LOCUS       NZ_FWXV01000018        22521 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Kibdelosporangium aridum strain DSM 43828, whole genome shotgun
            sequence.
ACCESSION   NZ_FWXV01000018
VERSION     NZ_FWXV01000018.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium aridum
  ORGANISM  Kibdelosporangium aridum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900176515.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:02:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,283
            CDSs (total)                      :: 11,193
            Genes (coding)                    :: 11,032
            CDSs (with protein)               :: 11,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 3, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 38 of 161
            Pseudo Genes (incomplete)         :: 135 of 161
            Pseudo Genes (internal stop)      :: 6 of 161
            Pseudo Genes (multiple problems)  :: 17 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:58:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 89921
            Orig. end                         :: 112442
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FWXV01000018.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22521
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22521
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22521
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12521](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12521)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(372..385)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.95"
                     /tool="antismash"
     gene            complement(382..1383)
                     /locus_tag="B9C43_RS51685"
                     /old_locus_tag="SAMN05661093_10543"
     CDS             complement(382..1383)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646284.1"
                     /locus_tag="B9C43_RS51685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10543"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_084434594.1"
                     /transl_table=11
                     /translation="MRPIRSACLAILLLSASVACTGEPGAAGTTTKVSYLTSFSTFGRD
                     AYAYVAQDKGFFTEAGLDVTINPGSGTVDVLKLVAGGRAHFGVADATGTMITLAKEKLP
                     VIAVAAVQQRTVAAIIGLEGGRIATPADLIGKKVADPPGSTVKLMFPLYAKAAGIDAGK
                     VEFVPSAPPALPQLLVSGQVDAIGQFVVGKPLIEAAAAGRKAVVLPYGDLLPDLYGNML
                     VTTKDLADRDPELVRRFSGALLKGLRYSIEHPDEAGQILRKYQPTQNSDVASAEMRLMT
                     GYSRPDGFSGPLGAVDEGRIGTIIQLLEQAQAIPAGSLRPADLVNFGLVPKS"
     gene            complement(1609..3000)
                     /locus_tag="B9C43_RS51690"
                     /old_locus_tag="SAMN05661093_10544"
     CDS             complement(1609..3000)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="B9C43_RS51690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10544"
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="WP_084434595.1"
                     /transl_table=11
                     /translation="MTSRKWRLSTRLRVALTAAAGSAVVLVVGTAWFIGQLQDEADAKV
                     FEIAQQKAHAVAVTLETANDVPGRLPELGSLGPWEVVDKDTGRRVASFPPACTAHPDVP
                     FLAMLAKESPPYRVTLPQTAPGDIAANCYTAGTYPLDRDLQVAQVTINDSEYTVYAGER
                     LDAGTHEPVATARATAWTTVPIGVVLIAVVAWLSVRRALRPVNAIRFEVADITSEGLRR
                     RVPVPRTGDELSLLAETMNDMLTRLDRSTQRQRQFVADSSHELRGPLATLRTRLEVLLT
                     YPDRMNWQEVCTKSMSDVERLQSLVSDLMLLARLEDKHANTRQLVDLSALVADEAADRP
                     VITDVRSSVTVQGNPTHLRRMLRNLLDNAERHAASRTTVTLAVSTGQAVLTVTDDGAGI
                     PEPDRERVFDRFVRLDEARTRDRGGSGLGLAIAREIAREHGGTLKIAPSDVGAVLVATI
                     PQAGQ"
     misc_feature    complement(2206..2208)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2997..3671)
                     /locus_tag="B9C43_RS51695"
                     /old_locus_tag="SAMN05661093_10545"
     CDS             complement(2997..3671)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020634541.1"
                     /locus_tag="B9C43_RS51695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10545"
                     /product="response regulator transcription factor"
                     /protein_id="WP_084434614.1"
                     /transl_table=11
                     /translation="MRVLVVEDETGLAETLKAGLTAEGYAVDLAFDGADGLWLASRYRY
                     AAVVLDIMLPGLNGYQVCQRLRATDNDTPILVLTSKDGEYDQIEALDTGADDFLVKPFS
                     YQVLLARLRALVRRGGSSSPSVLRLDDLSLDLGTRRCRRGEVDIPLTPKETAILAYLLE
                     RAGEVVSKADLVANLWDFAAEVDPNLVEVHISALRGKIDAPFGRRTIKTIRGAGYQLTG
                     QR"
     misc_feature    complement(3474..3476)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    3623..3637
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
     gene            3780..5324
                     /locus_tag="B9C43_RS51700"
                     /old_locus_tag="SAMN05661093_10546"
     CDS             3780..5324
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021379.5"
                     /locus_tag="B9C43_RS51700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10546"
                     /product="DUF2079 domain-containing protein"
                     /protein_id="WP_160097343.1"
                     /transl_table=11
                     /translation="MPIPQWLTRDPLPRALAAAASASYATHSIRLHRSFQSSGYDLGIF
                     EQIVKSYADGRWPTADLLGPGAPALADHFHPILVVLAPFYLLFPYPETLLVAQSCLFAV
                     SVVPVTRLALRVHGKPVGSVIGIGYAMSWGLWSAVDFDFHEICFAVPLVALAVERLATQ
                     QWKAAAAYALPLLLVKEELALTVMGIGLYLIWRKQRPVGLALTIFSVTSFILVIVVIMP
                     ALSTDASYHQIRSLTAPIATPIVAGWDTKLVTVLALLAPTAFVALRSPTVALAIPTLGW
                     RFASGTPTHWGIYAHYSAVLMPIVFVAFVDGLRRLQETRRSIPCAAVVTCLVVTSLTTV
                     MLAIRAPGKPRWTADQQAAARHALTLVPDGVTVAASNRLAPQLTNRCRVMLYRSEQSTR
                     SQWIVLDRQADTPPTTGYVVIAELPHLAIFTMSASGHTPTGSVWWTKPQVALRKPGTAT
                     TPLTGSSPLPGRTRSQARSTTATARRSSTPRAPASRHWPGTVPTATPQHASPAPTR"
     gene            6068..6178
                     /locus_tag="B9C43_RS59240"
     CDS             6068..6178
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025563.5"
                     /locus_tag="B9C43_RS59240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_235039340.1"
                     /transl_table=11
                     /translation="MATGRLLDVAGQSTADGAKVSTWTPTSGPNQRWAVT"
     gene            complement(6175..6315)
                     /locus_tag="B9C43_RS57255"
                     /old_locus_tag="SAMN05661093_10549"
     CDS             complement(6175..6315)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS57255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_10549"
                     /product="hypothetical protein"
                     /protein_id="WP_160097345.1"
                     /transl_table=11
                     /translation="MASRMSPQWLDDDTDPTGGHLDLPSNALAREQFRCLFGDWRLVPP
                     F"
     gene            complement(6396..7268)
                     /locus_tag="B9C43_RS51710"
                     /old_locus_tag="SAMN05661093_10550"
     CDS             complement(6396..7268)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098589.1"
                     /locus_tag="B9C43_RS51710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10550"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_084434597.1"
                     /transl_table=11
                     /translation="MTILVTGATGLVGRHVVGQLVQAGESVRALTRNPAKARLPEGVEV
                     FQGDLLEPASVVPAFEGVQKLFLFPQPETAAEVVDLAKQAGVRRIVVLSAAAVTLGFDT
                     GYHVRVERAVEESGLEWTHVRPGEFMTNMLPIWGPMIKESRTVRYPFGDDLGSAPIHEA
                     DIATVAVALLEDKHVGKAYTLSGPEQLTVRGQVQAIADALNETVHYEEVTREEARDILK
                     AMGGFAAESADLQLGFVDYDGGEGSGDQGYSDQDYSDLMKPLPDFGLATGKTGRTYAEW
                     ARDHVDDFR"
     gene            complement(7415..9166)
                     /locus_tag="B9C43_RS51715"
                     /old_locus_tag="SAMN05661093_10551"
     CDS             complement(7415..9166)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005464188.1"
                     /locus_tag="B9C43_RS51715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10551"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_235039335.1"
                     /transl_table=11
                     /translation="MDDGKPGSAWRLLLGHARPYRRTLLVAAVISCVGGLAGLAQPLAA
                     KAVIDALSANEPVLTPIILLTGLVVGAAVIAAIGTYLLERAAEGVVLVARRGLVHRLLR
                     LPVAEFDRLKPGDLLSRVTSDTTLLRTAATSTIVEAANGTLMILGTIVLMALLDPVLLG
                     VTLAVILVTVVLTGSVVPRIGRASERAQQAVGEMGAVLERALGAFRTVKASGAEERENA
                     VLDQAADRAWRQGVSVAVWSSMVGILARLSVHVSFLAVLGVGGARVADGTLPLSALIAF
                     LLYVFYMITPIAALVNAASDLQAGLAAVRRTRQVHILPTEPAAQGAPATVTATGPASVA
                     FHSVSFGYPGNRESVLTDISFQTPPGGMTAFVGPSGAGKSTIFALLERFYEPAAGSILL
                     DGRDVRDWPLAELRAAIGYVEQDAPVLAATLRDNLRLAAPHASDEDIHDVIVRTRLDDL
                     LPRLPDGLDTMLGHRGLTLSGGQRQRIAIARALLRRPRLLLLDEATSQLDAVNEHQLRQ
                     VVAELARSTTVLVAAHRLSTVTSADRILVLDAGRLRANGTHTHLISTDALYRQLAATQL
                     LTTQPQP"
     gene            complement(9175..9972)
                     /locus_tag="B9C43_RS51720"
                     /old_locus_tag="SAMN05661093_10552"
     CDS             complement(9175..9972)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667226.1"
                     /locus_tag="B9C43_RS51720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10552"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_084434599.1"
                     /transl_table=11
                     /translation="MTQTEQSWQWYDDNAGIYEELDPATLEFGRLLLDYADPVPGARLL
                     DVGAGRGAVVRAALARGCLVTAGDAAPGMVARLRADFPTVAVSMLDAHRLAFPDACFDM
                     VTAGFVIDLLSDPAVAVAEVRRVLRPGGVFALSVPGPLPHRGRWQWLVDLAQEFFPATV
                     AEDRDGQTDVDVTGLLAAAGFTGLTRKDFEHPEPVSDPAALWDLFASRLPAAVSSGSVE
                     WLPPDRAAEFHRRFLTGAEQMHANGGIAFDRHLTMYRALAPAA"
     misc_feature    complement(9877..9879)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9989..10003
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            complement(10001..10417)
                     /locus_tag="B9C43_RS51725"
                     /old_locus_tag="SAMN05661093_10553"
     CDS             complement(10001..10417)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007031547.1"
                     /locus_tag="B9C43_RS51725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10553"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_084434600.1"
                     /sec_met_domain="PF13471 (E-value: 8.7e-27, bitscore: 86.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPESISYDPRSVSFGRRIRVRAMVAAARLLATRSPQRIRKVLA
                     WLHRDVRPATYEETCDARQAVVSVSLACAGREGCLLRSLATILLCRSYGHWPTWCLGAR
                     RLAPFYAHAWVEVDGVMVGEDYPDGYFRTFFTVP"
     gene            complement(10427..10684)
                     /locus_tag="B9C43_RS51730"
                     /old_locus_tag="SAMN05661093_10554"
     CDS             complement(10427..10684)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670106.1"
                     /locus_tag="B9C43_RS51730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10554"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_084434601.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 3.6e-25,
                     bitscore: 80.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.9e-17, bitscore: 54.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLRPGVFDAETEYGIVLLDGDSGEYYDLNGTGALVLRTLMAG
                     GTAGQAAQALTEEYGVSLDDATRDVRDLLADLRSARLVEQ"
     aSDomain        complement(10433..10681)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B9C43_RS51730_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.10E-25"
                     /identifier="RREFam002.1"
                     /label="B9C43_RS51730"
                     /locus_tag="B9C43_RS51730"
                     /protein_end="84"
                     /protein_start="1"
                     /score="80.5"
                     /tool="antismash"
                     /translation="ALKLRPGVFDAETEYGIVLLDGDSGEYYDLNGTGALVLRTLMAGG
                     TAGQAAQALTEEYGVSLDDATRDVRDLLADLRSARLVE"
     gene            complement(10695..12521)
                     /locus_tag="B9C43_RS51735"
                     /old_locus_tag="SAMN05661093_10555"
     CDS             complement(10695..12521)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="B9C43_RS51735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10555"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_084434602.1"
                     /sec_met_domain="Asn_synthase (E-value: 6.5e-30, bitscore:
                     97.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYARLDHVPSWFVVLPDCRAAEPVAAALRSQATCVTRHPSGRTW
                     LVGRWAQEEITVAESRGTAIAVIGEHLLSAAFLTRVAGRVGTLADLDEPSSSWAGNFHL
                     IASVAGQVRVQSPISGFRRVLHASVDGVTVAANRADVLAGLTGAALDEARLTVALLEPC
                     APHPIGGQPMWRGLAAVPAGSYLTIDGAGRHRHVRWWTAPEPTVPMAEGAPALRAALSG
                     AVEVRTRGHDLISTDLGGFDTTSLCCLAARGPAHVAAYTWAPPDPLADDVFWARRTVAA
                     LDTIEHHVVPSECAPFAFSGIGEQDDVALDEPCAVTLDRRWLVIADRAAARGSTTHLTG
                     FGGDQVLGGSPAHLHTMLRRQPRIALRNLRGYAALNRWPYRMALRQLLNSESYQAWLLR
                     FGAELTAGPLSSLGPSFYWAKPVRLPPWTTPDAVAAVRDLIRSAAPAAEPLGHGHGQHQ
                     ELADLGGVARMVRNLGELARQRGVRLAAPYFDDRVIEAGLAVRPQERVTPWRFKPLAVE
                     AMRGIVPDETLTRQTKAIGAHEVEVGLRENRADMLALCDNSRLGKLGLIDEDALREVCA
                     RPLPTAVEFSALYPTLACEIWLRALERHTVPR"
     gene            complement(12648..12758)
                     /locus_tag="B9C43_RS59245"
     CDS             complement(12648..12758)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039305.4"
                     /locus_tag="B9C43_RS59245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_235039336.1"
                     /transl_table=11
                     /translation="MRTYERPTLRASGSFTKKTGVGSHGPADLIVLSHKN"
     misc_feature    complement(12805..12820)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
     misc_feature    12951..12961
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    13100..13115
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.83"
                     /tool="antismash"
     gene            complement(13207..13896)
                     /locus_tag="B9C43_RS51740"
                     /old_locus_tag="SAMN05661093_10556"
     CDS             complement(13207..13896)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020669502.1"
                     /locus_tag="B9C43_RS51740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10556"
                     /product="response regulator transcription factor"
                     /protein_id="WP_033391886.1"
                     /transl_table=11
                     /translation="MNTSGASNDGAPIKVLLVDDEQLVRSGFRLLLDVEDDITVVGEAT
                     NGAEAVEQARAARPDVVLMDIRMPKMDGIQATREIAATKGLQQVRILILTTYDTDAYVF
                     EGLQAGAGGFMLKDAGPAELLHGIRVVAAGDSLLAPRITRRLIAQFTAQRTANKAAEHR
                     LAVLTEREREVLALVGQGMSNDEIGAELFLSPATARTHVSHAMVKLGARDRAQLVVIAY
                     QTGLVTP"
     gene            complement(13893..15125)
                     /locus_tag="B9C43_RS51745"
                     /old_locus_tag="SAMN05661093_10557"
     CDS             complement(13893..15125)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="B9C43_RS51745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10557"
                     /product="sensor histidine kinase"
                     /protein_id="WP_084434603.1"
                     /transl_table=11
                     /translation="MQVRVMLFRLPAWAQDVLLALFITVMQVQGTIVRNSGEPELVLRP
                     LADLGYLGYILLVVSGAAVAVRRRWPVAVFAATALASVVYYALDFPDGPGWLGLFVAIY
                     TLTALGDGRRSLVTAGVGIAAMAACWLLAAADIQPPAAIGWVFFRIGASVMSAALGESV
                     RSRKFIAAEALERAELAERTREEEARARVDEERLRIAREVHDTVAHAIAIINVQAGVTA
                     HVLDKRPERARETLEAIEKTSSHALQEMRSILGVLRDDNDGRVPHPGLGQIDDLTAKAR
                     EAGLDVDLVASSPPSPVPSAVGSAVYRILQESITNVIRHVGPTRVTVGLEYGADTVEIR
                     VRDEGRREPAGRDEAAPHPDDGWDKPGRGILGMRERCQLLGGELDAGPLPGGGFAVTAR
                     LPLAPTGTANV"
     gene            15295..15645
                     /locus_tag="B9C43_RS51750"
                     /old_locus_tag="SAMN05661093_10558"
     CDS             15295..15645
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039381.4"
                     /locus_tag="B9C43_RS51750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10558"
                     /product="DUF6223 family protein"
                     /protein_id="WP_084434615.1"
                     /transl_table=11
                     /translation="MSALHLLASEVSITAAGYELGVGRTVPTVAALLGLTSVIFGGLAL
                     ARSRRTGMIVALVLGPISMIVGGVHGANAAGGLGTGNGLAGAIFAVVLGLIGVVLGGLS
                     LARSRRTGRSVR"
     misc_feature    15699..15714
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
     misc_feature    15734..15748
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            15776..17371
                     /locus_tag="B9C43_RS51755"
                     /old_locus_tag="SAMN05661093_10559"
     CDS             15776..17371
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005157518.1"
                     /locus_tag="B9C43_RS51755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10559"
                     /product="flavin monoamine oxidase family protein"
                     /protein_id="WP_084434604.1"
                     /sec_met_domain="DAO (E-value: 6.6e-10, bitscore: 31.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPDVTRRALLRSIGVAGGAGVMFESMRALGLVASPEALATPAYQ
                     PPATGDLTVAKRGKKVVILGAGIAGLVTAYELGKAGYDCTILEANDRVGGRNWTVRGGT
                     TMTDLDANTQTAKFAHGQYLNAGPARLPQSHITLDYCRELGVPVETFINQNANALLYNE
                     QSGVAAQQYRTAKADFYGYISELLAKAVDHGSLDQSLSGEDKDRLLTFLSGFGAIGDRA
                     DGFAYTGTSRRGYSVEPGAAEQAGVVLGPPPSLSTVLASQVGRYFSFEFGYDQAMTMLQ
                     PVGGMDAIPMALYRAIGRHKVRLGAAVTKVTDLAHGVEVVYKDARGKEVLVRADFCVAA
                     LPPHVMARIPTNLDAGVTAALRYPTATPSGKIGLEYRRRWWEQDDRIYGGITETDLDLA
                     HIWYPSYGFHGERGVVVGYYNTGANATAYGSLSHVERTKRAVAQGVKIHGKKYSDELVS
                     SFSVAWQRVRHIEGAWVSWPSRTSGEYALLNKPAGRVYFAGDWLSYFIAWQAGAIDSAR
                     YVVTNIHQRVMAER"
     misc_feature    16685..16687
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17376..18032
                     /locus_tag="B9C43_RS51760"
                     /old_locus_tag="SAMN05661093_10560"
     CDS             17376..18032
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013228.5"
                     /locus_tag="B9C43_RS51760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10560"
                     /product="Rid family hydrolase"
                     /protein_id="WP_033391892.1"
                     /transl_table=11
                     /translation="MNRFSRRRLGIVAGGTAAALGVGTTDAAASGGRKAPRPTEVRFNL
                     PPGGTNPSIANGVAVGSMVAVYTSSGLGPAAANPSAPAGSPEQYVDLSLFPGGKLPAGV
                     TVTEAQAWNTLTRIVDNLTTVGLRPRDVITMKCYLKRPAGASDADYAGWNRAYRQFFAN
                     VDLGTGAPIPVPTGTGAAAPAKILNPARPARATLEVAGLAVPGWLIEVEVQATYH"
     gene            18077..18460
                     /locus_tag="B9C43_RS51765"
                     /old_locus_tag="SAMN05661093_10561"
     CDS             18077..18460
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS51765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_10561"
                     /product="hypothetical protein"
                     /protein_id="WP_084434605.1"
                     /transl_table=11
                     /translation="MDGRPDDATQILLAEYAALRAEAERRATVQWHVVALHPTRLAFQG
                     VAVLALVGALGAGIFLWITRSPSWYVIAGFAVGWLIDTLATVFLHRSIVRLTTAFIASR
                     EPTGTLRAVAASSGHDHCRKGRR"
     gene            complement(18465..19238)
                     /locus_tag="B9C43_RS51770"
                     /old_locus_tag="SAMN05661093_10562"
     CDS             complement(18465..19238)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225798.1"
                     /locus_tag="B9C43_RS51770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10562"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_084434606.1"
                     /transl_table=11
                     /translation="MSQLVDRTITALRSEHDTLAGLVRTLTDDQLAATSGAAEWTVAQV
                     LSHLGSGAEIGRAPIVRAAGETVTAEDNQTIWARWDASAPRAQAEGFLEYDSRWLDTVE
                     ALTPEQRSSLTVDLGFLPEPVPLVTALGMRLNEVANHSWDVRVAFDAHAEVDADSAAVL
                     VDLLTGPVAFMLNFLAKPAELAAPVSVAVPGAGLVIDDAVTVVDHVESPSATFNGPPEA
                     FVRLISGRLKAPYDNGVTIDGNITLDDLRRVFPGF"
     gene            complement(19235..19732)
                     /locus_tag="B9C43_RS51775"
                     /old_locus_tag="SAMN05661093_10563"
     CDS             complement(19235..19732)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012334.5"
                     /locus_tag="B9C43_RS51775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10563"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_084434607.1"
                     /transl_table=11
                     /translation="MTWKPPPLAGRAYAVTGGNAGIGYFIAEQLAAAGADVVLMDRNAE
                     RVQVAADAIQSHTGKAVAATVEPSVTGTQSVFRALSIVHAFSARQPTLTGPEVEGLQST
                     VAVEPADAALLEPAFLLSACSIVWGDPRQVQFGTFTSTGRGRAGEALIGGTDASVPGLG
                     VA"
     gene            complement(19847..21127)
                     /locus_tag="B9C43_RS51780"
                     /old_locus_tag="SAMN05661093_10564"
     CDS             complement(19847..21127)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.5"
                     /locus_tag="B9C43_RS51780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10564"
                     /product="MFS transporter"
                     /protein_id="WP_084434608.1"
                     /transl_table=11
                     /translation="MAPRWETNAARETSLSPQAQVRLMEQHMPEAVHTTSPAVVRGGDR
                     LPGKALLGLFLTGFVGILTECLPAGLLPDMARSLHTSVALTGQTVTLYAAATSIAAIPL
                     TRAFSKWPRKNVLLVALAIVAVTNALTALSDNYTLTLVIRFVAGLGTAMIWPQLGGYAA
                     RLAPAGQQGRAITVALAGTPIGLALGIPLGTWLSTLGGWQAAFYSCAGLTVLTMLWALV
                     TLPNLPGLPVDQRRKVSDTLVIPGLRVILFAIAAYMIAHNILYTYVSDFLRHVGMEGRT
                     GLVLFVFGVTSVLSTLVVGMHIDRHLRKLVVASTVLFAISVLVLAVLSDAPALVYIAVG
                     AWGFAFGSSASLFIGAAINASREAADVAQSIVITVISGSIAAGGLVGGLLIAGLGAASI
                     TWAALALLVAATAAVTGGRKHAFPKNA"
     gene            complement(21183..21926)
                     /locus_tag="B9C43_RS51785"
                     /old_locus_tag="SAMN05661093_10565"
     CDS             complement(21183..21926)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (10-182). E-value: 2.6e-16.
                     Score: 52.0. Matches aSDomain:
                     nrpspksdomains_B9C43_RS51785_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005452433.1"
                     /locus_tag="B9C43_RS51785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10565"
                     /product="3-oxoacyl-ACP reductase family protein"
                     /protein_id="WP_084434609.1"
                     /sec_met_domain="adh_short (E-value: 8.2e-40, bitscore:
                     129.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.9e-31, bitscore:
                     101.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVPLADRRALVTGGSRGIGRAVVRRLAGDGAAVAFTYSASAAAA
                     EKLVAEVAETGGTAIALQADSGDPEQVTRSIDETVTQLGGLDILVNNAGILPAGPIESL
                     TMDQFDRLVAINIRGVFAAIQAALPHLGTTGRIINIGSINADRVPLAGMSIYAMSKAAV
                     AGLTRALARELGPRGITVNNLQVGPTATDMTPEDSEIAGTLRELMALGRFGQPQEIASA
                     VSYLAGPEAAFITGANWNVDGGFTV"
     aSDomain        complement(21381..21896)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS51785_PKS_KR.1"
                     /evalue="2.60E-16"
                     /label="B9C43_RS51785_PKS_KR.1"
                     /locus_tag="B9C43_RS51785"
                     /protein_end="182"
                     /protein_start="10"
                     /score="52.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVVRRLAGDGAAVAFTYSASAAAAEKLVAEVAET
                     GGTAIALQADSGDPEQVTRSIDETVTQLGGLDILVNNAGILPAGPIESLTMDQFDRLVA
                     INIRGVFAAIQAALPHLGTTGRIINIGSINADRVPLAGMSIYAMSKAAVAGLTRALARE
                     LGPRGITVN"
     CDS_motif       complement(21828..21896)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9C43_RS51785_0001"
                     /evalue="4.00E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="B9C43_RS51785"
                     /protein_end="33"
                     /protein_start="10"
                     /score="16.3"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVVRRLAGDGAA"
     misc_feature    21930..21944
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.82"
                     /tool="antismash"
ORIGIN
        1 gccacgttcg cgcaggccga ggcgaagttc cgcgcggcgc gcgcgtgggc catggaggtc
       61 tgggccgaca acgaggcgac gctggaccgc ggcgagaaac tgagcaccga gcaggagacc
      121 ctgacgcggt tgatgctcaa caacacgacc tggtccgtgc agtccgtcgg ccagaccgtg
      181 taccagtggg ccgccaccgc cgcgatgcgc cggggcgacc tgcagcggta ctaccgcgat
      241 ctcaacgcgg gcactcagca catcacgtcc ggtccggtgg tgctgcagaa ctgcggcaag
      301 tggttggccg gtctggctca gcacgcccgt tgggagttcc tggatctggt gtctggagag
      361 gactccggga cgcactgagc gtcacgactt gggcaccagc ccgaagttca caagatcggc
      421 gggccgcagc gatcctgccg ggatcgcctg tgcctgttcg agcaactgga tgatcgtgcc
      481 gatccggccc tcgtcgaccg cgccgagcgg gccgctgaac ccgtccggcc tggaatagcc
      541 ggtcatcagt cgcatctcgg cggaggccac gtcggagttc tgcgtcggct ggtacttgcg
      601 gaggatctgg ccggcctcgt caggatgctc gatggagtac cgcagcccct tgagcaacgc
      661 gccactgaac cgccggacga gttcagggtc ccgatctgcc aggtccttcg tcgtgaccag
      721 catgttgccg tacaggtccg gcaggagatc gccgtagggc aggacgacag ccttgcgtcc
      781 ggccgccgcc gcctcgatca gcggcttgcc gacgacgaac tggccgatcg cgtcgacctg
      841 accggagacc agcaactgcg gcagcgcagg cggcgccgag ggcacgaact cgaccttgcc
      901 ggcgtcgatg cccgcggcct tggcgtacaa cgggaacatc agcttgaccg ttgagccggg
      961 cgggtcggcg accttcttgc cgatgaggtc cgccggcgtc gcgatccggc caccttcgag
     1021 cccgatgatg gccgccacgg tgcgctgctg gaccgcggcg accgcgatca caggcagttt
     1081 ctccttcgcc agcgtgatca tcgtgccggt ggcgtcggcg accccgaagt gcgcccgtcc
     1141 gccggccacc agcttgagca cgtccaccgt gccgctgccg gggttgatcg tcacgtcgag
     1201 accggcctcg gtgaagaaac ccttgtcctg cgcgacatag gcgtacgcgt cgcgcccgaa
     1261 cgtgctgaac gacgtgaggt aggagacctt ggtcgtggtg cccgccgccc ccggctcacc
     1321 cgtgcaggcg actgacgcgg aaagaagaag gatcgcaaga cacgctgaac gaatgggccg
     1381 catcgccggc tcctctccca gagatgtcat ccaaacaact ctggtgagag cgggtcaagg
     1441 cgtgaacacg agcagggatc gcgcgccggt gcctgctctc atccggtcga acgtgccgac
     1501 gccgacgatc gccacccgag gttggcgggg tgggtggcga tccatccggc gacgctggcc
     1561 gacaccggaa tccgtcagtc ggggcgcgag gccacagcag gccgtcgctc actgtccggc
     1621 ctgtgggatg gtggcgacca gtacggcgcc gacgtcgctg ggggcgatct tcagagtgcc
     1681 gccgtgctcc ctggcgatct ccctcgcgat cgccagtccg agtccggacc caccgcgatc
     1741 ccgggtgcgg gcctcatcca accggacgaa gcgatcgaag acccgttccc tgtctggttc
     1801 gggtattccc gcgccgtcat cggttacggt caacacagcc tggcccgtcg agacggcgag
     1861 ggtgacggtt gtccgggagg cggcatggcg ttcggcgttg tcaagcagat tgcgaagcat
     1921 tcgtcgcaga tgagttggat tgccttgcac tgtcacggag cttcgcacgt ctgtgatgac
     1981 cggtcgatcc gctgcctcgt cggccaccaa tgccgacagg tcgacgagtt gtcgcgtgtt
     2041 tgcgtgcttg tcctccagtc tggccaacag catcaggtcg gataccaggc tttgcaagcg
     2101 ttccacatcg gacattgact ttgtgcacac ctcctgccag ttcatccgat ccggataggt
     2161 cagcagcact tccagccgtg tccgcagcgt cgccaagggg ccgcgtaact cgtgcgagga
     2221 gtccgcgacg aactgccgct gccgttgtgt cgagcggtcc aggcgggtga gcatgtcgtt
     2281 catggtttcg gccagcaggg acagttcgtc ccctgttctc ggcaccggaa ctcggcggcg
     2341 cagtccttca ctggtgatgt cggcgacttc aaaccggatc gcgttcacgg gccgcaacgc
     2401 tcgccgtacc gacagccaag cgaccactgc gatgagtacc acgccaatcg gtacagttgt
     2461 ccatgctgtc gcccgcgcgg tggccaccgg ctcatgtgtc cctgcgtcga gcctttcgcc
     2521 agcgtagaca gtgtattcgc tgtcgttgat cgtgacctgg gcgacttgca gatcacggtc
     2581 cagcgggtaa gtgccggcgg tgtaacagtt cgccgcgatg tcgcccggag cggtctgcgg
     2641 aagcgtcact cggtatggcg ggctttcctt tgccagcatt gccaagaacg gtacgtcagg
     2701 atgcgccgtg caggcaggcg ggaaggacgc cacccgccgc ccggtgtcct tgtcgacaac
     2761 ttcccatggc cccagcgaac ccagttcggg cagtctgccg ggaacatcgt tcgcggtctc
     2821 cagcgtcacc gcgaccgcgt gcgctttctg ctgcgcgatc tcgaagacct tggcgtccgc
     2881 ctcgtcctgc agctgtccga tgaaccaggc ggtgcccaca accagcacca cagcggatcc
     2941 cgccgcggcg gtcagggcca cccgcaggcg cgtcgacaga cgccacttcc ggctggtcac
     3001 ctctggcccg tcaactggta tcccgcgcca cggatcgtct tgatcgtgcg ccgcccgaac
     3061 ggggcgtcga tctttccgcg cagcgcgctg atgtgcacct cgaccaggtt gggatcgacc
     3121 tcggccgcga agtcccagag gttcgcgacc aggtcggctt tgctgaccac ttcaccggcg
     3181 cgttcgagca gataggcgag gatcgcggtt tccttggggg tgagcgggat gtccacctcc
     3241 ccgcggcggc atcggcgggt gccgagatcg aggctgaggt cgtccagccg cagcacgctc
     3301 ggggagctcg aaccaccacg gcgcaccaac gcccgcagtc gtgccagcag gacttggtag
     3361 gagaacggct tgaccaggaa gtcgtccgcg ccggtatcca acgcctcgat ctggtcgtac
     3421 tcgccgtcct tcgaggtcag caccaggatc ggagtgtcgt tgtcggttgc gcgtaaccgc
     3481 tggcagacct ggtatccgtt cagtccgggc agcatgatgt ccagtactac ggcagcgtat
     3541 ctgtaccggc tggcaagcca cagaccgtcc gcgccgtcga acgcgagatc gaccgcatag
     3601 ccctcggctg tcaggcccgc cttgagcgtc tcggccaacc ctgtctcgtc ctcgacaacc
     3661 aggaccctca tccggccatc ctggcacagg accacaacct ccaccttgga catccgaagc
     3721 tgaagagacg ttcaggcgcg ttcaggttga gctcaggttc ggatcgcgat cgtgctccgg
     3781 tgccaatccc gcaatggctg acacgtgatc cgcttccccg agcccttgcc gccgcagcct
     3841 ccgcttccta cgcgacccat tcgatccggc tgcaccggtc gttccagagc agtggttacg
     3901 acctgggcat cttcgaacag atcgtcaagt cgtacgccga cggccgttgg cccaccgccg
     3961 acctgctcgg ccccggcgca cccgcgctcg ccgaccactt ccacccgatc ctcgtcgttc
     4021 tcgcgccgtt ctacttgctt ttcccctacc cggaaacctt gctggtggcc cagtcctgcc
     4081 tgttcgcggt ctcggtcgtg cccgtcaccc gactggccct gcgtgttcac ggcaagccgg
     4141 ttgggagcgt gatcggaatc ggctacgcga tgtcgtgggg cttgtggagc gcggtggact
     4201 tcgacttcca cgagatctgc ttcgccgttc ccctggtcgc tctcgcggtg gaacgactcg
     4261 cgacccagca gtggaaagcc gctgccgcgt atgcgcttcc cctgttgctg gtgaaggaag
     4321 agttggcgct caccgtgatg ggtatcggcc tgtatctgat atggcggaaa caacggcctg
     4381 tcggcctggc tttgacgatc ttcagcgtga cgagcttcat cctggtgatc gtcgtgatca
     4441 tgcccgcact cagcacggat gccagctacc accagattcg ttcgctcacc gcacccatcg
     4501 cgacccccat cgtggccggt tgggacacca aactcgtcac ggttcttgcg ttgctcgctc
     4561 ctacggcgtt cgtcgcgctt cggtccccca cggtcgcact cgccattcca accctcgggt
     4621 ggcgtttcgc gtccggaact cctacccatt ggggtatcta cgcgcattac agcgcggttc
     4681 tgatgccgat tgttttcgtg gcgttcgtcg atggacttcg tcgtctacaa gagacgaggc
     4741 ggagcattcc gtgtgcagcg gtcgtgacat gcctggtcgt gacctcgctg accactgtca
     4801 tgctcgcgat ccgcgcaccg gggaaaccca gatggacagc cgatcagcag gccgcggcac
     4861 gacacgcgct gacccttgtt ccggacggtg tgacagtggc cgcttccaac cgactggcac
     4921 cgcagttgac caatcggtgc cgggtcatgt tgtaccggtc cgagcagtcc accaggtcgc
     4981 agtggattgt gctggaccgg caagcggata cgccgccgac aaccggttac gtggtgatcg
     5041 ccgaactgcc acacctggcc atcttcacaa tgtccgcaag cggtcacaca ccaaccgggt
     5101 ccgtctggtg gaccaaacct caagtggcac tgcggaaacc gggtactgct acgacgccgc
     5161 tgaccggatc ctcgccacta ccggggcgaa cgcggtcaca ggcgcgaagt acaacagcca
     5221 cggctcgacg atcgagtaca cctcgggcac cagcgtcacg acattggcct gggacggtgc
     5281 cgaccgcaac acctcagcac gcatcaccgg ccccgacccg ctagcctgac catgcgcacg
     5341 agttttcgag cagtacaggc acgggcacgg tggcgcagct caattggggg agcggctctg
     5401 cgatctcttg cgggcaggag aacttggccg gtgtcggcgc cgcggcgggc tcagtcgtcg
     5461 tggtgatcat ggcggcgaac gcgactcgtc tcctcgtgga aggttcctcc tggactcatt
     5521 tccttgtgta ccaagggtcc tggtagctga ccgatgccgc ggctcgcgta ctggcaaccg
     5581 cggcaatggt tcggtcattc gacttcgaag tggacggttg tcagggtttc tgccacttct
     5641 ggttgggtgt tgtgtcgcag ggcagcactt gcaggccgcc gccgaagcgg tcggccagtc
     5701 atcggctgcc cgatccgggc caacacgaag ttcaacaccg tccgcaactt cacccaccac
     5761 attcggccag gagaccgttt cgtcgcagtc aacgacccgt ccagcgtcgc ggccgtgaag
     5821 aaacacggta tcggagcaac ggtcgtgcac gtcaacaaca cgaccgccgc gcgttcagtg
     5881 accgtggatc tctcacggtt cggcgttgtg acatcacagg cgtccgtgac gcctgtggtg
     5941 accagcgcga gcggcgctct tgtccgtggc gctccagtcg gcgtgaccgg gcgatccgcc
     6001 accctgaccg ttccggcgaa gtcggtgacg acgttccttg tggacggtgt ctctgacgtt
     6061 cgtcaacgtg gccactggcc gactgttgga cgttgccgga cagtccaccg cggatggcgc
     6121 gaaggtttcg acatggactc ccacctcggg gccgaaccaa cggtgggccg tgacctagaa
     6181 gggcggtact agccgccaat cgccgaacag gcaacggaac tgctcacggg cgagagcgtt
     6241 gctgggcaga tcaaggtgcc cgccggtggg gtccgtgtcg tcgtccagcc attgcggtga
     6301 cattcgtgac gccaccagcc gggctagtcc tttgtggaca atgctgcgaa gtcaagtagc
     6361 aggatgcccc cgtgatctcg acagcaggtc ggacgtcagc ggaagtcatc cacgtgatca
     6421 cgcgcccact cagcgtaggt gcggccggtt ttccccgttg ccaggccgaa atcgggcagc
     6481 ggcttcatga ggtccgagta gtcctggtcg gagtagccct ggtcgccgga accctcgccg
     6541 ccgtcgtagt cgacgaaccc gagctgcagg tcggcgctct cggcggcgaa accgcccatc
     6601 gctttgagga tgtcacgggc ctcctcgcgc gtgacctcct cgtagtgcac cgtttcgttg
     6661 agcgcatctg cgatcgcctg cacttggccg cgtacggtga gctgttccgg gccgctgagt
     6721 gtgtacgcct tgccgacgtg cttgtcttcc agcaacgcca cggcgacggt cgcgatgtcc
     6781 gcctcgtgga tcggggcgct gccgaggtcg tcgccgaacg ggtagcgcac tgtccgcgac
     6841 tccttgatca tcgggcccca gatcggcagc atgttcgtca tgaactcccc ggggcgcacg
     6901 tgggtccact cgagcccgga ttcctcgacc gcgcgctcga cgcggacgtg gtagccggtg
     6961 tcgaagccga gggttacggc cgcggcggac agcacgacga tgcgccgcac gcccgcctgc
     7021 ttggcgaggt cgacgacttc ggcggcggtc tccggctgcg ggaacaggaa gagcttctgc
     7081 acaccttcga acgcgggtac gaccgacgcg ggctcgagga ggtcaccttg gaagacctcg
     7141 acgccttcgg gcaacctggc cttcgccggg ttgcgggtca gcgcccgcac cgactctccc
     7201 gcctgcacga gctggccgac gacgtgcctg ccgaccagac ccgtcgcacc ggtcaccaag
     7261 atcgtcatag ctgctactcc tcaccttttg tgctggtcaa tcccaaggta gacgcaactt
     7321 aggccacttc ctgaccgcta ttgacaccga acgggaaggt ctttcagccg cccatgaaga
     7381 aagtcgggtg cggatgaatg tccggcgcga cgggtcaggg ctggggttgt gtggtgagta
     7441 gctgggtggc ggcgagttga cggtagagcg cgtcggtgga gatcaggtgc gtgtgagtgc
     7501 cgttcgcgcg gagcctgccg gcgtcgagga ccaggattcg gtcggcgctg gtgacagtgg
     7561 acaggcggtg cgccgcgacg aggacggtgg tgctgcgggc cagttcggcc accacttgac
     7621 gcagttggtg ttcgttcacg gcgtcgagtt gtgaggtggc ttcgtcgaga agcagcagcc
     7681 gtgggcggcg tagcagcgcg cgggcgatgg cgattcgctg gcgctgcccg ccggacagcg
     7741 tgagcccgcg gtggcccaac atcgtgtcca gcccgtcggg aagacggggc agcaggtcgt
     7801 ccagccgggt gcgaacgatg acgtcgtgga tgtcctcgtc cgaggcatga ggtgcggcga
     7861 ggcggaggtt gtcgcgcaat gtcgcggcca gcacgggagc gtcctgctcg acgtagccga
     7921 tggcggcgcg cagttcggcg aggggccagt cgcgtacgtc gcggccgtcg agcaggatgc
     7981 tgcccgcagc gggttcgtag aaacgttcca gcagagcgaa gatcgtcgac ttgccggcgc
     8041 ctgaaggacc cacgaacgcg gtcatcccac caggtggtgt ctggaagctg atgtcggtga
     8101 ggaccgattc ccggttgccg gggtagccga acgaaacact gtgaaaggcc accgaagcag
     8161 gccccgtcgc cgtcaccgtg gcgggcgcgc cctgggcagc gggttcggtg ggcaggatgt
     8221 gcacctgccg ggtgcggcgt accgccgcga ggccggcctg caggtcgctt gccgcgttca
     8281 ccagggcggc gatgggcgtg atcatgtaga acacgtagag caggaacgcg atcagcgcgg
     8341 acaggggcag tgttccatcg gctactcgtg ccccgccgac gccgagcacc gccagaaacg
     8401 acacgtggac cgacaaccgc gccaggatgc cgaccatcga tgaccagacc gcgacggaca
     8461 ctccctgccg ccaggcccgg tcggcggcct ggtcgaggac cgcgttctcc cgctcttcgg
     8521 cgccactcgc cttcaccgtc cggaaggcgc cgagcgcacg ctccagcacc gctcccatct
     8581 cgccgacagc ctgctgcgcg cgctcggatg cacgcccgat ccgcggcacg accgatccgg
     8641 tcagcacgac ggtcaccagg atgacggcga gcgtgacgcc gagcagtacg ggatccagca
     8701 gtgccatcag cacgatggtg cccaagatca tcagcgttcc gttggcggcc tcgacgatcg
     8761 tgctcgtggc tgcggtacgc agcaaggtcg tatcagaggt cacccgggac agcaggtcgc
     8821 ccggcttgag ccgatcgaat tccgcgacag gcaatcgcag cagccggtgg acaagcccgc
     8881 gcctggccac cagtacgacc ccctcggcgg cacgttccag cagataggtt ccgatcgcgg
     8941 cgatcacggc ggcgccgacg acaagcccgg tcagcaggat gatcggggtg aggacgggct
     9001 cgttcgcgga caacgcgtcg atgactgcct tggcggccag cggctgggcc agcccggcga
     9061 gcccgccgac gcagctgatc acagccgcga cgagcaacgt gcggcggtaa gggcgggcat
     9121 ggccgagcag cagccgccag gcagagccgg gcttcccatc gtccactgtg gacttcatgc
     9181 ggccggggcc agcgcgcggt acatggtcag gtgccggtcg aaggcgatgc cgccgttggc
     9241 gtgcatctgt tcggccccgg tgaggaaccg gcggtggaac tcggcggccc ggtcgggcgg
     9301 cagccactcg accgaaccgg acgacaccgc ggcaggcagg cgcgaggcga acagatccca
     9361 cagcgccgcg ggatcggaga ccggctcagg gtgttcgaaa tccttgcggg tcaagccggt
     9421 gaatccggcc gctgccagca gtccggtcac gtccacatcc gtttgcccgt cccggtcctc
     9481 ggccacggtg gcgggaaaga actcctgagc caggtcgacg agccactgcc agcgaccgcg
     9541 gtgcggaagc ggtcctggca cggacagagc gaacaccccg cctggccgca gcacgcgccg
     9601 cacctcggcc actgccaccg ccggatcgga cagcaggtcg atcacgaagc ccgcggtgac
     9661 catgtcgaag caggcatcag gaaaggccaa gcggtgagcg tccagcatcg acacggcaac
     9721 ggtgggaaag tccgcgcgca ggcgagcgac catgcctggg gcggcgtccc cagcggtgac
     9781 caagcaaccg cgggccaacg cggcccgcac gacagcgcca cggccggcgc ccacgtccag
     9841 cagccgggct cctggcaccg ggtcggcgta gtccagtaac agccggccga actcgagcgt
     9901 ggccggatcc agctcttcgt atatgcctgc gttgtcgtcg taccactgcc aggactgctc
     9961 ggtctgggtc atggggatct cctccacctg ggtctcgtgt tcatggcacg gtgaagaacg
    10021 tccggaagta gccatcgggg tagtcctcgc cgaccatcac gccgtcgacc tcgacccatg
    10081 cgtgggcgta gaacggggcg agccgccgcg cgccgaggca ccaggtcggc cagtggccgt
    10141 acgaacggca cagcaggatt gtggccaagg atcggagcag acatccttcg cgtcccgcgc
    10201 aggccaagct caccgacacc acggcctgtc gggcgtcgca cgtttcctca taggtggccg
    10261 gccgaacgtc ccggtgcaac caggccagca ccttgcggat gcgctgtggc gacctggtgg
    10321 ccagcaagcg ggcggcagcc accatcgccc gcacccggat ccggcgtccg aacgacaccg
    10381 agcggggatc gtacgaaatg gactctgggc tggacatggc ttctccctac tgctcgacca
    10441 gtcgcgcgga acgcagatcg gccaggaggt cccgcacgtc ccgggtcgcg tcgtcgagac
    10501 tgaccccgta ctcctcagtg agcgcctgtg ccgcctgtcc ggctgtgccg ccggccatca
    10561 gggtgcgcag cacgagtgcg ccggttccgt tgaggtcgta gtactcgcca ctgtcgccgt
    10621 cgagcagcac gatcccgtac tcggtctcgg cgtcgaaaac gccgggacgc agcttcagcg
    10681 ccatgagact ctccttatcg gggcaccgtg tggcgttcca gcgcgcgcaa ccagatctcg
    10741 cacgcgaggg tgggatagag cgcactgaac tccacggccg tcggcaatgg gcgtgcgcag
    10801 acctcccgga gcgcgtcctc gtcgatcaag ccgagcttgc caagccggga gttgtcacac
    10861 agggccagca tgtcggcgcg gttctcgcgc agtccgacct cgacctcatg cgctccgatg
    10921 gccttggtct ggcgggtaag ggtttcgtcc gggacgatgc cgcgcatcgc ttcgacagca
    10981 aggggtttga accgccaagg ggtcacccgt tcttgcgggc gcaccgcgag gcccgcctcg
    11041 atcacccggt cgtcgaagta gggcgcggcc agtctgactc cccgctgacg agcgagctcg
    11101 ccgaggttgc gaaccatgcg tgcgacgcct cccaggtccg cgagctcctg atgctggccg
    11161 tggccgtgac ccagcggttc ggcggcgggc gcggcgctgc ggatcaggtc gcggaccgcc
    11221 gccaccgcat ccggtgtcgt ccaagggggc agccgaaccg gcttggccca gtagaagctc
    11281 ggcccgagtg aggacagtgg gcctgcggtc agttcggcgc cgaaccggag cagccatgcc
    11341 tggtaggact cgctgttcag cagttgccgc agcgccatcc ggtaaggcca ccggttgagc
    11401 gccgcgtagc cgcgcaggtt ccgcaatgcg atgcggggct ggcgccgcag catggtgtgc
    11461 agatgagcgg gcgagccgcc cagcacttgg tcaccaccga aaccggtgag gtgcgtcgtt
    11521 gacccgcgcg ccgccgcccg gtcggcgatg accagccacc tgcgatcgag agtgaccgca
    11581 cacggttcgt ccagcgcgac gtcgtcttgc tcgccgatgc cggagaaggc gaacggggcg
    11641 cactcggagg gaacgacgtg atgctcgatg gtgtccagcg cggccaccgt ccgccgcgcc
    11701 cagaacacgt catccgcgag tggatccggc ggcgcccagg tataggcggc cacgtgtgcc
    11761 gggccgcggg cagccaggca gcacaaggaa gtggtgtcga agccgcccag atcggtggag
    11821 atcagatcat ggccccgcgt ccgtacctcg acggcgcccg acaacgccgc gcgcagcgcg
    11881 ggcgcgccct cggccatcgg cacggtaggc tccggcgcgg tccaccaccg cacatgcctg
    11941 tgccgcccag caccgtcgat cgtcaggtag gacccagcgg gcacggccgc caggccacgc
    12001 cacatcggct gtccgccgat cggatgtggg gcgcacggtt cgagcagcgc taccgtcagc
    12061 cgagcctcat ccagtgcggc tccagtgagg cctgccagca catcggcgcg gttggcagcc
    12121 accgtgacgc cgtcgacgct cgcatggagc acccggcgga agccactgat cgggctctgg
    12181 acgcggacct ggcctgccac cgaggcgatc aggtggaagt tgcctgccca cgatgaggat
    12241 ggttcgtcga ggtcggcgag agtaccgaca cggccggcga cccgtgtcag gaatgcggcc
    12301 gagagcaggt gctcgccgat gacggcgatc gcggtgccgc ggctctcggc gacggtgatc
    12361 tcctcctggg cccaccggcc gaccagccag gttcgcccgg aaggatgccg cgtcacgcat
    12421 gtcgcctggc tccgcagcgc cgcggcgacc ggttcggccg cccggcagtc ggggagcacg
    12481 acaaaccatg agggcacgtg atcgaggcgg gcataggtca cggccggact ccttcccggt
    12541 ggtgtacgag cacgccgggt ggtgcggtgc ccacccggac tcgctccccg ggcctgcacg
    12601 gcgactgccg tgcaggcccc aaggagcgag cggtcagccg tcactcacta gttcttgtgg
    12661 gacagaacaa tgaggtcagc cggaccgtga ctgccgacac cggtcttctt ggtgaaggag
    12721 ccagaggccc gcagagtcgg acgctcgtat gtgcgcatcg atttcacctc ctttcgtcat
    12781 atcgctattc gtcgaagcag gcccgtgaca aatttgtgtc acccgccgcg agtaggttac
    12841 gatttcgccg gccggatgaa tcccgcgatg ccgctcttca aacgtcgcaa ggccttgcct
    12901 tcgcatatga gggcaacaag tcttactccg tttcccaggc gcgaatagtg tgcaatgtca
    12961 tttattgagt acgcgcgtgt catcgcggga gtggtgcgat cgtcacggtc gtgacctgct
    13021 gatctccgat gagatccggg cccgtgttca acgattcacg cgaaggaggt aatcgttacg
    13081 ccagagagtt aatcattggt atgagatcaa ttattcggag cacgctccgt aatacgcaag
    13141 acatttttgc gtattcggta ccgaggtgta gttcacaaag ggctgtaaca agcgggacag
    13201 cgaaccctac ggagtgacga gccctgtttg gtaggcgatg acgaccagct gtgcacggtc
    13261 gcgggcaccg agtttcacca tggcatggct gacgtgggta cgggcggtgg ccgggctgag
    13321 gaagagttca gcgccgatct cgtcgttgct catgccctga cccacgagcg ccagaacctc
    13381 acgttcccgt tcggtaagca ctgcgagccg gtgttcggca gccttgttgg ctgttcgctg
    13441 ggcggtgaac tgagcgatga ggcgacgcgt gatgcgcggc gcgagcaggg agtctcctgc
    13501 ggcgaccacc cggatgccat gcagaagctc ggctgggcct gcgtctttga gcatgaaccc
    13561 gcccgcgccg gcttgcaggc cctcgaaaac gtaagcatcg gtgtcgtaag tggtcaggat
    13621 aaggatgcga acctgttgaa ggcctttcgt ggcggcgatc tcccgggtgg cctggatgcc
    13681 gtccatcttc ggcatgcgga tgtccatgag cacgacatcc gggcgcgcgg cgcgggcttg
    13741 ttccacggct tcggcgccgt tggtggcttc cccgaccacc gtgatgtcgt cctcgacgtc
    13801 gagcagaagc ctgaagccgg accgcaccaa ctgctcatcg tcgacgagca ggaccttgat
    13861 cggagcaccg tcgttcgacg cgcctgaggt gttcatacgt tcgccgttcc ggttggggcc
    13921 aagggcagcc gagcggtgac cgcgaatccc ccgcccggga gcgggcccgc gtcaagttct
    13981 ccgcccaaga gctgacaacg ctcgcgcatc ccgaggatcc cgcggcccgg cttgtcccag
    14041 ccgtcatccg ggtgcggggc cgcttcgtcc cttcccgcag gctctcgacg gccctcgtct
    14101 cgcacacgga tctccacggt gtcggcgccg tactccagtc cgaccgtgac ccgagtcggg
    14161 ccgacgtggc gaatcacgtt ggtgatcgac tcctgcagga ttcggtacac ggcactgccc
    14221 accgcactgg gcaccggcga aggcggtgag gacgccacaa ggtcgacgtc gagcccggct
    14281 tcgcgcgcct tggcggtgag atcgtcgatc tggccgagac cggggtgcgg gacgcggccg
    14341 tcgttgtcgt cacggaggac tcccaggatg gaccgcatct cctgcagcgc atgggagctg
    14401 gtcttctcaa tggcctcaag ggtctcgcgt gctcgttccg gccgcttgtc gagcacatgc
    14461 gcggtgacgc cggcttggac gttgatgatg gcgatggcgt gtgcgacggt gtcgtggact
    14521 tcgcgcgcga tcctgagccg ttcctcgtcg acccgggctc gcgcttcttc ctcgcgcgtc
    14581 cgctccgcca gctcggcgcg ttccagcgct tcggccgcga tgaacttcct cgaccggaca
    14641 ctctcgccga gtgcggcact catgaccgaa gcgccgatcc ggaagaacac ccagccgatg
    14701 gcggctggtg gctggatgtc ggcggcagcg agcagccagc acgctgccat ggccgcgatc
    14761 cccacaccgg ccgtcaccag tgagcggcgc ccgtcgccga gagcggtgag cgtgtagatg
    14821 gcaacgaaca atccgagcca tccaggcccg tccgggaagt cgagggcgta gtagaccacg
    14881 ctggccagtg ctgtcgcggc gaacaccgcg acgggccagc ggcggcgcac agccacggcc
    14941 gcgccactga cgaccaacag gatgtatccc agatacccaa ggtcggcaag gggacgcagc
    15001 accagttcgg gctctccgct gttgcggacg atcgtgccct ggacctgcat cacggtgatg
    15061 aacagcgcca gcagcacgtc ctgcgcccag gcaggcaggc gaaacagcat gacgcgaacc
    15121 tgcatgccgc gatcataggg ttcccagccg cgcgggcgcc tacgtcgagg agcgcggttc
    15181 ggggcgagcc gcctacgtcg atcttcgtat ccactgccgc ctgctgaccg aggacacccc
    15241 gatctcacga cgcgacgatt gttcgcgtcc agccattcga tcgaaaggac ctcgatgtcc
    15301 gcccttcact tgcttgcctc ggaagtctca atcaccgccg cgggttacga actcggcgtc
    15361 gggcgaaccg tgcccaccgt ggcagccctg ctggggttga ccagcgtgat cttcggcggg
    15421 ctggcactgg cccgatcccg ccgcaccggg atgatcgtgg ccctggtgct gggaccgatc
    15481 agcatgatcg tcggcggggt ccatggtgcc aacgccgccg gtggtctcgg caccggcaac
    15541 gggctcgccg gcgccatttt cgccgtggtg ctggggctga tcggcgtggt ccttggtgga
    15601 ctgtcgctgg cccgctcccg tcgcaccggc cgatccgttc gctgatgcgc gacaggttac
    15661 ccgcaggcta acggatttcc ggttgtacta acgagtacga caccgcgccg tcacggcaac
    15721 ccgttgaaag gtcaacaagg ctctcgatca cggatcttct gggaagggag ccacgatgag
    15781 ccctgacgtg acgcgtcgcg ctctgctgcg atcaatcggt gtcgcgggtg gtgcgggagt
    15841 gatgttcgaa tccatgcggg cactggggct ggtcgcctcg ccggaggcac tcgcgacgcc
    15901 cgcctaccag ccacccgcca ccggtgatct cacggttgcc aagcgcggca agaaggttgt
    15961 catcctcggg gccgggatag ccggccttgt cactgcctac gagctcggca aggccggtta
    16021 cgactgcacg atcctcgagg cgaatgaccg tgtcggcggc cgcaactgga cggtgcgtgg
    16081 cggcacgacc atgaccgatc tcgacgccaa cacccagacc gcgaagttcg cgcacggcca
    16141 gtacctcaac gctggaccgg cccggctgcc gcagtcgcac atcacactcg actactgccg
    16201 tgaactcggt gttccggtgg aaacgttcat caaccagaac gccaacgcgt tgctctacaa
    16261 cgagcagtcc ggcgtcgctg cacagcagta ccggaccgcg aaggcagact tctacggtta
    16321 catctccgaa ctgctggcga aggccgtcga ccacggttcg ctcgaccaaa gcctgtcagg
    16381 cgaggacaag gaccggctgc tgaccttcct gtccgggttc ggcgcgatcg gtgaccgtgc
    16441 cgacggattc gcctacacag gcaccagtcg gcgcggctac tcggtggagc ccggcgcggc
    16501 ggagcaggct ggtgtggtgc tcggcccacc gccgtcactg tccactgtgc tcgccagcca
    16561 ggtcggccgg tacttctcgt tcgagttcgg ctacgaccag gcgatgacga tgttgcagcc
    16621 ggtcggcggc atggacgcga tccccatggc gttgtaccgc gcgatcggcc gtcacaaggt
    16681 gcgattaggc gcggcggtca ccaaggtcac cgatctcgcc catggcgtcg aggtcgtgta
    16741 caaggacgcc aggggcaaag aggttctcgt gcgtgccgac ttctgcgtgg ccgccctccc
    16801 accgcacgtg atggctcgca ttccgaccaa tttggacgcg ggtgtgacgg ccgcgctgcg
    16861 ctatccgacc gcgacaccaa gtggcaagat cgggcttgaa taccggcgcc ggtggtggga
    16921 acaggacgac cggatctacg gcggtatcac cgaaactgac ctcgacctcg cccacatctg
    16981 gtacccgtct tacggtttcc acggtgaacg aggtgttgtc gtcggctact acaacactgg
    17041 ggcgaacgcc accgcctatg gttccctgtc gcatgtggaa cggaccaagc gcgctgtcgc
    17101 gcagggcgtg aagatccacg gcaagaagta cagcgacgag ctcgtcagtt cgttctccgt
    17161 tgcctggcaa agagtccgtc acatcgaggg agcctgggtc agctggccgt caaggaccag
    17221 cggtgaatac gcattgctga acaagcccgc cgggcgcgtg tacttcgctg gcgactggct
    17281 gagctatttc atcgcatggc aggcaggtgc catcgactcg gcccgttacg tcgtcaccaa
    17341 catccatcag cgcgtcatgg cggaaaggta agcacatgaa ccggttctca cgtcggcgat
    17401 tgggcatcgt cgccggtggc acagccgcgg cactcggcgt cggcaccacg gacgcggcag
    17461 cgtccggtgg gcgaaaagcc ccacgtccca ccgaggttcg cttcaacctg ccgccgggcg
    17521 gcaccaatcc ttcgatcgcc aacggtgtcg cggtcggcag catggtggcc gtgtacacga
    17581 gcagcggact cgggccggcc gcggcgaatc cgtccgcgcc cgccggctcg ccggaacagt
    17641 acgtcgacct ctcactgttc cccggtggga agctaccggc cggcgtgacc gtcaccgagg
    17701 cacaggcctg gaacacactg acccggatcg tggacaacct gacgaccgtg ggactgcgcc
    17761 ctcgtgacgt aatcacgatg aagtgttatc tcaaacgccc cgcgggtgcg tccgatgccg
    17821 attacgccgg ctggaaccgg gcctaccgcc agttcttcgc caacgtcgac ctcggcaccg
    17881 gcgcaccgat cccggtgccg accggaaccg gggcagcggc tccagcgaag atcctcaacc
    17941 cggcccggcc tgctcgtgcg acgcttgagg tggccggtct ggccgtgcct ggctggttga
    18001 tcgaagtcga ggtccaggcc acgtatcact gaccggagcc tggtgcgacc gcggtatccg
    18061 ccgggatgat tctcggatgg acggacgccc ggatgacgcg acccagatcc tcctggccga
    18121 gtacgcggcg cttcgcgccg aggccgaacg ccgagcgact gttcagtggc acgtcgtcgc
    18181 tttgcacccg accaggctcg ccttccaggg agtcgctgtc ctggccctgg tcggtgccct
    18241 gggggctggc atcttcctgt ggatcacccg gtcgccgtcg tggtatgtga tcgccggctt
    18301 cgcggtgggt tggttgatcg acacgctggc aacggttttc ttgcaccgtt cgatcgtgcg
    18361 gctgacgacc gcgttcatcg ccagccgtga gccgacgggc accctgcgag ccgtggccgc
    18421 cagcagcgga cacgaccact gtcgcaaagg tcgccgatga tccgtcagaa gccggggaaa
    18481 acgcgacgca ggtcgtcgag tgtgatgttg ccgtcgatgg tgacgccgtt gtcgtacggg
    18541 gccttgagac ggccgctgat cagccggaca aacgcttccg gcggcccgtt gaacgtcgcg
    18601 gaaggtgact cgacatggtc aaccacggtg accgcgtcat cgatcaccag accggcgcct
    18661 gggaccgcga cggacaccgg ggcggcgagc tcggccggct tcgcgaggaa attcagcatg
    18721 aaggccacgg gcccggtcag gaggtcgacg agtaccgcgg ccgaatcggc gtccacttcg
    18781 gcgtgcgcgt cgaatgccac gcgcacgtcc caggaatggt tggccacctc gttgagccgc
    18841 atgcccaggg cggtcaccag cgggaccggc tccggcagga acccgaggtc gacggtcagc
    18901 gacgagcgct gctcgggggt gagcgcctcg acggtgtcga gccagcggct gtcgtattcc
    18961 agaaagccct cagcctgcgc tcgcggcgcg gacgcgtccc aacgggccca gatcgtctgg
    19021 ttgtcctcgg ccgtcacggt ctctccggcc gcccgcacaa tcggcgcgcg gccgatctcc
    19081 gcaccgctac cgaggtggga aaggacctgg gcgaccgtcc attccgcggc accgctcgtg
    19141 gcggccaact gatcgtcggt aagggtgcgc acgagaccgg caagcgtgtc atgctcggag
    19201 cgaagtgcag tgatcgtgcg gtctacgagt tggctcatgc cacgcccaac cccggaacgg
    19261 acgcatctgt tcccccgatc aatgcctcac cggcccgccc ccggccagtg ctggtgaacg
    19321 tcccgaactg aacttgccga ggatcgcccc agacgatcga acaggcgctc agtaggaagg
    19381 cgggttcaag cagagcggca tcggcaggct caacggccac ggtggactgc aggccttcca
    19441 cctcagggcc ggtgagggtg ggctgtcgcg cggaaaaagc gtgcacaatg gacagtgcac
    19501 ggaagacgct ctgcgtgccg gtcaccgacg gctcgacagt ggcggcgact gcctttccgg
    19561 tgtgactctg aatagcgtcc gcggcaactt gtactcgttc ggcgttccgg tccatgagta
    19621 cgacgtcggc gcccgcggca gcgagctgtt cggcgatgaa gtagccgatt ccggcattgc
    19681 cgccagtcac ggcatacgcc cggccggcga gcgggggtgg tttccaggtc attctgccga
    19741 tgacctgatg aagctgctcg cccagacgcc atcgaaccgg ggtctccgcg ggaatcgacc
    19801 gcgtagcccg aacgccgaaa cggtcggcag ccgcgggtgg accgcgtcag gcgttcttgg
    19861 ggaaggcgtg cttccttccg ccggtgacgg ccgcggtggc ggcgaccagc agcgccagcg
    19921 cagcccacgt gattgacgcg gctcccaggc ccgcgatgag caggccgccg acgaggccgc
    19981 cagccgcgat ggaccccgaa atgacggtaa tgacgatcga ctgggcgacg tcggcggcct
    20041 cacgggaggc gttgatcgcg gcgccgatga acagggaggc ggaactgccg aaggcgaagc
    20101 cccaggcccc gacggcgatg tagaccagcg cgggcgcgtc ggagagcact gccaggacga
    20161 gcacactgat cgcgaacagc acagtgctgg ccaccacgag cttgcgcagg tggcggtcga
    20221 tatgcatgcc gaccacgagg gtgctcagca cggacgtgac gccgaagacg aacagcacca
    20281 accccgtccg gccctccata cccacgtgcc gcaggaagtc gctgacgtag gtgtagagga
    20341 tgttgtgcgc gatcatgtat gcggcgatcg cgaacaggat gacgcgcagc ccggggatca
    20401 ccagggtgtc ggaaaccttg cggcgctggt ccaccggcag gccgggcaga ttcggcaacg
    20461 tcaccagcgc ccacagcatg gtcagcacgg tcaggccggc gcacgagtag aaggcggcct
    20521 gccacccgcc cagggtgctg agccaggttc ccagtggaat gcccagggct agcccgatgg
    20581 gcgttccagc cagggcgacg gtgatggcgc ggccctgctg tcccgcgggg gcgagccgtg
    20641 cggcgtatcc gccgagctgt ggccagatca tggccgtgcc caggccggcg acgaaccgga
    20701 tcaccagggt cagcgtgtag ttgtcggaca gggcggtgag tgcgttggtg acggccacga
    20761 tggccagggc caccagcagc acgttcttgc gcggccactt cgagaacgcg cgcgtgaggg
    20821 ggatcgccgc gatcgaggtg gccgcggcgt acagggtgac ggtctggccg gtgagcgcga
    20881 cgctcgtgtg cagcgaacgg gccatgtccg ggagcaggcc cgctggcagg cactcggtga
    20941 ggatgcccac gaacccggtg aggaagagcc cgaggagcgc cttgcccgga agacggtctc
    21001 ctccgcgcac tacggcgggg gaagttgtgt gaaccgcttc gggcatgtgc tgctccatca
    21061 gtcggacctg ggcctgcggg gacaggctgg tttcacgtgc ggcgttggtt tcccaccgcg
    21121 gcgccatttc cagaacaccg aggcgggata acgggccggg ttcatccggc ctcttcgccg
    21181 agtcagacag tgaagccgcc gtcgacgttc cagttggcgc cggtgatgaa cgctgcttcc
    21241 ggcccggcca ggtagctgac tgcactggcg atttcttggg gctggccgaa gcgcccgagt
    21301 gccatcagtt cgcgcagcgt gcccgcgatc tcgctgtcct cgggggtcat gtcggtcgcg
    21361 gtgggtccta cctgaaggtt gttgaccgtg ataccgcggg gcccgagttc gcgggccagc
    21421 gcgcgcgtca gtccggcgac cgccgccttc gacatcgcat agatcgacat tccggccagg
    21481 ggcacccggt cagcgttgat gctgccgatg ttgatgatgc gaccggtggt gcccagatgc
    21541 ggcagcgccg cttggattgc ggcgaagaca ccccggatgt tgatggcgac caaccggtcg
    21601 aactgatcca tggtcagcga ttcgatggga cccgcgggga ggatgccggc gttgttgacg
    21661 agaatgtcca ggccgcccaa ctgggtcacg gtctcgtcga tcgacctggt cacctgctcg
    21721 ggatcaccgc tgtcggcctg aagcgcgatc gcggtgcccc cggtttcggc gacctcggcc
    21781 accagcttct cagccgcggc ggccgaggcg ctgtacgtga aggcgaccgc agcgccgtcc
    21841 cccgccagcc gtcgcacgac cgcccttccg ataccgcgcg aacccccggt caccagcgct
    21901 cgccggtccg caagtggtac cgccatgtca tcaccctttt cgatctgcgc attactgcgt
    21961 cttactgaaa tcgcgcgata atgtgccccc ggcttgcaat gcatgcgcgg tggagtttca
    22021 tttcgccgat aacgctacag ttcaaccgcc gtaaaagagg ccggtcactg tagtgaatgg
    22081 tggtgaacta tcaggttccg cgttttcgca ttcgacgtcc gttcatcctt ttggatgtcg
    22141 tgtggcggaa aaacccggct agccacgacc ttttgcttgc aatgctacga gttcggccgt
    22201 ccgctagcct gtccctgttg gtagtactca tgctggacgt acgggcgatc tggatgccgc
    22261 gagaggtgaa gaccgcgtcc acggtcgcgt cgggactggc ccgatgcacc aggtggtcta
    22321 ctgagcagcc tgtggggtgc actggctatt caggccgaca acgcggacgg tcaggccgtg
    22381 cgggccgcgg tcgacgtggc ggcagctgag ttcggcggac tggacatcct ggtcaacaac
    22441 gctggcgtgt ttccctcggg gcccttggac gaggtgacgt tggaggacgt ggaccgcacc
    22501 ttggcgatcc atgcccgatc g
//
