LOCUS       NZ_FZOF01000050        19762 bp    DNA     linear   CON 02-JAN-2025
DEFINITION  Actinacidiphila glaucinigra strain CGMCC 4.1858, whole genome
            shotgun sequence.
ACCESSION   NZ_FZOF01000050
VERSION     NZ_FZOF01000050.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinacidiphila glaucinigra
  ORGANISM  Actinacidiphila glaucinigra
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Actinacidiphila.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900188405.1-RS_2025_01_02
            Annotation Date                   :: 01/02/2025 02:14:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,793
            CDSs (total)                      :: 8,707
            Genes (coding)                    :: 8,547
            CDSs (with protein)               :: 8,547
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1 (5S, 16S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 47 of 160
            Pseudo Genes (incomplete)         :: 136 of 160
            Pseudo Genes (internal stop)      :: 6 of 160
            Pseudo Genes (multiple problems)  :: 29 of 160
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:25:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 19762
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FZOF01000050.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..19762
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="redox-cofactor"
                     /region_number="1"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     gene            <1..1045
                     /locus_tag="CHF15_RS42090"
                     /old_locus_tag="SAMN05216252_1501"
     cand_cluster    1..19762
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..19762
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7608:9762](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(7609..9762)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     CDS             <3..1045
                     /codon_start=2
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009719178.1"
                     /locus_tag="CHF15_RS42090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_1501"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_107418622.1"
                     /transl_table=11
                     /translation="KLRDDSKATGSGPYKLDSYEAGKEAVFSVNGDYQGSAEIRNSGMT
                     MKFFGDEPALKKAVEDGSVDLAYRGLDSADIASLQSSSIAGDTGIQVVEGTGAEVQHLV
                     FNVEDPVVGNKAVRRAVAYLIDRKAFIRDVYQRTASPLYSIVPAGITGHNTAFFDRYGE
                     GGDKAGAQAALSQAGITDKVSFTLWATPVRFGPGTVAELKAIAKQLNDSGLFDVDVKTT
                     DADQYAKDIEAGKYAVYVRGWVPDYPDPDNFTAPFFGDGNVLGNNYVNKKITDELLPRT
                     AAEAGRAATSTDFEDLQNAVADDVPIIPLWQGKQYVVSRDNINGLEWTLDPSTVFRFWE
                     IQKGVTE"
     gene            complement(1235..>1483)
                     /locus_tag="CHF15_RS42095"
                     /old_locus_tag="SAMN05216252_1502"
                     /pseudo=""
     CDS             complement(1235..>1483)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103134.1"
                     /locus_tag="CHF15_RS42095"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_1502"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LVGLALPMRDLTGGAGRSFESGIAGTTAVPGVWVAGNATDPTAQV
                     GASAAAGALAGAHINADLATADTETALTAARHDSALT"
     gene            1527..>2516
                     /locus_tag="CHF15_RS42100"
                     /pseudo=""
     CDS             1527..>2516
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005319623.1"
                     /locus_tag="CHF15_RS42100"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPQLSGHRLALSGSLGAGRPRPGQRDGHEPPRPQAAHHGAPHVHV
                     HGQENGHEHDHDTAGQAELLDLDAEVLAEHTASITAWLPFEDRPRRIVDLGCGTGAGTL
                     ALLRRFPAAQVTAVDSSAPHLHRLRANAAAAGMADRVRLVRADLDAPAWPDLGAPELVW
                     ASASLHHMGDPDKTLREVHDFLAPGGLLAVVEPVGFPRFLPEDAPADAPGLEERCHAAL
                     GHHHAEYVPHRGADWAGKLTGAGFAVEAERTLAVDIAPPPTETVTRYALATLRRMRDAV
                     AVAVAVATALTPDDLTALDRLLDAESPDGIPRRTDLRVRTERAVWAARR"
     misc_feature    2718..2733
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: medium, score: 24.96"
                     /tool="antismash"
     gene            <3111..3797
                     /locus_tag="CHF15_RS42105"
                     /pseudo=""
     CDS             <3111..3797
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF018884.5"
                     /locus_tag="CHF15_RS42105"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RLIIGDVCGKGLPTFEDVAAVLGAFREWAPRAATLAELSARLEES
                     FLFHLAESDDLSRDKEERFVTALLLEVRDGERFARMVNHGHPPPIRARRGSVALVAGCP
                     APPLGLYGLRECGAIEERFELCPGDTLLLYTDGLMEARDAAGRCYPLLERATAWRWVRQ
                     GAPSQVCLPDVLGEILEDVVDHAGALPTDDLAMVALTRVEEPGAPVLTWPAGEAWREDA
                     GQWRQD"
     misc_feature    4179..4192
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.91"
                     /tool="antismash"
     misc_feature    complement(4179..4193)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.57"
                     /tool="antismash"
     misc_feature    complement(4180..4193)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.39"
                     /tool="antismash"
     gene            4335..6794
                     /locus_tag="CHF15_RS42110"
                     /old_locus_tag="SAMN05216252_1504"
     CDS             4335..6794
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038032.1"
                     /locus_tag="CHF15_RS42110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_1504"
                     /product="CehA/McbA family metallohydrolase"
                     /protein_id="WP_089229239.1"
                     /transl_table=11
                     /translation="MAGSAVVAVSVGASTAQAATGPASEQGGKVKAAGRTSALNRAKAP
                     TGKWLAGDTHVHDDHSSDGSGPRQTSHQTLPGNLPVGDQIAQGEKAGLDFMPLTDHRTY
                     DQVWDPQWKSSELLLLPGEEANGSPHAIVLGNVDVIVDGANPPGSAAFRHVQQSVWDAH
                     AQGAVWSQAHPDDGEYTPATGPNANASVQGADLAEVLNVSTGPDEQVEYAENRWNAGFR
                     FGVAAASDCHFRELWDVDAPGTPTTHVFAAKRSVLGILDGFRGGRTTVAQNTAGPFLTI
                     EADADGDGVFEAIGGDEVVVADRKLPKKATLRVKVKGGKGTTVHVYAAPGRSAGPIASY
                     RPQRANETYDLPLVLKGTDHGWFRVEARSPGSPSGSDADPNLPDQLRGATSPIFVSVGA
                     PAVPRPEIPLPAADTAGDKAELVTGDLGTFTGFSDVAVVGDVTHIVAEVHEDHASKVVY
                     RRLDGKGRITKSVTLSGRSATARFPRIAAAAKDVWVVWQDEQGKEQPHRPVILLAHSAN
                     GGSSFKAPDKISKGKGRAVHPALALVGDGHPLVAWSDNSGGAFDVYAQIVGVDKAAVNI
                     SAAGKVTSPGVPGDARSPRYPASLFPAVAVHDGRHAVISWQDDRYDPDPLWTGHTPPAG
                     QPAGGGTDPDNWQVLASVRKAPGRAWGNPVQVSKVGDRSDRHPGLTVDEDGTFVAIWES
                     GALQSSGANLQLRAGRSTDGGLTWTAFENVGLDADAMSQRAKLGVDPDGTVRAVWYDSR
                     STDWRWKIFTATLDGAKGWSEATQVSHRGNNTWPALHRGVVVFTSDRGATRTQRDETQQ
                     IFRTKLV"
     gene            7073..7612
                     /locus_tag="CHF15_RS42115"
                     /old_locus_tag="SAMN05216252_1505"
     CDS             7073..7612
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671043.1"
                     /locus_tag="CHF15_RS42115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_1505"
                     /product="manganese efflux pump MntP family protein"
                     /protein_id="WP_089229240.1"
                     /transl_table=11
                     /translation="MIWEILVLGFVLSLDNFRVSIALGTVPFGLKRAVQVALTFGLWDA
                     VMPLVGLLIGRRLGESVGDVADLVGAAALGGYGLYLVVSALRNPEPDELDHPWALFGIP
                     LTLSLDNLLAGASLGLLGLSPWFSAAVFGIMTAVMSLVGLQLGRVTARLIRIRSDLLSG
                     VTLIIAAVALPLWFGA"
     gene            complement(7609..8724)
                     /gene="pqqE"
                     /locus_tag="CHF15_RS42120"
                     /old_locus_tag="SAMN05216252_1506"
     CDS             complement(7609..8724)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019524877.1"
                     /locus_tag="CHF15_RS42120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_1506"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_089229241.1"
                     /sec_met_domain="PTHR43273 (E-value: 3.5e-32, bitscore:
                     102.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.9e-26, bitscore: 83.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.4e-11, bitscore: 35.1,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.8e-11, bitscore:
                     33.0, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSPFGLLAELTYRCPLACPYCSNPLNMAGYRDELALDEWRRVLA
                     EAGDLGVLQCHLSGGEPLLRRDLVEIAAAAHDLGLYTNLVTSAVGLSRPRAERLRAAGL
                     DHVQISIQADEAAVSDRIAGIPSFRRKIEAMRLVKELGWPLTMNVVLHRHNIDRVADVL
                     TLAEEVGADRLELANTQYYGWAWRNRAALLPSRAQLDAAEVVVRAARERLRDRMDVIYV
                     ISDYYSRYPKPCMGGWASRQLTVTPNGDVLPCPAAQSLPLPRASVREDSLARIWAESPV
                     MNAFRGTDWMPEPCRSCFRREVDFGGCRCQAFLLTGDAARTDPVCHLSPDHHLVAGAVE
                     AANTGSRAGDPALVPRPHRARRPDRIPRGSG"
     gene            complement(8717..9046)
                     /gene="pqqD"
                     /locus_tag="CHF15_RS42125"
                     /old_locus_tag="SAMN05216252_1507"
     CDS             complement(8717..9046)
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671045.1"
                     /locus_tag="CHF15_RS42125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_1507"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_089229262.1"
                     /sec_met_domain="PqqD_RRE (E-value: 2.5e-22, bitscore:
                     69.6, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.9e-15, bitscore: 47.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDATSTGTTRAGTRTGPGVEVCGSDRPLLARHVRLTFCRTRQRRI
                     LLHPETVVVLNGSGAAILELCDGRHTVAEIVTELGTRYRAVPGDEVRRFLTRLVARRWM
                     ELTDG"
     aSDomain        complement(8729..8980)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CHF15_RS42125_PqqD_RRE.1"
                     /evalue="2.20E-22"
                     /identifier="RREFam006.1"
                     /label="CHF15_RS42125"
                     /locus_tag="CHF15_RS42125"
                     /protein_end="106"
                     /protein_start="22"
                     /score="69.6"
                     /tool="antismash"
                     /translation="GSDRPLLARHVRLTFCRTRQRRILLHPETVVVLNGSGAAILELCD
                     GRHTVAEIVTELGTRYRAVPGDEVRRFLTRLVARRWMEL"
     misc_feature    9031..9045
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.49"
                     /tool="antismash"
     gene            complement(9052..9762)
                     /gene="pqqC"
                     /locus_tag="CHF15_RS42130"
                     /old_locus_tag="SAMN05216252_1508"
     CDS             complement(9052..9762)
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559516.1"
                     /locus_tag="CHF15_RS42130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_1508"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_179280236.1"
                     /sec_met_domain="TIGR02111 (E-value: 2.4e-98, bitscore:
                     319.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTPARTIRSSGTDGFVETLRAHSRRYHDQHPFHVVMNAGGLSP
                     RQIRGWVANRFYYQENIPRKDAAILSNCPDLEFRRRWLRRITDHDGTAAGEGGIEAWLR
                     LGEAAGLTREEVRDHRHLVPGVRFAVDAYVNFARTRPWVEAVASSLTELFAPDLMAARL
                     AAFERWYPWIDPEGLAYFRTRLEQAPRDCEHALQVVTSHCVSAESQARAVDALSFKCDV
                     LWSLMDSIEQAYPK"
     gene            complement(9767..10654)
                     /gene="pqqB"
                     /locus_tag="CHF15_RS42135"
                     /old_locus_tag="SAMN05216252_1509"
     CDS             complement(9767..10654)
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559515.1"
                     /locus_tag="CHF15_RS42135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_1509"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_089229242.1"
                     /transl_table=11
                     /translation="MLLRVLGSAAGGGSPQWNCGCAVCAAVRSGAAPPRTQSSIAVSAD
                     HRRWFLLNASPDLRAQFEAFPGLHPRGDRTTPLEAVLLTDAELDHTLGLLLLREARALR
                     VYATPATHKTLCDGSGILTTLRRYCTVEWRAVVPGTDLTLANGLSCRAFDVPTAKRARF
                     GGEADHGRVVGYRLTDEHTGGTLVYLPAAQSLTAALRTEIEGCGCLLFDGTCWRDDELV
                     RLGLAGKTAREMGHLPIDGPDGSLSRLPSLAAGRTILVHINNTNPVLLEDAPERRALRE
                     SGIEVATDGLEVQV"
     gene            complement(10778..10900)
                     /gene="pqqA"
                     /locus_tag="CHF15_RS42140"
                     /old_locus_tag="SAMN05216252_15010"
     CDS             complement(10778..10900)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: protein motif:HMM:TIGR02107.1"
                     /locus_tag="CHF15_RS42140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_15010"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_089229243.1"
                     /transl_table=11
                     /translation="MESQPMESQLESQLAVWETPEFEEIAVAAEVTAYVARLED"
     gene            complement(10947..12647)
                     /locus_tag="CHF15_RS42145"
                     /old_locus_tag="SAMN05216252_15011"
     CDS             complement(10947..12647)
                     /EC_number="1.1.2.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559513.1"
                     /locus_tag="CHF15_RS42145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_15011"
                     /product="PQQ-dependent dehydrogenase, methanol/ethanol
                     family"
                     /protein_id="WP_089229244.1"
                     /transl_table=11
                     /translation="MSVDYVDAGEAVDQGLLSGKVAGGEVAPPVVAGLDYERILNARRE
                     PHNWLTYYGAYNGQRYSPLDQINTDSVKRVVPAWVFQAGTTGLIAGASTYSFEAAPIVV
                     DGVMFVSGWDGWVWALDAKTGVEIWRYKHAVPFDVSLCCGNVNRGVAVAQGKVFTVTPN
                     ARLLALDATTGKRVWDKTYGDVRAGESATLAPLVVKNMVVVGSSGGEFGVRGHLDAFDL
                     ASGEHQWRCYTVPKPGEPGSETWPADGEAWARGGANCWVTGTFDPETNLLYVGTGNPAP
                     DFDGGVREGDNLFTDCVIAVDVDSGQIRWHYQCTPHDVWDYDSIAECILFERDGRKLLG
                     HFDKNGYFFVLDRTNGARVGITPFVDRITWGAITRDGRVTAKAYPDKEGEPVHFYPGPA
                     GAKEWTHAAYSPKSELFYVPVQDTGATATRRRREFKESIPYWGAGVQVDIEDMAGSVSA
                     FDADGDEKWRWRNELPMCASVLATGGDLVFAGEPSGEFNALDARTGQMLWQFQCGSGHH
                     SSPTTYTVDDRQYVAVPVGWGGWAEGFLPGMLGAGHGSALIVFALPDWS"
     gene            complement(12661..13122)
                     /locus_tag="CHF15_RS42150"
                     /old_locus_tag="SAMN05216252_15012"
     CDS             complement(12661..13122)
                     /GO_process="GO:1901661 - quinone metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559512.1"
                     /locus_tag="CHF15_RS42150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_15012"
                     /product="MSMEG_3727 family PQQ-associated protein"
                     /protein_id="WP_089229245.1"
                     /transl_table=11
                     /translation="MTTMQERSDLLDKIGLAEQNKAALGQVLGTGSIGYAAETSDGTMR
                     ATIRIHPDELTWDPSILVMPHGGDIELELVNDDLNTHCALLPSNGDRKFIWLVNHSRGR
                     ATLNLDGPGYYWYCSPTGNDEGRGLTGAIVVLGEAPPEARLDRPEQPRP"
     misc_feature    13219..13233
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.23"
                     /tool="antismash"
     gene            complement(13393..15573)
                     /gene="katG"
                     /locus_tag="CHF15_RS42155"
                     /old_locus_tag="SAMN05216252_15013"
     CDS             complement(13393..15573)
                     /EC_number="1.11.1.21"
                     /GO_function="GO:0004096 - catalase activity [Evidence
                     IEA]"
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="katG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559511.1"
                     /locus_tag="CHF15_RS42155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_15013"
                     /product="catalase/peroxidase HPI"
                     /protein_id="WP_089229264.1"
                     /transl_table=11
                     /translation="MGAADNRDWWPGRLDLGILRKHPTRSNPMGADFDYAAEFRTLDLD
                     ALARDVDEALTTSQDWWPADFGHYGPLVIRMVWHCAGTYRVHDGRGGAGAGMQRFAPLN
                     SWPDNRNLDKARRLLWPVKKKYGRKISWADLMVFAGNRALETMGFTTFGFAGGRADVWE
                     PDEDVYWGPEHAWLGDERHRGVRELQSPLAADQMGLIYVNPEGPNTVPDPLASARDIRE
                     TFRRMGMNDEETVALIAGGHTFGRTHGAADPGTHLGPEPEGAPLEEQGLGWKSSYGTGK
                     GADTISSGLHGTWTPTPTTWDNSFFETLFGYEWDLELSPAGLWQWIPRDGGGAGTVPDA
                     HDPATTHAPTMLTTDLALRADPAYEPISRRFLDHPDQLANAFARAWFKLTHLDMGPVHR
                     YLGPLVPRETLPWQDPVPAVDHELVGAADIAALKSRVLASGLSVAQLVSTAWASASTFR
                     ASDRRGGANGARIRLEPQRGWEVNDPATLAHVLRTLEEIQESFNGSQAGDTRISLADLI
                     VLGGAAAVERAAETAGHAVRVPFVPGRTDATQEWTDVESFAPLEPAADGFRNYCGGNGR
                     LPPEHLLVDRANLLDLSAPEMTVLVGGLRVLGANHRRSQLGVFTSQPGSLTNDFFVNLL
                     DTGTAWEPASTAAETFVGRDRGTGEVKWTGSRVDLVFGSNSELRAVAEVYAGDDAREKF
                     VKDFVAAWHKVMSLDRYDLVRSSRRGHMGDER"
     gene            complement(15701..17095)
                     /locus_tag="CHF15_RS42160"
                     /old_locus_tag="SAMN05216252_15014"
     CDS             complement(15701..17095)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671050.1"
                     /locus_tag="CHF15_RS42160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_15014"
                     /product="DNA-binding protein"
                     /protein_id="WP_089229246.1"
                     /transl_table=11
                     /translation="MRDTHRLEPDSANLGSGPVLAAWERFVQGEDHVPGVRPLVAISWH
                     RCREQYRVDPHLTRAPVAVARPDHTPEHDVVFAELGFRAAAVAHEVGSLGGVVTVADAT
                     GRILAAWGDHATLVRAGDCNLAPWFCWSERAVGTNGMGTALEAHGPVPIRGAEHWCQAF
                     HDWVCAGIAVRDVVTREPIAVLNVSCWRGGLPAAVESWLASAVTMTRYPLKSRARDSGA
                     ELVAAYTEARATTGAALAAVDTAGKVVIADDMAGVLLGVPAHTPAIDPTLRWNPGLPEF
                     IAAARYAGRQAVHDRDWVGSTQIFAHLADEPTSISFRPVFSSGHLIGNLVLFGVSDGAR
                     LPPTEGPARPRVPPRRLVALRDNRMVLLRLPEVSFAESHGSDVWLSTDQGRLRAASLSL
                     DRLDSDLADVGFLRVHRRYVVNLSRIREIERGLKGELSLVMEGRTNEMVPVSRRNAPAV
                     RRALNL"
     gene            complement(17295..17915)
                     /locus_tag="CHF15_RS42165"
                     /old_locus_tag="SAMN05216252_15015"
     CDS             complement(17295..17915)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF044444.2"
                     /locus_tag="CHF15_RS42165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_15015"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_143681773.1"
                     /transl_table=11
                     /translation="MPSITRRRSAKLGRPTSAEADVLAATQRLLAGGATFTELGVQQIC
                     TEAGVARSTFYSHFRDKTDLLLRLAGRLMATSFDVTSAWQPAAGVEGLEEAFLQVIQVY
                     RRHAAVRRALAEVATYDSAVRDYFTAELHQFTDWTIKILRAEQEAGRTPAGLDPVSATR
                     IIVTGGERALTDQVTSADPASDPAFARELAHTWWHGVYRRPGT"
     misc_feature    complement(17959..17969)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            18100..19140
                     /locus_tag="CHF15_RS42170"
                     /old_locus_tag="SAMN05216252_15016"
     CDS             18100..19140
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559508.1"
                     /locus_tag="CHF15_RS42170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_15016"
                     /product="aldo/keto reductase"
                     /protein_id="WP_089229248.1"
                     /transl_table=11
                     /translation="MKYRLLGRTGVWVSEISLGAMTFGGKDHPVYGTHGALGQEDVDRV
                     VGAALDAGINFLDTADVYADGESEELLGRAVGRRRRDVVLATKLLAPVGPGPNDQGLSR
                     LHVMRALEDSLRRLGTDYIDLYQIHNHDHLTPVEETLSALDDAVRQGKVRYIGCSNLAA
                     WQISKALGISALHHQAAFVANQTHYSLVARDAEHELVPLAEDAGLGLTVWQPLAGGFLT
                     GKFDRGGATTEPDSRRARNGFDFVPFDEERGFAVLDAVRAVAARHEVGPARVALAWLLA
                     QRAVTSVIVGVRTVEQLADNVAAGALTLTEQDLAELDEASRPPALYPHWIQQWFAPTRI
                     PAGNLA"
ORIGIN
        1 caagctgcgc gacgacagca aggcgacggg ttccggcccg tacaagctgg actcctacga
       61 ggccggcaag gaagcggtgt tctcggtcaa cggggactac caggggtcgg cggagatccg
      121 caactccggt atgacgatga agttcttcgg tgacgagccg gcgctgaaga aggcggtcga
      181 ggacgggtcg gtggacctgg cctaccgtgg tctggactcc gccgacatcg cctcgctgca
      241 gagcagttcc atagccggcg acaccgggat ccaggtcgtg gagggcaccg gcgccgaggt
      301 ccagcacctg gtgttcaacg tcgaggatcc ggtggtgggc aacaaggccg tgcgtcgcgc
      361 ggtggcctat ctgatcgacc gcaaggcgtt catccgcgac gtctaccagc gcaccgcgag
      421 cccgctgtac tcgatcgtgc cggcgggcat caccggtcac aacaccgcgt tcttcgaccg
      481 ctacggcgag ggcggggaca aggccggggc gcaggccgcg ctgtcgcagg ccgggatcac
      541 cgacaaggtc tccttcacgc tgtgggcgac gccggtgcgt ttcggcccgg gcacggtggc
      601 cgagctgaag gcgatcgcca agcagctcaa cgacagcggc ctgttcgacg tggacgtcaa
      661 gaccaccgac gccgaccagt acgccaagga catcgaggcc ggcaagtatg cggtctacgt
      721 acgcggctgg gtcccggact acccggaccc ggacaacttc accgccccgt tcttcggcga
      781 cggcaacgtc ctgggcaaca actacgtcaa caagaagatc accgacgaac tcctcccgcg
      841 caccgccgcc gaggccggcc gcgccgccac ctccaccgac ttcgaggacc tgcagaacgc
      901 ggtcgccgac gacgtgccga tcatcccgct gtggcagggc aagcagtacg tcgtgtccag
      961 ggacaacatc aacggcctgg agtggaccct cgacccctcc accgtcttcc gcttctggga
     1021 gatccagaag ggtgtgacgg agtaaccggc gcactgatga cggatgtcgt cggccggcgg
     1081 ggaccggggc ggggtgctca cgccgcactc acacgacgac ggccacgatg gacgcagacg
     1141 cggcagccgc gcaaccctct tgcggctgcc gcgtcccggt tcggggacca gggagcgcgg
     1201 ccccgcggcc ggttcccgga cgaccggtga acggtcaggt gagggcgctg tcgtggcgcg
     1261 ccgcggtgag cgctgtctcg gtgtcggcgg tggccaggtc ggcgttgatg tgggcgccgg
     1321 cgagcgcgcc ggccgccgcg gaggcgccga cctgggcggt cggatcggtg gcgttgccgg
     1381 ccacccacac cccgggcact gcggtggtgc cggcgatgcc ggactcgaag gagcggcccg
     1441 ccccgcccgt caggtcccgc atcggaagcg ccaggcccac cagcgcggcg aggacgccgg
     1501 gaaggtgtcg ccctgacggt ttgcgtctgc cgcagctcag cggccatcgc cttgcgcttt
     1561 ccggcagcct cggggccggc cgcccacggc ccggtcagcg tgacggccat gagccacccc
     1621 gcccgcaggc cgcgcaccac ggcgcccccc acgtccatgt ccacggccag gagaacgggc
     1681 acgagcacga ccacgacacc gccggccagg cggagctcct cgacctggac gcggaagtgc
     1741 tcgccgaaca caccgcgtcc atcacggcat ggctgccctt cgaggaccgc ccccgccgca
     1801 tcgtcgacct cggctgcggc acaggagccg gaaccctcgc cctgctccgg cgcttccccg
     1861 cggcacaggt gacggccgtc gactcctcgg ccccgcacct gcaccgcctg cgggcgaacg
     1921 cggccgcggc cggaatggcc gaccgcgtac gcctggtccg agccgacctc gacgcaccgg
     1981 cctggccgga cctcggcgcc ccggaactgg tgtgggcctc ggcctccctg caccacatgg
     2041 gcgaccccga caaaaccctg cgcgaggtcc acgacttcct ggccccgggc ggccttctcg
     2101 ccgtcgtcga gccggtcggc ttcccccggt tcctgcccga ggacgccccg gccgacgccc
     2161 cgggcctgga ggagcgctgc cacgccgcac tcggccacca ccacgccgag tacgtccccc
     2221 accgcggcgc cgactgggcg ggcaagctga ccggggccgg cttcgccgtc gaggccgaac
     2281 gcaccctggc cgtcgacatc gccccgcctc ccacggagac cgtcacccgc tacgccctcg
     2341 cgaccctgcg ccgtatgcgc gacgccgtcg ccgtcgccgt cgccgtcgcc accgccctga
     2401 cgccggacga cctgacggcc ctcgaccgcc tgctggacgc cgagagcccc gacggcattc
     2461 cgcgccgcac cgatctgcgc gtgcgcaccg aacgcgcggt ctgggccgcc cgccgcccct
     2521 caagcacccc gtggcgccgg cgccgggccg tgcaccgtgc aggcacgggc aaagcgctgt
     2581 gcacgatcgg gcaaggtgcc gggtcgtgtc cctccctacg gtcgaggtgt cccatcacga
     2641 gtggggcgtc gatgcgccgg ccgggaaccg ctcggggatc cgtcggtctc cggccccgcg
     2701 cggaccgcga gggagtgacg ccgatggcgg acatcgaaca gttcgaggag gggcaggacg
     2761 aggggaaccc ggtgcggtac ctggccgccg ccagcgtggc ggcgtggatc ctggcggtgt
     2821 gcgcggtgtg cgtgatcctg ccgctgtact cccatccgag cctcgcgtgc ggcctggcgc
     2881 cgctggtcac cgcggggacg gcggcgatgg tgctcggaaa cgtgaaggac cgctaccgct
     2941 gcagggcggc gcgggcgcac gccgtctcgg acaccgtgcg gcgggtgctg ctgcggccgc
     3001 tccccgggcg tatcggcgcc ctggggctcg cctccatcta ccggccctgc gggggccggg
     3061 gtcaggtcgg cggcgacctc tacgcggtcg cccgcgcggg cggggcgacc cggctgatca
     3121 tcggcgacgt gtgcggcaag ggcctgccca ccttcgagga cgtcgcggcc gtgctcggcg
     3181 ccttccggga atgggcgccg cgcgcggcga ccttggccga gttgtcggcg cgtctggagg
     3241 agagcttcct gttccacctg gcggagagcg acgacctctc ccgtgacaag gaagagcgat
     3301 tcgtcacggc gctgctgctg gaggtgcggg acggcgagcg gttcgcccgc atggtcaacc
     3361 acggccatcc gcctcccata cgcgcccgcc gggggagtgt ggccctggtg gcgggatgcc
     3421 cggctcctcc gctgggcctg tacggtctgc gcgagtgcgg agccatcgag gaacgcttcg
     3481 aactgtgccc cggggacacg ctgttgctct acaccgacgg gctgatggag gcccgcgacg
     3541 ccgccggacg ctgctacccg ctgctggagc gggcgaccgc gtggcgatgg gtccggcagg
     3601 gcgcgccgag tcaggtgtgc ctgccggacg tgctggggga gatcctcgag gatgtcgtcg
     3661 accacgccgg cgcgctcccg accgacgacc tggcgatggt ggccctgacg cgcgtggagg
     3721 aaccgggcgc gcccgtgctg acctggccgg ccggtgaggc gtggcgcgag gacgcggggc
     3781 agtggcggca ggactgacca cgcgccgcgc tgccggggga ggaggccggt gttccgcggg
     3841 ggtgcagccc gcggaacacc ggcctgccgt cgttccgcgg gggatccggg ggacgtgccc
     3901 gggggtcgtt tgacccggac ggcagccgca cgcatagggg tgtttgaccc atgcgtgggg
     3961 catgcaccca ctgccacagt ggcggggcgg gaagggacgg ccgggtcctc tgcgaagccg
     4021 gtcgtggagg ccggctcgac agtgctgccc tgggggcggc cgaccggccc gcatcccgta
     4081 cgaaccgggc ctgacgggac ccgttgccgc gcggcggccg tccggggcgc aggcgctgat
     4141 atgccaagca agcaccgcga acagttcgtt atcagttcat ttctctgaaa aaggggcgcc
     4201 atagcgtctc gggggactgc acaccgatcc gcaggggaac ggtgcgagga aaggcgcagt
     4261 acatggaaac gacaagaggg tccgacgggc cggaccgtgg gtccgaggca ctgacccgcc
     4321 ggaggttcgt ggtcatggcg ggttccgccg tcgtggcggt cagcgtcggc gcgagcaccg
     4381 cccaggctgc cacggggccc gcttccgagc agggcgggaa ggtcaaggcg gcgggccgga
     4441 cgtccgcgct caaccgggcg aaggcgccca cgggcaagtg gctcgcgggt gacacccacg
     4501 tccacgacga ccactcctcg gacggcagcg gaccccgcca gacgtcccac cagacactgc
     4561 ccggaaacct tcccgtcggc gaccagatcg cgcagggcga gaaggccggc ctcgacttca
     4621 tgcccctgac cgaccaccgg acgtacgacc aggtctggga cccccagtgg aagtcgtccg
     4681 aactgctgct gctcccgggc gaggaggcga acggctcgcc ccacgccatc gtgctgggca
     4741 atgtggacgt gatcgtggac ggtgccaacc cgcccggctc cgcggccttc cgccacgtac
     4801 agcagtcggt ctgggacgcc cacgcacagg gtgccgtgtg gtcgcaggcc caccccgacg
     4861 acggcgagta cacgccggcg acgggcccga acgccaacgc cagcgtccag ggcgcggacc
     4921 tcgccgaggt gctcaacgtc tccaccggcc cggacgagca ggtcgagtac gcggagaacc
     4981 ggtggaacgc cggtttccgc ttcggtgtgg cggcggcgag cgactgccat ttccgcgagc
     5041 tgtgggacgt cgacgccccc ggcacgccca ccacccacgt cttcgcggcg aagcgttccg
     5101 tcctcggcat cctcgacggg ttccgcggcg gccgtacgac ggtcgcgcag aacaccgccg
     5161 gtccgttcct gacgatcgag gcggacgccg acggtgacgg tgtgttcgaa gcgatcggcg
     5221 gcgacgaggt ggtcgtggcc gaccgcaagc tgcccaagaa ggccacactg cgggtgaagg
     5281 tgaagggcgg caagggaacc accgtccacg tgtacgccgc ccccggccgc tcggcgggtc
     5341 cgatcgcgag ctaccggccc cagcgggcca acgagaccta cgatctgccg ctcgtcctca
     5401 agggcacgga ccacggctgg ttccgggtcg aggcccgttc ccccggcagc ccctccggct
     5461 ccgacgccga cccgaacctg ccggaccagc tccggggcgc cacctcgccg atcttcgtct
     5521 cggtcggcgc tcccgccgtc ccacggcccg agatcccgct cccggccgcc gacaccgccg
     5581 gtgacaaggc ggaactcgtc accggcgacc tgggcacgtt caccggattc tccgatgtcg
     5641 cggtcgtcgg cgacgtcacg cacatcgtgg cggaggtgca cgaggaccac gcgagcaagg
     5701 tggtctaccg ccggctcgac ggcaagggac ggatcaccaa gtccgtcacc ctttccggcc
     5761 gttcggccac cgcgcgcttc ccgcgcatag ccgccgccgc caaggacgtg tgggtggtct
     5821 ggcaggacga gcagggcaag gagcagccgc accgtccggt gatcctgctg gcgcacagcg
     5881 cgaacggcgg cagctccttc aaggccccgg acaagatcag caagggcaag gggcgcgccg
     5941 tccacccggc gctggcactg gtcggcgacg gccacccgct ggtcgcgtgg tccgacaaca
     6001 gcggcggcgc gttcgacgtg tacgcgcaga tcgtcggcgt cgacaaggcc gcggtgaaca
     6061 tctccgcggc cggcaaggtg accagtcccg gcgttcccgg ggacgcgcgc tccccgcgct
     6121 accccgcctc gctgttcccg gccgtagccg tccacgacgg ccggcacgcc gtgatcagct
     6181 ggcaggacga ccgctacgac ccggacccgc tgtggaccgg ccacaccccg cccgccggcc
     6241 agccggccgg cggcggcacg gaccccgaca actggcaggt gctggcgtcg gtacgcaagg
     6301 caccgggccg cgcctggggc aacccggtcc aggtcagcaa ggtcggcgac cgctccgacc
     6361 ggcacccggg cctgaccgtc gacgaggacg gcaccttcgt cgcgatctgg gagagcggcg
     6421 cgctgcagag ctccggcgcc aacctccagc tccgggccgg ccgctccacc gacggcggcc
     6481 tcacgtggac ggcgttcgag aacgtcggcc tcgacgccga cgcgatgagc cagcgggcca
     6541 agctcggtgt ggaccccgac ggtacggtcc gcgcggtctg gtacgactcc cgctcgaccg
     6601 actggcggtg gaagatcttc accgccaccc tcgacggagc gaagggctgg tccgaggcca
     6661 cccaggtgag tcaccggggc aacaacacct ggcccgcact gcaccgcggc gtcgtggtgt
     6721 tcaccagcga ccgcggcgcg acccgtactc agcgcgacga gacgcagcag atcttccgga
     6781 cgaagctggt ctgaccggcc ggcgtgcggc ccgcacggca ccgccttccc cacgcgcctc
     6841 ggacatgcag tgcgcccggt ggcgcgccgg gggaggcggt gccgtcgcgg ggctgttcca
     6901 tgcgtcgatt ggccccctgc gctgcggcga gtagtgtgga aaacgcgccg gaagtcggct
     6961 ctgcggaggg aatttcgcgg cccgtccggg acgtcgttcc ccacctgacg gatggttcac
     7021 gcggtggatc cggcgccgcc gccgtccgtc gtcaccgggc ggcgacatcg tcatgatctg
     7081 ggaaatactg gtcctgggct tcgtactcag cctcgacaac ttccgggtgt cgatcgcgct
     7141 cggtaccgtc ccgttcggtc tgaagcgcgc ggtgcaggtc gcgctcacct tcggactgtg
     7201 ggacgccgtc atgcccctgg tcgggctgtt gatcggtcgc cggctcgggg agtccgtcgg
     7261 ggacgtcgcc gacttggtgg gcgcggccgc actcggtgga tacggtctct acctcgtcgt
     7321 ctcggccctt cgcaaccccg agccggacga gttggaccac ccgtgggcgt tgttcggcat
     7381 cccgttgacg ctgagcctgg acaacctgct cgccggggcg agcctgggtc tcctcgggct
     7441 ctcgccgtgg ttctcggccg ccgtcttcgg catcatgacg gcggtgatgt cgctggtcgg
     7501 gctgcagctc gggcgggtca cggcgcgact gatccggatc cgctcggacc tgctgagcgg
     7561 ggtcaccctg atcatcgccg ccgtggcgct gccgttgtgg ttcggtgcct agcccgatcc
     7621 gcgcgggatc cggtccggcc ggcgggcccg gtgcggccgg gggaccagcg cgggatcgcc
     7681 cgcccgcgag cccgtgttgg cggcctcgac cgccccggcg acgaggtggt ggtcgggcga
     7741 caggtgacag accggatcgg tacgggccgc gtcgccggtg agcaggaacg cctggcagcg
     7801 gcagccgccg aagtccacct cccgccggaa gcagctccgg cagggctcgg gcatccagtc
     7861 ggtcccccgg aaggcgttca tcaccgggga ctcggcccag atccgcgcca gcgagtcctc
     7921 ccgcacgctg gcccgcggca acggcaggga ctgcgcggcc gggcagggca gcacgtcgcc
     7981 gttcggcgtc acggtcagct gccgggacgc ccagccgccc atgcagggct tcgggtagcg
     8041 gctgtagtag tcggagatga cgtagatgac gtccatgcgg tcccgcaacc gttcacgggc
     8101 ggcccgcacg acgacctcgg cggcgtcgag ctgggcccgg ctgggcagca acgcggcgcg
     8161 gttgcgccag gcccagccgt agtactgggt gttggccagc tccagccggt ccgcgcccac
     8221 ctcctcggcc agggtgagca catcggcgac gcggtcgatg ttgtgccggt gcagcaccac
     8281 gttcatggtc aggggccagc ccagctcctt gaccagtcgc atcgcctcga tcttgcgccg
     8341 gaaggagggg atgccggcga tccggtcgga cacggccgcc tcgtcggcct ggatgctgat
     8401 ctgcacgtgg tccaggccgg ccgcccgcag tcgctcggcc ctcggacggg agagccccac
     8461 ggcgctggtc acgaggttgg tgtagaggcc caggtcgtga gcggccgccg cgatctccac
     8521 caggtcgcgc cgcagcagtg gttccccgcc ggacaggtgg cactgcagca cccccaggtc
     8581 cccggcctcg gccagcaccc gccgccactc gtccagggcc agctcgtccc ggtagccggc
     8641 catgttcagc gggttggagc agtacgggca ggccagcggg cagcggtagg tgagctcggc
     8701 gagcaggccg aacgggctat ccatcggtga gctccatcca gcgccgggcg acgagccggg
     8761 tcaggaaccg ccgcacctcg tccccgggga cggcccggta gcgggtgccc agctcggtca
     8821 cgatctccgc cacggtgtgc cgcccgtcgc acagttcgag gatcgccgcg ccgctgccgt
     8881 tcaggaccac caccgtctcg gggtgcagca ggatccggcg ctgtctggtc cggcagaagg
     8941 tgagccggac atggcgtgcc agcaggggcc ggtcggagcc gcacacctcg acaccgggcc
     9001 cggtcctggt cccggccctg gtcgttccgg tggaagtcgc gtccatggcg gtcacttcgg
     9061 gtaggcctgc tcgatggagt ccatcagact ccacaggacg tcgcacttga acgacagcgc
     9121 gtcgacggcg cgggcctggg actcggcgga gacgcagtgc gacgtgacca cctggagggc
     9181 gtgttcgcag tcacggggag cctgctccag gcgggtgcgg aagtaggcga ggccctcggg
     9241 gtcgatccac gggtaccagc gctcgaacgc ggccaggcgt gcggccatca ggtcgggagc
     9301 gaacagctcg gtgagcgagg acgccaccgc ctccacccac gggcgggtcc gggcgaagtt
     9361 cacgtaggcg tccacggcga accgcactcc gggtaccagg tgccggtggt cccggacctc
     9421 ctcacgggtc agccccgccg cctcgccgag gcgcagccat gcctcgatgc cgccctcgcc
     9481 ggcggcggtg ccgtcgtggt cggtgatccg ccggagccag cgacggcgga actcgaggtc
     9541 ggggcagttg gagaggatcg cggcgtcctt gcgggggatg ttctcctggt agtagaagcg
     9601 gttggcgacc cagccgcgga tctgacgagg gctcagcccg ccggcgttca tcacgacgtg
     9661 gaacgggtgc tggtcgtggt agcgccgcga gtgggcccgc aacgtctcga cgaagccgtc
     9721 ggttccgctg ctcctgatcg tcctcgcggg agttgtcgtc acggttctac acctggacct
     9781 cgaggccgtc cgtggccacc tctatgccgc tctcccgcag tgcgcgccgc tcgggcgcgt
     9841 cctccaggag aacggggttg gtgttgttga tgtggacgag gatcgtccgt cccgcggcca
     9901 gcgacgggag ccgggacagg ctgccgtccg ggccgtctat gggcaggtgg cccatctccc
     9961 gggccgtctt gcccgccaac ccgagccgta cgagttcgtc gtcgcgccag caggtgccgt
    10021 cgaacagcag gcatccgcag ccttcgatct ccgtgcgcag cgctgccgtc agcgattgcg
    10081 ccgccggcag gtagaccagc gtgcccccgg tgtgctcgtc ggtcagccgg tagcccacga
    10141 cacggccgtg gtccgcctcg cccccgaacc gggcgcgttt ggcggtggga acgtcgaacg
    10201 cacggcagga cagcccgttc gccagcgtca ggtcggtgcc ggggaccacg gcccgccact
    10261 cgacggtgca gtagcgccgc agcgtggtca ggattcccga gccgtcacac agggtcttgt
    10321 gtgtcgccgg tgtggcgtac acccgcaggg cgcgggcctc gcgcagcagc agcaggccca
    10381 gtgtgtggtc cagttcggcg tcggtgagca gcaccgcctc cagcggcgtc gtccggtcgc
    10441 cccgcgggtg caggcccggg aaggcctcga actgggcgcg caggtcgggg gaggcgttga
    10501 ggaggaacca ccggcggtgg tcggcgctga cggcgatcga ggactgggtg cgcggcggtg
    10561 cggccccgga gcggaccgcg gcgcacaccg cgcaaccgca gttccactgc ggggagccgc
    10621 ctcccgccgc cgaccccagc actcgcagca gcacgccggt actcccttcg tccgatgtcc
    10681 gcctccgggc cggtcgatcg tcggcccggc cgtccgtgga cgtcccaagc cgtggggggc
    10741 gccgccggac aacgcggtcc ggcgtgcccc acgtgcgcta gtcctcgagc cgggcgacgt
    10801 aggccgtcac ctcggccgcg accgcgatct cctcgaactc gggcgtctcc cacacggcga
    10861 gctgggattc cagctgcgat tccatgggct gggattccat gggctcacct cctttccgac
    10921 cggatacggc aggtccgggt cgcgcgctac gaccaatccg ggagggcgaa gacgatcagg
    10981 gcgcttccgt gccccgcacc gagcatgccg gggaggaatc cctcggccca cccgccccag
    11041 ccgaccggta cggcgacgta ctgcctgtcg tcgaccgtgt aggtggtcgg gctgctgtgg
    11101 tggccgctgc cgcactggaa ctgccacagc atctgcccgg tgcgggcgtc gagcgcgttg
    11161 aactcgccgg acggttcacc tgcgaacacc aggtcaccac cggtggccag caccgaggcg
    11221 cacatcggca gttcgttgcg ccagcgccac ttctcatcgc cgtcggcgtc gaacgcgctg
    11281 acggaccccg ccatgtcctc gatgtccacc tgaacgcccg cgccccagta cgggatgctc
    11341 tccttgaact cccggcgccg ccgggtggcc gtggcacccg tgtcctggac ggggacgtag
    11401 aacagctcgg acttcgggct gtaggccgca tgggtccatt ccttggcgcc ggccggaccc
    11461 gggtagaagt ggacgggttc cccctccttg tcggggtacg ccttggccgt cacccggccg
    11521 tccctcgtga tggcccccca cgtgatgcgg tccacgaagg gggtgatccc gaccctcgcc
    11581 ccgttcgtgc ggtcgaggac gaagaagtag ccgttcttgt cgaagtgccc gagcagtttg
    11641 cgcccgtccc gctcgaacag gatgcactcg gcgatgctgt cgtagtccca cacgtcgtgc
    11701 ggggtgcact ggtagtgcca gcggatctgg ccgctgtcga cgtcgacggc gatgacgcag
    11761 tcggtgaaga ggttgtcccc ctcgcggaca cctccgtcga agtcgggcgc cggattgccg
    11821 gtgccgacgt acagcaggtt ggtctccggg tcgaacgtgc cggtcaccca gcagttcgcc
    11881 ccaccacgtg cccaggcctc gccgtcggcg ggccaggtct ccgagcccgg ctccccgggc
    11941 ttgggcaccg tgtagcagcg ccactggtgc tcaccggagg ccaggtcgaa tgcgtcgagg
    12001 tggccgcgta cgccgaactc gccgccggaa ctgccgacga cgaccatgtt cttcacgacc
    12061 agcggggcga gcgtggcgct ctccccggcc cggacgtcac cgtaggtctt gtcccagacc
    12121 cgctttccgg tggtggcgtc gagtgcgagc agccgggcgt tcggcgtgac ggtgaagacc
    12181 ttcccctggg ccacggcgac cccgcggttg acgttcccgc agcacaggga cacgtcgaag
    12241 ggcacggcgt gtttgtaccg ccagatctcc acaccggtct tcgcgtcgag ggcccacacc
    12301 cagccgtccc agccggacac gaacatgacc ccgtcgacga cgatcggggc ggcctcgaac
    12361 gagtaggtcg acgcgcctgc gatcagtccg gtcgtgccgg cctggaagac ccacgcgggg
    12421 acgacgcgct tgacgctgtc cgtgttgatc tggtccagcg ggctgtaccg ctgcccgttg
    12481 tacgcgccgt agtaggtgag ccagttgtgg ggctcccggc gggcgttgag tatgcgctcg
    12541 tagtcgaggc cggccaccac cggcggcgcg acctccccgc ccgcgacctt gccgctcagc
    12601 agcccctggt cgacggcttc gcccgcgtcc acgtagtcga cggacatctc ctcctccttc
    12661 ctacggccgc ggttgctcgg ggcggtcgag gcgagcctcc ggcggagcct ctcccaggac
    12721 gacgatggcc ccggtcaacc cccggccctc gtcgttgccc gtgggcgagc agtaccagta
    12781 gtagcccggt ccgtcgaggt tgagggtcgc ccgtccgcgc gaatggttca ccagccagat
    12841 gaacttccgg tcgccattgc tcggcaggag cgcgcagtgc gtgttcaggt cgtcattgac
    12901 gagttcgagc tcgatatcgc ctccatgggg catgaccaga atggacggat cccaggtcag
    12961 ctcgtccggg tggatccgaa tcgtggcccg catggtgcca tccgatgtct cggcggcgta
    13021 tccgatgctc ccggttccca gcacctgacc cagcgccgcc ttgttctgtt cggccaaccc
    13081 gatcttgtcc agcaggtcgg atcgctcctg catggtcgtc atcggggcgt cactctcctc
    13141 atacagagat cgccgtgttc ttcgcttcgg ccgcgccgac cgaggtacgc cgcggccggg
    13201 tgcacacctt ccctcgagaa tgttctccga attgacttcg tcggattcat cgcatcggag
    13261 atccactgcg ccgaattgag cgcgcgggaa agcggatgat ttgccgcctg atcaaaacgc
    13321 tacgccggac ggatcacacc gacaagggtg ggcgcgagtg cgggccggct catgccgttc
    13381 gtcggcgacc ggctaccgtt cgtcgcccat atgcccccgt cgggaggatc gaacgaggtc
    13441 gtaccggtcc aggctcatga ccttgtgcca cgcggcgacg aagtccttca cgaacttctc
    13501 ccgggcgtcg tcgccggcgt agacctccgc gacggcacgc agctcggagt tcgagccgaa
    13561 gacgaggtcg acgcggctgc cggtccactt gacctcgccg gtgccccggt cgcgccccac
    13621 gaaggtctcg gcggccgtgg acgccggctc ccatgccgtg cccgtgtcga gcaggttcac
    13681 gaagaagtcg ttggtcagcg atccgggctg cgaggtgaac acgcccagct gcgaccggcg
    13741 gtggttggcg cccagcaccc gcaggccacc caccaggacg gtcatctcgg gggcgctcag
    13801 gtccagcaga ttcgcgcggt cgaccagcag gtgctccgga ggcagccggc cgttgccgcc
    13861 gcagtagttg cggaacccgt ccgcggccgg ctcgaggggc gcgaaggact ccacgtcggt
    13921 ccactcctgc gtggcgtccg tgcgtccggg aacgaagggg acccggaccg cgtggccggc
    13981 cgtttcggcg gcccgctcga cggcggcggc cccgccgagc acgatgaggt cggccagcga
    14041 gatcctcgtg tccccggcct gggatccgtt gaaggactcc tggatctcct ccagggtgcg
    14101 cagcacgtgt gccagtgtgg cggggtcgtt gacctcccac ccccgctgcg gctcgaggcg
    14161 gatgcgcgcg ccgttcgccc cgccgcgcct gtcgctggcg cggaacgtcg acgccgacgc
    14221 ccacgcggtc gagacgagct gggcgaccga cagcccggag gcaaggacgc ggctcttgag
    14281 cgcggcgatg tccgccgccc cgacgagctc gtggtccacg gcggggaccg ggtcctgcca
    14341 gggcagggtc tcccgcggca ccaggggtcc gaggtagcgg tggaccgggc ccatgtcgag
    14401 gtgcgtcagc ttgaaccagg cccgggcgaa cgcgttcgcg agctggtccg ggtggtccag
    14461 gaagcgccgt gagatcggct cgtacgccgg gtccgcgcgc agtgccaggt ccgtcgtcag
    14521 catggtcggg gcgtgcgtcg tcgccgggtc gtgggcgtcc gggacggtgc cggccccgcc
    14581 gccgtcccgc gggatccact gccacaggcc tgcggggctg agctccaggt cccactcgta
    14641 gccgaagagc gtctcgaaga agctgttgtc ccacgtcgtg ggggtcggcg tccacgtgcc
    14701 gtggagtccg ctggagatgg tgtccgcgcc cttcccggtg ccgtagctgc tcttccagcc
    14761 caggccctgt tcctcgaggg gagcaccctc gggctcgggg ccgaggtggg tgcccgggtc
    14821 ggccgcgccg tgggtcctgc cgaacgtgtg gccgcccgcg atcaaggcga ccgtctcctc
    14881 gtcgttcatc cccatgcggc ggaacgtctc gcggatgtcc cgggcggagg cgagcgggtc
    14941 cggcacggtg ttcggtccct cggggttgac gtagatgagg cccatctggt cggcggccag
    15001 tggactctgc agctcccgga cgccgcgatg gcgttcgtcg ccgagccagg cgtgctcggg
    15061 gccccagtag acgtcctcgt cgggttccca gacgtccgcc cggccgcccg cgaatccgaa
    15121 ggtcgtgaaa cccatcgtct ccagggcgcg gttgccggcg aagaccatca gatcggccca
    15181 ggagatcttg cggccgtact tcttcttcac cggccacagc agcctgcggg ccttgtcgag
    15241 gttgcgattg tccggccagc tgttcagcgg tgcgaaacgc tgcatcccgg caccggcgcc
    15301 gccccggccg tcgtggacgc ggtaggtgcc ggcgcaatgc cacaccatcc ggatcacgag
    15361 cggcccgtag tggccgaagt cggccggcca ccagtcctgc gacgtggtca gggcctcgtc
    15421 gacgtcgcgc gccagtgcgt ccaggtcgag cgtgcggaac tccgcggcgt agtcgaagtc
    15481 cgcgcccatg gggtttgacc tggtggggtg tttccgcagg atccccaggt cgagccggcc
    15541 cggccaccag tcgcgattgt ccgcggcgcc gatcgggcgg ccgcggtgcc cggtggggac
    15601 ggagaggccg aggccgcccg cgttgccggc gtccgtccgg tcggcggcgg catccggaaa
    15661 gtcggacacg gggatctcct tccggaggtt gcgtcgtggt tcagaggttc agcgcgcgac
    15721 gcacggccgg cgcgttccgc cgggagaccg gcaccatctc gttcgtccgg ccctccatga
    15781 ccagggacag ctcgcccttg agcccgcgct cgatctcccg gatgcggctg agattgacga
    15841 cgtaccggcg gtgcacccgc aggaagccga cgtccgccag atcgctgtcg agcctgtcca
    15901 ggctcaggga ggcggcccgc aaccggccct gatcggtgga gagccacacg tcgcttccgt
    15961 gcgactcggc gaaggagact tccggcagcc gcagcagcac catccggttg tcgcgcagcg
    16021 cgaccagccg gcgcggcggc acccgggggc gcgcgggtcc ctccgtcggc ggcagccgcg
    16081 ccccgtcgga aacgccgaac agcaccaggt tcccgatcag gtggccggag gagaagacgg
    16141 gccggaagct gatcgacgtc ggctcgtcgg cgaggtgggc gaagatctgc gtcgagccga
    16201 cccagtcgcg atcgtggacc gcctgccggc cggcgtaccg ggcggccgcg atgaattccg
    16261 gcagcccggg gttccaccgc agagtggggt cgatcgccgg ggtgtgggcg gggacgccca
    16321 ggagcacgcc cgccatgtcg tcggcgatca ccaccttgcc cgcggtgtcc acggcggcga
    16381 gcgccgcacc ggtcgtcgcc ctggcctcgg tgtaggccgc gaccaactcc gcgccgctgt
    16441 cccgggcgcg gcttttgagc gggtagcggg tcatggtgac ggcgctcgcc agccagcttt
    16501 cgacggccgc gggaagcccg ccgcgccagc aggagacgtt cagaaccgcg atcggttccc
    16561 tggtgaccac gtcacgcacc gcgatgcccg cgcacaccca gtcgtggaag gcctggcacc
    16621 agtgctcggc gcccctgatg ggcaccgggc cgtgtgcctc gagcgccgtg cccatgccgt
    16681 tcgtgccaac cgcgcgctcg gaccagcaga accagggcgc cagattgcag tctccggccc
    16741 ggacgagcgt ggcatggtca ccccacgcgg cgaggatgcg gccggtggcg tcggcgacgg
    16801 tgacgacgcc gccgaggctg cccacctcat gcgccacggc ggcggcgcgg aagcccagtt
    16861 cggcgaagac cacgtcgtgc tcgggggtgt ggtcgggcct ggccacggcc accggagccc
    16921 tggtgaggtg ggggtcgacc cggtactgct cccggcagcg gtgccaggag atcgccacca
    16981 gcggccggac gccggggacg tgatcctcgc cctgcacgaa ccgttcccat gccgcgagca
    17041 ccgggccgct gccgaggttc gccgagtcgg gctcaagccg atgtgtgtcc ctcatggttc
    17101 tgaaccgcct ctggtccatc cccagtgccc ggcggcgtca gcgcgatccg ctccggtcgc
    17161 cgcctgtggc ggccggacct gcagcggacc ggtcaccgcg ccgcgggcct tgctccgtca
    17221 cccgttccgg gccgtcttgc ttccccccac ggtccaccct agtaccgtcg aggggccgcg
    17281 gacgtcccgt ggggtcaggt gccggggcgg cggtagacgc cgtgccacca ggtgtgcgcg
    17341 agttcgcggg cgaacgcggg gtcgctcgcg gggtcggcgg aggtgacctg gtccgtcagg
    17401 gcgcgctcac cgccggtgac gatgatccgg gtggcgctga cggggtcgag gccggcgggg
    17461 gtgcggccgg cttcctgctc ggcgcggagg atcttgatcg tccagtcggt gaactggtgc
    17521 agctcggccg tgaagtagtc gcgcaccgcg ctgtcgtacg tcgcgacctc ggcgagcgcc
    17581 cgccggaccg cggcgtgccg ccggtagacc tggatcacct gcaggaaggc ctcctcgagg
    17641 ccctcgacgc cggccgcggg ctgccacgcc gaggtgacgt cgaaggacgt ggccatgagc
    17701 cggccggcga ggcgcagcag caggtcggtc ttgtcgcgga agtggctgta gaaggtcgag
    17761 cgggccacgc cggcctcggt gcagatctgc tgcacgccga gttccgtgaa ggtggcgccg
    17821 cctgccagca ggcgctgggt cgcggccagg acgtccgcct cggccgaggt ggggcggccg
    17881 agcttcgcgg agcgtcggcg ggtgatcgag ggcatgtccg gatcctgggt cgtcgcgggg
    17941 ccggggccgg cggggaacgt cacattacac cgcgtccgga catcgtgtag cgtaatttcc
    18001 ggacgcgatg tccggacgtt gcgaacggaa aggtgtgggg cgccctgccc cggccgccgc
    18061 cgcgaccaag cgagtacgtg tgcgtacgag gagtgacctg tgaaatatcg tctgctggga
    18121 cgtaccgggg tctgggtctc cgagatctcc ctgggcgcga tgacgttcgg aggcaaggac
    18181 cacccggtgt acggcaccca tggggcgctg gggcaggagg acgtggaccg ggtggtcggc
    18241 gcggcgctgg acgccgggat caacttcctg gacaccgcgg acgtctacgc cgacggcgag
    18301 agcgaggaac tgctcggccg ggcggtcggg cggcgccggc gggacgtggt gctggccacc
    18361 aagctgctcg ccccggtcgg accgggaccc aacgaccagg ggctgtcgcg gctgcacgtg
    18421 atgcgggccc tggaggacag tctgcgccgg ctggggaccg actacatcga cctctaccag
    18481 atccacaacc acgaccacct gacgcccgta gaggagacgc tgagcgccct cgacgacgcg
    18541 gtgcgccagg gcaaggtccg ctacatcggc tgttccaacc tggccgcctg gcagatcagc
    18601 aaagcgctgg gcatctccgc gctgcaccac caggcggcgt tcgtcgccaa ccagacccac
    18661 tactcgctgg tggcacgcga cgccgagcac gagctggtgc ccctggccga ggacgcgggg
    18721 ctgggcctga cggtgtggca gccactggcc ggcggattcc tcaccggcaa gttcgaccgc
    18781 ggtggggcga ccacggaacc ggactcccgc cgtgcccgca acggcttcga cttcgtaccg
    18841 ttcgacgagg aacggggatt cgcggtgctc gacgcggtcc gggccgtcgc ggcgcggcac
    18901 gaggtcggcc cggcccgggt ggccctggcc tggctgctcg cgcagcgcgc cgtcaccagc
    18961 gtgatcgtcg gcgtccgcac ggtggagcag ctcgcggaca acgtcgccgc cggcgccctg
    19021 acgctgaccg agcaggacct cgccgaactc gacgaggcca gcaggccccc ggcgctctat
    19081 ccgcactgga tccagcagtg gttcgccccg acccggatcc ccgccggcaa tctggcctga
    19141 cggctgccgc tcgggcgccc gtgcggccgg gtgatccgac ggacgagttc cgcgtcagga
    19201 cggggcgagg acgcagaact cgtggccctc cgggtccgtc aggcacgtcc acgggacgtc
    19261 gccctggccg aggtcgaggt cggtggcgcc gagggcccgc aacctggcca cctccgccgg
    19321 cttgtcgtca ccggggtacg gcagcaggtc gagatggacg cggtccggca cggtcttcac
    19381 atcgggcgtg cgcaggaact cgagatacgg gccggcattc tcggcggagc gcaacaccgc
    19441 acgatcgtcg gtcacctccc gcagggtcca gtccatcgcc gagtcccaga accgggccat
    19501 ggcccgcgga tccgcgcagt cgaccaccac ccgggcgatc gggccggtgt cccggtggat
    19561 ctcccggggc tccagcacgc agaactcgtt cccctcgggg tcggcaagga ccgtccacgg
    19621 gacgtcgccc tggcccaccc ggacggacgt cgcaccgaga gcccggaggc gcgcgaccaa
    19681 ctccgcctga tgggtcgcgg agctggtggc gagatcgagg tgcgcacggt tcttcgtcgc
    19741 cgtcttgggt tccggcacgg ga
//
