LOCUS       NZ_FZOF01000072         5516 bp    DNA     linear   CON 02-JAN-2025
DEFINITION  Actinacidiphila glaucinigra strain CGMCC 4.1858, whole genome
            shotgun sequence.
ACCESSION   NZ_FZOF01000072
VERSION     NZ_FZOF01000072.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinacidiphila glaucinigra
  ORGANISM  Actinacidiphila glaucinigra
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Actinacidiphila.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900188405.1-RS_2025_01_02
            Annotation Date                   :: 01/02/2025 02:14:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,793
            CDSs (total)                      :: 8,707
            Genes (coding)                    :: 8,547
            CDSs (with protein)               :: 8,547
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1 (5S, 16S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 47 of 160
            Pseudo Genes (incomplete)         :: 136 of 160
            Pseudo Genes (internal stop)      :: 6 of 160
            Pseudo Genes (multiple problems)  :: 29 of 160
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:25:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 5516
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FZOF01000072.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..5516
                     /db_xref="taxon:235986"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0079895_172"
                     /organism="Actinacidiphila glaucinigra"
                     /strain="CGMCC 4.1858"
                     /type_material="type strain of Streptomyces glauciniger"
     gene            complement(<1..>5516)
                     /locus_tag="CHF15_RS43690"
                     /old_locus_tag="SAMN05216252_1721"
     region          1..5516
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..5516
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..5516
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[<0:5516](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..5516)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     CDS             complement(<1..5516)
                     /NRPS_PKS="Domain: PKS_DH (20-186). E-value: 1.8e-66.
                     Score: 215.6. Matches aSDomain:
                     nrpspksdomains_CHF15_RS43690_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (513-820). E-value: 2.8e-120.
                     Score: 393.1. Matches aSDomain:
                     nrpspksdomains_CHF15_RS43690_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (829-1008). E-value: 9.9e-59.
                     Score: 190.3. Matches aSDomain:
                     nrpspksdomains_CHF15_RS43690_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1103-1189). E-value: 1.1e-30.
                     Score: 97.8. Matches aSDomain:
                     nrpspksdomains_CHF15_RS43690_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1219-1641). E-value:
                     2.9e-179. Score: 588.4. Matches aSDomain:
                     nrpspksdomains_CHF15_RS43690_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060784.1"
                     /locus_tag="CHF15_RS43690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_1721"
                     /product="type I polyketide synthase"
                     /protein_id="WP_143681803.1"
                     /sec_met_domain="ADH_N (E-value: 1.1e-09, bitscore: 24.4,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.2e-21, bitscore:
                     62.5, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.6e-64, bitscore:
                     203.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.7e-13, bitscore:
                     37.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 3.2e-225, bitscore:
                     733.8, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 5.6e-90, bitscore:
                     287.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3e-37, bitscore: 114.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIESGRGAGDLRAVGLEALGHPLLGATVALADSDGFLFTGRLSLD
                     THPWLADHAVMGTVLLPGAAFVELAVRAGDQVGCDVLEELTLQAPLVLPERGGVQVQIH
                     VAAPDADGTGRRTFTLSSRAEDSAADVSWVRHADGVLAQGAGKPDFELTQWPPAGAEAA
                     DTDDLYEVLAGLGMGYGPVFRGLTAAWRRGESVYVEVALPEGHTAAARDFGLHPALLDA
                     ALHALALGGLGGTVGVGRLPFSWTGVTLHAAGAEALRVHVARTGADGVRLEIADTTGAP
                     VATVDALALRTVSAEQVRLAEAAHLESLFGVEWAPVTVAPGDGAEDRRWAVLGRDELGM
                     ASAGAVVVEYADLAALGEALSTGEPLYDAVVVHLPGTGHDGVAGAVHSAVRGALGTVQE
                     WLADERFADTRLVWLTSGAVTTVPGGAVADLSGAAVRGLLRSAQSENPGSFVMIDLDDD
                     PASAGVLAAALATGEPQLAIRRGMVQAPRLARVPATPALTPPADSVAWRMDIEHRGTVD
                     NLVLVPSPEAEAPLEAGQVRVAVRAAGLNFRDVLSALGMYPGDAGLMGSEGAGLVVETG
                     PGVTDLAPGDRVMGMLPGAFGPLAVVDRRMVVPMPDGWTFAEAASVPIVFMTAYYALHD
                     LAALRGGESVLVHAAAGGVGMAAVQLARHWGVDVYATASPGKWETLRGLGLADDRIASS
                     RTLDFEDAFRSATGGRGVDVVLDSLAREFVDASLRLLPRGGRFVEMGKTDVRSPEDVAA
                     AHPGVTYQAFDLIEAGLDRIQAMLTELLALFRSGALHLLPVSAWDLRQAPEAFRHLSQA
                     RHVGKIVLTLPTDWDPEGTVLITGGTGALGGLVARHAVTTRGARHLLLTSRRGESAAGA
                     RELAAELGAMGAEVTIAACDTADRDALAALLESVPAEHPLTAVVHTAGVLDDGVIDSLT
                     PERLERVLRPKVDAALHLHDLTRHLDLADFVLFSGIAAAFGAAGQANYAAANAFLEGLA
                     EQRRAQGLVATALAWGLWAPQVGGMATRLDEADLQRMARDGVGALSGREGLALFDTALA
                     VGAAVLLPMRLDIGALRAQAQTGSLPSLLRGLVGAPTRRAVAATGAGGEAGFRERLAGL
                     APAERDRVLLDLVRKQVAIALGYPGAGSVEPGRSFKELGFDSLTAVELRNLLGAATGKR
                     LPATLVFDYPTATALAGYLREELVGDLTDADAARVGTALAPSGPRTVEADDDPIAIVAM
                     SCRYPGGVRSPEDLWRLVEAGGDAISGLPADRGWDTGELLVHGDARTFQGGFLYDADLF
                     DADFFGISPREALAMDPQQRLLLETAWETFERAGIDPATMRGSRAGVFVGAAYTGYDAQ
                     LEQSGTDEVLGHVMTGNAGSVMSGRVSYALGLEGPAVTVDTACSSSLVALHWAVQALRQ
                     GECSMALAGGVTVMSTPTTFSEFGLQGGLSPDGRCKAFAGAADGTGWAEGVGMLLVERL
                     SDARRNGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSSADVDAVEA
                     HGTGTRLGDPIEAQALLATYGQERSPEQPLLLGSVKSNLGHTQAAAGVAGIIKMVMAMR
                     HGVLPRTLHVDEPTPHVDWSAGDIALLTEAVEWPDTRRPRRAGVSSFGISGTNAHTIIE
                     QAPGGITEADESPSQAPGVLPYVLSARTPDALRAQARKLLSVVESGGGPRPADLAHSLA
                     TSRAALDDRAAIVSDGIDGLRTALVALAEGEQTPGLLRGAAAAGSLAFLFTGQGSQRLT
                     MGRELYDAYPVFAEALDAISAHLDVPLPEVLFGDDAALLDRTEFAQPALFAVEVALFRL
                     LESWGVRPDFVSGHSLGEIAAAHV"
     CDS_motif       complement(69..134)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0013"
                     /evalue="8.00E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="1816"
                     /protein_start="1794"
                     /score="15.7"
                     /tool="antismash"
                     /translation="LDRTEFAQPALFAVEVALFRLL"
     CDS_motif       complement(231..278)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0012"
                     /evalue="2.60E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="1762"
                     /protein_start="1746"
                     /score="16.8"
                     /tool="antismash"
                     /translation="FTGQGSQRLTMGRELY"
     aSDomain        complement(594..1859)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CHF15_RS43690_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.90E-179"
                     /label="CHF15_RS43690_PKS_KS.1"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="1641"
                     /protein_start="1219"
                     /score="588.4"
                     /tool="antismash"
                     /translation="IAIVAMSCRYPGGVRSPEDLWRLVEAGGDAISGLPADRGWDTGEL
                     LVHGDARTFQGGFLYDADLFDADFFGISPREALAMDPQQRLLLETAWETFERAGIDPAT
                     MRGSRAGVFVGAAYTGYDAQLEQSGTDEVLGHVMTGNAGSVMSGRVSYALGLEGPAVTV
                     DTACSSSLVALHWAVQALRQGECSMALAGGVTVMSTPTTFSEFGLQGGLSPDGRCKAFA
                     GAADGTGWAEGVGMLLVERLSDARRNGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRV
                     IRQALASAGLSSADVDAVEAHGTGTRLGDPIEAQALLATYGQERSPEQPLLLGSVKSNL
                     GHTQAAAGVAGIIKMVMAMRHGVLPRTLHVDEPTPHVDWSAGDIALLTEAVEWPDTRRP
                     RRAGVSSFGISGTNAHTIIEQAP"
     CDS_motif       complement(816..860)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0011"
                     /evalue="1.60E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="1567"
                     /protein_start="1552"
                     /score="11.0"
                     /tool="antismash"
                     /translation="GSVKSNLGHTQAAAG"
     CDS_motif       complement(921..965)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0010"
                     /evalue="4.20E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="1532"
                     /protein_start="1517"
                     /score="12.5"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       complement(1341..1388)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0009"
                     /evalue="9.10E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="1392"
                     /protein_start="1376"
                     /score="20.7"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     aSDomain        complement(1950..2207)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CHF15_RS43690_PKS_PP.1"
                     /evalue="1.10E-30"
                     /label="CHF15_RS43690_PKS_PP.1"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="1189"
                     /protein_start="1103"
                     /score="97.8"
                     /tool="antismash"
                     /translation="LAGLAPAERDRVLLDLVRKQVAIALGYPGAGSVEPGRSFKELGFD
                     SLTAVELRNLLGAATGKRLPATLVFDYPTATALAGYLREEL"
     aSModule        complement(1950..5456)
                     /domains="nrpspksdomains_CHF15_RS43690_PKS_DH.1"
                     /domains="nrpspksdomains_CHF15_RS43690_PKS_ER.1"
                     /domains="nrpspksdomains_CHF15_RS43690_PKS_KR.1"
                     /domains="nrpspksdomains_CHF15_RS43690_PKS_PP.1"
                     /incomplete
                     /locus_tags="CHF15_RS43690"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(2493..3029)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CHF15_RS43690_PKS_KR.1"
                     /evalue="9.90E-59"
                     /label="CHF15_RS43690_PKS_KR.1"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="1008"
                     /protein_start="829"
                     /score="190.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLITGGTGALGGLVARHAVTTRGARHLLLTSRRGESAAGAREL
                     AAELGAMGAEVTIAACDTADRDALAALLESVPAEHPLTAVVHTAGVLDDGVIDSLTPER
                     LERVLRPKVDAALHLHDLTRHLDLADFVLFSGIAAAFGAAGQANYAAANAFLEGLAEQR
                     RAQGLVATALAWGLWA"
     CDS_motif       complement(2538..2639)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0008"
                     /evalue="1.40E-16"
                     /label="PKSI-KR_m4"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="993"
                     /protein_start="959"
                     /score="53.0"
                     /tool="antismash"
                     /translation="FVLFSGIAAAFGAAGQANYAAANAFLEGLAEQRR"
     CDS_motif       complement(2925..3026)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0007"
                     /evalue="2.30E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="864"
                     /protein_start="830"
                     /score="26.6"
                     /tool="antismash"
                     /translation="TVLITGGTGALGGLVARHAVTTRGARHLLLTSRR"
     CDS_motif       complement(3057..3104)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0006"
                     /evalue="1.20E-05"
                     /label="PKSI-ER_m9"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="820"
                     /protein_start="804"
                     /score="18.2"
                     /tool="antismash"
                     /translation="AFRHLSQARHVGKIVL"
     aSDomain        complement(3057..3977)
                     /ASF="ER domain putatively catalyzing 2S-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CHF15_RS43690_PKS_ER.1"
                     /evalue="2.80E-120"
                     /label="CHF15_RS43690_PKS_ER.1"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="820"
                     /protein_start="513"
                     /score="393.1"
                     /tool="antismash"
                     /translation="GTVDNLVLVPSPEAEAPLEAGQVRVAVRAAGLNFRDVLSALGMYP
                     GDAGLMGSEGAGLVVETGPGVTDLAPGDRVMGMLPGAFGPLAVVDRRMVVPMPDGWTFA
                     EAASVPIVFMTAYYALHDLAALRGGESVLVHAAAGGVGMAAVQLARHWGVDVYATASPG
                     KWETLRGLGLADDRIASSRTLDFEDAFRSATGGRGVDVVLDSLAREFVDASLRLLPRGG
                     RFVEMGKTDVRSPEDVAAAHPGVTYQAFDLIEAGLDRIQAMLTELLALFRSGALHLLPV
                     SAWDLRQAPEAFRHLSQARHVGKIVL"
     CDS_motif       complement(3360..3398)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0005"
                     /evalue="2.10E-04"
                     /label="PKSI-ER_m7"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="719"
                     /protein_start="706"
                     /score="13.9"
                     /tool="antismash"
                     /translation="TGGRGVDVVLDSL"
     CDS_motif       complement(3531..3593)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0004"
                     /evalue="1.40E-09"
                     /label="PKSI-ER_m5"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="662"
                     /protein_start="641"
                     /score="30.2"
                     /tool="antismash"
                     /translation="GESVLVHAAAGGVGMAAVQLA"
     CDS_motif       complement(3618..3662)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0003"
                     /evalue="2.30E-05"
                     /label="PKSI-ER_m4"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="633"
                     /protein_start="618"
                     /score="17.6"
                     /tool="antismash"
                     /translation="AASVPIVFMTAYYAL"
     CDS_motif       complement(3852..3887)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0002"
                     /evalue="8.70E-04"
                     /label="PKSI-ER_m1"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="555"
                     /protein_start="543"
                     /score="12.3"
                     /tool="antismash"
                     /translation="GLNFRDVLSALG"
     aSDomain        complement(4959..5456)
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CHF15_RS43690_PKS_DH.1"
                     /evalue="1.80E-66"
                     /label="CHF15_RS43690_PKS_DH.1"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="186"
                     /protein_start="20"
                     /score="215.6"
                     /tool="antismash"
                     /translation="HPLLGATVALADSDGFLFTGRLSLDTHPWLADHAVMGTVLLPGAA
                     FVELAVRAGDQVGCDVLEELTLQAPLVLPERGGVQVQIHVAAPDADGTGRRTFTLSSRA
                     EDSAADVSWVRHADGVLAQGAGKPDFELTQWPPAGAEAADTDDLYEVLAGLGMGYGPVF
                     RGL"
     CDS_motif       complement(5298..5372)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CHF15_RS43690_0001"
                     /evalue="1.00E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="CHF15_RS43690"
                     /protein_end="73"
                     /protein_start="48"
                     /score="30.9"
                     /tool="antismash"
                     /translation="WLADHAVMGTVLLPGAAFVELAVRA"
ORIGIN
        1 acatgagcgg cggcgatctc accgagcgaa tgaccggaca cgaagtccgg cctcacgccc
       61 caggactcca gcagccggaa cagcgccacc tccacagcga acaacgccgg ctgcgcgaac
      121 tccgtccggt cgaggagagc cgcgtcgtcg ccgaacagca cttccggcaa cggcacatcg
      181 aggtgcgcgc tgatcgcgtc cagcgcctcc gcgaacacgg ggtacgcgtc gtacagctca
      241 cggcccatcg tcagtcgctg gctgccctgc cccgtgaaca ggaacgcgag cgagccggcg
      301 gcggccgccc cccggaggag gccgggggtc tgctctcctt cggcgagagc cacaagggcg
      361 gtcctcagac cgtcgatgcc gtcggagacg atcgcggccc ggtcgtccag ggccgcccgg
      421 ctggtcgcca gcgagtgggc caggtcggcg ggacgcgggc caccgccgga ctcgaccacc
      481 gacagcagct ttcgggcctg ggcgcgcagg gcgtcggggg tcctggccga caggacgtac
      541 ggaagcacgc cgggcgcctg cgacggagac tcgtcggcct cggtgatccc gcccggtgcc
      601 tgctcgatga tcgtgtgggc gttggtgccg ctgatgccga acgacgagac gccggcacga
      661 cgcgggcgcc gggtgtcggg ccactcgacg gcctcggtca gcagggcgat gtctcccgcc
      721 gaccagtcga cgtgcggggt gggctcgtcc acgtgcaggg ttcggggcag cacgccgtgc
      781 cgcatcgcca tgaccatctt gatgatgccc gcgacaccag cggcggcctg cgtgtgcccg
      841 aggttggact tgacggagcc gagcagcagc ggctgctcgg gcgaacgctc ctgcccgtag
      901 gtggccagca gcgcctgcgc ctcgatcggg tcacccagcc gcgtaccggt gccgtgcgcc
      961 tcgaccgcgt ccacgtcagc gctcgacagg cccgcactcg ccagagcctg ccggatcaca
     1021 cgctgctgcg aagggccgtt cggcgccgtc agaccattgc tcgcgccgtc ctggttcacc
     1081 gccgaacccc gcaccagagc gaggaccggg tgaccgttcc gccgggcgtc cgacagccgc
     1141 tccacgagca gcatgcccac accctccgcc caccccgtgc cgtcggcggc gccagcgaac
     1201 gccttgcagc ggccgtcggg cgacagaccg ccctggaggc cgaactcgct gaaggtggtg
     1261 ggggtggaca tgaccgtcac accgcccgcc agggccatgg agcactcgcc ctgccgcagt
     1321 gcctgcaccg cccagtgcag cgcgaccagg gacgaggaac aggccgtgtc caccgtcacc
     1381 gccgggccct cgagccccag cgcgtacgag acacggcccg acatcacact gcccgcgttg
     1441 cccgtcatca cgtggccgag gacctcgtcg gtgccggact gctcaagctg cgcgtcgtac
     1501 ccggtgtagg cggctccgac gaagacaccc gcccggctgc cgcgcatggt ggccgggtcg
     1561 atgcccgcgc gctcgaaggt ctcccaggcg gtttcgagca ggagccgctg ctgcggatcc
     1621 atggccagcg cctcacgcgg ggagatcccg aagaagtccg cgtcgaaaag gtcggcgtcg
     1681 tacaggaagc cgccctggaa ggtccgcgca tcgccgtgga cgaggagttc gccggtgtcc
     1741 cagccgcggt cggcggggag gcccgagatc gcgtcgccgc cggcctcgac cagacgccac
     1801 aggtcctccg ggctgcggac gccgccgggg tagcggcagc tcatcgcgac gatcgcgatg
     1861 ggatcgtcgt ccgcctcgac cgttcgcggt ccgctcggcg cgagggcggt ccccacccgg
     1921 gccgcgtcgg cgtccgtaag gtcgccgaca agctcttcac gcaggtatcc ggcgagcgcg
     1981 gtggccgtcg ggtagtcgaa gacgagcgtg gcgggcagac gcttgcccgt tgcggcaccg
     2041 agcaggttgc gcagctcgac agcggtcagg gagtcgaagc ccagctcctt gaacgagcgc
     2101 ccgggctcga cggagcccgc cccggggtag cccagcgcga tggcgacctg cttgcggacc
     2161 agatccagca gaacacggtc acgctcggcc ggagccagcc cggccagacg ctcccggaaa
     2221 ccggcctccc ctcccgcgcc cgtggcggcc acggcacggc gagtgggagc cccgaccaga
     2281 ccacgcagca gcgatggcag ggaaccggtc tgggcctggg cgcgcaacgc cccgatgtcg
     2341 agcctcatcg gcagcagcac cgcggcaccg acggccagcg ccgtgtcgaa cagagcaagg
     2401 ccttcccggc ccgagagggc gcccacgccg tcccgggcca tgcgctggag atcggcctcg
     2461 tccagccgtg tcgccatacc gcccacctgc ggggcccaca ggccccacgc gagcgcggtg
     2521 gccacgagcc cctgggctcg ccgctgctcg gcaaggcctt ccaagaaggc gttggcagcg
     2581 gcgtagttcg cctgcccggc cgcgccgaaa gccgcggcga tccccgagaa caggacgaag
     2641 tcggcgaggt cgaggtggcg ggtgaggtcg tgcaggtgga gggccgcgtc gaccttgggg
     2701 cgaagaaccc tctcgagccg ctcgggggtg agggagtcga tgacaccgtc gtcgaggacg
     2761 cccgccgtgt gcacgacagc cgttagcggg tgctcggccg gtacggactc cagcagggcg
     2821 gccagcgcgt cgcggtcggc ggtgtcgcag gcggcgatcg tcacctcggc gcccatggcg
     2881 cctagttcgg cggccagttc acgggctccg gcggcggact caccacggcg gctggtcagc
     2941 agcaggtgac gggcgccgcg cgtggtgacg gcgtgccggg cgaccaggcc gccgagcgca
     3001 cccgtgccac cggtgatgag gacggtgccc tcggggtccc agtcggtcgg cagggtcagc
     3061 acgatcttgc cgacgtgacg tgcctggctc agatgacgga acgcctcggg cgcctgacgc
     3121 aggtcccacg cggagaccgg gagcaagtgc agggcaccgg atcggaacag cgccagcagt
     3181 tcggtgagca tcgcctgaat gcggtcgagt ccggcctcga tcaggtcgaa cgcctggtag
     3241 gtgactccgg ggtgagcggc ggcgacgtcc tccggcgagc ggacgtcggt cttgcccatc
     3301 tccacgaagc gcccgccacg cggcagcaac cgcaacgaag catccacgaa ctcccgcgcg
     3361 agggagtcga ggacgacatc gacgccgcgt ccgcccgtgg cgctgcggaa cgcgtcctcg
     3421 aagtcgagcg tgcgggacga ggcgatgcgg tcgtcggcca ggccgagccc gcgcagcgtc
     3481 tcccacttgc cgggactcgc cgtggcatac acatccacgc cccagtgacg ggccagctgc
     3541 acggcggcca tacccacgcc acccgcggca gcgtggacga gcaccgactc cccaccgcgc
     3601 agtgcggcaa ggtcgtgcag cgcgtagtac gccgtcatga acacgatcgg caccgacgcc
     3661 gcctcggcga acgtccaacc gtccggcatc gggacgacca tgcggcgatc gaccaccgcg
     3721 agcgggccga acgccccggg cagcatcccc atgacgcggt cgccgggggc gaggtcggtg
     3781 acaccggggc cggtctccac gacgaggccg gcgccctcgc ttcccatcag ccccgcgtca
     3841 cccgggtaca tgcccaacgc gctcaggacg tcacggaagt tcagccccgc cgcccgcacc
     3901 gcgacgcgga cctggcccgc ctccagcggc gcctccgcct cggggctggg gacgaggacg
     3961 aggttgtcga cggtgcccct gtgctcgatg tccatgcgcc aggcgacgct gtccgcgggc
     4021 ggggtcagcg ctggcgtggc cgggacccgg gccagccggg gcgcctgcac catgcctcgg
     4081 cggatggcga gctgcggctc accggtggcg agggccgcgg cgaggacccc agccgaggcc
     4141 gggtcgtcgt cgaggtcgat catcacgaag ctgccgggat tctccgactg cgccgagcgc
     4201 agcagtcccc gtaccgcggc gccggaaaga tccgcgaccg ctccacccgg caccgtcgtc
     4261 acggcgcccg acgtcagcca caccagccgc gtgtccgcga agcgctcgtc cgcgagccac
     4321 tcctgaacgg ttcccagcgc accccgcacc gctgaatgca ccgcgccggc cacgccgtcg
     4381 tgaccggtgc cgggcaggtg gacgacgacc gcgtcgtaga gcggctcgcc tgtcgaaagc
     4441 gcctcgccga gcgcggcgag gtcggcgtac tccaccacga cagcgcccgc agaggccatg
     4501 cccagttcgt cccgcccgag gacggcccag cgccgatcct ccgcaccgtc accgggcgca
     4561 acggtcacag gcgcccattc cacgccgaac aacgactcca ggtgcgcggc ttcggccagg
     4621 cgtacctgct cggcggagac cgtgcgcagt gcgagggcgt ccacggtggc gacgggtgcg
     4681 ccggtggtgt cggcgatctc caggcgcacg ccgtccgcgc ccgttcgcgc gacgtggacc
     4741 cgcagggcct cggcgcccgc cgcgtgcagc gtcaccccgg tccaggagaa cggcagccgc
     4801 cccacgccca cggtgccgcc gagcccaccc agcgccagcg cgtgcagggc cgcgtcgagc
     4861 agggcagggt gcaggccgaa gtcccgcgcg gcagcggtgt gcccctcggg cagcgcgacc
     4921 tcgacgtaga cgctctcccc gcgccgccac gcggccgtga gcccgcggaa caccggcccg
     4981 tagcccattc cgagcccggc cagcacctcg tacagatcgt ccgtgtccgc ggcctcggct
     5041 cccgccgggg gccactgagt gagctcgaag tccggctttc cggcgccctg ggcgaggacg
     5101 ccgtcggcgt gccgcaccca cgacacatcg gcggcgctgt cctcggcgcg ggaggagagc
     5161 gtgaacgtgc gacgacctgt gccgtccgcg tcgggcgcgg ccacgtggat ctgcacctgc
     5221 acgccgccgc gctcggggag aacgagcggg gcctggaggg tgagttcctc cagcacgtca
     5281 caaccgacct ggtcaccggc acgaacggcc aactccacaa aggccgcgcc gggaagcagg
     5341 acggtgccca tgacggcgtg gtcggcgagc caggggtgcg tgtcgaggga gagacggccc
     5401 gtgaagagga agccgtcgga gtcggcgagc gccacggtcg cgcccagcag cgggtgaccc
     5461 agggcctcca ggccgacagc gcgcagatcg ccggcgccgc ggcccgactc gatcca
//
