LOCUS       NZ_FWXV01000017        22659 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Kibdelosporangium aridum strain DSM 43828, whole genome shotgun
            sequence.
ACCESSION   NZ_FWXV01000017
VERSION     NZ_FWXV01000017.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium aridum
  ORGANISM  Kibdelosporangium aridum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900176515.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:02:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,283
            CDSs (total)                      :: 11,193
            Genes (coding)                    :: 11,032
            CDSs (with protein)               :: 11,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 3, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 38 of 161
            Pseudo Genes (incomplete)         :: 135 of 161
            Pseudo Genes (internal stop)      :: 6 of 161
            Pseudo Genes (multiple problems)  :: 17 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:58:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 58601
            Orig. end                         :: 81260
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FWXV01000017.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22659
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..22659
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22659
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12659](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12659
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    139..157
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.37"
                     /tool="antismash"
     misc_feature    140..156
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: strong, score: 28.92"
                     /tool="antismash"
     misc_feature    complement(141..155)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 20.78"
                     /tool="antismash"
     misc_feature    complement(142..157)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.57"
                     /tool="antismash"
     gene            complement(181..1143)
                     /locus_tag="B9C43_RS51045"
                     /old_locus_tag="SAMN05661093_10410"
     CDS             complement(181..1143)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019814588.1"
                     /locus_tag="B9C43_RS51045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10410"
                     /product="R2-like ligand-binding oxidase"
                     /protein_id="WP_033390352.1"
                     /transl_table=11
                     /translation="MTDTTAELRTGFASLRKGGLNWDSFPLRLFVKGNAKFWNPADIDF
                     SADRADWESLNDEERRSATYLCAQFIAGEEAVTEDIQPFMKAMAAEGRISDEMYLTQFC
                     FEEAKHTEVFRRWMDAVGLTDDLHPFVAENPYYRKLFYEELPGSLAVLETDPSPLNQIR
                     ASVTYNHVIEGTLALTGYYAWQKICKGRGILPGMQELVRRIGDDERRHMAWGTFTCRRH
                     VAADDSLFDAVIQRMGELLPIALNMIEWVGNQFEEPRPFESDPKEYVEYAGDRAQRRLG
                     AISSARGTPVAQIDLDYSPEVLEDQFGEEDAKVFARIGG"
     gene            complement(1172..1762)
                     /locus_tag="B9C43_RS51050"
                     /old_locus_tag="SAMN05661093_10411"
     CDS             complement(1172..1762)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017985247.1"
                     /locus_tag="B9C43_RS51050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10411"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_143447192.1"
                     /transl_table=11
                     /translation="MTDITPFSERVRMSLRETLLDAAADLLAEHGFAGLRMVDVATSAG
                     VSRQTVYNEFGSKAALVNAVALRTVSEFLDGGEERWRATSDLATGLHAVVEYTVRHGRE
                     NRLVASVLGGAQSEDLLPLLTTRAEPVFRPAIEQTVGNLTERVPALPPEAAAVIAETIV
                     RLSVSHMMLPGGTPCEAADAVCAVILPAIEAHS"
     misc_feature    complement(1562..1564)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1846..2457
                     /locus_tag="B9C43_RS51055"
                     /old_locus_tag="SAMN05661093_10412"
     CDS             1846..2457
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015097967.1"
                     /locus_tag="B9C43_RS51055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10412"
                     /product="HAD family hydrolase"
                     /protein_id="WP_235039322.1"
                     /sec_met_domain="HAD_2 (E-value: 7.2e-16, bitscore: 51.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTVGFDLDMTLIDPRQGIVKAIAALAEETGLSLDGEYIAANMG
                     PPLRDMFLSIGIPEDRIDTSVARFRATYPEIVIPTTVPMPGAAAALKAVRAAGGQTLIV
                     TAKYQRNAELHVEALGWEVDHLIGDLWSAGKADALKLHGAGVYVGDHIGDMKGAAAAGA
                     VAVGVTTGPCDAAMLTEAGADVVLSSLVEFPAWFNDAAPR"
     gene            complement(2435..2620)
                     /locus_tag="B9C43_RS51060"
                     /old_locus_tag="SAMN05661093_10413"
     CDS             complement(2435..2620)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005466421.1"
                     /locus_tag="B9C43_RS51060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10413"
                     /product="hypothetical protein"
                     /protein_id="WP_033390350.1"
                     /transl_table=11
                     /translation="MPRFKLLPAAVAMFAVGLLAIIAVFVLYATGQTNLSVWLYVAAML
                     LPIGLGLGILSVVRRR"
     gene            2766..3152
                     /locus_tag="B9C43_RS51065"
                     /old_locus_tag="SAMN05661093_10414"
     CDS             2766..3152
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019815767.1"
                     /locus_tag="B9C43_RS51065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10414"
                     /product="cold-shock protein"
                     /protein_id="WP_033390349.1"
                     /transl_table=11
                     /translation="MPTGRVKWYDSEKGFGFVTQEGGEDVYVRASALPPGVTGLKAGQR
                     IEFGVADGRRGPQALSVRLIDPMPSVAEARRRPAEELHGLVEDMIKLLEAKVQPDLRRG
                     RYPDRKATKRIAEVVRAVARELDP"
     gene            complement(3201..3656)
                     /locus_tag="B9C43_RS51070"
                     /old_locus_tag="SAMN05661093_10415"
     CDS             complement(3201..3656)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022422.5"
                     /locus_tag="B9C43_RS51070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10415"
                     /product="DUF2771 family protein"
                     /protein_id="WP_084434490.1"
                     /transl_table=11
                     /translation="MRRFGIASLVAGGLLLAGCAAPHDPEVTFFADGETVNIGPSPACD
                     ATLEECRPTGALAVPGGQPLSISVPKQIADAPWLVVFRYRAADGSVQKARSSLFRAGET
                     YAYTLRTPTAGDQLMHVEVQRIGEMGSDENRQLYFGIDASWALTVSS"
     gene            complement(3666..5411)
                     /locus_tag="B9C43_RS51075"
                     /old_locus_tag="SAMN05661093_10416"
     CDS             complement(3666..5411)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337549.1"
                     /locus_tag="B9C43_RS51075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10416"
                     /product="MFS transporter"
                     /protein_id="WP_200826083.1"
                     /transl_table=11
                     /translation="MLRSGSDDQGGDRPAKGRSKGRKWTARQPKQFGSQPQPQPPPPAR
                     RQPPPPPPPPLPEEHRQTTPIRREQPLPPPSGRYGPDGYPAPRTGHTGPYDYYDEGPPQ
                     PPRQQQPPPQPEAQHGSEAATLPRGGLPQAPKKLTVTRVAALRSKQLTQQAVGAFKRAA
                     NADGADKSGLTSLTYATMLNYASDAAMAVALANTLFFAAASADSSKGKIALYLLITVAP
                     FALVAPVIGPALDKIQRGRRLAMCVASAGQALMCIVMATNFDSWLLYPAALGKMVLSKS
                     FTVLKAAVTPRVLPPEITLSKTNARLTVFGLAAGMVFGGIAAGLTQMFDSEGALWFTAL
                     ICVVGAVQGMRIPAWVEVTEGEVPATLSATPTRPKRQPMGQHVVISLWANGTVKVLTGF
                     LMMFSAFAIRAETEGQAFQQLLLLGIIAAAAGIGSFGGNAIGSRLLVTRPDQMVLGCVI
                     ACVTATVVATILPGIGTMAIVSLIAATAAALAKNSLDAVIQHDLPEESRASAFGRSETV
                     LQLGWVFGGALGVLLPTTFWVGFLVISLILGLGMVQTILATKGNSLLNVVRRATPARRA
                     GTEPT"
     gene            complement(5457..6239)
                     /locus_tag="B9C43_RS51080"
                     /old_locus_tag="SAMN05661093_10417"
     CDS             complement(5457..6239)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015787675.1"
                     /locus_tag="B9C43_RS51080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10417"
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="WP_143447199.1"
                     /transl_table=11
                     /translation="MLLVVAACVLAASCGTESGTGTAPAGQAQPARMRAEVLAVLPHDP
                     KAFTQGLELDGDRLYEGTGLEGESSVREVDPQTARVEKKVDLPSPMFGEGVTVSGSTIW
                     QLTWKDGVAIQRDKETLAEVKRVPYTGEGWGLCRDGQRLVMSDGTDKLTFRDPDTFDPI
                     GEVRVRSGNDPVTQLNELECTANGVYANVWQTDTVVRIDPASGAVTASIDLAGLLSPAE
                     RAGADVLNGIAAVPGTDEFLVTGKLWPKMFRVKFVTAS"
     misc_feature    complement(6210..6212)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6283..7032
                     /locus_tag="B9C43_RS51085"
                     /old_locus_tag="SAMN05661093_10418"
     CDS             6283..7032
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012783115.1"
                     /locus_tag="B9C43_RS51085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10418"
                     /product="DUF3027 domain-containing protein"
                     /protein_id="WP_033390348.1"
                     /transl_table=11
                     /translation="MSTTPVPELALAGVVEQARAAAREEAGDEVGAHVGVQPEDEAAVT
                     HLFEADKAGYRGWHWAVTVANSGPGTKVTVSEVVLVPGPDALVAPAWVPWQQRVQAGDL
                     GVGDLLPTSPDDPRLVPAYVQSDDEAVEEVAREIGLGRVRVMSRPARLDAASRWQDSEF
                     GPRSDMARSAPEHCGTCGFYLQVAGSLRAAFGVCGNEISPADGHVVHVQYGCGAHSELR
                     IDQGSPVLVADLIYDDSLLDVERAPAE"
     gene            7059..9908
                     /locus_tag="B9C43_RS51090"
                     /old_locus_tag="SAMN05661093_10419"
     CDS             7059..9908
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156113.1"
                     /locus_tag="B9C43_RS51090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10419"
                     /product="sacsin N-terminal ATP-binding-like
                     domain-containing protein"
                     /protein_id="WP_084434533.1"
                     /transl_table=11
                     /translation="MNTDPFGTQRLREAVLAAWSASPTRFREDANAEEDLRLGAYRDRL
                     LVELAQNAADAAGFGGRLRLSIVDNELRAANTGAPLDAEGVAALASLRASAKRDILGTV
                     GQFGVGFSAVLSVTDEPEVVSTTGAVRFSARRTREIPEIQDHVAARSGQVPVLRMVWPT
                     DSVVPEGFDTEVRLPLRPDVDHAALLENFREQAPDLLLALPGLASIEVGGSVWTSTDSG
                     DTVVLTGPEGTTRWMLRRATGKLSDTAGLGMETSTEWMVCWAVPVTESGVPQPLTEDVL
                     HAPTPTDERLSLPARLLASLPIEASRRHVMSSPAVQEVLAEAAKLYPSLVFGVPAMHRT
                     ALVPVPGFPRSDVDAQLRDLLIAELRTQAWLPGVTESLKPASARVLEIPSDALADLLSD
                     VVPNLAAAQLAAPEHAHALAALEISRLRIPEIVAALTGIDQEPSWWRQVYAAIAPFAEN
                     DSAIRDNLSGLPVPLVDGRTLPGPRGTLLADEPEFLSDLDVPGLRLVHPAAAHPLLERL
                     GARHAGAAELLDALQEAVERSVADASAGLIVSGLAHAVLGLVGQAGGRPWLKSLALPDS
                     DGDWRAADELALPGSRFLEVLDPDSPLGLLDPEFAERWSADVLSAVGVLTGFAVIVDEE
                     PIGPEHDLADEDEWWSFGTEEPKRVVAVRDLDLVADDKWPDALRLLALEPATWQALREP
                     GGYTAWWISRYALLDGRAPRFWRTASAHDLVGLYDPLPIELGDELAAAAGVRTHLEIKD
                     ASDAEDLLERLGDPARSVSHGVSLRAHAALAGSVDVSLLDAPERVRVLSGEAVDAEDCV
                     VLDAPWLLAVLPPNRVVAALDDDAAEPLAELLDLPLASESAGDVTGGELVPWAELGAVV
                     VAAELLGFELPLEGVIVHDQLTANGQRVHWWVDRQNRVHCEDTPDGLARALAWASDHWI
                     DRHVIHAILEDPDPRTVLA"
     misc_feature    7089..7091
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7170..7172
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7665..7667
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..10426
                     /locus_tag="B9C43_RS51095"
                     /old_locus_tag="SAMN05661093_10420"
     CDS             10001..10426
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS51095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_10420"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_084434493.1"
                     /sec_met_domain="LANC_like (E-value: 7.3e-07, bitscore:
                     21.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSDPLSVAVEVATRLRDAADDVDANCGIAMLFDELDRIQPGRGW
                     ALAAKDKLASAVRVIEQTGNRSPRLYNGIGTLGLAAWRLSRDGKRYQQVLAEVDRWVVD
                     RASADGRALAERPCSGGRPRNGTSTTRRACATESPGC"
     gene            10504..10671
                     /locus_tag="B9C43_RS57235"
                     /old_locus_tag="SAMN05661093_10421"
     CDS             10504..10671
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS57235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_10421"
                     /product="hypothetical protein"
                     /protein_id="WP_160097327.1"
                     /transl_table=11
                     /translation="MYDPARRYGYEFLGDDGTCIEDRPEFLDGAAGVALALLAATTEQD
                     PAWDRMLLLS"
     misc_feature    10532..10547
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.07"
                     /tool="antismash"
     gene            10683..10841
                     /locus_tag="B9C43_RS57240"
                     /old_locus_tag="SAMN05661093_10422"
     CDS             10683..10841
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS57240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_10422"
                     /product="hypothetical protein"
                     /protein_id="WP_160097329.1"
                     /transl_table=11
                     /translation="MPIRDEFDLDVRLGEPIELGIMRGTPPTTEQCPDSHAVTCGGPCC
                     DRSFSCL"
     CDS_motif       10683..10748
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPIRDEFDLDVRLGEPIELGIM"
                     /locus_tag="B9C43_RS57240_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       10749..10841
                     /prepeptide="core"
                     /locus_tag="B9C43_RS57240_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-8.90"
                     /molecular_weight="3000.3"
                     /monoisotopic_mass="2998.3"
                     /core_sequence="RGTPPTTEQCPDSHAVTCGGPCCDRSFSCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPIRDEFDLDVRLGEPIELGIM"
                     /leader_location="[10682:10748](+)"
                     /alternative_weights="3018.3"
                     /alternative_weights="3036.4"
     gene            10892..11065
                     /locus_tag="B9C43_RS57245"
                     /old_locus_tag="SAMN05661093_10423"
     CDS             10892..11065
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS57245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_10423"
                     /product="hypothetical protein"
                     /protein_id="WP_160097331.1"
                     /transl_table=11
                     /translation="MTASVIDDFDLDIRFGEPIVPQTSPMAGKTSDFESCETESHCGTC
                     GSTCTTTTSRNC"
     CDS_motif       10892..10963
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTASVIDDFDLDIRFGEPIVPQTS"
                     /locus_tag="B9C43_RS57245_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       10964..11065
                     /prepeptide="core"
                     /locus_tag="B9C43_RS57245_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-2.60"
                     /molecular_weight="3199.4"
                     /monoisotopic_mass="3197.3"
                     /core_sequence="PMAGKTSDFESCETESHCGTCGSTCTTTTSRNC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTASVIDDFDLDIRFGEPIVPQTS"
                     /leader_location="[10891:10963](+)"
                     /alternative_weights="3217.5"
                     /alternative_weights="3235.5"
                     /alternative_weights="3253.5"
                     /alternative_weights="3271.5"
                     /alternative_weights="3289.5"
                     /alternative_weights="3307.6"
                     /alternative_weights="3325.6"
                     /alternative_weights="3343.6"
     gene            11157..12659
                     /locus_tag="B9C43_RS51100"
                     /old_locus_tag="SAMN05661093_10424"
     CDS             11157..12659
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="B9C43_RS51100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10424"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_143447193.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.5e-70, bitscore:
                     231.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.5e-25, bitscore:
                     83.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRALAVGAGDLWRAVERQQPSDRALPSLDLSVFVLALSPEAVDA
                     GDFQMMVGPNFGASAAGRVLGRFGDLLGEQARTALRSVADAEAVVRPGRVWAEVNYLPR
                     KGRLGNVATRALVRDHELVLNTTPGGERIIRAADLLVGVRDNRFVLRWSVTGHEVVPCS
                     GHMLNPRSGSPVIQFLDDVSRDGYAMPSSFDWGPAANFPFLPRVQAGRIILTPARWLLR
                     AEEFTQQWRERWQVPRHVYLSTADNRLLLDLADPDQLKQLPDKGLMVLQEALPAPDQAW
                     LPGSEGRYVSEFVVPLIREEIGPEPEPARQIPSGRRMRPPGSDWLFAKLYHLPTFENDL
                     LTGPVKDFCDGNWFFMRYVDPGPHLRIRWTGDPRWLTGELAPRVLRWSAELVERGYCTR
                     VALDTYDRELERYGGPTALEAAESLFAADSSAVLDLLRLNDIDRTLLGMYTVDDLLVGL
                     GLTEDERLGNYRLAVADRRATADEFRSRQVELRRAPLRRGTA"
     gene            12656..14530
                     /locus_tag="B9C43_RS51105"
                     /old_locus_tag="SAMN05661093_10425"
     CDS             12656..14530
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098265.1"
                     /locus_tag="B9C43_RS51105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10425"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_084434495.1"
                     /transl_table=11
                     /translation="MSAPLVGVDEVELPKWTEIDQQVANAGLWHTLRALPSGVSIVLRL
                     AWQASKRLTLLSAILSVAAGCATAFGLIATADVLTTLLAQGPTPTQVVASLPSVALVVA
                     SFSLRALLDSASTAALALLRPHVEQTAQETVHAAVSQVELIAFEDSDYADLLRQCMTAG
                     VRSIESSIKAISGIGGSLVYLIASVVSAGVLHPLLAPVVLIAVIPNMWAYARAAKLAYV
                     SYLAMLSRSRRLSIASELLTARETAAEMRAATARLALLEEYRRISTMLTDEAVRVELKQ
                     TRVRLIGRIIAGVGTGAGYAVLGVLLHAGWLALPLAGAAVVAMRVATSALMTTMMGVKT
                     LYEDTLYVKLYTRLLEISRARTRSPVAAQAPAPAVITLEEASFSYPGQDAPALRDVSLT
                     ITKGQVVALVGENGSGKSTLAKLITGLYQPTGGRVCWDGVDLAEFDEESVYQQIALVLQ
                     DPARWPMTAHDNIRMGRIDRRDGMSVAEAARESGAEDVIAELPNGYQTLLSRLFSSGRD
                     LSGGQWQRISVARGIYRDAPILVVDEPTAAMDAKAEHAVFESLRRLGGGRTTILITHRL
                     ANVQHADQIVVLDQGKLVEQGTHHELMALGGTYAGLFTLQASAYTPRT"
     gene            complement(14696..14974)
                     /locus_tag="B9C43_RS51110"
                     /old_locus_tag="SAMN05661093_10426"
     CDS             complement(14696..14974)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012783117.1"
                     /locus_tag="B9C43_RS51110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10426"
                     /product="DUF2530 domain-containing protein"
                     /protein_id="WP_084434496.1"
                     /transl_table=11
                     /translation="MASTEEPESPGETGKSLPPPPPPPARLVDLFRIVVVGEIVWFGVL
                     VVALFTGPSILAWTAFTGVVLGGIGMAIMTWQRSAARKGSKTAQQGI"
     gene            14993..16453
                     /locus_tag="B9C43_RS51115"
                     /old_locus_tag="SAMN05661093_10427"
     CDS             14993..16453
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020664474.1"
                     /locus_tag="B9C43_RS51115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10427"
                     /product="NCS2 family permease"
                     /protein_id="WP_084434534.1"
                     /transl_table=11
                     /translation="MADTTSRRGALDRFFKISERGSTTGREIRGGLVTFVTMAYIVVLN
                     PLIIGSFAAEGPSAHRDVLGDILPVSQVAAVTALVAGVMTILFGLIANYPFALATGLGI
                     NSFVAVTLAPQMTWAEAMGLVVLNGIVVMVLVLTGVRTAVFNAVPQPLKAAIAVGIGLF
                     ITLIGLVDAGFVRRIPDAANTTVPVGLGISGSIASWPTFVFVVGLLVTGILVAKRVKGA
                     ILIGVLFSTVLAIVLEAIVKAGPSQGVNPKGWNLGYPAMPEQAVGLPDLSLLGEFSFGA
                     WSRVPALTVVLLLFTLILTDFFDSVGTMTGLGKEAGVIGKDGQLPGVGKALFVDSLGAV
                     AGGAASSSSNTVYIESASGIAEGARTGLANVVTGLLFIAAMFLTPLYQVVPVEAAAPAL
                     VIVGVLMMAQIKEIDFTDFSIALPAFLTIVVMPFTYSIANGIGAGFISYVVLKVISGRA
                     KSVHPLLWVVAVAFVAYFAVGPIQGAIG"
     gene            16504..16935
                     /locus_tag="B9C43_RS51120"
                     /old_locus_tag="SAMN05661093_10428"
     CDS             16504..16935
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012783119.1"
                     /locus_tag="B9C43_RS51120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10428"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_033390339.1"
                     /transl_table=11
                     /translation="MSGSADEHSLTSRLRLSVMRLNRRLRAQRTNASVTLSQISALSSL
                     HKCGPMTPGELAAREGVQPPSMTRVIAALEDLGYISKRAHPNDGRQVIVELTERGLGYI
                     EADVAAREAWLDARLSELDESERELLSRAAEIIDRMAGQ"
     gene            16943..18307
                     /locus_tag="B9C43_RS51125"
                     /old_locus_tag="SAMN05661093_10429"
     CDS             16943..18307
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010308734.1"
                     /locus_tag="B9C43_RS51125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10429"
                     /product="MFS transporter"
                     /protein_id="WP_084434535.1"
                     /transl_table=11
                     /translation="MTGAGGTREKKPSNFDSDLPPPPEQPKQGTFSSLRIRNYRLFFSG
                     QVVNNVGTWMNRIAQDWLVFTLTGNNPVALGIAAALQFAPTLFLSLYGGVLADRLDKRK
                     LLIGLQAAMAGCAVILGVLDVSGWVQLWQVYVICFVFGCFTAVETPVRQSFTSEMVGIG
                     LVTNALALNSSSFNLARVVGPAVAGLLIIWVGTGMVFLINAVTTIAVITGLLLMRPSEL
                     HRGPAVARAKGQLREALRYVRGRADLVAVLSLVFCVSTFGITFFTTLAIMAANVFHKEA
                     DGYGLLSTMLAVGTLSGALLAARRSVRGKPKLRMVFGSALVFGVLEIGAGLMPTYLAFA
                     IALVPVGVVVMTFMNTAITTVQLSVEQEMRGRVMGLYMLLFLGGNPIAGLLTGWLADQF
                     GGRSTFYVGGAVSIIAAVVLGLILRWRASLPERRSAAQGEVRGTVRQEEGTTAQT"
     misc_feature    17042..17044
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18264..19274
                     /locus_tag="B9C43_RS51130"
                     /old_locus_tag="SAMN05661093_10430"
     CDS             18264..19274
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS51130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_10430"
                     /product="hypothetical protein"
                     /protein_id="WP_084434497.1"
                     /transl_table=11
                     /translation="MGLFGKKKAQLPRREVIWGHCYDDDLLDAAEAELLEGKLNAAVTV
                     LVDSRENAEARSLRLGRLGHRLVGSADEIAELAAQHRDPELMLLAGDAYIGEAWAIRGS
                     GWASSVGEDRAKMFLTTLEKARGPLEAAAEMLPADATPWAQMVTMGMGLGLDRSEQDAF
                     WAETVKRAPTLYPAHWTRLQVLAEKWYGSHEEMSQFAITTVNNAPHGDPVTAMIVVAYF
                     EVFIQAKARAEREVRKPNLRAMAEGVFKKSYQNIQAASNRWMQAEKPHPRAFEAHNYFA
                     AACGLAGDGDRAFMHLFGMRDRLMSRPWNLFADEPEEEYQSMVQKYWRADLTQGL"
     gene            complement(19529..20158)
                     /locus_tag="B9C43_RS51135"
                     /old_locus_tag="SAMN05661093_10431"
     CDS             complement(19529..20158)
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010308738.1"
                     /locus_tag="B9C43_RS51135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10431"
                     /product="superoxide dismutase"
                     /protein_id="WP_033390337.1"
                     /transl_table=11
                     /translation="MAPYVLPDLDYDYGDLEPAIIGEINELHHGKHHAAYVKGANDTLE
                     KIDEARDKGEFGSIVGLETTLAFNLAGHSLHQVWWKNLSPNGGDKPTGELAAAIDEFFG
                     SFDKLRAQLNAAATTIQGSGWGILSWDPIGQRLLTQQLKDHHANLSIATTPLLAFDVWE
                     HAYYLQYRNVKADYINALWNVVNWEDVNQRFVDARNGLNGLRVPQA"
     misc_feature    20197..20215
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.84"
                     /tool="antismash"
     misc_feature    20198..20214
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 24.93"
                     /tool="antismash"
     gene            complement(20248..20892)
                     /locus_tag="B9C43_RS51140"
                     /old_locus_tag="SAMN05661093_10432"
     CDS             complement(20248..20892)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156094.1"
                     /locus_tag="B9C43_RS51140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10432"
                     /product="heme oxygenase (biliverdin-producing)"
                     /protein_id="WP_084434498.1"
                     /transl_table=11
                     /translation="MSPTFSETLRAATMPAHEQANHSPYISALLGGELSVDAFGQLASQ
                     LYFVYSALEDTAEAMRDDPIAGKFVFSELNRRDALREDMAYYFGPAWESVVEPLPATTE
                     YCARIRSVSWSGEFVAHHYTRYLGDIAGGQVIRHRLRKLHGVEGPGSMFYVFDQIPSAP
                     KFRDNYRALLNSAPWDAEERKRVIVESLRAYELNVAVFAALAEDMPRYSMS"
     gene            complement(20950..21546)
                     /locus_tag="B9C43_RS51145"
                     /old_locus_tag="SAMN05661093_10433"
     CDS             complement(20950..21546)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020641655.1"
                     /locus_tag="B9C43_RS51145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_10433"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_084434499.1"
                     /transl_table=11
                     /translation="MPKILGESLAEHRSQVRAKVFDAMRTLLYTRGFDAITLSGVASAA
                     GVGRTAIYNHFPDRESLLVAFVEHETSQYVIRLREALAAVSDPVEALAVFVRMQLRVLA
                     GRHTPPGAKLNALLSPEAYERMAEHVDPITAELRSILESGIASGQMVDEDVDVLITMIT
                     ASLASREVVDAGAELDNTIETAVRFILRAVGVRVA"
     misc_feature    21775..21788
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.87"
                     /tool="antismash"
ORIGIN
        1 tgccggggtc cacataggcg atggcggcga cgaaggcggg gccgagtaac gcggcaccgg
       61 atctgaatcg gacgatccgg ggtttgatgg cactggctag cgacaacgga cctcccacga
      121 cgaaccgggt gcaaggctac tgcaaatgac ttgcaatagg aggccgcggc gatcgacgtc
      181 tcagccacct attcgcgcga agaccttcgc gtcctcctcg ccgaactggt cctccagcac
      241 ctcgggtgag tagtccaggt cgatctgcgc gaccggcgtg ccacgggccg acgagatggc
      301 accgaggcgg cgctgggcgc ggtcaccagc gtattcgaca tattcttttg gatccgattc
      361 aaaaggccgg ggttcttcga actggttgcc gacccactcg atcatgttca gcgcgatcgg
      421 cagcagctcg cccatccgct ggatgacggc gtcgaacagc gagtcgtccg cggcgacgtg
      481 cctgcggcag gtgaacgtgc cccacgccat gtgcctgcgc tcgtcgtcac cgatccgccg
      541 gaccagctcc tgcatgcccg gcaggatgcc gcggcccttg cagatcttct gccacgcgta
      601 gtagccggtg agggcgagcg tgccctcgat cacgtggttg tacgtcaccg aggcgcggat
      661 ctggttgagc ggactgggat cggtctcgag cacggcgagc gagccgggca gctcctcgta
      721 gaaaagcttg cggtagtaag ggttttccgc gacgaacggg tgcaggtcat cggtcagccc
      781 gaccgcgtcc atccaccgcc ggaacacctc ggtgtgtttg gcttcctcga agcagaactg
      841 ggtgaggtac atctcgtcgg agatccggcc ctccgcggcc atcgccttca tgaacggctg
      901 gatgtcctcg gtcaccgcct cttcgcccgc gatgaactgc gcgcacaggt acgtcgccga
      961 ccgccgttcc tcgtcgttga gcgactccca gtcggcccgg tcggcgctga agtcgatgtc
     1021 ggcggggttc cagaacttcg cgttgccctt gacgaaaagc ctgagcggga acgagtccca
     1081 gttgagcccg cccttgcgca aggacgcgaa cccggtgcga agctcggctg tcgtatcggt
     1141 catgactggc tcctttgcca actgactctg ctcaagaatg ggcttcgatc gcgggcagga
     1201 tcaccgcgca caccgcgtcg gcggcctcgc aaggcgtgcc gccgggcaac atcatgtggc
     1261 tgaccgaaag ccgcacgatg gtctcggcga tcaccgcggc ggcttccggt ggcagcgccg
     1321 ggacccgctc ggtcagattg ccgacggtct gttcgatggc tggccggaaa accggctcgg
     1381 cccgggtggt caacaacggc aacagatcct ccgactgcgc gccaccgaga acggaggcga
     1441 caagccggtt ttccctgccg tgccggacgg tgtactcgac cacggcgtgc aagcccgtgg
     1501 ccagatcgct ggtcgctcgc cagcgttcct caccgccgtc gaggaattcc gagactgtcc
     1561 gtaacgcgac cgcgttcacc aatgcggcct tgctgccgaa ctcgttgtag acggtctgcc
     1621 tgctgacccc ggcgctcgtg gccacgtcga ccatccgcag acccgcgaaa ccgtgctcgg
     1681 ccagcaggtc agccgccgcg tccagcagcg tttcgcgcaa cgacatccgc acgcgttcgg
     1741 agaacggtgt gatatcggtc atcgcccgag tgttgacacg acatccgatt gtgtcaacca
     1801 cttgtactcg attgagggat tcgtaaagtc acctagggtg atggggtgac cgtgaccgtc
     1861 ggcttcgacc tggacatgac cctgatcgac ccgcgccaag gcatcgtcaa agcgatcgcc
     1921 gcgttggccg aggagaccgg gctctcgctg gacggcgagt acatcgccgc caacatgggc
     1981 ccgccgctgc gcgacatgtt cctgtccatc ggcatccccg aggaccggat cgacacctcg
     2041 gtcgcccggt tccgggcgac ctacccggag atcgtcatcc cgacgacggt gccgatgccg
     2101 ggtgccgcgg ccgcgctcaa ggcggtcagg gcagcgggcg ggcagacgct gatcgtcacc
     2161 gcgaagtacc aacgcaacgc cgaactgcac gtcgaggccc tcggctggga ggttgatcac
     2221 ctgatcggcg acctgtggtc ggcgggcaag gccgacgcgc tgaaactgca cggcgcaggc
     2281 gtgtacgtgg gagatcacat cggtgacatg aaaggcgcgg ccgcggcggg cgcagtcgcc
     2341 gtcggcgtca ccacgggacc gtgcgacgcg gccatgctca ccgaggccgg agccgatgtc
     2401 gtgctgtcca gcctcgtcga gttcccagcc tggttcaacg acgccgcacc acgctgagaa
     2461 ttcccagccc cagaccgatc ggcaggagca tcgccgcgac gtacagccac accgagaggt
     2521 tggtctgccc ggtggcgtac agcacgaaaa ccgcgatgat cgcgagcagc ccgacggcga
     2581 acatcgccac cgcggctggc agaagcttga atctgggcac ggctgcagac tatgcgctac
     2641 gccagaaccc gggtttggca taggctagaa cgacgcgtcc tgggcgtgcc tggggcgcgt
     2701 tagtcgtgcg gcgtggaggg tggaaccgtg cggcatgtgg agtcgacgag ggaacggtga
     2761 gagctgtgcc gaccggacgg gtcaaatggt acgactcgga gaagggcttc gggttcgtca
     2821 cgcaggaggg cggggaggac gtgtacgtcc gtgcatccgc gctgccgcct ggcgtgacgg
     2881 gactcaaggc gggacaacgc attgagttcg gggtggcgga cggccgccgt ggcccgcagg
     2941 cgctttcggt gcggctgatc gatccgatgc cctcggtcgc cgaggcgcgc cgccgcccgg
     3001 ccgaggagtt gcacggcctc gtcgaggaca tgatcaagct gctggaagcc aaggtgcagc
     3061 cggacctgcg gcgtggtcgc tacccggatc gcaaggccac caagcgaatc gccgaagtcg
     3121 tccgcgccgt cgcgcgggag ctcgatccgt agacacacgt gttcgtgctg cccccaaagc
     3181 cactttgggg gcgtacggac tcatgaggag acggtcagcg cccagctcgc gtcgatgccg
     3241 aagtagagct gcctgttctc gtcggagccc atttcgccga tgcgctggac ttcgacgtgc
     3301 atcagctgat cgcccgcggt cggggtgcgc agcgtgtacg cgtacgtctc gcctgcgcgg
     3361 aaaagggatg agcgcgcctt ctgcacgctg ccgtccgcgg cgcggtaccg gaacacgacc
     3421 agccacggcg cgtccgcgat ctgcttgggc acggagatgc tcagcggctg cccgcctggc
     3481 acggccaacg ctcccgtcgg cctgcactcc tcaagcgtcg cgtcgcacgc cggagacggc
     3541 ccgatgttga ccgtttcccc gtcagcgaag aacgtgacct cggggtcgtg tggcgcggcg
     3601 cagcccgcga gcagcagtcc gcccgccacc agcgaggcga ttccaaatcg gcgcacggcg
     3661 tgagactacg tgggctcggt acccgcccgg cgcgccgggg tggcccgccg gaccacgttg
     3721 agcagggaat tccccttggt cgccaggatc gtctgtacca tcccgagccc caggatcagc
     3781 gagatcacca ggaacccgac ccagaacgtg gtcggcagca acacaccaag cgcgccaccg
     3841 aacacccagc caagctgcag cacggtttcc gaccggccga acgcggacgc ccgtgactct
     3901 tccggcaggt cgtgctggat caccgcgtcc aggctgttct tcgccagcgc ggcggccgtc
     3961 gccgcgatca ggctgacgat cgccatcgtg ccgatgcccg gcaggatcgt ggcgaccaca
     4021 gtggctgtga cacacgcgat cacgcagccg agcaccatct gatcaggccg ggtgaccagc
     4081 aaccgggagc cgatggcgtt gccgccgaag ctgccgatac cggccgcggc cgcgatgatg
     4141 ccgagcaaca acagctgctg gaaggcttgg ccttcggtct ccgcgcggat cgcgaacgcc
     4201 gagaacatca tcaggaagcc ggtcagcact ttgacggttc cgttggccca caacgagatc
     4261 accacgtgct ggcccatcgg ctgacgtttc ggtcttgtcg gcgtggccga cagcgtcgcc
     4321 gggacttcgc cttcggtgac ctcgacccac gccgggatcc gcatgccctg cacggcgccg
     4381 acgacacaga tcaaggcggt gaaccacaac gcgccctctg agtcgaacat ctgcgtcagc
     4441 ccagcggcga taccgccgaa caccatcccg gccgccaagc cgaaaaccgt cagccgggcg
     4501 ttggttttgg acagcgtgat ctcgggcggc aggactctcg gcgtgaccgc cgccttgagc
     4561 accgtgaacg atttggacag caccatcttg ccgagcgcgg ccggatacag cagccacgag
     4621 tcgaagttgg tcgccatcac gatgcacatc agcgcctggc ccgcggaggc tacgcacatc
     4681 gccagcctgc ggccgcgctg gatcttgtcc agtgccggac cgatcacggg cgcgaccaac
     4741 gcgaacggag ccacggtgat cagcaggtac agcgcgatct tgcctttgct gctgtccgcg
     4801 ctcgcggccg cgaagaagag tgtgttcgcc aacgcgacgg ccattgccgc gtcgctggcg
     4861 tagttcagca tcgtcgcgta cgtcagcgac gtgaggccgg acttgtcggc gccgtcagcg
     4921 ttcgcagctc gcttgaacgc gccaaccgct tgctgagtca gctgcttgct gcgcaacgcc
     4981 gccacacgcg tgacggtcag cttcttcggc gcctgcggaa ggccaccacg cggcaaggtc
     5041 gcggcttccg aaccgtgctg cgcctcaggc tgcgggggcg gctgctgctg ccggggcggc
     5101 tgaggaggcc cctcgtcgta gtagtcgtac gggcccgtgt ggccggtcct gggcgccgga
     5161 tagccgtccg gaccatatcg ccccgacggt ggaggcagcg gctgctcacg acggatcggg
     5221 gtggtctggc ggtgctcctc aggaagcgga ggagggggcg gaggcggcgg ctgccgccgc
     5281 gcgggcggtg gtggctgtgg ttgtggctgg ctgccgaact gcttgggttg gcgcgcggtc
     5341 cacttacggc ctttggaccg gcccttggca ggccgatccc cgccttggtc gtcagagccg
     5401 gaacgaagca cccttccatc ctgccgtaaa gccgttcggc ccacacaggg agatagctac
     5461 gaggccgtga cgaatttcac ccggaacatc ttcggccaca acttgcccgt gaccaggaac
     5521 tcgtccgttc cagggacagc ggcgatcccg ttgagcacat ccgcacccgc gcgttccgcc
     5581 gggctcagca gtccagcgag gtcaatggag gcggtgacgg ccccggacgc cgggtcgatt
     5641 cgcacgaccg tgtcggtctg ccacacgttc gcgtaaaccc cgttcgcggt gcactccagc
     5701 tcgttgagct gggtgaccgg gtcgttgccc gaccgcaccc gcacctcacc gatcgggtcg
     5761 aaggtgtccg ggtcgcggaa ggtcagtttg tccgtgccgt cgctcatcac cagccgctgc
     5821 ccgtctcggc acagccccca gccctcgccg gtgtacggca cgcgcttgac ctcggcgagc
     5881 gtctccttgt cgcgctggat cgcgacgccg tccttccagg tcagctgcca gattgtggac
     5941 ccggaaacgg tcacgccctc gccgaacatc ggcgacggga gatcgacctt cttctccacc
     6001 cgtgcggtct gcgggtcgac ctcgcgcacg ctggactcgc cttccagccc agtgccttcg
     6061 taaagccggt cgccgtccag ttcgaggccc tgcgtgaacg ccttcgggtc gtgcggcagc
     6121 accgcgagca cctcggcccg cattctcgct ggttgcgcct ggccagccgg tgcggtccca
     6181 gtgccgctct cagtgccaca tgaagccgct aatacgcagg ccgcaacaac aagaagcacc
     6241 ttcacgccgg aagggtgaca cacgtggtgc acaatcttcg tgatgagcac gacgcccgta
     6301 ccagaactcg ccctcgcagg cgtggtggag caagcgcgcg ccgccgcccg tgaagaagcc
     6361 ggtgacgagg tcggcgcgca cgtcggcgtg cagccggaag acgaggccgc ggtcacgcac
     6421 ctcttcgagg ctgacaaagc cggctatcgc ggttggcact gggccgtgac ggtggccaac
     6481 tccggccccg ggaccaaggt gaccgtcagt gaggtcgtgc tcgtgcccgg ccccgacgcg
     6541 ctcgtggcgc ccgcatgggt gccgtggcag cagcgcgtgc aggccggtga cctcggtgtc
     6601 ggtgatctgc tgccgacctc cccggatgac ccgcggctcg tgcccgcgta cgtgcagtcc
     6661 gacgacgagg cggtcgaaga ggtcgcacgc gagatcggcc tcggccgcgt gcgtgtgatg
     6721 tcccgcccgg cccggttgga cgcggcgtcg cgctggcagg acagcgagtt cgggcctcgc
     6781 tccgacatgg cgcgcagcgc gccggagcac tgcggcacgt gtggcttcta cctgcaggtc
     6841 gccgggtcct tgcgggccgc gttcggcgtc tgcggcaacg agatctcccc ggcggacggg
     6901 cacgtggtgc acgtccagta cggctgcggc gcccactcgg agctgcggat cgaccagggc
     6961 tcgccggtgc tcgtggccga tttgatctac gacgactcac tgcttgacgt cgagcgggca
     7021 ccggcggagt gaccgaagat ctgctggcag gatcgagcat gaacacggat ccgttcggta
     7081 cccagcgctt acgcgaggca gtgctggcag cctggagtgc ctcgccaacg cggttccgtg
     7141 aggacgcgaa cgccgaggaa gacctgcggt taggtgcgta tcgcgaccgt ctgctggtcg
     7201 agctcgccca gaacgcggcc gacgcggccg gtttcggcgg acgactccgg ttgtccattg
     7261 tggacaatga gctgcgagcg gccaacacgg gtgcgcccct cgacgcggag ggcgtcgcgg
     7321 cactggcttc gctgcgtgcg tcggcgaaac gggacatcct cggcaccgtc ggccagttcg
     7381 gcgtcggctt ctccgccgtg ctgtcagtga ccgacgagcc cgaagtggtg tcgaccaccg
     7441 gggcggtccg gttctccgcg cggcggaccc gtgagatccc cgagatccag gaccacgtgg
     7501 ccgcccggtc cggccaggtc ccggtgctcc ggatggtctg gccgactgat tccgtcgtac
     7561 cggaaggctt cgacaccgag gtacgacttc ccctgcggcc ggacgtcgac catgccgcgc
     7621 tgctggagaa cttccgtgag caggctccgg acctgctgct ggcgttaccc ggcttggcgt
     7681 cgatcgaggt cggcggatct gtctggacca gcaccgactc tggcgacacg gtcgtactga
     7741 ccggccccga gggcactacg cgctggatgc tgcgtcgggc tacggggaag ttgtccgaca
     7801 cggccgggct cggcatggag accagcaccg agtggatggt ctgctgggcc gtcccggtga
     7861 cggaatccgg tgtgccgcaa ccgttgaccg aggacgtgct gcacgccccg acacccaccg
     7921 acgagcggct ttccttgccc gcgcggctgc tcgccagcct gccgatcgag gcatcccgcc
     7981 ggcacgtgat gtcctcgccc gccgtgcagg aggtgctggc ggaagcggcg aagctgtatc
     8041 cctcattggt cttcggcgtc ccggccatgc accgcacggc tcttgtgccg gttcccggct
     8101 tccctcggtc cgatgtggac gctcagctgc gtgacctgct gatcgccgag ttgcgcacgc
     8161 aggcttggct gccgggggtc accgagtcgt tgaagcccgc gtccgcccgg gtgcttgaga
     8221 tcccttcgga cgccttggct gatctgctct ctgacgtcgt gccgaatctc gcggcagcgc
     8281 agctcgcggc tcctgagcac gcacacgcgt tggcggcgct ggagatctcg cggctgcgga
     8341 tccccgagat cgtcgcggcc ctgaccggta tcgaccagga accgtcgtgg tggcggcagg
     8401 tctacgcggc catcgcgccg ttcgcggaga acgacagcgc gatccgggac aacctcagcg
     8461 gtcttcccgt gccgctggtg gacggccgca cactgcccgg cccgcgcggc acattgctcg
     8521 ccgacgagcc ggagttcttg tccgacttgg atgttccggg gctgcgcctg gtccacccgg
     8581 cagccgcgca tcctttgctg gaacgcctcg gcgcccggca cgcgggtgct gccgagctgc
     8641 tggacgcttt gcaggaggcc gtcgagcgga gtgtcgccga cgcgtcagcg ggcctgatcg
     8701 tgtccggact ggcgcatgcg gtgctgggcc tggtcggcca ggccggtgga cgtccgtggc
     8761 tgaagtcgtt ggcgcttccc gattccgacg gtgactggcg ggccgcggac gaactggcgc
     8821 tgcctggttc gcggttcctt gaggtcctcg atccggactc gccgttgggc ctgcttgatc
     8881 ccgagttcgc cgagcgctgg tccgcggacg tgctgtcggc cgtgggagtt ctgaccggct
     8941 tcgcggtgat cgtggacgag gaaccgatcg gcccggaaca cgacctcgcg gacgaggacg
     9001 aatggtggtc gttcggcacc gaggagccga aacgagtcgt ggccgtccgt gacctcgacc
     9061 tggtcgccga cgacaagtgg cccgacgcgc tgcgcctgct cgccctcgaa cccgcgacat
     9121 ggcaagcgtt gcgggaaccc ggtggctaca cggcctggtg gatctcgcgc tacgccctgc
     9181 ttgacggccg tgcaccccgt ttctggcgga cagcatcagc gcacgacctc gtcggcctgt
     9241 acgacccgct gcccatcgag ttgggtgatg agctcgccgc ggcggccgga gtccgtaccc
     9301 acctggagat caaggacgcc tcggacgccg aggacctgct ggaacgcctc ggcgacccgg
     9361 ccaggtccgt ttcgcacggc gtttccttgc gtgcccacgc ggctttggcc ggatccgtcg
     9421 atgtctcctt gctcgacgcc ccggaacgtg tgcgggtcct gtccggcgag gccgtcgatg
     9481 cggaggactg cgttgtcctt gacgcccctt ggctgctggc cgtgctaccg ccgaaccgcg
     9541 ttgtcgccgc cctcgacgac gatgccgccg agcctctggc agagcttctg gacttgccgt
     9601 tggcctcgga gtccgctggt gatgtcaccg gcggtgagct cgtcccatgg gccgagttgg
     9661 gtgccgtggt cgtcgccgct gagctgctgg gcttcgagct gccgctcgaa ggcgtgatcg
     9721 tccacgacca gctgaccgcc aacggccagc gcgtgcactg gtgggtcgac cggcagaacc
     9781 gcgtgcactg cgaggacacg ccggacggcc tggcccgcgc gctggcgtgg gcctcggacc
     9841 actggatcga ccggcacgtc atccacgcca tcctcgaaga ccccgatccc cgcactgtcc
     9901 tggcgtagcc cgggaaaggt tcccggctga cccgggaaca gctccggggt cggcgggcac
     9961 ggtttcgcgg cactctctcc atgtcgagag ggggctgggg ttgccgagtg atccactgtc
    10021 ggtcgccgtc gaagtggcga cccggctgcg ggacgccgcg gatgacgttg acgcgaattg
    10081 cggcatcgcg atgctgttcg acgagctgga ccggatccag cctggccgtg gctgggcact
    10141 cgcggcgaag gacaagctcg ccagtgccgt ccgggtgatc gagcagaccg gcaaccgcag
    10201 tcctcggctg tacaacggca tcggcacgtt ggggctggcg gcgtggcgcc tgtcgcgtga
    10261 tggcaagcgc tatcagcagg tgcttgccga ggtcgatcgt tgggtcgtcg accgtgcttc
    10321 ggccgatggg cgcgcgttgg cggagcggcc gtgttccggc ggccgtccga ggaacggtac
    10381 atcgaccact cgccgggcct gtgccacgga atcgccgggc tgctgatgat cacgctgcga
    10441 ttcgtccgcg ccaccggaca gttcaaggct gacgccgacg cgctcacacg gtaactcgtg
    10501 acgatgtacg acccagcacg ccgctatggc tacgaattcc tgggcgacga cggcacttgc
    10561 atcgaagacc ggccggaatt cctcgacggc gcggcaggag tggcgctcgc gctgctcgcc
    10621 gcgacaactg agcaggaccc ggcgtgggac cggatgttgt tgttgtcctg aaaggagaag
    10681 caatgcccat acgggatgag ttcgacctgg acgtgcgact cggcgaaccg atcgaactcg
    10741 gaatcatgcg cggcacaccg ccgaccacag aacagtgccc cgattcgcac gcggtgacgt
    10801 gcggcggccc ctgctgcgat cgcagcttca gctgcctcta ggtgtcccac cggcaactag
    10861 gccctagttg tcttgaacgg taaggagaaa catgaccgct tcggtgatcg acgatttcga
    10921 cctcgacatc aggttcggcg agccgatcgt gccgcagacc tcgcccatgg cgggcaagac
    10981 gtcggacttc gagtcatgcg agaccgaatc gcactgtggc acttgcggtt cgacgtgtac
    11041 cacgacgacg tccagaaact gctgatgacc gggtaccggc cgctggactg gctgatggtg
    11101 cgggcgccac tgctgcccgt cgagcgctgt ctcggccagc accacttgat caccgggtgc
    11161 gcagggcgct cgccgtcggc gcaggcgact tgtggcgtgc ggtcgaacgg cagcagccca
    11221 gcgaccgggc gctgccctcc cttgatctct cggtgttcgt gctcgcgttg tcaccggaag
    11281 cggtcgacgc gggcgatttc cagatgatgg tcggcccgaa cttcggcgcc tccgcggcgg
    11341 gccgggtact cggccggttc ggtgacctgc tcggtgaaca ggcgcgaacc gcattgcgat
    11401 ccgtggccga cgccgaggcc gtcgtgcgac ccgggcgggt gtgggccgag gtgaactacc
    11461 tgcctcgcaa gggccggttg ggcaacgtcg cgaccagggc gctggttcgt gatcacgagc
    11521 tggtcctcaa tacgacgcct ggtggcgagc ggatcatccg ggccgcggat ctgctggtcg
    11581 gcgtccggga caaccggttc gtcctgcgct ggtcggtcac cgggcacgag gtcgtgccgt
    11641 gttccgggca catgctcaac ccgcgttccg gatcaccggt gatccagttc ctcgacgacg
    11701 tcagcaggga cggctacgcc atgcccagct cgttcgactg gggaccggcc gccaacttcc
    11761 cgttcctgcc acgggttcag gccggccgga tcattctgac gccggcaagg tggctgctgc
    11821 gcgccgagga attcacccag caatggcggg aacgctggca agtgccacga cacgtctacc
    11881 tctccaccgc cgacaaccgg ttgctgctgg acctggccga ccccgatcag ctgaagcagt
    11941 tgccggacaa ggggttgatg gtgctgcagg aggcattgcc cgcgccggat caggcgtggc
    12001 tgcccggcag cgaggggcgt tacgtcagcg aattcgtggt tccgctcatt cgtgaagaaa
    12061 tcgggcctga gccggaaccc gcgcggcaaa tcccgtcagg caggcggatg cggccacctg
    12121 gcagcgactg gctgttcgcc aagctgtacc acctgccgac gttcgagaac gatctcctca
    12181 ccggcccggt caaggacttc tgcgatggca actggttctt catgcggtac gtcgaccccg
    12241 gcccgcatct gcggatccgg tggaccggcg acccgcggtg gctgaccggc gagctggcgc
    12301 cacgggtgct ccggtggtcg gcggaattgg tggagcgggg ctactgcaca cgtgtggccc
    12361 ttgacacata cgaccgggag ctcgaacgtt acggtgggcc aacggcactc gaggccgccg
    12421 agtcgctctt cgcggccgac agctcggcgg tactcgacct gctgcgcctc aacgacatcg
    12481 accggacgct gctcgggatg tacacagtgg acgatctgct ggtcgggctt gggctgaccg
    12541 aagacgaacg actcggcaac taccggctcg cagtggccga ccggcgcgcg acggcggacg
    12601 agttccgcag ccgccaggtc gaactgcgcc gcgcacctct gcggcgaggt acggcatgag
    12661 tgcgccgttg gtcggcgtcg acgaggtcga gcttcccaag tggacagaga tcgaccagca
    12721 ggtggccaac gcgggcctct ggcacacctt gcgcgccctg ccttccgggg tgagcatcgt
    12781 gctccgcctt gcgtggcagg cgtcgaagcg gctcacactg ctgtcggcca tcctgtcggt
    12841 ggccgccggt tgtgccacgg cgttcggcct catcgccacc gcggacgtac tgacgactct
    12901 gctggcacaa ggccccactc cgacgcaggt tgtggcttct ctgccgtcgg ttgcccttgt
    12961 cgtggcgtcg ttttcactgc gggcgttgct tgattcggcg agcacagcgg cattggcgtt
    13021 gctgcggcca cacgttgagc agaccgcaca ggaaaccgtg cacgctgcgg tctcgcaggt
    13081 cgaactgatc gccttcgagg acagcgacta cgcggacttg ctgcggcagt gcatgacagc
    13141 gggcgtacgc agcatcgagt cgagtatcaa ggcgatctcc ggcatcgggg gttcgctggt
    13201 gtacctcatc gcgtcggtgg tctcggcggg tgtgttgcat cctttgctcg caccggtcgt
    13261 gctcatcgcc gtcatcccga acatgtgggc gtacgcgcgt gccgccaaac tggcctacgt
    13321 ttcctatctg gcaatgcttt cccggtcccg gcggctcagc atcgcgagcg agctgctcac
    13381 cgctcgggaa accgcggccg agatgcgcgc ggccacggcc cgcctcgcgc tgctggagga
    13441 ataccggcgg atcagcacga tgctcaccga cgaagcggtc cgggtcgagc tcaagcagac
    13501 cagggtccgg ctgatcggac ggatcatcgc gggtgtcggc actggcgctg gttacgccgt
    13561 gctcggcgta ctgctgcacg cgggttggct ggcgttgccg ctcgcgggcg ctgcggtggt
    13621 ggccatgcga gtggcgacgt ccgcgttgat gaccacgatg atgggcgtca agaccctcta
    13681 cgaggacacg ctttacgtga agctgtacac gcggttgctg gaaatttccc gggcccgcac
    13741 ccggtcgccg gtcgcggccc aggcaccggc tccggccgtg atcacactgg aggaagccag
    13801 tttcagctat ccgggccagg acgcaccggc gcttcgcgac gtgtccctga ccatcaccaa
    13861 gggccaggtc gtggcgctgg tgggggagaa cggttcaggc aagagcaccc tcgccaaact
    13921 gatcaccggc ctgtaccagc cgacgggcgg ccgcgtctgc tgggacggcg tcgacctggc
    13981 ggagttcgac gaggagtcgg tgtaccaaca gatcgcgttg gtcctgcagg accccgccag
    14041 gtggccgatg accgcgcacg acaacatccg gatgggccgg atcgaccggc gggacgggat
    14101 gtcggtggcc gaagcggcca gggagtccgg cgcggaagac gtgatcgccg aactgccgaa
    14161 cggctaccag accctgctgt cccggctgtt cagctcgggc cgggacctgt ccggcggcca
    14221 gtggcagcgg atcagcgtgg ccagggggat ctaccgggac gcaccgatcc ttgtggtgga
    14281 cgaacccacc gccgcgatgg acgccaaagc ggagcacgcc gtattcgagt cgctgcgcag
    14341 gctcggcggc ggccggacca cgatcctgat cacccaccgg ctggcgaacg tccagcacgc
    14401 agaccagatc gtcgtcctcg accagggcaa actcgtcgag cagggcacgc accacgagct
    14461 catggccctg ggcgggacct acgcgggcct gttcaccctg caggcctcgg cctacacccc
    14521 ccgcacataa cccgcgtgtc cacctttccg acacaccgaa acgcacattc cagcaccttg
    14581 agatgcgcgt accggcacca caagtcacgc ggctcgatgc cgcaagggga atttcatggt
    14641 gccgcaatgg tggacacggg gtgccggaat ggtggacacg gcgcccatcc ccgggctata
    14701 tcccctgctg ggccgtcttc gatcctttgc gggcggcgga gcgctgccag gtcatgatgg
    14761 ccatgccgat gccgccgagt accacgccgg tgaaggccgt ccacgccagg atgctggggc
    14821 cggtgaagag ggcgacgacc aggacaccga accagacaat ctcgccgacg acgacgatcc
    14881 ggaacagatc caccagccgc gccgggggcg gcgggggtgg cggaagtgac tttccggttt
    14941 cgcctggcga ttcgggttcc tctgtggacg ccacgtgatg caggctaccc gcatggccga
    15001 caccaccagc cgccgcggcg ctctcgaccg cttcttcaag atcagcgagc gtggctcgac
    15061 caccggacgg gagatccggg gcgggctggt cacgttcgtg acaatggcgt acatcgtcgt
    15121 actgaacccg ctgatcatcg gcagtttcgc ggcagaggga ccgtccgcgc accgcgatgt
    15181 cctcggcgac atcctgccgg tcagccaggt cgccgccgtg accgcgttgg tcgccggtgt
    15241 gatgaccatc ctgttcgggc tgatcgcgaa ctacccgttc gcgctggcca ccgggctggg
    15301 gatcaacagc ttcgtcgcgg tcacgctggc gccgcagatg acgtgggccg aggccatggg
    15361 cctggttgtg ctgaacggca tcgtcgtgat ggtgctcgtg ctgaccggcg tgcggacagc
    15421 cgtgttcaac gccgtgccgc agccgctcaa ggccgcgatc gccgtcggga tcggtctgtt
    15481 catcacgctg atcggcctgg tcgacgccgg gttcgtacgc aggattccgg acgcggcgaa
    15541 cacgacggtc ccggttggcc tcgggatctc ggggtcgatc gcgtcgtggc cgacgttcgt
    15601 gttcgtggtc ggtctgcttg tcaccggcat cctggtggcc aaacgcgtca aaggcgcgat
    15661 cctgatcggc gtcctgttct ccacggtcct tgccatagtg ctggaggcga tcgtcaaggc
    15721 cgggccttca cagggcgtga acccgaaggg ctggaacctg ggctacccgg cgatgcctga
    15781 gcaagcggtt ggtctgccgg acttgtcgtt gctcggtgag ttctcgttcg gcgcgtggag
    15841 ccgggtgccc gcgctcacgg tggtcctgct gctgttcacg ttgatcctca ccgacttctt
    15901 cgactcggtc ggcacgatga ccggtctggg caaggaagcc ggtgtgatcg gcaaggacgg
    15961 gcagctgccc ggcgtcggca aggcgctgtt cgtggactcg ctcggggcgg tcgccggtgg
    16021 tgccgcgtcc agcagctcga acaccgtcta catcgaatcg gcgtccggta tcgccgaagg
    16081 cgcgcggacc ggcctggcca acgtggtcac cggcctgctg ttcatcgccg cgatgttcct
    16141 cacaccgctg taccaagtcg tgccggtcga ggcggcggcc ccggctttgg tgatcgtcgg
    16201 cgtgctgatg atggcgcaga tcaaggagat cgacttcacc gacttctcga tcgcgctgcc
    16261 cgcgttcctg accattgtgg tcatgccgtt cacgtactcg atcgccaacg gcatcggcgc
    16321 aggcttcatc agctacgtgg tcctgaaggt catttccggt cgcgccaaga gcgttcaccc
    16381 gctgctctgg gtggtcgcgg tcgcgttcgt cgcgtatttc gcggtcggcc cgatccaggg
    16441 cgcgatcggg tgacgctccg tcacatcgtc ccggccggct aattcataag gtatgctaag
    16501 tatgtgtctg gttccgccga cgagcactcg ctgaccagcc gactccggct gtcggtgatg
    16561 cgtctcaacc gtcggctccg ggcgcaacgg acaaacgcgt cagtcacgtt gagccagatc
    16621 tcagcgctgt cgagcctgca caagtgcggc ccgatgacgc cgggtgaact ggccgcgcgc
    16681 gaaggcgtac agccgccctc gatgacgagg gtgatcgccg ccctcgagga cttgggctac
    16741 atcagcaaac gagcccatcc caacgacggc aggcaagtga tcgtcgagct gaccgagcgg
    16801 gggctcggtt acatcgaggc cgacgtggcc gcgcgcgagg cgtggctgga cgcacgactg
    16861 tccgaattgg acgaatccga gcgggagctg ctgtcccgcg cggccgagat catcgacagg
    16921 atggcggggc aataaagagg tgctgaccgg cgcgggtggg acccgagaga agaagccaag
    16981 caacttcgac tcagacctac ccccaccgcc ggagcagcca aagcaaggca ccttctcgtc
    17041 cttacgcatc cgcaactacc ggcttttctt ctccggccag gtcgtcaaca acgtcggcac
    17101 ctggatgaac cggatcgccc aggactggct ggtcttcacc ctgaccggaa acaacccggt
    17161 cgcgctcggt atcgcggcgg cgctgcagtt cgcgccgacg ctcttcctct cgctctacgg
    17221 cggcgtcctg gccgaccgcc tggacaagcg caagctgctg atcgggctgc aggccgcgat
    17281 ggcgggctgt gcggtgatcc tcggcgtgct ggacgtctcc ggatgggtgc agctctggca
    17341 ggtctacgtg atctgcttcg tgttcgggtg cttcaccgcg gtggaaaccc cggtgcggca
    17401 gtcgttcacc agcgagatgg tcggcatcgg cctggtcacc aacgcgctcg cgctcaactc
    17461 ctcgtcgttc aacctggccc gcgtggtcgg cccggcggtg gccggtctgt tgatcatctg
    17521 ggtcggtacc ggcatggtgt tcctgatcaa cgcggtcacc acgatcgcgg tgatcaccgg
    17581 gttgctgctg atgcggccgt cggaactgca ccgcgggcct gcggtggccc gcgcgaaggg
    17641 ccagctgcgg gaagccttgc gctacgtgcg cggccgagcc gacctggtgg ccgtgctgag
    17701 cctggtgttc tgcgtgagca ccttcgggat cacgttcttc accacgctgg cgatcatggc
    17761 ggcgaacgtc ttccacaagg aagccgacgg ctacggcctg ctgtcgacca tgctcgccgt
    17821 cggcaccctc agcggtgcgc tgctcgccgc ccgccgcagt gtgcgcggca agccgaaact
    17881 gcggatggtg ttcggttcgg cgctcgtgtt cggcgtgctc gaaatcggcg ccgggctgat
    17941 gccgacgtac ctggcgttcg cgatcgccct tgtgccggtc ggcgtggtcg tcatgacgtt
    18001 catgaatacc gcgatcacga ccgtgcagct gtcggtggag caggagatgc gtggccgggt
    18061 gatgggcctg tacatgctgc tgttcctcgg cggaaacccg atcgccgggc tgctgaccgg
    18121 ctggttggcc gaccagttcg gcggccggtc gacgttctac gtcggtggtg cggtgtcgat
    18181 catcgccgcg gtcgtgctgg gcctgatcct gcgctggcgg gctagtctgc ctgaaaggcg
    18241 atcggcagcg cagggggaag ttcgtgggac tgttcggcaa gaagaaggca caactgccca
    18301 gacgtgaggt gatctggggc cactgctacg acgacgacct gctcgacgcg gcggaagcgg
    18361 aactgctgga gggcaagctc aacgcggcgg tcaccgtgct cgtggacagc agggagaacg
    18421 cggaggcgcg gagcctgcgc ctgggcaggc tggggcaccg gctggtcggc agcgccgacg
    18481 agatcgccga actggccgcg cagcaccgtg acccggaact gatgctgctg gccggggacg
    18541 cgtacatcgg tgaagcgtgg gcgatccgcg gcagcggctg ggcctcgtcg gtcggcgagg
    18601 accgggccaa gatgttcctc acaacgctgg aaaaagcccg cggcccgctg gaagcggcgg
    18661 cggagatgct gcctgcggac gccacaccat gggcgcagat ggtcaccatg ggcatgggcc
    18721 tcggactgga tcggtccgaa caggacgcgt tctgggcgga gacggtgaaa cgcgcgccga
    18781 cgctgtaccc agcacattgg acacgcctgc aggtgctggc cgagaagtgg tacggctcgc
    18841 acgaggagat gtcccagttc gcgatcacca cggtgaacaa cgccccgcac ggcgacccgg
    18901 tgaccgcgat gatcgtggtg gcgtacttcg aggtgttcat ccaggccaaa gcccgcgcgg
    18961 agcgggaagt gcgaaagccg aacctgcgcg cgatggccga aggcgtgttc aagaagagct
    19021 accagaacat ccaagccgcc tccaaccgct ggatgcaggc cgaaaagccg cacccgcgcg
    19081 cgttcgaggc gcacaactac ttcgcggcgg catgcggcct ggcgggcgat ggggaccggg
    19141 cgttcatgca cctgttcggc atgcgggacc ggctgatgag caggccgtgg aacctgttcg
    19201 cggacgagcc ggaagaggaa taccagagca tggtccagaa gtactggcgc gccgacctga
    19261 cacagggcct ctgaatagat gagagccccg gccggcgggc cggggctctc actgttcccg
    19321 aactgactgc cgctcccacc acgaagcgga caggtatgag gttagcctac cctcactagc
    19381 tccgcaacat cgacatgcac cgagtgcccc gaaagtggca ccgggtgtgg ctggaacacg
    19441 tgaagaagcc ctcggccgtg ctggccgagg gcttcttcga gtaggcagct tcgcttgtcg
    19501 gagcatccgc tgccaggctt gaaaacgatc acgcctgcgg cacgcgcagg ccgttcagcc
    19561 cgttgcgggc gtcgacgaag cgctggttga cgtcctccca gttgacgaca ttccacagcg
    19621 cgttgatgta gtccgccttc acgttgcggt actgcaggta gtacgcgtgc tcccacacgt
    19681 cgaacgccag cagcggcgtg gtggcgatcg agaggttcgc gtggtggtcc ttcagctgct
    19741 gggtcagcag ccgctggccg atcgggtccc aggacaggat gccccagccc gagccctgga
    19801 tcgtcgtggc ggccgcgttg agctgggcac gcagcttgtc gaacgagccg aagaactcgt
    19861 cgatcgccgc ggccagctca cccgtcggct tgtcgccgcc gttcgggctg aggttcttcc
    19921 accacacctg gtgcagcgag tggccggcga ggttgaacgc cagcgtggtc tccaggccga
    19981 cgatcgagcc gaactcgccc ttgtcgcggg cttcgtcgat cttctccagc gtgtcgttgg
    20041 cgcccttgac gtacgcggcg tggtgcttgc cgtggtgcag ctcgttgatc tcgccgatga
    20101 tcgccggctc gaggtcgccg tagtcgtagt ccaggtccgg caggacgtac ggggccatcg
    20161 gccctcctta caggtaggcg ttgcaagtat ctgctacttg caacctactc gcaataaggg
    20221 ggccggctcg aagcgaccat gatcacctca ggacatggaa tatctgggca tgtcctcggc
    20281 gagtgcggcg aagacggcca cattcagctc gtacgcccga aggctctcca cgatgactcg
    20341 cttgcgctcc tcggcgtccc atggcgcgga gttcagcagc gcgcggtagt tgtcccggaa
    20401 tttgggcgca ctcgggatct ggtcgaagac gtagaacatc gatccggggc cttcgacccc
    20461 gtgcagcttg cgcagcctgt gccggatgac ctggccgccc gcgatgtcgc cgaggtagcg
    20521 cgtgtagtga tgcgccacga actcgcctga ccacgagaca gaacggatcc gtgcgcagta
    20581 ctcggtagtc gccgggagcg gctcgacgac cgactcccac gcaggtccga agtagtacgc
    20641 catgtcctca cgcaacgcgt cgcggcggtt gagctccgag aacacgaact tgcccgcgat
    20701 cgggtcgtcc cgcatggctt cggcggtgtc ttccagtgcc gagtacacga agtacagctg
    20761 gctggccagc tggccgaacg cgtcgactga caactctccg cccagcagtg ccgagatgta
    20821 gggggagtgg ttggcctgct cgtgcgcggg catcgtcgca gctcgcaggg tttccgagaa
    20881 cgtcgggctc atgctcacgt ctcctttatc tgacaccgct gtcagaaaag gataggtgat
    20941 ctgtcgcagt taggccaccc taactccgac ggctcggaga atgaagcgca cggcggtctc
    21001 aatcgtgttg tcgagctcgg cccccgcgtc cacgacctca cgggacgcca ggctggccgt
    21061 gatcatggtg atcagcacat ccacgtcctc gtcgaccatc tgccccgaag cgatcccgga
    21121 ttccaggatc gagcgcaact cggcggtgat cgggtcgacg tgctcggcca tccgctcgta
    21181 cgcctccggc gacagcaagg cgttcagttt cgcgcccggc ggcgtgtgcc gtccggcgag
    21241 cacgcgcagc tgcatgcgga cgaacacagc cagcgcctcg accgggtcgg acaccgcggc
    21301 gagcgcttcc cgcagccgga tgacgtactg cgaggtctcg tgttcgacga acgcgaccag
    21361 cagtgattcc cggtcaggga agtggttgta gatcgcggtc cggccgaccc cggccgccga
    21421 ggccaccccg gacagcgtga tcgcgtcgaa gccacgggtg tagagcagcg tgcgcatcgc
    21481 gtcgaacacc ttcgcgcgca cctgcgagcg gtgctcggcc agcgactcgc cgaggatttt
    21541 cggcattcct cgacattagc ccactggcca ggtgtggacc ggttcaccag tgtgcatcag
    21601 ctcgaggtac gcccgcagca tgccgagcag tgccgcgtcc cggttcatgc cgcgttgctc
    21661 cagcctggcc acggtctccc gttgccagga agcgccgttg cgccgggcaa cgcaccgctg
    21721 ctcgatgatg cccaggtaac gctcccgcgc cgcgtccgac acgccacagt cgcgcaaacc
    21781 ctcgtgtgcc atgggaagca gacgccgcag cacgagttcg tccggtggga tccagccgat
    21841 gcccggccag tacagctggg cgccgaggcc gtgccgggcc gccgagtaca ggttctcctc
    21901 agccgcctgg aacgacatct gcgtccagag tggacgatcc tcgttcacca gtgcgcgttg
    21961 cacgccgtag aagaacgcag cgttggcgat gaggtccacc acggtcggac ctgctggcag
    22021 cacacggttt tccacacgca ggtgcggcac gccgtcgacc acgtcgtaca ccgggcggtt
    22081 ccaccgccac acggttccgt tgtgcacccg cagttcccgc aatgcgggcg cgcggccttc
    22141 ggccagctcg gtcatcggat cctcggggtg cacctcgggc agcagacccg ggaagtaccg
    22201 gacgttctcc tcgaacaggt cgaagatgga cgtgatccac cgctcgccga accacaccct
    22261 cggccggacg ccttggttct tcagctcttc cggccgggtg tcggtggcct gctggaacaa
    22321 cgggatcctg gtctcgtgcc agagtgcctt gcccagcagg aaaggcgagt tcgcggcgag
    22381 cgcgacctgt ggcccggcca ggcattgcgc cgcgttccag tgcgcggcga agtcctcggg
    22441 tgcgacttgc aggtgcagct gcgcggacgt gcacgccgct tccggcagga tcgtctccgc
    22501 gtagctgcgc aaccggtccg ggccttggcc cggcatcggc tcgccttcca tgttcagcag
    22561 catttcctcg ccgcgtgcgg cgaagatgcg ctcgttcagc acggcgtacc gttcgctcgg
    22621 ggaaagccac cgcgcgtcga aatgctcttc ccgcaatgt
//
