccggggcc ggacgagagc gcgtacccgg accgtcccgg tgcggatccg tatctcctgc
     4681 tcgcgtacgg ggagctggtg acggcggctc atactgcggc ggcggtggtg gagtcggcga
     4741 ccgaggcgct ggcgcagggg ctgctcaccg ggcccgcgct gggtgtcgac gagcgcgccg
     4801 atatcgcggt cctggtggcc gcggccgagg ccaccaccgg ccgctccgcg atgcagatca
     4861 ccacgcgcat catggaactc acccaaggcg ccggttccgc cgccgacacc ctgggcttcg
     4921 accggttctg gcgcaatgcc cgcatcctga cggcgcaggc ctcccccacc caccggctcc
     4981 gcgatatcgg tgaccactat ctgaacggca cccacccgcc cttgacgctg cgcgcctgac
     5041 cgcttcagcc cgcggggtgt cgtacggccg ggcgggcgcg cggccggtgc ggcgcgatgg
     5101 tcaggacggg caggtgcggt ggcggggtaa ttcgccgggg ccgtcggcgc agcttcgaac
     5161 ggttcggcac caggggctgc tacatctcgt gtgtgcaccc cggaacgggg gagctccgtc
     5221 ggtcctgtga ggtggcgcct tgtcagaaag cagcagtgtt ccggtacagc cgggcagacg
     5281 ggcgacgttc ctccagcgga tgctgttcgg tggcgtgtac ggttcggtgc tcgccagcgc
     5341 cctggcaggc gccctgagcc acgaaggcac ggaccccggg tacgacgcgg cgtgggtgac
     5401 gctgtccgcg gtggcggcgg ccgcggcgca cggctatgcc cactccatcg cgcaccggac
     5461 cgaggacgac acccacgcca ccgcgagcgc ggtggtgtcg atgctcaccg aatggccgct
     5521 ggtggccgcg atgctgccga cgatcgccgc cctgctcggc gcctacgcga cgtggtggac
     5581 cgaggccggc gcggtcgaag tcgccctgac catcaacatg gtggcgctgt tcggctgggg
     5641 cctgtgggcg gcccgggtgg cgggccgggg gtggtgggcg tcgcttcggg tcggtggcgt
     5701 ggacgtgctg atcgggttgt tcatcgtgat cgccaacacc ctgagcaagt agccggaagg
     5761 cggcagggac cggaccggat cgcggtcctc cggtgcacgt gccgcccccg gggtcagagc
     5821 gcggatttca ccgccagcca gccggcgatg gcctgggcga tgggctggtc ggtctccagc
     5881 tggacgaagc cgaactggcc gccctgattg cattccagga accaccaggt cccgtcgggg
     5941 tcctcggcga agtcaaaggc tccataggca agttgggcgg cattcatata cgcgagcacc
     6001 gcgcgttgga cggcgtccgg cacctcggcg gcctcccagg tgccgtggtg ggtgaagcgg
     6061 ctgtccactt cctcggggtc ggccttcttg cgggcggcga agagctgatc ctcgatacac
     6121 gtcagccgga tatcggcctc cttggggaca tgccgctgga gcagggtcgg gccggccgcc
     6181 accccggaga agtccgtgtc cgggctgata cgggtggtcg gcagcaccat cggcgggtcg
     6241 ccggggtgct ttccgctgac cgacttcacc acaaggtccc ggtgggtggc ggcgaactga
     6301 cgggcggcgg acgggaagga ggtgagcagt gtggggggta cgaggaagcc gcttcgatgg
     6361 gcgatgtgca gctgccatgg cttgtagcgg gcctgtgcgg ccgcggtggg gtggttcatc
     6421 cagcgcgcgt cggtgcagct gagcatgccg tacagcgcct gctcggcctc ggccgtgatc
     6481 caggcggact gttccgcgga gcgtgctccg gggacgcccg gccggcggac ccataccgag
     6541 cgcaggctgt tcaggctcac catacgttcg cccgacttca gatatccgtg gaagtcgttg
     6601 tcggcgtact ccgccgacag ggagacccgc ccgggcagat cggcggggtc gaggcggacg
     6661 agcggaaccc cgagctcgtg cagcgtcgcg accacgatat ccgcggtcag atcttcctcg
     6721 caggtaagga ccaggacggt catcggtgct cagtcgtcga agtgggtctt ggaaccggcg
     6781 gtggaagcgg tggtgccggt ggccagcagc acggcccggc tgcaggtggc cgggcgtccg
     6841 tccggcagga cgttgagttg ccgcgtggcg tcgtagctgt acggggtgct ggtggccgac
     6901 ttcaccgccg ggcgggcgta actcaacgca aacggtcgca tgccatctcc ttcaaaaaac
     6961 ggtttccgag ccttaggcgc ggggcagagg tggaaagccc cgccttatga ctctgcacgg
     7021 aagacgcgac aatctggccg tttagttgcc tcttttgctc gtttccagcg ttccccttga
     7081 ctgaaaagcg gctaacgcgt actccctgtc ttccttatgt gtcgccgagt aggcatcggg
     7141 acccgcgcac acacgaaagc cccgcccggt cgggcggggc tgatgggtcg tcagtggcag
     7201 gtgcgctacc ccggtcccgt cccgtcgacc gcgtcccgca ccggtgtgcc gtccaggagg
     7261 gcggcgacga ggtccacggt caaccggtgc cagtggcggg caccgcggag catggtgtgt
     7321 ccgccgcgcg gcatggcgac cgtatggacc cgggccccgg cccgccgggc gcggtcggcg
     7381 aagtgccagg aggcctccgc gtcggtgatc cggtcgcgta cgtcgtgcag cagcaccagg
     7441 gtccggtccc gcagatggga gacgggctcg ccgggcgggc accacggcgc gagcgcgacc
     7501 acgccccgca ccgcacggtg cccgccgatg agcagggcgg cccggccgcc catggagtgg
     7561 ccgaccagca ccaccggtac gtccggggcg tacccggcca gttcgtcgag cgccgcgcgg
     7621 gcgtcctggg caacgtccgc ctgcggcccg ttccctcccc ggcagcggta gcgcacggag
     7681 gccagcagca cctcccgccc gcgcggggtg cgggagagcg cgcagccgaa gggccgcatc
     7741 cgcagtgcgg ggaggttgag ccgggtcggc ggggtgtggt cgtcgggccg tccgccgtgc
     7801 agcagcagca ccgctgcctg cggggtgtcc gggcggtggt gtaccaccag cggccggtgc
     7861 gggtcctgcc cgcccgtggg atccgtgggc cgttccgggc ctgtcgtcat gggcggaggt
     7921 cctcggggtc ggggtggcga cgcgccggca gcgggaagaa tccgctggta cgggcccggt
     7981 aggcggcgta tccggggcgg ccggccagct ggttctccag cagtcgcttg ccgctgccga
     8041 gcgtcagcag gtacgacatc accagcggcg agaccacggc gacggcggcg gcctgccagg
     8101 tgccgcaggc cggcaggcag gcggcggtga gccccgcgac cccgccgccc accaccgcta
     8161 tccgtcgacg ctccacagcc ggccgcctcc tcctgtcggg gcggggccgc ttccttgctg
     8221 cggcaccccg ctcaccaggg gattcggagc cggtggcggc gcggattggt ctcggggcgc
     8281 acgatcttgc cgagcggatg tgggcggtac gaggccggcc ccgccgcggc aggtgcggcg
     8341 gggccgggcc gtcagccgtg ggcggacggc tggtggtgcg cggcggtcac accccgagca
     8401 gggccagcgg cgagctggtg ggccggctgg agccgcccgg cggttctgcc gtgacgccca
     8461 cgccgtccgc gccctgtggt ccgccggtca gcagcaacgt gccgctggag ctgccggttt
     8521 cgacgagtcc ggcgggcacc atctggccgt tgcggctgta ccagagttcg tacacccgct
     8581 gaccggacag cgccggcagg ccgtggtaca ggaacgcggt ccgccccatc cgtttggagg
     8641 ccaccacggt cccgctgccg ccgcccttga gcgccgtggt gtggaaggtg gcgtccggtg
     8701 cggtcatcaa cgcgctcacc acggcggcct gttgctcggc gcggacgtta cggtcccgct
     8761 gctcctgggc gtcgtgccgg gcctggacgg cgtacccgcc ggcgaccgcg gcgcccacca
     8821 gacaggcggc ggccgccagg tagggcagcc ggtgccggaa ccgccggcgc atcggcacca
     8881 cggtcgtgcc gtggtccgcc ggcggcagct gcctgaccgt ggggagggcg gccatcaccc
     8941 gcgtacgcag ggcggccggg gggacctcgg cgaccgccag cgcgagccgg gccgcggtct
     9001 cctggagctc ccgtacctcc tgggcacagg ccgcgcaccg gtcgagatga cgggcgaact
     9061 ccgcggcctc ccggccggtc agcgcgccca gggcgtaggc gccggtcagg gtgtgcagtt
     9121 cgacggtgct catgccgata cccccaggca gtcgcggagc cggatcagcc cgtcccgcag
     9181 ccgtgtcttg accgttccca gtgccgtgcc gagcaggtcg gcggtctccc ggtaggtgta
     9241 cccgcggtag taggcgagcg tcaccgactc ccgctggagc tcggtcagtt gccccaggca
     9301 gcgccgtacc tgctcgcgct ccagccgtcg ttcgacctgc tcgctgacct cgtcgaacgc
     9361 ggtggtgtag ccatgcaccc cggcccggtg gtcgcggtcg gccgccgcct ggaccgagcg
     9421 cacccggtcc accgcgcggc ggtgcgtcag cgtcatgatc caggccatcg cgctgccctg
     9481 ccgcgggtcg aagcgggccg cggtccgcca cacctcgatg agcacctcct gcgcgacctc
     9541 ctcggactgg gccgggtccc gcaccacccg gcgcaccagg cccagcacgg tgccggccac
     9601 cgccgtgtag agactctcga acgcctgctg gtcgccgcgg gagacgcggt cgagcaggga
     9661 ctccagcgca ccggcatgcg gcgctgggga gcggtcgccg cggcgggctg cgacgggcat
     9721 ggacacctcc ggactgtgac gtggtcacag gtgattcggc gccgggtgac acctggattg
     9781 gtggggagag gattcttgct gatggcccgt cggtctccgc gcccgccccc gtctttcgcc
     9841 acgggacccg gcctcgggcg ccggcgcggg gcggtctctg cacgcaccgc gcgcgacgcc
     9901 tgtccggatc cgccgaattc ccgcgcgtcg caggccgctc cccggccggg acctgcgcaa
     9961 ggatcaccgt cggggcaccg aggcggagag aggaccgggt gtgcgggacg cggatgccgt
    10021 catcgtcggc gcgggagcgg ccgggctctc gctcgcccac cggctgtgcg ccccttcgac
    10081 gggccccggg ccgcgggtgg ttctcgtcga ggcaccgccc ggcccccgca ccccaccgga
    10141 gcggacctgg tgctactggg aagcgcccgg cggcgcgttc gacggcgcac tgaccgcctc
    10201 gtggcaacgg ctgcgcgtcc acgggcccgg cggtgcggcg acggtgggaa accccgcgcc
    10261 cctccggtac aagatgctgc gctcgcgtga tttcgaggcc ctcgtcggcg cccggctctc
    10321 cggtcgggac accgtcgtcc gggtcgaggc gaccgtggaa tccgtacggg acgttcccgg
    10381 tggagccgag gtacgggggc gcgacacggc ggggcggccg gtgctgctgc gggcccgctg
    10441 ggccttcgac tcccggccgg ccggccgcct cccgccggcc cgcaccacgc tgcggcagca
    10501 tttccgcggg tggttcgtgc acacccggcg gccggcgttc gatcccgcga cggcggatct
    10561 gatggatttc cgtaccccgc agccgggcca tgggctgtcc ttcggctatg tgctgccgct
    10621 gagcgaccgt gccgcgctgg tggagtacac ggagttctcc cgccgcatcg cggacaccgc
    10681 cgcctacgag cgggccttgc gccactacac cgaacgggtg ctgcgactgg gcgcgttcca
    10741 cgtcacgggg accgagcagg gcgcgatccc gatgaccgac gggcgcttcc cgcggcgggc
    10801 cggccgcgcg gtgttccgca tcgggacggc gggcggcgcg acccgtccgt cgaccggata
    10861 cacctttgcc gccgtgcagc ggcagagcgc gctgatcgcg gcggccctgc tggcgggccg
    10921 ggccccggtc cccccggccg cgcactcccc gtggcaccgg gcgctggatg cggtgctgct
    10981 gcgcgcgctg gacagcggcc gggtggacgg ggccgagttc ttcaccggac tgttccgcac
    11041 ggtgccgacg gcgcggctgc tgcggttcct cgacggccgc tcccggctgt gggaggacct
    11101 caccatcggc ctgcgcaccc ccgtgctgcc catgctccgc accgtcgccg agcttccgct
    11161 gctgccccgc cgtgccgcgc tctggtgacc cgtccgctcc cccgcccgcg gacgtccgcc
    11221 acgccaccgc ccctcgtacc gaccccctga ggaggatttg tgacacctcg acagcggcac
    11281 gacggggccg cacggcgcgg acgggaccgc cgggcccacc gggtgccggg gccgccgggg
    11341 cgggaccggg ccgcgcccca cgggccgcgc gtggccgtga tcggcgccgg catcgcgggc
    11401 ctcgccgccg cgacggcgct ggccgagcgg ggggcagggg tgaccctgta cgaacgggag
    11461 cggagcctcg gcggccggct ggcgggctgg ccggtgcggc tggccgacgg ctcgccggcg
    11521 accatgagcc gcggtttcca tgcgttcttc ccgcagtact acaacctgcg ggggctgctg
    11581 cgccgggtcg acccggggct ggacatgctg cggcggctgc cggactatcc gctgcaccat
    11641 cgttcgggcc tgcgggacag cttcgcgcgg gtgccgcgga ccccgccctg gagcgcgctg
    11701 ggcttcgtgg cgctcagccc caccttcggc tggcgggatc tgctgcggat ggaccccggt
    11761 gcggcgctgc cgctgctcga cgtacgggtg ccgcaggtct acgcgcggct ggaccgcgtc
    11821 agcgcccggg acttcctcgc ccggatccgg ttccccgagg ccgcgcggca cctcgcgttc
    11881 gaggtgttct cacggagctt cttcgccgat ccgggtgaac tgtcggccgc ggaactggcg
    11941 ttgatgttcc atatctactt tctcggttcc agcgaggggc tgctgttcga tgtgcccggc
    12001 gagcccttcc cacaggcgct gtgggacccc ctcggccggt acctggccgg gcacggggcg
    12061 gcgctgcgta cggacacgga ggtggtacgg gtcgaaccgg cggcggacgg cggcgggctg
    12121 tgcgtcgccg gggagcgcgc ggaggaccgc ttcgactcgg tggtcctggc cctggacccc
    12181 ggcggcctgc gccggctcgt cgccgcctcg cccctattgg gggatgccgc ctggcgggcg
    12241 cggatcgggc ggctgcggac cgcaccacct tttctggtct cccggctgtg gctggagcga
    12301 cgggtccgcg ccgaccggcc cggtttcctg ggtaccagcg gtttcggcgc gctggacaac
    12361 gtcagcgtgc tggagcgctg ggagggggag gcggcccgct ggtccgcccg taccggcggc
    12421 tcggtgctcg aactgcacgc ctacgccatg gccccggatg ccgaccgggc acgcgaacag
    12481 cgcgctctgg tgagccagtt gcacgccgtc tacccggaga cccgcggcac ccggatcgtc
    12541 gacgagcgcc acgagtggcg cgcggactgt ccgctgttcc cggtgggcgg ttacggggac
    12601 cggcccaccg tgcacacgcc cgacccgcgg gtggtggtcg cgggcgacgt ggtgcgcacc
    12661 tcgttcccgg tggcgctgat ggagcgggcc gcgacgaccg ggtttctcgc cgccaacgcg
    12721 ctgctggcgc gctggggcgt gcgcggccag accttgtgga gcgtgccggg gaaggggcgt
    12781 tcggcggtgc tgcggtgggc ggcccggcag gccggacggt gaccgggggt gcgctcggca
    12841 cccgtcggcc cggcgccgta cggcctcagc ccgggtggcg tccgctgctg cgcagttccc
    12901 agcggcgctc ggcgtatgcc aggtcgtccc gccacagccg ggccgcggcg gcgcgcatca
    12961 gcggacgcag ggccggcgcg gccgcgcgcg ccagggcgaa tcccgggcgc cgggacgtgg
    13021 cgacgatcgc ctcgatgacg gcggtgcgcg ggcgtccccg gtcgtccggg cccagcggcg
    13081 tggcgtgggt ctccaccacc gagccccgtc cttctccggc cacgatgtgc atcaccacgg
    13141 tgcgcggctc gggggcggtg aacagcgccg tgaccgggac gacagcccgg ccggcgaccc
    13201 tgaaggagac ctcgacggcg aggccttcgg cccgctcccc gtcggccggg aggccggtca
    13261 cggtgaggtc ggcgaaggag taggggtgga accacgcacc gtgccagggg tcgaggcggt
    13321 tggccacgac gtcctcgggt tcgcagcagc cggtggcggt gtggacggcg gcgacggccc
    13381 ccgccggccg tggccgggcg ggaatgacgg gctccggcaa cgggagttcg ccgcccgcct
    13441 cgtccagccg tacccagacc agcagtccgt cgtcgtgggc ggggaacggc tcccagccgg
    13501 cgaacggggc gccgtccagg gcgagtccgt gccaccggca gcggaggatg ccgccgtgca
    13561 cggggccgag cgcgaggggt gcgcccaggt gcgggcaggc accgggaccg gcgaccaggc
    13621 ggccggcggc gtcacgccag gcgacgacct cgacgccggc gacggtacgg ccgaaggcgc
    13681 ggccggcggc gatgtcgcgg gccgcgccga gcacgaacca gttgccggag ggtcgggcga
    13741 gcgcggcctt gacggcgtcg gcgatgaccg cgggtttggc gtcgggccag gtggggcgct
    13801 gttgtgccca cggctgcgga ctgcgccgga gccggagcgg gaggcgtggg tgggggcggc
    13861 gcggccggct catggggctt cctccggcac cggtaccggc acctgccgcg gcggatcgcc
    13921 cggcgacacg gcggaccgcc gagcggtgag ccgggcggtg agccgggtgg cggccacgcg
    13981 agccagaccg cccgcggcgg tggccgcccg gcgccggcgg gtgaccaccg cgcggcggtg
    14041 cagcacggcg tagccgtcgt cgcgcacagc gtcgaggatg gcgccgtaca ggacgaacgc
    14101 ggtgcggatg cacgggcgcg agggcggatc gagcagggcg aggccgggtg ccgcctcgcg
    14161 gtagacccct tgggtgaggt cggcggccgc caccagggcc gcggtgatcc gcgggtcccg
    14221 cgcgccggtg tcccggctcc agcggagcag tccgcggtcc acgccgtgtg ccgcgagcag
    14281 ctccgcgggc agatagaccc ggccccggtc gagatcctcc ccgacgtcgc gcaggaagtt
    14341 ggtgagctgg aaggcgacgc cgagggccgc ggcgtgcggc gccgcctcct cgtgtgggac
    14401 gaccgtgccg agcaccggca gcatctcaag ccccagcacc gccgccgaac cgtgcatata
    14461 gcgtcgcagg tcggcgtagg tcgggtagtc cgtcaccgtc aggtcactgc gcatcgacgc
    14521 caggaaatcg cggaagtgct ggtggtcgat gccgtaccgg gcggcggtgt gcaccaccgc
    14581 gcgcaccacg ggttcggtgg tcggggcgcc gcgcagaccg tcctccaggc actgctgcag
    14641 ggcgtcgagc gcggcggcgc ggccggcggt ggtgcggccg gcgccaggct cgtcgacgag
    14701 gtcgtcggcc cagcgggcga agccgtacag ggcgtggacg gcgggccgac gggccgcggg
    14761 cagcagccgg gtggcgagga agtaggtctt gccgtgccgg gagttgagcc ggcggcagtg
    14821 ggcgtaggcg gcgcgcagga gggggtcggt gatgcctgcg gcgtccagtt cgcgatcggt
    14881 catgccgggg tgcctctcag cgcggggcgg gacgggaggg cggcggagcg gggcgaccac
    14941 ggtccggtga tgcgggccgc ggcgagcttg ccggagagca cgacggtggg gatgccgacg
    15001 cccggggtgg tgccgcagcc cgcgagcacg gcgttctcgg tgccgcgcac gaggttgcgg
    15061 gggcggaagg ggcccgtctg cgcgaaggtg tgcgcgaggg agaacggggt tccggcggcg
    15121 agcccctgcg cggtccagtc cgccggggtg accaggtgct gctcctcgat ggcgacgccg
    15181 aagccggtga gtccccggcg ctccagtacg gcgagcaggc tgtcgcggta gcggggggcg
    15241 aggtcgtgcc aggtgcgggc gccggggccg gtctcggtgt tggggcaggg cgccagcacg
    15301 tagtgcaagt gccgccccgg cggggcgagt tgcgggtcgg aggcggtggg gcgggagatc
    15361 agcaaggagg ggtcgctcat cagccggccg gtgcgggtga gttcgtcgaa ggtgcgctcc
    15421 caggccgcgc cgaaggagag cgtgtggtgc gccaggtgcg gccaggtccg gtcggtgccg
    15481 gcatgcagga ccaccgcgga cggcgcatgg cgaaggcgca gcgggcggtg cggccgccgg
    15541 ccgaggagac ggtggacgac cggcagatcg ggggtgagca ccaccgcgtc acaggggatc
    15601 cgctcgtgcg cggtgagaac ggccgtgacc cggtcaccgg tgcggtccag ccccgtcacc
    15661 cgctgcccgt agtggaaggc ggcgccggcg tcggcggcgg catcggccat ggcctgcggc
    15721 agggcgtgca tcccgccgcg cgggaagtag accccggcga cggtgtccat gtacgcgatg
    15781 acggcgtagg cggccagggc gcgcgcgggc ggcacaccgg cgtacagcgc ctggaaggag
    15841 aagacccggc gcagccgcgg gtcgggcaga aagcggccga tccgggcgtc gaggcggccg
    15901 aaccccccga gggcggcgag ccgtaccagg tccgggtgca gcagctggag cggcgagtcg
    15961 aagttggcgt cgatgaagcg gtgccgctgg agggcgtaca tctgctggag ccagcggcgc
    16021 agccggcggt agccgtgcgc cgccccggcg ccggcgaacc gttcgatctc ggcctccatg
    16081 gccccggggt ccgtgtgcac cgccagttcg ctgccgtcgg cgaaccgggc gcggtaggcc
    16141 gggtgcagtg cccgcagttc cagccggtcg gtgaggcgtt cgccgaccgc ggcgaacgcc
    16201 tcgtcgagga ggtccggcat ggtcagcacg gtcggtccgg tgtcgaggtg gtagccgttg
    16261 cgctcgatcc gcccggcccg gccaccgggc cgctcctcgc actccacgac cgtcacccga
    16321 cgcccggcgc cgagcagatg cagcgcggcg gacagcccgg agagcccggc accgaccacc
    16381 accacgtggt cggtgcggcc cggaacggct ctcatgcctg gttcctttcg gtacggcggt
    16441 cagacggacc ggaagacgag tgcggcgttc tggccgccga agccgaagga cgtactggcg
    16501 gcggcggaca gcggcgtgct gcgcggggcc ttggccacga tgtccagatc gatgtcgagg
    16561 tcgcggtcct cgtggttggc ggtgggcggg atggtggact cctgcaggct catgacggtg
    16621 accgccgctt cgatggcgcc ggccgctccg atggcgtggc cgagggcgcc cttgagggag
    16681 gtgacggccg ggggcgcggg gaagacggcg tgcagggccc tggcctcggc caggtcgttc
    16741 aggcgggttc cggtgccgtg cgcattgaca tggtcgatgt ctccgggcgt caggccggcg
    16801 tccgccaggg ccgcggtgag ggccgccgcg gcgccccggc cttccgggtc gggggcggcg
    16861 tagtggtagg cgtcgcaggt cgcgccgtag ccggccagct gtgcgcgcgg gcgggcaccg
    16921 cgggcccggg cgtggtcggg gcgttccagc accaggacgg cggcgccttc ggagaggacg
    16981 aagccgtcgc ggccggcgtc gaacgggcgg caggcgcccg cggggtcggc cacccgtggg
    17041 gagagggcgc ccatgcggtg gaagcaggcg gcggggatgg ggtggcgggc ggactccgcg
    17101 ccaccggcca ggacgatgtc gcaggtcccg gcgcgcagca gatcgcgggc gacgccgagg
    17161 gcgctgctgc ccgaggcaca ggcggtggag accgcgaagt tggggccggt ggccgtcagg
    17221 tcgagggcga tttcggcggc ggccatgttg ggcacgctgc gggtgacggc gagcggcgag
    17281 atgtccagcg ggcggccggc cgcgagcttc gcgaactcgc cgacatagcg ctccatgctg
    17341 gccgttcccg tcccgatgac cacgccgacg cgggcggcgt cccagtcggc gggggcgagg
    17401 ccggcgtcgg cgacggcgtg ccgggcggcg aggagggcca tggcgacgaa gcggtccagc
    17461 cgccaggcgg ctttccggcc gaccaggcgc gcggtgtcga agtccggcac ctggcaggag
    17521 atgtccaccg gcagtcccgc cagccccggg tcccgggcgg cggtggaccg gccggtgagc
    17581 agcccctccc aggtggcccg ggcgccgata ccggccgggc tgacgacgcc caggccggtg
    17641 acggcgacct cgcggcaggg cccgggcatc agctggtgct gttcggtgcg gccgtcaggg
    17701 cctggtcggc ctcgttccgg tccatgagct ccgccagccc ggcgatggtc gtctggaggg
    17761 gtacgtcgtc cagggagatg ccggtccgtt cctggagcat caggcccatc tcgaccaggg
    17821 cgagggaatc caggcccagt tcctcgaagg tgcgctcggg ggtgacgtcg gccgggtcga
    17881 ggtcgaaggt ttcggtgagg gtggtggtga tcagctcggt actggtgggc acggaggact
    17941 ccttcggtgg agggggtggt gccggccgcg ggctccgggc gcggtgtcgt ccgggcgcgg
    18001 gacgccgttg ggaacagccc tcgcgcgtcc gtgcgcgggc gcgggggcgc gccgggccgt
    18061 gcgggtgcgg acgggggtgc ggcatcgcgg ctccagacag gcgggcggca ccgggggcgg
    18121 tgcgcagtcg gtcgcgcgcc ttccactgtc gccgaccgtg tccttcggca cctggcatga
    18181 aggcacctcc gaacgagtgg cttatcgctc cggggcgccg ggggttcgtc cctggtccgc
    18241 ggccagggcg cgcggagccg gcggggtggc gcggcgggcg tcatgggggc ggggcggccg
    18301 gccgagccag cgggcggccg ccgcggcggt gagcagggtg acggctccgg cgacgacggc
    18361 ggtgagggtc atcgcgtcgg tgaaggcgct gcgggcggcg gacagcacgc cggcgcgcag
    18421 cggtgcggga aggcgccgcg cctgttcggg gacggacagc atgctgtgtt cggccgccgc
    18481 ggtcaccagc gtgggggcgt gcagaccggt cagggacgta ctgagccggg aggtgaagac
    18541 ggccgcgagc agggagccct ggaccgccac gccgagggcg gagccgacct ggcgggtggc
    18601 gtcgttgatg gccgatccga gtccggcccg ttcggtggcg accgacccca tcaccgactc
    18661 ggtggccgct gccgcgacca gtcccgcgcc gacgccggcg accagctgga agaccgcgca
    18721 gtgcgggtag ccggagtcgg gggtggtggt cgccaggacg gcgaagccgg ccgtgacgag
    18781 ggtcagcccg gcgacgacgg ggatccggcc gcccagccgg gtccgcagcg gcacggcgca
    18841 caccgcgccg agggccagtc cgcccggcag cggcagcgtc cgcagaccgg cctgccaggg
    18901 gctgaagccc agcaccccct ggagatagag ggtcagcacg aacagcgccc cgaacatggc
    18961 gaaggacatc aacgccaggg ccgctgccgc cactccgatg cccggcaccc gcagcaggta
    19021 cagcggcagc atcggggcgg gcgtacgcag ctgccgggcg acgaaggcgg ccagcagcag
    19081 ggcggcggcg gcgaatccgg tcagcgccgc cgggctggtc cagccgcggt gcgggctctc
    19141 ggtgatggcc cacaccagcg ccagcagccc cgcggcggac agcgcggcac cgggcacgtc
    19201 gaagccggcg cgctgcaccg tacgggactc gggcaccagc gccagggcga ggacgacgat
    19261 gacgccggcc aggggcaggt tgatccagaa ggcggcgcgc caggagtagt gctccaccag
    19321 ccagccgccg atgaccggac cgcacagtcc ccccatcccg ccgaccgcgg cccatgcggc
    19381 gatcgcccgg ctgcgcagcc ggggttcggg aaacaggtgg tggaggaccg ccagggtggc
    19441 cggcatcagc agcgcggccc cggcccccat gacgcagcgc gcggcgatca cctgccacgg
    19501 gtgtccggcc agcgcgccgc ccagcgaggc gcccgcgcac accgtcactc cgcagacgaa
    19561 ggagcgccgc cggccccagg cgtcggtgaa ggcgcccacg gccagcaccg taccgcccag
    19621 gaccagggcg taaccgtcca cgatccactg cacctgcgcg gtggaggtgt cgaggtcgcc
    19681 ctggaggtcg gggacggcga cattgaggac ggtcagatcc aggccgagca tgaacaggcc
    19741 gaggcacacc acggcggccg cccccgcacg ccgggcgggc ccggccggcc cagtggtcgt
    19801 catgccgtcg ccacggggcg gttgatgacg gtgccgagga cgtcggtgag gtggccgacc
    19861 agttcctttg tcgccgtgtg cagatagctg tgcccgccgg ggaagagctg tgcggaggcg
    19921 ggggtggtga ccaggtcgtt ccaggcctgg agctgccgca gaccggtgac ggggtcgtgc
    19981 tcgccgccgt agagggccag gggcaccggg agcggcggtt ccggatggtg ccggtagtgc
    20041 aggagcagca gcaggtcggc cagtagcggg gtgcaggccg cggccatcag gcgggcatcg
    20101 gcgagcagtt gctcggggat cgggccgacg agttcacgaa ggcccgccag accggccgtc
    20161 aggcgcggcg ggaggtccgc ggtgtaggcg tcgagatgcg gcgccgacag cgaggacacc
    20221 gccagcagcg cgggcgggcg gccgtgggtg cgccgcagat ggcgggttgc ctcgtaggcc
    20281 agtagcgcgc ccgcgctgtg gccgaagacc gcgaacggcc gggggtcggt ccagtcgtcg
    20341 agcacggcgg cgagccgggc gctcagatac gcgggatcgg tcagcgacgg ttccccggcg
    20401 cgggtgcccc ggccgggcag cgccacggaa cacagctcga tccagggcgg cagcaggggc
    20461 gcccagcgca gatagcagtc cgggccggcg ccggcgggcg gtacggcgta cagacgcagc
    20521 gcggcctgcg gacgggcggc cagcacgacg cgttccggca ccgccgtcgc cgcggccggc
    20581 accgacgtcg actcctgtgt gaaaccgaca cccatgactc acgcccttcg cctcgcgctc
    20641 caccggtggg ccgctccggc cccgcgccgc cggccgcccc ggcggagccg cgcgcggccg
    20701 tgctgccggg caccccgccc gccggccgac gggcccgtgg ccccggaccg gtgcccacgc
    20761 cgaccctgcc ctcccccgcc cgctcactcc acacaccacg caaggcgccg gccccgtctg
    20821 acaccaacgg cggcagccgc ccgccgtcag cgggccccgg tccaggcgcg cggggcacct
    20881 cgcaccgggc cgccgtgcgc cgtccgttca gcggccgccg ccccctaccc ctagggggtg
    20941 tctcttcgat ctccgtggat cagcctgcgg cgtctggtgc cgtgcatcgc gaggcggagc
    21001 atctcccgcg gactgggtgt ccgtgggtga tgtgacaacg cagcgtgggg gcacccccag
    21061 cgttagctgg gggagtgcgg tgcctggggg cacctcccag cgttagctgg gggagcgtcg
    21121 caggcccacg gagatcggag agacaccccc tagtacttca gagctaggcc ggaagtgcgc
    21181 tccacggcgg gacgtggacc aaccggtgcg cttcgtagct tcctcccgga agccacgacc
    21241 ggcttccgtg acggaaggac cgatcctcat ggcgtcccgc ccgcgcagcg gccgactgct
    21301 gcgcaccctg ctcgccgccc tcgtggccgc ctcggtggcc gtgcccgtgt ccggcgcggc
    21361 ccgccccgcg gccgtcccgg cgcccgcgcc ggtggccctc gccccgttgc gggccgccgg
    21421 gcccggcgcg ctcgccgagc ggtatgccgt caaccgtgcc ggcatccgcg cggcggcccg
    21481 gatggccgac ggccacggtg accgggcacg ggcccgtgca ctgcgccgga tggccggccc
    21541 ggcgcggcag ttcctctcct tcgacgggcg gggcgggggc cgtaccgccg aggtcttcgg
    21601 cgatctggcg cgggccgagc ggatcgccgt cctcgtgccg ggctcggaca ccaacctcga
    21661 cacctatgca cggttccagg ccggcgcgac ggcgctccgg cggacgctgg acgaccggtc
    21721 cgccgtggtc gcctggctcg ggtacgagac gccgggcacg gtgagccccg aggtggtcac
    21781 gcccggccgc gcggcatcgg ccgccccgca actacgttcg ttcctcggcg agatggtggc
    21841 gctgcggccc tcggcccgga tctccgtgct gtgtcactcc tacggttcgg tggtctgcgg
    21901 ccgcgccgcg ccggggctga aggtggccaa cctcgtgctg tacggcagcc ccggcgccgg
    21961 ggtcgacagc gcttcggccc tgcacacctg ggcgaccgta tgggccggcc ggggggaggg
    22021 cgactggatc gccgaggtgc cgcacggtca gctggacctc ccgttcacca cgctcgggct
    22081 gggcgccgat ccggtctcgg acgccttcgg ggcccgggtc ttcgcagcgg gcgccggcgg
    22141 ccacagcgac tatctcgcgc ccggctccgt cgccctgcgg aacatcgccc ggatcgtctc
    22201 cggccgggct ccgtccgggg agcgtcgtga tgcgtgagct cgcccggcgg atcgccgccg
    22261 ctacgccaga cggccgggac cgtggcgtcg acgccctgcg ggcgctcgcc atcctgggtg
    22321 tggtgctcgg gcactggctg gtgaccgccc tggtcaccga cagcggcgcc gtgcacggcg
    22381 ccagcccgct gcactccctg ccgcaactca cccccgtctc ctgggtcttc cagacgctgg
    22441 cggtcttctt tctcgtcggt ggccggatgg cggcgacgag tcatgccgcg gcccgcgccc
    22501 ggggcgagag ttacgggcgg tggctcggcg cccggacggc ccggctgttc cggccggtgg
    22561 cggccgtcgt gctgctctgg tgcgtggtgc tggtcgccct gctcgcctcc ggggccggcc
    22621 tggagaccgt tcgcaccctg ggcacactgg cgtggtcccc cctctggttc ctgctggtct
    22681 tcatcgcgct gacggcggcg accccgctgg tcgccgggct gcacccgctg tggccgctgg
    22741 ccgtcgtcct ccacatcgac ctgctccgct tcggcttggg cggtccggag tggctcggct
    22801 ggctcaatgt gccggcgggc tggctggttc cgtactgcct gggcgcggcc tgggcccgcg
    22861 gccggctggg cggccggacg accggctgga tgctgctgct cggtggcggc gccgccaccg
    22921 ccggactcgt cggctgggcc gggtatccgg ccgccatggt cggggtgccc ggcgccggga
    22981 tatccaatct caacccgccc accctcgcgg ccgtcacctt cggcctggcc cagtgcgggg
    23041 cggccctgct gctgctcggt ccgctgcggc gggtcctcca acgccccctg gtctgggcgc
    23101 cggtggcgct gctgaacctg tcggcgatga cggtcttcct gtggcaccag accgcgatga
    23161 tggcggtcac cgcgctcggc ctgctcgcgg gccggcccct ccccggcctg cacaccgccc
    23221 ccgacggtgt ctcgtgggtg ctggcccggc tggcctggct gccggtgttc ggggtggcgc
    23281 tgctggtgtg cggagccgcg ttccgcgggt acgagcaggg ccgggcgggg cggcgcggcc
    23341 gcgcccgggc cgtaccggag cggcgccccg ctctgtcggc ggcggggagg cgtgtctagg
    23401 gtggttcaca tgatcacggg gggcgtgaag ggcggggaac cgcggtggcg gacggcgctg
    23461 ttggcggtgc cccgtacgct gcgcgacgat ctgtggacgg cggcggccga tccgctgccg
    23521 aagttgagca ggccccgcct gctggctcgg ctgccgcatg ccgtgatcgg tgtgctcgcc
    23581 tatgcgacag gcgtcctcac cacggacttc ctcacccatg tctacgggct ggtgccgggc
    23641 ctggcgctgc tgctcgcgct gtgccagtcg gccgcgctgc tcgcggccat gttccgtccg
    23701 ataccggcct ggtggatgtc gacggccgcg atggccgtcg gggccgtcgc cgctcggagc
    23761 gatctcccct gggaggcggg cttcccctgg accgaacccg gcatcctcgc gcaggccgcg
    23821 acggcgttcc tgctggcgct gcgggtacgc ccccgggtcg cggccgaggc gctggggatc
    23881 aacgtcctgg ccgggctggg ctgcctgatg ttcctcggcc aggggcagca cgaaaatctg
    23941 acgcaggcgg tttcgctcct ggtcatcgcg acggtcctgg gcgccgcact gcgcggccgc
    24001 cgggtggccc gtagccagct cgtcgcgcag gaggagctca ccgccgagga gcgggcccgg
    24061 cgcaccctgc tggaggagcg caaccggatc gcccgggagc tgcacgacgt ggtcgcccac
    24121 cacatgtccg tgatctccat ccaggcacag gtcgcgccgc atctcgtcac ggaccccacc
    24181 gacgagctga aggagaacct cgcgggcatc cgcgcgaatg ccgtcgacgc gctgaccgaa
    24241 ctccggcggg tgcttggcgt cttgcgctcc gaggacccct cgggggaagg cgtacggcac
    24301 gccccgcagc ccaccctcgg ccggctggat gagctgatcg ccaatgtgac ggcggccggc
    24361 ctcaccgtca ccaccgaaac caccggcgag ccgcatgcgc tgtcgccggg ggccgagctg
    24421 tccgcgttcc gcatcgtcca ggaggcgctg agcaacgcga tgcggcacgc gcccggcgct
    24481 acggtgcagg tgcagctcgg atacgggtcc gccggtctca ccctccgggt caccaacacc
    24541 gcgccggacg gcccggcccc gccctccccc ggctccggcc acggactgct gggcatgcgc
    24601 gaacgcacgg ccatgctcgg cggcgaactg gccgccggcc ggaccccgga cggcggctac
    24661 gaagtgaccg ccctgctgcc cgcccctgcg agaacaccgg ccgacgccgg cgaggacacc
    24721 ccatgacgac catccgtgtg ctgatcgccg acgaccagat gatggtccgc cagggattca
    24781 ccgtgctgct caacgccgaa ccgggcatcg aggtcgtcgg ccaggccgtg gacggcatcg
    24841 acgccgtcgc caagaccgcc gaactcgccc cggacgtcgt cct
//
