LOCUS       NZ_FWXV01000005        22583 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Kibdelosporangium aridum strain DSM 43828, whole genome shotgun
            sequence.
ACCESSION   NZ_FWXV01000005
VERSION     NZ_FWXV01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium aridum
  ORGANISM  Kibdelosporangium aridum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900176515.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:02:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,283
            CDSs (total)                      :: 11,193
            Genes (coding)                    :: 11,032
            CDSs (with protein)               :: 11,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 3, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 38 of 161
            Pseudo Genes (incomplete)         :: 135 of 161
            Pseudo Genes (internal stop)      :: 6 of 161
            Pseudo Genes (multiple problems)  :: 17 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:58:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 53358
            Orig. end                         :: 75941
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FWXV01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22583
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22583
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22583
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12583](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12583)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     misc_feature    191..204
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     gene            complement(727..1125)
                     /locus_tag="B9C43_RS27535"
                     /old_locus_tag="SAMN05661093_05616"
     CDS             complement(727..1125)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF028506.5"
                     /locus_tag="B9C43_RS27535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05616"
                     /product="DUF5134 domain-containing protein"
                     /protein_id="WP_160096729.1"
                     /transl_table=11
                     /translation="MWFTIGCATAAGAERVTSGGHAVMSLAMVAMVWGVPLPLWLQVAV
                     FTAITVWFAGLATVPDRRHGLRAVHHALMGASMAWMVCAMTVPVGHQVMVVFAWYFLIA
                     TIPLLGKQVDALGHAAMSAGTGLMLLAM"
     gene            1279..1776
                     /gene="aroQ"
                     /locus_tag="B9C43_RS27540"
                     /old_locus_tag="SAMN05661093_05617"
     CDS             1279..1776
                     /EC_number="5.4.99.5"
                     /codon_start=1
                     /gene="aroQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005166526.1"
                     /locus_tag="B9C43_RS27540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05617"
                     /product="gamma subclass chorismate mutase AroQ"
                     /protein_id="WP_084429926.1"
                     /transl_table=11
                     /translation="MGGLAIGPVDPFGPLAELAVRRVMLSDLVAAAKFGTGQQIDDPVR
                     EQQILDAVVAESVRRGMPSGPPAGFFRAQIEASKVVQNGLFKRWERHPDQRPARTPDLA
                     TEVRPQLDLLTEQILGQLHATVELWRPTMLCGIWRLDDIVHSLDELHRHAVAVSLRPIF
                     AS"
     gene            complement(1896..2318)
                     /locus_tag="B9C43_RS27545"
                     /old_locus_tag="SAMN05661093_05618"
     CDS             complement(1896..2318)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032779.1"
                     /locus_tag="B9C43_RS27545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05618"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_084429927.1"
                     /transl_table=11
                     /translation="MRLAALAGAVLTTVALSATTANATPPSGVTGTIISKTTAGGKDYI
                     LREITLAAGGTTGWHHHEGTLYALVRSGTLTHNKADCSIDGIYEPGSVFVEPAGQSNIH
                     VGRNLGKTPVVLDVLYVLPEGAPLSVDEPNPGCDFQ"
     misc_feature    complement(2310..2312)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            2682..2942
                     /locus_tag="B9C43_RS27550"
                     /old_locus_tag="SAMN05661093_05619"
     CDS             2682..2942
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="B9C43_RS27550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05619"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_037267227.1"
                     /transl_table=11
                     /translation="MKPSTTPRVVVLDREQRELLRLLATGLPDTAIARRMSLAPRTLAR
                     RISSLYQMLQADNRFQAGAAAERLGLLAGARADEHPKSVAV"
     misc_feature    complement(2952..2967)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.24"
                     /tool="antismash"
     misc_feature    2953..2966
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.98"
                     /tool="antismash"
     gene            3028..3342
                     /locus_tag="B9C43_RS27555"
                     /old_locus_tag="SAMN05661093_05620"
     CDS             3028..3342
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS27555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_05620"
                     /product="hypothetical protein"
                     /protein_id="WP_143446636.1"
                     /transl_table=11
                     /translation="MRSRVIRIYQPWPTPVRAACYTDPAVLPEIDAWVDRLREQGLVPP
                     DVDFAIRDGKAGPVGVLGDHEGEHELRPTGFLVFGRGRLQVLDESAFFGQYHDPARDEI
                     "
     gene            3426..4277
                     /locus_tag="B9C43_RS27560"
                     /old_locus_tag="SAMN05661093_05621"
     CDS             3426..4277
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227001.1"
                     /locus_tag="B9C43_RS27560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05621"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_084429929.1"
                     /transl_table=11
                     /translation="MRYGIVLFTSDRGIAPAVAAAAAERAGLDSFYVPEHTHIPVKRES
                     PHPHTGDSSLPDDRYMRTLDPWVALATAASVTTRIRLATAVALPVESDPITLAKTIASL
                     DHLSGGRVTLGAGFGWNVDELTDHGVPGAKRRTVLREYLEAMRALWTDEEASYAGEFVS
                     FGPSWAWPKPAQAHIPVLIGAGGTEKTFTWIARSADGWITTPYEVDITDQVATLQAIWR
                     DAGRRGAPEVVALGGRPDPDRLAHLASIGVTEVVFGLPDRAADDVAAWIGRLGERLGLQ
                     PR"
     gene            4362..5966
                     /locus_tag="B9C43_RS27565"
                     /old_locus_tag="SAMN05661093_05622"
     CDS             4362..5966
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013739.5"
                     /locus_tag="B9C43_RS27565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05622"
                     /product="flavin monoamine oxidase family protein"
                     /protein_id="WP_084429930.1"
                     /transl_table=11
                     /translation="MPRTEMFRFVRQVAVDHAVAERLGMPVLEHREARLARAAEARTIS
                     RRDVLKIGGVLAGAAMLGLPRPASAATHPKVAIIGAGLAGLNAALTLADAGVKSTVYEA
                     SDRVGGRMFSERTYWDAGQIAEHGGEFIDTDHEAVRDLCVRFGLGLTDVRAAAPKDGKD
                     VLFFDGRYRSHKEFVEDFRPVYKALEADVENAPDAPTWDATTPAATALSNMSVAEWIAT
                     RVPDGWLARFLEEAYVVEYGRQADEQTAVNLVYMMIDQSDLENPNVWGASDERYHITGG
                     NQRLPEAIAAALPKGTIEHGWRLEAIKRNTDGSQTLTFEGGKTVTADHTILAVPLGVLK
                     HIDYRRAGFDARMKRAISELHMGYCTKLNMQFRERDWLGRGVWPGISNGASFTDLGYQQ
                     IWDATAGQAGTKGIAVQYGGGDGALRFRPSRPFLDSGNAYVRAAVRQNLDQFGKVIPGV
                     AQDWTGKATLAAWHLNPDSYGAYSCYPIGYCHRYAGYEGMRQGNIHIAGEHTSVDYQGY
                     MNGAAESGARAAAEILG"
     gene            5977..7434
                     /locus_tag="B9C43_RS27570"
                     /old_locus_tag="SAMN05661093_05623"
     CDS             5977..7434
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024910.5"
                     /locus_tag="B9C43_RS27570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05623"
                     /product="APC family permease"
                     /protein_id="WP_084429931.1"
                     /transl_table=11
                     /translation="MDRLKPNSVGLLGVVFMAVATAAPITAMTGNVPVAVAFGNGIGAP
                     AGYIFATVVLTVFSIGFVAMARRITSAGAFYGFISHGLGRVMGLASGLLAVLAYIVFEA
                     SIVGIFAYFADTTINAQLGLDLPWQLYAAIMLAVTAALSYFDIHLAAKVLGVFLIAEIA
                     VLALMAFGVLFHGGGPDGIPLDPVEPTAAFGGAAAGFGLFMAFWSWVGFESTAMYGEES
                     RNPKKIIPIATLVAVVGIGLFYVFVSWMAIAGNGLDESVALAAKSPLDLFFAPTEQTVG
                     HWAVVAFQWLMITGSFACGMAFHQCAARYLYALGREGLIWRPLGRTHPKHGSPFVASFT
                     QTGIAVVIVALFSLSGQDPYLGLYTLMALLGTMAILIVQALCSFAVVGYFWRRGGNKLT
                     TLLAPLLGGAGMITVVWLLFDNADAAAGPAARSTLFAAIPWIVAGVFAAGVLGALYLRK
                     AKPETYDRLGRIVLEDTEERTERIAAT"
     gene            complement(7365..8804)
                     /locus_tag="B9C43_RS27575"
                     /old_locus_tag="SAMN05661093_05624"
     CDS             complement(7365..8804)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020668079.1"
                     /locus_tag="B9C43_RS27575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05624"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_084429932.1"
                     /transl_table=11
                     /translation="MDTEVLIAGAGPTGLVLAIELARRGVDVRIVDKVDAYPTSSRGDA
                     LVPRTLTVFDDLGVLDEVLAAGHAKYPVQTYRDGALSHRRERITHTGQRPNMWLLGQAR
                     TEQLLRDRLAALGVRVQLGTAVTGLSQDAQAVTVRLNGEEIRAAYLVGADGGKSFVRHV
                     LGVPFPGTTDETVRMLICDVEIDGLDTTCAHWFAQGLALVPVSGQPPLFQLRAPLGADA
                     PQTTHSGVQALLDSRCGAGEVRLRDLRWSTVLRSNLRVAERFRIGRVFLAGDAAHVHPP
                     TGSYGLNTGVEDAYNLGWKLATALSNSECVALLDSYHQERHRVASQIHTMITGLTRTYA
                     SGDKVPPELDLSYRHSPLSVDERAKPGTLRAGDRAPDALVQARDGRLTRLFELFHGTHA
                     TVLAFGQESADPPNWPGEVRTYSVFPPGFGGEFTDHEGQAFGAYDVLPATQVLVRPDGY
                     VAAIRSVRSSVSSNTIRPSRS"
     gene            complement(8813..9778)
                     /locus_tag="B9C43_RS27580"
                     /old_locus_tag="SAMN05661093_05625"
     CDS             complement(8813..9778)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="B9C43_RS27580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05625"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_084429933.1"
                     /sec_met_domain="LANC_like (E-value: 1.2e-32, bitscore:
                     108.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITLDAITALVGEPRPAPQCVRPALADGGPGLVLAFNQLDRCLPG
                     QGWRAMAENYLDATVAGVHRLGGLGASPGMYGGLAGVAFAAWMLARDVPDIHESVVRQA
                     IARSRALGGGSQREVDLISGLTGTGAYMLCRRDEPALATVLTALAAASADLPPGMAHGS
                     SGPLALLCLAERAGVRVPGQRDAIATLALQHAVEMPGTTWCRGSAGMARALWHAGISLG
                     DPDMCDRAVSTVKAAHRQGATPDVGLCHGRAGLLQVTFRFASDTGDPELVAAMPKLAAE
                     LVTSAPDEPGFLDGTAGVVLALLAAVAPEPPDWDRALLLS"
     gene            complement(9851..9979)
                     /locus_tag="B9C43_RS59660"
                     /old_locus_tag="SAMN05661093_05626"
     CDS             complement(9851..9979)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS59660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_05626"
                     /product="hypothetical protein"
                     /protein_id="WP_268811593.1"
                     /transl_table=11
                     /translation="MQSDVLELQTLPETDTEQLNPVMCCDTDWTSGSCTDPPRCKE"
     CDS_motif       complement(9920..9979)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MQSDVLELQTLPETDTEQLN"
                     /locus_tag="B9C43_RS59660_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9851..9919)
                     /prepeptide="core"
                     /locus_tag="B9C43_RS59660_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-0.70"
                     /molecular_weight="2341.6"
                     /monoisotopic_mass="2339.9"
                     /core_sequence="PVMCCDTDWTSGSCTDPPRCKE"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MQSDVLELQTLPETDTEQLN"
                     /leader_location="[9919:9979](-)"
                     /alternative_weights="2359.6"
     gene            complement(10001..12583)
                     /gene="lanL"
                     /locus_tag="B9C43_RS27585"
                     /old_locus_tag="SAMN05661093_05627"
     CDS             complement(10001..12583)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="B9C43_RS27585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05627"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_200825713.1"
                     /sec_met_domain="Pkinase (E-value: 2e-19, bitscore: 65.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 5.2e-07, bitscore: 25.2,
                     seeds: 156, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.7e-44, bitscore:
                     145.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGTEAPGWTLQDGATWCMVTPALHTHRRQGWKLHVSAIASTAHH
                     VLEAVTPILAEHRCAFKFASCPRVLIDLTGVRAPRAQSGKFLTVYPTDDDQLRELAQRL
                     HEATIGLAGPAILSDRRYRPDSVVHYRYGSFTSARELNDEGFYEGQLLAPDGSFVPDKR
                     NPWFSPPEWAVPPFEQSARNGGTGRPVLLAGRYLVREAIRHANRGGVYRAEDQRTGEAV
                     LIKEARPHIGAGTSDGDARDWLRYEAHVLSKLAPLGVTPAVREVFESSGHVFLVEDLIE
                     GTSLTEWSIDQATRNGARMPLELMWRLARDLTRLVAQAHAAGFVVRDLKPSNVMMTPRN
                     EPVLIDLECAVELGAAVHVRGTAGFTAPEHLAAADGVKAGPEVDCFSIGATLLHTATGI
                     NPVLAEDTEPVRPVADRLAAIVGAAAPEHPALRALAPLVIGMTADVPDRWPLDKAVAFL
                     SAKPDVAAVEAPALNGVANRLSRDGFAYLAETIDVNAEYLWPRGRGVPAGDPCNVQLGA
                     GGVLAVLDRAVRTGAHPEVEPVLRSAAEWLGRRLTQPDRILPGLHFGRSGAVWALYDAA
                     RTLGDTALADQATAYALRIPLDWSNPDICHGLAGAGLAQVHLWWATGDRRFADRATECA
                     DRVLRLLENSASGVEWPLEHRRELAGCPSYGFGHGIAGVATFLLIAGRALDWPELVDIA
                     ASGGHALCAVAERDGELVLWPKGPGRTERMGLTLWCHGASGIGTFLIRLWQATGEQVFL
                     DHAERAARVVHRDRWRHSPSTCHGVAGNAQLLLDVADATGEAQYRYWAEEAVVCLATRA
                     TRRADRLLVPDETLREVQASYQVGLSGALDFLLRLEYGGGRAWLPDFE"
     gene            complement(12761..14134)
                     /locus_tag="B9C43_RS27590"
                     /old_locus_tag="SAMN05661093_05628"
     CDS             complement(12761..14134)
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (33-384). E-value: 6.2e-94.
                     Score: 306.7. Matches aSDomain:
                     nrpspksdomains_B9C43_RS27590_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013672520.1"
                     /locus_tag="B9C43_RS27590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05628"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_084429935.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.3e-90, bitscore:
                     298.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAYDAADLARSASEHLWMHFTRHSTFADTPPPVIVRGEGAYVFD
                     AEGKRYLDGLAGLFAVQVGHGREELAQAAAEQTRQLGYFPLWGTAHPKAVELAERLAAS
                     APGDINRVFFTVSGGESVETAWKLAKQYFKLTGKPTKHKVISRSLAYHGTSQGALSITG
                     IPAAKQDFEPLVPSAIKVPNTNIYRAPVFGDDPEAYGRWAADQIAAAIEMEGPDTVAAV
                     FLEPVQNTGGCFVPPPGYFQRVREICDQYDVLLVSDEVICAFGRLGHDFGAKRYGYQPD
                     IITVAKGLTSGYAPLGAVLVSDRLMEPYLQGTTTFLHGSTYGGHPVSCAVAIANLDLME
                     NEGIYDHVLSNEAAFRSTLDKLSDLPIVGDVRGAGFFYGIELVKDKETKETFSAEESER
                     VLRGFLSSALFDAGLYCRADDRAEPVIQFSPPLICDQQQFDEIEQILRKVLTEAWHLL"
     aSDomain        complement(12983..14035)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS27590_Aminotran_3.1"
                     /evalue="6.20E-94"
                     /label="B9C43_RS27590_Aminotran_3.1"
                     /locus_tag="B9C43_RS27590"
                     /protein_end="384"
                     /protein_start="33"
                     /score="306.7"
                     /tool="antismash"
                     /translation="VIVRGEGAYVFDAEGKRYLDGLAGLFAVQVGHGREELAQAAAEQT
                     RQLGYFPLWGTAHPKAVELAERLAASAPGDINRVFFTVSGGESVETAWKLAKQYFKLTG
                     KPTKHKVISRSLAYHGTSQGALSITGIPAAKQDFEPLVPSAIKVPNTNIYRAPVFGDDP
                     EAYGRWAADQIAAAIEMEGPDTVAAVFLEPVQNTGGCFVPPPGYFQRVREICDQYDVLL
                     VSDEVICAFGRLGHDFGAKRYGYQPDIITVAKGLTSGYAPLGAVLVSDRLMEPYLQGTT
                     TFLHGSTYGGHPVSCAVAIANLDLMENEGIYDHVLSNEAAFRSTLDKLSDLPIVGDVRG
                     AGFFYGIELVK"
     gene            complement(14234..14677)
                     /locus_tag="B9C43_RS27595"
                     /old_locus_tag="SAMN05661093_05629"
     CDS             complement(14234..14677)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226083.1"
                     /locus_tag="B9C43_RS27595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05629"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_380142719.1"
                     /transl_table=11
                     /translation="MLDDIAKQIIEQLQQDGRMPYSTIGKIVGLSEAAVRQRVQRLADA
                     GVIQIVAVTDPMQVGLFRQAMIAINVAGPIEPVADALAEMDEIDYVVVCAGRFDILCEV
                     ICTDDASLLELISTRIRAIPGVRNAETLVYLKLRKQSYQWGTR"
     misc_feature    complement(14729..14744)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.3"
                     /tool="antismash"
     gene            14883..16259
                     /locus_tag="B9C43_RS27600"
                     /old_locus_tag="SAMN05661093_05630"
     CDS             14883..16259
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226082.1"
                     /locus_tag="B9C43_RS27600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05630"
                     /product="APC family permease"
                     /protein_id="WP_084429936.1"
                     /transl_table=11
                     /translation="MTDTATPAKAALVPTEPRRLTRSIGVFGGTLLTLSCLTPASSLFV
                     VVPPLLGETGTGTALTIALAALLCIGVALCYAELGTLVPSAGGEYAMVGIVAGRFAGWM
                     MFVLSFIIVLIIPPVIALGTADYLHSVMDVDPRVAGAVVMLLGTLMGLLNLRANAWITG
                     IFLVLEIVAIAVVAFLGFGNAQRPASVLVNPTVTDPVEPLSTVTIIAGLAVALFVLQGF
                     TTAVYLSEEMHNPRRTVVRTVLWTLGIGALVVIIPVIAITLGAPDITTLTGGDIAAMVT
                     GWSNTGVGVFVSLSIALAIINAVIVMVIQNSRVLYASARDRAWPEVVNRAFSTVSNRFS
                     SPWVSTLVVGIGGAVLCFVPVETLSGVTSVVVAALYLGVAIATLTGRRGEHRGKPAWRM
                     AGWPVLPVLIALVLLYVVAQQAPLDLLITLGVLVAATVYWVAYLRPRPADRWVVTVPTE
                     "
     misc_feature    15117..15119
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16256..17707
                     /locus_tag="B9C43_RS27605"
                     /old_locus_tag="SAMN05661093_05631"
     CDS             16256..17707
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098512.1"
                     /locus_tag="B9C43_RS27605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05631"
                     /product="gamma-aminobutyraldehyde dehydrogenase"
                     /protein_id="WP_200825714.1"
                     /sec_met_domain="Aldedh (E-value: 2.8e-153, bitscore:
                     506.1, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPEILLSDKQVFRNFVNGKHADAADGRTLDIVNPATGEVYATS
                     PLSGQSDVDVAFAAAGTAFETWRDTTPAERQLALLRIADALEARSEEFVQREGENTGKP
                     MAVTRVEELPVAVDQIRFFAGAARVLEGKSAGEYLSGFTSYVRREPVGVCAQVTPWNYP
                     LMMAIWKIAPAIAAGNTLVLKPSDTTPATTVMLAELAAEFLPPGVLNIVCGDRDTGRSL
                     VTHPTPQMVSITGSERAGIEVAGAAAADVKRVHLELGGKAPVVVFDDADIAAAAKAIAA
                     AGYFNGGQDCTAATRVIAGAGVHDDFVAALAEAAKETRTGGPDEDVYYGALNNASQLAR
                     VSGFIDRLPDAATIHSGGSAVGERGYFYAPTVVSGLNQGDEIVTDEVFGPVITVQEFTD
                     EAEAVRLANGVRYGLASSVWTRDHATAMRMSRRLDFGCVWINTHIPMVAEMPHGGFKHS
                     GYGKDLSMYGLEDYTRIKHVMSALD"
     gene            complement(17679..18815)
                     /locus_tag="B9C43_RS27610"
                     /old_locus_tag="SAMN05661093_05632"
     CDS             complement(17679..18815)
                     /NRPS_PKS="Domain: Aminotran_5 (57-195). E-value: 5.1e-14.
                     Score: 43.9. Matches aSDomain:
                     nrpspksdomains_B9C43_RS27610_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009949609.1"
                     /locus_tag="B9C43_RS27610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05632"
                     /product="PLP-dependent aspartate aminotransferase family
                     protein"
                     /protein_id="WP_200825715.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.2e-12, bitscore:
                     41.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3.2e-09,
                     bitscore: 31.9, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.6e-12, bitscore:
                     42.4, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPAPGQPVTVPLYQTSNFRFESPQELTRAMSDPDSFAYSGYGN
                     PTNRALEQAMADLEQGEKALVTASGSSALSTVLQTILRHGDHIIAQKALYGGTVAMFNH
                     LADRWGIEVTYVDGVDPAEVSTALRPSTKLLFLETIANPIGHVPDLPALAAEAKQNGLL
                     TAVDSTFATPLLCRPIEHGADIVIHSATKYLGGHHDVVGGVAVFADEALYRQAWKHAIN
                     LGVVADPFAAWLIIRGLKTLPLRVNRACESAAMLAERMAAHPAVSAVHYPGLPTHASHA
                     RATKLLSGYGAIIATEVTDAQQFMGNLELIMNASSLGGTETTVMHPATTSHRHLTADEL
                     RTAGVSQNMVRIAVGVEHPDDLWADIEQALSPARTSRA"
     aSDomain        complement(18231..18644)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS27610_Aminotran_5.1"
                     /evalue="5.10E-14"
                     /label="B9C43_RS27610_Aminotran_5.1"
                     /locus_tag="B9C43_RS27610"
                     /protein_end="195"
                     /protein_start="57"
                     /score="43.9"
                     /tool="antismash"
                     /translation="LEQGEKALVTASGSSALSTVLQTILRHGDHIIAQKALYGGTVAMF
                     NHLADRWGIEVTYVDGVDPAEVSTALRPSTKLLFLETIANPIGHVPDLPALAAEAKQNG
                     LLTAVDSTFATPLLCRPIEHGADIVIHSATKYLG"
     misc_feature    18851..18865
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.3"
                     /tool="antismash"
     gene            18903..20318
                     /locus_tag="B9C43_RS27615"
                     /old_locus_tag="SAMN05661093_05633"
     CDS             18903..20318
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (145-437). E-value:
                     7.5e-34. Score: 109.3. Matches aSDomain:
                     nrpspksdomains_B9C43_RS27615_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020665910.1"
                     /locus_tag="B9C43_RS27615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_05633"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_143446638.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7.8e-33, bitscore:
                     109.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRPEDLVTRLGRWSAGRGPLYLLLAGRIRRLIDDGELQPGTPLP
                     PDRTLAAALAVGRTTVVSAYDLLAQEGKIVRRQGSGTKVAPAALRPERPADSANPLFMH
                     LLEPLDKIVQLTCAAPNVMPAAVTEAYAKALSVEVTDDIGYHPLGYYELRAALADRFTA
                     RGLPTKPGQILVTTGAQQALALLARLFVAPGDRVVVETPTYPGALEAFRESTADFVPVP
                     VGDADGLVRAMRARPAAVYVIPTHHNPTGSVMSTLTRQRLAAEAAELGVRLIEDEVLAD
                     LSFTDEAPLPVAAHGPAVTIGSLSKVVWGGLRIGWVRASESVIMQLARLKAVHDLGSNY
                     IGQVAAVSLVSSLDALRADRVSALYAQHAQLCASLREHLPSWEFTPAAGGQSLWVRLPH
                     GDAVSFAQLALRHGVAVLPGGSLDASGASKEFLRIPFLEPADVLAGAVVSLASAWREYN
                     PGVPGDSLTTLVV"
     aSDomain        19338..20213
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS27615_Aminotran_1_2.1"
                     /evalue="7.50E-34"
                     /label="B9C43_RS27615_Aminotran_1_2.1"
                     /locus_tag="B9C43_RS27615"
                     /protein_end="437"
                     /protein_start="145"
                     /score="109.3"
                     /tool="antismash"
                     /translation="HPLGYYELRAALADRFTARGLPTKPGQILVTTGAQQALALLARLF
                     VAPGDRVVVETPTYPGALEAFRESTADFVPVPVGDADGLVRAMRARPAAVYVIPTHHNP
                     TGSVMSTLTRQRLAAEAAELGVRLIEDEVLADLSFTDEAPLPVAAHGPAVTIGSLSKVV
                     WGGLRIGWVRASESVIMQLARLKAVHDLGSNYIGQVAAVSLVSSLDALRADRVSALYAQ
                     HAQLCASLREHLPSWEFTPAAGGQSLWVRLPHGDAVSFAQLALRHGVAVLPGGSLDASG
                     ASKEFLRIPFL"
     misc_feature    complement(21896..21910)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 gccgcggccg atattgacca gataagcatt gctgcgcatt ttcgccagcc gctcggcgtc
       61 gaacattccc tcggtttccg gtgtgtgcgg cacggtgatg atgaccaagt cggcttgacc
      121 gagccgctcg tccagtgcgg ccgcgggcag catttcggcg aatccttcga ccaggtcggt
      181 ctgccgcgcg tcgatgccga tcacgcgggt gccgaatgcc gaaagcatcc ggccgacctc
      241 tttgccgatc gccccgacgc ccacgatcaa cgcggtcgac tcggccatcg ccagcaccga
      301 cccgggatcc cagtcgggcg cccagttcga ctgagcctgt gcgcggacgt actgcggcag
      361 tccgcgcgcc agcgccagga cgagtgccat ggtgtgcgtg gcgacgtggt cggtgtacgt
      421 gtcccgcatg ttggtgacct ggaccgggtg ctcgatcagc ttggggtggt agaacccggc
      481 gggcggcccg gcttgcggag cctgcaacca tcgcagctgt ccggcgtgcg ccaacaactc
      541 ctcaggcagt gcaccgtagg ctgcgtccgc cgtacgcaac gcctcggcag cttcctcggc
      601 ggtgtccggt cgcagcacgc gaaggccggg gacggcctcg gcgagccgct gtggccacgt
      661 ggcggtctcg tcctgctgcg gcggcacaaa caccatggtg aagctcatgc ccggcattat
      721 ccctgctcac atcgccagca acatcaggcc ggtgcccgcg ctcatggcgg cgtggccgag
      781 cgcgtcgacc tgcttcccaa gcagtgggat cgtggcaatc aggaaatacc aggcaaaaac
      841 gaccataacc tgatggccga cgggaacggt catcgcgcag accatccacg ccatgctcgc
      901 gcccatgagc gcgtggtgca ccgcacgcaa cccgtgccgc cggtcaggca cggtggccaa
      961 gccggcgaac cacaccgtga tcgcggtgaa aacggctacc tggagccaga ggggcagcgg
     1021 gacaccccag accatcgcga ccatcgccag gctcatcacc gcgtggccgc cgctggtgac
     1081 ccgctcggcc ccggcagccg tggcgcagcc gatcgtgaac cacacgccgg tccccaggaa
     1141 taaaccggtc agcagccagt taaaagacat caagacacct ccatgtcaat acagaccgga
     1201 taggaggcgg aaactgatcg gggcggtacc gtggatttca tggggtacgt gaccaggttg
     1261 ggcagtgcgg ggtaggcgat gggcggcttg gccatcggac ctgtggatcc cttcggcccg
     1321 ctcgccgagc tggcggtgcg gagggtgatg ctcagcgatc tggtcgcggc cgcgaagttc
     1381 ggcacgggtc agcagattga cgacccggtg cgggaacagc agatcctcga cgccgtcgtg
     1441 gccgagtcag tgcgccgagg catgccctcg gggccaccgg ccgggttctt ccgcgcgcag
     1501 atcgaggcga gcaaggtcgt ccaaaatgga ctgttcaaac gatgggaacg gcacccggac
     1561 cagcggccgg ctcgcacgcc tgatctggcg accgaagtac gcccgcagct ggacctgctg
     1621 accgagcaga ttctgggcca gttgcacgcg acggtggagc tctggcggcc gacgatgctg
     1681 tgcgggatct ggcgcctcga cgacatcgtt cactcgctgg acgaactgca ccggcacgcg
     1741 gtcgcggtgt ccttgcgccc gattttcgct agctgaagcc gatgcgagag acgcaccggc
     1801 ttcacgcgtg cttcacaggg tttcggtcaa agcgttcgtc aaggacaagt ccggtgatgg
     1861 tcaagccgga tgacgattgg ccgaaaacca ggcggctact ggaagtcgca gccggggttc
     1921 ggttcgtcca ccgacagcgg cgcaccttcc ggcaggacgt acaggacgtc cagcaccact
     1981 ggtgtttttc ctaggttgcg gccgacgtgg atgttgctct gtccggcggg ctcgacgaac
     2041 accgagccgg gctcgtagat gccgtcgatc gagcagtccg ccttgttgtg cgtcagtgtt
     2101 ccgctgcgta ccagggcgta gagcgtcccc tcgtggtggt gccagccagt cgttccgccc
     2161 gcggccaggg tgatctccct gagaatgtaa tccttgccac cggcggtcgt cttgctgatg
     2221 attgtcccag tgaccccgct ggggggagtg gcgttggctg tggtcgccga caaagcgacc
     2281 gtggtgagca ccgcgccggc gagtgcggct aaccgcatga gttgtctcct ctcgtcatgg
     2341 tccattctgg gtccataaac catcatggac tgtccactct cgacatccat cctggcccga
     2401 tgcccgaatg gtcaccacac actgcgcgaa aactccaggc cgaacgcctt gctggccgcc
     2461 tttgcgggtg tagcgtcgtt cttgtcgcac tgcgatgggg tgtgacagcc tcaagaaacg
     2521 ctttaccgaa cagatatgag ggcagggctc gtatctgctc acaactcggt gccgatgccc
     2581 ccttcggcac cgggcagcgt atgaggcacg gcctggtgtg atgtcggcgc tggcatcaca
     2641 ccaggcgtcc taccgaccgc cgtatcggga gccgtaccga aatgaagccc tctaccactc
     2701 cacgtgttgt cgttctcgac cgggaacagc gggaattgct gcgcttgctc gccactggcc
     2761 tgccggacac cgcgatcgcc cgccggatgt cgctcgcgcc acggactctg gctcgccgga
     2821 tctccagcct gtaccagatg ctccaggcgg acaaccgttt ccaggccggt gccgcggccg
     2881 aacgcctcgg cctgctggcc ggtgcgcgcg cggacgaaca cccgaagtcc gtcgccgtct
     2941 gacgttctcg ttcgaacatg tgttcgaacc tgtgataagt tctccgtcgg tcttaccgtg
     3001 ctcgcgagcc gacggggaat ggcggacatg cgcagtcgag tgatcaggat ctaccagccg
     3061 tggccgacgc ctgtgcgggc cgcgtgctac accgatccgg ctgtgttgcc ggagatcgat
     3121 gcctgggtcg acaggttgcg ggagcaaggc cttgtcccgc cggacgtcga cttcgccatc
     3181 cgggatggca aagccggccc ggtgggcgtg ctgggtgatc acgaaggcga gcacgaactt
     3241 cggccgaccg ggttcctggt cttcggccgc ggcaggttgc aggtactgga cgagtcggcg
     3301 ttcttcggcc agtaccacga ccccgccagg gatgagatct gaaagaacac gttccagtcg
     3361 cgacccttgc tgcttggcat agcgggcatt gcgaaactga aacgtgttct aatactctgc
     3421 ctggtgtgcg gtatgggatc gtgctgttca ccagtgaccg tggcatcgcg cccgcggtgg
     3481 cggcggctgc cgccgagcgg gccggcctgg attccttcta tgtgccggaa catacgcaca
     3541 tcccggtcaa acgggagtcg ccgcatccgc acaccggcga ttcgtcgctt ccggacgacc
     3601 gctacatgcg gaccctcgat ccgtgggtcg cgctcgcgac cgcggcctcg gtgaccactc
     3661 ggatcaggct ggcgaccgcg gtggccctcc cggttgagag cgatcccatc acgctggcca
     3721 aaacaattgc cagtctcgac cacttgtccg gcggtcgggt gaccctgggt gcggggttcg
     3781 gctggaacgt ggacgaactc actgaccacg gcgttcccgg tgcgaaacgc cggaccgtcc
     3841 tgcgtgagta cctggaagcc atgcgtgcac tgtggactga cgaggaggcc agctacgcgg
     3901 gtgagttcgt gtcgttcggt ccgagctggg cgtggccgaa accggcgcag gcgcacatcc
     3961 cggtgctgat cggcgccggc ggtaccgaga agaccttcac atggatcgcg cggtcggccg
     4021 acggctggat caccacgccg tacgaagtgg acataaccga ccaagtggcc acgctgcagg
     4081 cgatctggcg ggacgccggg cgccgcggtg cgccggaggt cgtcgcgctg ggcgggcggc
     4141 ctgatccgga tcggttggcg cacttggcgt ccattggcgt cacagaggtc gtgttcggtt
     4201 tgcccgaccg tgccgcggat gacgtcgcgg cctggatcgg caggctcggt gaacggctcg
     4261 gccttcaacc gaggtaattc atcctcgcag ttgactttgg caacggattt cgtcgcaatc
     4321 gggcgttgac agtgcgagat tcgtgctgtt gcatcttcgc catgccgcgt acagagatgt
     4381 tccgcttcgt gcgtcaggtt gcggtggacc atgctgtagc cgagcgactt ggcatgcctg
     4441 tgctcgaaca ccgcgaggcg cggctggcgc gtgctgccga agcgcgcacg atcagccgtc
     4501 gcgatgtcct gaaaatcggt ggtgtgctgg caggcgccgc gatgctcggc ctgccgagac
     4561 ccgccagtgc cgcgacacat cccaaggtcg cgatcatcgg cgccgggctc gccgggctca
     4621 acgccgcgct gaccctcgcc gacgcgggcg tgaagtccac ggtgtacgag gcgagcgacc
     4681 gagtcggcgg ccggatgttc tcagagcgca cgtactggga cgctgggcag atcgccgagc
     4741 acggcggcga gttcatcgac accgaccacg aagctgtgcg ggacctgtgc gtccgctttg
     4801 gcctcgggct gaccgatgtc cgtgccgccg cgccgaaaga cggcaaggac gtgctgttct
     4861 tcgacggccg gtaccgctcg cacaaggagt tcgtcgaaga cttccggccg gtctacaaag
     4921 cgctcgaggc ggacgtcgag aacgcgccgg acgcaccgac atgggacgcg accacacccg
     4981 ccgcgacggc actgagcaac atgagcgtgg ccgaatggat cgcgacacgc gtgcccgacg
     5041 gctggctcgc ccggttcctc gaagaggcat atgtcgtcga atacggcagg caagccgacg
     5101 agcagaccgc ggtcaacctg gtctacatga tgatcgacca gagcgatctg gaaaacccga
     5161 acgtctgggg cgcgtccgac gagcgctacc acatcaccgg cggaaaccag cggctgcccg
     5221 aagcgatcgc ggccgcgttg cccaagggca cgatcgaaca cggttggcga cttgaagcca
     5281 tcaagcgcaa taccgacggc agtcaaaccc tgacgttcga gggcggcaag acggtcacag
     5341 cggatcacac gatcctggcc gtgccactcg gcgtgctgaa acacatcgac taccggcgcg
     5401 caggtttcga cgccaggatg aaacgtgcga tcagtgagct gcacatgggc tactgcacga
     5461 aactcaacat gcagttccgg gaacgcgact ggctgggccg tggtgtgtgg ccggggatct
     5521 ccaacggtgc cagcttcacc gaccttggct accagcagat ctgggatgcg acagcaggac
     5581 aagcgggcac gaagggcatc gcggtccagt acggcggcgg cgatggtgcc ctgcggttcc
     5641 gcccgtcgcg gccgttcctg gattcgggca acgcgtacgt gcgggcagcg gtccggcaga
     5701 acctcgacca gttcggcaaa gtcattcccg gcgtggccca ggactggacc ggcaaggcaa
     5761 cgctggccgc atggcatctg aacccggact cgtacggcgc ctacagctgc tatccgatcg
     5821 gctactgcca tcgctatgcc ggttacgaag gaatgcgaca aggaaacatc cacatcgccg
     5881 gtgaacacac ctcggtggac taccagggat atatgaacgg tgcggccgaa agcggtgccc
     5941 gcgccgccgc ggaaatcctc ggttagagga ggggaagtgg accggctcaa gcccaattcg
     6001 gtcggcctgc tcggtgtggt gttcatggcg gtggccactg cggcaccgat caccgcgatg
     6061 acaggcaatg tcccggtggc agtcgcgttc ggaaacggta tcggcgcacc ggccggttac
     6121 attttcgcga ctgtcgtgct gacggtcttc agcatcggat tcgtcgcgat ggcgcgccgg
     6181 atcacctcgg cgggcgcgtt ctacggcttc atctcccacg gcctgggccg ggtgatggga
     6241 ttggccagcg ggctattggc ggtgctggcg tacatcgtgt tcgaggcgtc gatcgtgggc
     6301 atcttcgcgt acttcgcgga caccacgatc aacgcccagc tgggtctcga cctgccgtgg
     6361 cagctctacg cggcgatcat gctggcggtg acggcggcgt tgtcctattt cgacatccac
     6421 ctggccgcca aggtcctcgg cgttttcctc atcgccgaga tcgctgtgct ggcactgatg
     6481 gcattcggag tgttgttcca cggcggcgga cccgacggca tcccgctcga tccggtcgaa
     6541 ccgacggcgg cgttcggcgg agcagcggcg ggattcggct tgttcatggc cttctggtca
     6601 tgggtcggct tcgagtcgac ggcgatgtac ggcgaggagt cccgcaaccc gaagaagatc
     6661 attcccatcg cgacactcgt cgcggtggtc ggcatcggac tgttctacgt tttcgtgtcg
     6721 tggatggcga tcgcgggcaa cggccttgac gagtcggtcg cactggcggc caagagcccg
     6781 ctggatctgt tcttcgcccc caccgaacaa acggttggtc actgggccgt ggttgccttc
     6841 caatggctga tgatcaccgg ttctttcgcg tgcggcatgg cattccacca gtgcgccgca
     6901 cggtacctct acgcgttggg acgcgagggc ctgatctggc ggccactcgg ccggacccac
     6961 ccgaagcacg gctcgccgtt cgtggcttcc ttcacccaga ccggaatcgc ggtcgtgatc
     7021 gtggccctgt tcagcctctc cgggcaggat ccttacctcg gcctgtacac cctgatggca
     7081 ttgctgggca caatggcgat cctgatcgtg caggcactgt gctcgttcgc cgtggtgggc
     7141 tacttctggc ggcgcggcgg caacaagctg acgactctgt tggctccctt gctcggcggc
     7201 gcaggcatga tcaccgttgt ctggctgttg ttcgacaacg ctgacgcggc ggcaggccca
     7261 gcggcgcggt ccactttgtt cgccgcgatc ccgtggatcg tcgcgggagt gttcgcagcc
     7321 ggtgtcctcg gcgcgctcta cctgcgcaag gccaaacccg agacctacga ccggctcggc
     7381 cggatcgtgt tggaggacac cgaagaacgc accgaacgga tcgccgcgac gtagccgtcc
     7441 gggcgaacca gcacctgcgt tgcggggagc acgtcgtaag cgccgaaggc ctgtccttcg
     7501 tgatcggtga actctccgcc gaaaccgggc gggaacacgc tgtacgtgcg tacttcaccc
     7561 ggccagttcg gcggatccgc ggattcctgt ccgaaggcca gcacagtggc atgcgtgccg
     7621 tggaagagct cgaacagccg agtcaggcgc ccgtcgcggg cctggacgag tgcgtctgga
     7681 gcacggtcac cggcacgcag ggttcctggt ttggcgcgtt cgtcaaccga cagtgggcta
     7741 tgacggtaac tcaggtcgag ctccggcggt actttgtcac cgctggcgta agtccgcgtc
     7801 agaccggtga tcatggtatg gatctgactc gcgaccctgt gccgctcctg gtggtagctg
     7861 tccagcaacg ccacgcattc cgaattggac agtgcggtgg cgagtttcca gccaaggttg
     7921 tacgcgtcct cgacaccggt gttgagcccg taacttccgg tgggcggatg gacatgtgcg
     7981 gcgtcaccgg cgaggaagac acggccgatc cggaagcgtt ccgcgacacg gagattggac
     8041 cgcagcacgg tcgaccacct gaggtcgcgc aggcggactt cgccggcgcc gcaacggctg
     8101 tccagcaggg cttgtacgcc cgagtgtgtg gtttgcgggg cgtccgcacc gagtggtgcc
     8161 cgcagttgga acagcggtgg ctggccggaa acgggcacga gcgcgagccc ctgcgcgaac
     8221 caatgcgcgc acgtcgtgtc caatccgtcg atctcgacat cgcagatcaa cattcggacc
     8281 gtttcgtcgg tcgtgcccgg aaacggcacg ccgagtacgt gacgcacaaa gctctttcca
     8341 ccgtcggcgc cgacgaggta agcggcacgt atctcctcgc cgtttagacg caccgtcacc
     8401 gcttgggcgt cttgggacaa accggtcaca gcggttccca gctgaacccg cacaccgagc
     8461 gcggcgagcc ggtcccggag cagctgttcg gttctggcct gacccagcaa ccacatattc
     8521 ggacgttgcc cggtgtgcgt gatcctctcc cgacgatgcg acagcgcgcc atcgcggtag
     8581 gtctgtaccg ggtacttcgc gtgacctgct gccaagacct cgtcgaggac gccgagatcg
     8641 tcgaagacag tcaacgtccg ggggaccagc gcgtcgccgc gtgagctcgt cggatacgca
     8701 tcgaccttgt cgactatccg cacgtcgacg ccgcgccgag ccagctcgat cgccagcacg
     8761 aggccggtcg gtccggcccc ggcgatcaac acttcggtgt ccatgtccct cctcacgaca
     8821 gcagcagcgc gcggtcccag tccggcggct ccggtgcgac ggcggcgagc agtgcgagca
     8881 ccacacctgc tgtgccgtcg aggaaacccg gctcatcggg cgcggacgtc acgagctcgg
     8941 ctgcgagctt cggcatggcc gcgacgagct caggatcgcc ggtgtccgag gcgaaccgga
     9001 aggtgacctg aagcaggccg gcccttccgt ggcagaggcc gacgtccggc gtcgcgccct
     9061 gacggtgtgc ggctttgacc gttgacaccg cacgatcgca catgtccggg tcaccaaggg
     9121 aaatccccgc gtgccacagc gcgcgggcca taccggcgct gccacggcac cacgttgtcc
     9181 ctggcatctc gacggcgtgc tgcaaagcca gcgtggcaat ggcgtcccgc tgtcccggga
     9241 cgcgcacgcc tgccctttcg gccaaacaaa gcaaggcaag cgggccggag ctgccgtggg
     9301 ccatacctgg cggaaggtcc gcactcgcag cggccagcgc tgtcaacacg gtcgcgagcg
     9361 ccggttcgtc acgtcggcac agcatgtacg cgccagttcc ggtcagtccg gagatgaggt
     9421 cgacctcgcg ttgactgccg ccaccaagtg cgcgagatcg tgcgatggct tgccgtacca
     9481 cgctttcgtg tatgtccggc acgtcccgcg ccagcatcca cgcggcgaag gcgactccgg
     9541 caagcccgcc atacattccc ggtgacgcgc cgagcccacc gagccggtgg acgcccgcga
     9601 cggtcgcgtc gagatagttc tcggccatgg cacgccagcc ctgccccggc aggcagcgat
     9661 cgagctggtt gaaggccagc acgagaccag gcccgccgtc agcgagggca ggccggacgc
     9721 actgcggcgc cggacgcggc tcgccgacga gtgcggtgat ggcgtcgagc gtgatcatgg
     9781 ttctccgtga tcgatggagc cgggttctgc gcggccgcgc gacaggtggc cgcgcagaac
     9841 agcgccgccg ttattcctta cagcgcggcg gatcggtgca cgaaccgctg gtccagtcgg
     9901 tgtcgcagca catcaccggg ttcaactgct cggtgtcggt ctccggcagc gtctggagtt
     9961 caaggacgtc actctgcatc tcgctctcac ctcctcaagg tcactcgaag tccggcagcc
    10021 acgctcggcc accgccgtat tcgaggcgga gcaggaaatc cagcgccccg gacaagccga
    10081 cttggtagct ggcctggact tcgcgcaatg tctcgtcggg taccagcaac cggtcggcac
    10141 gccgggtggc tcgcgtcgcg aggcacacca ccgcttcctc cgcccaatac ctgtactgcg
    10201 cctcgccagt cgcgtcggcg acatcgagca acaactgcgc attgcccgcg acgccgtggc
    10261 acgtactggg gctgtgccgc cagcgatccc gatggaccac gcgggcggct cgctcggcgt
    10321 gatcgaggaa cacctgttca ccggtcgcct gccacagccg gatcaggaag gtgccgatgc
    10381 cgctggcgcc atggcaccac agtgtcaggc ccatccgctc agtacgacca ggccctttgg
    10441 gccacaacac caattccccg tcgcgctcgg ccaccgcgca caacgcatgg ccgccggacg
    10501 ccgcgatgtc caccagttca ggccagtcca gtgcgcgccc ggcgatgagc aggaacgtgg
    10561 caacgcccgc tattccgtgt ccgaagccgt aactcgggca tccggcgagc tcccggcgat
    10621 gttccagcgg ccattccaca ccgctcgccg agttctcgag tagacggagc actcgatccg
    10681 cgcattccgt ggctcggtcg gcgaaccgtc gatccccagt cgcccaccag aggtgcacct
    10741 gggcaagacc agcgccggcc agcccgtggc agatgtcggg attggaccag tccaacggaa
    10801 tgcgcagggc atacgcggtg gcctggtcgg ccagcgcggt gtcaccgagc gtccttgccg
    10861 cgtcatacaa cgcccacact gcgccggacc gtccaaagtg gaggccagga aggatccggt
    10921 caggttgggt cagtcgtcgt cccaaccact cggccgcact ccgcagcacg ggttcgacct
    10981 cgggatgcgc ccctgtccgg acggcacggt cgagcaccgc gagcactcca ccggcaccga
    11041 gctggacatt gcagggatcg cccgcaggca cgccacggcc acggggccac aggtattcgg
    11101 cattcacgtc gatggtttcg gccagataag caaacccgtc acgcgacaac cggttggcga
    11161 caccattcag tgcgggagcc tcgacagcgg ctacatctgg cttggcactg agaaatgcga
    11221 cggccttgtc cagcggccac cgatccggca cgtccgcggt catgccgatg accagcgggg
    11281 cgagggcacg cagcgccgga tgttccggcg ccgcggcgcc gacgatcgcg gcgagccggt
    11341 cagcgaccgg cctgactggc tcggtgtcct cggccagcac cggattgatt cccgtcgcgg
    11401 tgtgcagcag tgtcgcgccg atgctgaagc agtccacttc gggcccggcc ttgacaccgt
    11461 cggcggcagc gaggtgttcg ggcgcggtga acccggccgt gcccctgaca tggacggcgg
    11521 caccgagctc gaccgcgcat tccagatcga tcagcaccgg ctcgttccgt ggcgtcatca
    11581 tcacgttgct gggcttgaga tcccgtacga cgaatccggc ggcgtgtgcc tgtgccacaa
    11641 gccgggtgag gtcacgggcc agccgccaca tcagctccag tggcatgcgc gcgccgttgc
    11701 gcgtcgcctg gtcgatcgac cactcggtca ggctcgtgcc ctcgatcagg tcctcgacaa
    11761 ggaagacatg gccactggac tcgaagacct ctcgcaccgc cggcgtcacc ccgagcggag
    11821 cgagtttgct cagcacgtgc gcctcatacc gcagccagtc ccgggcgtcg ccgtcgctgg
    11881 tccccgcgcc gatgtgcggg cgcgcctcct tgatcagcac cgcctcgccc gtgcgctggt
    11941 cctcagcccg gtagaccccg ccccggttgg cgtgccgaat tgcctcacgg accagataac
    12001 ggcctgcgag cagcacaggt cggccggtgc cgccgtttcg ggcagactgc tcgaacggcg
    12061 gcaccgccca ttcgggaggc gagaaccacg gattgcgctt gtctgggacg aagctgccgt
    12121 cgggagccag cagctgcccc tcgtagaagc cttcgtcgtt cagttcgcga gcggacgtga
    12181 agctgccgta gcggtagtgc acgacgctgt ccggccgata gcgccgatcg gacaggatgg
    12241 ccggtccagc caggccgatc gttgcctcgt gcaggcgctg agccagctca cgcagctggt
    12301 cgtcgtcagt gggatagacg gtgaggaact tgcctgactg ggcacgcggc gcccgcacgc
    12361 cggtcaggtc gatgagaacc cgcgggcagg aagcgaactt gaacgcacaa cggtgttcgg
    12421 ccaggatcgg tgtcacggct tcgaggacgt ggtgggccgt cgaggcgatc gccgaaacgt
    12481 gcagtttcca gccctgcctg cggtgtgtgt gcagggcagg cgtcaccatg caccacgttg
    12541 ccccgtcctg gagtgtccac ccgggagcct cggtgcccag cacccgccgg actatcgcct
    12601 ggtagtccga cgatgttgcc gttgtcaggc tggacagtgc gccaccccct tgccggaatt
    12661 acctgtccga caaggtaacg acgcgtgacg gtgattctct ctcccgaagg ggcggcagtt
    12721 cgggagtgcc cgttcatcgc ccccttcggg cggcgccaag tcagagcagg tgccacgcct
    12781 cggtgagcac cttgcgcagg atctgctcga tctcgtcgaa ctgctgctgg tcgcagatca
    12841 gcgggggcga gaactggatc accggctcgg cgcggtcgtc ggcacggcag taaagcccgg
    12901 cgtcgaacag ggcactggag aggaagccgc gcaacacgcg ctcggactcc tcggcgctga
    12961 aggtctcctt ggtttccttg tccttcacca gctcgatgcc gtagaagaac ccggcgccac
    13021 ggacgtcgcc gacgatcggc aagtcactca gtttgtccaa cgtggaccgg aaagctgcct
    13081 cattggacag cacgtggtcg tagatcccct cgttctccat cagatccagg ttcgcaatgg
    13141 cgacggcaca cgacaccggg tgtccgccat acgtcgagcc gtgcaggaat gttgtcgtgc
    13201 cttggagata cggctccatc agccggtcgc tgaccaggac cgcgcccagc ggggcgtatc
    13261 cggacgtcag tcctttggcg acggtgatga tgtcgggctg gtaaccgtac cgcttggcgc
    13321 cgaagtcgtg tcccagacgg ccgaacgcgc agatgacctc atcggacacc agcagaacgt
    13381 cgtactggtc gcagatctcg cgcactcgct ggaaatagcc aggcggtggc acgaaacacc
    13441 cgccggtgtt ctgcaccggc tcaaggaaaa ccgccgcgac cgtgtccggg ccttccatct
    13501 cgatcgccgc ggcgatctgg tcggcggccc aacggccgta cgcctcaggg tcgtcgccga
    13561 acaccggtgc gcggtagatg ttggtgttcg gcaccttgat cgcactgggc accaacggtt
    13621 cgaagtcctg tttggccgcc gggatgcccg tgatggacag tgcgccctgc gacgtcccgt
    13681 ggtacgcgag cgagcggctg atcaccttgt gcttggtggg tttgccggtc agcttgaagt
    13741 actgcttggc cagcttccac gccgtctcga cggactcgcc gccgctcacc gtgaagaaga
    13801 cccggttgat gtcacccggt gcggacgcgg ccaaacgctc ggccaactcg accgctttcg
    13861 ggtgggccgt gccccacaac gggaagtagc ccagttgacg cgtctgctcg gcggctgcct
    13921 gcgcgagttc ctcgcggccg tggccgacct gcaccgcgaa caggcctgcg aggccgtcga
    13981 ggtagcgctt gccttcggcg tcgaagacgt aggcgccctc gccgcgcacg atcaccggcg
    14041 gcggcgtgtc agcgaaggtg gagtggcgcg tgaagtgcat ccacaggtgc tcactcgcgg
    14101 atcgggccag gtcggcggcg tcgtaggcgg tcatgcctgc tttatcgcac actcgctacg
    14161 gatacgcaag taaatcaccc ttgcgaccga tgtttccggt attcagaccg tgatcaaact
    14221 acggattccg tagtcaccga gtgccccact gataggactg cttgcgcagc ttcaggtaga
    14281 cgagggtctc cgcgttgcgc acgccgggga tcgcgcggat ccgggtggag atcagctcga
    14341 gcaggctggc gtcgtcggtg cagatgacct cgcagaggat gtcgaaccgg cccgcgcaga
    14401 ccaccacgta gtcgatctcg tccatctcgg cgagcgcgtc ggcgacgggc tcgatcgggc
    14461 cggccacgtt gatcgcgatc atcgcctggc ggaacagccc gacctgcatc ggatcggtca
    14521 ccgcgacgat ctggatcacg ccggcgtcgg ccagtcgctg cacccgctgg cggaccgcgg
    14581 cttcggacag cccgacgatc tttcctatcg tcgagtacgg catccggccg tcctgctgca
    14641 gctgctcgat gatctgtttg gcgatgtcgt cgagcagagg ggccgctgtc cgctctggtg
    14701 ccgtgttctt ccggttcacg ctggcattat gaccggtcgg tcagaaaggc tcgccggtcc
    14761 ggcggatccg ggacgtgtcg cgacgtaaac aacggatttc gtcggcgata ggccgttgac
    14821 attgcggtat ccgcgttgtt ttatgcgtca caccacggtg acgtgaggcg aggagagtat
    14881 ggatgaccga tacggcgact cccgccaagg ccgcgctcgt ccccaccgag ccgcggcggc
    14941 tgaccagatc gatcggcgtg ttcgggggaa cgctgttgac gttgagttgt ctgactccgg
    15001 cgtcttcgct gttcgtggta gtgcctccgc tgctcggcga aaccggcacc gggacagcgt
    15061 tgaccatcgc gctggccgcg ttgctctgta tcggcgtggc cttgtgttac gcggagttag
    15121 gcacgctcgt gcccagcgcc ggtggtgaat acgcgatggt gggcatcgtc gccgggaggt
    15181 tcgccggctg gatgatgttc gtgctgtcgt tcatcatcgt gttgatcatt ccgccggtca
    15241 tcgcgttggg cacggcggac tacctgcatt ccgtgatgga cgtggatccg cgggtcgcgg
    15301 gggcggtcgt catgctgctg ggaaccctga tgggcctgct caacctgcgt gccaacgcct
    15361 ggattaccgg catcttcctg gttctggaga tagtcgcgat cgccgtggtg gcgttcctcg
    15421 gcttcggcaa cgcacagcgc ccggcctccg tgctggtcaa ccccaccgtc accgacccgg
    15481 tcgagccgct cagcacggtc acgatcatcg ccgggctagc cgtcgcgctg tttgtcctgc
    15541 aagggttcac caccgctgtc tacctgtccg aggagatgca caacccacgc cgcacggtcg
    15601 tccggaccgt tctgtggacg ctcggcatcg gcgcgttggt ggtgatcatc cccgtcatcg
    15661 cgatcacgtt gggagcgccg gatatcacga cgctcaccgg cggcgacatc gcggcgatgg
    15721 tcaccggctg gagcaacacc ggggtcggcg tgttcgtcag cctcagcatc gcgttggcga
    15781 tcatcaacgc ggtgatcgtc atggtcatcc agaactcccg cgtgctgtac gcctccgccc
    15841 gtgaccgcgc ctggccggag gttgtgaatc gcgcattcag tacggtcagc aaccggttct
    15901 cgtcgccatg ggtgtccaca ttggtcgttg gtatcggcgg cgctgtgctg tgtttcgtgc
    15961 cagtggagac gctcagcggc gtcaccagcg tcgtggtcgc cgcgctctac ctgggcgtcg
    16021 ccatcgccac gttgacaggg cgccggggcg agcaccgcgg caagcctgcg tggcgaatgg
    16081 cgggttggcc ggtgctgcct gttttgatcg cgcttgtcct gctttacgtc gtggctcagc
    16141 aggcgccgct cgatctgctg atcacgctcg gggtgctcgt cgcggctacc gtgtactggg
    16201 tggcctacct tcgcccgcga ccagcggacc gctgggtcgt caccgttccg accgaatgac
    16261 atcaccggag attctgttgt ctgacaagca agtcttccgc aacttcgtca acggcaagca
    16321 cgccgacgcg gccgacgggc ggacgctcga catcgtcaac ccggcgaccg gcgaggtcta
    16381 cgcgacctcc ccgctgtccg gtcagtccga tgtggacgtc gcgttcgctg cggccgggac
    16441 cgcgttcgag acctggcggg acaccactcc ggcggaacgc cagctggcgt tgctgcgaat
    16501 cgccgacgcc ctggaggcgc ggtccgagga gttcgtccag cgtgaaggcg agaacaccgg
    16561 caagccgatg gccgtgaccc gggtcgagga gctgccggtc gcggtcgacc agatccggtt
    16621 cttcgcaggc gcggcccgcg tactggaagg caagtcggcc ggggagtacc tgagcggctt
    16681 cacctcgtac gtccgtcgcg agcccgtcgg cgtctgcgcg caggtcacgc cctggaacta
    16741 tccgctgatg atggcgatat ggaagatcgc gcccgcgatc gccgccggga acaccttggt
    16801 actcaagccg tcggacacca caccggcgac cacagtgatg ctggccgagc tggccgcgga
    16861 gttcctgccg cctggcgtgc tcaacatcgt ctgcggtgac cgggacaccg gccgatccct
    16921 ggtcacgcac cccacgccgc agatggtgtc gatcaccggc tcggaacgcg ccggcatcga
    16981 ggtcgcgggc gccgccgcgg ctgatgtgaa gcgcgtacac cttgaactgg gcggcaaagc
    17041 tccggtcgtg gtgttcgacg acgccgacat cgccgcggcc gcaaaggcaa tcgctgcggc
    17101 cgggtacttc aacggtggcc aggactgcac cgccgcgacc cgggtgatcg cgggcgcggg
    17161 cgtacacgac gattttgtcg ctgctcttgc cgaggccgcc aaggaaaccc gaaccggcgg
    17221 gcccgacgag gacgtctact acggcgcact gaacaacgca tcccagctcg cccgggtcag
    17281 cggcttcatc gaccgccttc cggatgccgc aaccatccac agtggaggat cggcggtcgg
    17341 cgagcgtggc tacttctacg cgccgacggt ggtttccggc ctgaaccaag gcgacgagat
    17401 cgtcaccgat gaagtgttcg gcccggtcat caccgtgcag gagttcaccg acgaggccga
    17461 ggccgtgcgg ttggccaacg gcgtgcgcta cggcctggcc tcatcggtgt ggacgcgcga
    17521 tcacgccacc gcgatgcgga tgtcccggcg gctggacttc ggctgcgtgt ggatcaacac
    17581 gcacatcccg atggtggccg agatgccgca cggtggcttc aagcactcag gctacggcaa
    17641 ggacctgtcc atgtacggcc tcgaggacta caccaggatc aagcacgtga tgtccgcgct
    17701 ggactgagcg cttgctcgat gtcggcccac aggtcgtcgg gatgttcgac acccacggcg
    17761 atcctgacca tgttctggct gacaccggcg gtccgtagct cgtcggcggt caggtgccgg
    17821 tgggacgtgg tcgccgggtg catgacggtg gtttccgtgc caccgaggga agacgcgttc
    17881 atgatcagtt ccaggttgcc catgaactgc tgtgcgtcgg tgacttcggt cgcgatgatg
    17941 gcgccgtaac cgctcagcag tttggtcgcc ctggcatgac tggcgtgtgt cggcaggccc
    18001 ggatagtgca ctgcggacac cgctggatgc gccgccatgc gttccgccag catggcggcg
    18061 ctctcgcagg cacggttgac cctgagcggc aatgtcttga ggccacggat gatcagccat
    18121 gccgcgaacg ggtctgcgac cacgccgagg ttgatcgcgt gcttccaggc ttgccggtaa
    18181 agggcttcgt cggcgaacac ggcgacaccg ccgaccacgt cgtgatgacc gcccaggtac
    18241 ttggtcgccg agtggatcac gatgtcggcg ccgtgttcga tcggccggca cagcagggga
    18301 gtggcgaacg tgctgtcgac cgcggtgagc aggccgttct gcttggcctc ggcggccagc
    18361 gcgggcaggt ccggcacgtg cccgatcggg ttcgcgatcg tctccaggaa cagcagcttg
    18421 gtgcttggcc gcagtgccgt gctcacctcg gccgggtcga cgccgtcgac ataggtgact
    18481 tcgatacccc atcggtcggc gaggtggttg aacatcgcga ctgtgccgcc gtagagcgcc
    18541 ttctgggcga tgatgtggtc gccgtggcgc aagatcgtct gcagtacggt gctgagcgcg
    18601 ctcgatcccg acgctgtgac cagcgctttc tcgccctgtt ccaagtcggc catggcttgc
    18661 tcaagcgctc ggttggtcgg gttgccgtac ccgctgtagg cgaaggagtc cggatctgac
    18721 atggccctgg tcagctcttg cgggctttcg aaccggaagt tggacgtctg gtagagcggc
    18781 acggtcacgg gctgaccagg cgcaggggcg gtcaagcggg ctgctcgtgt ctcacggtgc
    18841 atgatcagag tcttgtcgga aaattggccc tatggcagag ccaatctggc agaattggtt
    18901 tggtgacgag accggaggac ctggtgaccc ggctcggccg ctggtcggct gggcgtggtc
    18961 cgctgtacct gctgctcgct gggcggatcc ggcgcctgat cgacgacggc gagctgcaac
    19021 cgggcacacc actgccgccg gatcgcacgt tggccgcggc tctggcggtt ggccggacga
    19081 ctgtggtgtc cgcgtacgac ctgctggcgc aggagggcaa gatcgtgcgg cggcagggca
    19141 gcgggacgaa ggtcgctcca gccgcgttgc gcccggagcg tcctgccgac agcgcgaacc
    19201 cgttgttcat gcacctgctc gaaccgctcg acaagatcgt ccaactgacg tgcgcggcgc
    19261 cgaacgtcat gcccgcggct gtcaccgagg cctacgccaa ggcgctgtct gtcgaggtca
    19321 ccgacgacat cggctaccac ccactcggtt actacgaact gcgggccgcg ctggcggacc
    19381 gcttcaccgc gcgcggactg ccgaccaaac ccggccagat cctggtgaca acgggcgcgc
    19441 agcaagcttt ggcattgcta gccaggttgt tcgtcgcgcc aggggaccgg gttgtggtgg
    19501 agacaccgac ttatcccggt gcgctggaag ctttccggga gtccactgcg gacttcgtac
    19561 ctgttccggt tggtgatgcc gacgggctgg ttcgtgcgat gcgggcgcga ccggcggccg
    19621 tgtacgtgat tcccacgcat cacaacccga ccgggtcggt gatgtccact ttgacccgtc
    19681 agcgccttgc cgccgaagcc gcggagctgg gcgtccggct gatcgaggac gaggtgctcg
    19741 ccgacctgag cttcacggac gaggccccgt tgcctgtcgc ggctcacggt ccagcggtga
    19801 cgatcgggtc gttgagcaag gtcgtgtggg gcgggctgcg gatcggctgg gtccgggcgt
    19861 ccgaatcggt gatcatgcag ctggcgcggc tcaaggccgt acacgatctg ggcagcaact
    19921 acatcggcca agtcgccgcg gtgtccctgg tgtcttcttt ggacgctctg cgagctgatc
    19981 gcgtctcggc gttgtatgca cagcatgcgc agctttgcgc ttcgttgcgg gaacatcttc
    20041 cgtcgtggga gttcaccccg gctgccggcg gccagagctt gtgggtccgg ctgccgcacg
    20101 gcgacgcggt ttcgttcgct cagttggcgt tgcggcacgg cgtcgccgtg ttgccaggcg
    20161 gatcgctgga cgcctccggc gccagcaagg aattcctgcg gattccgttc ctggaacccg
    20221 cggatgtcct tgctggcgcg gtggtgtcgt tggcctcggc ttggcgcgag tacaaccccg
    20281 gcgtccccgg cgactcgctt acgaccctag tcgtgtgaac gtcagctcga tgctcgcctt
    20341 gtgggcgtgc agctggtact gcgggagcac acctgggccg caagcagctg tgcccacgcc
    20401 gttctgggcg atgtcgaggt tcagatagat ccagtcggtg ggcgtcagat cgatcgtgtg
    20461 ctcggccgcg tcgaggtctt cggacgtcca ccgcctcgcg gtgaattcga agtcgccttc
    20521 gatcctgatg ccctcgccgg tgtcgttggt gagctcggcc cagcggactt cagtgcggtt
    20581 gccgttctct tgcgggacaa cgtacggcgt ctgcatttcg tccactgtgt acttgtatct
    20641 gccgacggcc gcggcttgcc tggtgtcagc gtaggcttcg ttcgggcctc ggccgaacca
    20701 ctcgacgttg ccgtattcct tgggcagggc catcctgagg cccagacggg gcaacgtgcc
    20761 cggccattcg ccgtccggct cgatgtcgac tttgaggttc agcgtggttt cgtcgccggt
    20821 ccacgtgtag gtgacgaaca tgccgaacgc tctcgcgggc ggggccaccc gagtcttcgt
    20881 cgtcccgcct tccacgctga tcaggcggtg ctgcaggcga tgcaggccgt tcttgcgcca
    20941 ggtttcctcg tcggacggct tgtcgttctc ggtcggcgcc cgccacaggt ccagcttggg
    21001 cgcttcgatc gggatcccgc cgatgtcccg gggtacttct cggggctctc ggcttccttg
    21061 ggtctgctgg cgggctttga cgttgacttg tccccacgcg atcgggtgat tcgcgttcgc
    21121 ccacgcggcg tccttggcca gcgtggcggt caccgtcacc cacgattcgc cttgggtctc
    21181 aggcattttc ggcaggtcaa gggtgacttc ctggcccggc tggacggtgg gggtgtgcag
    21241 gatgccggag gcgacctcga ccccttcatc ctccagtttc caagcgaaac tcagctgctc
    21301 aagcccggag aagtcgtagt gattagccac aacaaccttc aagttgtcca cagctcccag
    21361 cgaacccttc tccccatccc caccccccga tacgctggat gcggggtgcc ccccgggaag
    21421 ggcgggggct gcctgggggc tggtcgatgg tggaggggag tcgaaatctc cttggggggc
    21481 aacggtttcg gcggaattcg acgatgctgg ggacttcgat gccgctgggt ttgcggtgcc
    21541 gggtgtcccg tgggtctgtg tcgttgggat ggcggcgccg ggagccgaga tgcggactgg
    21601 ttcgaagatc ttcttgagct cgtgcaagcc tggagaaggc gtgcgatccg ggaacaccag
    21661 gccgtcgatc acgaagctgc cgtcgtggat cgtctcgccg aagtcgccgc catacgcgaa
    21721 atacggtcgg ccctccgaat ccacctgacg gatgccgtgg tcgagccatt cccagatgaa
    21781 gccgccctgg caccgcgggt acttctcgaa aagctcccgg tactccagca acccgccagg
    21841 cccgttgccc atcgcgtggg cgtactcgca ttggatgaac ggcaactcgg tcgtctggcc
    21901 gatctcgtcg acctccgcgt gtgaggcgta catccggctg tagacgtcga catactcgca
    21961 tgcggcgtcg ccctcgtagt gcacgggccg cgtcgagtca cgggaacgag tccacgaggc
    22021 catggcggcg agattgcgac cggtgtgagc ctcgttgccg agtgaccaca tgatgatgct
    22081 gggatggttc ttgtcgcgct cgaccatccg cttcatccgg tcgaggtacg ccgcttccca
    22141 ctgcgggtcg tcgctgggat tgcgttccca gccgacctct gagaaaccgt gcgtctcgag
    22201 gtcgcactcg tcgatcaccc acaacccgta ctcgtcgcac aggtcgagga aggccgggtg
    22261 cggcgggtaa tgcgaagttc gcacggcatt gatgttgtgc tgcttcatca tcagcacgtc
    22321 ggccaacgca gtctcatacg gcacagcacg gcccaagtcc gggtggtgtt cgtgccggtt
    22381 gacacccttg agaaggatac gcttgccgtt gactttgagc tgaccgtccg caatggtcac
    22441 cgtgcggaaa ccgatgcgca gcggcacgcg ttcgtggtcc gaagccaggt atccctcgta
    22501 caaccgagga gtttccgcgg tccacggctc cacgacaccc gcgtcgatcg gcaagtcggt
    22561 tgatgcccgc agaatgccca gct
//
