LOCUS       NZ_FZOF01000010        21026 bp    DNA     linear   CON 02-JAN-2025
DEFINITION  Actinacidiphila glaucinigra strain CGMCC 4.1858, whole genome
            shotgun sequence.
ACCESSION   NZ_FZOF01000010
VERSION     NZ_FZOF01000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinacidiphila glaucinigra
  ORGANISM  Actinacidiphila glaucinigra
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Actinacidiphila.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900188405.1-RS_2025_01_02
            Annotation Date                   :: 01/02/2025 02:14:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,793
            CDSs (total)                      :: 8,707
            Genes (coding)                    :: 8,547
            CDSs (with protein)               :: 8,547
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1 (5S, 16S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 47 of 160
            Pseudo Genes (incomplete)         :: 136 of 160
            Pseudo Genes (internal stop)      :: 6 of 160
            Pseudo Genes (multiple problems)  :: 29 of 160
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:25:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 98395
            Orig. end                         :: 119421
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FZOF01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21026
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21026
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21026
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11026](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11026
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(607..622)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.64"
                     /tool="antismash"
     gene            719..1963
                     /locus_tag="CHF15_RS21780"
                     /old_locus_tag="SAMN05216252_11073"
     CDS             719..1963
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557861.1"
                     /locus_tag="CHF15_RS21780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11073"
                     /product="cytochrome P450 family protein"
                     /protein_id="WP_089225523.1"
                     /sec_met_domain="p450 (E-value: 2.7e-16, bitscore: 52.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MECPVTGHHAASPIVLDPLVGDLVAESTALREAGPLAAVELPGGV
                     PVWAVTHHAEARALLTDPRLVKDIAHWDAFTRGEIPADWALIGLANPGRSMLTVDGADH
                     RRMRALVAQALTPRRVEQMRARIEELTAGLLERVEEAAREGDVLDLKATFAYPLPMYVV
                     QELMGIDEAHLPRLKVLFEKFFSTQTPPAEVLATLGELAALMAKTVADRRAEPGDDLTS
                     ALIAASEDGDHLTDEEIQSTLQLMIAAGHETTISLIVNAVVNLLTHPDQLALVREGKAS
                     WESVVEETLRHSTPTSHVLIRFATEDVPVGDKVIAKGEALIVSYAAIGGDEKQHGPSAG
                     VFDITRDHPIRHIAFGHGPHVCPGAALSRLEASVALPALFERFPKLDLAVPAAKLRNKP
                     VVTQNDLYELPVTVH"
     gene            complement(2091..4190)
                     /locus_tag="CHF15_RS21785"
                     /old_locus_tag="SAMN05216252_11074"
     CDS             complement(2091..4190)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003955397.1"
                     /locus_tag="CHF15_RS21785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11074"
                     /product="PhoX family protein"
                     /protein_id="WP_089225524.1"
                     /transl_table=11
                     /translation="MRPHRLLPLLPRHDGGRSALTCRFKCGDACAHEAPNTSGNAYLGD
                     VVADALSRRTMLRTGAVVTLAAAAGGIAVTSGTDVAAAAPEPLHGGHGGHGGTVDPDAA
                     KGLRFRPVEPNTVDAVVVPEGYAQSVVIRWGDPILRGAPAFDQARQTAAAQAGQFGYNN
                     DFLHLFDLPGERGRQVLVANHEYTDEILMFPAYDAANPTREQVEIAWAAHGLSVVVVEE
                     ERHSGRLYPVSRHGLNRRLHTRTAFRLTGPAAGSPLLRTKADPTGTKVLGTLNNCAGGT
                     TPWGTVLSGEENFNQYFGNAASVTDPVTAERLKRYGIAGAASERKWERFDDRFDLAKEP
                     NEVNRFGWIVELDPFDPDSTPRKHTALGRFKHEAAQPRLTDDGRPVVYMGDDERFDYMY
                     KFVASKAMRHGTGRAVREHNLSLLDEGTLYVARLTGDSPAAEFDGNGKLPSDGEFDGSG
                     EWIKLASGTTSFVEGMTAEEVYLFTRMAADKAGATKMDRPEDVEPSPRTGRVYVALTNN
                     TNRGKAGSAGADEANPRSNNKHGHVLELAEFFDDPAADRFAWRLFLVAGDPADPATYFA
                     GFPKDDVSPISCPDNVAFDPHGNLWISTDGAPGTLGTHDALFGVAVKGDKRGQVRQFLS
                     VPKGAETCGPIVQDQRVLVAVQHPGETDASTYENPSSRWPDGGKRIPRPSVVVVWRKDG
                     RDIGV"
     misc_feature    complement(4206..4222)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.34"
                     /tool="antismash"
     gene            complement(4379..5317)
                     /locus_tag="CHF15_RS21790"
                     /old_locus_tag="SAMN05216252_11075"
     CDS             complement(4379..5317)
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018840175.1"
                     /locus_tag="CHF15_RS21790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11075"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_089225525.1"
                     /transl_table=11
                     /translation="MPIIVRPAAPEDAPVICDLLNAVDVVELGRPETDLATVESSLIHP
                     EADLERNSWLAFEDGALVAYGLLWDDSGAERIDADHYVLPAHQEAGERLLGLLQTRAAG
                     RAAENGAERAVVHLSLNTAPTMDTSRLTRRGWRTVRRYHVLTRPLSAAADPVPGPPTGL
                     TLRDCTAEADRRRAHELLQESFAEHFDHQRRTYRQWLDDLGQGIDWSLVWIASLEGAGD
                     VGAALSRDDRAAMAWIRSLGVRKEARGRGVAGHLLRHAFGVYAARGRDTIGLGVDTGNT
                     TGALRLYTAHGMTLHFAVDTWELTLPAATPA"
     misc_feature    5350..5361
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.83"
                     /tool="antismash"
     gene            complement(5398..6582)
                     /locus_tag="CHF15_RS21795"
                     /old_locus_tag="SAMN05216252_11076"
     CDS             complement(5398..6582)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557859.1"
                     /locus_tag="CHF15_RS21795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11076"
                     /product="hypothetical protein"
                     /protein_id="WP_089225526.1"
                     /transl_table=11
                     /translation="MSINQVRIAVALLSLALFAQTTFWLLYDIVVRGLPGAWSLWTTGW
                     VPGLSATSSLDLGLAALQLCAGLAALFRTRGAGGLLMTSCTVTLGFRLPAVWYLLLDSP
                     SDPWFGTLKGASLNAVGSTAVLAVVICLVLGGLLLLARHMEYEAAASNSVTGGVRPVKV
                     TATASGLLLAVLNVFYIGRNAVTAFQVGPGVLTDLIVGKGSGRAILAVPSPYQWVCLTV
                     LCGAGMLLAARRRPTAPGFSVGLSLFMMPSAFTELWGYAVGSMPVTAVDTSQSLLEFVG
                     SAAVVALIVGDVRRDRRPDDADLDVMTPAVPMRTAAGVPAVPVTPAVATTPAAPAAPAA
                     PAAPAAQDDEDDDAPEEAVEAVEITVPAQRDTDTDASTDAGASADRPATEAAGA"
     misc_feature    complement(6745..6759)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.24"
                     /tool="antismash"
     gene            7060..7326
                     /locus_tag="CHF15_RS21800"
                     /old_locus_tag="SAMN05216252_11077"
     CDS             7060..7326
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557858.1"
                     /locus_tag="CHF15_RS21800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11077"
                     /product="hypothetical protein"
                     /protein_id="WP_089225527.1"
                     /transl_table=11
                     /translation="MPPYPSLTHALVAALVDLTWFVEDADDERMDQDEALKALEGVAAV
                     VDRMTEGQRDGFLDLLAAMTAAETDPRRRAFLEDFPEDFGVVD"
     gene            complement(7337..8296)
                     /locus_tag="CHF15_RS21805"
                     /old_locus_tag="SAMN05216252_11078"
     CDS             complement(7337..8296)
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557857.1"
                     /locus_tag="CHF15_RS21805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11078"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_089225528.1"
                     /transl_table=11
                     /translation="MKAPTTRPFEASDVDAAAGLLAARHRRDLAGEPALDPGFAEPAAC
                     AALLRDAWERGARGAVAETADGTLAGYLLAVPGDDVRGRHVWTGPGHYAAHDGDVLRGL
                     YAHLSGPWLGEGRLHHYAVSAAHDLPVWLSQCFAYEQVHAVTDLVAGEAGFHDDVRAAG
                     PSDLAALEPLFRLVADAHTGPPVFAFIEQSFHEGLRPGHLELLEDPAVSYWLAEGPEGA
                     RGFCVMRPVPDDEVSPTAPRGSVELLLAATAPECRGSGVGRRLTEHALADAARSGFRVC
                     VTDWRAANPLSSVFWPRRGFRPVAHRLHRLLDPRLSQG"
     gene            complement(8319..9098)
                     /locus_tag="CHF15_RS21810"
                     /old_locus_tag="SAMN05216252_11079"
     CDS             complement(8319..9098)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557856.1"
                     /locus_tag="CHF15_RS21810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11079"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_089225529.1"
                     /transl_table=11
                     /translation="MSTFRDLLAEGEAVPTEGWDFSWFTGRATEQRPSWGYARLLADRA
                     ARAEAVLDVQTGGGEVMATVPLAPPVVAATESWAPNLAIARRNLAPFGATVVQAEDTAD
                     LPFPDGHFDLVVSRHPVVTRWDEVRRVLRPGGTYLSQQVGAGSVRELTDYLMGPRPVAV
                     HTQDPFTTTAGSSGVEATARAEAAGLEVVDLRQEALRMEFHDIAAVVHFLRKVIWIVPG
                     FSVDAYRERLAELYGFMERHGPFVAYSQRYLIEARKG"
     gene            complement(9190..9732)
                     /locus_tag="CHF15_RS21815"
                     /old_locus_tag="SAMN05216252_11080"
     CDS             complement(9190..9732)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981542.1"
                     /locus_tag="CHF15_RS21815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11080"
                     /product="hypothetical protein"
                     /protein_id="WP_089225530.1"
                     /transl_table=11
                     /translation="MHRRRRPYSAAVTAALLAALLGACGSPDSGAVAGSGPSATASPGP
                     RTPVAKADPPVTGALDDHRHVARRTTTGRRPHMVQRCTDRTRRVRHTSSSGSGKRKSTR
                     TWYTTEHYKDCRKVQQGTESYTRVVSAERWCVELDDVGGDRTRDDVWFKVDSATYGRAA
                     DAEEGTRMSFTPLATGC"
     gene            10001..11026
                     /locus_tag="CHF15_RS21820"
                     /old_locus_tag="SAMN05216252_11081"
     CDS             10001..11026
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="CHF15_RS21820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11081"
                     /product="terpene synthase family protein"
                     /protein_id="WP_143681606.1"
                     /sec_met_domain="T1TS (E-value: 1.9e-67, bitscore: 221.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKTSAFVHIDGPGGRASHSGTVRERAGGPVRVPGPSLLNPGLQE
                     VEPQVMAWARRAGLLSALTSGQAGRERQVAMAAHVWPWAPPGRLAELARLTLWMFAVDD
                     DSDAGPATGTGAELEAMAHAVGGWARAVPVSAPPAVRVLDEVVPRVTGVMGPAWGDRFR
                     RHLVAWIRTNQDMLRFRGGHEVPTPEAYIAWRRVSGATGWCFDLIEYAQESELPAAIWF
                     SPACRALREAAADVIGWTNDLFSVEKELRTGETTNLVLVLRHHHGLTLEEAVDETRLWH
                     ARRVAALRTATRDLYAGALAADLTPAQLAAVCHYADGIHAWARGFLDFSLASARYGDCG
                     G"
     gene            11084..13735
                     /locus_tag="CHF15_RS21825"
                     /old_locus_tag="SAMN05216252_11082"
     CDS             11084..13735
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024816.5"
                     /locus_tag="CHF15_RS21825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11082"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_143681607.1"
                     /transl_table=11
                     /translation="MVAAVWGRIAGAAGYLLRMFAGLARPVLTLLLGPPGAVAGAATET
                     VAASGGRALEQTAGRRRALPGLLRISRRGTAPLVADVDDPIGLGVHPAAPGGGGTAGFG
                     RVPVFVGRDAMPQAEAVLSGGRGFLLLVGDSTAGKTRLAYEVVRKHFPRHRLVVPDSRE
                     AMVALVDPVSRWYRAVVWLDDLENYLGAGGLTAGHVQRLLEAGSARVAVVATISARQHI
                     RFGARSAADDEPGGDVLRSGREVLRLASVVRVDRTWSEAELARAQHHTDDPRIRAAVNG
                     ARTGSRGVAEYLAAAPQLLDDFRNAWAAGARPRAAALVAGAVDARRAGHHEPLPEDVLR
                     RLHEIHLDLRGGGSLRPEPWEEALNWATDPLHATSSLLLPRDDGAYLAFDYLHQTLDEQ
                     VPPPRIPDAVWEILIDHADPVRALDIGATAYQRGDLRHAMAAFDKAGADPGQLPRQWYA
                     TCVGEAGDPRRAADLYHDLVAEAERRGGPDAKETLENRNSHARYRGMAGHPAEAVDLLR
                     GVIEDRTRILGREHSHTLNSRNNLALFLGESGRLDEAVAVYQSVLADRTRLLGADHPHT
                     LSSRYGYAYLLGDAGRPGQAARLFDSLVADRTRTQGPYHPYTLNNRRHHAHFLGEAGHA
                     ARAAGLFEELLEDCLKVLDPLHPDTLASRHGQARFLGEAGDPGRAAALLDGLIADGRRA
                     AVHGPDSPIPLLWRRYQAVFLSEAGATEEAVRLLDTLLTESGGILDAGHPQLFAVRAAH
                     ARCVLRAGRTGEAAALYGRLVDDCRDRLGEDHPQTLTARGGRARCLAAAGRHGEAADLL
                     EILVQDRTRVLGDDHPSTLNSRNAHACSVGAAGDSARAGRLLRQVLQDRVRHLGEEHPW
                     GDRTRDELARFT"
     gene            complement(13778..15355)
                     /locus_tag="CHF15_RS21830"
                     /old_locus_tag="SAMN05216252_11083"
     CDS             complement(13778..15355)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557853.1"
                     /locus_tag="CHF15_RS21830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11083"
                     /product="aldehyde dehydrogenase (NADP(+))"
                     /protein_id="WP_089225533.1"
                     /sec_met_domain="Aldedh (E-value: 7.2e-46, bitscore: 150.1,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLTGEILIGASSVPASEGTMKALDPATGEPVGPEFALGGAAEVD
                     RAARLADEAYDTYNRTGLAERAAFLELIADRLEAIKGELAERAALETGLPVAQLEAEAV
                     KSAGQFRQFAEVVRQGRFRQAAVDPAQPERQPRPRMDHRMQKIAIGPVAVFGASNFPIS
                     YSVAGGDTAAALAAGCPVILKAHNAHPGASELQGRVIQGAVADSGLHEGVFSMLRGPGN
                     AIGEALVDHPLVKAVTFTGSEGGGMALYRRAQLRPDPIPVFAEMTSVNPTFVLPAALAA
                     RGGEIGDGFAERMLVNVGQACLKPAVLLAVDGPGYAAMREAAAARVSAMGARTMLTPGI
                     HDAYGRGAQRLRGAGAATVAAGPEPEGAFEGRAQLLEVDGDRFLAEPTLADEVFGPAAL
                     LVRLTGVEQMTEMARSFRGQLSATMHLDDADHPQAARLLPVLERRTGRIVVNAFAHPQE
                     VGHATIHGGPFPATTDSRFTSVGMSAIERFLRPVTYQGFPDALLPEALAPDNPLGLWRL
                     VDGHVTRG"
     gene            complement(15357..15986)
                     /locus_tag="CHF15_RS21835"
                     /old_locus_tag="SAMN05216252_11084"
     CDS             complement(15357..15986)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557852.1"
                     /locus_tag="CHF15_RS21835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11084"
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="WP_089225534.1"
                     /transl_table=11
                     /translation="MTDTYDPTRTAILLVDPYNDFLSEGGKVWPALEPVATEVGLLDNL
                     RAVVGAGRAAGQKVFFVPHRRWQEGDYEDWEHPNPTHRIIQERRTFAFGTWGGEFHPDF
                     RPADGDVVIQEHWSQSGFANTDLDFRLKQQGITHVIVIGLLANTCIESTGRYAMELGYH
                     VTLVRDATAAYRPEMMHAAHELNGPTYAHSITTTADLLSTLENGDH"
     misc_feature    16027..16042
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.36"
                     /tool="antismash"
     gene            16082..16534
                     /locus_tag="CHF15_RS21840"
                     /old_locus_tag="SAMN05216252_11085"
     CDS             16082..16534
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025292.5"
                     /locus_tag="CHF15_RS21840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11085"
                     /product="lipocalin-like domain-containing protein"
                     /protein_id="WP_179279900.1"
                     /transl_table=11
                     /translation="MAPDELREALIGAWRLVSYAATDVATGEVVEPFGPRPRGLITYGP
                     DGHMSAQIMRAGRPDFRHGRLEEGLPGELAAAAAGYLAYAGTFEVPAEDTVVHRVELSL
                     FPNWVGGAQTRIAALDGRRLRLSLPGAARIWGALRTGVLTWERAGR"
     gene            complement(16557..17852)
                     /locus_tag="CHF15_RS21845"
                     /old_locus_tag="SAMN05216252_11086"
     CDS             complement(16557..17852)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557850.1"
                     /locus_tag="CHF15_RS21845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11086"
                     /product="MFS transporter"
                     /protein_id="WP_089225536.1"
                     /transl_table=11
                     /translation="MTTAATRPDVKRGTLPVFATATAITVANIYFTQPLLDQIARGFGI
                     SASAAGLVATAGQIGYALGIVAVVPLADRARLRRLSRVLLAVTAVALLAGAAAPSVALL
                     GMATLVLSASTVLPQVIMPTVASMAAPGQAGRVLGAVGTGLTMGALLSRTASGLIAQAA
                     GTWRAGFLVAAAATAALLLILPRYMPAGRPAGAEASGGYGRLLASLPRLLVDHAPLRLS
                     AALGATVFASFSAFWSTLAFHLTAPPIGLGPAVVGLFGLCSVPGALAARYSGRLTDRWG
                     PLAVNTLSVIAAVAAFALFGVAGRSLVVLAVGCNLLGYGVTSGQIANQARIFTAAPGIR
                     GRLNTVYMFAVFGGGAVGSAVAGVLFSASGWHGVVAGGLGFLILAGLTLAWHGLRARNG
                     GSGRAARRGDGTGPGRTDTATATAAATPAVRG"
     misc_feature    complement(17977..17992)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.05"
                     /tool="antismash"
     gene            18093..18686
                     /locus_tag="CHF15_RS21850"
                     /old_locus_tag="SAMN05216252_11087"
     CDS             18093..18686
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.5"
                     /locus_tag="CHF15_RS21850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216252_11087"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_179279901.1"
                     /transl_table=11
                     /translation="MGHSQAAKAESREKVLRIAARRIREEGMTRPGVADLMKEAGLTHG
                     GFYKHFSSREDLMGQAAALALADGEGKMADAARRDPVAPRSGLIDAYLSARHRDAPGTG
                     CALVTLGATAGRGDEALKEAYEQQVRKYLELIGEAAQGGDPEVAQADAMVTLSALVGAM
                     LISRAVADPGFSDEILATVAGRLKDADTHVPAEV"
ORIGIN
        1 tcctggtgaa ggcggtcaag gacctggtcg acggcggccc ggacgccatc gccggccaga
       61 cgcacgtcta caccgcgatg accgaactgc tcgaggcgaa gaaggagcag ccgggcgcgg
      121 acgtcgtctc gcggatgctc gccgaccggt acgacttctc cgacgaggag atcgtgcagg
      181 acctgatggt gatgaccgtg gccgggcacc agcccaccgc ggactggatc ggcaactcgc
      241 tcaggctgat gctcaccgac gaccgcttcg ccgcctcgtt caccggcggc cggcacagcg
      301 tcgggcaggc catgaacgag gtcctgtggg aggacacccc cagccagaac atcgccgggc
      361 ggtgggccag ccgcgacacc cggctcggcg ggcgccagat cgcctccggc gacctgctca
      421 tcctcggctt cgccgcggcc aacgcagacc cccaggtgca cctggaggcc ggtgcctcca
      481 ccaacggcaa caacgcctgg ttctccttcg ggcacggcga gcaccgctgc ccgttcccgg
      541 cccaggagat cgccgaggcc atcgcccgca ccggcatcga ggtgctgctg gaccggctgc
      601 ccgacatcga actggcggtc gaccccgccg atctggtgcg ccgtccgtcc ccgtggctgc
      661 ggggcatgac caagctcccc gtgcgcttca cacccacccc cgtgctagga gaactctgat
      721 ggaatgcccg gtcaccggcc accacgcggc ctccccgatc gtgctggacc cgctggtggg
      781 cgacctcgtc gccgagagca ccgcgctgcg tgaggcgggc ccgctggccg cggtcgagct
      841 ccccggcggg gtgccggtgt gggccgtgac gcaccacgcc gaggcccgcg cgctgctgac
      901 cgacccgcgg ctggtgaagg acatcgccca ctgggacgcc ttcacccgcg gtgagatacc
      961 cgccgactgg gcgctgatcg gcctggccaa ccccggccgc tccatgctca ccgtcgacgg
     1021 cgccgaccac cgccgcatgc gtgccctggt cgcccaggcg ctgaccccgc gccgcgtgga
     1081 gcagatgcgg gcccggatcg aggagctgac ggccggtctc ctggagcgtg tcgaggaggc
     1141 ggcgcgcgag ggcgacgtac tcgacctcaa ggccaccttc gcctacccgc tgccgatgta
     1201 cgtcgtacag gagctgatgg gcatcgacga ggcccacctg ccgcggctga aggtgctgtt
     1261 cgagaagttc ttctccaccc agaccccgcc cgcggaggtc ctcgccaccc tcggcgagct
     1321 cgcggccctc atggccaaga ccgtcgccga ccggcgcgcc gagcccggcg acgacctcac
     1381 cagcgctctc atcgcggcct ccgaggacgg tgaccacctc accgacgagg agatccagag
     1441 caccctgcag ctcatgatcg ccgcggggca cgagaccacc atctccctca tcgtgaacgc
     1501 ggtcgtgaac ctgctcaccc accccgacca gctcgcgctg gtgcgggagg gcaaggcgag
     1561 ctgggagtcg gtggtggagg agaccctgcg ccactccacg cccacctcgc acgtgctgat
     1621 ccgcttcgcc accgaggacg tccccgtggg cgacaaggtg atcgccaagg gcgaggcgct
     1681 gatcgtctcc tacgcggcga tcggcggcga cgagaagcag cacggcccga gcgccggcgt
     1741 cttcgacatc acccgcgacc accccatccg gcacatcgcc ttcggccacg gcccccacgt
     1801 gtgcccgggc gccgcgctgt cccggctgga ggcctcggtg gcgctgcccg ccctgttcga
     1861 gcgcttcccg aagctcgacc tggcggtccc ggcggcgaag ctgcgcaaca agcccgtggt
     1921 cacccagaac gacctctacg agctgccggt caccgtccac tgacctaccg tcggtgtccg
     1981 gcacctcccc gcgccgctcg tgccggtgcg gggcggtgcc ggtcccgtcc ggccccgtga
     2041 cgacgaccgc gggacggccc cgcccggcac gccgggcggg gccgtctccg tcagacgccg
     2101 atgtcgcggc cgtccttgcg ccacaccacg acgacggagg ggcgggggat ccgcttgccg
     2161 ccgtcgggcc agcgcgagga cgggttctcg tacgtggagg cgtcggtctc gccggggtgc
     2221 tgcaccgcga ccaggacgcg ctggtcctgg acgatcgggc cgcacgtctc ggcacccttg
     2281 ggcacgctca ggaactgccg gacctgaccg cgcttgtcac ccttgaccgc gacaccgaag
     2341 agggcgtcgt gggtgccgag ggtgcccggc gcgccgtcgg tggagatcca caggttgccg
     2401 tgcgggtcga aggccacgtt gtccgggcac gagatcgggc tgacgtcgtc cttcgggaag
     2461 cccgcgaagt aggtggcggg gtcggcgggg tcgcccgcga ccaggaacag ccgccacgcg
     2521 aagcggtcgg cggccgggtc gtcgaagaac tccgccagct ccagcacgtg cccgtgcttg
     2581 ttgttgctgc gcggattggc ctcgtcggca ccggcggatc cggccttgcc gcggttggtg
     2641 ttgttggtga gcgccacgta gacgcgaccg gtgcgcgggc tgggctcgac gtcctcgggg
     2701 cggtccatct tggtggctcc ggccttgtcc gccgccatgc gggtgaagag gtagacctcc
     2761 tcggcggtca tgccctccac gaaggaggtg gtgccgctcg ccagcttgat ccactcgccg
     2821 gagccgtcga actcgccgtc cgagggcagc ttcccgttgc cgtcgaactc ggcggccggg
     2881 ctgtcgcccg tcagccgggc gacgtagagc gtgccctcgt ccaggagcga caggttgtgc
     2941 tcgcggaccg cccggccggt gccgtggcgc atcgccttgc tcgccacgaa cttgtacatg
     3001 tagtcaaagc gctcgtcgtc gcccatgtag acgacggggc ggccgtcgtc ggtgaggcgg
     3061 ggctgcgcgg cctcgtgctt gaagcggccg agcgcggtgt gcttgcgggg cgtcgagtcc
     3121 gggtcgaacg ggtcgagctc cacgatccag ccgaagcggt tgacctcgtt gggctccttg
     3181 gccaggtcga agcggtcgtc gaaccgctcc cacttgcgct cgctggccgc gccggcgatg
     3241 ccgtagcgct tcagccgctc cgcggtgacc gggtcggtga ccgaggccgc gttgccgaag
     3301 tactggttga agttctcctc gccggacagc acggtgcccc acggggtggt gccgccggcg
     3361 cagttgttga gggtgccgag gaccttcgtg ccggtagggt cggccttggt gcgcagcagg
     3421 gggctgcccg cggcggggcc ggtcagccgg aaggcggtcc gggtgtggag ccggcggttc
     3481 aggccgtgcc ggctcaccgg gtacaggcgg ccggagtgcc gctcctcctc gaccacgacc
     3541 acgctgagcc cgtgcgcggc ccaggcgatc tcgacctgct cgcgggtggg gttcgccgcg
     3601 tcgtaggccg ggaacatgag gatctcgtcg gtgtactcgt ggttggcgac gagtacctga
     3661 cggccgcgct cgccgggcag gtcgaacagg tgcaggaagt cgttgttgta gccgaactgg
     3721 ccggcctgcg ccgcggcggt ctgccgcgcc tggtcgaacg cgggggcgcc gcgcaggatg
     3781 gggtcgcccc agcggatcac gacgctctgg gcatagccct cggggacgac gacggcgtcc
     3841 acggtgttcg gctcgacggg ccggaagcgc aggcccttgg cggcgtcggg gtcgacggtg
     3901 ccgccgtgac cgccgtggcc cccgtgcagc ggctcgggcg cggcggcggc cacgtcggtg
     3961 ccggacgtga cggctatgcc gcccgcggcg gcggccaggg tgaccacggc gccggtccgc
     4021 agcatggtgc ggcgggagag ggcgtccgcg acgacgtcgc cgaggtaggc gttgccgctg
     4081 gtgttcgggg cctcgtgggc gcaggcgtca ccgcacttga accggcaggt gagagcggac
     4141 ctgccgccgt cgtgacgggg gagcagcgga agaagtctgt gcggccgcac agtgcctcca
     4201 agtctatgtt ccggtatagc gaataccaag ggacggtaaa gagccctgtt ctcgcgggag
     4261 tggccggaac gtgaaccgcg aatgaaccgg tgagcgcggc gcggggttcc cgtccgcgcg
     4321 cccgacgcga gccggcgccc acctgggcgg cgtccgcacc gcgccgcggg cggcgcgctc
     4381 acgccggggt ggccgcgggc agcgtcagct cccaggtgtc cacggcgaag tggagggtca
     4441 tgccgtgcgc ggtgtacagc cgcagggccc ccgtggtgtt gccggtgtcc accccgagcc
     4501 cgatggtgtc gcggccgcgg gcggcgtaca ccccgaaggc gtggcgcagc agatggccgg
     4561 cgacgccccg gccccgcgcc tccttgcgca cgcccaggct ccggatccac gccatggccg
     4621 cgcggtcgtc acggctcagc gccgctccca cgtcccccgc gccctccagc gaggcgatcc
     4681 acaccaggga ccagtcgatg ccctggccga ggtcgtccag ccactgccgg taggtgcgcc
     4741 gctggtggtc gaagtgctcc gcgaagctct cctgcaggag ttcgtgcgcg cggcggcggt
     4801 cggcctccgc tgtgcagtcg cgcagcgtca gtccggtagg gggcccgggg acggggtccg
     4861 cggcggcgga cagcgggcgg gtcagcacgt ggtagcgccg taccgtcctc cagccgcgcc
     4921 gcgtcaggcg ggacgtgtcc atggtgggcg cggtgttgag ggacaggtgg acgacggccc
     4981 gctccgcgcc gttctccgcg gcgcgtccgg cggcccgggt ctggaggagg cccagcagcc
     5041 gctcgcccgc ctcctggtgg gcgggcagga cgtagtggtc ggcgtcgatg cgttcggcgc
     5101 cggagtcgtc ccacagcagt ccgtaggcga cgagcgcgcc gtcctcgaag gccagccagg
     5161 agttgcgttc caggtccgcc tcgggatgga tcagcgacga ctcgaccgtc gccaggtcgg
     5221 tctcgggccg cccgagctca acgacgtcga cggcgttgag caggtcgcag atgacggggg
     5281 cgtcctcggg ggcggccggc cgcacgatga tgggcatggc gcaaccctcg gcaccggcac
     5341 cggctccgcg caaacgtttt tcgcggcgga gccggtccgg ccgggacggc gcccgcgtca
     5401 ggcgcccgcg gcctcggtcg ccggacggtc cgcgctcgcg cccgcgtcgg tgctcgcgtc
     5461 ggtgtcggtg tcgcgctggg cggggacggt gatctccacg gcctcgacgg cctcttcggg
     5521 tgcgtcgtcg tcctcgtcgt cctgggctgc cggtgcggcg ggtgcggcgg gtgcggccgg
     5581 tgcggcgggc gtggtggcta cggcgggcgt gacgggtacg gcaggtacgc ctgccgcggt
     5641 tctcatcggc acggcggggg tcatgacgtc gaggtcggcg tcgtcgggcc ggcggtcgcg
     5701 gcggacgtcg ccgacgatga gggcgaccac cgccgccgaa ccgacgaact ccagcaggct
     5761 ctgcgaggtg tccacggcgg tcacgggcat cgagccgacg gcgtagcccc acagctccgt
     5821 gaaggccgaa ggcatcatga agagcgacag gcccaccgag aagcccgggg cggtgggccg
     5881 ccgcctggcg gcgagcagca tgccggcccc gcacagcacg gtcaggcaca cccactggta
     5941 cggcgaagga accgcgagga tggcgcgccc gctgcccttg ccgacgatca ggtcggtgag
     6001 cacaccaggg ccgacctgaa aggccgtcac cgcgttccgg ccgatgtaga agacgttgag
     6061 caccgcgagc agcagaccgg aggcggtggc cgtcaccttc accgggcgga ccccgccggt
     6121 caccgagttc gaggcggcgg cctcgtactc catgtgccgt gcgagcagga ggagcccgcc
     6181 gaggacgagg cagatgacca ccgcgaggac ggcggtgctg cccaccgcgt tcagcgaggc
     6241 gcccttgagg gtgccgaacc acgggtcgga gggggagtcg agcagcaggt accagaccgc
     6301 cggaaggcgg aagccgaggg tcaccgtgca cgaggtcatc agcaggccgc cggcgccgcg
     6361 ggtgcggaac agggcggcca gaccggcgca gagctgcagc gccgccaggc cgaggtcgag
     6421 cgaagaggtc gccgaaaggc ccggcaccca tcccgtcgtc cacagcgacc aggcgccggg
     6481 cagaccgcgg acaacgatgt cgtagagcag ccagaacgtc gtctgggcga agagcgcgag
     6541 gctgagcaag gccacggcta tccgcacctg gttgatcgac atccccggac ggttcatggc
     6601 gcgctgtccc ctcgacggcc aaacgtggtt gagttcacaa cattcccaat gacggtgcag
     6661 agcataaacg gtcacccatg tgcccgcgcc aatccgcccc cgaggtgccg gccttgcgga
     6721 accgcgcgag aacggtgtgc caacggaaaa tgaatgacgg cccatcagga gacgccggcc
     6781 ggacttgtcg agtggcccag ggccgcggtc gaacaggcaa cgctgaatgg tgagttgggc
     6841 gtaccgtcga gagcggggcg gtcacgtgcg gggcaggtgc cggccgcgac gtggcacgcg
     6901 tggtactccg tgaagcgggc gcggccccag ggcggaccgt acgcgcccgc cggaacccgc
     6961 ccgggcggct gcggcaccga cctgggcgcg gcagtgtcgg cgccccgtga tgggatgccg
     7021 gggaacaccg cagccgtagc ccgcagggag aacacgccga tgcctccgta cccttcgctc
     7081 acccacgccc tcgtggcggc tctcgtggac ctcacctggt tcgtcgagga cgcggacgac
     7141 gagcgcatgg accaggacga ggcgctgaag gccctggagg gtgtggccgc cgtggtcgac
     7201 cggatgacgg agggccagcg ggacgggttc ctcgacctgc tggcggcgat gacggcggcc
     7261 gagaccgatc cccggcgccg cgcgttcctg gaggacttcc cggaggactt cggcgtcgtg
     7321 gactagcccg cccggctcag ccctgtgaca gccgcgggtc caggaggcgg tgcagccggt
     7381 gggcgacggg acggaagccg cggcgcggcc agaacaccga cgagagcggg ttcgccgccc
     7441 gccagtccgt cacgcacacg cggaatccgc tccgcgccgc gtccgcgagg gcgtgctcgg
     7501 tgaggcggcg ccccacaccg ctgccccggc actcaggggc ggtcgcggcg aggagcagtt
     7561 cgaccgagcc gcgcggcgcg gtcggcgaga cctcgtcgtc gggtacgggc cgcatgacgc
     7621 agaagccccg cgccccctcc ggcccttcgg cgagccagta ggacacggcg gggtcctcca
     7681 gcagctccaa gtgccccggc cgcaggccct cgtggaagga ctgctcgatg aaggcgaaga
     7741 ccggcgggcc cgtgtgcgcg tcggcgacca ggcggaacag cggttccagc gcggcgaggt
     7801 ccgaaggccc ggcggcccgt acgtcgtcgt ggaagccggc ctctcccgcc accagatccg
     7861 tcacggcgtg gacctgctcg taggcgaagc actgcgacag ccagaccggc aggtcgtgcg
     7921 cggccgagac ggcgtagtgg tgcagccgcc cctcgccgag ccatggaccc gacaggtgcg
     7981 cgtacaggcc gcgcaggacg tccccgtcgt gtgccgcgta gtgcccgggc cccgtccaca
     8041 catggcgtcc gcgcacgtcg tcgccgggca cggccaggag gtatccggcg agcgtgccgt
     8101 ccgccgtctc cgcgaccgct ccgcgcgcgc cccgctccca ggcgtcccgc aggagggccg
     8161 cgcaggccgc cggttcggcg aaaccggggt cgagcgccgg ttccccggcg aggtcgcggc
     8221 ggtggcgggc ggcgaggagg ccggccgcgg catcgacgtc ggaggcctcg aacggcctgg
     8281 tcgtcggcgc tttcaccagg ggtgccttct ttccggggtc agcccttgcg ggcctcgatc
     8341 aggtagcgct gcgagtaggc cacgaagggc ccgtgccgtt ccatgaagcc gtacagctcc
     8401 gcgagccgct cgcggtaggc gtccacggag aagcccggca cgatccagat gaccttgcgc
     8461 aggaagtgga ccacggcggc gatgtcgtgg aactccatgc gcagcgcctc ctggcgcagg
     8521 tccacgacct ccaggcccgc cgcctcggcg cgggcggtgg cctcgacccc gctggagccg
     8581 gccgtcgtgg tgaaggggtc ctgcgtgtgc acggcgaccg gccgcggccc catcaggtag
     8641 tccgtcagct cccgcaccga gcccgcgccg acctgctggg acaggtaggt gccgccggga
     8701 cgcagcaccc ggcgcacctc gtcccagcgg gtcaccaccg gatgccggct gacgacgagg
     8761 tcgaagtggc cgtcggggaa ggggaggtcg gccgtgtcct cggcctggac gacggtggcg
     8821 ccgaagggtg ccaggttgcg gcgggcgatc gccaggttgg gcgcccagga ctccgtcgcc
     8881 gcgacgaccg gcggggcgag gggcacggtc gccatgacct ccccgccgcc ggtctggacg
     8941 tcgaggacgg cctcggcccg ggcggcccgg tccgcgagga gccgggcgta accccaggac
     9001 gggcgctgtt cggtggcgcg gccggtgaac caggagaagt cccagccctc ggtcgggacg
     9061 gcctcccctt cggcgaggag gtctcggaac gtggacatgg gcgcgaggat ggcagacgcc
     9121 cccggcgggg cgcatccgga ttacgccggg gcggcggcgc tccgcgtcgt cccgtcccgc
     9181 ggcgggccgt cagcagccgg tcgccagggg ggtgaaggac atccgggtgc cctcctccgc
     9241 gtcggcggcc ctgccgtagg tggcggagtc gaccttgaac cagacgtcgt cccgggtgcg
     9301 gtcgccgccg acgtcgtcca gctcgacgca ccagcgttcc gccgacacca cgcgcgtgta
     9361 ggactcggtg ccctgctgca ccttccggca gtccttgtag tgctcggtgg tgtaccaggt
     9421 ccgggtcgac ttgcgcttgc cggaaccgct cgaggacgtg tgccgcaccc gccgggtgcg
     9481 gtcggtgcac cgctgcacca tgtgcggccg ccgcccggtg gtcgtcctgc gcgccacgtg
     9541 ccggtggtcg tccagcgctc cggtgacggg cgggtccgcc ttcgcgaccg gggtacgggg
     9601 gcctggggaa gcggtggccg acggtccgga tccggccacg gcaccggagt ccgggctccc
     9661 gcaggcaccc agcagggcgg ccaggagcgc ggcggtcacg gcggcggagt acgggcggcg
     9721 gcgtctgtgc actgctctcc tcggtgaacg tgaaggtgac gccgaaggcg gaggtgaacg
     9781 gcgtcgcggg cggtcggtgc ccgcccggat catgacgcga tgcgaacggc ccgggttccc
     9841 gcatcgcccg cccggttgtg tcggcgcccg ccctgcctct gacgtcgcct gcccgttcct
     9901 ggcgtccgat ggccgaacgc tgggtaggaa ccgggacggg gatggctgga agtcgtagtc
     9961 cttgcccggg ccgccgacgg cccgggaagg ggggatctcg gtgggtaaga cgtctgcgtt
    10021 cgtccatatc gacggcccgg ggggacgggc ctcgcacagc gggaccgtac gggagcgggc
    10081 cggggggccc gtccgcgtac cgggcccgtc gctgctcaac cccggtctgc aggaggtgga
    10141 gccgcaggtc atggcctggg cccggcgcgc cggtctgctg tccgcgctga cctcgggtca
    10201 ggccggccgg gagcggcagg tcgccatggc cgcgcacgtg tggccgtggg cgcccccggg
    10261 ccgcctggcg gagctggccc ggctcaccct gtggatgttc gccgtcgacg acgacagcga
    10321 cgccggaccg gccaccggga ccggagcgga actcgaggcc atggcgcacg ccgtcggcgg
    10381 ctgggcgcgc gccgtccccg tgtcggcgcc accggccgtc cgcgtcctgg acgaggtggt
    10441 gccgcgggtg accggtgtca tggggccagc ctggggcgac cgtttccgcc gtcacctcgt
    10501 cgcgtggatc cgcaccaacc aggacatgct ccggttccgc ggcggccacg aggtgcccac
    10561 ccccgaggcc tacatcgcct ggcggcgggt ctccggtgcc acgggctggt gcttcgacct
    10621 catcgagtac gcccaggagt cggaactccc cgcggcgatc tggttctcgc cggcctgccg
    10681 cgcgctgcgg gaggccgccg ccgacgtcat cggctggacc aacgacctgt tctcggtgga
    10741 gaaggagctg cgcaccgggg agaccaccaa cctggtcctc gtccttcgcc accaccacgg
    10801 actgacgctg gaggaggccg tagacgaaac gcggctgtgg cacgcccgcc gtgtcgccgc
    10861 cctgcgcacc gcgacgcgcg acctgtacgc cggcgccctc gcggccgacc tgaccccggc
    10921 gcagctggcg gcggtctgcc attacgccga cggcatccat gcctgggccc gcggcttcct
    10981 cgacttctca ctggcctccg cccgttacgg cgactgcggg ggatagccgg cggcgccacc
    11041 gggaatgcac cacggaaggg ggagccaggg ggaacggggg tacgtggtgg ctgccgtgtg
    11101 ggggcgtatc gcgggcgctg cgggttacct gctcaggatg ttcgcgggcc tggcccggcc
    11161 cgtgctgacc ttgctgctcg gtccgccggg agcggtggcc ggcgcggcga ccgagaccgt
    11221 ggccgcctca ggaggcaggg cgctggagca gacggccggt cgcaggcggg cgctgcccgg
    11281 tctgctgcgg atctcccggc gcggcacggc gccgctggtg gcggacgtgg acgaccccat
    11341 cggcctcggt gtccacccgg ccgcgccggg cggcggcggg acggcgggct tcggccgcgt
    11401 cccggtgttc gtcggccggg acgcgatgcc gcaggcggag gcggtgctga gcgggggccg
    11461 gggcttcctg ctgctggtgg gggactccac ggcgggcaag acccgcctgg cgtacgaggt
    11521 ggtgcgcaag cacttcccgc gccaccggct ggtcgtcccg gacagccggg aggcgatggt
    11581 cgcgctcgtc gacccggtct cccggtggta ccgggccgtg gtgtggctgg acgacctgga
    11641 gaactacctc ggcgcgggcg gattgacggc gggtcacgta cagcggctgc tggaggccgg
    11701 atcggcgcgg gtcgccgtcg tcgcgaccat cagcgcccgt cagcacatcc gcttcggcgc
    11761 ccgctccgcc gccgacgacg agcccggcgg cgacgtcctg cgctcgggcc gcgaggtgct
    11821 gcggctggcc tcggtcgtcc gggtggaccg tacctggagc gaggcggagc tggcccgggc
    11881 ccagcaccac accgacgatc cgaggatcag ggccgccgtc aacggcgccc ggaccggcag
    11941 ccgaggtgtg gccgagtacc tggccgcggc gccccagttg ctcgacgact ttcgcaacgc
    12001 ctgggcggca ggcgcccgtc cgcgcgccgc cgccctggtg gccggggccg tggacgcgcg
    12061 gcgcgccggt caccacgagc cgctgcccga ggacgtcctg cgccgcctgc acgagatcca
    12121 cctcgacctg cgcggcggcg gcagcctgcg gccggagccg tgggaggagg cgctgaactg
    12181 ggccaccgac cccctgcacg ccacctccag cctgctgctg ccccgggacg acggcgcgta
    12241 cctcgccttc gactacctgc accagacact ggacgagcag gtgccgccgc cgcgcatccc
    12301 ggacgccgtg tgggagatcc tcatcgacca cgccgacccg gtgcgtgccc tggacatcgg
    12361 cgcgaccgcc taccagcgcg gcgacctgcg ccacgcgatg gccgccttcg acaaggccgg
    12421 agccgatccc gggcagctgc cccggcagtg gtacgccacg tgcgtggggg aggcgggcga
    12481 cccgcggcgt gccgcggacc tctaccacga cctggtcgcg gaggccgagc ggcgcggcgg
    12541 gcccgacgcc aaggagacac tggagaaccg caactcccac gcccgttacc ggggcatggc
    12601 cggccacccc gcggaggccg tcgacctgct gcgcggcgtc atcgaggacc gcacgcgcat
    12661 cctcggccgc gagcactccc acaccctcaa cagccgcaac aacctcgccc tgttcctcgg
    12721 cgagagcggc cgcctggatg aggcggtcgc cgtgtaccag tccgtgctgg ccgaccggac
    12781 ccgcctgctg ggcgccgacc acccgcacac tctcagcagc cgctacgggt acgcctacct
    12841 gctcggcgac gccggccgcc ccggacaggc cgcccggctc ttcgacagcc tggtcgcgga
    12901 ccgcacccgc acccagggcc cgtaccaccc ctacaccctc aacaaccgcc gccaccatgc
    12961 ccacttcctc ggcgaggcgg gccacgccgc ccgggccgcc gggctcttcg aggaactcct
    13021 ggaggactgc ctgaaggtcc tcgacccgct ccacccggac accctcgcct cccgccacgg
    13081 ccaggcccgc ttcctgggcg aggccggcga ccccggccgc gcggcggcgc tgctcgacgg
    13141 cctgatcgcg gacggccgca gagccgccgt gcacgggccg gacagcccga tcccgctgct
    13201 gtggcgccgt taccaggccg tcttcctcag cgaggccggg gcgacggagg aagccgtacg
    13261 gctgctggac acgttgctga ccgagagcgg cgggatcctc gacgccggtc acccccagct
    13321 gttcgcggtc cgcgccgccc acgcccgctg cgtcctgcgt gcgggccgca cgggcgaggc
    13381 tgccgcgctg tacggacggc tcgtcgacga ctgccgcgac cgtctgggcg aggaccaccc
    13441 ccagacgctc accgcccggg gcggccgcgc ccgctgcctg gccgcggccg gccgccacgg
    13501 ggaggcggcg gacctgctgg agatcctcgt ccaggaccgc acccgcgtcc tcggcgacga
    13561 ccatccctcc accctcaaca gccgcaacgc ccacgcctgt tcggtcggcg cggcgggcga
    13621 ctccgcacgc gccggccggc tgctgcgcca ggtcctccag gaccgggtgc gccatctcgg
    13681 cgaggagcac ccctggggcg accgcacccg ggacgagctg gcccgtttca cctgaccggg
    13741 cccggccccc ccgccccgcc tcgcgcccgg cgcgcggtca gccgcgggtg acgtgcccgt
    13801 cgaccagccg ccacagcccc agcgggttgt ccggggccag cgcctcgggg agcagcgcgt
    13861 ccgggaaacc ctggtaggtg acgggtcgca ggaagcgctc gatcgcgctc atgccgacgg
    13921 aggtgaaacg gctgtcggtg gtggccggga acgggccgcc gtggatggtg gcgtggccga
    13981 cctcctgcgg gtgggcgaag gcgttcacca cgatccgtcc ggtgcggcgc tccaggacgg
    14041 gcagcaggcg ggcggcctgc gggtggtccg cgtcatcgag gtgcatcgtc gccgacaact
    14101 ggccgcggaa gctccgggcc atctccgtca tctgctccac gccggtcagc cggacgagca
    14161 gcgcggccgg cccgaagacc tcgtcggcca gcgtgggttc ggccaggaac cggtcgccgt
    14221 cgacctcgag gagctgggcg cggccctcga aggcgccctc gggctccggt ccggccgcga
    14281 cggtcgcggc acccgcgccg cgcaggcgct gcgccccccg gccgtaggcg tcgtggatgc
    14341 cgggggtgag catcgtccgg gcgcccatcg cgctcacccg tgccgcggcc gcctcgcgca
    14401 tcgcggcgta ccccgggccg tctacggcga gcagcacggc cggcttcagg caggcctggc
    14461 cgacgttgac gagcatgcgc tcggcgaaac cgtcgccgat ctcgccaccg cgcgcggcca
    14521 gcgcggccgg caggacgaag gtcgggttga cgctcgtcat ctcggcgaag accgggatcg
    14581 ggtcggggcg cagctgcgcc cgccggtaca gggccatgcc gccgccctcg gagccggtga
    14641 aggtgaccgc cttgaccagc gggtggtcca ccagggcctc gccgatcgcg ttgccgggtc
    14701 cccggagcat cgagaacacg ccctcgtgca gcccggagtc ggccacggcg ccctggatga
    14761 cccgcccctg cagctccgag gcgccggggt gggcgttgtg ggccttgagg atcaccgggc
    14821 agcccgccgc gagcgcggcg gcggtgtcgc cgcccgcgac cgagtaggag atcgggaagt
    14881 tgctggcgcc gaacacggcc accggtccga tcgcgatctt ctgcatgcgg tggtccatgc
    14941 gcggcctcgg ctgccgctcc ggctgggccg gatcgacggc ggcctgccgg aaccggccct
    15001 gccggacgac ctcggcgaac tgccggaact gcccggcgga cttgaccgcc tcggcctcca
    15061 gctgcgcgac cgggagaccc gtctccaggg ccgcccgctc ggccagttcg cccttgatcg
    15121 cctccagccg gtccgcgatc agctccagga acgcggcgcg ctccgcgagg ccggtgcggt
    15181 tgtaggtgtc gtaggcctcg tcggccagcc gcgcggcgcg gtccacctcg gcggcaccgc
    15241 cgagtgcgaa ctccggcccg accggctcgc cggtcgccgg gtcgagtgcc ttcatcgtgc
    15301 cttcggacgc ggggacggac gacgcgccta tcagtatctc tccggtcagt cgcatgtcag
    15361 tggtctccgt tctccagcgt gctcagcagg tcggcggtgg tggtgatgga gtgggcgtac
    15421 gtggggccgt tgagctcgtg ggcggcgtgc atcatctcgg ggcggtaggc cgcggtggcg
    15481 tcgcggacga gcgtcacgtg gtatccgagc tccatggcgt agcggccggt ggactcgatg
    15541 caggtgttgg cgagcagccc gatgacgatc acatgcgtga tgccctgctg cttgagccgg
    15601 aagtccaggt cggtgttggc gaacccgctc tgcgaccagt gctcctggat gaccacgtcc
    15661 ccgtcggcgg gacggaagtc ggggtggaac tcgccgcccc aggtgccgaa ggcgaaggtg
    15721 cgccgctcct ggatgatgcg gtgcgtcggg ttggggtgct cccagtcctc gtagtcgccc
    15781 tcctgccagc ggcggtgggg gacgaagaag accttctgcc ccgccgcgcg cccggccccg
    15841 acgacggcgc ggaggttgtc gagcagaccc acctcggtgg ctacgggctc cagcgcgggc
    15901 cagacctttc cgccctcgga gaggaagtcg ttgtaggggt cgaccagcag gatcgccgtc
    15961 cgcgtggggt cgtaggtgtc ggtcatgacg cgtcctttcc cattctggat tatttgcatc
    16021 atcctcattc aggattactc tcgtcatcct gaaagtcaag gaacgaatgc gaggtgggga
    16081 catggccccc gatgaactgc gcgaagccct gatcggcgcc tggcgcctgg tgtcctacgc
    16141 ggccaccgac gtcgccaccg gcgaggtcgt cgagcccttc gggccgcggc cccgtgggct
    16201 gatcacctac ggccccgacg gccacatgtc ggcccagatc atgagggccg ggcggccgga
    16261 cttccgccac gggcggctcg aggaggggct gcccggggaa ctggccgcgg cggccgcggg
    16321 ctatctcgcg tacgcgggca ctttcgaggt cccggcggag gacacggtcg tgcaccgggt
    16381 cgaactgagc ctgttcccca actgggttgg cggtgcgcag acgcggatcg ccgcactgga
    16441 cggccgcagg ctccggctga gcctgcccgg cgccgccagg atctggggcg cgctccgcac
    16501 cggcgtcctg acctgggagc gcgccgggcg gtagcggccg ccgtgctccg cgggggctac
    16561 ccgcgtacgg cgggagtggc ggcggcggtg gcggtggcgg tgtcggtacg gccgggtccg
    16621 gtgccgtcgc cccgccgggc ggccctcccg ctgccgccgt tccgggcgcg caggccgtgc
    16681 caggcgagcg tcaggcccgc gaggatcagg aagccgaggc cgcccgccac cacgccgtgc
    16741 cagccggagg ccgagaagag cactcccgcc acggccgaac cgacggcgcc gccgccgaag
    16801 acggcgaaca tgtacaccgt gttgaggcga ccccggatgc ccggcgccgc ggtgaagatg
    16861 cgggcctggt tggctatctg gccgctggtc accccgtaac cgaggaggtt gcagccgacg
    16921 gcgaggacga cgagcgaccg ccccgcgacc ccgaagagcg cgaaggccgc caccgccgcg
    16981 atgacggaga gggtgttgac cgccagcggc ccccaccggt cggtgagccg gcccgagtag
    17041 cgggcggcca gtgcgcccgg cacgctgcac aggccgaaga ggccgaccac ggccgggccc
    17101 agcccgatcg gcggcgcggt gaggtggaag gcgagcgtgg accagaaggc ggagaaggag
    17161 gcgaagaccg tcgcccccag cgcggccgac aggcgcaagg gggcgtggtc caccagcagt
    17221 cgggggagcg aggccagcag ccgtccgtaa ccccccgagg cctcggctcc ggcgggccgc
    17281 ccggccggca tgtagcgggg aaggatcagc agcagcgccg ccgtggccgc cgcggcgacc
    17341 aggaagcccg cccgccaggt gcccgcggcc tgggcgatga gcccggaggc ggtgcgcgag
    17401 agcagggcgc ccatcgtcag ccccgtgccg accgccccca ggacccgccc ggcctggccg
    17461 ggcgcggcca tggacgcgac cgtcggcatg atcacctgcg ggagcacggt gctcgccgag
    17521 aggacgaggg tcgccatgcc cagcagcgcg acggacggcg ccgcggcccc ggccagcagt
    17581 gcgacggcgg tcaccgccag cagcactctg gacagccggc gcagccgggc ccggtccgcg
    17641 agcggtacga cggccacgat gcccagcgcg tagccgatct gccccgccgt ggccacgagc
    17701 ccggcggcgg aggcggagat gccgaagccg cgggcgatct ggtcgaggag gggctgggtg
    17761 aagtagatgt tggcgaccgt gatcgccgtc gccgtggcga agacggggag ggttccccgc
    17821 ttgacgtccg gccgggttgc tgcggtggtc atgggtcctc gcggaggggt cgcgggcggt
    17881 ggggcggtgg ggcggtgggg gtgcggcgcc gggcccgctg cggtgggggc ccgagtgccg
    17941 ggaagtgtgg atgattggag tcatcctgat atgcaggatg atgcgtgtca tccttcatgt
    18001 caaaggcccg gggaagggtc cccgggaagg tgtatgatgt ccgtcatcca cataggtcgg
    18061 cacggtccga cgcacatccg ggaggtcagg cgatgggtca ctcgcaggca gcgaaggccg
    18121 agtcgcgcga gaaggtcctg cggatcgcgg cccgccggat ccgcgaggag ggcatgaccc
    18181 gccccggcgt cgccgacctc atgaaggagg ccgggctgac ccacggcggg ttctacaagc
    18241 acttctcgtc gcgcgaggac ctgatgggcc aggcggcggc gctggcgctg gccgacggcg
    18301 agggcaagat ggccgacgcc gcccgcaggg accccgtggc gccccgctcg gggctgatcg
    18361 acgcctacct cagcgcccgc caccgggacg ctcccggtac cggctgcgcc ctggtgaccc
    18421 tcggcgccac ggccggccgc ggcgacgagg cgctgaagga ggcgtacgag cagcaggtcc
    18481 gcaagtacct cgaactcatc ggcgaggccg cacagggcgg tgaccccgag gtggcgcagg
    18541 ccgacgcgat ggtcaccctc agcgccctcg tcggcgcgat gctgatctcg cgcgcggtcg
    18601 ccgaccccgg gttctccgac gagatcctgg cgacggtcgc cggacggctg aaggacgccg
    18661 acacgcacgt gcccgcggag gtctgaccgc atccccggaa ctcccgccgc gcgccccgag
    18721 gccccttgag gcacccgtag gcgcgggcgg cgtgcgcggc ctgagcggtg gaggaatgaa
    18781 ccctttcatc gccttgtacg gtggttagcg tacgagtacc gggaagccgc gagggcggac
    18841 catggcgaca cggatcccct ccctggtcgg caggcaggcc gagaccgagg cgatcgaggc
    18901 tcttctgcgc cctgcggacg gccgcggcgg cgccctggtc ctgcggggcg acgtggggat
    18961 cggcaagacg gcgctgctgg ccctcgcccg ggaacgggcg gcggaacagg ggcggcgggt
    19021 gctcgccctg gccggtgtgc aggccgagtc ccacctgccg ttcgccgggc tccaccaatt
    19081 gctgcgcccg gtgctccagg agaccggccg cctcacacaa gcccggcgcg agacgctgct
    19141 ggccgccgtc ggcctccacg acgccggccg ccccgagccc ttccgtatcg ccctcgccgt
    19201 gctcgacctc ctcacggagt gcgcctccgg ccgaccgctg ctgctgctcg tcgacgacgt
    19261 ccagtggctc gaccggtcca ccagcgacct gctcgccttc gtcgcccgcc ggctctcctc
    19321 ggaccccgtg gtgctgctcg ccgccgccac ccggggcgag acgcaggcgc cggtctggga
    19381 gggcgtcgag gaactgccgg tgagccggct cgacgccgac cacgccgcgc ggctgctgga
    19441 cgccggcgcc cccgcactcg cgcccttcgt ccgcgcacgg ctgctggagg aggccgacgg
    19501 caacccactg gccctcgtcg aactgcccct ggcggccgag ggcctggaat ccgtcgcggt
    19561 catcccgcgc tggctgccgc tgaccgccaa cctgcagcgc gcgttcgaga cccggatccc
    19621 gggcctcccc gacgccaccc gcaccctgct gctggccgcc gcgctcgacg ccgaggctgc
    19681 gaccggcgac gtcctgagcg ccgccggcgc cgtgaccggc ggccccgtca ccgtcgacgg
    19741 cctcgtaccc gccgtggagg ccggactcgt ccgcgtcgac cgggacgccg tgcgtttccg
    19801 gcatccgctg gtccggtcgg cgatccacca ggccgcgtcc gtcacgcagc gcaccgccgt
    19861 ccacgccgcg ctcgccgcgg ttcactccgg ccgtcccgac agcggcatct ggcacctggc
    19921 cgcctccacc gtccccccgg acaaggccgt cgccgagggt ctgcagcggt gcggggagcg
    19981 tgcgctgcgg cggggcgccg tcgtcgcggc cgtgcacgcg ttcgagcagg ccgccgcctt
    20041 cgccccggac gggcgccggc aggccgacct catgctgcgc agcgcggagc tggccgtcgg
    20101 cctcggccgc cgtgacctcg tccgccgcct ggtgcgcacc accgagcggc tggagccgac
    20161 cgccaaggac acggcccgtc tgctgtggat ctcggagtcc ctgaccgtct gcgggggccg
    20221 ggagccggtc gccgtacgga cgctgctccg cgcggccgaa cgcatgcgcg ccgacggcga
    20281 gacggccctg tcggtccggc tcacgggtgc cgcggccgcc catctctacc gcggcaacgg
    20341 ggagtccgcg ctccacgcgg aggtcctgcg caccgccgac cggctggccg ccgaaccgga
    20401 cggccggtgc gacaccacgg gcgcggccat gctgctgatc gccgcgcacg ccgcccccgt
    20461 ggagcgcgcc gcctcggtgc tcgaagccgc ccgcgccctg gcccaccgca cggacgacgc
    20521 cgcggcgctg cacacgacgg cccgcgcgct ctggtgcgtc ggagcgcccg aacgcgcgga
    20581 ccccttcctc accgcggccg tcgaacggct ccgccaccag gggcggctgg caccgctcgc
    20641 ggaggcgctg gccctgcgcg cctcgggacg cgcggccacg ggccggtgcg acccggcgcg
    20701 cgtcgacgcc gacgaggcgc gccggctcgc ccgtgagacc ggccagcccg aatgggaggc
    20761 caccgcgctc accgtgctgg gctgcgtcgc cgccctgcgc gacgacgcgg cgaccgccca
    20821 ccggctgatc gggcacgccc gggccatcgc cgtccggcag aactcccccc tgctgcacgc
    20881 gacggtgcgc atggcgcgcg gcacggcgct gtcctgcagc ggggaccacg ccgaggcgta
    20941 cgcccagttg cggtggctga cagaccccgc cgacccgggg caccacatga tgaccgcgct
    21001 gtggaccgtg ggcgacctcg ccgaag
//
