LOCUS       NZ_FWXV01000009        24899 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Kibdelosporangium aridum strain DSM 43828, whole genome shotgun
            sequence.
ACCESSION   NZ_FWXV01000009
VERSION     NZ_FWXV01000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium aridum
  ORGANISM  Kibdelosporangium aridum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900176515.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:02:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,283
            CDSs (total)                      :: 11,193
            Genes (coding)                    :: 11,032
            CDSs (with protein)               :: 11,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 3, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 38 of 161
            Pseudo Genes (incomplete)         :: 135 of 161
            Pseudo Genes (internal stop)      :: 6 of 161
            Pseudo Genes (multiple problems)  :: 17 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:58:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 123730
            Orig. end                         :: 148629
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FWXV01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24899
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24899
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24899
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[<10000:14899](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<10001..14899)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    901..914
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.75"
                     /tool="antismash"
     misc_feature    complement(906..919)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     misc_feature    complement(1007..1020)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.31"
                     /tool="antismash"
     regulatory      1076..1157
                     /bound_moiety="S-adenosyl-L-homocysteine"
                     /db_xref="RFAM:RF01057"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01057"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="S-adenosyl-L-homocysteine riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            1173..4775
                     /gene="metH"
                     /locus_tag="B9C43_RS38805"
                     /old_locus_tag="SAMN05661093_07915"
     CDS             1173..4775
                     /EC_number="2.1.1.13"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008705 - methionine synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032855.1"
                     /locus_tag="B9C43_RS38805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07915"
                     /product="methionine synthase"
                     /protein_id="WP_084432182.1"
                     /transl_table=11
                     /translation="MSKSLQDLLRERVVVLDGAWGTMLQGAGLTAADYRADFIADDHPK
                     DVTGDPDLLNLTRPDVILDVHRQYLAAGADITTTNTFTATSIGQGDYALQALVHDMNVR
                     GAQLARQAADEAGGKFVAGSIGPLNVTLSLSPKVEDPAYRAVTFDEVYASYAEQIKALA
                     EGGVDLLLIETIFDTLNVKAAVAAAKDVAPHLPLWISVTIVDLSGRTLSGQTVEAFFSS
                     IEHADPLIVGVNCSLGAAEMRPHVADLSRLAGTYTASHPNAGLPNAFGGYDQTPDETAA
                     LLKDFVEQGMVNIVGGCCGTTPAHIKKIAQAVEGLKPREIPAIHPKTRFSGLEPFEIGK
                     DTGFVMIGERTNVTGSAKFRRLIEGKDFQAAVDVALDQVRGGANLLDVNMDADLLDSER
                     AMTTFLNLIATEPEVARLPVMIDSSKWTVLEAGLKCVQGKGVVNSISLKEGEEQFLEHA
                     RKIRSYGAGVVVMAFDEKGQADSTKRKVEICARAYDLLTQKAGFPAEDIIFDPNVLAVA
                     TGIAEHNGYAKAFIDALPLIKQRCPGVRISGGISNLSFSFRGNNVVREAMHSAFLFHAV
                     KAGLDMGIVNAGQLAVYQDIPADLLELVEDVLFDRREDATDRLVAFAETVNGKGTKRAV
                     DLSWREAPVAQRLEHALVHGIVDFIEEDTEEARQDAARPLDVIEGPLMDGMKIVGDLFG
                     SGKMFLPQVVKSARVMKRSVAYLEPFMEAEKEKLRAEGKIDTRHGNGKVVLATVKGDVH
                     DIGKNIVGVVLGCNNYEVIDLGVMVPAATILDTAIAEGADAIGLSGLITPSLDEMVSVA
                     TEMQRRGMKLPLLIGGATTSRQHTAVRIAPAYDGSTVHVLDASRVVGVVSHLLDDGKAA
                     VLDEANRVEQARLREQHEAKERRPLLTIEQARANPERVSFDDLPRPDFTGVRYLEPDLN
                     TLREMIDWQFFFLAWELKGKFPAILDQPVAKELFDDGTALLDQIIADGSFHAQGAYGFW
                     PAHSEGDDIVLDGQLRLPMLRQQTEKPTGRPNRCLADYIAPQGDHIGGFAVAIHGAEDL
                     AAKYEESNDDYRSIMVKALADRLAEAFAEYIHLEARRAWFEPDVEPKLEDLHAERFRGI
                     RPALGYPASPDHSQKKQLFDLLDAEKVGMALTESYAMTPAAAVSGLIFANPASRYFTVG
                     RIGRDQVEDYARRQDVGIEVAERWLRPNLGYETN"
     gene            complement(4760..4987)
                     /locus_tag="B9C43_RS38810"
     CDS             complement(4760..4987)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS38810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_084432185.1"
                     /transl_table=11
                     /translation="MLKRSVFYHPHHVHDAKSRPLAAASPLSLTHSGRLGMRLSQLAES
                     AGARQSSVRVEEAILKLKTGLYDQFLQLVS"
     gene            complement(5025..6038)
                     /locus_tag="B9C43_RS38815"
                     /old_locus_tag="SAMN05661093_07916"
     CDS             complement(5025..6038)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022646.5"
                     /locus_tag="B9C43_RS38815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07916"
                     /product="DUF2891 domain-containing protein"
                     /protein_id="WP_084432188.1"
                     /transl_table=11
                     /translation="MSPLPRTTRLDRQTANRLLDTAVANVQRDYPVHWTRLIAGPEDLV
                     PHRTLHPVFAGSYDWHSCVHQTWLAARLLRHDPDLPGAASAKSVLTSLITPEGCTTEAA
                     YFSTGAGRHWERPYGWAWLLTLDAELAGTAWSVAPLNEVLRANWLTWIQDARFPVRVGT
                     HANTAFAVGLVLDAARATGDTELAEACTSAALRWYFDDAGYGGFEPDAADFLSPALAEA
                     DLMRRVMDGTEFAKWFDAFLPDLTADRWQILREPAPVDDPSGAHGSHLSGLILSRAWAW
                     RSIAESLPSSHRYVSLAREAFEAHSAVGWDYVFGYGYAAEHWLGTFAAYLELGAQS"
     misc_feature    complement(5799..5801)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6095..7483
                     /locus_tag="B9C43_RS38820"
                     /old_locus_tag="SAMN05661093_07917"
     CDS             6095..7483
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800237.1"
                     /locus_tag="B9C43_RS38820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07917"
                     /product="class II 3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_084432191.1"
                     /transl_table=11
                     /translation="MNWTVDVPVDTLPELPPLPPHLRKALDEALAKPAAQQPEWPDQDN
                     VRKVRTLLESVPPITVPAEIDRLHQRLAEVANGEAFLLQGGDCAETFADNTEPHIRGNI
                     RTLLQMAVVLTYGASLPVVKVGRIAGQYAKPRSNPTDALGLPVYRGDIVNSLVATPEAR
                     VPDPSRMIRAYANAGAAMNLLRALTGAGMAGLAMVHDWNKDFVRTSPAGERYEALAAEI
                     DRGLRFMQACGVHDYSLEHTEIFASHEALLLDYERALLRMDVCGEEPKLYDLSSHFLWI
                     GERTRQLDGAHIAFAELLSNPIGLKIGPTTSPELAVEYVERLDPHNKPGRLTLISRMGN
                     HKVRDVLPGIVEKVEASGHKVIWQCDPMHGNTHESSTGYKTRHFDRIVDEVQGFFEVHR
                     RLGTHPGGIHVELTGEDVTECLGGAQEISDTDLSGRYETACDPRLNTQQSLELAFLVAE
                     MLRS"
     gene            complement(7615..9558)
                     /gene="pknB"
                     /locus_tag="B9C43_RS38825"
                     /old_locus_tag="SAMN05661093_07918"
     CDS             complement(7615..9558)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155384.1"
                     /locus_tag="B9C43_RS38825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07918"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_327224295.1"
                     /sec_met_domain="Pkinase (E-value: 1.5e-50, bitscore:
                     166.9, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQERGGLGMATLLEQRYRVDAPLARGGMSAVYRGMDMRLERPVAI
                     KVMDHRFAEDQSFVDRFEREARAAASLHHPNVIAVHDQGFDGDHVFLVMELVDGGTLRD
                     LLVERGRLTVPLALSVLEPVLSALAAAHQNGLVHRDVKPENVLIGKSGVVKVGDFGLVK
                     AMASGNNTSNSVILGTVAYLSPEQVATGVTTARGDVYSAGLLLYEMLTGQPPYVGDTPI
                     SVAYRHVNDDVPPPSLSAPGIPQALDELVLRATRRDPMARPADAGAFLQEVERVRHAIG
                     APLVPIPAAAHGMQTVPRVATDMPTVQTEPVPPAAPTVPGPQGTRAMVRSDLDPPSKPP
                     RSPVEKKKEPPRKRFPIPRWGIAAAVLAVAAIVATIFLTAGPEPVAIPNVVGADKQSAL
                     KRIEDAKLVPTVVESRSDSVARNKVIRTDPPTGTLIPGSGVNVYVSVGPPIVPDVEPGA
                     TVPDVENALRAQDLKPKLSTEEDRFDNNAPKGSVVALSPSPGTQLKLGDEVIMVLSKGP
                     APLKPLPDVRGKTEAEARQLVQEAGYTVTVNTRFDERVDGGRVISTDPVAGTVSEEKKV
                     TLTVSNAVTVPDLNGKRINDAKEQLDKLGLKLELAFGDDRGNRRIFAQGPNPGSRVQKG
                     STVRVAVNFFGS"
     misc_feature    complement(8158..8160)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9645..10013
                     /locus_tag="B9C43_RS57020"
                     /old_locus_tag="SAMN05661093_07919"
     CDS             9645..10013
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657740.1"
                     /locus_tag="B9C43_RS57020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07919"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_160097007.1"
                     /transl_table=11
                     /translation="MSAIPIADDVLDPAVEVLTLREVADRVGRPVSRVQQALRDHQLIA
                     VRRRGELLVPAIFLTDNDEVVKGLPGTITLLVDSGYSPSEILRWLFTADESLPGTPIEA
                     LRGDRGREVKRRAQALAF"
     gene            complement(<10001..10900)
                     /locus_tag="B9C43_RS38830"
                     /old_locus_tag="SAMN05661093_07920"
                     /pseudo=""
     CDS             complement(<10001..10900)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015786942.1"
                     /locus_tag="B9C43_RS38830"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07920"
                     /product="phytoene/squalene synthase family protein"
                     /pseudo=""
                     /sec_met_domain="phytoene_synt (E-value: 3.5e-110,
                     bitscore: 362.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.5e-65,
                     bitscore: 216.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRELDAAGITDPELRAAYAESKAINASHGRTYFLATRLLPIAD
                     RPAVHALYGFARVADDIVDGSLPKSQQTMELLALERTMWDGGQPVLRALADTVRRYRID
                     RRLFSDFLASMRMDLHVKRYETYADLAEYVYGSASVIGLQMLPVLGTVSPQEEAEPYAA
                     ALGEAFQLTNFLRDVGEDLDRGRVYLPMDELAAFGVDRDRLRWARRTGRHDPYIRRALA
                     HMVARTVAIYRRAEPGIELLRPWSRPCVSTAAKLYRGILDEIVAVDYEILNRRAVVPTG
                     QRLRVALPAATKAAGQNAR"
     misc_feature    complement(10238..10240)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10941..12311)
                     /locus_tag="B9C43_RS38835"
                     /old_locus_tag="SAMN05661093_07921"
     CDS             complement(10941..12311)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS38835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_07921"
                     /product="hypothetical protein"
                     /protein_id="WP_084432197.1"
                     /transl_table=11
                     /translation="MIRRGLGTLLVTVLLCAGCTGDEPSPNGPAPAPKLVAADAVAQSI
                     VDLRSAGAVRYNGSLTAPAGDNVTMQVTVTKAGEATGELSVNGLPATVLVVDHTLYLKA
                     GLDFWLKLSGVPDSTAPTVADHWVKAPGVLLGVDIERIFDTETLPGLFGKPLANQTPDA
                     VKRTKVAGQDVLEVPTDAGVLYLGVNPPYGLVRFDLTKSGKTDPTKVRDLAFSVSDATS
                     DMAALYRDLAAKTAELETAYDPFTGVKQGTHKFQNCGVSSCAIVVELTNVGKQAVRVAV
                     KATWTGGGNVIGSCESRVGPLQPSQAGSATCTLSSPQWTQFYRRAQSVPGQHPYGAEWT
                     AMALITPPDPTGLRTLASSAETPVANPQGNQHVYVIRDDAGKDDKQIWKYGVATGPDWR
                     KIPDEQLKFCTAGCVVDEVAATGDPASAHALARQLVDAYRGRVGQCPPAQWVGCSPK"
     gene            complement(12375..13841)
                     /gene="crtI"
                     /locus_tag="B9C43_RS38840"
                     /old_locus_tag="SAMN05661093_07922"
     CDS             complement(12375..13841)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637666.1"
                     /locus_tag="B9C43_RS38840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07922"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_084432200.1"
                     /sec_met_domain="DAO (E-value: 5.3e-14, bitscore: 47.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVTGRTDHVIVVGAGLAGLSCALHLLGSGHQVTVLETGSTPGG
                     RAGRMRIGEYTVDSGASVLTMPGLIEDALAQVGAPMVDLIKLDPAYRAHFADGSTIHVH
                     SDAAAMEDEIRGVAGPAEAVGYRRLRKWLTELYRVERDSFIGANFDSPLDLLGSQLASL
                     VALGGFGRLGPAISKYLSDERLQRLFSFQSLYAGVPPQRALAAYGVIAYMDTIAGVWFP
                     RGGVAAVAEHMAKAASDAGADVRYSCGAAWLERVGSRVTAVRTTAGERISCDAVVLTPD
                     LPIARGLLGLPSRRLVPLQWSPSAVVLHAGVNRSWESLGHHTIFFGRAWSKTFDEIIKR
                     GRLMSDPSLLVTRPTATDPTLAPDGREVVQVLAPCPNLRTSRIDWPRVGPRYRDELIKV
                     LEQRGLTGFGSSIEVSELITPADWEAQGLGAGTPFSLAHSFRQTGPFRPRNLVPGVDNA
                     VLAGCGTTPGVGIPPVVISGRLAAQRITGR"
     gene            complement(13838..14899)
                     /locus_tag="B9C43_RS38845"
                     /old_locus_tag="SAMN05661093_07923"
     CDS             complement(13838..14899)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099089.1"
                     /locus_tag="B9C43_RS38845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07923"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_084432203.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.8e-50, bitscore:
                     164.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIDESVRAHVERTLTEYLSAKQSTMASLTQELADALDALVEFIL
                     RGGKRIRPTFAWWGWRGAGGEPDAPAVLRAISGLELIQACALVHDDLMDASAVRRGSPT
                     VHVTFERLHRERGWLGTSERFGMAAAILLGDIALAWADDMFYGSGVSANRLAAASEPWQ
                     AMRSEMLAGQYLDILTQVEGDESPEAALRVARMKTAAYTVERPLQMGAALAGADPEVVE
                     RLRAFGADIGVAFQLRDDLLGVFGDTDVTGKPAGDDLREGKRTLLVALGLQKATQAGAD
                     VLRHCLGNQDLTGDDVERARAVLLESGAVDAVEAEIEALTSTAMHALQAADLAEPAGDR
                     LAELAVAATRRNH"
     gene            14977..15864
                     /locus_tag="B9C43_RS38850"
                     /old_locus_tag="SAMN05661093_07924"
     CDS             14977..15864
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686262.1"
                     /locus_tag="B9C43_RS38850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07924"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_033390258.1"
                     /transl_table=11
                     /translation="MTSVLERINVGRATFSVEFMPPRDDADEQILWRSIRELEGLDPAF
                     VSVTYGAGGSRRDRTIRTTGRVARETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVHNV
                     LALRGDPPGNPMGEWVKHPQGLSYAEDLVRLVCELGDFCVGVAAFPYGHPRCSDIETDA
                     DRLVQKFRAGAQFAVGQLCYSAEDFLRLRDRVAARGSDAPILPGVMPLTTPKMLSKVVE
                     LSGAPVPPQIASRLEPLVDDPKAFRSEGIDVVTEMCQQLLAEGVDVLHFYTFNRAKATK
                     EVLGRLDLVPSRTA"
     gene            complement(16048..16695)
                     /locus_tag="B9C43_RS38855"
                     /old_locus_tag="SAMN05661093_07925"
     CDS             complement(16048..16695)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF047061.1"
                     /locus_tag="B9C43_RS38855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07925"
                     /product="LppM family (lipo)protein"
                     /protein_id="WP_033390259.1"
                     /transl_table=11
                     /translation="MPLLLVLAFALSGCVRVRAAMAVDANDLISGTLEIATVQVKPEEI
                     GPALTIPAELSSQVTMEPYKAEGYVGQTVRFTQLSFDQLRTLTESISSLTSRYRLNFRR
                     SGDIVSLAGVADLTQLRPDGTDVQLKIAFPGPIGRTNGILEMDNNISWKLSPGRITDIS
                     ATSQYNAESGMSWTRWVLLVGAGAVGTALIVLALALFTHRRSRRKEQMSEYV"
     misc_feature    complement(16105..16107)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16821..18482
                     /locus_tag="B9C43_RS38860"
                     /old_locus_tag="SAMN05661093_07926"
     CDS             16821..18482
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099093.1"
                     /locus_tag="B9C43_RS38860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07926"
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_084432209.1"
                     /transl_table=11
                     /translation="MANHTAGVHGASERFVDEYATLDPITATYAGLTGYESEMTDFSPD
                     GHRQRTELASRAVREIQALEPADETEKAAKAHFLERIGLELELAEAGLDIGNINVISSP
                     AQNVRAVFDLLPAQTAEHWADIHALLAKVPAAVDGIKASLTDAANRNQLAALRQVTKVA
                     EQCETWSGGKGESFFKTFIQNAPQSSAELEGAAQRASEAYADLGRFLRQIADRAPKKDA
                     VGEDVYKLWSRYFLGAELDLREAYDWGWTEFFRVEKEMIAVAERIKAGASLSEAAAVLN
                     ADARYRIEGRAEFEQWMQRLSDNALSALRGVHFDIPDPLMRLDCKIAPDGGGAGAYYTG
                     PSDDFSRAGAMWWSLPSGRDDFSTWREVSTVYHEGVPGHHLQIATGVYQAESLNRYQRL
                     FGWVSGHGEGWALYAERLMQDLGYLTDDGDLMGMLDAHLFRAARVIIDIGMHLELEIPA
                     GSGFHDGERWTPELGLEFMLTRTLTDADVVRDEIDRYLGWPGQAPSYKLGERYWLQLRD
                     EARRRDGEAFDIKDFHMRALRLGSMGLDNLAASLRG"
     gene            complement(18441..19052)
                     /locus_tag="B9C43_RS38865"
                     /old_locus_tag="SAMN05661093_07927"
     CDS             complement(18441..19052)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015804511.1"
                     /locus_tag="B9C43_RS38865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07927"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_051897092.1"
                     /transl_table=11
                     /translation="MAETLTAEQILEAAQEVLRRFGPSKATVVDVARALGVSHGSVYRH
                     FPSKAALREAVTRQWLHRNHAPVAQAAKADLPAPDKLRNWLSTLFDTKRHKVLDDPELF
                     ATFSALVKENSTVVADHIAELTAEIAGILRDGVQAGEFAPIEDVENTARAVFDATSRFH
                     DPGYSGDWAQDGIGKAFDAVCSLVLAGLTTQAGREVVQSH"
     gene            complement(19052..20047)
                     /locus_tag="B9C43_RS38870"
                     /old_locus_tag="SAMN05661093_07928"
     CDS             complement(19052..20047)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018332095.1"
                     /locus_tag="B9C43_RS38870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07928"
                     /product="aldo/keto reductase"
                     /protein_id="WP_084432212.1"
                     /transl_table=11
                     /translation="MRNRRLGKTGPEVSELGLGAMGMSDMYGPADETESIATIHAALDA
                     GVTLIDTGDFYGMGHNEMLIGRALQDRNRDDVAISVKFGAQRSPAGQWLGYDASPNAVK
                     TALTYSLRRLRTEYIDIYRPARLDPNVPIEDTVGAIAEMVQAGYVRHIGLSEVGADTIR
                     RANAVHPIADLQIEYSLISRGIEENILPTLRELGIGVTAYGVLSRGLLSGHWSQDRANT
                     ATDFRAHSPRFQGENLAHNLTLVEALRQIADRKSVSVAQIAIAWVLSRGEDIVPLVGAR
                     RRDRLAESIGALDVDLSKEDLDVIEQTVPSDAAAGDRYAPAQMQTLDSER"
     misc_feature    complement(20062..20078)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.07"
                     /tool="antismash"
     misc_feature    20067..20085
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 21.33"
                     /tool="antismash"
     misc_feature    complement(20215..20230)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.94"
                     /tool="antismash"
     gene            20280..21032
                     /locus_tag="B9C43_RS38875"
     CDS             20280..21032
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS38875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_160097009.1"
                     /transl_table=11
                     /translation="MSKRLPVVLSLAALGLAAVALPSAAVPNRADQVRVECTADTPAVK
                     TLTAAMKAVDAAAADPAKLQSALGDVYSAVTGAQEAGCLPSLPSSTATPPAPPAPPAPP
                     APPAPPAPPAPPAPPAPPAPKAADACLAPTVDLLSAVLGGVSATLKTPPDAAATTAAVT
                     KLGTAVTAINTAKCLPVALAVPGAAAPPAPPAPPAPPAPPAPPAPPAPPAPPAPEPPAP
                     PAPPAPPAPPAPPAPPAPEPPAPPAPLP"
     gene            complement(21080..21652)
                     /locus_tag="B9C43_RS38880"
                     /old_locus_tag="SAMN05661093_07931"
     CDS             complement(21080..21652)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075039.1"
                     /locus_tag="B9C43_RS38880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07931"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_033388788.1"
                     /transl_table=11
                     /translation="MTAVPSHKSQLVELSADALRSRLYEALGLYVTAMGYPKGTAEQRA
                     PMWLAHMLREGWRCVAALDQNDELTGICYGYRGAPGQWWHEQVRRGVVELAGPGVADDW
                     MRDYFELTELHVRPDSQGRGTGERLLRMLLEGVPNDRVLLSTPEGRTRAWSLYRRVGFV
                     DVLRNYRFAGDPRPFAVLGRQLPMSSS"
     misc_feature    complement(21572..21574)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(21654..22169)
                     /locus_tag="B9C43_RS38885"
                     /old_locus_tag="SAMN05661093_07932"
     CDS             complement(21654..22169)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155372.1"
                     /locus_tag="B9C43_RS38885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07932"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_084432215.1"
                     /transl_table=11
                     /translation="MTSTDHPAVAKFTAALLEAGLTDSAAGIRILDDEVRTAAAAANAL
                     GIEVGAIANSLIFRATYGGKVEPLLVLTSGAHRADTKRVAAIVGADRIDKADPVFVKES
                     TGQAIGGVAPSGHPQRIRTLVDNHLATYAVVWAAAGHPKSVYPTTFEQLVALTGGTAAD
                     VRSVEDDS"
     misc_feature    complement(22232..22247)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.24"
                     /tool="antismash"
     misc_feature    complement(22233..22246)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.72"
                     /tool="antismash"
     gene            22367..22789
                     /locus_tag="B9C43_RS57025"
                     /old_locus_tag="SAMN05661093_07933"
     CDS             22367..22789
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156540.1"
                     /locus_tag="B9C43_RS57025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07933"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_033388786.1"
                     /transl_table=11
                     /translation="MSTTVDFPSSPSRRGSRSWASGTPSALLRQAECGIAAAEAETEPA
                     ERFAQAYLSALRAAAAMLAHRGRPHRGRARPTSAWTLLSSVAPELREWAAFFAACSSTR
                     AAVQAGRVRLVSARSADDLVRQAGQFIGLIARVVPG"
     misc_feature    22532..22534
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            22786..23565
                     /locus_tag="B9C43_RS38890"
                     /old_locus_tag="SAMN05661093_07934"
     CDS             22786..23565
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671610.1"
                     /locus_tag="B9C43_RS38890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07934"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_160097011.1"
                     /transl_table=11
                     /translation="MNGKALIDQTRLLDVLEIEATVLAETVDGAREELRIPNCPGLTVG
                     ETARHVGSGYRVALEWIRTGDSPETWQREPGPFQSLRDYVISGVRELVDELSRHEPSEP
                     CSTWWAADSTYGFWRRRMTHETVIHRVDVQAAMDLEIGEIADDIAVDGVDEILTLWLGH
                     RLTVQGVVGTRDGTVAVRTGEKAWLVRVTTGGLGAWRVPGTDIDRTDRSRIDAEITGPP
                     SNVYRYLWGRMPEIAVHREGDIDAINQMWALLRVATR"
     gene            23712..24437
                     /locus_tag="B9C43_RS38895"
                     /old_locus_tag="SAMN05661093_07935"
     CDS             23712..24437
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013224207.1"
                     /locus_tag="B9C43_RS38895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_07935"
                     /product="VOC family protein"
                     /protein_id="WP_084432218.1"
                     /transl_table=11
                     /translation="MATRLVNVIFAAANPEALADFWSRLTGWPVVAEHGEIDVRAPQSQ
                     GWELDLVFDRVDELKTTRNRVHLDLASASPADQAEIIERARDLGAKPIDVGQGNVPWEV
                     MADPEGNEFCVLEPREMYHDSGPLAAIVVQAVDADRLAKFWVEATGFERKVETGSAVGL
                     RPPNGRGPWLEFLGGYQPKTVQNRLHLDVRPAADDDQQAEVARLRAAGAKSIDIGQVDV
                     PWEVMADPEGNEVCVLTPG"
     misc_feature    23728..23742
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.08"
                     /tool="antismash"
ORIGIN
        1 acggtggagc ggagaagtat ccccagtcgt ccggaccgga gcaccagcgg aaatgagcag
       61 ccgggcgata tccggatcct gcgcgatctc aagcggcgtg ttgccgtcat cgtcggtgac
      121 cgacaacgcc gccccagtcg cgagcagcgc acggaccgca tccgcatcac cgctcgctac
      181 ggcgctatgc aggtccacgg ctgtcacgtt aggtcccggg tcgatcaacc gtccagcaaa
      241 gcccgcaacc acccagtgac atccgccatc accgcctcat cggtcatcag cgagacagat
      301 ccggcacggg cgagctgtcg ggtactcatc gagatcggac tggctgccgc agatcttcac
      361 gtaaggtccg gtccactgcg aacctcgtgt cggcgttcca ctgatcgtcc ggcatgtggc
      421 tcgatgaagg acgaggttgt tcgggttcag gcttcgctct gcgttgatga cgtagagatc
      481 agggtgcgct gcttgccacg cgaggtagcc ctcgtcgtca tcgacgaatg tctgcgccgc
      541 tgctctggcc atggggcctt ctctcagtgc gggaatgctc gccatgcccg tcgttcgatg
      601 tgctcgcggt gttgccggat gtccgtggcg acctcaaaac gtaacggcgt caatcccaag
      661 atgtgagagc agggagcggt acgcgatccg taccggttgg acgccaactt gggggaacgc
      721 atacaccgtg cacggcagtt ctgccgaggt caatcacgag gtcaggaccc gtgcgaggag
      781 taaccgtgcc cctgttcggt tgccgggtgg tcgcggcaac gcctggctgc aatcacatgt
      841 ccatgtccag caccgttaaa ttggtaaagg acaggtaggc gagtggaccc ccttgccgat
      901 gtcacgcaac gtaagtgccg aggggatgcc ggcgtagacg tcagagccgc gatgaggatc
      961 ttctcggcgt tccgcacgcg ggtgaacagc ggcggttcgg acaacgagaa cacttggtcg
     1021 aggctagctg gaggatgtgt gcaaggctcg tgctttcccg gtaacctacg tgccctaggc
     1081 cgagaggcgc tgcaacggac cgcgccggtc cgccacgctc ggtctgccac gaaggctaac
     1141 aagggcgcct cccagatgat gggaggcgat tcatgagcaa gtctctgcaa gatcttctcc
     1201 gcgagcgcgt cgtggtgctg gacggcgcct ggggcacgat gctgcagggc gcgggcctca
     1261 ctgcggccga ctaccgggcc gatttcatcg ccgacgacca ccccaaggac gtcacgggcg
     1321 accctgacct gctcaatctc acccgcccgg acgtcatcct cgacgtgcac cgccagtact
     1381 tggccgcggg cgcggacatc accaccacca acaccttcac cgccacgagc atcggccagg
     1441 gtgactacgc cctgcaggcg ctggtgcacg acatgaacgt gcggggcgcg cagctcgcgc
     1501 gccaggccgc ggacgaggcg ggtggcaagt tcgtcgcggg ttcgatcggg ccgttgaacg
     1561 tcacgctctc gttgtcgccg aaggtcgagg acccggcgta tcgcgcggtc acgttcgacg
     1621 aggtctacgc ctcctacgcc gagcagatca aggcgctcgc cgagggcggc gtcgacctgc
     1681 tgctgatcga gacgatcttc gacacgctga acgtcaaggc cgctgtcgcc gcggccaagg
     1741 acgtcgcgcc gcacctgccg ttgtggatct cggtcacgat cgtcgacctg tccggccgga
     1801 cactgtccgg gcagaccgtc gaggcgttct tcagctcgat cgagcacgcg gatcccctga
     1861 tcgtgggagt caactgttcg ctgggggctg cggagatgcg cccgcacgtc gccgatctgt
     1921 cccggctcgc gggcacgtac accgccagtc acccgaacgc gggtcttccg aacgctttcg
     1981 ggggatacga ccagacaccc gacgagaccg ccgcgttgct caaggacttc gtcgagcagg
     2041 gcatggtcaa catcgtcggc ggctgttgcg gcaccacgcc cgcgcacatc aagaaaatcg
     2101 cgcaggccgt cgaaggcctg aagccgcgtg agatcccggc gattcacccg aagacgcgat
     2161 tcagtggcct cgagccgttc gaaatcggca aggacaccgg gttcgtgatg atcggtgagc
     2221 gcaccaacgt caccggatcg gccaaattcc gccggctgat cgagggcaag gatttccagg
     2281 ccgccgtcga cgtcgcgctc gaccaggtgc gcggcggcgc gaacctgctg gacgtcaata
     2341 tggacgccga cctgctcgac agcgagcggg cgatgaccac gttcctcaac ctgatcgcga
     2401 ccgagcccga ggtcgcgcgc ctgccggtga tgatcgacag ctccaagtgg actgtgctgg
     2461 aagccggtct gaagtgcgtg cagggcaagg gcgtcgtcaa ctcgatcagc ctcaaggaag
     2521 gcgaggagca gttcctcgag cacgcccgca agatccgcag ttacggcgcg ggtgtcgtgg
     2581 tcatggcctt cgacgagaaa ggccaggccg acagcaccaa gcgcaaggtc gagatctgtg
     2641 cgcgggcgta cgacctgctc acccaaaaag ccggcttccc ggctgaggac atcatcttcg
     2701 acccgaacgt gctcgccgtc gcgacgggaa tcgctgagca caacgggtac gccaaggcgt
     2761 tcatcgacgc gttgccgttg atcaagcagc gctgtccggg cgtgcggatc agcggcggta
     2821 tctccaacct gtcgttctcc ttccgtggca acaacgttgt ccgtgaggcg atgcactcgg
     2881 cgttcctgtt ccacgccgtg aaggccgggc tggacatggg catcgtcaac gccggtcagc
     2941 tcgccgtgta ccaggacatc ccggccgact tgctggaact ggtcgaggat gtgcttttcg
     3001 accgccgcga ggacgccacc gaccggctgg tcgcgttcgc ggaaacggtg aacggcaagg
     3061 gaaccaagcg tgcggtcgac ctgtcgtggc gggaggcgcc ggtcgcgcag cgcctggaac
     3121 acgcgctggt gcacgggatt gtggacttca tcgaagagga caccgaggag gcgcgccagg
     3181 acgcggcccg cccgctcgac gtcatcgaag gtccgctgat ggacggcatg aagatcgtcg
     3241 gcgacctgtt cggctcgggc aagatgttcc tgccgcaggt ggtcaagagc gcgcgggtga
     3301 tgaagcgttc ggtggcgtac ctcgagccgt tcatggaggc cgagaaggag aagctgcgcg
     3361 ccgaaggcaa gatcgacacc aggcacggca acgggaaggt cgtgctcgcc acggtcaagg
     3421 gcgacgtgca cgacatcggc aagaacatcg tcggggtggt gctgggctgc aacaactacg
     3481 aggtgatcga cctcggcgtg atggtgcccg cggcgaccat tctggacacc gcgatcgccg
     3541 aaggcgccga cgcgatcggc ctgtccggtc tgatcacgcc gtcactcgac gaaatggtca
     3601 gtgtggcaac ggaaatgcag cgccgtggga tgaagctgcc gttgctgatc ggtggtgcga
     3661 ccacgtcccg ccagcacacc gcggtccgga tcgcgcccgc gtacgacggc tcgaccgtgc
     3721 acgtgctgga cgcgtcccgc gttgtcggtg tcgtctcgca cctgctcgac gacggcaaag
     3781 cggccgtgct ggacgaagcc aaccgggtcg agcaggctcg gttgcgtgag cagcacgaag
     3841 ccaaggagcg ccgtccactg ttgacgatcg agcaggcgcg ggcgaacccg gagcgggtct
     3901 cgttcgacga cctgccgagg cccgacttca ccggcgtgcg ctacctggag ccggacctga
     3961 acaccctgcg cgagatgatc gactggcagt tcttcttcct cgcgtgggaa ctgaaaggca
     4021 agttcccggc gatcctcgac cagccggtgg ccaaggaact gttcgacgac ggcaccgcgc
     4081 tgctggacca gatcatcgcc gacggttcgt tccacgccca gggcgcgtac gggttctggc
     4141 ccgcgcattc cgaaggcgac gacatcgtcc tcgatggaca gttgcggctg ccgatgttgc
     4201 gccagcagac cgagaagccc accggccggc cgaaccggtg tctcgccgac tacatcgcgc
     4261 cgcagggcga ccacatcggc gggttcgctg tggcgatcca cggcgccgag gacctcgcgg
     4321 cgaaatacga ggaaagcaac gacgactacc gctcgatcat ggtcaaggca ttggccgacc
     4381 ggctcgccga ggcgttcgcc gaatacatcc acctggaagc ccggcgcgcc tggttcgagc
     4441 cggacgtcga gcccaagctg gaggacctgc acgcggagcg cttccgcggc atccgccccg
     4501 cgctgggcta tccggccagt ccggaccaca gccagaagaa gcagctgttc gacctgctcg
     4561 acgccgaaaa ggtgggcatg gcgctgaccg agtcgtacgc gatgaccccg gcggcggccg
     4621 tcagcggcct gatcttcgcc aaccccgcgt cccgctactt caccgtcggc aggatcggcc
     4681 gcgaccaggt cgaggactac gcacgacgcc aggacgtggg catcgaggtg gccgagcgct
     4741 ggctgcggcc gaacctcggc tacgagacca actgaaggaa ctggtcgtag aggccggtct
     4801 tcagcttcaa gatcgcttcc tcgacccgga cggaactctg ccgggcccca gccgactcgg
     4861 caagctgcga aagccgcatg ccgagtcggc cggagtgcgt gagcgacagc ggtgaagccg
     4921 ctgccagcgg ccgggatttc gcgtcatgga cgtgatgcgg gtggtagaag accgagcgct
     4981 tgagcaacag ctcaatgaac cggggtggga ttcttgaccg gaacctagga ctgcgcgccg
     5041 agctcgaggt aggcggcgaa tgtgccgagc caatgttcgg ccgcgtagcc atagccgaac
     5101 acgtaatccc agccgacggc ggaatgcgcc tcgaacgcct ctctcgccag cgagacgtac
     5161 ctgtgcgagg agggcaacga ctcggcgatc gagcgccacg cccaggcacg ggacaggatc
     5221 agcccggaca gatgcgagcc gtgggcgccg ctcgggtcgt ccacgggcgc cggctcgcgc
     5281 aggatctgcc agcggtcggc ggtcaggtcc ggcaggaaag cgtcgaacca tttagcgaac
     5341 tcggtgccgt ccatgacccg gcgcatcagg tcggcctcgg ccagtgcggg ggagaggaag
     5401 tcggccgcgt ccggctcgaa gccgccgtat ccggcgtcgt cgaaatacca gcgcagtgcc
     5461 gcggacgtgc acgcctcagc gagttcggtg tcaccagtgg cgcgtgcggc gtccaacacg
     5521 agaccaactg cgaacgcggt gttcgcgtgg gttcccactc ggacagggaa gcgtgcgtcc
     5581 tggatccagg tgagccagtt cgcccggaga acttcattga gcggagcgac cgaccaagcg
     5641 gttccggcga gttccgcgtc caacgtcaac aaccatgccc agccgtacgg gcgctcccag
     5701 tggcgaccgg cgccggtgga gaagtacgcc gcctcagtcg tgcagccctc gggagtgatc
     5761 aacgaggtga gcacggattt cgccgaggcg gccccgggta agtccgggtc gtggcgcagc
     5821 agccgggccg ccagccaggt ctggtgcacg cacgaatgcc agtcgtacga ccctgcgaac
     5881 accgggtgca gtgtgcggtg cggcaccagg tcctcgggac cggcgatcag cctggtccag
     5941 tgcactggat agtcacgctg gacgttggcg acggcggtgt cgagcaaccg gttcgcggtc
     6001 tgcctgtcca accgggtcgt gcggggaagt ggggacatga cccccaatcc tgcctgacga
     6061 taaaaccgtc ttgccgacct cttaggctag aggggtgaac tggaccgtgg acgtgcccgt
     6121 ggacacgctt cccgaactgc ccccactgcc gccgcacctg cgcaaggcgc tcgacgaagc
     6181 cctggccaag ccggccgcgc agcagccgga gtggccggac caggacaacg tgcgcaaggt
     6241 ccgcacgctg ctggagtccg tgccgccgat caccgtgccc gccgagatcg accggctgca
     6301 ccagcggctc gccgaggtcg ccaacggcga ggcgtttctg ctgcagggcg gtgactgcgc
     6361 cgagaccttc gcggacaaca ccgagccgca catccgcggc aacatccgca cgttgctgca
     6421 gatggccgtg gtgctcacct atggcgcgag cctgccggtg gtgaaggtcg gccggatcgc
     6481 cggtcagtac gccaagccac ggtccaaccc caccgacgcc ctcggcctgc cggtctaccg
     6541 gggtgacatc gtcaactccc tggtcgccac gcccgaggcg cgggtgccgg acccgtcccg
     6601 catgatccgc gcgtacgcca acgcgggcgc cgcgatgaac ctgctgcgtg ccctgaccgg
     6661 cgcgggcatg gccggccttg cgatggtgca cgactggaac aaggacttcg tgcgtacgtc
     6721 cccggcgggt gagcgctacg aggcgctggc cgccgagatc gaccgtggcc tgcgattcat
     6781 gcaggcctgt ggcgtgcacg actactcgct cgagcacacc gagatcttcg ccagccacga
     6841 ggcgctgttg ctcgactacg agcgcgccct gctgcggatg gacgtctgcg gcgaggagcc
     6901 gaagctgtac gacctgtcct cgcacttcct gtggatcggc gagcgcacca ggcagctcga
     6961 cggcgcgcac atcgcgttcg ccgaactgct gtccaacccg attggcctga agatcggccc
     7021 gaccaccagc cccgagctgg cggtggagta cgtcgagcgc ctagacccgc acaacaagcc
     7081 gggtcgtctg acgctgatca gccggatggg caaccacaag gtgcgcgacg tgctgccggg
     7141 catcgtggag aaggtcgaag cgtccggcca caaggtcatc tggcagtgcg acccgatgca
     7201 cggcaacacc catgagtcct cgaccggcta caagacccgg cacttcgacc ggattgtcga
     7261 cgaggtccag ggcttcttcg aggtgcaccg caggctcggc acgcaccccg gcggcatcca
     7321 cgtcgagctg accggcgagg acgtcaccga gtgcctcggc ggcgcgcagg agatctccga
     7381 cacggacctg tccggccgct acgagaccgc gtgcgacccg cgcttgaaca cgcagcagtc
     7441 gctggagctg gcgttcctgg tcgcggagat gctccgctcc tgaacacgtc catgagaatg
     7501 cccccggcgc gccgcgtcgg gggcaatttc atacgccaaa gttttccggc agccgtcgtc
     7561 gcaaccgccc agggggaccc ccgaatttca cgttacccca ggggtccgac agttttagct
     7621 gccgaagaag ttcaccgcca cccggaccgt cgagcccttc tgcacccggc tgcccgggtt
     7681 cgggccctgg gcgaagatcc gccggttgcc gcggtcgtca ccgaacgcca gctccagctt
     7741 caagccgagt ttgtccagct gttccttggc gtcgttgatg cgtttgccgt tcaggtccgg
     7801 cacggtcacc gcgttcgaca cggtcagcgt gacctttttc tcctcggaca cggttccggc
     7861 cacggggtcg gtcgagatca cccggccgcc gtcgacccgt tcgtcgaacc gggtgttcac
     7921 cgtgacggtg tatccggctt cctggacgag ctggcgcgcc tcggcttcgg tcttgccgcg
     7981 tacgtccggc agtggcttga gcggggccgg gcccttgctg aggaccatta tcacttcgtc
     8041 gccgagcttg agctgtgtgc ccgggctggg ggacagggcg accacgctgc ccttcggcgc
     8101 gttgttgtcg aacctgtcct cttccgtgga cagtttcggc ttgaggtcct gggcccgtaa
     8161 tgcgttctcg acgtccggca cggtcgcacc gggttcgacg tccggcacga tcggcgggcc
     8221 gaccgagacg tacacgttca cgccggatcc cgggatgagc gtgccggtcg gcgggtcggt
     8281 cctgatcacc ttgttgcggg cgaccgagtc gctgcgggac tccaccacgg tgggcaccag
     8341 tttggcgtcc tcgatccgtt tcagcgcgga ctgcttgtcc gcgccgacca cgttcgggat
     8401 ggcgaccggc tcaggcccgg cggtcaggaa gatcgtcgcg acgatcgccg cgacggccag
     8461 cacagcggcc gcgatgcccc aacgcgggat cgggaaacgt ttgcggggtg gttccttctt
     8521 cttctcgacc ggggaccggg gcggcttgga cggtgggtcc aagtcgctgc gcaccatggc
     8581 ccgcgttccc tgcggaccgg ggacagttgg cgctgcgggc ggcacaggct cggtctggac
     8641 cgtgggcata tccgtggcga cgcgaggcac ggtctgcatg ccgtgcgctg cagctgggat
     8701 cggcacgagt ggagcgccaa tggcgtgtcg cacacgctcg acttcctgca gaaacgctcc
     8761 ggcgtcagct ggccgtgcca tcgggtcacg gcgcgtcgcg cgcagcacca gctcgtccag
     8821 tgcctggggg atcccgggtg ccgacaggct tggcggcggg acgtcgtcgt tcacgtgccg
     8881 gtacgccacc gaaatcgggg tgtcgccgac gtacggcggc tggccggtga gcatctcgta
     8941 caacagcagg cctgccgagt acacgtcgcc gcgggccgtt gtcacgcccg tcgccacctg
     9001 ttccggcgaa aggtaggcga ccgtgccgag gatgacgctg ttgctcgtgt tgttcccgct
     9061 ggccatcgcc ttgaccaggc cgaagtcgcc gaccttgacc acgccggact tgccgatcag
     9121 cacgttctcc ggcttgacgt cccggtgcac caggccgttc tggtgcgccg cggccaacgc
     9181 cgacagcacc ggctcgagca ccgacagcgc cagcgggacg gtcagccggc cgcgttcgac
     9241 cagcaggtca cgcaaggtgc cgccgtccac cagctccatc accaggaaca cgtggtcccc
     9301 gtcgaagccc tggtcatgca ctgcgatgac gttcgggtgg tgcaggctcg ccgcggctct
     9361 cgcctcacgc tcgaaccggt cgacgaacga ctggtcctcg gcgaaccggt gatccatcac
     9421 cttgatcgcg accggccgct cgaggcgcat gtccatgcca cggtagacag ccgacatacc
     9481 gccgcgggcc agcggcgcgt cgacccggta acgctgctca agcaacgtcg ccattccaag
     9541 cccgcctctt tcctgcacgt gtgcgatcgt acggatcggt ttgctccttg tgggtcggcc
     9601 tgcctcattt ctcatacgtg tggcgtgtgg catcgtgttc atccgtgagt gcgattccca
     9661 ttgctgacga tgtgctcgac ccagcggtgg aggtgttgac cctgcgggag gtggccgatc
     9721 gcgtcggccg tccggtcagc cgtgtccagc aggcccttcg ggaccaccag ctgatcgcgg
     9781 tgcgcaggcg tggcgagctg ctcgttccgg cgatcttcct gaccgacaac gacgaagtgg
     9841 tcaagggcct gccagggacg atcaccctgc ttgtcgactc tggctactcg ccgagcgaga
     9901 tcctgcggtg gctgttcacg gccgacgagt cgttgccggg cacgccgatc gaggcgctgc
     9961 gtggtgaccg gggccgtgag gtcaagcgca gggcccaagc cctggcgttc tgaccagcgg
    10021 ctttcgtcgc agccggcagg gcgactcgca gtcgctggcc ggtgggcacg accgcgcgcc
    10081 ggttcaggat ctcgtagtcc acggcgacga tctcgtcgag gatgccgcgg tagagcttcg
    10141 ccgcggtgct gacacacggc cttgaccagg gccgaagcag ctcgatgcct ggctcggcgc
    10201 ggcggtagat cgccaccgtg cgcgcgacca tatgggctaa cgccctgcgt atgtacgggt
    10261 catgccgccc tgtccttctg gcccaacgca accggtcgcg gtcgacaccg aacgcggcca
    10321 gctcgtccat cggcaggtac acgcggccac ggtcgaggtc ttcgccgacg tcccgcagga
    10381 agttggtgag ctggaacgcc tcgccgagcg cggcggcgta cggttcggcc tcctcctgcg
    10441 gcgacactgt gccgaggacg ggaagcatct gcaggccgat cacgctggcc gagccgtaga
    10501 cgtactcggc caggtcggca taggtctcgt accgcttgac gtgcaggtcc atccgcatgg
    10561 acgcgaggaa gtcggagaac agccgccggt cgatccggta gcgccggacg gtgtcggcca
    10621 gcgcgcgcaa cacgggttgc ccgccgtccc acatggtccg ctcgagcgcc agcaactcca
    10681 tggtctgctg ggacttcggc agcgagccgt ccacgatgtc gtccgcgacg cgcgcgaagc
    10741 cgtacagcgc gtgcaccgcc gggcgatctg cgatcggcag caaccgggtc gccaggaagt
    10801 aagtccggcc gtgactggcg ttgatggcct tgctttcggc gtacgcggcg cgcagttcag
    10861 gatccgtgat cccggcagcg tccagttcac gcgtactcac gaacaccctc ccccgacaaa
    10921 caccgcggcg ccagcctagg tcatttcggc gagcacccga cccactgggc aggcgggcat
    10981 tgccccacac ggccacggta tgcgtcgacg agttgccggg ccaaagcgtg tgcggaagcc
    11041 gggtcgcccg tggccgcgac ctcgtcgacg acacagccag cggtgcagaa tttcagctgc
    11101 tcatcgggga ttttgcgcca gtcagggcca gtggcgacgc cgtacttcca gatctgcttg
    11161 tcgtctttgc ccgcgtcgtc gcggatcacg tagacgtgct ggttgccctg cggattggcc
    11221 actggagtct ccgcagagct cgccaacgtg cgcaggccgg ttggatcagg cggcgtgata
    11281 agcgccatag ccgtccattc ggcgccatac ggatgctgcc cgggcacgga ctgcgcgcgg
    11341 cggtagaact gcgtccactg cggcgaggac agcgtgcacg tcgcgctgcc tgcctggctg
    11401 ggctgcaagg ggccgactcg gctctcgcac gaaccgatca cgttgccgcc accggtccac
    11461 gtcgccttga ctgccacccg tacggcctgt ttgcccacgt tggtgagctc gaccacgatg
    11521 gcgcagctgc tcacgccgca gttctggaac ttgtgcgtgc cctgcttgac cccggtgaac
    11581 gggtcgtacg cggtctccag ttcggcggtc ttggccgcga ggtcacggta gagcgcggcc
    11641 atgtcactgg tggcgtccga aacgctgaac gccaggtcac gcaccttggt cggatccgtc
    11701 ttgcccgact tggtcagatc gaaccggacc agtccgtacg gcgggttcac gcccaggtag
    11761 agcacgcccg cgtcggtcgg cacctccagg acgtcctgac cggcgacttt ggtgcgtttg
    11821 acggcgtccg gcgtctggtt ggcgaggggt ttgccgaaca ggcccgggag cgtctcggtg
    11881 tcgaagatcc gctcgatgtc gacgccgagc agcacgccgg gcgctttgac ccagtggtcg
    11941 gcgaccgtcg gcgcggtcga gtcggggaca ccggacagct tcagccagaa atccagcccg
    12001 gccttgaggt acagcgtgtg gtcgacgacc agcacggtcg cgggcagccc gttcaccgac
    12061 agctcgccgg tcgcctcacc ggccttggtc acggtcacct gcatcgtgac gttgtcgccg
    12121 gccggcgcgg tcagcgaacc gttgtaccgc acggcaccgg cactcctgag gtccacaatg
    12181 gactgagcga ccgcgtcggc cgcgaccagc ttgggcgcgg gagcggggcc gttgggtgac
    12241 ggctcgtcgc cggtgcatcc ggcgcatagc aggaccgtca ccaacagggt gccgagtccg
    12301 cgccgtatca cgcgttcaac gttagttgac tactggccga agtcgactcg acggcacggt
    12361 ccggcacata ttcgctacct tccggtgatt ctctgcgcgg cgagccgccc ggagatcacc
    12421 accggtggaa tcccgacgcc aggagtcgtg ccacagcccg caagcacggc gttgtccacg
    12481 ccaggcacca ggttgcgtgg ccggaacgga ccggtctggc ggaacgagtg cgccagcgag
    12541 aacggcgtac ccgcgcccag gccctgagct tcccagtcag ccggggtgat cagctcggac
    12601 acctcgatcg acgagccgaa gccggtcagc ccgcgctgtt ccagcacctt gatcagctcg
    12661 tcgcggtacc gaggaccgac acgcggccag tcgatgcggg aagtccgaag attcgggcac
    12721 ggcgccagca cctgaaccac ctcacggccg tccggcgcga gggtcggatc ggtcgcggtc
    12781 ggccgcgtga ccagcagtga cggatcgctc atcagccgcc cacgcttgat gatctcgtcg
    12841 aacgtcttgg accaggcgcg accgaagaag atcgtgtgat gcccgagcga ctcccacgac
    12901 cggttcacgc cagcgtgcag caccacggcg gagggcgacc actgcaacgg caccaggcgg
    12961 cgtgacggca accccagcag gccacgggca atcggcaagt ccggcgtcag aaccacggcg
    13021 tcgcaggaga tccgctcacc ggcagtcgta cgcacggccg tcacgcgaga accgacgcgt
    13081 tccaaccacg ccgcgccaca cgaataacgc acgtccgcgc ccgcgtcgga cgccgccttc
    13141 gccatgtgct cggcgaccgc agccacacca ccgcgcggaa accacacgcc cgcaatggtg
    13201 tccatgtacg cgatcacgcc gtacgccgcc aatgcccgct gcggcggcac acccgcgtac
    13261 agcgactgga acgagaaaag ccgctgcaac cgctcgtccg acaggtactt cgagatcgct
    13321 ggtccgagcc gcccgaaccc acccagcgcg accaggctcg ccagctgaga acccagcagg
    13381 tccagcggcg agtcgaagtt cgcgccgatg aacgaatccc gctcgacccg gtacagctcg
    13441 gtcagccatt tccgcagcct gcggtacccg acggcctcgg cgggcccggc cacgccgcgg
    13501 atctcgtcct ccatcgccgc ggcatcggag tgcacgtgga tcgtgctgcc gtcggcgaaa
    13561 tgcgcgcggt acgccggatc cagcttgatc aagtccacca tcggggcccc gacctgggcc
    13621 aacgcgtcct cgatcaaccc gggcatggtg agcacgctcg cgcctgagtc caccgtgtac
    13681 tcgccgatcc gcatccggcc cgcgcgcccg ccaggcgtgg agccggtttc cagcaccgtg
    13741 acctgatgcc cggacccgag caggtgcaac gcgcacgaca accccgcgag accggcgcca
    13801 accacgatga catggtcggt ccggccggtg accgttctca gtggttcctc ctggtcgcgg
    13861 ccaccgcgag ctcggcaagc cggtcaccgg caggctcggc gaggtcagcc gcctgcagcg
    13921 cgtgcatcgc agtggacgtg agcgcctcga tctccgcctc gaccgcgtcc acagcaccgg
    13981 actcgagcag caccgcgcga gcccgctcaa cgtcgtcgcc ggtcaggtcc tggttgccga
    14041 ggcagtgccg cagcacgtcc gcgcctgcct gcgtggcttt ctgcaggccg agcgccacga
    14101 gcagggtccg cttgccctca cgcaggtcgt cgcccgcggg cttgccggtc acgtcggtgt
    14161 cgccgaacac gccgagcagg tcgtcacgaa gctggaaagc cacgccgatg tccgcgccga
    14221 acgcccgcag ccgctccacc acctcgggat ccgcgcccgc cagggcagcg cccatctgca
    14281 gtggccgctc cactgtgtac gcggcggtct tcatccgggc cacccgcagc gccgcctcgg
    14341 gcgattcgtc gccctccacc tgcgtgagga tgtccaagta ctggcccgcg agcatctccg
    14401 agcgcatcgc ctgccacggc tcactggccg cagccagacg attcgccgag acaccagagc
    14461 cgtagaacat gtcgtccgcc cacgccagcg cgatgtcgcc gagcaggatc gcggccgcca
    14521 tgccgaaccg ctccgaggtc cccagccaac cccgctcgcg gtgcagccgc tcgaacgtca
    14581 catgcacggt cggcgaaccc cggcggaccg cggaagcgtc catcaggtcg tcgtgcacga
    14641 gcgcacacgc ctggatcagt tccaggccgc tgatcgcacg cagcacagcc ggagcgtccg
    14701 gctcgccgcc cgcgccacgc cagccccacc acgcgaacgt cggacggatg cgtttgccgc
    14761 cccgcaggat gaattcgacc agcgcgtcga gtgcgtccgc cagctcctgg gtgaggctgg
    14821 ccatagtgga ctgcttggcc gacaggtact cggtcaaggt ccgctcgacg tgggctcgga
    14881 cggactcgtc gatggtcatc ggatgcacac ctccatcgtg accccctgct cagttggccg
    14941 acgcggcggg gtcggaagtc ccgataggct tgaggtatga cgtccgtgct ggagcgcatc
    15001 aatgtcggca gagcaacgtt ctccgtcgag ttcatgccgc cccgagacga cgccgacgag
    15061 cagatcctct ggcgatcgat ccgtgaactc gaaggcctgg acccggcctt cgtgtcggtg
    15121 acctacggcg cgggcggatc ccggcgtgac cgcacgatcc gtacgaccgg ccgtgtagcc
    15181 agagagacga cgctggtgcc gatggcgcac ctgacggccg tcgaccactc cgtcgccgag
    15241 ctgcgcaacg tcattggctg gtacgcggct gttggcgtgc acaacgtcct cgcgctgcgt
    15301 ggcgacccgc ccggcaaccc gatgggggag tgggtcaagc acccgcaagg cctcagctac
    15361 gcggaagacc ttgtccggct ggtctgtgag ctcggcgact tctgcgtcgg cgtggccgcg
    15421 ttcccgtacg gacatccccg ctgctcagac attgagaccg acgcggaccg gctcgtgcag
    15481 aagttccgcg cgggcgccca gttcgcggtc ggccagctct gctactcggc cgaggacttc
    15541 ctcaggctgc gtgaccgggt cgcggcccgg ggcagtgacg ccccgatcct gcccggtgtg
    15601 atgcctctca cgacgccgaa gatgctcagc aaggtcgtcg aactgtccgg cgcgcccgtg
    15661 ccaccgcaga tcgcgtcccg gctcgagccg ttggtggacg acccgaaggc gttccgctcc
    15721 gaaggcatcg acgtggtcac cgagatgtgc cagcagctgc tggccgaagg tgtggacgtg
    15781 ctgcacttct acacgttcaa ccgggcgaag gcgaccaaag aggtgctcgg caggctcgac
    15841 ctggtgccca gccgcacggc gtgagtcagc agcacaaggc cttcagccct gctgtggaca
    15901 actagctcga gccaacggtc cgttcgcgaa tccggttgtc cacagggttc tcgacgctga
    15961 ccgaacccag ccggacccac tggattccgc gccttctgtc acgcggagga tcccggaacc
    16021 cctgcgcggg acgggtggcc ggcctggcta gacgtactcc gacatctgct ctttgcggcg
    16081 gctgcggcgg tgcgtgaaca gggctaaagc cagcacgatc agcgcagtcc cgaccgcgcc
    16141 cgcgccgacc aacagcaccc atcgcgtcca cgacatcccg gattccgcgt tgtactggga
    16201 agtcgcgctg atgtcggtga tccggccggg gctgagcttc cacgagatgt tgttgtccat
    16261 ctccaggatg ccgttggtgc ggccgatcgg accagggaac gcgatcttga gctggacgtc
    16321 ggtcccgtcc ggccgcagct gggtcagatc agccaccccg gcgagcgaga cgatgtcgcc
    16381 cgaccggcgg aagttcagcc ggtaccggct ggtcaacgag ctgatcgact cggtgagtgt
    16441 gcgcagctgg tcgaagctga gctgggtgaa ccggactgtc tggcccacgt agccctcggc
    16501 cttgtacggc tccatcgtga cctggctgga cagctcggcc ggaatggtca gcgccgggcc
    16561 gatctcctcg ggtttgacct ggacagtggc gatctccaaa gtgccggaga tcaagtcgtt
    16621 ggcgtcgacc gccatcgccg cgcgcacccg cacgcagccg ctgagcgcga acgccagcac
    16681 aagcaggagt ggcacaacag cccaccggcg ggctgaacgg tggggagcct ggtgcacgcc
    16741 ggtcactatg ccaggggtgt ccagtccttt gcgaaatccg gcgggttcat cgcataacca
    16801 caccgggtaa cgtcccggat atggccaatc acactgcggg ggtccacgga gcgagtgagc
    16861 ggttcgtgga cgagtacgcc acccttgacc cgatcaccgc cacatatgcc ggactgaccg
    16921 gctatgagtc ggagatgacc gatttctccc ctgacggtca ccggcagcgc accgaactgg
    16981 cttcccgtgc cgttcgcgag atccaggcgc tagaacccgc tgacgagacc gagaaagcgg
    17041 caaaggcgca tttcctggaa cgcatcgggc tcgaactcga gctggccgag gccggtctgg
    17101 atatcggcaa catcaacgtg atctccagcc cggcgcagaa cgtccgggcg gtcttcgacc
    17161 tgttgcccgc gcagaccgcg gagcactggg cggacatcca cgccttgctg gccaaggtgc
    17221 ccgcggccgt cgacgggatc aaggcgagcc tgaccgacgc ggcgaaccgc aaccagctgg
    17281 ccgccctgcg ccaggtgacg aaagtcgccg agcagtgtga gacctggtct ggcggcaagg
    17341 gagagtcgtt cttcaagacg ttcatccaga acgcgccgca gtcgtcggcc gaactcgagg
    17401 gcgcggcaca gcgggcttcc gaagcgtatg cggacctcgg gcgcttcctg cggcaaatcg
    17461 ccgaccgggc gccgaagaag gacgccgtcg gcgaagacgt ctacaagctg tggtcgcggt
    17521 acttcctcgg tgcggaactt gatctgcgcg aggcgtacga ctggggctgg accgagttct
    17581 tccgcgtgga aaaggaaatg atcgcggtcg ccgagcggat caaggcgggc gcatcgcttt
    17641 ccgaagccgc cgcggtgctc aacgctgatg cgcgttaccg gatcgaaggg cgcgccgaat
    17701 tcgaacagtg gatgcaacgg ctgtccgaca acgcgttgag cgcgttgcgg ggggtgcatt
    17761 tcgacatccc ggatccgttg atgcgactgg actgcaagat cgcaccggac ggcggtggcg
    17821 cgggcgcgta ctacaccggg ccgagcgacg atttctcccg cgcgggcgcg atgtggtggt
    17881 cgctgccgag cggccgcgac gacttcagca cgtggcgcga agtgtccact gtgtaccacg
    17941 agggtgtgcc ggggcatcac ctgcagatcg cgaccggcgt gtaccaggcc gagtcgctca
    18001 accgctacca gcggctcttc ggctgggttt ccgggcacgg cgagggctgg gcgctgtacg
    18061 ccgagcggct catgcaggac ctcggctacc tcaccgacga cggtgacctg atgggcatgc
    18121 tggacgcgca cctgttccgg gcggcgcggg tgatcatcga catcggcatg caccttgagc
    18181 tggaaatccc ggcaggcagc gggttccacg acggcgagcg gtggactccg gagctgggtc
    18241 ttgagttcat gctgacccgc acgctcaccg acgccgatgt cgtacgtgac gagatcgacc
    18301 ggtacctcgg ctggccaggg caggcgccgt cgtacaagct cggcgaacgc tactggctgc
    18361 agctgcgtga cgaggcgcgt cgccgcgacg gggaagcctt tgacatcaag gatttccaca
    18421 tgcgtgcgct gcgcctcggc tcaatgggac tggacaacct cgcggccagc ctgcgtggtt
    18481 agcccggcga ggacaaggga gcagacggca tcgaacgcct tgccgatgcc gtcctgcgcc
    18541 cagtcacccg agtagccagg atcgtggaac cggcttgtgg cgtcgaaaac ggcacgagcg
    18601 gtgttctcga cgtcctcgat cggcgcgaac tcgcccgctt ggacgccgtc ccgcaggatc
    18661 ccggcgatct cggcggtcag ttcggcgatg tggtcggcga ccactgtgct gttctccttc
    18721 accagtgcgg agaacgtcgc gaacagctca gggtcgtcca acaccttgtg ccgcttggtg
    18781 tcgaacagcg tcgacaacca gttgcgcagc ttgtcgggag cgggcagatc ggccttggcc
    18841 gcttgggcga ccggcgcgtg gttgcggtgc agccattggc gtgtcacggc ttccctgagc
    18901 gcggccttgc tcgggaagtg ccggtagacg ctgccgtggc tgacgccgag tgcgcgggcg
    18961 acgtccacga cggtcgcctt gctcgggccg aagcggcgca ggacttcctg cgccgcttcg
    19021 aggatctgtt ccgcggtgag cgtttcggcc atcagcgttc gctgtccagc gtctgcatct
    19081 gagcgggtgc gtaccggtca cccgcggccg cgtcggacgg cacggtctgc tcgatcacgt
    19141 cgagatcttc cttcgacagg tcgacgtcca gcgcaccgat cgactcggcg agccggtccc
    19201 gcctgcgggc accgaccaac ggcacgatgt cttcaccccg tgacagtacc caggcgatcg
    19261 cgatctgagc gacagacacc gacttgcggt cagcgatctg gcgcaacgcc tcgaccagcg
    19321 tcaggttgtg cgcgaggttc tcgccttgga accgcgggct gtgcgcacgg aagtcggtcg
    19381 cggtgttcgc cctgtcctgc gaccagtgcc cggacagcag gccgcgggaa agcacgccgt
    19441 aagcggtcac gccgatgccg agttcccgca gcgtcggcag gatgttctcc tcgataccgc
    19501 ggctgatcag cgagtattcg atctgcaggt cggcgatcgg gtgcaccgcg ttcgcccggc
    19561 ggatggtgtc cgcgccgacc tcggacaggc cgatgtggcg gacgtagcct gcctggacca
    19621 tttcggcgat cgcgccgacc gtgtcctcga tcgggacgtt cgggtccagc ctggcgggcc
    19681 ggtagatgtc gatgtactcg gtgcgcaggc gacgcaggga gtaggtcagc gccgtcttca
    19741 ccgcgttcgg gctggcgtcg tagccgagcc actgaccggc gggagagcgc tgcgcgccga
    19801 acttcacgct gatcgccacg tcgtcgcggt tgcggtcctg caaggcgcgg ccgatgagca
    19861 tctcgttgtg gcccatgccg tagaagtcgc cggtgtcgat cagggtgacg ccggcgtcga
    19921 gcgcggcgtg gatcgtggcg atgctctcgg tctcgtcggc cggaccgtac atatcggaca
    19981 ttcccatcgc gccgagtccc agctcggaca cctcggggcc ggtcttgcca agtcgacggt
    20041 ttcgcacggg attcctccta gctgtgatgg tggatcaagt atgcacattg cgatgacaga
    20101 tttcaatatt tgtcagttga ctggttgcga acggtatcta accacttccc gtgcgtaacg
    20161 ccactcgggc caccctaacc ggtgaaatac gacgttttag caggtcaaag gtggtgtgac
    20221 ggtgcttacc atcggcctcg cccggatctt cgccggggaa aaaccacaag gagaatccga
    20281 tgtccaaacg attgcccgta gtgctgtcgt tggcagcact gggcctggcc gcggtggcgc
    20341 tcccgagcgc cgcggtcccg aaccgggccg accaggtccg ggtcgaatgc acggccgaca
    20401 cgccagcggt caagacattg accgccgcca tgaaggcagt ggacgcggct gccgccgacc
    20461 cggccaagct gcagagtgcg ctgggtgacg tctacagcgc ggtcacgggt gcgcaggaag
    20521 ctggttgtct gccgtcgttg ccctcgtcga cggcgacacc accggctccg cccgcacccc
    20581 cggcacctcc cgcgccacct gcgcctccgg ctccgcccgc gcctcccgcg ccaccggctc
    20641 cgcccgcgcc caaggctgcg gacgcgtgcc tcgctccgac ggtcgacttg ctgagtgcag
    20701 tgctgggcgg ggtcagcgcc acactcaaga cgccaccgga cgccgccgct acgaccgccg
    20761 cggtcaccaa gctgggcacg gccgtcaccg cgatcaacac tgccaagtgc ctgcctgtcg
    20821 cactggctgt tcctggtgcg gcagcgccac ctgcgcctcc ggctccaccg gctccgcccg
    20881 caccaccggc gcctccggca cctccggctc cgcccgcgcc accggctccg gaaccgcctg
    20941 ccccgccggc gccaccggca ccgcctgccc cgccggcgcc accggcaccg cctgccccgg
    21001 agccgccggc tccgccagcg ccattgcctt aagtgagcgg cagaatcccc tcgtgagtgg
    21061 ctggtctagg accggccact cacgaggatg acatcggcag ctgacgtccc agtacggcga
    21121 acggccgtgg atcaccggcg aaccggtagt tgcgcagcac gtcgacgaac ccgacgcggc
    21181 ggtacaggct ccaagccctg gtgcggcctt cgggggtgga cagcagcacc cggtcgttgg
    21241 gaacgccctc cagcagcatt cgcagcaggc gctcgccggt gcccctgcct tggctgtccg
    21301 gccgcacgtg cagctcggtc agctcgaagt agtcacgcat ccagtcgtcc gcgacgccgg
    21361 ggcccgccag ttcgaccacc ccgcgccgga cttgttcatg ccaccactgg ccgggtgctc
    21421 cccggtagcc gtaacagatc ccggtcagct cgtcgttctg gtccaacgcc gcgacgcagc
    21481 gccacccctc tcgcagcatg tgcgccaacc acatcggcgc cctttgctcg gcggttccct
    21541 tggggtagcc catggccgtg acgtacaggc ctaatgcctc gtagagccgc gaccgcaacg
    21601 cgtcggccga cagctcgacg agctggctct tgtgcgatgg caccgcggtc acgtcaggaa
    21661 tcatcctcca cgcttcgaac gtccgcagcc gtccccccgg tgagggcgac cagctgttcg
    21721 aacgtagtgg ggtacacgga tttagggtgc ccagcggccg cccagaccac cgcgtacgtg
    21781 gccaaatggt tgtccaccag tgtgcggatt cgttgcgggt ggccagaagg cgcgaccccg
    21841 ccgatggcct gaccggtgct ctccttgacg aataccgggt ctgccttgtc gatccggtcc
    21901 gcgccgacga tggccgcgac ccgcttcgtg tccgcgcggt gcgcaccgga tgtgagcacg
    21961 agcagcggct cgaccttgcc cccgtacgtc gcgcggaaga tgaggctgtt ggcgatcgcg
    22021 ccgacctcga tgcccagcgc gttcgcggcg gccgccgcgg tgcgcacctc gtcgtcaagg
    22081 atccggatgc cggccgccga gtcggtcagc ccggcctcta gcagggccgc ggtgaacttg
    22141 gcgacggctg gatggtcggt ggatgtcacc cgctaatcac accatgacct cggtttgagc
    22201 agcttgagcg gttggcggca cccaggtaga ctcgaacacg tgttcgaaat cgaacacggc
    22261 tgcccggtgg tggggcgggg gaagcgcctc gccaccgggt ccaccggctt ccccacggtg
    22321 ggttcgatgc ggccgccctg gccgtttcga ggcgtgagga ggccagatgt caaccacagt
    22381 cgacttccca agctccccct cgcgtcgagg cagtcgctca tgggcatcgg gaacaccgtc
    22441 cgcgctgctt cgccaggccg aatgtggcat cgcggcagcg gaggcggaga ccgaacccgc
    22501 cgagcggttc gctcaggcgt atctgtccgc gttacgagcg gccgccgcga tgctcgcgca
    22561 ccgcggccgt ccgcaccggg gccgcgcccg ccccaccagt gcgtggacgt tgttgtcgtc
    22621 cgtcgcgccc gaactgcgcg agtgggccgc cttcttcgcg gcgtgctcgt ccaccagggc
    22681 cgcggtacag gccggccgtg tccggctggt cagtgcccgc tcggcggacg acctggtcag
    22741 gcaggcaggt cagttcatcg gtttgatcgc ccgggttgtc ccggggtgaa cggaaaggcg
    22801 ctgatcgatc agacaaggct gctggacgtc ctggagatcg aggccacggt gctggccgag
    22861 acggtggacg gggcgagaga ggagctgagg atcccgaact gtccgggcct gaccgtcggg
    22921 gaaacggcca ggcacgtggg cagcgggtac cgggtggcgc tggagtggat caggaccggg
    22981 gactccccgg agacctggca gcgtgagccg ggtccgttcc aatcgttgcg ggactacgtg
    23041 atcagcggag tacgtgaact ggtcgacgaa ctgtcccggc acgaaccgtc ggagccgtgc
    23101 tccacctggt gggcagcgga ttcgacgtac ggcttctggc ggcgccggat gacgcatgaa
    23161 accgtgatcc accgggtgga cgtgcaggcg gcgatggacc tggaaatcgg cgagatcgcc
    23221 gacgacatcg ctgtcgacgg cgtcgacgag atcctcaccc tctggctcgg ccatcgcctg
    23281 acagtccagg gagtcgtcgg cacaagggac ggcacagtcg ccgtccggac cggcgagaaa
    23341 gcgtggctgg tccgcgtgac gacgggcggc ctcggcgcat ggcgcgtccc gggcacggac
    23401 atcgacagaa ccgaccggag ccgcatcgac gccgagatca ccggcccacc gtcgaacgtc
    23461 taccgctatc tctgggggcg aatgccagag atagcggtgc acagggaagg agacatcgac
    23521 gcgatcaacc agatgtgggc cctgctgcgg gtagcaaccc gctgagacga cggtcgccac
    23581 cccgcgcggc gaccatccgg agcgggaggg cgctgcgctg accagtccgc agccagcgcc
    23641 ctgccgcgca gactttcctt gtcccgcaac atcaacctga aaatgtcggt agcggctgct
    23701 agcttgcgcc catggctacc agactggtga acgtcatctt cgccgccgcg aacccggaag
    23761 cgctcgctga cttctggtcg cggctgacgg ggtggcctgt cgtggccgaa cacggcgaga
    23821 tcgacgtccg agcgccgcag tcccaaggct gggaactgga tctcgtattc gatcgcgtcg
    23881 acgagctcaa gaccacccgc aaccgggtgc atctcgacct ggccagcgcc agccccgctg
    23941 atcaggccga gatcatcgag cgggccaggg acctcggcgc gaagccgatc gacgtcgggc
    24001 agggcaacgt tccgtgggaa gtcatggcgg accccgaggg caacgagttc tgtgtcctcg
    24061 agccgcgtga gatgtaccac gactcgggcc cgctcgcggc gatcgtcgtc caggcggtgg
    24121 acgccgaccg tctggcgaag ttctgggtcg aggcgaccgg tttcgaacgc aaggtcgaga
    24181 ccggcagtgc tgtggggctg cgtccgccca acggccgagg gccctggttg gagtttcttg
    24241 gcggttacca gccgaagacc gtccaaaacc ggctccacct tgatgtccgg ccagccgccg
    24301 atgacgacca gcaggccgaa gtggcaaggc tgcgcgcggc gggtgccaag tcgatcgaca
    24361 ttggccaggt agacgtgccg tgggaggtga tggctgatcc agagggcaat gaggtctgtg
    24421 tcctgacgcc gggttagacc aagtagccga gaaactgctc acaacgcgtc attggccgat
    24481 cgtcgacaga tacgtaggat gatccgtcgg cgggggttga agaccagttg ggcggtgaca
    24541 tgagcgcggg cgcgagcacg atcagcgatc gggcggcgga cacccgggtg accaccgcgc
    24601 gacgagtact gctcatcgcc gggattctcc tggtggcggc caatctccga ggtgcgctga
    24661 cctcggtggg cccgctgctg gagacgatca ggcgatccga aggactcagt gccgggcagg
    24721 cgggattgct cagcgcgctg ccgctgctga ccttcgcggt gttctccccg caggtgccgc
    24781 ggctcgctcg ccgggtcggc atggagcggc tgacctggtg cgcgttgctg gcactggccg
    24841 tcggcatcgt gctgcgctcg gtgccgctga gcggcatgct ctggctgggc acgatcctg
//
