LOCUS       NZ_FZOF01000021        26343 bp    DNA     linear   CON 02-JAN-2025
DEFINITION  Actinacidiphila glaucinigra strain CGMCC 4.1858, whole genome
            shotgun sequence.
ACCESSION   NZ_FZOF01000021
VERSION     NZ_FZOF01000021.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinacidiphila glaucinigra
  ORGANISM  Actinacidiphila glaucinigra
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Actinacidiphila.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900188405.1-RS_2025_01_02
            Annotation Date                   :: 01/02/2025 02:14:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,793
            CDSs (total)                      :: 8,707
            Genes (coding)                    :: 8,547
            CDSs (with protein)               :: 8,547
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1 (5S, 16S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 47 of 160
            Pseudo Genes (incomplete)         :: 136 of 160
            Pseudo Genes (internal stop)      :: 6 of 160
            Pseudo Genes (multiple problems)  :: 29 of 160
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:25:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 41614
            Orig. end                         :: 67957
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FZOF01000021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26343
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26343
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26343
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16343](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16343
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(440..1816)
                     /locus_tag="CHF15_RS30710"
                     /old_locus_tag="SAMN05216252_12136"
     CDS             complement(440..1816)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963084.1"
                     /locus_tag="CHF15_RS30710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12136"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_245939116.1"
                     /transl_table=11
                     /translation="MPQAAHPPSCAKQLRQAASQRGASNQQIARIIHVHCGVSELRAQR
                     LARGLTLKQTADDLNRIAEGRADAPRTDGDQLGHWESGRRPRNNTIELLCEFFDCTVAD
                     IGFARSAMSPTNVPAIQALIPRSPQKGFTDTDTLAQQVDAARWSVDRTLTAGTVSATQL
                     DLLDEQVLWAREQYVYTPPAPMIETLLRHLAEVDELSAHRQPAAVQVRLSELVAMLATL
                     VADALMKLGQLSRSQSWYATARNAADDSGNAELRARVRAQAAMLPFYYGPLEAAVNLAR
                     EARIICRGRPSATAAFAAAAEARALAKMGDALGADVALRHAASAFEQSGAGGPTDNDAF
                     GFPERRFLLYESGTLTSLGHTSRARRTQDAALRLYPARTGIDPALLSLETAICLARERS
                     AAEACQVAGTAILRITPAHRTPIVEQRAHEVIQALPPGIRDGRAVRELRDILALPPGQV
                     "
     misc_feature    complement(1937..1952)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.42"
                     /tool="antismash"
     gene            2115..2621
                     /locus_tag="CHF15_RS30715"
                     /old_locus_tag="SAMN05216252_12137"
     CDS             2115..2621
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.5"
                     /locus_tag="CHF15_RS30715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12137"
                     /product="ATP-binding protein"
                     /protein_id="WP_089227259.1"
                     /transl_table=11
                     /translation="MTAPTSRQFLTALASGEGVDRVSVHLESTASSVGKARRFVERQLV
                     SWGFPPDEDVVQRVVLTVSELATNAVLHGRSRPPAEDELIEVALSLKPDFALGVAVTDD
                     SDALPLTPTSTSATATRGRGLVLVSALADSWMTAPRQRQEAHQGKDVWAFFRCHETSVA
                     LPRTA"
     gene            3007..3672
                     /locus_tag="CHF15_RS44515"
     CDS             3007..3672
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHF15_RS44515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_143681669.1"
                     /transl_table=11
                     /translation="MADLYENVLWVRQPIAPGRGRPHFAGIHSRRQRRCLQYMLCQVCD
                     VTTFARADGRHLFLLRANGEQPIAEGERTTAGPVCVPCAVQSVAFCPHLRGSYTAALVS
                     YCPTWGVAGVVYDPDTLHPLSAGPDNPLELVAHDDPRISWTLAARYVVSLHGCEPVNVA
                     DLEKAEADTLHPPASGSAPGATVMKGIHPVHRDQPPALLPEGLPRRLPPRPLPAPPGS"
     misc_feature    3699..3714
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.23"
                     /tool="antismash"
     gene            4532..5989
                     /locus_tag="CHF15_RS44065"
                     /old_locus_tag="SAMN05216252_12140"
     CDS             4532..5989
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="CHF15_RS44065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12140"
                     /product="ATP-binding protein"
                     /protein_id="WP_143681670.1"
                     /transl_table=11
                     /translation="MTSAAVGGGWLADSLSIVPASAAAAASGSLVLAVGVWAGVRRIDA
                     RRRTAAQIGQLRHERDRLQQALRDVSDAVAVGRKRVAWAVDQASQGQFARGESAIAPVE
                     SGDLCTDVLASLQCALAEGWQAVLRAAEQQHEALAAEAELADLARSITPRMQSLVNRGI
                     ALIERVERSVEDPDLLHELFQVDHLLTQMRRAGESLAVLGGSTPPEHAQPLLVATALRR
                     AVAEIEHYPRVRIAQQLQPSRPFALPGYVSPSVVHLLAEIMDNAARYSTDKVEVYTTEV
                     RGGLLIEVLDRGGGIPDDKRAVLNDLLARPEAVERRARVKDGQIGLLVAALLARRYRIN
                     VQLRPSLWGGVQAIVAIPEALLLQHEAEPAEATAELRLPASPAPQPSLLEVPSPPPGQA
                     AAGLPRRRGTSSSHAASQPPSDPVTPDATGREAHRPPLVRRSSVPRERVPQRPAPAPRG
                     TTAGSPAHDFMAQFTARETPSPTPSDH"
     gene            6024..6470
                     /locus_tag="CHF15_RS30725"
                     /old_locus_tag="SAMN05216252_12141"
     CDS             6024..6470
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015232.5"
                     /locus_tag="CHF15_RS30725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12141"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_179280040.1"
                     /transl_table=11
                     /translation="MDTTPKRSARNEAGGLLTDLMHRVPGTQRVLLATGDGLKIAWTDQ
                     DAAEADKLAALMTGLHSLARGAFVTAAGGVRQVAVEHDAGGLFVMSAEGDAANPRLVGT
                     LLGVVTTREASPGQVGFEMTRVIKGLGAQLAVQARDSQPAGRGQ"
     gene            6481..6846
                     /locus_tag="CHF15_RS30730"
                     /old_locus_tag="SAMN05216252_12142"
     CDS             6481..6846
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017170.5"
                     /locus_tag="CHF15_RS30730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12142"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_245939117.1"
                     /transl_table=11
                     /translation="MPSDAWAGSRLGDVRPYAVTAGRTQSRYDLSLTSSLCSRPATVGA
                     ALTPECEALLLHCSGHPRSIAELAARTGHPVQVTKILIGDLLDARAVTLNAPTPRNNPG
                     TDPQLLEAVLAGLKSLV"
     misc_feature    6511..6513
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6881..7441
                     /locus_tag="CHF15_RS30735"
                     /old_locus_tag="SAMN05216252_12143"
     CDS             6881..7441
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018549637.1"
                     /locus_tag="CHF15_RS30735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12143"
                     /product="GTP-binding protein"
                     /protein_id="WP_410169670.1"
                     /transl_table=11
                     /translation="MIAGGFGVGKTTFVGALSEIPPLVTEEVLTDVGQGTDSLDGISDK
                     TTTTVAMDFGRITFTHPQPMILFLFGTPGQQRFWFMWDDLCHGAIGAVVLVDTRHVEKS
                     FAAINYFEERHIPFVVAVNQFTDGDRYGADEVRDALEIAATVPVLICDARNRHSVLTVA
                     IALVTHALTAATPRPLTRHGAHA"
     gene            7438..7974
                     /locus_tag="CHF15_RS30740"
                     /old_locus_tag="SAMN05216252_12144"
     CDS             7438..7974
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018386207.1"
                     /locus_tag="CHF15_RS30740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12144"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_089227173.1"
                     /transl_table=11
                     /translation="MTHTEHQHASTEQRRTEVQRELGLTGDADPELDAFAARLAQEAGV
                     PFAMVNVFTPDRQQFVGLHAPDGPDAAPVGRTMPLHHGFCRAVVDRARPLVLPDVFAAP
                     RFAGDPVIDLLGIRTYAGAPLIHDGVVLGTVCAVGPDEKPQETGQDSLALVNRIRDEVM
                     AHLYRRAGHQQPHTP"
     gene            8121..9392
                     /locus_tag="CHF15_RS30745"
                     /old_locus_tag="SAMN05216252_12145"
     CDS             8121..9392
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542886.1"
                     /locus_tag="CHF15_RS30745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12145"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_089227174.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2e-28, bitscore:
                     92.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.8e-24, bitscore:
                     77.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.2e-27, bitscore:
                     89.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDWYLTPEHQRLRHEVRAFAETEIAPRVAAMEQSGAVEHDLAHA
                     IARQGWIAATIDTLHGGMGAGHLAKTIIIEELSRTSAAMGAMVQASQLGVAKVVHFGTQ
                     QQKRFWLPRFADGSCLPTIAVTEPVSGSHVLGMETTAVRDGDAYVLTGRKTYVGNSHIA
                     HVHGVVARTAPGSRGLTAFLVEANRPGLTLLPYRPTLGLRGFSFGELLFEQCRIPAGNR
                     LGDEGDGRDVAYSSSVLYGRPNLTAVSLGIHQAILDEVVRFSSDRLRYGKPLHHLTNIK
                     LKIGQITSRLMTARLAAYHAAHLLDTGVACDSDLMNAKLINAESAMDSARAAMEIEAAA
                     GLTTDRPLERYLRDAHHIYAPAGTSDIQLLRLAESALGLDKGQWSRRLAMPKSADQYAA
                     ASGLTEQQCPPGTARREVLNSSQP"
     misc_feature    9327..9329
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9607..9789
                     /locus_tag="CHF15_RS30750"
                     /old_locus_tag="SAMN05216252_12146"
     CDS             9607..9789
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010352623.1"
                     /locus_tag="CHF15_RS30750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12146"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_089227175.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.2e-14, bitscore:
                     47.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNNLGLGTTHVQPQTADSTTSDGFDLDITLLEVGDAAGLTNLTD
                     DGCGSTCGACTTGAA"
     gene            10001..12961
                     /locus_tag="CHF15_RS30755"
                     /old_locus_tag="SAMN05216252_12147"
     CDS             10001..12961
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543779.1"
                     /locus_tag="CHF15_RS30755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12147"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_089227176.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.1e-196,
                     bitscore: 648.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.3e-20,
                     bitscore: 66.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.7e-22, bitscore:
                     72.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLRTVCSDPDIAEALQHASPVLAARVDALLAASAPVFKEVRRV
                     VLSVSRYLLRAEHRATPFGLFAGVTTADLGSDPHVTWGAEPAVTARAGAGWISNVIERL
                     EACSELLERVPVVVNNTATIRGDRLVVPFLSEAAGNGDATRAVEASVSLTEPLHLVLSA
                     ARAPITVGELADKLATAFPSTGNAKVRRMISELVHRRVLITSLHAPSTHTDALGYLLEQ
                     LDALGADSLPSSAPLVSRLQAVAGGLRECATRPGREAVTAAMCSIAPGQASHPLAVDLA
                     FDAQIGLPASIAREVERTAWVLTRVSAHPFGTAQWSAYHMRFYERYGIGTMVPLQDVVA
                     DSGIGFPDGYPGASSGERRPRLSARDEVLVRLAQSAVLDGLEEVVLTDELVAALDVGPE
                     EVRVPPHLEIGVRVHATGVADLRRGRFRLEVASVSRGAGVSIGRFLDILRPGERAALYA
                     ELADLPAGDSKTVPAQVSFPPLLPQTAHVARAPKVLSTVISLQEHRVPGPEVLTPADLA
                     VGCDGRRMYVAAPGRGQRIEPVGLHALNLVRHTPPLARLLAELPRAQCAQVTLFDWGAA
                     AAMPFLPRVRYGRTVLAPARWRLEPSELPGRGRCRAEWDDQFAQWRVRRRLPQRVFLAE
                     GDQRLFLDLDQAGYRTLLRHHLDGARPAVLVEAPGPEAYGWCEGRAHEIVVPVKATRPP
                     AWPALPAPTWARAASPAQVQAPAGSSLLLISLYGDIRRQDAVLANHVPALLARLGDPAW
                     WFVRFRDPDQHLRLRIALPGPGAFAKTARTVSAWADELREAGLLSDLRFPTSYRELGRW
                     GSGPAWEAAEEVFRADSRAVLAQLRQYPRPHQRALVAAHFVAIASAFLGSTQAGMRWLI
                     GHVPPTAPGPVPREHFIDAVHLADPSGSWAALREIPGGAAILAAWADRDAALAAYRPHL
                     PGPDTQGIDVDDVLTSLLHVHFVRHVAVNFPEEEICLYLARAAALAFTARTSRSAR"
     aSDomain        10346..10627
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CHF15_RS30755_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="4.30E-21"
                     /identifier="RREFam001.1"
                     /label="CHF15_RS30755"
                     /locus_tag="CHF15_RS30755"
                     /protein_end="209"
                     /protein_start="115"
                     /score="66.4"
                     /tool="antismash"
                     /translation="VVVNNTATIRGDRLVVPFLSEAAGNGDATRAVEASVSLTEPLHLV
                     LSAARAPITVGELADKLATAFPSTGNAKVRRMISELVHRRVLITSLHAP"
     misc_feature    12398..12400
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12958..14232
                     /locus_tag="CHF15_RS30760"
                     /old_locus_tag="SAMN05216252_12148"
     CDS             12958..14232
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992138.1"
                     /locus_tag="CHF15_RS30760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12148"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_089227177.1"
                     /sec_met_domain="LANC_like (E-value: 9.4e-52, bitscore:
                     169.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEHPALALADAVATELTDPATAPLDKPAVTSHRQSLAHGLPGIA
                     LLHIERAAAGRGPWQHAHTWLTAAASTPLTSGPDSHPFYGAPALAHALACAAEHLPNAY
                     ASALDALDQQMRMDVARRLDTARRRLDAGDLPALAEFDAIRGLAGYGAYLLRRPGSEDA
                     LRAILEYCVHLTEPITHDGASLPGWWTPLGPSGRLDERFPGGHANNGMAHGVGGVLALL
                     ALAARRGHLVEGHHHALRTILAWLDQWQHNTGSGPSWPYWVTQEDMRTGELPHTGSQRL
                     SWCYGTAGIARAQQLAALTLGDTARQVVAEHALSVALHEPSQLRHTTDPGMCHGVAGLA
                     HIAARALQDAHASTRPQLLAVLPTLLDVVHSPQAHPTPAAQALLHNHRAGAGFLDGAAG
                     IALALLAPTTGSSPRTAWDACLLLG"
     gene            14259..16343
                     /gene="fxlM"
                     /locus_tag="CHF15_RS30765"
                     /old_locus_tag="SAMN05216252_12149"
     CDS             14259..16343
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960398.1"
                     /locus_tag="CHF15_RS30765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12149"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_089227178.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.3e-28, bitscore:
                     91.9, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 1.2e-46, bitscore: 152.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPTLWHQHNVVFPHRRTAQQVIAERIGPTLELAQEADQLTGWWF
                     MNKQPWPLRYRAAQPSELIETLLTSLVHDGTALAWHPAIYEPETDAFGGPHAMATAHQL
                     FHHDSRHLLAQHHRPALLGRRETAALLASSMMRAAGLDWYEQGDVWAKVAALRPTAPTL
                     APERATALTSAMRALMTTEPHRLCRPGRPLDGHSTWVDAFEEAGATLADLGRCGQLTRG
                     LRAVIAHHVIFHANRAGLPLDDQSALSHIAREAIMGSSDNTASTNKPTPTASSVDTVTT
                     DATTTPAADAEQLRNALVDQLQADGHARTPAVAAALRNVPRHLFVPDAPLEDAYANTPV
                     HIKYDTDGTSISCASQPEVVALMLDQLDVQPGQNILELGAGTGYNAALLAHLVGEHGHV
                     TTIDVDEDLVQGARAHLAAAGYSNVEALTRDGAVGHASGAPYDRIIATVGAHGVPHAWT
                     QQLARGGRLLTPQRLTGSVSRSIAYEHHEGRWISVDSAMNTFMPLRKGIADDDRQTVPL
                     AEDGTVRLQAPAGHEVDIAALAGVLAQPRTTQTWTGVLFRAMESPEWMELFVSCSVPSG
                     LFRMLFPPSAKGTLLTSDPYPSSTAAVEEGALTYLARRLSQQTTPDGGKLWEFGVIGHG
                     PGSEDLAAIVAEAIRTWDRLYRDRQATFEIQPLDAPADPPCSGHFTLATPLNRIAVAWH
                     "
     gene            16422..17522
                     /locus_tag="CHF15_RS30770"
                     /old_locus_tag="SAMN05216252_12150"
     CDS             16422..17522
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006347623.1"
                     /locus_tag="CHF15_RS30770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12150"
                     /product="hypothetical protein"
                     /protein_id="WP_179280053.1"
                     /transl_table=11
                     /translation="MDPRGAIAQRIPLIARFRPACLPLPERIQSLVELARSAADRVDQG
                     SASAVFNQAALLASDLDLPDLANRWCHQHAAAYLHACPLPGMSAIRALEPIVNLARLHI
                     RAGRANDGHTHLLSLYNAVCSGTACDFGTITVPAQLTRTEEDHNEVRAWLWRVLLADGT
                     RALTATGRWDEALTHVQAHRGVGSRMLDGRQVAVIAALTQRDTAQAARLIVETAPGEPW
                     EQQITLCLNVLRKRTDGKAKEADLEDLANSYTEDGPSGHGMTVFDIRHGLTILDLIENA
                     ENPHARRLAEDLYRRTMHALDGYAAREITSDPLFTTAATSPQIDSCHALIQRCGLNTRN
                     LNQPDHALVSRALTSSSNVIHRSLAP"
     gene            17951..18804
                     /locus_tag="CHF15_RS30775"
                     /pseudo=""
     CDS             17951..18804
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004993653.1"
                     /locus_tag="CHF15_RS30775"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MERRPYPSDLSDEQWALIEPMITAWKQGRVARSATGDPGSCDLRE
                     VVNAIFYQNRTGCQWRYLPHDLPTWSAVFYYFTLWRQDGLDQRVQELLRCQVRERARRL
                     EDPSLVIIDTQSVRAAAGVPKTTTGLDATGGCRAASGDWPSTFWG"
     misc_feature    17978..17980
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    18260..18262
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18801..19199
                     /locus_tag="CHF15_RS30780"
                     /old_locus_tag="SAMN05216252_12153"
     CDS             18801..19199
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007505818.1"
                     /locus_tag="CHF15_RS30780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12153"
                     /product="hypothetical protein"
                     /protein_id="WP_179280041.1"
                     /transl_table=11
                     /translation="MNVIELLADLQAQHDETTARAVELREQIKHLTTALAEIEARLADL
                     ATTRKVIAELAPAGGQPAPPETNTAYQAIVNAFNQHPDQEFRARELHELLGMPTDEASV
                     NITRSRLGRLTRQGFLTQPGRGRYQKRT"
     gene            complement(19222..19755)
                     /locus_tag="CHF15_RS30785"
                     /old_locus_tag="SAMN05216252_12154"
     CDS             complement(19222..19755)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579853.1"
                     /locus_tag="CHF15_RS30785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12154"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_245939118.1"
                     /transl_table=11
                     /translation="MSHDDEGQATLDEAVADAGLAAWEFDDARSWLEEALQRPMEPLAA
                     EVWVTDPRLEYVLLVKHRVRGWVPPGGKVEPGEGPRAAAARELFEETSLQAELLDQPAA
                     VAVRSYRADWSPTLGLSYAAIVGRDVPLRGEQGQQAAWFRLDAEWDSVFPDDRGRIRAH
                     VNRLAAGRAAGVTE"
     gene            20032..20277
                     /locus_tag="CHF15_RS30790"
                     /old_locus_tag="SAMN05216252_12155"
     CDS             20032..20277
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CHF15_RS30790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216252_12155"
                     /product="hypothetical protein"
                     /protein_id="WP_089227179.1"
                     /transl_table=11
                     /translation="MPAALLVEVYQHGEGAVEPLPWILIRAADVDPEQVWQLADAIATA
                     RHLPITVVLPATPATRQAFPHKREGDGHERHHVGRR"
     gene            complement(20695..21345)
                     /locus_tag="CHF15_RS30795"
                     /old_locus_tag="SAMN05216252_12156"
     CDS             complement(20695..21345)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432590.1"
                     /locus_tag="CHF15_RS30795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12156"
                     /product="nitroreductase family protein"
                     /protein_id="WP_089227180.1"
                     /sec_met_domain="PF00881 (E-value: 3.6e-22, bitscore: 72.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELDTLITKHLTRYFDPNKKIPEETIQLLLRYLRSSPTTVNIQPN
                     HFHVLESQAGKDKLADALVGRFADNAEKVRNASHAIVFTTRKTIPDKHLQEIFAKERAD
                     GRFADPEIQKGWEAGASNFVEIQSENYGGDVLHWLEKNTYLVVGATMMAAASLGVDATP
                     LEGFDRATIDEAFDLTDTDFTTTLLVMLGYPDETRVSRQPVSRFDAEKIFTHM"
     misc_feature    21349..21363
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.08"
                     /tool="antismash"
     gene            complement(21480..22013)
                     /locus_tag="CHF15_RS30800"
                     /old_locus_tag="SAMN05216252_12157"
     CDS             complement(21480..22013)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432588.1"
                     /locus_tag="CHF15_RS30800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12157"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_089227181.1"
                     /transl_table=11
                     /translation="MSRLTTPELTDIDAKTQGTLDTIAKQFGFAPGMFTTLAGNPAVLE
                     IVMSLQGSIAKLLDAKTRHTIALATSHSNNCAYCSALHGYISTNLAGMSTEEIELARTG
                     GSTDPKRAAVARFSQQVIETRGQVGDEDIAAVREAGYTDPEIQAIVTVVVVTLLTNYLN
                     NVNDTAVDIPGAGA"
     misc_feature    complement(22060..22080)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.45"
                     /tool="antismash"
     gene            22150..22794
                     /locus_tag="CHF15_RS30805"
                     /old_locus_tag="SAMN05216252_12158"
     CDS             22150..22794
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432587.1"
                     /locus_tag="CHF15_RS30805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12158"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_089227182.1"
                     /transl_table=11
                     /translation="MQMNDGSRDLRGRTGKGLATRGRILEHAADLIYTRGVHATNNELV
                     RRSAGISGSQLSHYFPNKESLVRAVIDWQAESVLGFHRSERFAGFETIEAYQEWADFYV
                     VSGRPFENGCSLGSLASEIVKTDLDVRDDLTRVFAEWQDIFRAGLERMQDAGRLDASAD
                     PAQLAHMLIAAYQGGSLLAQIARDVAPLRDALYAAVENLRAYTTSDDVART"
     gene            complement(22931..23602)
                     /locus_tag="CHF15_RS30810"
                     /old_locus_tag="SAMN05216252_12159"
     CDS             complement(22931..23602)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735727.1"
                     /locus_tag="CHF15_RS30810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12159"
                     /product="HSP18 transcriptional regulator"
                     /protein_id="WP_179280042.1"
                     /transl_table=11
                     /translation="MDATARPALRDADDDGPVPLMAAATALGAIDRALREARAADAGPA
                     PAGDTGQALASLMLLREVREQLASWERGLIETARAAGASWADLAGPLGVASRQAAERRY
                     LRLQPGAAGCTGEERVKATRDRRAADRLVTAWARDNAADLRRLAAHVTELTDLPPGARS
                     AIADIDAALARDDAARLMVPLEATRAHLLPGHPEVAARVDALTQRAEQLRQESDDQRRG
                     D"
     gene            23726..24160
                     /locus_tag="CHF15_RS30815"
                     /old_locus_tag="SAMN05216252_12160"
     CDS             23726..24160
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018561985.1"
                     /locus_tag="CHF15_RS30815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12160"
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="WP_089227183.1"
                     /transl_table=11
                     /translation="MLMRTDPFRELDRLTQQLLGTSGTWSRPQAMPMDAYREGDRYVIA
                     LDMPGVTPDAIDIDVERNMLTVKAERRPVAKADDVQMELSERPLGVFSRQLVLADTLDA
                     EHIEADYDAGVLTLRIPIAERAKPRKIAITSTGDRRQISG"
     gene            24265..24654
                     /locus_tag="CHF15_RS30820"
                     /old_locus_tag="SAMN05216252_12161"
     CDS             24265..24654
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018561984.1"
                     /locus_tag="CHF15_RS30820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12161"
                     /product="DUF2267 domain-containing protein"
                     /protein_id="WP_179280054.1"
                     /transl_table=11
                     /translation="MRPEVFLAQVQERGEYSTPQEADRAARVVLGLLGAHVVGKERAEL
                     AARLPETYALILLNPLQAVEPLDAERFVRATAAWIEGASEQTARWDVGAVLSVAADEAG
                     PDLLRRLLLQLPPGYDLLFGHLEPA"
     misc_feature    complement(24699..24713)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.76"
                     /tool="antismash"
     gene            24724..25158
                     /locus_tag="CHF15_RS30825"
                     /old_locus_tag="SAMN05216252_12162"
     CDS             24724..25158
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018835264.1"
                     /locus_tag="CHF15_RS30825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_12162"
                     /product="DUF2267 domain-containing protein"
                     /protein_id="WP_089227185.1"
                     /transl_table=11
                     /translation="MYAQRQAAAPVSAMTFEAMVEQVRYDGAYPTHDRAEQAVRHVMAG
                     LGRQLIGDERVALAARLPLEAALELTAQVPRTEPLTGFDFVSDLAARTGGTPATARWDA
                     GIVFAVLRRLTGDDLISSVLAQLPSGYALLFGRAELAPTG"
ORIGIN
        1 gaaggtcaat gggcggagtg ggcagcgtgt gtagcgcata tagaggcttt gccaactggg
       61 ctgcagcgac aggatgattg ggttggggga gatacgtcca gaaggtgatg gcgtgttgat
      121 cgacaacgac aggttgatcg actgggtgca ggggggccgt gggaaatccg gcctcggtaa
      181 gccagcggac aaatctgaca gtgcgtgtga cgtggtcgat gggcgagccc ttccgtgcga
      241 tcttgactac gacgttctct gcgttgaggt ggacaactgc attggtgtgt ccgcgcaaga
      301 ggcgagcgtc tgcagtgttg aggccaacga tcgagcagcc tcggtccagc acgcgccgca
      361 tctcagcctc gtcaaacccg ccgggcgccg gcgtcgtgtc tgtcatgaca cccaggctcg
      421 ccgactttcc gcgtcgctgt cacacctgtc cgggaggaag cgccaagatg tcacgaagct
      481 cacgtaccgc gcgcccgtcc cgtatgcctg gaggcaaggc ctggatcacc tcgtgagcgc
      541 gctgctccac gataggcgtg cgatgcgcag gagtgattcg caggatcgcg gttcctgcga
      601 cctgacaggc ctcggctgcg ctgcgctctc gggccaggca gatggccgtt tccaagctga
      661 ggagcgctgg gtcgatgccg gttctggctg gatagaggcg tagtgccgcg tcttgagtac
      721 gtcgggctcg gctggtgtgg cccagggagg tgagtgttcc gctttcgtag agaaggaagc
      781 gtctctcggg gaagccgaag gcgtcgttgt cggtcggccc gcctgctccg ctttgttcga
      841 atgcggaagc tgcgtggcgt agtgctacgt ccgcgccgag agcgtcgccc attttcgcca
      901 gggcccgggc ttcggccgcg gcggcgaacg ccgcggtggc ggagggtctg ccccggcaga
      961 tgatccgtgc ttcccgtgcc aggttcacgg cggcttcgag ggggccgtag tagaagggga
     1021 gcattgcggc ctgtgccctg acccgtgccc gcagttctgc gttgccgctg tcatcggcgg
     1081 cattgcgggc cgtcgcgtac caggactgcg atctggaaag ctgtccgagc ttcataagcg
     1141 catcggcgac caaggtggca agcatggcca ccaactccga gagtcggact tgcaccgctg
     1201 ccggctgccg gtgggcggag agctcgtcga cctctgccag gtgccggagc aaggtttcga
     1261 tcatgggtgc tggcggagtg taaacgtact gctcgcgggc ccagagcacc tgctcgtcca
     1321 acaagtcgag ctgagtcgcg ctgacggttc cggctgtaag ggtacggtcc acggaccacc
     1381 tggctgcgtc gacctgctgt gcaagggtgt cggtgtcggt gaagcctttc tggggtgagc
     1441 gcggaatcag ggcctgtatg gcgggcacgt tggtgggcga catggcgctg cgtgcgaacc
     1501 cgatgtccgc cacggtgcag tcgaagaact cgcagagcag ttcgatggtg ttgttgcgcg
     1561 gtcggcggcc tgactcccag tgtcccagtt gatcgccgtc ggtccgcgga gcgtcggcgc
     1621 ggccttctgc gatgcggttg agatcgtcgg cggtctgctt caaggtgagg ccacgtgcga
     1681 ggcgctgtgc gcgaagttcg gacaccccgc agtgcacatg gatgattcga gcgatttgct
     1741 ggttcgaagc tccccgctgg ctggctgcct gccggagctg ctttgcgcag gatggtgggt
     1801 gcgccgcctg gggcatcagc cctccttcgc tcggtggtcg cgttagaaag agcgtagtga
     1861 cgggccgtca taggcgctgc caatcagtca gtcatttccc gcgccggacg agaatcagtg
     1921 acttctttcc ttcgcagtaa ctgatcagtg actgatgcgg cttgcctgcc tggtcgcctt
     1981 gggagcacct ttctggtctc gcaacgcaga gcttctcctc ggacgacccc gcctccagtc
     2041 agcggaggca ccgtccctcg gcataggaac gcggcttgtc cccaggtcag gccataaccc
     2101 aggaggtgta cagcatgacg gcgccgacca gcagacagtt cctgacagcg ctggcgtccg
     2161 gggagggagt cgatcgcgtc tcggttcacc tggaaagcac ggcaagttcc gtcggcaagg
     2221 cgcgccgctt cgtcgaaagg cagctcgtct cttgggggtt tccgccagac gaggacgtag
     2281 tgcagcgggt cgtgctcacg gtcagcgaac tggccaccaa tgccgtgctc cacggtaggt
     2341 cgcgaccgcc ggccgaggat gaactgatcg aagtagccct ctcgctcaag ccggacttcg
     2401 cgctgggagt cgcggtcacc gacgactccg atgcactgcc cctgactccg acaagcactt
     2461 cagcgacggc aacgcgcggg cgagggctcg ttctcgtcag tgccctcgcg gacagctgga
     2521 tgaccgcgcc ccgccagcgc caggaagccc atcaaggcaa ggacgtatgg gcgttcttcc
     2581 gttgccacga aaccagcgtc gcgcttccgc ggacagcgtg accacggtag cgacctcccc
     2641 ctctatggac agccgatcgt tctggacccc agcggtcgaa agcgagccca tgatcacacc
     2701 gcctcggagt tctcttctgt ggttcccgcc aatccccccg cggcgtgcgc acgagggtgc
     2761 cggaccgcga cacatgacgt tcccgtcact cggctctgcg atgactggtg tccggcgtca
     2821 tcgtcagcca acggccatgt cgtcctatgg acccggagcg gtgtcatgag gccgacgacc
     2881 ttcctcagca atgggctgcg tgtcccgtat gtggttgcgt ggacagccga gacaccgcag
     2941 gtggcaccgg tgagaattcg tccgggaccc aacggagcgc gtcttgggta cgtgcacgag
     3001 gatcccgtgg ccgacctgta cgagaacgtg ctgtgggtcc ggcagccgat cgcaccaggc
     3061 cgcgggcggc cccacttcgc tggcatccac tcgcggcgcc agcgccgatg cctgcagtac
     3121 atgctgtgcc aggtctgtga tgtgactacc ttcgcaaggg cagacggccg tcacctgttt
     3181 ctgttgcggg cgaatggcga gcagccgatc gcagagggcg agaggaccac cgcaggaccg
     3241 gtgtgtgtgc cgtgcgcagt gcagtccgtg gccttctgcc cgcacctgcg aggctcctat
     3301 acagcagcgc tcgtcagcta ctgcccgacg tggggagtcg caggtgtggt ctacgacccc
     3361 gacaccctgc acccgctctc cgcagggcct gacaaccctc tggaactcgt ggctcatgac
     3421 gacccgcgga tctcgtggac gctggccgcg cgatacgtcg tgagcctgca cggctgcgaa
     3481 ccagtcaacg ttgcggatct cgagaaggcc gaagccgaca cgcttcaccc cccggccagc
     3541 ggctcggcgc caggggcgac ggtcatgaag ggcatccatc cggtccatcg tgaccagcct
     3601 cccgctctgc tgcccgaggg cctgccgaga cgccttcccc ctagaccgct gcccgcccca
     3661 ccgggcagct aggacgcgtc gccgaccgcg tccgactcgt cacggctccg tttccccctg
     3721 acggatccgg gacgtggcaa taccccgtgc cgacgtcgcg accccatcgt gcgcgtcgtc
     3781 ggcacggggg caccccagtc ccgcctagga gatgcctgcc ttgaacgcga agcacctgag
     3841 gattcttcgc atcgtggtgt tcgcgctcgc gatcgtgatg atcttcctgg ccacgtggct
     3901 gccgcaccac tgagagaacc caatttctgc ccaccttgga cggccgtgtt cgtcccgacc
     3961 ggagtttcga tgccatcccc ttccagcacg atccagccct ggcaactcgc gctgtccgag
     4021 tggccacgtc cggcagggct gcccgcacag cacgacatcg tggccaccgc gatgggcgtc
     4081 ggcctgccgg ccgttgaggc attacgtctc cagccggcca cggtgggacc catcctgtgc
     4141 tgcccgctgc acaggttctt gctgatcccc gtgcccgcgg ggaccgcgga ggtgtggcag
     4201 gcgccgcact cgcggtgctt gccgggtggg cgctgggact gcgccgaact cctggggtcc
     4261 ggcccggctc gctgcggcag ccgcttctgg cttttcgacg gcgtccaggc cccggctgcg
     4321 gtcaccaacg cccgcgacct gtacgacagc ctgagtcgga cccgttcgcg cttgcggacg
     4381 ggcgtccacc ggtgctcggg tcacatggtt cgcgaggtgt ccggtgtctg atcacgtctc
     4441 tcgcacgggc gcagcgtctg gtcggcggcg ccgagcacac agcgcggggt ccccgggtgt
     4501 cgctgccgcg ccaggggtga tggtcgctgc tttgacgagc gccgcggttg gtggcgggtg
     4561 gctggcggac agtctcagca tcgtcccagc gtcggcagca gcggcggctt cgggttcgct
     4621 ggtcctggcc gtgggtgtct gggcgggtgt gcgccgcatc gatgcccgga ggcggactgc
     4681 cgcccagata ggccagctca ggcatgagag ggaccggctg cagcaggccc tgcgcgacgt
     4741 ctctgacgcg gtcgccgtgg gcaggaagcg ggtcgcctgg gctgtggatc aggcctccca
     4801 gggacagttc gccagaggcg agtcggcgat tgcgccggtg gagtctgggg acctgtgcac
     4861 ggatgtcctg gcgagtctgc agtgtgcgct ggccgagggt tggcaggcgg tgttgcgggc
     4921 tgccgaacag cagcacgagg cgttggcagc cgaggcggag ctggctgatc ttgcacgctc
     4981 catcaccccg cgcatgcaga gcctggtcaa ccgcggcatt gctctgatcg aacgggtcga
     5041 gcgcagtgtg gaggacccgg accttcttca cgaactgttc caggtcgatc atctgctcac
     5101 tcagatgcgc cgggccgggg aaagcctcgc ggtcctgggc ggcagtactc cccctgagca
     5161 tgcgcagccg ctcctggtcg caaccgcgct gcggcgggcg gtggccgaga tcgagcacta
     5221 cccccgtgtc cggatcgcgc agcagcttca gccaagccgg ccgttcgccc tgccgggcta
     5281 cgtgagccca agtgtggtgc acctgctggc cgagatcatg gacaacgccg cacgctattc
     5341 caccgacaag gtggaggtgt acaccaccga ggtacgcggc gggctgctca ttgaggtcct
     5401 ggaccgcggc ggcggcatac cggatgacaa gcgcgccgtg ctcaatgacc tgctggccag
     5461 accggaagca gtagagcggc gcgccagggt caaggatggg cagatcgggc tgctcgtggc
     5521 cgctctgctg gcccggcggt accgcatcaa tgtccaactg cggcccagtc tttggggtgg
     5581 cgtccaggcg atcgtcgcca tccccgaagc cctgctgctg cagcatgagg cggagccggc
     5641 agaagccacc gcagagctgc gccttccggc ctcgccggct ccccagccgt ccttgctcga
     5701 ggtcccctct ccccctcccg ggcaggctgc agcagggctt cctcgccggc gtggtacctc
     5761 gtcttcgcat gccgcctcgc agcccccttc cgaccctgtg accccagatg cgacggggcg
     5821 cgaggcgcac cgtccaccgc tggtccggcg aagctccgtc ccgcgggaac gggtgcccca
     5881 gcgtccggca cctgctcctc gagggaccac cgctggttct cccgcacacg acttcatggc
     5941 gcagttcact gcgcgcgaga cccccagccc gacgccgagc gaccactgac tctccatccc
     6001 cacgacctgg caggagactt tcgatggaca ccaccccgaa gcgttcggct cgcaatgagg
     6061 cgggcgggct gctgacggac ctgatgcacc gggttccggg tacgcagcgt gtgctgctgg
     6121 ccaccggtga cggcctcaag atcgcgtgga ccgaccagga cgcggcggag gcggacaagc
     6181 tggccgcgct gatgacgggt ctccactcgc tggcgcgcgg cgccttcgtc accgctgcgg
     6241 gaggggtgcg acaggtcgcg gtggagcatg acgccggggg cctgttcgtg atgagcgcgg
     6301 aaggcgacgc cgcgaacccc cgcctggtcg ggacactgct gggcgtcgtc accacccggg
     6361 aggcatcccc ggggcaggtg ggtttcgaga tgaccagggt gatcaagggc ctgggggccc
     6421 agctggcggt gcaggcccga gacagccagc cggccgggcg ggggcagtga catgcctgcg
     6481 gtgcccagcg acgcgtgggc cggcagccgc ttaggcgacg tccgccccta tgccgtcacc
     6541 gccggccgca cccagtcgcg gtatgacctc agcctgacct cctcgctctg cagcaggccg
     6601 gccactgtgg gcgcggcgct caccccggag tgtgaggccc tgctgctgca ctgcagtggc
     6661 cacccccgct cgatcgccga gcttgccgct cgaacaggcc acccggtgca ggtaaccaag
     6721 atcctcatcg gcgatctcct cgacgcccgc gctgtgaccc tcaacgcccc cacgccccgc
     6781 aacaacccgg gcaccgaccc gcagctcctg gaggccgtcc ttgccggact caagtccctc
     6841 gtctgaccgc ctgccgaccg cgcctgacga ggtgaagatc gtgatcgccg ggggtttcgg
     6901 cgtcggcaag accaccttcg tcggcgcact cagcgagatc cccccgctcg tcaccgaaga
     6961 agtcctcacc gacgtcggcc agggcaccga cagcctggac ggcatcagcg acaagacgac
     7021 caccacggtg gccatggact tcgggcggat caccttcacc cacccccagc cgatgatctt
     7081 gttcctgttc gggacccccg gccagcagcg cttctggttc atgtgggacg acctatgcca
     7141 cggtgccatc ggcgccgtgg tcctggtcga cacccgccac gtggagaaat ccttcgccgc
     7201 catcaactac ttcgaggagc gccacatccc cttcgtcgtc gccgtcaacc agttcaccga
     7261 cggcgaccgg tacggcgccg acgaggtccg cgacgcactg gaaatcgccg caaccgtgcc
     7321 cgtcctcatc tgcgacgccc gcaaccgcca ctcggtcctc accgtggcca tcgccctggt
     7381 cacccacgcc ctcactgccg ccactccccg tcccctcacc cgccacggag cacacgcatg
     7441 acccacaccg agcaccagca cgccagcaca gaacaacgcc gcaccgaagt acagcgggaa
     7501 ctcggcctca ccggagacgc cgatcccgaa ctcgacgcat tcgcagcccg cctggcccaa
     7561 gaggcgggcg tgcccttcgc catggtcaac gtcttcaccc cggaccggca gcagttcgtc
     7621 ggcctacacg cccccgacgg ccccgacgcc gcaccggtgg gccgcaccat gcccctccac
     7681 cacggcttct gccgtgccgt ggtcgaccgg gcccggccac tggttctgcc ggacgtcttc
     7741 gccgccccgc gcttcgccgg cgaccccgtg atcgacctgc tcggaatccg cacctacgcc
     7801 ggtgcacccc tgatccacga cggcgtcgtg ctcggcaccg tgtgcgcggt cggccccgac
     7861 gagaagcccc aggaaaccgg ccaggactca ctggccctgg tcaaccggat ccgcgacgag
     7921 gtcatggccc acctctaccg gcgggccgga caccagcagc cgcacacccc ctagccctgc
     7981 ctcctgcgat ctcatccgtc accgcgcgct gctgtcgccg agacgcggcg ccggcgatgg
     8041 cagcggccta cccatccggc gcccacgtgc tgtcgaacgc cacgaccgat gcccccacag
     8101 cagtgaaggg agcccccacg atgtccgact ggtacctgac accggaacac cagcggctgc
     8161 gccacgaagt ccgagccttc gccgagaccg agatcgcacc ccgtgttgcc gccatggaac
     8221 agtccggggc tgtcgagcac gacctcgctc acgccatcgc acgtcaggga tggatcgctg
     8281 ccaccatcga caccctccac ggcggcatgg gcgccggcca cctcgccaaa acgatcatca
     8341 tcgaagagct ctcccgcacc agtgccgcca tgggcgccat ggtccaggcc tcccagctcg
     8401 gcgtcgccaa agtcgttcac ttcggcaccc agcagcagaa acggttttgg ctgccccggt
     8461 tcgccgacgg ctcctgcctg cccaccatcg cggtcaccga acccgtctcc ggcagccacg
     8521 tcctgggcat ggaaaccacc gcagtccgcg acggcgacgc ttacgtcctc accggccgca
     8581 agacctacgt cggcaactcc cacatcgccc acgtgcacgg cgtcgtcgcc cgcaccgcac
     8641 ccggatcacg cggactgacc gcattcctcg tcgaagccaa ccggcccggc ctgaccctgc
     8701 tcccctaccg gcccacgctc gggctgcgcg gcttcagctt cggcgaactc ctcttcgagc
     8761 agtgccgcat ccctgcgggc aaccgtctcg gagacgaggg cgacggccgg gacgtcgcct
     8821 actcctccag cgtcctgtac ggccgcccga acctgaccgc cgtctccctc ggcatccacc
     8881 aggccatcct cgacgaggtc gtccgcttct cctccgaccg ccttcgctac ggcaaacccc
     8941 tccaccacct gaccaacatc aaactgaaga tcggtcagat cacctcgcga ctgatgaccg
     9001 cacgtctcgc cgcctaccac gcagcccacc tcctggacac cggcgtggcc tgcgacagcg
     9061 acctcatgaa cgccaaactc atcaacgccg aatccgccat ggactccgca cgcgcagcca
     9121 tggaaatcga ggcagccgcc ggactgacca cggaccggcc cctggagcgc tacctccgcg
     9181 acgcccacca catctacgcc cccgccggca cctccgacat acagctcctc agactcgccg
     9241 aatcggcgct cggcctggac aagggccagt ggtccaggcg actggccatg cccaagtcgg
     9301 cagatcagta cgccgccgcg tccggcttaa ccgagcagca gtgcccgccg ggcactgccc
     9361 gacgcgaagt cctcaacagt tctcagccgt gaagcggtca tgcggtccgt gcatcgatcc
     9421 cgggacgtgt tcggctcgta gacggcgtga ttcaactgcc cgcagagact tcccggttcc
     9481 tacggccttc gtcgacgggg accgggagac cgggcctgac ccagcgcggc aacccgctgt
     9541 gctgccaagg cctggcgaga tcggtacgac ccatccagat caacccaacg attcacagga
     9601 gttgccatgc ccaacaacct cggcctcggc accacccacg tacagccgca gacagcggac
     9661 tcgaccacgt cggacggctt cgacctggac atcaccctgc tcgaggtcgg cgacgcggcc
     9721 ggtctgacca acctgaccga cgacggctgc ggctcgacct gcggtgcctg caccaccggt
     9781 gccgcctgac aacgacacct gtcccttgtc cggtgccgcc acgcccaggc gtggcggcac
     9841 cgctgcccgc tcccgtcaat tggaggacac tgtggcttct tccccttcag cgttccgggc
     9901 tggaacgact gcactggtgc gtgcggtggc ctacccagcc cgtcggtatc cgccgcttcc
     9961 cgatctcgac gaacgctcct ccccaggcac ctcggcctcc ttgacctggt tgcggacggt
    10021 ctgctcggat cccgacatcg ccgaagcgct gcagcatgca agcccggtcc ttgccgcgcg
    10081 agtcgatgcg ctccttgccg cgagtgcacc agttttcaaa gaggtgcggc gcgtggtgct
    10141 gtcggtgagc cgctacctgc tgcgggccga gcacagggcg actccattcg ggttgttcgc
    10201 cggcgtaacc accgccgacc tcggatccga ccctcacgtg acatggggcg ctgagccggc
    10261 agttaccgct cgggccgggg ccggatggat aagcaatgtg atcgagcgct tggaggcgtg
    10321 ttccgagctg ctggaacgcg tgcccgtcgt ggtcaacaac accgccacca tccgcggaga
    10381 caggctggtg gtgccgttcc tgtcggaagc tgcgggaaac ggcgacgcca cgcgtgccgt
    10441 cgaagcctct gtgtccttga ccgaaccact gcacctggtg ctgtccgctg cccgcgcacc
    10501 catcactgtc ggcgaactcg ccgacaagct tgccactgca ttcccctcca ccgggaacgc
    10561 gaaggtccgg cgcatgatca gtgaactggt ccaccgtcgt gtcctgatca cgagcctgca
    10621 cgcacccagc acgcacaccg atgccctcgg gtacttgctc gaacagctcg acgccctggg
    10681 cgccgacagc ctcccctcca gtgccccgct cgtttcccgg ctgcaggccg tcgctggggg
    10741 cctgcgggag tgcgccaccc gtcctggccg ggaggcggtg actgctgcca tgtgctcgat
    10801 agctccggga caggcgtccc atccgttggc ggtggatctg gccttcgacg cacagatcgg
    10861 tttgccggca tcgatcgctc gcgaagtcga acgcaccgcc tgggtgctga cgcgtgtgag
    10921 cgcgcaccca ttcggtacgg cgcagtggag tgcgtatcac atgcggttct acgagcggta
    10981 cggcatcggc acgatggtgc cgttgcagga cgtcgtggcg gacagcggca tcgggtttcc
    11041 cgacggctat cccggcgctt cgtccggcga acggcggccg cgtctttccg cccgggacga
    11101 ggtcttggtg cggttggcgc agtcggctgt gctcgatggg ctcgaggagg tggtccttac
    11161 cgacgagctg gtggcagcgc tggacgtggg gcccgaggag gtccgggtcc cgccgcatct
    11221 ggagatcggc gtgcgtgtgc acgccaccgg tgtcgccgat cttcggcgcg gccggttccg
    11281 gctggaggtt gccagcgtgt cccgtggcgc cggcgtttcc atcggccggt tcctggacat
    11341 cctgcgtccg ggcgagcggg cagctttgta tgccgagttg gctgaccttc cggccggtga
    11401 cagcaaaacg gtgccggcgc aagtctcctt tcccccgctg ctaccgcaga ccgcacacgt
    11461 cgccagggct ccgaaggtcc tgtcgacggt gatcagtttg caggagcacc gtgtacctgg
    11521 ccccgaggtg ctgactcctg cggacttggc ggtgggctgc gatggccgcc ggatgtatgt
    11581 cgctgccccc ggacgggggc agcgcatcga gccggtgggc ctgcacgcgc tcaatttggt
    11641 gcgccacacc ccacctctgg cacggttgtt ggcggagttg ccccgcgccc agtgcgctca
    11701 ggtcacgctg ttcgactggg gcgctgcggc ggcgatgccg ttcctgcctc gggtgcggta
    11761 cggccggacg gtgctggctc cggcccgctg gcggctggag ccatccgagc tgcctggccg
    11821 cgggcgttgt cgagccgaat gggacgacca gttcgcgcag tggcgggtgc ggcggcgcct
    11881 cccgcagcgg gtgttcctcg ccgagggcga ccagcgcctg ttccttgatc ttgaccaagc
    11941 gggctaccgg acactgctgc ggcaccatct ggacggtgcc cgtccggcgg ttctcgtcga
    12001 agcgcccggc cctgaagcgt atggctggtg cgaaggtcgc gcccacgaga ttgtggtccc
    12061 ggtcaaggcg acccgtccgc cggcctggcc ggctctgccc gccccgacct gggcccgcgc
    12121 ggcttctccc gcccaggtac aggcccccgc cggctcgtcg ctgctgctca tctccctgta
    12181 tggggacatc cgccgccagg acgccgtact agccaaccat gtgcctgcgc tgcttgcgcg
    12241 gctcggggac ccagcgtggt ggttcgttcg cttccgtgac cccgatcagc acctgcgcct
    12301 gcggatcgcc ctgcccggcc caggcgcctt cgcgaagacc gctcgcacgg tgagcgcctg
    12361 ggcagatgaa ctgcgcgagg ctggattgct gtccgactta cggttcccca cctcctaccg
    12421 tgaattgggc cgctggggct ccggaccggc ttgggaagcg gccgaggagg tgttccgtgc
    12481 ggattcgcgg gctgtcctgg cccaactccg ccagtatccg cgcccgcacc agcgggcact
    12541 ggtggccgca cacttcgtcg cgatcgcttc cgcgttccta ggcagtaccc aggccggtat
    12601 gcgctggctg atcggccatg tccctcccac tgcgcccgga cccgtgcctc gcgagcattt
    12661 catcgacgca gtgcacttgg ctgacccgtc cggcagctgg gcagccctgc gtgaaatacc
    12721 cggcggagcc gccatccttg cggcgtgggc cgacagggac gccgcgttgg cggcctaccg
    12781 gccgcacctg cccggccccg acacccaggg catcgacgtc gacgacgtcc tgacatccct
    12841 gctgcacgtc cacttcgtgc gacacgtggc agtcaacttc cctgaagagg agatctgtct
    12901 ctacctcgcg cgcgccgcag cgctggcctt cactgcccgc accagcagga gtgcccgatg
    12961 accgagcatc ccgcactcgc cctggccgac gccgttgcca ccgaactcac cgaccctgca
    13021 acagcgccgc tggacaagcc ggccgtgaca tcgcaccggc agtccctcgc ccacggtctc
    13081 cccggcatcg ctttgctgca catcgaacgc gccgcagcag gacgaggccc gtggcagcac
    13141 gcccacacct ggcttactgc ggccgccagc actcccctga ccagcgggcc ggacagccac
    13201 cccttctacg gtgcgcccgc ccttgcccac gccctcgcct gtgctgctga gcacctgccg
    13261 aatgcctacg cgagcgccct tgacgcgctg gatcagcaga tgcgcatgga tgtagcccgc
    13321 cgcttggaca ccgcgcgtcg ccgcctcgac gcaggggacc ttccggccct cgccgagttc
    13381 gacgcgatcc ggggcctggc cggctacggc gcctacctcc tgcgccgacc aggcagcgag
    13441 gacgccctgc gcgccatcct ggagtactgc gtgcacctga ccgaaccgat cactcacgac
    13501 ggagcgagcc ttcccggctg gtggactccc cttggaccat ccggccggct ggacgaacgg
    13561 ttccccggcg ggcacgccaa caacggcatg gcacacggag tcggcggcgt cctcgccctg
    13621 ctcgccctcg ccgcccggcg cggccacctc gtagaaggcc accaccatgc gctacgcacg
    13681 atcctggcat ggctggacca atggcaacac aacaccggca gcggcccatc ctggccgtac
    13741 tgggtcaccc aggaagacat gcgcaccggc gagctccccc acaccgggtc acagcgactg
    13801 tcgtggtgct acggcaccgc aggtattgcc cgcgcgcagc agcttgccgc gctcacgctc
    13861 ggcgacaccg cccgccaagt cgtagccgaa catgccctgt cagtggccct gcacgaaccg
    13921 tcgcagcttc ggcacacgac ggacccgggc atgtgtcacg gcgtcgcggg cctggcacac
    13981 attgcggccc gtgccctcca agacgcccat gcatcgacgc gcccgcaact gctcgcggtc
    14041 ctgcccacgc tcctggacgt agtccactcg ccgcaggccc accccacacc agcagcacaa
    14101 gcactgctgc acaaccaccg tgccggggcg ggattcctcg atggtgccgc cggcatcgcc
    14161 ttggcccttc tcgcccccac caccggctcg tcaccccgaa ctgcctggga cgcctgcctg
    14221 ctcctgggct agccctgccg accgcgtaaa ggaatcctgt gtcccccacc ctctggcacc
    14281 agcacaacgt cgtcttccct caccgcagaa ccgcccagca agtcattgcc gagcgcatcg
    14341 gcccgaccct ggagctggcc caagaagccg accagctcac cggctggtgg ttcatgaaca
    14401 aacagccctg gccactgcgc taccgtgccg cgcagccctc cgaactgatc gagaccctgc
    14461 tcaccagcct cgtccacgac ggcacggcac ttgcgtggca cccagccatc tacgaacccg
    14521 aaaccgacgc gttcggcggc ccacacgcca tggccaccgc ccaccagctc ttccaccacg
    14581 acagccgcca ccttctcgcc caacaccaca ggccagcact cctcggccgc cgggagaccg
    14641 ctgcactgct ggccagttcc atgatgcgcg cggcaggact ggactggtac gagcaaggag
    14701 acgtgtgggc caaggtcgcc gctctgcgac ccaccgcccc caccctggcc cctgagcgcg
    14761 cgaccgcact gacatcggcg atgcgcgcct tgatgaccac cgagccccat cgcctgtgcc
    14821 ggcccggccg accgctcgac ggacacagca catgggtgga cgccttcgaa gaagccgggg
    14881 ccaccctcgc cgacctcggt cgttgcggtc aactcacgcg aggcctacgt gccgtcatcg
    14941 cccaccacgt gatcttccac gccaaccgcg ccggtctccc cctggacgac caaagcgccc
    15001 tgtcccacat cgcacgagag gccatcatgg gatccagtga caacaccgcg tcaaccaaca
    15061 agcccacacc caccgccagt agcgtcgaca cggtgaccac cgacgccacc accacgccag
    15121 cagccgacgc cgaacagctc cgcaacgcac tggtcgacca gctccaagcc gacggccacg
    15181 cccgcacccc agccgtcgca gccgccctgc ggaacgttcc ccgccatctg ttcgtacccg
    15241 acgccccact cgaagacgcc tacgccaaca cgccggtaca catcaagtac gacaccgacg
    15301 gcacctcgat ctcctgcgcc tcccagcccg aagtcgtcgc cctgatgctg gaccaactcg
    15361 acgtccaacc cggccagaac atcctcgagc tcggcgcagg gaccggctac aacgccgcgt
    15421 tgctggccca tctcgtgggc gagcacgggc acgtcaccac catcgacgtc gacgaagacc
    15481 tcgtccaagg cgcccgggcg cacctggctg cggccggcta cagcaacgtc gaagccctca
    15541 cccgcgacgg cgctgtcggt cacgcttccg gcgccccgta cgaccggatc atcgcgaccg
    15601 tcggcgccca cggcgtaccc cacgcctgga cgcagcagct cgcacgcggc ggccggcttc
    15661 tgaccccgca gcggctgacg ggcagcgtct cacgctccat cgcctacgaa caccacgaag
    15721 ggcggtggat ctccgtcgac agcgcgatga acaccttcat gccgctacgc aagggcatcg
    15781 ccgacgacga ccgccagacc gtccccctcg ccgaagacgg caccgtgcgg ctccaggccc
    15841 cggcaggaca cgaggtcgac atcgcagcac tggccggtgt ccttgcccag ccacgcacca
    15901 cacagacctg gaccggagtg ttgttccggg ccatggagag ccccgagtgg atggaactat
    15961 tcgtgtcctg ctccgtgccc tccggtctgt tccggatgct gttccctcca tccgcaaagg
    16021 gcaccctcct caccagcgac ccctacccgt cctccaccgc ggccgtcgag gagggagccc
    16081 tcacctatct cgcccggcgc ctgtcgcagc agaccacccc ggacggcggc aagctgtggg
    16141 agttcggagt catcgggcac ggccccggaa gcgaggacct cgccgccatc gtcgccgaag
    16201 ccatccgcac ctgggaccgc ctctatcgcg accggcaagc caccttcgag atccagcccc
    16261 tcgatgcacc cgctgaccca ccatgctccg gccacttcac acttgctact ccgctaaacc
    16321 gcatcgccgt cgcctggcat tgagccttcc ccgggtgcct gccgaccctg cggtcggcgg
    16381 gcaccctgcc ccactccccg attcaaggga cgcccatgga cctggatccg cgcggcgcca
    16441 tagcccagcg catcccattg atcgcacgtt tccgccccgc ctgccttccg ctgcccgaac
    16501 gcatccagtc gctcgtcgaa ctcgcccgct ccgcggcaga ccgggttgac cagggcagtg
    16561 cttcggctgt cttcaatcaa gccgcactcc tcgcctccga cctcgatctc ccggacctgg
    16621 ccaacaggtg gtgtcaccag cacgccgccg cctacctcca tgcctgcccc ctgcccggca
    16681 tgagcgcgat ccgcgcgctc gagccgatcg tcaaccttgc ccgcctccac atccgcgccg
    16741 gccgcgccaa tgacggtcac acgcacctgc tctccctcta caacgccgtc tgctccggca
    16801 ctgcctgcga cttcggcacc atcacggtgc cagcccaact caccaggaca gaagaagacc
    16861 acaacgaagt ccgcgcctgg ctgtggcgcg tcctgctcgc cgacggcacc cgcgccctca
    16921 ccgccacagg ccgctgggac gaagccctca cccacgtcca ggcacaccgc ggtgtcggta
    16981 gccgcatgct cgacggccga caggtagcgg tgatcgccgc tctcacccag cgggacaccg
    17041 cacaggccgc caggctcatc gtcgaaacag cccccggcga accctgggaa cagcagatca
    17101 ctctctgtct gaacgtccta cgtaagcgca cggacggcaa agccaaagag gcagacctgg
    17161 aagatttggc gaactcctac accgaagacg gcccctcagg ccacggcatg accgtcttcg
    17221 acatccgtca cggcctgacc atcctggacc tcatcgaaaa cgccgaaaac ccccacgccc
    17281 gacgcctggc cgaagatcta taccgacgca ccatgcacgc cctcgacggc tacgccgccc
    17341 gggaaatcac ctcagaccca ctcttcacca ccgcggctac aagcccccag atcgactcct
    17401 gccacgccct gatccaacga tgcggtctca acacacgaaa cctcaaccag ccagaccacg
    17461 cgctagtttc ccgtgccctg acctccagca gcaacgtcat ccaccgcagc ctggccccat
    17521 aggaagcccc cagtgcactc accacaaggt cgcaagaact cccgccagcg tgactgcatt
    17581 ccattgccat agacaaggcc gatggtgctg cgagtcgcca agggcctgta ccaggcctga
    17641 acgacgctgg ccacgcagcg atcctcgtcg gccagcacag cccgacatcc ccatggaccc
    17701 ggtgctgtcc tcctatctcg accacctcaa cgagctggtc taccggcgcg acctccccat
    17761 cgcgaaggaa tgtggtgacc actacaggcc gctggcgcta acctcaccct gcccccagcc
    17821 gacctcggcc ggatcgacgt ggtcttgtga gaggtcgtta agtccgattt ccctggttcg
    17881 cgatcgctcg atcgtggtac tgatcctcgt ccgggccgac tgttcgtcat gcccatgctg
    17941 agatgtgggc atggagcgaa gaccgtatcc gagcgactta tcggatgagc agtgggcgtt
    18001 gatcgagccg atgatcacag cctggaagca gggccgggta gcgcggtcgg cgaccgggga
    18061 tcccgggtcc tgcgacctgc gggaggtcgt gaacgcgatc ttctaccaga accggaccgg
    18121 ctgccagtgg cgctatctgc cccacgacct gccgacctgg tcggcggtgt tctactactt
    18181 cacgctgtgg cgtcaggacg ggctcgacca gcgggtccag gaactcctgc gttgccaggt
    18241 gagggagaga gcccgccgat tagaggaccc gtccctcgtg atcatcgaca cccagtccgt
    18301 gcgcgcggcc gccggtgtcc cgaagaccac gacgggactg gacgccacag gaggatgtcg
    18361 ggccgcaagc ggggactggc cgtcgacgtt ctggggctga tcatcggcgt cgtcgtgctc
    18421 gccgcgtccg cccacgacaa cgccgccggc accgctctgc tcgaccaggc ggccgagcgg
    18481 tgcgggatgc gcctggagaa ggctctggtg gaccagggct tcaaggacga ggttctcatc
    18541 cacggtgccc tgctggacat cgacgtcgag gtcgtccgcc gcaacccggc tgaccagggc
    18601 aaaggcttcg tcccgcagcc caagcggtgg atcgtggagc aggtcaacgg cacgttgatg
    18661 ctgcaccggc gcctcgcccg tgagtacgac caccgacccg acacctccac ctcgcgcgtc
    18721 tactgggcct cgatcgcgaa tatggtccgc cgcctcacca caccgagtcc ggcctggcgc
    18781 gacgccctcg ggctggccgc gtgaacgtca tcgagctcct ggccgacctt caggcccagc
    18841 acgacgagac caccgctcgg gccgttgaac tgcgcgaaca gatcaagcac ttgactaccg
    18901 ccctggccga gatcgaagcg cgactcgcgg acctggccac cacccggaag gtcatcgccg
    18961 aactcgcacc ggctggaggc caacccgcac cgcccgagac gaacaccgcc taccaggcca
    19021 tcgtgaacgc cttcaaccag caccccgacc aagagttccg agcccgtgag ctgcacgaac
    19081 tcctcggcat gcccaccgac gaggcatccg tcaacatcac ccgcagccgt ctcggacgcc
    19141 tcacccgcca aggcttcctc acccagcccg gacgcggccg ctaccagaaa cggacttaac
    19201 gacctctgag cagcaggggt atcactcagt gacccccgca gcgcggccgg ccgccaggcg
    19261 attgacgtga gcgcggatcc gtccgcggtc gtcgggaaaa acactgtccc actcagcgtc
    19321 caggcgaaac cacgcggcct gctggccctg ctcgccgcgg agcggcacat cgcgtccgac
    19381 aatcgcggcg taggacaggc ccagcgtcgg ggaccagtcg gcccgatagg agcggaccgc
    19441 cacggccgcg ggctgatcaa gcaactcggc ctgcaggctg gtctcctcaa acagttctcg
    19501 ggccgccgcc gcacgcggcc cctcgcccgg ctccaccttg ccgccgggcg gcacccagcc
    19561 acgcacacgg tgcttgacca acagcacgta ctccaagcgg gggtcggtga cccacacctc
    19621 ggccgcaagc ggctccatcg gacgctgcag cgcttcctcc aaccacgacc gagcgtcgtc
    19681 gaactcccac gcggcgaggc cagcatccgc tacagcctcg tccaaggtcg cctgcccctc
    19741 atcatcatga ctcacccgca ccaccctaga gcgacggacc agccacttgt tgcagggatg
    19801 gcggaccgcc ctccggtcgt gtccgggcga gccgccccgg ttctggaacg gttgggcgat
    19861 cgctcatggt gtccgcattt cacggaggag ccaacggcac aatgaccgaa cgtcggaact
    19921 gcgggcctga gtggtacggg gcggcgctca cctcctgacc gcaccacacc gcgccgcgcc
    19981 gcgccgcacc aacgaaccga tcgtgctggt tcacgtgcca ccgcaggagg tgtgccggcc
    20041 gcactgttgg tggaggtgta tcagcacggc gagggcgcgg tggagccgtt gccgtggatc
    20101 ctgatccgtg cagccgatgt cgatccagag caggtttggc agctcgccga cgcgatcgcc
    20161 accgcccggc atctgccgat caccgtcgtt ctgcccgcga ccccggcgac ccggcaggcc
    20221 ttcccccaca aaagagaggg ggacggccat gagcgacacc acgtgggccg ccggtgaaca
    20281 gcacctgggg cttcggcgac ctggactggt agccgacaag agcgaagggg ctgctgccgc
    20341 gatgatcgcg gcagcagccc cttcggctct tacaaggggt gtcacccgac acgtccccgc
    20401 tgcagatggc gcgcctacct gcctggcgag gtgtagcggg ctccgcccgg gggccgggcg
    20461 gtggtgtgcg gtggtgaagt cgcgggctgc tgctcacccg agggctggca gtgcgggcag
    20521 agtggcggcc gaggtcggtg tcgatggttc cccatccgcg gcagcgctcg cagtcgcggg
    20581 ccaagacagc gttggcgcag ggagcggggc ttgccccgtc ggtcataccg cgcttcctcc
    20641 gactgcgtcg ggcggtaagg ggcaggcgcg ccgatcgcgc acccgcttgg ttcgtcacat
    20701 gtgggtgaag atcttctcgg cgtcgaagcg ggagactggc tggcgagaga cgcgtgtctc
    20761 gtccgggtag ccgagcatga cgagcagcgt cgtggtgaag tcggtgtcgg tgaggtcgaa
    20821 cgcttcgtcg atcgtcgcgc ggtcgaagcc ttccagcggg gtggcgtcga ctccgagaga
    20881 agcggcggcc atcatggtcg cgccgaccac gaggtaggtg ttcttctcca gccagtggag
    20941 tacgtcgccg ccatagttct ccgactggat ctccacgaag ttggacgctc cagcctccca
    21001 tcccttctgg atctccgggt ccgcgaagcg accgtccgcg cgctccttcg cgaagatctc
    21061 ctgcaggtgc ttgtcgggaa tcgtcttgcg ggtcgtgaac acgatcgcgt gcgacgcgtt
    21121 tcgcaccttc tccgcgttgt ccgcgaagcg gccgacgaga gcgtccgcaa gcttgtcctt
    21181 gccggcctgc gactccagca catggaagtg gttcggctgg atgttgaccg tcgtcggcga
    21241 gctgcgcagg tagcgcagca ggagctgaat ggtctcctcc gggatcttct tgttcgggtc
    21301 gaagtaacgg gtgaggtgct tggtgatcag agtgtcgagc tccatggctg gctttcgttt
    21361 ccttgtcgga gagatcggtt caggaggcgg attacgggtg tgggagtcac gtcagtacgg
    21421 ggcgaaacgt cgctgtcatg gcgacctctg tgccagtcga cgtgtcgtga ggttgctggt
    21481 tacgcgcccg caccggggat gtcgacggcg gtgtcgttga cgttgttgag gtagttcgtg
    21541 agcaatgtga cgaccacgac ggtgacgatc gcctggatct cggggtccgt gtacccggcc
    21601 tcgcggaccg cggcgatgtc ctcgtcgccc acctgaccgc gggtctcgat cacctgctgg
    21661 gagaagcgag cgactgcggc acgcttggga tcggtggatc cgccggtgcg ggccagctcg
    21721 atctcctcgg tggacatgcc tgcgaggttc gtggagatgt atccgtgcag cgccgagcag
    21781 taggcgcagt tgttggagtg ggacgtggcc agcgcgatcg tgtggcgggt cttcgcgtcg
    21841 aggagcttcg cgatgctgcc ctgcaggctc atcacgatct ccaggacggc cgggttgccg
    21901 gcgagcgtgg tgaacatgcc cggagcgaag ccgaactgct tggcgatggt gtcgagcgtg
    21961 ccctgcgtct tggcgtcgat gtcggtgagc tcgggcgtgg tgagacgaga catggtggtg
    22021 gtcctccggg cggtatcagt tctgggctgc tcagcccact cagagtcaac ccgacgcgga
    22081 atgggctgtc aagcccaatc agtgttcatg ttgggctgct aagcccaatc tgcggggtag
    22141 ggtggtgaca tgcagatgaa cgatggatcg cgtgatcttc gcgggcgcac cggcaagggg
    22201 ctggcgacgc gaggtcgcat cctcgagcac gccgcggact tgatctacac gcggggggtc
    22261 cacgcgacga acaacgagct ggtgcgaaga tcagcgggga tcagcggctc gcagctgagc
    22321 cactacttcc cgaacaagga gagcctggtg cgcgccgtca tcgactggca ggccgagagc
    22381 gtgctcggct tccaccgaag cgaacggttc gccggcttcg aaacgatcga ggcgtaccag
    22441 gagtgggcgg acttctacgt cgtctccggg cgcccgttcg agaacggctg cagccttgga
    22501 tccctcgcga gcgagatcgt caaaaccgat ctggatgtcc gcgacgacct cacccgggtc
    22561 ttcgccgaat ggcaagacat cttccgagcg ggactcgagc ggatgcaaga tgccggacga
    22621 ctcgacgcgt cggcggatcc cgcgcaactc gcacacatgc tgatcgccgc ctaccaggga
    22681 ggcagcctgc tcgcgcagat cgcccgcgac gtagcaccat tgcgtgacgc gctgtatgcc
    22741 gcggtcgaaa atcttcgcgc ctacacaacg tcagacgacg tcgcgcgaac ctgatacgaa
    22801 gccccggcct cttgttccag agttccgtcg gcttgggcca gcgggccccc acaacgctgc
    22861 gggctcgcag ccagcctagg gctggccggc gccgttactc ctggccaggg acacagccag
    22921 cctccacgtg tcagtccccg cgtcgctggt cgtcgctttc ctggcgcagc tgctcagcgc
    22981 gctgagtgag cgcgtcgacg cgcgcggcaa cctctggatg gccgggcagg aggtgggcgc
    23041 gggtggcttc gagggggacc atcaggcgcg ccgcgtcgtc gcgggcgagg gctgcgtcga
    23101 tgtcggcgat ggctgatcgg gctccgggag gtaggtcggt cagctcggtg acgtgagcgg
    23161 ccaggcggcg caggtcagcg gcgttgtcgc gcgcccaggc agtgacgagg cggtcggccg
    23221 cgcggcggtc ccgggtcgct ttcacgcgct cctctcccgt gcagcccgcc gctcccggct
    23281 ggagacgtag gtagcggcgt tcggcggcct gacgactggc aaccccgagc ggaccggcca
    23341 ggtcggccca gctcgcgccg gcggctcggg cggtttcgat cagccctctc tcccagctgg
    23401 cgagctgctc gcgcacctcc cgcaggagca tcagcgaagc gagagcctgc ccggtgtcgc
    23461 cggcaggtgc cggccccgcg tcggcggcac gggcctcgcg caaggcgcgg tcgatggcac
    23521 cgagagcggt ggctgcggcc atgagcggta cggggccgtc gtcatcggca tccctcagcg
    23581 cggggcgcgc cgtagcgtcc atcagggccg cctttcgtca tccgtttgac gacacagggt
    23641 ttgtcatcat ctggatgaca tgctacaacg gatgtaggtg aagcgcattg gcagtcactg
    23701 cccgaaccct tggaggtgtt tcacgatgtt gatgcgcacc gaccccttcc gtgagctgga
    23761 ccgtctgacc cagcagctcc tgggaacgtc tggcacctgg tcgaggcccc aggcgatgcc
    23821 gatggacgcc taccgtgagg gcgaccgtta cgtgatcgcc ctcgacatgc ccggcgtgac
    23881 cccggacgcg atcgacatcg acgtcgaacg caacatgctc acggtcaagg ccgaacgccg
    23941 cccggtcgcc aaggccgacg acgtgcagat ggagctgtcc gaacggcccc tcggtgtctt
    24001 ctccaggcag ctcgtgctcg ccgacaccct ggacgccgag cacatcgagg ccgactacga
    24061 cgcgggtgtc ctgaccctgc gcatcccaat cgcggagcgg gccaagcccc gcaagatcgc
    24121 gatcacgtcc accggagacc gcaggcagat cagcggctga cccccagccg cgcttgatcc
    24181 cggcaagcag ccagcggagg acggtcaccg tacgcacgct cctcgggtcc gtcctccgca
    24241 tcaccgcaag ggggaatcgt ggccatgcga ccggaggtgt tcctggcaca ggtccaggaa
    24301 cgcggtgaat actccactcc gcaggaggcg gaccgggcgg cccgcgtcgt acttggactg
    24361 ctcggcgccc atgtggtcgg caaagagcgt gccgaactcg ccgcccgcct gccggagacc
    24421 tacgcactca tcttgctcaa cccactccag gccgtcgagc cactggacgc cgaacggttc
    24481 gtgcgggcca ccgccgcatg gatcgaaggc gccagcgaac agaccgccag gtgggacgtc
    24541 ggcgccgtcc ttagcgtggc tgccgacgag gccggaccag acctgctgcg acgactccta
    24601 ctccagttgc cgcccggcta cgacctgctg ttcggccacc ttgagccggc ctgaccttca
    24661 ccgccgaggg gcggggcacg ccgctcccgc cccacagcat cacaaacaga gaaaggcaca
    24721 ccgatgtacg cgcagcgcca agcggccgcc cccgtctcgg cgatgacgtt cgaggcgatg
    24781 gttgaacaag tccgctacga cggcgcctac ccaacccacg accgggcaga gcaagccgtt
    24841 cgccatgtga tggcaggcct gggccggcaa ttgatcggcg atgaacgcgt cgccctcgcc
    24901 gcccggcttc ccctcgaggc cgcacttgag ctcaccgccc aggttccgcg caccgaaccg
    24961 cttaccggat tcgattttgt cagcgacctg gccgcccgca ccggcggaac accagccacc
    25021 gcacgctggg acgccgggat cgtcttcgcg gtactccggc gcctgaccgg ggacgacctc
    25081 atcagcagcg tcctcgcaca gctgcccagc gggtacgcct tgctcttcgg ccgcgccgaa
    25141 ctagctccga ctgggtaacc cggtggacaa cctgcaggtg acgggcccca ctacccccga
    25201 acaccagcca gctcgctacc cgctcccctg acagcgccta ctcccgggtc ctcgcgcaac
    25261 gaggacccgg cagagcgccg atggcaggac agcccacatg cgcagtccat ccagcgctcc
    25321 acaaccgcag cgacgccagc aggaccagta agccaggggt gtcccactcc tgaactgaac
    25381 ctcgccgcgc caccccaacg acccgatcgt gctcgttcgc gtgccaccca agacgtgtgc
    25441 cagccgacca ccaccgtggt catccgttgg aacgctctcg gtctctgcgc agtggacgcg
    25501 ctctacccag acggtccccg actcgggtcg gcccggatcg acggtggcga actgtttccc
    25561 gcacgccatc gcaggccccg cttcacgtga actggtcggc gccgacaacg ccccaggact
    25621 gggtggcgga ccagtgggcg tttaccgtgc tgccgaggtc ggtgccgctg ggtatagcag
    25681 gctggtcgtg atcactcggc gcaggtcata acgtagccca agcgtgggtg aaggcgggcg
    25741 tcgcggacct cccgcggcct gccgggccgg cgacgtactg cgggagctgt gactgcagct
    25801 gggtcaccgg tgaggacggc caggccggca agtgcccctg tcggaccggc gagaggccgt
    25861 gaccgggcct cgatttcact caccggaatc agtggtgacg tgccgtgaaa attcaccgcc
    25921 ccgcatacaa ggacaaaggc ggatgagatg tgtcagtgcg ctcatgatct ctattggagg
    25981 cggtgagttg gagccgtacg gtgcgtcgta tgtcgcaccg cggcacccgc cgcatgatgc
    26041 gctgctgtcc cgggagcacc gtcccggtga gcgcgcgtca gcggcgggcg ttgctgcggt
    26101 tacgcagccg atgccagggg gaggccgtcc cgtgccgagc accaccgacc aacgccgccg
    26161 tcagaaccgc caggcccgtc agggagcagc agtggcggcc gccgtgttcg cgggcgttct
    26221 cgcccttgct gcctgtggtg gtgaccagga ctccgccaag ctggccgccg catcgggcag
    26281 cgccaaggct gcgccgtcga aggctgccgc cgtgtcgacg gatccgactc cggtcgccaa
    26341 aga
//
