LOCUS       NZ_FZPH01000008        24400 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Asanoa hainanensis strain CGMCC 4.5593, whole genome shotgun
            sequence.
ACCESSION   NZ_FZPH01000008
VERSION     NZ_FZPH01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Asanoa hainanensis
  ORGANISM  Asanoa hainanensis
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Asanoa.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900188485.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 02:44:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,204
            CDSs (total)                      :: 8,124
            Genes (coding)                    :: 7,995
            CDSs (with protein)               :: 7,995
            Genes (RNA)                       :: 80
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 20 of 129
            Pseudo Genes (incomplete)         :: 110 of 129
            Pseudo Genes (internal stop)      :: 8 of 129
            Pseudo Genes (multiple problems)  :: 8 of 129
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:45:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 170597
            Orig. end                         :: 194997
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FZPH01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24400
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24400
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24400
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14400]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14400
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(733..748)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.43"
                     /tool="antismash"
     gene            1177..2205
                     /locus_tag="CHC05_RS20890"
                     /old_locus_tag="SAMN05421812_108166"
     CDS             1177..2205
                     /NRPS_PKS="Domain: Beta_elim_lyase (5-273). E-value:
                     7.1e-81. Score: 263.5. Matches aSDomain:
                     nrpspksdomains_CHC05_RS20890_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018730697.1"
                     /locus_tag="CHC05_RS20890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108166"
                     /product="GntG family PLP-dependent aldolase"
                     /protein_id="WP_089251384.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.7e-08, bitscore:
                     26.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELVDLRSDTVTQPSEGMRAAMASAVVGDDVYGEDPTVNALEAS
                     VAALFGHEAALFAPTGSMANQIAIQLSVPPGEELLCDGDAHVVTYEIGAAAAIGGVSTR
                     TWTPVGGDIDPDVVIDMIRPAGYHAVPTRAIAVEQTHNRGGGGVIPLSTLEALRAASTA
                     AGVALHCDGARIWHAHVADGVPLRTYGGLFDTLSVCLSKGLGAPVGSLVVSTAANIERA
                     RVIRKRMGGGMRQAGVLAAAGAYALEHNIARLADDHAKAARLAEALAPFGVVAGAVRTN
                     LVPLDLRKSPLDAHALAAAARERGVLVSVLGPQVARLVTHMDVDDAAIDHAVDVLPKIF
                     RD"
     aSDomain        1192..1995
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CHC05_RS20890_Beta_elim_lyase.1"
                     /evalue="7.10E-81"
                     /label="CHC05_RS20890_Beta_elim_lyase.1"
                     /locus_tag="CHC05_RS20890"
                     /protein_end="273"
                     /protein_start="5"
                     /score="263.5"
                     /tool="antismash"
                     /translation="DLRSDTVTQPSEGMRAAMASAVVGDDVYGEDPTVNALEASVAALF
                     GHEAALFAPTGSMANQIAIQLSVPPGEELLCDGDAHVVTYEIGAAAAIGGVSTRTWTPV
                     GGDIDPDVVIDMIRPAGYHAVPTRAIAVEQTHNRGGGGVIPLSTLEALRAASTAAGVAL
                     HCDGARIWHAHVADGVPLRTYGGLFDTLSVCLSKGLGAPVGSLVVSTAANIERARVIRK
                     RMGGGMRQAGVLAAAGAYALEHNIARLADDHAKAARLAEALAPFGV"
     gene            2275..3069
                     /locus_tag="CHC05_RS20895"
                     /old_locus_tag="SAMN05421812_108167"
     CDS             2275..3069
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHC05_RS20895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05421812_108167"
                     /product="hypothetical protein"
                     /protein_id="WP_089251386.1"
                     /transl_table=11
                     /translation="MANAGLWRWSAWAFLAVAGALVLATLAGAAPVLSAVAAAAAFLVA
                     GVTLVVRRPPRVAAWGSLTVASGSVVFRIYAAVTGPVMVGGRSGGLAGGDIRALVLYPA
                     LAVGLVLLGGTGAAADLTDSLDASVVTLGVFVLLWLFLLHGQIVPTGARLVVSGLRPVG
                     ISVVLGALVRLLFVVRPRAPTIRFVAVGVVLALVGAIGLVARQAGYDVDGRLFGGGIFA
                     VGFAVLIAVALLRPSSAEVPARRGEGLPAARLSRGRPRCSSR"
     gene            3093..3305
                     /locus_tag="CHC05_RS41575"
     CDS             3093..3305
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHC05_RS41575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_179266295.1"
                     /transl_table=11
                     /translation="MTAVAFGQFNPGSPEDFGPPVLAAALIALLLLWRLSLLARVADAP
                     RSSGWWSVSCAGSRRSSPTARRTTR"
     gene            3239..3802
                     /locus_tag="CHC05_RS20900"
                     /old_locus_tag="SAMN05421812_108168"
     CDS             3239..3802
                     /EC_number="2.7.7.65"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /locus_tag="CHC05_RS20900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108168"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_179266296.1"
                     /transl_table=11
                     /translation="MVVGELRGLQAELAYRASHDPLTGLSNRSVLMERLTALPPRRSHA
                     LLLVDLDGFKEINDSLGHPTGDELLVSLGRRLTSLAPPGSTLVRLGGDEFALLLPSTAE
                     AGGLAVGGTICARLRVPYPSTHGELAVSASVGVTAGPLAARSPADLLREADLALYAAKA
                     AGKDRAAAYRPDLAPPGLGVQGRQ"
     gene            complement(3779..4753)
                     /locus_tag="CHC05_RS20905"
                     /old_locus_tag="SAMN05421812_108169"
     CDS             complement(3779..4753)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015623562.1"
                     /locus_tag="CHC05_RS20905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108169"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_089251390.1"
                     /transl_table=11
                     /translation="MTLLRLSPTALARCRFALSPLAETLGSLIALHRPAPEPWLKSWHT
                     ANQPGFQKWLAGDPFAAGLLALVSATKWLPDMVAVPPTGGTRTRLRDELKEVATFTDDE
                     IRATVATAVTKSWEPQDTRWLSGADLGPRTAEVLAEGWRRHVAKDWPRRRALLERDIMH
                     RAGLLAAYGWKEAVKNMTRHSVWVGDDAIRFSEQDYPDRWITDEGLVFVPKTAGVGSWT
                     CERPPLYALVYPARGPAAEVAGPAGDPLGSLLGPGRARVVRELRRAATSTQLAYTLDVS
                     LGTVSTHLAVLRDAGVVAGARVGRAVVYRLTERGTDLLSTLDT"
     gene            4813..5994
                     /locus_tag="CHC05_RS20910"
                     /old_locus_tag="SAMN05421812_108170"
     CDS             4813..5994
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015623563.1"
                     /locus_tag="CHC05_RS20910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108170"
                     /product="MFS transporter"
                     /protein_id="WP_245871096.1"
                     /transl_table=11
                     /translation="MLFTPGFRAFYLGRLVSLAGSAMTPIALAFAVLDASGRPSDLGIV
                     LACQIVPHLALLLVGGVVADRLPRLAVLVAANLGAGLTQGGIALVLISGAYRLWLVTGL
                     ALLAGAWEAFTSPALRGIVPEIVSTDHLQRANSLLSATRSAVLIVGPTVSGLVVVAAGG
                     GWAIAVDAVSFVAAAAFLSRLPRVAPAPAAGARLLHDIRDGWRVFVAIPWVWPVAVAYA
                     VINLVNVGPWQILGPALTQQRSGEAAWGMVLSVRAVGLLAMSAVMYKLTLRRPLRFGRL
                     AGALGACSLLALGLGLHPVALAACAFLGGVGFAASGITWESAVQQHVPSAHLGRVSSID
                     DLLSFAAIPAGQLLVGPAAAAWGGARVALACGVVFAVAALAPLGVRAVRGLGQ"
     gene            complement(5983..6825)
                     /locus_tag="CHC05_RS20915"
                     /old_locus_tag="SAMN05421812_108171"
     CDS             complement(5983..6825)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018726795.1"
                     /locus_tag="CHC05_RS20915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108171"
                     /product="deoxyribonuclease IV"
                     /protein_id="WP_245871098.1"
                     /transl_table=11
                     /translation="MQLIGSHTPSGGGIAKTALPYLDAAGSRAAQVYVSNSRGWALPPG
                     NPDQDALFRAGCEERDVPVYVHASLLVNLGSPTPETVERSTATLAHALTRGTAIGARAV
                     VFHAGSSVDPEHYDAALKQVREALLPLLDQDGPLLLVEPSAGGGRSLASRVEHLTEYFD
                     AVDHHPRLGVCFDTCHAWAAGHDLAGPGGMTATLDLLTATVGAGRLKLVHANDSKDTCG
                     SLRDRHETIGKGTIGTAAFAELLRHPSTQGLPIIVETPSGKAHEGHAADIATLRGLLA"
     misc_feature    complement(5992..5994)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6816..8801)
                     /gene="pknB"
                     /locus_tag="CHC05_RS20920"
                     /old_locus_tag="SAMN05421812_108172"
     CDS             complement(6816..8801)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018907613.1"
                     /locus_tag="CHC05_RS20920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108172"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_089251394.1"
                     /sec_met_domain="Pkinase (E-value: 1.6e-50, bitscore:
                     166.1, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 4.6e-09, bitscore: 30.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIQVADSLLGTLVDGRYRIRGRVARGGMATVYTATDERLERTVA
                     LKIIHPAQARDPEFLERFTDEAKTIARLTHPNVVAVYDQGRHAGLPYLVMEYVRGHTLR
                     DVLAQRRRLNPGEALAILEQMLAAISAAHRAGLVHRDVKPENVLVAEAPSGGPGNLVDS
                     VVKVADFGLARAVEASATDGDGGQLMATVAYVAPELVTDGRADPRSDVYSAGIVLFEML
                     TGRVPYDGAQPVEVAWQHVDRDVPAPSTLVPGIPPVVDELVSRATRRDPQARPTDAGAF
                     LSAVQVARDDLGAANANTALLRQVSDRTVTIPRVTGPTAEPARPTWARLPGQAEPPPSG
                     RRRAPEPAYDDYDDDPGGKGKLAERYRMVMANPRGRMAVAASIVLVGLIFAISGWWWGM
                     GRYTVAPQLAAMTKAAAEQQATRGGFTIAYGEPQFDETVEKDVVLSQQPAAAGRILKGG
                     TITLVLSLGAERYTVPDVAGMTLQLATTELQERKLQIVKGADRYDDNLPKGTVVATDPP
                     VDTETKPGDKVTVFVSKGKAPLSVPRVVGKNVNEARNELIALGLEPLISYKKSDQPRDT
                     VTKQTPSDGAGVEPGAKIELEVSEGPPQVVVPRLIGLPCQQAVQQVQGMGLTPNPQLNP
                     NGTVFAQQPNENTPVEPQSQVVLFCN"
     gene            complement(8875..9561)
                     /locus_tag="CHC05_RS20925"
                     /old_locus_tag="SAMN05421812_108173"
     CDS             complement(8875..9561)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHC05_RS20925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05421812_108173"
                     /product="hypothetical protein"
                     /protein_id="WP_089251396.1"
                     /transl_table=11
                     /translation="MTTWRGVRKELEGAWRSIQYDLSRAKTRRTDGEETTELIFPEQNR
                     PPRRLRATGGFVLVSLVGAIGTYFAVVNGLGALLEPGQKAEGEKPASVVAGAAGTGQRT
                     DADARPDQSVRIARQGGPLTVAGRQASAGGAGSSDTHDGVPGGAGPAPKPELPRGAPVP
                     EDSDDAPPQTETPTPTPSPTPTPAATDEPSATPSPTPSASEPGDEPTDEGRKRHRHHRH
                     DQDENP"
     misc_feature    9536..9552
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.09"
                     /tool="antismash"
     gene            9656..9997
                     /locus_tag="CHC05_RS20930"
                     /old_locus_tag="SAMN05421812_108174"
     CDS             9656..9997
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463089.1"
                     /locus_tag="CHC05_RS20930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108174"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_245871100.1"
                     /transl_table=11
                     /translation="MTETVPAQWLPLPDVAERLDVSISKVHQMVRDGSLLAVRRDGVLR
                     VPAELVANRTVLKHLPGVITLLHDAGYNDEECLRWLYATDETLPGYPAAALGGDKATEV
                     KRRAQALGF"
     gene            10001..10330
                     /locus_tag="CHC05_RS20935"
                     /old_locus_tag="SAMN05421812_108175"
     CDS             10001..10330
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688676.1"
                     /locus_tag="CHC05_RS20935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108175"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_089251398.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 1.6e-20,
                     bitscore: 67.7, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFVYLAVLVGCLAGALWLEPALRVNVLRRWRRLLLTLVPVMAVF
                     AAWDILAIAAGHWSFDPRQTTGVVLPGGLPLDELLFFLVVPLCSILGFEAVRAVLRLPA
                     GDERP"
     gene            10327..10686
                     /locus_tag="CHC05_RS20940"
                     /old_locus_tag="SAMN05421812_108176"
     CDS             10327..10686
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688677.1"
                     /locus_tag="CHC05_RS20940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108176"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_089251400.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 1.7e-17,
                     bitscore: 57.9, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYTTAALVGALLALVLDLAVLRTGLVRRRVFWATYPIIVFFQLL
                     SNGVLTGRDIVRYDPSAIVGVRLVYAPVEDLVFGFALVLSTLSLWVWWGRQGVQREPAA
                     GTGSSWLLRRLRKRK"
     gene            complement(10620..13067)
                     /gene="mptB"
                     /locus_tag="CHC05_RS20945"
                     /old_locus_tag="SAMN05421812_108177"
     CDS             complement(10620..13067)
                     /codon_start=1
                     /gene="mptB"
                     /inference="COORDINATES: protein motif:HMM:NF038066.1"
                     /locus_tag="CHC05_RS20945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108177"
                     /product="polyprenol phosphomannose-dependent alpha 1,6
                     mannosyltransferase MptB"
                     /protein_id="WP_144022701.1"
                     /transl_table=11
                     /translation="MRGLDSPWGLRVTGLVGVAVVAAGAYEAGALPGRDPGLGLRGPGT
                     PGAGFWWGLAAWVVGLAIVSGAWWRIGSRLGGLGSRWLITTGALWALPLLLAPPLASRD
                     VYSYACQGEIWRSGLDPYAIGAADGGCLWSNAVPDLWQHTPAPYGPVGIALSGAAAAVA
                     RAVGGPADHRLLVAVTVLRLVALVGGVLIAVYAGRLANAVGVRPESARWLGLLSPLVAV
                     HLVSGAHNDALTAGLLVAALAVAVPAVASRGPATVVLATPARDVPAAVSGPATTRSNDP
                     GRETGEQSPHAARVSTGDAVTPGSVSRHGALAAETRSRFGPAIEAGSPTDIETETGYPA
                     GTSNATWSGEPTGTSNATWTSNPTETSHATWNGEPTGTSNATWTSNPTETSDATWNGKP
                     VRAPSQAYRGMSWGSAVGAGAFLGLAVGVKVTAILALPFVVLLVAGWRLRRGTPPWVTI
                     ALAGLTVTGTGALVFAAAGLATGLDLGWVGALSDTGSLVQWTSLPTGIGMAIGYVFRAA
                     GHPGAVDATVDVARACGIAALAVIGLGLCWRALRATLALHPAYALPAPRRASTEADASP
                     APRQPGRPSAATSDVQPATSRVTSHTEHQPNTASADAQPATNRVASHTEHQPNATSAEA
                     QPATNRLTSHTEHEPSGAAAQAQQETSRVTPDSEPHTSRVAAHSGPPTGRDPRDAELEP
                     NDAATRGRAGTATRREVVAACGWALVAAAVLLPVFYPWYALVPLAVLACATPPGKTRTA
                     LATAAIVVTALALPNGLGLPVLTKLPGAIVDVAILVGGALAYFRFRNRRSNQDDPVPAA
                     GSR"
     gene            complement(13417..14400)
                     /locus_tag="CHC05_RS20950"
                     /old_locus_tag="SAMN05421812_108178"
     CDS             complement(13417..14400)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735118.1"
                     /locus_tag="CHC05_RS20950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108178"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_245871131.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.6e-46, bitscore:
                     151.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEVDSALAPVADAIEGFVLRGGKRLRPAFGYWGFRGAGGNDSDQ
                     VVKALAALELVQASALIHDDLIDRSDTRRGEPAVHRRFATRHRAHGWTGDADGFGDSAA
                     VLLGDLCLVWSDELLHAGGLDPAALSRARPVFDAMRTEVTIGQYLDVLTQATGDTSVER
                     AGKVARLKSAKYTVERPLLLGAALAAAPAEVEAAYSGYGLPLGEAFQLRDDLLGVFGDP
                     AQTGKPAGDDLREGKRTFLVAATLEAADESGRRDLQRLLGSPDLDAAGIAHLREVIVAS
                     GAAERTERRIGVLLDAALAAIESAPIDGEARAALIDLAHAATTRTD"
     misc_feature    14430..14445
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.94"
                     /tool="antismash"
     gene            complement(14802..16187)
                     /locus_tag="CHC05_RS20955"
                     /old_locus_tag="SAMN05421812_108179"
     CDS             complement(14802..16187)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287635.1"
                     /locus_tag="CHC05_RS20955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108179"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_245871101.1"
                     /transl_table=11
                     /translation="MMSASPPHPFDAAGPRPPFGPYLAQLRLRRGWSQLRLAEQLCAAS
                     GSPTVTRHEVSRWEREDRLPADFWLGWLAAVLDTPVDGLAAAAERSRLRHRLAAPGQAG
                     PGRPESRDRVGLDLLGLAHTWLAGDPPPLIGPPRAAPPATAWCERPTVAEVTARLVAAR
                     RLDDVLGGADLASAVQRLGAATAQATTPPAGATLTRRAARLRAEVAQLRGWTLADAGDP
                     LGALSAYRAALGAAAAAGDRPLAGHVLGSASHLLAGSGDPAPALLLARTAYAGSRRALS
                     ASGRALLLHRIAFAAAAAGLRGAAEAALVAAQRATERRAAEHDPPWLYWLDEGELDALA
                     GRCLVVLGRPNRALPLLTRAAARSGQPRTGALDKAWLARARLDTGEAEGALLVAGAAVL
                     DTIRSGSTRALDLLTAFGDRIAPHARLPAARDYADLLVAARPYLPRPLRDEPVGGHRVA
                     GDD"
     misc_feature    complement(15285..15287)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16104..16106)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16289..16302
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.44"
                     /tool="antismash"
     gene            16426..17343
                     /gene="metF"
                     /locus_tag="CHC05_RS20960"
                     /old_locus_tag="SAMN05421812_108180"
     CDS             16426..17343
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785290.1"
                     /locus_tag="CHC05_RS20960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108180"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_089251404.1"
                     /transl_table=11
                     /translation="MALGLPSILPGSQPSIGDLIREAGPTFSFEFFPPKTPEGEVQLWR
                     AIRELEPLHPSFVSITYGAGGTTRDTTVSVTERVATETTLLPMAHLTAVNHSVAELRNV
                     IGRLAAAGIRNILAVRGDPPGNPNGEWVRHPEGVDYAEDLVKIIRESGDFCVGVAAFPY
                     KHPRSADIASDTDFFIQKCRAGADFAITQMFFDGDDYLRLRDRVAAAGCDTPILPGVMP
                     VTRMSTIARSEQLSGAPFPPALAEQFARVADDADAVRKLGIEQASEMCARLLAEGVPGI
                     HFITLNRSTATREVWQHLRVDAGV"
     misc_feature    16458..16472
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     gene            17374..18051
                     /locus_tag="CHC05_RS20965"
                     /old_locus_tag="SAMN05421812_108181"
     CDS             17374..18051
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287633.1"
                     /locus_tag="CHC05_RS20965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108181"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_089251406.1"
                     /transl_table=11
                     /translation="MGTRLGWHDYASRWAALHGGFDPRQAGTVVRGWVRLSYEIGSRLG
                     RLRISPTAVTTVGLGLCAATPIAATRAPEGLVTAAILVILAAVADSVDGAVAVATDRTT
                     RLGYVYDSVADRLGEICWLTAFWVAGAPAPLVFTAGALSWLHEYIRARATAAGMTEIGT
                     VTVGERPSRVSVTTVAFLAAAGAGAVNRDLTPGTLTVFLAIWILLATFGLAQLLRAVRR
                     LLR"
     gene            complement(18143..18730)
                     /locus_tag="CHC05_RS20970"
                     /old_locus_tag="SAMN05421812_108182"
     CDS             complement(18143..18730)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016144.4"
                     /locus_tag="CHC05_RS20970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108182"
                     /product="GrpB family protein"
                     /protein_id="WP_144022702.1"
                     /transl_table=11
                     /translation="MRMPPLPAPAPPVTEEWLRARNVGDPPRLTAPIMISAYDPVWPLL
                     YARHATRIRAALGLVALAVDHVGSTAVPGMAAKFRIDIDVVVTDPRDEDAYLPALSSAG
                     YVLRLREPDWYERRALHGFDPPCNVHVFPPDCDEHLRHLILRDWLRTHPEDRSRYAAEK
                     RRIAQSGVTYMAEYANQKSTVIIDILKRAGLT"
     gene            complement(18741..20189)
                     /gene="crtI"
                     /locus_tag="CHC05_RS20975"
                     /old_locus_tag="SAMN05421812_108183"
     CDS             complement(18741..20189)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015620037.1"
                     /locus_tag="CHC05_RS20975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108183"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_089251410.1"
                     /sec_met_domain="DAO (E-value: 5.1e-11, bitscore: 36.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEVVVVGAGVGGLACAARLAATGHHVTVYERSTVVGGKLGRRVV
                     ARPEGVFRFDTGPSLLTLPQVFDELFADLGGVAPPLVPLNPVVRHVFADGTVLDSCADP
                     AEFAERIGAALGAEAALDWQGLWRRAGRVWDASWRDILRRPVDSPAALAGLAWRLGDLA
                     AVAPGQSLRGLGLRRLRDPRLRMLLDRYATYTGADPRRAPAALAAVPYAELSFGGWYVP
                     GGLGTLADALLSRCVDLGVSVRTGATVTSISVAGGRVDGVRVDGSFVPADVVVSNVDAL
                     TLYRDLLPTPRRLSRLSDRSLAGFVLLLGVAGRTPGLAHHTVFFPSDYDAEFDAVFGGR
                     LAADPAVFVTVADDAAVRPAGHEAWFVLVNAPRHGVGPGAVDWNRPGLAAAYADRVLAV
                     LAARGVDVRDRVLFREVLTPASLEASAAAPGGAIYGTAGGLLRPANRGPLPGLFLVGGS
                     THPGGGLPMVALSARIVAGQIGPA"
     gene            complement(20205..21326)
                     /locus_tag="CHC05_RS20980"
                     /old_locus_tag="SAMN05421812_108184"
     CDS             complement(20205..21326)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475766.1"
                     /locus_tag="CHC05_RS20980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108184"
                     /product="glycosyltransferase family A protein"
                     /protein_id="WP_089251412.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6.5e-16,
                     bitscore: 52.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSALAWLPALLAGALAVHAAINARLLRRPSDAAFPEPVAVLLPVR
                     DEAARVEPCLRSLLGQRGVPLSILVLDDGSTDGTADVVRAVAGDDPRVRLLTGAPLPPG
                     WLGKPHACQQLADAADPAARVLAFVDADVVLSPSAVAGAAALLRSAGVGLLSPYPRIVV
                     GSWGERLVQPLLQWSWLTFLPLRALERSARPSLAAAGGQFLVVDRSAYLAAGGHAAVRS
                     SVLEDISLARAVKRSGGRIALADGSRVAECRMYSSWDSLVAGYTKSLWASFGSALGAAA
                     VVGLLLLVYVVPVLLTVFGLVTWSLPVVLAGCVAYALGVLGRVASAAATGGRWWPDALA
                     QPVSVLLFGWLVVRSYRLRRAGALRWRDRPVVL"
     gene            complement(21323..22081)
                     /locus_tag="CHC05_RS20985"
                     /old_locus_tag="SAMN05421812_108185"
     CDS             complement(21323..22081)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014457.1"
                     /locus_tag="CHC05_RS20985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108185"
                     /product="carotenoid biosynthesis protein"
                     /protein_id="WP_089251414.1"
                     /transl_table=11
                     /translation="MTRKLPWYGLGLLILAQICYPLTDDGARTAVTVTTVVLGYVLSVG
                     HAALTRGPRVAAVLVVVTTGGGLFVEAAGVASGAPFGEYAYSGALGPKIAGVPWVIPLA
                     WTWMAWPAWLAAVRLVRPTALRVGVAGVGLAAWDLFLDPQMVAEGYWTWSNPSPSLPGV
                     PDVPLGNYAGWLVVAILMMTVFSGLAGPAALVIGPDAPMYALYLWTYFSSILAHAAFLG
                     LSASAGWGALGMGLVALPLAVTLILHRVRT"
     gene            complement(22078..22632)
                     /locus_tag="CHC05_RS20990"
                     /old_locus_tag="SAMN05421812_108186"
     CDS             complement(22078..22632)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735112.1"
                     /locus_tag="CHC05_RS20990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108186"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_089251416.1"
                     /transl_table=11
                     /translation="MRLVPWKPDDLARRLDDVVAVYGEAMGYRPELMEARRGIIATHVR
                     RSGFRAVATLTTDGHLAGFGYGYVSGAGQWWHDQVRSALSEEHRKRWLTDCFEVVELHV
                     RPAAQGHGVGARQLRALLGMAPGATTLLSTPEADEQKSRAWRLYRSFEFVDVLRDFRFP
                     GDERAFAVLGRDLPVRAPSGE"
     gene            complement(22629..23324)
                     /locus_tag="CHC05_RS20995"
                     /old_locus_tag="SAMN05421812_108187"
     CDS             complement(22629..23324)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014441611.1"
                     /locus_tag="CHC05_RS20995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108187"
                     /product="monooxygenase"
                     /protein_id="WP_089251418.1"
                     /transl_table=11
                     /translation="MDTVVTLHVWRVPTRKIPHVLARMATDRARLRRHPGVRFAKLLGT
                     GTGTGFGPGDVDATRWAALLVHEKDKTPRAIESWTDLSTAHARVDLEPIASRGTWSGHQ
                     PFQKTQTTRTDGMVLALTRARLKPSRAATFWRAIPPVAASLRDAPGLLARFGVGEAPIG
                     WQGTVTVWRSTTDLVGFAYRQPEHRAAIARTAQVDWYAEELFARFAVCGIMGDRGVLGW
                     QQMTRSDPA"
     gene            complement(23359..23850)
                     /locus_tag="CHC05_RS21000"
                     /old_locus_tag="SAMN05421812_108188"
     CDS             complement(23359..23850)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018742850.1"
                     /locus_tag="CHC05_RS21000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421812_108188"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_089251420.1"
                     /transl_table=11
                     /translation="MQPHPNVRAVQDALDAAGARDAAGQPSQVRMLPAAAPTAAAAAEQ
                     LGVEVGQIANSLVFDADGAPLLVLTSGAHRVDTARVAKEHGIEKVRRANPDFVREHSGQ
                     VIGGVAPVHPGRPAMRTLVDTALFSFEEVWAAGGIAHAVFPITPAELERLTGGTVTDVA
                     "
     misc_feature    24022..24037
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.15"
                     /tool="antismash"
     misc_feature    complement(24023..24036)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.69"
                     /tool="antismash"
ORIGIN
        1 accagctccg cgagcggctc gcccaggtct gcgagggcca ggcgttcctg ctccagggcg
       61 gcgactgcgc cgagaccttc gacgccaaca ccgagagcca cctgctggcc aacgcccgca
      121 cgctgctgca gatggcggtc gtgctgacct acggcgcctc cctgccggtg gtcaaggtgg
      181 cccgggtcgc cgggcaatat acgaagcccc gctcgtcggc gaccgacgcg ctgggcctgc
      241 ccgcctaccg cggcgacatg atcaactcgc tggagacgac gccgggcgcg cgggtggccg
      301 atccgcagcg gatgatccgg gcgtacgcga actcggccgc cgcgatgaac atgctgcgcg
      361 cgtacctgtc cggcgggctc gccgacctgc acgccgtaca cgactggaac aagggtttcg
      421 tccgtgagtc gcccgccggc gagcgctacg aggcgatcgc ccgcgagatc gaccgggcgc
      481 tggcgttcat ccgggcctgc ggcatgaccg acgacgaggc gctgcgcacg gtcaccctct
      541 actgctcgca cgaggcgctg gccctggaat acgaccgggc gttgacccgg gtctccgaca
      601 gcaaggcgta cgggctgtcg gggcacttcc tgtggatcgg tgagcggacc cggcgcatcg
      661 acggcgcgca cgtcgacttc ctgtcgcggc tcgtcaaccc gatcggcgtg aagctcggcc
      721 cgaccaccac ccccgagcag gcgatcgagc tgtgcgagaa gctcaacccg ggcaacgtgc
      781 cggggcggct caccctggtc gcccggatgg gcaatcaccg ggtacgcgac gcgctggccc
      841 cgatcgtcga gaaggtcacc gccgccgggg ccaaggtggt ctggcagtgc gacccgatgc
      901 acggcaacac ccacgagtcg tccaacggct acaagacccg gcacttcgac cggatcgtcg
      961 acgaggtgct gggctacttc gaggtgcatc gcgggctggg cacccacccc ggtggcctgc
     1021 acgtcgagct gaccggcgaa gacgtgaccg aatgcctcgg cggcgcccag ggcatcgaag
     1081 accttgacct gcccgaccgg tacgaaacgg catgtgaccc ccggctgaac acccagcagt
     1141 cgctggagtt ggccttcctc gttgcggaga tgctgcgtgg ctgagctcgt ggacctgcgg
     1201 tccgacaccg tcacccaacc gtccgaaggc atgcgggccg cgatggcgtc cgcggtcgtc
     1261 ggcgacgacg tctacggcga ggacccgacg gtcaacgcct tggaggcgtc ggtcgccgcg
     1321 ctgttcgggc acgaggcggc gctgttcgcg ccgaccggct cgatggccaa ccagatcgcc
     1381 atccagctat ccgtgccgcc gggcgaggag ctgctctgcg acggcgacgc gcacgtggtg
     1441 acctacgaga tcggcgcggc ggcggcgatc ggcggcgtgt ccacccgcac ctggacgccc
     1501 gtcggcggtg acatcgaccc cgacgtggtg atcgacatga tccgtcccgc cggctaccac
     1561 gcggtgccga cgcgggccat cgccgtcgag cagacccaca accggggtgg cggcggggtc
     1621 atcccgttgt ccacgttgga ggccctgcgg gccgcgtcca ccgcggccgg agtggcactg
     1681 cactgcgacg gcgcgcggat ctggcacgcc cacgtcgccg acggggtgcc gctgcggacc
     1741 tacggcgggc tcttcgacac cctttccgtc tgcctctcca agggcctcgg tgccccggtc
     1801 ggctcgctgg tcgtctcgac ggcggccaac atcgagcggg cccgggtgat ccgcaagcgg
     1861 atgggcggtg gcatgcgcca ggcgggggtg ctggcggcgg ccggcgcgta cgccttggaa
     1921 cacaacatcg cccggctggc cgacgaccac gcgaaggcgg cccggctggc ggaggccctg
     1981 gccccgttcg gcgtggtggc cggtgccgtg cgcaccaacc tcgtcccgct cgacctgcgc
     2041 aagtcgccgc tcgacgcgca cgccttggcg gcggccgccc gtgagcgcgg cgtgctggtc
     2101 tcggtgctcg ggccgcaggt ggcccgactc gtcacccaca tggacgtcga cgacgccgcg
     2161 atcgaccacg ccgtcgacgt cctcccaaag atctttcgcg attgacaggt tcgcgtgctt
     2221 tgctgagtag ttgaccggtc cgcaccgggc cggctcggct gcgcgggggt tggcatggcc
     2281 aacgcgggcc tgtggcggtg gtccgcctgg gcctttctgg cggtcgcggg cgctttggtg
     2341 ctcgcgacgc tggcgggcgc tgcgccggtg ctgagcgcgg tcgccgccgc ggcggcgttc
     2401 ctggtggccg gagtgaccct ggtcgtccgc cgaccgcccc gcgtggcggc ctggggctcg
     2461 ctgacggtgg cgtcgggatc ggtggtgttc cggatctacg ccgcggtgac cggtccggtg
     2521 atggtgggcg gccgcagcgg cgggctggcc ggtggggaca tccgggccct ggtgctctat
     2581 ccggcgctcg cggtcggact ggtcctgctg ggtggcaccg gagccgccgc cgacctgacg
     2641 gacagcctcg acgcctcggt cgtcaccctc ggggtgttcg tgctgctgtg gctgttcctg
     2701 ctgcacggcc agatcgttcc gaccggcgcc cggctggtgg tgtccgggct gcggcccgtc
     2761 gggatctcgg tcgtcctcgg cgcgctggtc cggctgttgt tcgtcgtgcg tccccgcgct
     2821 ccgaccatca ggttcgtggc ggtcggggtc gtcctggccc tggtcggcgc gatcgggctg
     2881 gtggcccggc aggccggcta cgacgtcgac ggccggctct tcggcggtgg gatcttcgcc
     2941 gtcgggttcg ccgtcctgat cgccgtcgcg ctgctgcgtc cctcctcggc cgaggtgccg
     3001 gcgcgccggg gcgagggcct cccggccgcc cggctcagcc gcgggcggcc gcgctgttcg
     3061 tcgcgctgac gctgctcggc ccgctggcct gggtgaccgc agtggccttc gggcagttca
     3121 accccggttc tccggaagac ttcgggccgc cggtgctggc cgccgcgttg atcgcgctgc
     3181 tgctcctgtg gcggctgtcg ctgctggccc gcgtggcgga cgcgccgagg agctcggggt
     3241 ggtggtcggt gagctgcgcg ggctccaggc ggagctcgcc taccgcgcgt cgcacgaccc
     3301 gctgaccggc ctgtccaacc ggtcggtgct catggaacgg ctgaccgccc tcccgccccg
     3361 gcggtcacac gcgttgctgc tggtcgacct cgacgggttc aaggagatca acgactcgct
     3421 cggccatccc accggcgacg agctgctggt ctccctcggc cgccggctga cctcgctggc
     3481 gccgccgggc agcacgctcg tccggctggg cggcgacgag ttcgccctgc tgctgccgag
     3541 cacggcggag gccggcgggc tggccgtcgg cgggacgatc tgcgcccggc tgcgggtgcc
     3601 gtacccgtcc acccacggcg agctggccgt cagcgccagc gtcggggtga cggccgggcc
     3661 gctggccgcg cgctccccgg ccgacctgct gcgcgaggcc gacctggcgc tgtacgcggc
     3721 caaggcggcg ggcaaggacc gagccgcggc gtaccggcct gacctggccc caccgggtct
     3781 aggtgtccaa ggtcgacagt aggtctgtgc cgcgctcggt gaggcggtag acgaccgcgc
     3841 ggccgactcg ggcgccggcc accacgcccg cgtcgcggag cacggccagg tgcgtgctca
     3901 ccgtgcccaa cgagacgtcc agggtgtacg cgagctgcgt gctggtcgcc gcccggcgca
     3961 gctcgcggac cacccgcgcc cggcccggtc ccagcagcga gccgagcggg tccccggccg
     4021 ggccggccac ctccgccgcc gggccgcggg ccgggtagac cagcgcgtag agcggcgggc
     4081 gctcgcaggt ccacgagccg acgccggccg tcttcggcac gaacaccaga ccctcgtcgg
     4141 tgatccagcg gtcggggtag tcctgctcgc tgaaccggat cgcgtcgtcg ccgacccaga
     4201 cggagtgccg ggtcatgttc ttgaccgctt ccttccagcc gtacgcggcg agcaggcccg
     4261 cgcggtgcat gatgtcgcgt tcgagcagcg cccggcggcg cggccagtcc ttggcgacgt
     4321 gccgccgcca gccctcggcc agcacttctg ccgtcctggg cccgaggtcc gctccgctca
     4381 gccagcgggt gtcctgtggc tcccagctct ttgtgaccgc ggtggcaacg gtcgcgcgga
     4441 tctcgtcgtc ggtgaaggtc gctacttctt tgagctcgtc gcgtagccgg gtcctggtgc
     4501 cgccggtggg tgggacggcg accatgtccg gcagccactt ggtggccgag accagcgcga
     4561 gcaggccggc cgcgaacggg tcgccggcca gccatttctg gaagccgggc tggttcgcgg
     4621 tgtgccagct tttcagccat ggctccggcg ccggtcggtg caacgcgatc agcgagccca
     4681 gcgtctcggc gagcggggac agcgcgaagc ggcaacgggc cagcgcggtg ggggagagcc
     4741 tcaggagggt catgtttacg cctttcgccg caaggttagc ggccgggcgg gcgtggccgg
     4801 aatgctcccg tggtgctgtt cacccctgga ttccgcgcct tctatctcgg tcggctggtg
     4861 tcgctcgccg gcagcgcgat gaccccgatc gcgctcgcct tcgccgtgct cgacgccagc
     4921 ggccggccct ccgacctcgg catcgtgctg gcctgccaaa tcgtgccgca cctggccctg
     4981 ctgctggtcg gaggcgtcgt cgcggaccgg ctcccgcgcc tcgcggtgct ggtcgcggcc
     5041 aacctgggcg cgggcctgac ccagggcggg atcgcgctgg tgctgatcag cggcgcgtat
     5101 cgcctgtggc tggtgaccgg gctcgcgctg ctggccgggg cctgggaggc gttcacctcg
     5161 cccgcgctgc gcggcatcgt gccggagatc gtctcgacgg accacctgca gcgggccaac
     5221 tcgttgctgt cggcgacccg cagcgcggtg ctgatcgtcg gaccgaccgt gtccgggctg
     5281 gtcgtggtcg ccgccggggg cggctgggcg atcgccgtcg acgcggtcag cttcgtcgcg
     5341 gcggcggcct tcctgtcgcg gctgccccgg gtcgctccgg ctccggccgc cggggcgcgt
     5401 ctgctgcacg acatccggga cggctggcgg gtgttcgtcg cgatcccgtg ggtgtggccg
     5461 gtcgcggtcg cgtacgcggt gatcaatctc gtgaacgtcg gtccctggca gatcctcggg
     5521 cccgccctga cccagcagcg ctcgggcgag gccgcctggg gcatggtgct cagcgtgcgg
     5581 gccgtcgggc tgctggcgat gagcgccgtg atgtacaagc tgacgctgcg ccgcccgctg
     5641 cgcttcggcc ggctggccgg cgcgctcggc gcctgctcac tgctggcgct cgggctcggc
     5701 ctgcacccgg tcgcgctggc ggcgtgcgcg ttcctcggcg gggtgggctt cgcggcgtcg
     5761 gggatcacct gggagagcgc ggtgcagcag cacgtcccgt cggcccacct cggccgcgtc
     5821 tcgtcgatcg acgacctgct gtcgttcgcg gcgatcccgg ccggccagct cctggtcggc
     5881 ccggccgcgg ccgcctgggg cggcgcgcgg gtggcgctgg cctgcggggt cgtattcgcg
     5941 gtggcggcgc tggccccgct cggcgtgcgg gcggtccgtg gcctaggcca gtaacccgcg
     6001 tagcgtcgcg atgtccgcgg cgtggccttc gtgggccttg ccggacgggg tctcgacgat
     6061 gatcggcagg ccctgggtcg acgggtgccg gagcagctcg gcgaaggcgg ccgtgccgat
     6121 cgtgcccttg ccgatcgtct cgtgccggtc ccgcagcgag ccgcaggtgt ccttcgagtc
     6181 gttggcgtgc accagcttga gccggcccgc accgaccgtc gcggtcagca ggtccagggt
     6241 cgccgtcatc ccgccgggcc ccgccaggtc gtggcccgcg gcccaggcgt ggcaggtgtc
     6301 gaagcacacc ccgaggcggg ggtggtggtc gacggcgtcg aagtactccg tcaggtgctc
     6361 gacccgcgac gccagcgacc ggcctccgcc cgcgctcggc tcgacgagca gcagcggccc
     6421 gtcctggtcg agcagcggca gcaacgcctc gcggacctgc ttgagcgcgg cgtcgtagtg
     6481 ctccgggtcg accgagctgc cggcgtggaa gaccaccgcg cgggctccga tcgccgtgcc
     6541 ccgggtcagc gcgtgcgcca gcgtcgccgt ggaccgctcg accgtctccg gcgtcggcga
     6601 gccgaggttg accagcagcg acgcgtgcac gtagaccggc acgtcccgct cttcacaccc
     6661 ggcgcggaac agcgcgtcct ggtccgggtt gccgggcggc agcgcccagc cgcgcgagtt
     6721 ggacacgtag acctgcgcgg cccgggagcc ggccgcgtcg aggtagggca gcgcggtctt
     6781 cgcgatgccc ccacccgacg gtgtgtgcga gccgatcagt tgcaaaacag gacgacctgg
     6841 ctctgcggct cgaccggcgt gttctcgttg ggctgctgcg cgaacaccgt gccgttcggg
     6901 ttgagctgcg ggttgggcgt caggcccatc ccctgcacct gctgcaccgc ctgctggcag
     6961 ggcaggccga tcagccgggg cacgaccacc tgcggcgggc cctcgctgac ctcgagctcg
     7021 atcttcgcgc ccggctcgac cccggccccg tcgctcggcg tctgcttggt gacggtgtcg
     7081 cggggctggt cggacttctt gtacgagatc agcggctcca gcccgagcgc gatcagctcg
     7141 ttgcgggcct cgttgacgtt cttgccgacc acgcgcggca ccgacagcgg cgccttgccc
     7201 ttgctgacga acacggtgac cttgtcgccg ggcttggtct cggtgtccac cggcgggtcg
     7261 gtcgcgacca cggtgccctt gggcaggttg tcgtcgtagc ggtcggcgcc cttgacgatc
     7321 tggagcttgc gctcctggag ctcggtggtg gccagctgga gcgtcatgcc ggccacgtcc
     7381 gggacggtgt agcgctcggc gcccagcgag agcaccagcg tgatcgtgcc gcccttgagg
     7441 atccggccgg ccgccgcggg ctgctggctg agcacgacgt ccttctcgac cgtctcgtcg
     7501 aactggggct cgccgtaggc gatcgtgaag ccgccccgcg tcgcctgctg ctcggcggcg
     7561 gccttggtca tcgcggcgag ctgcggggcg accgtgtagc ggcccatgcc ccaccaccag
     7621 ccgctgatcg cgaagatcag gccgaccagc acgatcgagg cggccaccgc catccggcca
     7681 cgcgggttcg ccatgaccat gcggtagcgc tcggcgagct tgcccttccc gcccgggtcg
     7741 tcgtcatagt cgtcgtacgc gggctccggc gcccggcgcc ggccgctggg cggcggctcg
     7801 gcctggccgg gcaggcgcgc ccaggtcggc cgggcgggct ccgcggtggg tccggtgacc
     7861 cgggggatcg tcacggtgcg gtcggagacc tgccgcagca gggcggtgtt ggcgttggcc
     7921 gcaccgaggt cgtcgcgggc gacctggacc gcggagagga acgcgccggc gtcggtcggc
     7981 cgggcctgcg ggtcgcgccg agtggcgcgg gagaccagct cgtcgacgac cggcgggatg
     8041 ccgggcacca gcgtcgaggg cgccgggacg tcccggtcaa cgtgctgcca ggcgacctcg
     8101 accggctggg cgccgtcgta ggggacccgg ccggtgagca tctcgaacag cacgatgccg
     8161 gcggagtaga cgtcgctgcg cgggtcggcg cggccgtcgg tgacgagctc cggcgcgacg
     8221 taggcgaccg tggccatcag ctggccaccg tcgccgtcgg tggcgctggc ctcgacggcg
     8281 cgagccagac cgaagtcggc caccttgacc acgctgtcga ccaggttgcc cggcccgccg
     8341 ctgggcgcct cggcgacgag cacgttctcc ggcttgacgt cgcggtgcac gaggccggcg
     8401 cggtgggcgg cggagatcgc cgcgagcatc tgctcgagga tcgccagcgc ctcgcccggg
     8461 ttgagccggc gccgctgggc cagcacgtca cgcagggtgt ggccgcgcac gtactccatg
     8521 accaggtagg gcagcccggc gtggcggccc tggtcgtaga cggcgaccac gttcgggtga
     8581 gtcagtcgcg cgatcgtctt ggcctcgtcg gtgaaccgtt cgaggaactc cggatcgcgc
     8641 gcctgcgccg gatgaatgat cttcagggcg accgtgcgct cgaggcgctc gtcggtcgcg
     8701 gtgtagacgg tcgccatgcc gccacgggcc acccggccac ggatgcggta acgcccgtcg
     8761 accagtgtgc ccagcagcga gtcagcgacc tggatgtcca tcggcaggca gtctatgtgc
     8821 ccgcccgggc ggcgcgacac agccgtgccg gcaaagtcac cgctaacccc gcaatcaggg
     8881 gttttcgtcc tggtcatggc ggtggtgccg gtgccgtttc cgcccctcgt cggtgggttc
     8941 gtcgcccggt tcggaggcgc tgggcgtcgg gctgggggtc gcggacggct cgtcggtcgc
     9001 ggcgggggtc ggcgtcgggc tgggggtcgg cgtcggcgtt tctgtctgtg gtggggcgtc
     9061 gtcggagtct tccggcaccg gggctccgcg cggcagctcc ggtttcgggg cgggtcctgc
     9121 gccgcccggg acaccgtcgt gcgtatccga tgaaccggcg ccaccggccg aggcctggcg
     9181 gccggcgacg gtgagcgggc caccctgccg ggcgatccgc acgctctggt ccggcctcgc
     9241 gtccgcgtcc gtgcgttggc cggtgccggc ggcgccggcg acgacggacg ccggcttctc
     9301 gccctcggcc ttctggcctg gctccagcag cgcgccgagg ccgttgacga ccgcgaagta
     9361 cgtgccgatc gcgccgacca ggctgacgag gacgaacccg ccggtggccc gcagccttct
     9421 cggcggccgg ttctgttcag ggaagatcag ctcggtggtc tcctcgccgt cggtgcggcg
     9481 cgtcttcgcc ctgctgaggt cgtactggat cgaccgccac gcgccctcga gctccttgcg
     9541 cacgccccgc caggtcgtca cgggagttcc ctccgagatg ttcggccggt acggcgatac
     9601 cccgtaccgg gtggttcggt ggtgtcacgc cctgtcggcg tggcaatgtg agcgggtgac
     9661 cgaaaccgtt cccgctcagt ggctgccttt gcccgacgtg gcggagcgcc tcgacgtgtc
     9721 gatcagcaag gtgcaccaga tggtccgcga cggctcgctg ctcgcggtcc ggcgcgacgg
     9781 cgtcctgcgg gtgccggccg agctggtggc caaccgcacc gtgctcaagc acctgccagg
     9841 cgtcatcacg ttgctgcacg acgctgggta caacgacgaa gagtgcctgc ggtggctcta
     9901 cgcgaccgac gagacgttgc cgggctaccc cgcggccgct ctcggcggtg acaaggcgac
     9961 cgaggtgaag cgccgagccc aggcgttggg cttctaggag ttgcgcttcg tctacctggc
    10021 ggtcctggtg ggctgcctgg ccggtgcact ctggctggaa ccggccctgc gggtcaacgt
    10081 cctgcgccgc tggcgccgcc tgctgttgac cctggtgccg gtgatggcgg tgttcgcggc
    10141 ctgggacatc ttggcgatcg cggccggcca ctggtcgttc gacccgcgcc agacgacggg
    10201 cgtggtgctg cccggtgggc tgccgctcga cgagctgctg ttcttcctgg tggtgccgct
    10261 gtgcagcatc ctggggttcg aggccgtccg agcggtgctg cggctgccgg cgggcgacga
    10321 gcgcccgtga cctacacgac ggcggccctg gtcggagccc tcctggcgct ggtcctcgac
    10381 ctggcggtgc tgcggacggg gttggtacgg cggcgggtgt tctgggccac gtacccgatc
    10441 atcgtgttct tccagctctt gtccaacggg gtgctgacgg gccgcgacat cgtccgctac
    10501 gacccgtcgg cgatcgtcgg ggtgcggctc gtgtacgcgc ccgtcgagga tctggtcttc
    10561 ggcttcgcgc tggtgttgtc gacgttgtcg ctgtgggtgt ggtgggggcg gcagggagtt
    10621 cagcgggagc cggcggcggg gacggggtcg tcctggttgc tccggcggtt gcggaagcgg
    10681 aagtaggcca gggcgccacc gacgaggatc gccacgtcga cgatggctcc ggggagtttg
    10741 gtcagcaccg gcagcccgag gccgttggga agggccaacg ccgtgaccac gatcgcggcg
    10801 gtcgcgaggg cggttctggt ctttcctggt ggggtggcgc aggcgaggac ggccagcgga
    10861 acgagggcat accaggggta gaaaaccggc agcaggacag cggcggcgac gagcgcccac
    10921 ccacaagccg cgacaacctc ccgacgggtc gcagttcctg ctcgacctcg cgtggcggcg
    10981 tcattgggtt cgagttcggc gtccctgggg tcgcgcccgg tcggtggtcc ggagtgcgcg
    11041 gcgacacggc tggtgtgtgg ctcggagtcc ggggtgacac ggctggtttc ttgttgggcc
    11101 tgcgcggcgg cgccgctggg ttcgtgttcg gtgtgtgagg tgagccggtt ggttgctggc
    11161 tgggcttcag cgctggtggc gttgggttgg tgttctgtgt gtgaggcgac gcggttggtt
    11221 gctggctggg cgtcggcgct ggcggtgttg ggttggtgtt ctgtgtgtga ggtgacgcgg
    11281 ctggttgctg gctggacgtc ggaggtggcg gcgctgggtc ggcccggttg cctgggcgca
    11341 gggctcgcgt cggcttccgt gctggcgcgg cgcggggccg ggagtgcgta ggccgggtgg
    11401 agggcgagcg tggcgcgcag cgcgcgccag cagaggccga gcccgatgac ggcgagcgca
    11461 gcgatgccgc aggcgcgggc gacgtcgacc gtcgcgtcga cggcgccggg gtggccggcc
    11521 gcgcggaaca cgtagccgat cgccattccg atgccggtcg gcagcgacgt ccactgcacg
    11581 aggctgccgg tgtcggagag ggcgccgacc cagccgaggt cgagcccggt ggccagaccg
    11641 gcggcggcga acaccagcgc accggtcccg gtcacggtga gcccggcgag cgcgatggtg
    11701 acccacggtg gtgtgccgcg gcgcagccgc caaccagcga ccagcaggac aacgaacggg
    11761 agggccagga tcgcggtcac cttgaccccg accgcgagcc caaggaaggc cccggcacct
    11821 accgcggatc cccacgacat gccccggtag gcctgagatg gggcccgcac cggcttgccg
    11881 ttccaggtcg cgtcgctggt ctcggtcggg ttgctggtcc aggtggcgtt gctggtcccg
    11941 gtcggctcgc cgttccaggt cgcgtggctg gtctcggtcg ggttgctggt ccaggtggcg
    12001 ttgctggtcc cggtcggctc gccgctccag gtcgcgttgc tggtcccggc cgggtacccg
    12061 gtctcggtct cgatgtcggt cgggcttccg gcctcgattg ccggtccgaa cctgctcctc
    12121 gtttcagccg cgagggcgcc gtgcctggag acagagccgg gcgtgaccgc atcccctgtc
    12181 gacacgcgcg ccgcgtgtgg ggactgttct ccggtttccc taccgggatc gttcgacctg
    12241 gtggtcgcgg gtccggagac cgccgcgggc acatcgcgcg cgggtgtggc gaggaccacc
    12301 gtggccggac cgcgagacgc gacggccggt acggcgaccg ccagggcggc gacgagcagg
    12361 ccggccgtga gggcgtcgtt gtgggcgccg gagacgaggt ggaccgcgac gagcggcgag
    12421 agcagcccga gccaccgcgc ggattccggg cggacgccca cggcgttggc cagccgaccc
    12481 gcgtacacgg cgatcaacac accaccgacc agcgcgacga gccggagcac ggtgaccgcc
    12541 accagcagtc ggtggtcggc gggcccgcca accgcgcggg cgacggcggc ggccgcaccg
    12601 gacagggcga tgccaaccgg gccgtaaggc gccggcgtgt gctgccagag gtccggcacc
    12661 gcgttcgacc agaggcatcc gccgtcggcc gcaccgatcg cgtacgggtc cagcccggat
    12721 cgccagatct cgccctggca ggcataggag tagacgtcgc ggctggccag cggcggtgcg
    12781 agcagcagcg gcagggccca gagcgcgccc gtggtgatca accagcggct gccgaggccg
    12841 cccaaccgcg aaccgatccg ccaccacgca ccggacacga tcgccagccc gaccacccac
    12901 gcggcgaggc cccaccagaa gccggcgccg ggcgtgccgg ggccacgcag gccgagtccg
    12961 gggtcccgcc ccggcaaggc ccccgcttca tatgccccgg cggcgacaac ggcgaccccg
    13021 acaagcccgg tgacgcgcag accccacggg ctgtccaggc cacgcacgcc atcgatgatc
    13081 ccacgccggt cgcggaccgc aacgacgctg gcctccccgg gcgccgggcc gccggggcgg
    13141 ttggcctccc cggacgggcc gggcgggacg gctggcgtcc cagacctggg accgatgcgg
    13201 cggttggcct ctcggacggg gcccggctgg gtggttggcc tctcggacgg ggccggctgg
    13261 gcggctggcg tcggacctgg ggccggtggg gcggttggcc ctcggacggg gccggctggg
    13321 cggctggcgt cacggacccg gcgccggtgg ggcggttgac cttcccgcac gacgggcggc
    13381 tggcgtcctg ggcctggggc cggcggggcg gccgggtcag tcggtgcggg tggtggcggc
    13441 gtgggcgagg tcgatcaagg ccgcccgggc ctcgccgtcg atcggtgccg actcgatcgc
    13501 ggccagcgcc gcgtccagca acacgccgat ccggcgttcc gtccgttcgg cggcgccgct
    13561 ggccacgatg acctcgcgga ggtgggcgat gccggccgcg tcgaggtcgg gcgagccgag
    13621 caggcgctgc aggtcgcggc gaccggactc gtcggccgcc tcgagggtgg ccgccaccag
    13681 aaaggtgcgc ttgccctcgc ggaggtcgtc gccggccggt ttgccggtct gcgccgggtc
    13741 gccgaacacg cccaggaggt cgtcgcgcag ctggaaggcc tcgccgagcg gcaacccgta
    13801 gcccgagtac gcggcctcga cctcagccgg tgcggcggcc agtgcggcgc cgagcagcag
    13861 cgggcgctcg accgtgtact tcgccgactt caggcgtgcg accttgccgg cgcgctcgac
    13921 ggatgtgtcg ccggtcgcct gggtcaggac gtccaggtac tggccgatcg tcacctccgt
    13981 gcgcatcgcg tcgaagaccg ggcgggcgcg ggagagcgcc gccgggtcaa ggccgcccgc
    14041 gtgcaacagc tcgtcggacc agaccaggca gaggtcaccg agcagcacgg cagcggagtc
    14101 gccgaagccg tcggcgtcgc ctgtccagcc gtgggcccgg tgccgggtcg cgaacctgcg
    14161 gtgcaccgcg ggctcgcccc gccgggtgtc ggagcggtcg atcaggtcgt cgtggatcaa
    14221 cgcgctggcc tggaccagct ccaacgcggc gagggctttc acgacctggt cggagtcgtt
    14281 gccgccggca ccgcggaacc cccagtagcc gaaggccggc cgcagccgct tgccaccccg
    14341 cagcacgaaa ccctcgatcg cgtcggcgac gggcgccagg gcgctgtcga cctcggccat
    14401 ccacgcccgc cggtcggcca ggaaccacgc caacgatttg tcgacccgct gccgcaggcc
    14461 ggtccggtcg gtcgcgggca ggttcggggc ggcaatcggc cagcctggat cggcgggaac
    14521 cgcgccggcg gcgtcggaag ggctcgtcgg ctcggtcacg ccacgacgct agggtcaatc
    14581 cgccggaacg acaaccggag cgctcaccgc cgggctgcgg atcaccgtcg tggcccgccg
    14641 gcggaccgcg accgggcccc cacccagcgc ccacccgagc cgggccaggc ctcgcgccag
    14701 cgcccaccca agccaggcgc ggtgcgacgc ccacccgagc ccggcccggc cccgggccgg
    14761 agcccaggtc acgccgcgcc gaggccggac cccaggaccc gtcagtcatc gccggccacc
    14821 cgatgacctc cgaccggctc gtcacgcagc ggccgtggca ggtagggccg cgccgccacc
    14881 aacaggtcgg cgtagtcacg tgcggcgggc agccgggcat gcggggcgat tcggtcgccg
    14941 aaggcggtga gcaggtcgag cgcccgcgtc gaacccgagc ggatcgtgtc gagcaccgcc
    15001 gcgccggcga ccagcaacgc gccctcggcc tcgccggtgt cgagccgggc ccgggccagc
    15061 caggccttgt cgagcgcgcc ggtgcgcggc tgaccggagc gggccgcggc ccgcgtcagc
    15121 agcgggagcg cgcggttggg tcggccgagc acgaccaggc agcgaccggc cagcgcgtcg
    15181 agctcaccct cgtcgagcca gtagagccag ggcggatcgt gctccgcggc ccgtcgctcg
    15241 gtggcccgct gcgcggcgac cagcgccgcc tcggcggcac cgcgtaaccc ggccgccgcc
    15301 gccgcgaacg cgatccggtg cagcagcagc gcccgccccg acgccgacag ggcccggcgt
    15361 gaccccgcgt aggcggtgcg ggccaacaac aacgccggcg ccgggtcgcc cgaaccggcc
    15421 aacaggtgac tggccgagcc tagtacgtgg ccggcgagcg gccggtcacc cgcggccgcc
    15481 gccgcgccca gcgccgcccg ataagcggac agcgcgccga gcggatcgcc cgcgtcggcc
    15541 agcgtccagc cgcggagctg ggcgacctcg gcccgcagcc gggccgctct gcgggtcagg
    15601 gtggcgccgg ccggcggcgt cgtcgcctgg gcggtggctg ccccgagccg ctgcaccgcg
    15661 ctggccaggt cggccccgcc gagcacgtcg tcgaggcggc gggccgcgac caaccgggcg
    15721 gtcacctcgg cgacggtcgg ccgttcgcac caggcggtcg ccggaggagc ggctcgcggc
    15781 ggcccgatca gcggcggtgg gtcgccggcg agccacgtgt gcgcgagccc gagcaggtcg
    15841 agcccgaccc ggtcacggct ctccggccgc ccggggccgg cctgcccggg cgcggccagg
    15901 cggtggcgca accggctgcg ctcggccgcg gccgcgaggc cgtcgaccgg cgtgtcgagc
    15961 acagcggcga gccaaccgag ccagaagtcg gccggcagtc gatcctcgcg ctcccagcgg
    16021 ctgacctcgt ggcgggtcac ggtcgggctg ccggaggcgg cgcagagctg ctcggccagc
    16081 cggagctggc tccagccccg gcgtaaccgc agctgagcca ggtagggacc gaacggcgga
    16141 cgcggaccgg ccgcgtcgaa cgggtgcggt ggcgacgcgg acatcatgga ccctccccga
    16201 agcagcggtg cacgcctgtg gcccccggat gccgcgaacg gcaccccacg cgccgaccaa
    16261 cggaccgtgg tgtcggcccg cggcgcgtag aacatatgta cccctcgggt gcgacgtttt
    16321 cccgtcccca tcccgtcggc aacgccgtca ccagcgcgaa cgcgcgttat ccacaggcgc
    16381 ccggtgcggc gaccagcaag accacccagc cggtacgctc gacccgtggc gctcggactc
    16441 ccctcgatcc ttccgggatc gcaaccatcg atcggtgacc tgatccgcga ggcaggcccg
    16501 acgttctcgt tcgagttctt cccgcccaag acacccgaag gcgaggtgca gctgtggcgg
    16561 gcgatccgcg agctcgagcc gctacacccg tccttcgtct cgatcaccta cggcgcgggc
    16621 ggcaccaccc gcgacaccac ggtgtcggtc accgagcggg tcgcgaccga gacgacgctg
    16681 cttccgatgg cccacctgac cgccgtcaac cactcggtcg ccgagctacg caacgtgatc
    16741 ggccggctgg ccgcggccgg catccgcaac atcctcgcgg tgcgcggcga cccgcccggc
    16801 aaccccaacg gcgagtgggt gcgccacccg gagggcgtcg actacgccga agacctggtc
    16861 aagatcattc gcgagtcggg tgacttctgc gtaggcgtcg cggcgttccc gtacaagcac
    16921 ccgcgctcgg ctgacatcgc cagcgacacc gacttcttca tccagaagtg ccgcgccggc
    16981 gccgacttcg cgatcaccca gatgttcttc gacggagacg actacctacg cctgcgcgac
    17041 cgcgtggccg ccgcaggctg cgacaccccg atcctgcccg gcgtgatgcc ggtgacccgg
    17101 atgagcacca tcgcccgctc cgagcagctg tccggtgcgc cgttcccgcc cgcgctggcc
    17161 gagcagttcg cccgggtcgc cgacgacgcc gacgcggtgc gcaagctcgg catcgagcag
    17221 gccagcgaga tgtgcgcccg cctgctcgcc gagggcgtgc cgggcatcca cttcatcacc
    17281 ctcaaccggt caacggcgac ccgcgaggta tggcagcacc tacgggtcga cgccggcgtg
    17341 tgacctcgac cgccgatgga cggttgagct gacgtgggca cacggctggg ttggcacgac
    17401 tacgcgtccc gatgggcggc actgcacggc ggcttcgacc cgagacaggc gggcacggtc
    17461 gtccgaggct gggtccgtct ctcctacgag atcggttccc gcctcggccg cctaaggatc
    17521 tcgccgacgg cggtcaccac ggtcggcctg ggcctgtgcg cggccacgcc gatcgccgcc
    17581 acccgggccc cggagggcct ggtcacggcc gcgatcctgg tcatcctggc cgccgtggcc
    17641 gacagcgtcg acggcgcggt tgccgtggcc accgaccgca cgacccgcct gggctacgtc
    17701 tacgactcgg tcgccgaccg cctgggcgag atctgctggc tgaccgcctt ctgggtagcc
    17761 ggcgcccccg caccgctggt cttcaccgcg ggcgcgctgt cctggctgca cgagtacatc
    17821 cgcgcccggg ccaccgccgc cggcatgacc gagatcggca cggtcaccgt cggcgaacgc
    17881 ccgagccgcg tcagcgtcac gacggtcgcc ttcctcgccg cggccggtgc cggcgccgtc
    17941 aaccgcgacc tgacgccggg caccctgacc gtctttctgg cgatctggat cctcctggcc
    18001 accttcggcc tggcccaact tctgcgagcg gtccgccgcc tcctgcgctg acacccgacg
    18061 accgctccac taccgggccc gcgccacaca accgacaagg cgcgaacaac gacgacatcc
    18121 ctcgtgcgag ggagcgagcc ggtcaggtca ggccggcgcg tttcaggatg tcgatgatga
    18181 cggttgactt ctggttcgcg tactcggcca tgtaggtcac gcccgattgg gctattcggc
    18241 gtttctccgc cgcgtagcgc gatcggtctt ccgggtgcgt gcgcagccag tcgcgcagga
    18301 tcaggtggcg taggtgttcg tcgcagtccg gcgggaagac gtgtacgttg cacggcgggt
    18361 cgaagccgtg cagcgcccgg cgttcgtacc agtccggctc ccggaggcgc agcacatagc
    18421 ccgccgacga cagtgccggc agataggcgt cctcgtcgcg cgggtctgtg acgaccacgt
    18481 cgatgtcgat ccggaacttc gccgccatcc ccggcaccgc ggtcgacccg acatggtcga
    18541 ccgccaacgc caccaggccc agcgcggcgc ggatccgggt ggcgtgccgg gcatacaaca
    18601 ggggccagac cgggtcgtac gccgagatca taatcggcgc cgtcaaccgg ggtgggtcgc
    18661 ccacgttccg tgcgcgcagc cactcctccg tgaccggcgg tgcgggtgcg ggcagcggcg
    18721 gcatgcgcat cgacaagagc ctacgccggg ccgatctgcc ccgcgacgat ccgcgccgac
    18781 agcgccacca tcggcagccc gccgcccgga tgggtcgagc cgccgaccag gaacagcccc
    18841 ggaagcggcc cgcggttggc cggccgcagc aacccgccgg cggtcccgta gatcgcccca
    18901 cccggcgccg cggccgacgc ctccagcgac gccggcgtca gcacctcccg gaacagcacc
    18961 cggtcgcgga cgtcgacgcc gcgcgcggcg agcaccgcca acacgcggtc cgcgtacgcc
    19021 gccgccagcc ccggcctgtt ccagtcgacc gcacccggcc cgacaccgtg ccgcggcgcg
    19081 ttgaccagca cgaaccacgc ctcgtggccc gccgggcgga ccgccgcgtc gtcggcgacg
    19141 gtgacgaaca ccgcggggtc ggccgcgagc cgcccaccga acaccgcgtc gaactccgcg
    19201 tcgtagtcgg acgggaagaa caccgtgtgg tgcgccaacc caggcgtgcg gccggcgacc
    19261 ccgagcagca gcacgaaacc cgccaggctc cggtcggaca gccgggacag ccggcgcggc
    19321 gtcggcagca ggtcccggta cagggtcagc gcatccacgt tggacaccac cacgtcggcc
    19381 ggcacgaacg acccgtcgac ccgtacgccg tcgacccgac cgccggccac cgagatcgag
    19441 gtcaccgtcg cccccgtgcg caccgacacg cccaggtcga cacaccgcga aagcagcgcg
    19501 tcggccagcg tccccaaccc gccgggcacg taccaacccc cgaacgacag ttccgcgtac
    19561 ggcaccgccg ccagcgcggc cggcgcccgt cgggggtcgg cgccggtgta ggtcgcgtag
    19621 cggtcgagca gcatccgcag ccggggatcc cgcagccgcc gcaggcccag gccgcgcagc
    19681 gactggcccg gggccaccgc ggccaggtca ccgagccgcc aggccagccc ggccagcgcg
    19741 gccggcgagt cgaccgggcg gcgcaggatg tcacgccacg acgcgtccca gacccgcccg
    19801 gcccgccgcc acaggccctg ccagtccaaa gccgcctcgg caccgagcgc ggcgccgatc
    19861 cgctcagcga actcggccgg atcggcgcac gagtcgagca ccgtgccgtc ggcgaacacg
    19921 tgccggacca ccgggttcag tggcaccagc ggcggggcca caccgccgag gtcggcgaac
    19981 agctcgtcga acacctgcgg cagcgtgagc aggctcggcc cggtgtcgaa tcgaaaaaca
    20041 ccctcgggcc gtgcgaccac ccggcggccg agcttgccgc cgaccaccgt ggaccgctcg
    20101 tacacggtga cgtggtgtcc ggttgccgcg agccgcgccg cgcacgccag cccacccacg
    20161 ccggccccga ccacgacgac ctcagccacg cccgcctccg aggatcacag caccaccggc
    20221 cggtcccgcc accgcagcgc gccggcgcgc cgcagccggt aggaacggac caccaaccag
    20281 ccgaacaaga gcaccgacac cggctgagcc agcgcgtccg gccaccacct cccgcccgtc
    20341 gccgccgcgc tcgccacgcg gccgagcacc cccagggcat aggccacaca cccggccagc
    20401 accaccggca gcgaccacgt caccaacccg aagacagtca acaacacggg tacgacataa
    20461 acgagcagca gcagccccac cacggccgca gcgccaagag cggacccgaa cgacgcccac
    20521 agcgacttcg tgtagccggc gacgagcgag tcccacgacg agtacatccg gcactccgcg
    20581 acccgcgacc cgtcggccag cgcgatccgc ccacccgacc gtttgaccgc ccgggccagc
    20641 gagatgtcct ccagcaccga cgaccgcacc gccgcatgcc caccggccgc caggtaagcc
    20701 gaacgatcca ccaccaggaa ctgcccaccg gccgccgcca gcgacggccg cgccgagcgc
    20761 tccagcgccc gcagcggcag gaacgtcagc cacgaccact gcaacagcgg ctgcacgagc
    20821 cgctcacccc acgaccccac gacgatgcgg gggtacggcg acagcagccc gacgcccgcc
    20881 gagcgcagca gggccgccgc acccgcgacg gccgaaggcg acagcaccac gtccgcgtcg
    20941 acgaacgcca gcacccgggc cgccgggtcg gccgcgtcgg cgagctgctg gcaggcgtgc
    21001 ggcttgccga gccagcccgg cggcagcggc gccccggtga gcagccgcac gcgcgggtcg
    21061 tcgccggcca ccgcacgtac cacgtctgcg gtcccgtcgg tcgacccgtc gtcgaggacc
    21121 aggatggaca agggcacgcc acgctggccc agcaacgacc gcaggcacgg ctccacccgg
    21181 gcggcctcgt cgcgcaccgg caacagcacc gccaccggct cgggaaaggc cgcgtccgag
    21241 gggcggcgca gcagcctggc gttgatcgcg gcgtgcacgg ccagggcgcc ggccaacagg
    21301 gctggcagcc aggcgagcgc gctcacgtcc gtacccgatg caagatcagg gtgacggcga
    21361 gcggcaacgc gaccagcccc atgcccaggg caccccagcc agccgacgcg gacagcccga
    21421 ggaaagcggc gtgggccagg atgctggaga aataggtcca caggtacagc gcgtacatcg
    21481 gcgcgtccgg cccgatgacc agcgcggcgg ggccggccag cccgctgaac acggtcatca
    21541 tcaggatcgc gacgaccagc cagccggcgt agttgcccag cggcacgtcc ggcaccccgg
    21601 gcaggctcgg cgacgggttc gaccaggtcc agtagccctc ggcgaccatc tgcgggtcga
    21661 ggaacaggtc ccacgcggcg aggccgacgc cggccacccc gacccgcagc gcggtgggcc
    21721 ggaccagccg cacggccgcg agccaggccg gccacgccat ccaggtccag gccagcggga
    21781 tcacccacgg cacaccggcg atcttcggac cgagcgcccc ggagtacgcg tattcgccga
    21841 acggcgcgcc gctcgccacc cccgccgcct cgacgaagag cccgcctccc gtggtgacca
    21901 ccaccagcac ggccgcgacc cgtgggccgc gggtcagtgc ggcgtggccg accgacagca
    21961 cgtagccgag gacgaccgtc gtgacggtga ccgcggtgcg ggcgccgtca tcggtcagtg
    22021 gatagcagat ctgggcgagg atcagcagac ccagcccgta ccagggcagc ttgcgggtca
    22081 ttccccggac ggcgcgcgca ccggcaggtc ccggccgagc accgcgaagg cccgctcgtc
    22141 gccgggaaag cggaagtcgc gcagcacgtc gacgaactcg aagctgcggt agagccgcca
    22201 ggcgcgggac ttctgctcgt cggcctccgg tgtggacagc aacgtggtcg cgccgggcgc
    22261 catgccgagc agcgcgcgca gctggcgggc cccgacgccg tgaccctgcg cggccgggcg
    22321 gacgtgcagc tcgacgacct cgaagcagtc ggtcagccag cgcttccggt gctcctcgct
    22381 gagcgcggag cggacctggt cgtgccacca ctgaccggcc ccggagacat agccgtagcc
    22441 gaaaccggcc aggtgtccgt cggtggtcag cgtggcgacc gcgcggaaac cggaacggcg
    22501 cacgtgcgtg gcgatgatcc cgcgccgggc ctccatcagc tccggccggt aacccatcgc
    22561 ctctccgtag acggccacca cgtcgtcgag ccgacgtgcc aggtcgtccg gcttccacgg
    22621 caccagcctc atgccggatc gctccttgtc atctgttgcc agccgagcac cccgcggtca
    22681 cccatgatgc cgcataccgc gaaccgggcg aaaagctcct cggcgtacca gtcgacctgt
    22741 gccgtgcgcg cgatggcggc acgatgctcc ggctgacggt acgcgaagcc gaccagatcc
    22801 gttgtgctcc gccacacggt gaccgtgccc tgccagccga tcggtgcctc gccgacgccg
    22861 aaccgggcga gcagtcccgg cgcgtcgcgc agggatgcgg ccaccggggg gatggcgcgc
    22921 cagaaggtcg cggcccgcga cggcttcagg cgggcccggg tcagggcgag gaccattccg
    22981 tcggtacggg tggtttgtgt tttttggaag ggttggtggc cgctccaggt gccgcggctg
    23041 gcgatgggtt ccaggtcgac tctcgcgtgc gccgtgctga ggtcggtcca gctctcgatg
    23101 gctcgtggcg ttttgtcttt ttcgtgtacg agcagggccg cccagcgggt ggcgtcgacg
    23161 tcgccggggc cgaagccggt gccggtgccc gtgccgagca gcttcgcgaa gcggacgccg
    23221 gggtggcggc ggaggcgggc gcggtcggtc gccatccggg cgagcacgtg cgggatcttc
    23281 cgcgtgggga cccgccagac gtgcagggtg acgaccgtgt ccatcgcgcc cagtctccac
    23341 cgtctcgttt cggggtggtc aggcgacgtc ggtgacggtg cccccggtta gtcgctcgag
    23401 ctcggccggg gtgatcggga agacggcgtg cgcgatgccg ccggcggccc agacctcttc
    23461 gaacgagaac agggcggtgt cgacgagggt acgcatggcg gggcggcccg ggtggacggg
    23521 cgcgacgccg ccgatcacct ggccgctgtg ttcgcggacg aagtcggggt tggcgcggcg
    23581 gaccttctcg atgccgtgct ccttggccac ccgggcggtg tcgacccggt gcgcgccgct
    23641 ggtgagcacc agcagcggcg cgccgtcggc gtcgaagacg agcgagttgg cgatctggcc
    23701 gacttcgacg ccgagctgtt ccgcggccgc cgcggcggtg ggcgcggcgg ccggcagcat
    23761 ccggacctgg ctgggctggc cggcggcgtc gcgggcaccg gcggcgtcga gcgcgtcctg
    23821 gacggcgcgg acgttgggat gcggttgcat cgggacacgt tctcacgccg tgcggcagtt
    23881 cgcttctcgt ttccacgtgg tggcgttcgc gctggtcggc gacgtgttgg gggtcggcgg
    23941 cgggtgccgg ggaacatcag ccgacatgag cgcgcggcgc gttgcttttt tgtcggaccc
    24001 aaggtgtact cttcttgtag ttagaacgcg tgttcgatta gctcgcacac tcgttctggc
    24061 ggtccgggag gcgcgattcg cggcgcggct tccggaacgt gcggcttcgc gggccgcaca
    24121 tcaggcagga ccgtcgcccg ccgccctcga cccccgggcg gtgggcgacg gaccagccga
    24181 cctgccggtc gggtgtggtg tggggaagcg tcacgcccga ccggcaacta gcactaccgc
    24241 tgcgccttcc tccgccgcgg ggcacgtccg cgggtccttc cggggcccgt gcacaggctg
    24301 catacgcgga ggagacaggt tcatgacgac cagcccggcc caggcgccga ccgtgccggc
    24361 acacgtgctg ccacaccgca cgccggccca gctgctcgcg
//
