LOCUS       NZ_FZPH01000008        20948 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Asanoa hainanensis strain CGMCC 4.5593, whole genome shotgun
            sequence.
ACCESSION   NZ_FZPH01000008
VERSION     NZ_FZPH01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Asanoa hainanensis
  ORGANISM  Asanoa hainanensis
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Asanoa.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900188485.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 02:44:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,204
            CDSs (total)                      :: 8,124
            Genes (coding)                    :: 7,995
            CDSs (with protein)               :: 7,995
            Genes (RNA)                       :: 80
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 20 of 129
            Pseudo Genes (incomplete)         :: 110 of 129
            Pseudo Genes (internal stop)      :: 8 of 129
            Pseudo Genes (multiple problems)  :: 8 of 129
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:45:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 268062
            Orig. end                         :: 289010
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FZPH01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20948
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20948
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20948
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10948](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10948)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            659..1414
                     /gene="hisF"
                     /locus_tag="CHC05_RS21330"
                     /old_locus_tag="SAMN05421812_108253"
     CDS             659..1414
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019900882.1"
                     /locus_tag="CHC05_RS21330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108253"
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="WP_089251538.1"
                     /transl_table=11
                     /translation="MSVAVRVIPCLDVDAGRVVKGVNFVDLRDAGDPVELAAAYDAAGA
                     DELTFLDVTASSDDRGTMLDVVRRTAESVFIPLTVGGGVRSVSDVDILLRAGADKVGVN
                     TAAIARPELVSEIAQRFGNQVLVLSLDVRREPGRGFEVTTHGGRKGTGLDAVEWARRVA
                     DLGAGEILLNSMDADGTKAGFDLELIRAVRAAVDIPVIASGGAGTTAHFPPAVEAGADA
                     VLAASVFHFGELRIADVKTALREAGNPVR"
     gene            1464..2705
                     /locus_tag="CHC05_RS21335"
                     /old_locus_tag="SAMN05421812_108254"
     CDS             1464..2705
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="CHC05_RS21335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108254"
                     /product="MFS transporter"
                     /protein_id="WP_179266303.1"
                     /transl_table=11
                     /translation="MRLRENLVPPAGLPRAYALVSLIFGIGVGTFITGSTVFFTRVVGL
                     QPHEIGIGLSAAAGAVLVCSLPLSSLADRFGPRRAWLFGVAGSAAGFLLWPLARGFFTF
                     LAMIVFFELVNGVAQAGRNVYLIEAVDPETRVRTQAFARSWLNIGWSVGAGLAALALAI
                     DTRAAYLALPLANAAVLLANLVLIARLPAGPAGRARTRTPGERHVFADRHFLAVTVLCA
                     VLLAYGTVELQVAPLWLLTHTDAPKWWIGVLTLVNTVMATTLQVAMTRGAHTLDGAARA
                     LRLGGLAAALGCPVFYLAGATSGVVTMVVFVVAAVLFTLSEMWQSAGSWTLAAELPPPG
                     RRGEYFGAFRMGNSAIEMVAPASLIALAVTTGGWGWLLIGGVFLAAGLSAVPLVRWAGR
                     HRAAAPAEPEPALT"
     gene            2781..3323
                     /locus_tag="CHC05_RS21340"
                     /old_locus_tag="SAMN05421812_108255"
     CDS             2781..3323
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR02983.1"
                     /locus_tag="CHC05_RS21340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108255"
                     /product="SigE family RNA polymerase sigma factor"
                     /protein_id="WP_218824615.1"
                     /transl_table=11
                     /translation="MSIISRQEAPVSTDPPSVEAEFTAFVSANYGRLLHVADLLIGDAG
                     RAEELLQTVLTRTYLRWSRVRQDNPLGYVRTGLANARTDWLRRGLGRERPTAAVPVSVL
                     APDPSEQVVGRDAVQRALAVLTRRERAVVVLRFYEDLSEAEIARTLDIAPGTVKSTCAR
                     ALVKLRVSPELQEGNRS"
     gene            3320..4435
                     /locus_tag="CHC05_RS21345"
                     /old_locus_tag="SAMN05421812_108256"
     CDS             3320..4435
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHC05_RS21345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05421812_108256"
                     /product="hypothetical protein"
                     /protein_id="WP_089251542.1"
                     /transl_table=11
                     /translation="MNTIEDLRAALDYPDPPAKPDTRAIIARGRRRRVVRRAAVGGGLA
                     VVVAGVVAVNALGGTPAPPPVLVGSAPDPALVTASTTAVAEAPERFDPLTRTLHVGWIP
                     AGLTGQGAEISVTQQSFGGRDKEFADGGRDYGLSVMLLAKGRPPTDFMGGLGMPRESVE
                     SETDDVNGKPAVCLSDPEVRGSCAALQWEYAPGAWARVGYSGSAGPTPEAAAAVARRVA
                     ESVRFTAGEPVRLPFTIGGSTAELPAARTQVSIFAPAYQQEGGEVWNADLCLAPSPRDV
                     ERSVGDTRQLCLGASKAVGTGARLPDDPEPNATVDGHDARIVDMQLIVWNVSGIRVDTT
                     YSDWDVNPRYAYEDLRVAEDPADPADWPVSR"
     gene            complement(4425..4847)
                     /locus_tag="CHC05_RS21350"
                     /old_locus_tag="SAMN05421812_108257"
     CDS             complement(4425..4847)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018821166.1"
                     /locus_tag="CHC05_RS21350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108257"
                     /product="hypothetical protein"
                     /protein_id="WP_089251544.1"
                     /transl_table=11
                     /translation="MGQDGWRRSDAWIFVAVVMANGAGRHMRSATTRRPEGVRLADVLS
                     MADHLRQLLPGRREVEEAVRRLTGAGLITVVDGWFRVTAAGGTLWRNRRSGVGAVDTVY
                     TQLLRRPIPDDSDWTLDDADHAAAILEYAGRAETTD"
     misc_feature    complement(4866..4883)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.47"
                     /tool="antismash"
     gene            complement(4930..5595)
                     /locus_tag="CHC05_RS21355"
                     /old_locus_tag="SAMN05421812_108258"
     CDS             complement(4930..5595)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072133.1"
                     /locus_tag="CHC05_RS21355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108258"
                     /product="hypothetical protein"
                     /protein_id="WP_245871105.1"
                     /transl_table=11
                     /translation="MASESNHPMALRDRLPRRLTQLYLGLLLYGASMALQIEATLGLDP
                     WDVFHQGLAEKTGLSFGTIVIIVGAAVLLLWIPLRQKPGIGTVSNIVIIGLAVDASLAL
                     LPTPDSLAVRIPFLILGIVLNGVAGGLYIGARLGPGPRDGLMTGWVGRKPGRSIRLTRT
                     VIEVAVLGAGVLLGGTVGIGTVAYALLIGPLNHVFIPLFTVRPSPPRIGGQPIAEPAA"
     misc_feature    complement(5242..5244)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5656..7110
                     /locus_tag="CHC05_RS21360"
                     /old_locus_tag="SAMN05421812_108259"
     CDS             5656..7110
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (145-462). E-value:
                     8.2e-30. Score: 96.0. Matches aSDomain:
                     nrpspksdomains_CHC05_RS21360_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018730768.1"
                     /locus_tag="CHC05_RS21360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108259"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_089251546.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.3e-29, bitscore:
                     96.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSLVRGSQLARLLGHWHALPGRRRNPDYAALAGAVRGLLADGRL
                     PLGIRLPAERELAEALKVSRTTVTAAYRELRDSGHLTSRRGAGSWTTLPGGHRVASTGL
                     WTPLNDLGMIDLGCAALAAPPELIPAARAAADELPRYLGDAGYHPTGLVELREAVARGF
                     TDRGLPTSPDQIMVTSGTQQALDLVLRLTVQAGNGVLMESPTYPNALAALSARRARITT
                     HGLDPAAGWDGELLLGALRQSTPRLAYVIPEFHNPTGHLMPADLRERLVAAAHSTGTDL
                     VVDESFVDLPLDGVEVPPPVAMFDRHSRVITIGGMSKPYWGGLRIGWVRASAPTVQRLA
                     ALRVGVDMSSPVLDQLVAAQLLDRADTIVPARRLQLATQRDALLEALAEHLPEWRVQIP
                     HGGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPYTLPAGDLIDA
                     VKRIATVRYDLDHAPHPGWRKPVVIA"
     aSDomain        6091..7041
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CHC05_RS21360_Aminotran_1_2.1"
                     /evalue="8.20E-30"
                     /label="CHC05_RS21360_Aminotran_1_2.1"
                     /locus_tag="CHC05_RS21360"
                     /protein_end="462"
                     /protein_start="145"
                     /score="96.0"
                     /tool="antismash"
                     /translation="GYHPTGLVELREAVARGFTDRGLPTSPDQIMVTSGTQQALDLVLR
                     LTVQAGNGVLMESPTYPNALAALSARRARITTHGLDPAAGWDGELLLGALRQSTPRLAY
                     VIPEFHNPTGHLMPADLRERLVAAAHSTGTDLVVDESFVDLPLDGVEVPPPVAMFDRHS
                     RVITIGGMSKPYWGGLRIGWVRASAPTVQRLAALRVGVDMSSPVLDQLVAAQLLDRADT
                     IVPARRLQLATQRDALLEALAEHLPEWRVQIPHGGVTLWAELDGPISSALARAAEEVGV
                     RLAPGPRFGLDGTLERFLRLPYTLPAGDLIDAVKRI"
     gene            complement(8039..9859)
                     /locus_tag="CHC05_RS21370"
                     /old_locus_tag="SAMN05421812_108260"
     CDS             complement(8039..9859)
                     /NRPS_PKS="Domain: AMP-binding (14-469). E-value: 3.1e-89.
                     Score: 291.3. Matches aSDomain:
                     nrpspksdomains_CHC05_RS21370_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475807.1"
                     /locus_tag="CHC05_RS21370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108260"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_089251548.1"
                     /sec_met_domain="AMP-binding (E-value: 8.6e-90, bitscore:
                     295.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLDVPYRSIPDMFLQRVAASPDARAFGYPGASGPQWMTWQQVGE
                     RARSLAAGLHGLGVGAEERVAIIANTRLEWVIADLGIMCAGAATTTVYPTTEPEDATFI
                     IADSGSKVVVAENAMQAGKLAGANLPAVTHVVLIDGDADPAASPPQLTMADLEKQGAAA
                     LAGDPELIERLVAEIAPDSLATLIYTSGTTGRPKGVELLHAGWCWEAVAQADLGILRAD
                     DLQYLWLPLSHSFGKTLLCGIIHVGLPTYVDGRIDVLVDNLGVVKPTLMCGAPRIFEKV
                     YNKAITNATSEGGAKAKIFGWAVATGKRKVQLEQADQPVPAGLRMQYAIATKLVFSKLQ
                     ARLGGNIRTLVSGAAPLSVDISEFFAAAGLPISEGYGLTETSAGNFVNRPGGLRIGTVG
                     QPLGDLECKIDSDGEVLLRGTPVMRGYHNLPEETAAAFTEDGFFRTGDIGEISEDRFLK
                     ITDRKKDLVKTSGGKYIAPSHIEGLFKAICPYTSQAIVVGQARNFCTMLITLDPDAIAA
                     WAASGDLAGKPYAEIVASPQAHEMVEGYVTELNAKLNRWETIKKFTILPRDLTIEDGEV
                     TPSMKVKRRGVEANFADEINKMYEGTLAEI"
     aSDomain        complement(8453..9817)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CHC05_RS21370_AMP-binding.1"
                     /evalue="3.10E-89"
                     /label="CHC05_RS21370_AMP-binding.1"
                     /locus_tag="CHC05_RS21370"
                     /protein_end="469"
                     /protein_start="14"
                     /score="291.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LQRVAASPDARAFGYPGASGPQWMTWQQVGERARSLAAGLHGLGV
                     GAEERVAIIANTRLEWVIADLGIMCAGAATTTVYPTTEPEDATFIIADSGSKVVVAENA
                     MQAGKLAGANLPAVTHVVLIDGDADPAASPPQLTMADLEKQGAAALAGDPELIERLVAE
                     IAPDSLATLIYTSGTTGRPKGVELLHAGWCWEAVAQADLGILRADDLQYLWLPLSHSFG
                     KTLLCGIIHVGLPTYVDGRIDVLVDNLGVVKPTLMCGAPRIFEKVYNKAITNATSEGGA
                     KAKIFGWAVATGKRKVQLEQADQPVPAGLRMQYAIATKLVFSKLQARLGGNIRTLVSGA
                     APLSVDISEFFAAAGLPISEGYGLTETSAGNFVNRPGGLRIGTVGQPLGDLECKIDSDG
                     EVLLRGTPVMRGYHNLPEETAAAFTEDGFFRTGDIGEISEDRFLKITDRKKDLVKT"
     CDS_motif       complement(8549..8623)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHC05_RS21370_0002"
                     /evalue="1.60E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="CHC05_RS21370"
                     /protein_end="437"
                     /protein_start="412"
                     /score="23.7"
                     /tool="antismash"
                     /translation="GEVLLRGTPVMRGYHNLPEETAAAF"
     CDS_motif       complement(9251..9310)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHC05_RS21370_0001"
                     /evalue="2.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="CHC05_RS21370"
                     /protein_end="203"
                     /protein_start="183"
                     /score="23.3"
                     /tool="antismash"
                     /translation="ATLIYTSGTTGRPKGVELLH"
     misc_feature    9886..9901
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     misc_feature    9891..9911
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.48"
                     /tool="antismash"
     gene            complement(10001..10948)
                     /locus_tag="CHC05_RS21375"
                     /old_locus_tag="SAMN05421812_108261"
     CDS             complement(10001..10948)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287567.1"
                     /locus_tag="CHC05_RS21375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108261"
                     /product="hypothetical protein"
                     /protein_id="WP_089251550.1"
                     /sec_met_domain="T1TS (E-value: 3.1e-63, bitscore: 208.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTFAATALTPPPYESLVHPAVAEVAAHSADWADAFGLVPSPAAR
                     ERLARADAASLAARACPEVSLSAVKLLADLITWLFAFDDRCDEDELGANPARLAPALAP
                     LLEVVDRFGTTAHAGYQPAGPTAAALHDLCRRVRALGRPGGLLKFAAAFREYLFALLWE
                     ATNRQLHRVPRFAEYVQMRRHTGAVLPSFALTDLATDGLAATVDRVDPRVVRLDLLAAD
                     LVCWCNDVFSYGKERLRDGHNLATVIAYELTWPERAALTEAAARYNAGLAAYGALEAEV
                     LADADGRLSRMLQSRRRWLRGTYDWSLGALRYHP"
     gene            complement(11020..11649)
                     /locus_tag="CHC05_RS21380"
                     /old_locus_tag="SAMN05421812_108262"
     CDS             complement(11020..11649)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183502.1"
                     /locus_tag="CHC05_RS21380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108262"
                     /product="TIGR03085 family metal-binding protein"
                     /protein_id="WP_089251552.1"
                     /transl_table=11
                     /translation="MSRFVRSERRKLADLFSTVGPDAPTMCTGWVARDLAAHLVIRERR
                     PDASLGMFIPPLRSHARNMLRSFASRPYPDLVELVRNPPLWSPVSNPLVEGMTNGLEFF
                     VHHEDVRRAQAGWQPRDLPKEDQAALWKSASLIARLRLRKFPAALLVQAPGFGEVTTGA
                     GGEPLRLVGAPGELAYFLSGRQRATRVQIDGPPELADRLRTSPLKI"
     misc_feature    complement(11690..11705)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.52"
                     /tool="antismash"
     gene            11814..13682
                     /locus_tag="CHC05_RS21385"
                     /old_locus_tag="SAMN05421812_108263"
     CDS             11814..13682
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462943.1"
                     /locus_tag="CHC05_RS21385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108263"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_245871107.1"
                     /transl_table=11
                     /translation="MASVTSRDVLARGFRVLGRAIKDEPRIFAFAVGGSVLFGGLVVGS
                     AYVIGHIVGKIIVPAIEDGAVDNALLWLGALAVLAISVLRVVGIFGRRLGAGYMQFRLQ
                     ARYRRLVTGRYLDLPLSWHHRHATGTLLSNANSDVEAAWFPIAPLPFAVGTLVMLLGAV
                     GSLFLTDWVLALVGLATFAGLFLINVFYSRRMAPRQARAQLMRGEVSAIAHESFDGALV
                     VKTMGREGQETDRFAGQARELRDALISVGRLRGLFDPLMETLPSLGTLAVLIVGTFRLR
                     AGDISVTDLVSIAFLFTVLAFPVRAIGWVLAELPRSVAGWDRLQHVLTATGEMRYGTIS
                     PEKSDSPARLAFDGVDYAYPTGADTDDMAAAATQDEHGPTVLHDISLVVPEGRTVALVG
                     PTGSGKSTIASLAVRLVDPATGTISIDGHDLPDLTAAALADNAALVAQIPFIFDDSVRA
                     NVALDRPGIDDDAIWAALRLAQADEFIARLPEGLDTMVGERGTSLSGGQRQRLTLARAL
                     AGRPRLLVLDDATSAVDPRVEAAILAALRGGEQPTSIMVVAYRRATIALADEVVYIEHG
                     RVVAAGTHSELLASTPGYADLVTAYERAEAEREREHAYEDEGAVTA"
     gene            13763..15493
                     /locus_tag="CHC05_RS21390"
                     /old_locus_tag="SAMN05421812_108264"
     CDS             13763..15493
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018824279.1"
                     /locus_tag="CHC05_RS21390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108264"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_245871135.1"
                     /transl_table=11
                     /translation="MRRGLSLSPELRTGLAGTLFFAIISMVGRAAVPVAIQQAIDKGIA
                     GPGGLDVGFVGTVAAITAGVLAVTTLCGYLMMRRLFTVSETALANVRVRTFRHIHDLSM
                     LHQQSERRGSLVSRVTSDIDQITQFLQWGGVILIISAGQLLVTAGVMAFYSWQLTLVVL
                     VAFAPAVFVIRAFQKRLAGAYGLVRQRMGALLAAVSESVVGAPVIRAYGVSERTRTRLN
                     TAIDGHKTSQMRALRTSVIGFSSGEIAAGLATAAVVVVGVQLGIGGTLTIGQLTAYLFL
                     VTLFIQPVQIAAEVLNEAQNAVAGWRRVLDVLDVAPDVADPGEQGVSLPEGPIDVRFED
                     VSFTYGGPIVLDDVDLDIPAKTRVAVVGETGSGKTTFAKLLTRLMDPTTGTVRLSGVPL
                     DQLRFDSLRSRVVMVPQDGFLFDATVAENVRFARPDLTDADLALAFTELGLTDWVESLP
                     NGLATRVGERGEALSVGERQLVALARAYVADPDLLVLDEATSAVDPATEVRLQRTLDAV
                     TRGRTTVAIAHRLSTAQAADEVIVVDKGRVVQRGPHDKLVQDSGSVYGKLYASWLEQTR
                     "
     gene            complement(15490..16236)
                     /locus_tag="CHC05_RS21395"
                     /old_locus_tag="SAMN05421812_108265"
     CDS             complement(15490..16236)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (36-130). E-value: 4e-07. Score:
                     20.3. Matches aSDomain: nrpspksdomains_CHC05_RS21395_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013382.4"
                     /locus_tag="CHC05_RS21395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108265"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_089251556.1"
                     /transl_table=11
                     /translation="MAESLPFDRVADSYDETRGGEQRGRQFAAALAPHLLPGRVLEIGV
                     GTGLVAAALAQVHGVPAVGVDLSPAMLTHAHTRLGARVAVGDARGLPVRDAAVDNAFFA
                     GALHVIVDVDAAFAEAARVVRPGGRVLALSASSDRDRHDVFAPLLEGLPGRDRVDLPDA
                     VLAAATEAGLRTRESREVTVGAAATSPNQIAETIETRAWSYLWNVDGAVWVSTVMPIVQ
                     GLRDLPDPDEPRDRRLTFQLSVFEKP"
     aSDomain        complement(15847..16128)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CHC05_RS21395_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="4.00E-07"
                     /label="CHC05_RS21395_oMT.1"
                     /locus_tag="CHC05_RS21395"
                     /protein_end="130"
                     /protein_start="36"
                     /score="20.3"
                     /tool="antismash"
                     /translation="PGRVLEIGVGTGLVAAALAQVHGVPAVGVDLSPAMLTHAHTRLGA
                     RVAVGDARGLPVRDAAVDNAFFAGALHVIVDVDAAFAEAARVVRPGGRV"
     gene            complement(16247..16879)
                     /locus_tag="CHC05_RS21400"
                     /old_locus_tag="SAMN05421812_108266"
     CDS             complement(16247..16879)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014692418.1"
                     /locus_tag="CHC05_RS21400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108266"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_089251558.1"
                     /transl_table=11
                     /translation="MVRRTGRRPGNPDTRDAILATARTAFAEKGYDGASIRHIATGAGV
                     DPALVHHYFGTKDKLFLAAMNAPLDPGELIPEVLAGDQDAIGERLVRFFLSIWDSPAGK
                     AGVAMLRSAVSSEWTAKLFREFVVSQVLRRVRQLVPMPPAEAPMRVSLVASQLAGLAMA
                     RYVIKIEPLASASPDVLVAAIGPTIQRYVFGDLSGIWPSPPPPDAAG"
     gene            complement(16940..17674)
                     /locus_tag="CHC05_RS21405"
                     /old_locus_tag="SAMN05421812_108267"
     CDS             complement(16940..17674)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018830540.1"
                     /locus_tag="CHC05_RS21405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108267"
                     /product="ABC transporter permease"
                     /protein_id="WP_089251560.1"
                     /transl_table=11
                     /translation="MSPHILASTIGRIVRQLRHDRRTVGLVIVVPLLLLTLLYFMFDGG
                     LMFDRVALVMLGIFPFIIMFLITSIAMLRERTSGTLERLFTTPVGKLDLLFGYGIAFGL
                     VAAAQATVAAGLAYWLFDLHTAGSLWLVIVIAVANAVLGVALGLLCSAFARTEFQAVQF
                     MPVVAIPQILLCGLFVARDSMAGWLQVISDVLPLSYSVEALTEVGAHADPTGTMWRDLG
                     IVIGAIILALVLGATTLRRRTA"
     gene            complement(17674..18396)
                     /locus_tag="CHC05_RS21410"
                     /old_locus_tag="SAMN05421812_108268"
     CDS             complement(17674..18396)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014692420.1"
                     /locus_tag="CHC05_RS21410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108268"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_089251562.1"
                     /transl_table=11
                     /translation="METAIEVTDLVINRGKREVLHGFSCAIPRGSITGLLGPSGSGKTT
                     LMRAVVGVQLVASGRVTVLGEPAGSAPLRRKIGYLTQAPSVYDDLTVRENARYFASLYG
                     LGAADAEAALDGVGLSGAAHQLVGNLSGGQRSRASLACAIVGRPEVLVLDEPTVGQDPL
                     LRDELWARFRALAADGATILVSSHVMDEANRCDRLLLIRDGHLIGDDTPAAIKATAGTD
                     DLDEAFLRIIRQQEKAAA"
     misc_feature    18462..18473
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
ORIGIN
        1 agggcgccgc aggcaccgag accggctacg gcgacccgct ggaggcggcg ctggcctggc
       61 agcacgacgg ggccgagtgg gtgcatctgg tcgacctcga cgccgcgttc ggccggggct
      121 ccaacgcggc gttgctcgcg gacgtggtcg gtcgcctcga cgtcaaggtc gagctgtccg
      181 gcggcatccg cgacgacgcc tcgctgcgcg ccgcgctggc caccggggcg gcccgggtca
      241 acatcggcac ggccgccctg gaggacccgg tgtggtgcga ccgggtcgtc ggcgagtacg
      301 gggaccgcgt ggcgatcggg ctcgacgtgc gcggccgtac cctgtcggcg cgtggctgga
      361 cccgcgacgg cggtgacctg ttcgaggtcc tggaacggct cgacaaggcc ggcgccgcgc
      421 ggtacgtcgt caccgacatc accaaggacg gcacgatgcg cgggccgaac ctggacctcc
      481 tgcgcgacgt ctgcgcccgt acccccgcgc ccgtgatcgc ctctggcggc gtttcgaagc
      541 tcgacgacct gcgcgcgctg gccaccctcg aagaggtcgg tgtcgagggt gtgatcgccg
      601 gcaaggcgct ctacgcgggc gcgttcaccg tgcgcgaggc cctggcggtg ctggcgtcgt
      661 gagcgtcgcg gtccgggtga tcccctgcct cgacgtcgac gcggggcggg tggtcaaggg
      721 cgtcaacttc gtcgacctgc gcgacgccgg cgacccggtg gagctcgccg ccgcctacga
      781 cgcggccggc gccgacgagc tgacgttcct cgacgtgacc gcgtcgtccg acgaccgggg
      841 gacgatgctc gacgtggtac ggcgtaccgc cgagtcggtg ttcatccccc tgaccgtcgg
      901 cggcggggtc cgctcggtgt ccgacgtgga catcctgctg cgggccggcg ccgacaaggt
      961 gggggtcaac accgcggcga tcgcccgccc tgagctggtg agcgagatcg cgcagcgctt
     1021 cggcaaccag gttctcgtgc tctcgctcga cgtgcgccgc gagcccggtc gtgggttcga
     1081 ggtgaccacg cacggcgggc gcaagggcac cggcctcgac gccgtcgagt gggccaggcg
     1141 ggtcgctgac ctcggtgcgg gggagatcct gctcaactcg atggacgccg acggcacgaa
     1201 ggccggcttc gacctggagc tgatccgggc cgtccgggcg gccgtcgaca tcccggtgat
     1261 cgccagcgga ggagcgggga cgaccgccca cttcccgccg gccgtcgagg caggcgcgga
     1321 cgcggtgctc gcggccagcg tgttccactt cggagagctg cggatcgccg acgtgaagac
     1381 cgccctgcgc gaggccggca acccggtgcg ctgacccgaa acggggtcgc aagatcaacc
     1441 ccgcgcctgg tgggatgcct gtcatgcgtc tgcgggagaa cctggtgccc ccggccggcc
     1501 tgccccgggc gtacgccctg gtcagcttga tcttcgggat cggggtcggc acgttcatca
     1561 ccggcagcac ggtgttcttc acgcgcgtcg tcgggctcca gccgcacgag atcggcatcg
     1621 gcctgtcggc ggcggccggc gccgtgctgg tctgctcgct gccgctgagc tcgctcgccg
     1681 accggttcgg cccgcgccgg gcctggctgt tcggcgtggc gggcagcgcc gcgggctttc
     1741 tgctgtggcc actcgcgcgc gggttcttca cgttcctcgc gatgatcgtg ttcttcgagc
     1801 tcgtcaacgg cgtcgcgcag gccggccgca acgtctacct gatcgaggcc gtcgacccgg
     1861 agacccgcgt gcgtacgcag gcgttcgccc ggtcctggct caacatcggg tggtcggtcg
     1921 gagccggcct ggccgccctg gcgctggcca tcgacacccg cgcggcgtac ctggccctgc
     1981 cactggccaa cgccgccgtg ctgctggcca acctcgtgct gatcgcgcgg ttgcccgccg
     2041 ggcccgccgg ccgggcccgc acacgcacgc cgggggagcg ccacgtgttc gccgaccggc
     2101 acttcctcgc ggtgaccgtg ctgtgcgcgg tgctgctcgc ctacggcacc gtcgagttgc
     2161 aggtcgcacc gttgtggctg ctcacgcaca ccgacgctcc gaagtggtgg atcggcgtgc
     2221 tgaccctggt caacaccgtg atggcgacga cgctccaggt ggcgatgacc cgcggcgcgc
     2281 acaccctcga cggcgccgcc cgcgccctgc ggctcggtgg gctcgcggcg gcgctgggct
     2341 gcccggtctt ctacctggcc ggagccacct cgggcgtcgt cacgatggtc gtcttcgtcg
     2401 tagcggcggt gcttttcacg ctctccgaga tgtggcagtc cgccggctcg tggacgctcg
     2461 cggcggagct gccgccaccg ggccgccgcg gcgagtactt cggcgccttc cggatgggca
     2521 actcggcgat cgagatggtg gcaccggcgt cgctgatcgc gctggccgtg accaccggag
     2581 gctggggctg gctgctcatc ggcggcgtct tcctggctgc gggcctgtcc gccgtgccgc
     2641 tggtccggtg ggccggccgg caccgcgcgg cggcacccgc cgaaccggag ccggcactga
     2701 cctgacgcgc gcgcagaacc ggaccgggcg atcctgcgtc ttggaggcga gaggacgtcg
     2761 tcggcgcacg gggagtggct ttgtcgatca tcagccgtca ggaggcgccg gtcagcacgg
     2821 acccaccgtc ggtcgaggcg gagttcaccg cgttcgtcag cgccaactac ggtcggctgc
     2881 tgcacgtcgc cgacctgctg atcggtgacg ccgggcgggc agaggagctg ctccagaccg
     2941 tcctgacccg cacctatctg cggtggtcga gggtcaggca ggacaacccg ctggggtacg
     3001 tgcgcaccgg gctcgcgaac gcacgcaccg actggctgcg ccgtggcctc ggcagggagc
     3061 ggccgaccgc ggccgtgccg gtcagcgtgt tggccccgga cccctccgag caggtggtcg
     3121 gccgggatgc cgtgcagcgg gcgctcgcgg tgctcacccg gcgggagcgg gcggtggtcg
     3181 tcctgcggtt ctacgaggac ctcagcgagg ccgagatcgc ccgcacgctc gacatcgcgc
     3241 ccggcacggt caagagcacc tgcgcccggg ccctggtcaa gctgcgcgtc tcgcccgaac
     3301 tccaggaggg gaaccggtcg tgaacaccat cgaggacctg cgggccgcgc tcgactaccc
     3361 ggacccgcct gccaagcccg acacccgtgc catcatcgcg cgcgggcggc gccgacgagt
     3421 ggtccgccgg gccgcggtgg gcggcgggct ggccgtggtc gtcgccgggg tcgttgccgt
     3481 caacgcgttg ggcggcacgc cggccccgcc cccggtgctg gtcggatcgg cgccggaccc
     3541 ggccctggtc acggcgtcga cgacggctgt ggcggaggca cccgagcggt tcgacccgct
     3601 gacgcggacg ttgcacgtcg gttggatccc ggccggcctc acgggtcagg gggcggagat
     3661 cagcgtcacc caacagagct tcggcggccg ggacaaggaa tttgccgacg gtgggagaga
     3721 ctacggcctg tcggtgatgc tgctggcgaa gggccgaccg cccaccgact tcatgggtgg
     3781 cctgggaatg ccccgggaat ccgtggaaag cgagaccgac gacgtcaacg gcaagccggc
     3841 cgtgtgcctg agcgacccgg aggtacgcgg ctcgtgcgcc gccctgcagt gggagtacgc
     3901 gccgggtgcc tgggcgcgcg tcgggtacag cggcagcgcc ggtcccaccc cggaggcggc
     3961 ggccgccgtg gcccgccggg tagccgagtc ggtgcggttc accgcgggcg aacccgtccg
     4021 gctgccgttc acgatcggcg gctcgacggc tgagctgccc gccgcgcgca cgcaggtctc
     4081 gatcttcgca cccgcgtacc agcaggaggg tggcgaggtc tggaacgccg acctctgcct
     4141 cgccccgtca ccccgcgacg tggaacgcag cgtcggggac acccggcagc tctgtctcgg
     4201 cgccagcaaa gccgtgggca cgggtgcccg tctcccggac gaccccgagc cgaacgcgac
     4261 ggtggacggt catgacgccc ggatcgtcga catgcagctg atcgtctgga acgtgtccgg
     4321 catccgggtc gacaccacgt actccgactg ggacgtcaac ccgaggtacg cctacgagga
     4381 cctgcgtgtg gccgaggatc ccgccgaccc ggccgactgg ccggtcagtc ggtagtctcc
     4441 gcgcgcccgg cgtactcgag gatcgcggcg gcgtggtcgg cgtcgtccag ggtccagtcg
     4501 ctgtcgtccg ggatcggacg ccggagcaac tgggtgtaga cggtgtcgac cgcgcccacg
     4561 ccggaccggc ggttgcgcca gagcgtgccg ccggccgccg tgacccggaa ccacccgtcg
     4621 accaccgtga tcaggccggc gccggtcagc cgccggaccg cttcctcgac ctcacgccgg
     4681 cctggtagca gttgccgcag gtggtcggcc atcgagagga cgtcggcgag ccgcacgccc
     4741 tcgggtcgtc gagtggtcgc cgagcgcatg tgccgcccgg cgccgttcgc catcaccacc
     4801 gcgacgaaga tccaagcgtc ggatcgccgc cagccgtctt gccccatgga gcaatgatgc
     4861 caacgtcaac gacccatgaa cattggtgtg atctttcgtt tacctgaaac cttcaccagg
     4921 ttcgatgcat catgcagccg gttcggcgat cggttggccg ccgatccggg gcggtgacgg
     4981 gcgcaccgtg aacagtggaa tgaagacgtg gttcaacggt ccgatcagga gcgcgtacgc
     5041 caccgtgccg atgccgacag tgcctccgag cagcacaccg gcgcccagca cggccacctc
     5101 gatcaccgtg cgggtgagcc ggatcgagcg gcccggcttg cggcccaccc acccggtcat
     5161 cagcccgtcc cggggccccg gcccgagccg cgcaccgatg tacaggccgc cggcgacccc
     5221 gttgagcacg atgccgagga ttaagaacgg gatccgcacg gccaacgagt ccggcgtcgg
     5281 cagcagggcg agactcgcgt cgacggcgag gccgatgatg acgatgttgc tgacggtgcc
     5341 gatgcccggc ttctgccgca gcgggatcca gagcagcagc accgccgcgc ccacgatgat
     5401 cacgatggtg ccgaacgaga gcccggtctt ctccgcgagg ccctggtgga acacgtccca
     5461 ggggtccaat cccaaggtgg cctcgatctg gagggccatg ctcgccccgt acagcagaag
     5521 acccaggtag agctgggtca gccggcgggg aagccggtct cgcagggcca tggggtggtt
     5581 gctctcggac gccatgcatg caactctgaa ggccaattgg ttcggtactg aagagccaat
     5641 tcgcgaggag tggatatgac aagcctggtc cggggtagcc aactcgcccg cctgctcggc
     5701 cactggcacg ccctgccggg ccgccggcgg aaccccgact acgccgccct ggccggcgcc
     5761 gtgcggggcc tgctcgccga cggccggctg ccgttgggca tccggctgcc cgccgaacgc
     5821 gagttggccg aggcgctcaa ggtcagccgg accaccgtga cggccgcgta ccgggagctg
     5881 cgcgacagcg gccacctgac cagccgccgc ggcgcgggca gttggaccac cctgcccggc
     5941 ggccaccggg tggccagcac cggcctgtgg accccgctca acgacctcgg catgatcgac
     6001 ctgggttgcg ccgcgctcgc cgcgccaccc gagctgatcc ccgccgcccg cgccgcggcc
     6061 gacgagctgc cgcgctacct gggcgacgcc ggctaccacc cgaccggcct ggtcgagctg
     6121 cgcgaggcgg tcgcccgcgg cttcaccgac cgcggcctgc cgaccagccc cgaccagatc
     6181 atggtcacca gcggcaccca gcaggccctc gacctggtgc tgcggcttac ggtccaggcc
     6241 ggcaacggcg tactcatgga gtcgcccacc taccccaacg cgctcgcggc gctgtcggcc
     6301 cgccgggccc ggatcaccac gcacggcctg gacccggcgg ccggctggga cggcgagctg
     6361 ctgctcggtg cgctgcgcca gagcacaccc cggctggcgt acgtcatccc ggagttccac
     6421 aacccgaccg gccacctgat gccggccgac ctgcgcgagc gcctcgtcgc cgcggcccac
     6481 agcaccggca ccgacctggt cgtcgacgag tcgttcgtgg acctcccgct ggatggtgtg
     6541 gaggtgccac cgccggtggc gatgttcgac cgccactccc gcgtgatcac catcggcggc
     6601 atgagcaagc cgtactgggg cggcctgcgc atcggctggg tccgcgcctc ggcgccgacg
     6661 gtccaacggc tggcggcgct gcgggtcggc gtcgacatgt cgagcccggt gctggaccaa
     6721 ctcgtggcgg cccaactcct ggaccgcgcg gacacgatcg tcccggcccg gcgtttgcag
     6781 ctcgcaaccc aacgcgacgc gctgctggaa gcgttggccg agcatctgcc ggagtggcgg
     6841 gtccagatcc cccacggcgg agtgaccctg tgggcggagc tggacggccc gatctccagc
     6901 gcgctggcgc gggccgcgga ggaggtcggg gtgcggttgg cgccgggtcc gcgcttcggc
     6961 ctggacggga cgttggaacg tttcctgcgg ctgccgtaca cactgccggc tggcgacctg
     7021 atcgacgcgg tcaagcgcat cgctacggtc cgctacgacc tggaccacgc cccgcaccca
     7081 ggctggcgca agccggtcgt catcgcctga ccagattcgc caagaccaga ttcgccaaga
     7141 caagacccag attcggcaag accaggatcg tgtcccgggt ccgcctgggg cgcgaccgtc
     7201 gctcccgccg gggaccgctc cgctgcgctg cgctgccagg tccgcggcgg gtcgcccccc
     7261 agccacacgg ccgagatcta ggtaaatgat tgctgctcca gcagcaatca tttacctaga
     7321 tctgccgata aacgcgtgag cggcggcgtg ttcgcgccga acgggcacca aacgtcagtg
     7381 gctgatcccg ccgggtcgcg ctcctggcgt gtccgtcccg gactcgccgc cgcggacgcg
     7441 tctggtgccg gatctaggta attcgatgct gcgagagcag caatttctta cctagatccg
     7501 gcggcaggcg ggtcgacgcc gcgcgtctgt gcttcgggcg acgtggccgc cggtagatcg
     7561 acgccttggc cgaaggcccg gcgatcgccg acgcgtcgcc aaggcctgcg ccggctcgcg
     7621 ccgcgccgtg ccggctcgcg ccgcgccgtg ccggctcgcg ccgcgccgtg ccggctcgcg
     7681 ccgcgccgcg ccgtgccgtg ccggctcgcg ccgtgccgtg ccgcgccgtg ccgcgccgtg
     7741 ccgcgccgtg ccgcgccgtg ccgtgccgcg ccgcgccgtg ccgtgccgtg ccgtgccgtg
     7801 ccgtgccgtg ccgtgccgtg ccgtgccgcg ccgtgccgtg ccgtgccgtg ccgtgccgtg
     7861 ccgtgccgtg ccgcgccgtg ccgtgccgcg ccgtgccggc tcgcgccgcg ccgtgccggc
     7921 tcgcgccgcg ccgtgccggc ccgcgtccgc ggtcgccggg tgcgggtcgg gtgagtgggc
     7981 agagacagag cggcccgccg gtggctgagt gccaatccgg cgggccttct ggtggcgctt
     8041 agatctcggc gagggtgccc tcgtacatct tgttgatctc gtctgcgaag ttggcctcca
     8101 cgccgcggcg cttgaccttc attgacggcg tgacctcgcc gtcctcgatc gtcaggtcgc
     8161 gggggaggat ggtgaacttc ttgatcgttt cccagcggtt gagtttcgcg ttgagctccg
     8221 tcacgtagcc ctcgaccatc tcgtgggcct ggggtgacgc gacgatctcc gcgtacggct
     8281 tgccggccag gtcgccgctc gctgcccacg ccgcgatcgc gtccgggtcc agggtgatca
     8341 gcatcgtgca gaagttgcgg gcctggccga ccacgatcgc ttgggaggtg tacgggcaga
     8401 tggccttgaa gaggccctcg atgtgcgacg gggcgatgta ttttccgccc gaggtcttca
     8461 ccaggtcctt cttgcggtcg gtgatcttca ggaagcggtc ttcgctgatc tcgccgatgt
     8521 caccggtgcg gaagaagccg tcctcggtga acgcggccgc ggtctcctcg ggcaggttgt
     8581 ggtagccgcg catgaccggt gtgccgcgca gcagcacctc gccgtccgag tcgatcttgc
     8641 actccaggtc gcccagcggc tggccgaccg tgccgatgcg caacccgccc gggcggttga
     8701 cgaagttgcc cgcgctcgtc tcggtcaggc cgtagccctc ggagatcggc aggcccgccg
     8761 ccgcgaagaa ctccgagatg tcgacgctca gcggcgccgc gcccgagacc agcgtgcgga
     8821 tgttgccgcc cagccgggcc tgcagcttgc tgaagaccag cttggtggcg atggcgtact
     8881 gcatgcgaag gcccgccggg accggctggt ccgcctgctc cagctggacc ttgcgcttgc
     8941 ccgtggccac cgcccacccg aagatcttgg ccttggcgcc gccctcggac gtggcgttgg
     9001 tgatcgcctt gttgtagacc ttctcgaaga tccggggcgc gccgcacatc agggtgggct
     9061 tcacgacgcc gaggttgtcg accagcacgt cgatccggcc gtcgacgtag gtcggcaggc
     9121 cgacgtggat gatgccgcac agcagcgtct tgccgaacga gtgcgacagc ggcaaccaga
     9181 gatattgcag gtcgtcggcg cgcaggatgc ccaggtccgc ctgcgcgacg gcctcccagc
     9241 accaacccgc gtgcagcagc tcgacgccct tggggcgccc ggtggtgccg gaggtgtaga
     9301 tcagggtggc caggctgtcg ggggcgatct cggcgaccag ccgctcgatc agctccgggt
     9361 cgccggccag cgcggcggcg ccctgcttct ccaggtcggc catcgtgagc tggggcgggc
     9421 tcgcggccgg gtcggcgtca ccgtcgatca gcacgacgtg ggtgaccgcg ggcaggttcg
     9481 caccggccag cttgccggcc tgcatcgcgt tctccgcgac gacgaccttg gagcccgagt
     9541 cggcgatgat gaaggtcgcg tcctccggct cggtggtcgg gtagaccgtg gtggtcgccg
     9601 cccccgcgca catgatgccg aggtcggcga tgacccactc gaggcgggtg ttggcgatga
     9661 tggcgacgcg ctcctcggcg ccgacgccga ggccgtgcag tccggcagcc agggaccggg
     9721 cgcgctcgcc cacctgctgc caggtcatcc actgcggacc agacgcaccc gggtagccga
     9781 acgcccgcgc gtcgggcgaa gcggcgacac gctggaggaa catgtcgggg atcgaccggt
     9841 aagggacatc gagcgacata tccggaaacc acctttagtc ggccatgtga ttgcggtcac
     9901 tctcacgatt gctaccgaag agtatggcta accggtacgt cgatgccagt ccccgagcgt
     9961 acgtgtcgat catgggctga ccagggtctt tatcctggac tcaggggtgg tagcgcagcg
    10021 cgcccagcga ccagtcgtac gtgccccgca accagcggcg ccgggactgc agcatgcgcg
    10081 acaaccgacc gtcggcgtcg gccagcacct cggcctccaa cgcgccgtag gcggccagcc
    10141 ccgcgttgta ccgcgccgcc gcctcggtca gggccgcccg ctccggccag gtcagctcgt
    10201 acgcgatgac cgtggccagg ttgtgcccgt cgcgcaggcg ttccttcccg tacgagaaga
    10261 cgtcgttgca ccagcacacg agatcggcgg ccagcaggtc gagccggacc acccgcgggt
    10321 cgacccggtc gacggtggcg gccagcccgt ccgtggccag gtcggtcagc gcgaagctgg
    10381 gcagcacggc accggtgtgc cggcgcatct gcacgtactc ggcgaaccgc ggcacccggt
    10441 gcagctgccg gttggtcgcc tcccagagca gggcgaacag gtactcgcgg aaggccgcgg
    10501 cgaacttgag caagccgccc ggccggccca aagcccgcac ccggcggcac aggtcgtgca
    10561 gcgcggccgc ggtcggtccg gccggctggt agcccgcgtg cgcggtcgtg ccgaaccggt
    10621 cgaccacctc gagcagcggc gccagcgcgg gcgcgagccg ggccgggttg gcaccgagct
    10681 cgtcctcgtc gcaccggtcg tcgaacgcga acagccaggt gatcaggtcg gccagcagct
    10741 tgaccgccga cagggacacc tcgggacagg cccgcgccgc gagcgaggcg gcgtcggccc
    10801 gggccagccg ctccctggcg gccggcgacg gcaccaggcc gaacgcgtcc gcccagtcgg
    10861 cggagtgcgc ggcgacctcg gcgaccgctg ggtggaccag cgactcgtac ggcggcgggg
    10921 tcaacgccgt cgccgcgaac gtccgcatcc cacccccagc ccgtacccga tgatgtctgg
    10981 cgaccggccg gcgagggaac gggtggttcg gtcgatgcct cagatcttca gcggggacgt
    11041 ccgcagccga tcggccagct cgggcggacc gtcgatctga acccgggtgg cccgttgccg
    11101 cccggacagg aaataggcga gctcgccggg cgcaccgacc agccggagcg gctcgccgcc
    11161 ggcgcccgtg gtgacctcgc cgaacccggg cgcctgcacc agcagcgcgg ccgggaactt
    11221 gcgcagccgg agccgggcga tcagcgacgc gctcttccag agcgccgcct ggtcctcctt
    11281 gggcaggtcg cgcggctgcc agccggcctg ggcccgccgc acgtcctcgt ggtgcacgaa
    11341 gaactcgagc ccgttcgtca tgccctcgac cagcgggttg ctgaccgggc tccacaacgg
    11401 cgggtttcgg accagttcga cgagatccgg gtacgggcgg gaggcgaacg accgcagcat
    11461 gttgcgcgcg tgcgaccgca gcggcgggat gaacatgccg aggctggcgt ccggccgccg
    11521 ctcgcggatg accaggtgcg cggccaggtc gcgggcgacc caaccggtgc acatcgtcgg
    11581 cgcgtccggg ccgacagtgc tgaaaaggtc ggcaagtttc cgacgttcgg accgtacgaa
    11641 ccgcgacatg gcgagaatcg tagccagggt gtgccacgac acaccccgct gtgacggtgg
    11701 acacatggaa tacccgctcg cccggagggc ttgggtccgg taaggattac ggtggaattt
    11761 cgcggcttac cccctgggtg cagccgagcg gtcagacaga ggggcaaaac atagtggcga
    11821 gcgtgaccag tcgggacgtg ctcgcccggg gcttccgcgt gctcggccgg gccatcaagg
    11881 acgaaccccg catcttcgcg ttcgcggtcg gcggcagcgt gctcttcggt ggcctggtcg
    11941 tgggcagcgc gtacgtgatc gggcacatcg tcgggaagat catcgtgccg gccatcgagg
    12001 acggtgcggt cgacaacgcg ctgctctggc tcggcgcgct cgcggtgctg gcgatcagcg
    12061 tgctccgggt ggtcggcatc ttcggccgcc ggctcggtgc cggctacatg cagttccgcc
    12121 tccaggcccg ctaccggcgc ctggtcaccg gccgctacct cgacctcccg ctctcctggc
    12181 accaccggca cgcgaccggc accctgctct ccaacgccaa ctccgacgtc gaggccgcct
    12241 ggttcccgat cgcgcccctg ccgttcgcgg tcggcacgct ggtgatgctg ctcggcgccg
    12301 tcgggtcgct gttcctgacc gactgggtgc tcgccctggt cggcctggcc accttcgccg
    12361 ggctgttcct gatcaacgtc ttctactcgc gccggatggc gccgcgccag gcccgcgccc
    12421 agctcatgcg gggcgaggtc agcgcgatcg cgcacgagag cttcgacggc gcgctggtgg
    12481 tcaagacgat gggccgcgag ggtcaggaga ccgaccgctt cgccggccag gcccgcgagc
    12541 tccgcgacgc gctgatctcg gtcggccggc tgcggggcct gttcgacccg ctgatggaga
    12601 cgctgccgag cctcggcacg ctggccgtgc tgatcgtcgg cacgttccgg ctgcgggccg
    12661 gcgacatctc ggtgaccgac ctggtcagca tcgcgttcct gttcaccgtg ctggccttcc
    12721 cggtgcgcgc gatcggctgg gtgctggccg agctgccgcg cagcgtggcg ggttgggacc
    12781 gcctccagca cgtgctcacg gccaccggcg agatgcgtta cggcacgata agtccggaaa
    12841 agtcggacag cccggcccga ctcgccttcg acggcgtcga ctacgcctat cccaccggcg
    12901 ccgacaccga cgacatggcc gccgccgcga cgcaggacga gcacggcccg accgtcctgc
    12961 acgacatcag cctcgtcgtc cccgagggcc gcacggtcgc cctggtcggc ccgaccggtt
    13021 ccggcaagtc gacgatcgcc tcgctcgcgg tgcggctggt cgacccggcc accggcacga
    13081 tcagcatcga cggccacgac ctgccggacc tgaccgccgc cgcgctggcc gacaacgccg
    13141 cgctcgtcgc gcagatcccg ttcatcttcg acgactcggt gcgcgccaac gtcgccctcg
    13201 accggcccgg catcgacgac gacgcgatct gggccgcgct gcggctcgcc caggccgacg
    13261 agttcatcgc gcgcctgccc gagggcctcg acacgatggt cggcgagcgc ggcacctcgc
    13321 tctccggcgg ccagcggcag cgcctcacgc tggcccgcgc cctggccggc cggcccaggc
    13381 tgctggtgct cgacgacgcc accagcgcgg tcgacccccg ggtcgaggcg gcgatcctgg
    13441 ccgccctgcg cggcggtgag cagcccacgt cgatcatggt ggtcgcctac cggcgggcca
    13501 cgatcgcgct cgccgacgag gtcgtctaca tcgagcacgg gcgggtggtc gccgccggca
    13561 cccacagcga gctgctggcc agcacaccgg ggtacgccga cctggtcacc gcctacgagc
    13621 gggccgaggc cgagcgggag cgcgagcacg cgtacgagga cgaaggggcg gtgaccgcgt
    13681 gacgaccacc gccaccgcgc cggcgaaagc gaaagtcgtc aacgaaacag cggaggagcg
    13741 gcccgagtcg acctgggcca ccatccgtcg cgggctgtcg ctctcgcccg agctgcgtac
    13801 cggcctggcc ggcaccctgt tcttcgcgat catctcgatg gtgggccggg ccgccgtgcc
    13861 ggtcgccatc cagcaggcga tcgacaaggg catcgccggt cccggcgggc tcgacgtcgg
    13921 cttcgtcggc accgtcgccg cgatcaccgc gggcgtgctc gcggtgacca cgctgtgcgg
    13981 ctacctgatg atgcggcggc tgttcacggt cagcgagacc gcgctggcca acgtgcgggt
    14041 gcgcaccttc cggcacatcc acgacctctc gatgctgcac cagcagtccg agcggcgcgg
    14101 ctcgctcgtc tcgcgggtga ccagcgacat cgaccagatc acccagttcc tccagtgggg
    14161 cggcgtgatc ctgatcatca gcgccggcca gctcctggtc accgccggcg tgatggcctt
    14221 ctactcgtgg cagctcacgc tcgtggtgct ggtcgcgttc gcgcccgccg tgttcgtgat
    14281 ccgggcgttc cagaagcgcc tggccggcgc gtacgggctg gtccgccagc ggatgggcgc
    14341 cctgctcgcg gcggtgtccg agagcgtcgt cggcgcgccg gtgatccggg cgtacggcgt
    14401 ctccgagcgc acccggaccc ggctcaacac cgcgatcgac gggcacaaga cgtcgcagat
    14461 gcgggccctg cgcaccagcg tgatcggctt ctccagcggc gagatcgcgg ccggcctggc
    14521 caccgctgcc gtggtcgtgg tcggcgtcca gctcggcatc ggcggcacgc tgacgatcgg
    14581 ccagctcacc gcgtacctct tcctggtcac gctgttcatc cagcccgtgc agatcgccgc
    14641 cgaggtgctc aacgaggcgc agaacgcggt ggccggctgg cgccgcgtcc tcgacgtgct
    14701 cgacgtcgcg cccgacgtgg ccgaccccgg cgagcagggc gtctcgctgc ccgaggggcc
    14761 gatcgacgtg cgattcgagg acgtgtcctt cacgtacggc ggcccgatcg tgctcgacga
    14821 cgtcgacctg gacatcccgg cgaagacccg ggtggccgtg gtcggcgaga cgggcagcgg
    14881 caagacgacg ttcgccaagc tgctcacccg tctcatggac ccgacgaccg gcacggtacg
    14941 gctctccggc gtgcccctgg accagctccg cttcgactcg ctgcgctccc gcgtggtgat
    15001 ggtgccgcag gacggcttcc tgttcgacgc gacggtggcc gagaacgtgc ggttcgcccg
    15061 cccggacctg actgacgcgg acctcgcgct ggcgttcacc gagctcggcc tgaccgactg
    15121 ggtggagagc ctgccgaacg ggctcgcgac ccgggtgggc gagcgcggcg aggcgctcag
    15181 cgtcggcgag cggcagttgg tcgcgctggc ccgcgcgtac gtggcggatc ccgacctgct
    15241 ggtgctcgac gaggcgacca gcgcggtcga cccggccacc gaggtccgcc tgcagcgcac
    15301 cctcgacgcg gtcacccgcg gccgcacgac ggtcgccatc gcgcaccggc tctcgaccgc
    15361 gcaggccgcc gacgaggtga tcgtggtcga caagggccgc gtcgtgcagc gcggcccgca
    15421 cgacaagctg gtccaggact cgggctcggt ctacggcaag ctctacgcga gctggctcga
    15481 acagacccgc taaggcttct cgaacaccga gagctggaag gtcaggcggc ggtcgcgcgg
    15541 ctcgtccggg tcgggcaggt cgcggaggcc ctgcacgatc ggcatgacgg tggagaccca
    15601 gacggcgccg tcgacgttcc acaggtacga ccaggcgcgg gtctcgatgg tctcggcgat
    15661 ctggttgggc gacgtggccg cggcgccgac cgtgacctcc cggctctcgc gggtacgcag
    15721 cccggcctcg gtggcggcgg ccagcaccgc gtcaggcagg tcgacccggt cgcggccggg
    15781 cagcccttcc agcaacggcg cgaagacatc gtggcggtcc cggtcgctgc tcgccgacag
    15841 ggccagcacc cggccgcccg ggcggaccac ccgcgccgcc tccgcgaacg ccgcgtccac
    15901 gtcgacgatc acgtgcagtg cgccggcgaa gaaggcgttg tccaccgccg cgtcccgcac
    15961 cggcagccca cgggcgtcgc cgaccgcgac ccgggcgccg agccgggtgt gcgcgtgcgt
    16021 gagcatggcg ggggagaggt cgacacccac ggcgggtacg ccgtgcacct gggcgagcgc
    16081 ggcggcgacc agaccggtgc cgacgccgat ctccagcacc cggcccggca gcaggtgcgg
    16141 tgcgagcgcg gcggcgaact gccgaccacg ctgctcgcca ccccgggtct cgtcgtagga
    16201 gtcggcgaca cggtcgaacg gcagggactc ggccatgcgg gccaggctag cccgccgcgt
    16261 cgggcggtgg cgggctgggc cagatgccgg acaggtcgcc gaagacgtag cgctggatgg
    16321 tcgggccgat ggccgctacc agcacatccg gcgacgccga cgccagcggc tctatcttga
    16381 tcacgtagcg ggccatcgcc agcccggcga gctggctggc caccaggctg acccgcatcg
    16441 gcgcttccgc gggcggcatg ggcacgagct ggcgcacccg gcgcagcacc tggctgacga
    16501 cgaactcacg gaacagcttg gccgtccact cgctgctcac cgccgagcgc agcatggcca
    16561 cgccggcctt gcccgcgggc gagtcccaga tcgagaggaa gaaccggacc agccgttcgc
    16621 cgatggcgtc ctggtcgccg gcgaggacct ccgggatgag ctcaccgggg tcgagcggcg
    16681 cgttcatcgc ggccaggaac agcttgtcct tggtgccgaa gtagtggtgg accagggccg
    16741 ggtcgacgcc ggcgccggtc gcgatgtggc ggatcgaggc accgtcgtac cccttctccg
    16801 cgaaggcggt gcgggcggtc gcgaggatcg cgtcgcgggt gtcggggttg ccgggccggc
    16861 ggccggtccg tcgtaccatc actagccttt cttcgggtcg ggcatcgctt gtcgtggcga
    16921 cgcccgaccc cgtttccggt caggccgtcc ggcggcgcag cgtcgtggcg ccgaggacga
    16981 gcgcgaggat gatcgcgccg atcacgatgc caaggtcccg ccacatcgtg ccggtcgggt
    17041 cggcgtgcgc gccgacctcg gtgagtgcct ccaccgaata ggacagtggc agcacgtcgc
    17101 tgatcacctg caaccagccg gccatcgagt cgcgggcgac gaacagcccg cagagcagga
    17161 tctgcgggat cgccaccacc ggcatgaact gcacggcctg gaactcggtg cgggcgaacg
    17221 cgctgcacag caggccgagc gcgacgccga gcaccgcgtt ggccaccgcg atcacgatga
    17281 ccagccagag gctgccggcg gtgtgcaggt cgaacagcca gtaggccagg cccgccgcga
    17341 cggtcgcctg cgcggcggcc acgagcccga acgcgatgcc gtagccgaag agcaggtcga
    17401 gcttgccgac cggggtggtg aagaggcgct ccagcgtgcc gctcgtgcgt tcgcgcagca
    17461 tcgcgatgct ggtgatcagg aacatgatga tgaaggggaa gatgccgagc atgaccagcg
    17521 cgacccggtc gaacatcagc ccgccgtcga acatgaaata gagcagggtc aacagcagca
    17581 ggggtacgac gatgacgagc ccgaccgtgc ggcggtcgtg ccggagctgc cggacgatcc
    17641 ggccgatcgt gctggcgagg atgtggggag acatcacgcg gccgccttct cctgttgacg
    17701 gatgatgcgc aggaacgcct cgtcgaggtc gtcggtgccg gcggtggctt tgatcgccgc
    17761 cggggtgtcg tcgccgatca ggtggccgtc gcggatcagc agcagccggt cgcagcggtt
    17821 ggcctcgtcc atgacgtggc tggagaccag gatcgtggcg ccgtcggcgg ccagggcgcg
    17881 gaaccgggcc cagagctcgt cgcggagcaa cgggtcctgg ccgacggtcg gctcgtcgag
    17941 gacgaggacc tccgggcggc cgacgatcgc gcaggccagc gaggcccggc tgcgctgccc
    18001 gccggacagg ttgccgacga gctggtgcgc ggcgccggag agcccgaccc cgtcgagggc
    18061 ggcctcggca tcggccgcgc cgagcccgta gagcgaggcg aagtagcggg cgttctcgcg
    18121 gaccgtgagg tcgtcgtaga cgctgggggc ctgcgtcagg tagccgatct tgcgccggag
    18181 cggcgcggag ccggccggct cgccgaggac ggtgacccgc cccgaggcga cgagctgcac
    18241 gccgacgacg gcgcgcatca aggtggtctt gccgctgccg ctgggcccga gcagcccggt
    18301 gatgctgccg cgcgggatgg cgcagctgaa cccgtgcagc acctcgcgct ttccgcggtt
    18361 gatcacgagg tcggtgacct cgatcgcggt ctccatcgtt cctccgtctc tgaaattcaa
    18421 cgcctgttga actcaacggt agatgaaata gatgggtgta cgcaagcgaa cgccccggcc
    18481 ccctacacgt tcggggggac cggggcgtcg gtttgtcttg ctagagcgcg agcacccggt
    18541 cgaggaagtc gcggtagcgg cgcatcgcca cccgcatcgc ctcggtgtcc ggcgcgtcgt
    18601 tgtcgcgccg cgggtcgagc tcgacctgct cggcgagcag cgtctcggcg agctgctgca
    18661 ccgcccgggc caccagggcc tgagcgtgcc cgagggcctc ggtcggctcg tcgacgaact
    18721 gggccttgac ttcgtgccac tcggaccgca gcgcgtcggc cgcgtcggcg ctccacacgg
    18781 cgatccgcgt ctccggcacg tcacccggac gcagcggcgg cccactgacc ggccgcacgt
    18841 ccgcggccgg cgacccgaga tcggccaacg tcggcgcggc gaccacggga accacctctg
    18901 ccgcgtcgtc gtccggctcg tcgccctcgg ccacgtcgtc gacgggctga ggcgcctcgg
    18961 cggtctccgc cagcccctcc tcgtcggccg ccgtctcctc cgccggcgcc tcgacagcgg
    19021 cggtctcgac cagctcctcg tccgcctcgg ccgcgacctc gtcggcctcg ggctcgccgt
    19081 cagcctccgc ggcttcgggc tcggccgcga cctcggtcac cgcctcgggc tccgcgtccg
    19141 cagcgtcttc gtcgtcagtc tcgacgtcag cgacagcttc cggctccgag tcatcgtcgg
    19201 cagcggcctc gggctcggtc tcggcgacgg cttccggctc ttcgtccgcg tcggcgtcgg
    19261 cctcgacatc agtcgcggct tcgggctcaa cgtcggcaac ggcttcgtcg gacgctgcca
    19321 cgtcctcgtc ctcggcctcg gcgaccgctt cgggctcggc gtcgtcggcc tcggcaaccg
    19381 cctcggtttc cgcgtccgcg gcttcttcgt cgtcgctctc gatctcggcg acagcttccg
    19441 gctctttgtc gtcgtgcgcc tcgtcgtcgg cctcggcctc ggcgtcggac tccgccgcaa
    19501 cctcggcgac ggcttccggc tcgtcgtccg cgtcggcgtc gacctcggcg tcgctgtcgc
    19561 tgtcggcctc gacatcggtc acggcttcgg gctcgacgtc ggcgacgtcc tcgtcggtgg
    19621 cgtcgtcagt cgcagcctcg tcgtcggcct cggccaccgc ctccggctcc gcgtccgcag
    19681 cgtcgtcctc ggtctcggcg acggcctcgg ccgctgcttc gccgtcgtcc tcggtgacgg
    19741 cctcgggctc ggcgtccgtg gcgtcctcgt cgtcggtctc ggtgacggcc tcgggctccg
    19801 cgtccgcgct gtcctcctcg tcggcctcgg acgccgcttc ggcgtcctcc tccgcaacgg
    19861 cttccggctc ggcgtcctcg tcggtggtgg cctccggtgc cgcttcgtcg ccggcatccg
    19921 tgacggcttc ggcttccgcg tccgcgatgt cctcgtcgtc ggtctccgtg accgcctcgg
    19981 gctcggcctc gacggcctca gcctcggctg cttcagcgtc agtctcgacc gcgtcagcgt
    20041 cagcgtccgc ttcggcttcg actgcgtccg cgtcgagcgc gtccgcgtcc gactgggcct
    20101 ccgcgtcgat cacgtctgcc tcgaccgcgt cgggctctgc ctcgaccgcg tcgggctctg
    20161 cctcgaccgc gtcgggctct gcctcgaccg cgtcgggctc cgccccaacc gcgtcggcct
    20221 ccgcctcggg cgcgtcggcc tccgcctcga cggcgtccgc ttgggcctcc gcctcgacag
    20281 cgtcggcctc ggcctcgacc gtgtcggcct ccgcgtaagc ctctgcctcg accgtgtcgg
    20341 tctcggcgtc agcctcagct tcgaccgtat cggtctcggc ctcgggggcc gggtcggtcg
    20401 cggtgtcggt ggtctcggcc gcgtcggtgt ccacagtggt gaccgccgcc ggttccgcgc
    20461 cctcggcggg cgtgtcggtg gtcgacgcgg cctcctcggc cagcagcgcc tgccactcgc
    20521 gctcgaactc cgggtcggcc tcggccgcgg cggccgcggc ctcctcggcg gcggccggct
    20581 cggtctcgcc gacctccgcc gcggccgcct cggcctcggc caccgccgac gcgtccgccg
    20641 cgtccagggc ggcctcggcg tccggcgcgg cgctgtccgt ttcggactcc gtggatgcgg
    20701 gagcggtcgc ccacggggaa gcgaactggc tcgtcatcgg aggaagcgcc ggcgtggccg
    20761 gttcactcgg acggatgaca ggggtctcga tcgtggtctc ggtcagggcc gccgacaccg
    20821 ggccggcaga caccgggccg gccggctcgg tggtctcggc cgcctgggcg gcggcgaggg
    20881 cgtcgagcgc cgacaccggg ccgtcgtcgc cgggcgggcg ctggccgggc agggagatgg
    20941 tgggctcg
//
