LOCUS       NZ_FWXV01000003        22583 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Kibdelosporangium aridum strain DSM 43828, whole genome shotgun
            sequence.
ACCESSION   NZ_FWXV01000003
VERSION     NZ_FWXV01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium aridum
  ORGANISM  Kibdelosporangium aridum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900176515.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:02:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,283
            CDSs (total)                      :: 11,193
            Genes (coding)                    :: 11,032
            CDSs (with protein)               :: 11,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 3, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 38 of 161
            Pseudo Genes (incomplete)         :: 135 of 161
            Pseudo Genes (internal stop)      :: 6 of 161
            Pseudo Genes (multiple problems)  :: 17 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:58:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 538101
            Orig. end                         :: 560684
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FWXV01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22583
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="8"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22583
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22583
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12583](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12583)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(669..685)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.69"
                     /tool="antismash"
     gene            complement(1040..3787)
                     /locus_tag="B9C43_RS21480"
                     /old_locus_tag="SAMN05661093_04378"
     CDS             complement(1040..3787)
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019607.5"
                     /locus_tag="B9C43_RS21480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04378"
                     /product="carbohydrate-binding protein"
                     /protein_id="WP_200825632.1"
                     /transl_table=11
                     /translation="MANAGSVIPPGDYQQVQLALGPNELGEAMSLAILPNRSVVHTARD
                     GTVRVTDAAGNTSTAGKLDVYSHDEEGLQGVAADPNFASNRFIYLYYSPKLATPSGDAP
                     TEGTQADWDRWKGELHLSRFVLTTANTLDMASEKVVLRVANDRGQCCHTGGDIDFDTAG
                     NLYLTTGDDTNPFQSDSYTPIDERTNRNPQFDAQRSSGNTNDLRGKVLRIKPQPDGTYT
                     IPSGNLFAPGTPNTRPEIYAMGFRNPFRMNVDKATGIVYLGDYGPDAGSTNPNRGPNGQ
                     VEFNRITGPGNYGWPYCTGTNTPEETYNDYQFPSGPSGAKFNCAGGPTNNSFRNTGQQT
                     LPSAKPSWIKYGGDSGTPPEFGGGSESPMGGPVYRYDANLNSSIKFPQSLNGRYFAGEY
                     GRRWIKAIEVTSTGGVGDIGAFPWTGTQVMDMNFGPDGALYVLDYGTGSGNQALWRIEY
                     IGGQNRNPVAVASANRTSGPAPLAVNFSSAGSNDPEGGALTYSWNFGDGTTSTQANPSK
                     TYTANGKYTATLTVRDPQGLTGSANVQITVGNTAPSVSLQSPVDGQLFSFGDTVPFQVN
                     VSDPEDGTIDCSRVKVTYKLGHDSHRHDITSRNGCTGSIPVPIDGEHDPAANVYGVFDA
                     EYTDNGGLTTHDENILQPRHRQGEHFTSQNGGVQLAQHGAAEGGTTVGFTDNNDWVAFT
                     PYSLTGATSVTVRASSGGPGGTMEVRTGSATGPLLGSVQIPNTGSWDTFTNVSGNLSNV
                     PSGTTTLYLVFKGVTGQGNLFDIDAFTFNTSPSGGPSKTVEGEGYSSTSGVQPAPHANA
                     SGGHTAGYIENGDWAAYSTVDTSGAKAFEARVSSAGSGGTIQVRSGSPTGTLLGSVTVP
                     VTGGWENFQTVSANLSATASGTLYLVFTGGSGFLFDVDTVTVKF"
     misc_feature    complement(3170..3172)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3888..5348)
                     /locus_tag="B9C43_RS21485"
                     /old_locus_tag="SAMN05661093_04379"
     CDS             complement(3888..5348)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF027641.5"
                     /locus_tag="B9C43_RS21485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04379"
                     /product="discoidin domain-containing protein"
                     /protein_id="WP_084428662.1"
                     /transl_table=11
                     /translation="MRTLRSIVGLLVFLLTLGMVTAPPASASLAVQAVAADVHLFYYPW
                     YGNPSLNGNYRHWQQGGHTPPDDIGADFYPALGAYDSGDTAVIDQHMRWIQQSGAGTII
                     SSWWGQGSYEDRMAPAILASAARHGIKVAWHLEPYGTRTAESTVSDINYINAKYGSSPA
                     FYRYGNRGAFYVFESLRITDWSALEQVKSTSIVLAQTTDPARVAHFGGMYTYDGIAGAT
                     APGWKTASDFCKANGLVWAPSVAPGYIDDRGVPGNTTPTVHRDNGAMYDRQWSNALNPA
                     TGGAPTWVSVTSFNEWHEGSTIEPARSNPPAGHGYLTYQGAYGKTGSAAETSYLDRTKY
                     WVGQFTGGSIPPTNPNLAQGKPISASSTQNGYPAVNANDGNTNSYWESANHAFPQSLTL
                     DLGTATEVSKLVLSLPPSWGPRTQTLTVYGDGSAIVPAKGYTFDPASRNTVTITFPATA
                     QRTFRLHFTGNTGWPAGQIAELQAYRIP"
     misc_feature    complement(5443..5457)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.83"
                     /tool="antismash"
     misc_feature    complement(5453..5471)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.2"
                     /tool="antismash"
     gene            5775..>6356
                     /locus_tag="B9C43_RS21490"
                     /old_locus_tag="SAMN05661093_04380"
                     /pseudo=""
     CDS             5775..>6356
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="B9C43_RS21490"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04380"
                     /product="response regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSAGPQVSPETTGYPATASGLIRVLLVVDMDLLRDALVTLLSEQH
                     DMEVVADLKCDDNVIPIATRIRPDVAVIDVDQPCSRGLAMIPELRARLPRMQVVALAAA
                     SPPGLVQRALTAEVLGLVDKNASATRLIAAIRGAARGSQVVDVNLAVAALAAGPNPFTP
                     RELQVLRLAADGASGPEIASRLSLSKGTVRN"
     misc_feature    5895..5897
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6285..6287
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6285..8093)
                     /locus_tag="B9C43_RS21495"
                     /old_locus_tag="SAMN05661093_04381"
     CDS             complement(6285..8093)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075999.1"
                     /locus_tag="B9C43_RS21495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04381"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_084428663.1"
                     /transl_table=11
                     /translation="MKREVRFGVAALRAGPAFALLGWSIPEALPTAISGLAVANAVDDG
                     FLAGRPVVGFGWLAVLMVAAVIGSAGSRKVFQRLGELVEPFRDDLVRRVVGSALYKGVS
                     GQPDEGALARLTRQVEIVRDTYAGLIVVIRSFVVTVVGVVIGLLSLAPVVVLLILPPFL
                     LGFGAFLATLGFAAAKQRASVLADERLAASAGTVLAGTRDVVACGAEDHAAAMVSGPIH
                     DQAAAERAMAKVAALRTACFAVGGWLPLAAILIAGPWLVGQGLTAGLIMGGLTYVVSGL
                     QPALQAVIAGVGGSGLRFVVTLGRILDETTIPPVEGPREHDRQGEDLILRDVRFAYGPH
                     SEPILRDLDLTILPGEHLAVVGPSGIGKSTLASLICGLREPDAGSIRFGGIRAGDLDAA
                     DRVLIPQEAYVFAGPLRDNLTYLRPDATDAQIQDAVAAVGARDLVEKIGDQLDPSGLSA
                     GQRQLIALVRAYLSPARLMVLDEATCHLDPVAERRAEEAFARRGGTLIVVAHRISSARR
                     AERILVLDGVTAAVGDHASLVRRSPLYRDLWGHWSQPARLTHDPDGIDAGAGASLAHHL
                     GQVVPHGPLGQRQPGGDLRSGGTVGG"
     gene            complement(8090..9739)
                     /locus_tag="B9C43_RS21500"
                     /old_locus_tag="SAMN05661093_04382"
     CDS             complement(8090..9739)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076000.1"
                     /locus_tag="B9C43_RS21500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04382"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_084429130.1"
                     /transl_table=11
                     /translation="MTTFGAIARHGGRLLPVIGVSALVGTLSTLALPFVLGKAVDAIVT
                     GSPGSTWLVMAGLLIAVGIASDLVDSFAGVACVAGTTAWLRERLVRHLLAAGPDRGFDT
                     GDLVTRVSGNAVDAAQAGPAVVTVWMAVLPPAGSLVLLVVIDPWLAVAFLGGVALVALV
                     LRAFTRRTAQVITSYQQVQGRIAARLAESLAGARTIAAAGTLCEEKRRVLRELPTLHDQ
                     GMASWQVLARSVSHAGVVGPLVTVSVLAAGGVALLNGRITPGELFAALQYAVLGAGLGS
                     MTSVFSRLARAKAGANRAAEVLDVQPIGYGHLWLPEGKGRLEFRHITVYRGETAVLDDV
                     TLTLPGGKAIAVVGRSGAGKSTLAAVAARLTEPANGDVLLDDVPLKFLTHEDLRKAIGC
                     AFDRPVLVGGTVADAIGMGRAGDVRSAAKATHAHEFVSRLPRGYNTPLAEAPMSGGEAQ
                     RLGLARAWNAERLLVLDDATSSLDMVTEMQIGRTLTEDHGHRTRLIITHRVATAAKADL
                     VVWLDSGRVRAVGPHEVLWRDPAYQDVFGAAE"
     gene            complement(9824..9976)
                     /locus_tag="B9C43_RS55710"
                     /old_locus_tag="SAMN05661093_04383"
     CDS             complement(9824..9976)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007027060.1"
                     /locus_tag="B9C43_RS55710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04383"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_125727639.1"
                     /transl_table=11
                     /translation="MSVLDLQGMEAAPQTGGHGGGSSNSGHSCPSNLSVTLCGGTSGLS
                     LLICH"
     CDS_motif       complement(9917..9976)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSVLDLQGMEAAPQTGGHGG"
                     /locus_tag="B9C43_RS55710_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9824..9916)
                     /prepeptide="core"
                     /locus_tag="B9C43_RS55710_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="6.00"
                     /molecular_weight="2709.0"
                     /monoisotopic_mass="2707.3"
                     /core_sequence="GSSNSGHSCPSNLSVTLCGGTSGLSLLICH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSVLDLQGMEAAPQTGGHGG"
                     /leader_location="[9916:9976](-)"
                     /alternative_weights="2727.0"
                     /alternative_weights="2745.0"
                     /alternative_weights="2763.1"
                     /alternative_weights="2781.1"
                     /alternative_weights="2799.1"
                     /alternative_weights="2817.1"
                     /alternative_weights="2835.1"
     gene            complement(10001..12583)
                     /gene="lanKC"
                     /locus_tag="B9C43_RS21505"
                     /old_locus_tag="SAMN05661093_04384"
     CDS             complement(10001..12583)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="B9C43_RS21505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04384"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_084428664.1"
                     /sec_met_domain="micKC (E-value: 3.3e-249, bitscore: 825.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2.2e-14, bitscore: 49.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3e-08, bitscore: 28.7,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEEYEAYCMADPSFYDAMHSEQTAGESFAAAHRALPDGWTCYEQ
                     DDWFVLNPGTQNTPLQGWKIHASATPDNASRVIDKVFDYCVPRGIQFKFLRSRSALTAR
                     VSKYAPRGFSGKLVTIYPQDDGQCERILTELGEILEGEPSPYILSDLRWGKGPLYVRYG
                     AFANRYTVDETGEVVDAIAAPDGTLVADRRGPVFYTPPWVTLPSFLEPHLAARNAVTVT
                     DLPYTFDSVVHFSNGGGIYVGKDTRTGKEVVLKEARPHAGLDAWAHDAVRRLEREHNTL
                     RRLAGIPGIPEVYDLFWLGEHRFMVMEYVKGDVLGKAITMRYPLIDPAATDEDHARFTD
                     WAVKIHRQVEQTMKAVHERGIVYGDLHLFNIIVREDDTIALLDYEVAAPVEEATRPGLG
                     NPGFTAPRSVTGFGVDEYAVACLRLALFLPMTNLLGLHRVKARQFADIIAEHFPVSREF
                     LEKGVDVIVPPDTPATPSPRITTDRAGWPKVRDDMVRAIVASATPDRDDRLFPGDPRQF
                     GVGGLGLAHGAAGVLYALSVTGGHRCEQFEDWLVRRATSPAGGSRIGLFDGLHGAAFTM
                     DHLGYRQQALDTLDICLREKWEAVGPDLMTGLSGIGLNLLHFADRTGEPALRMAALRAA
                     ELVAERPDDQDDSGISGGTHPHAGLFRGRAGQALLLLRAYDDTGDANFLDRAANALRQD
                     LKRCFLRDNGVLEINEGWRTMPYLDGGSVGLGIVLDEYLARKHDDQFVEANRGIENAAR
                     STMYILPGLFTGRAGILAYLAGRMPGTDPLVTKQIRNLAWHALPYGDGIAYPGTALLRL
                     SMDLATGTAGVLLAVGMALHDEPVHLPLLAPTRRAAPQTPAPTGAGSQ"
     gene            complement(12788..13960)
                     /locus_tag="B9C43_RS21510"
                     /old_locus_tag="SAMN05661093_04385"
     CDS             complement(12788..13960)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681242.1"
                     /locus_tag="B9C43_RS21510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04385"
                     /product="ABC transporter permease"
                     /protein_id="WP_033381373.1"
                     /transl_table=11
                     /translation="MRLRPRDAISLGLLGIRGRPLRTTLSCLGIAIGIACVVAVLGVSA
                     SSQAGLLKQIDQLGTNLLTVRPGNNAFGDTATLPPQAPAMIGRLPGVQQVAHVGRVPGA
                     VYRHDRMPEVSTGGISILAASPGLPETLQVPVVEGTWFNQAIDRYPTTVLGAATARRLG
                     VTAGHQVFLGGQWFTVIGVLGTALLDQTIDSAALVGYPAAQTLFGFDGAPTTVYERSAS
                     EAVEALVPQLATAANPADPGAVKVSRPSDVLVARSAVESAYNGLFLGLGGVALLVGTVG
                     IANVMVIGVLERRGEIGLRRALGASRRHIRVQFLVESVVLSHLGGIAGLAIGSAVTAGY
                     AAVREWDVVVPPAALLGGLAASIFAGTLAGIYPAARAARLSPTEALRAVG"
     gene            complement(13957..14607)
                     /locus_tag="B9C43_RS21515"
                     /old_locus_tag="SAMN05661093_04386"
     CDS             complement(13957..14607)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020420260.1"
                     /locus_tag="B9C43_RS21515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04386"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_084428665.1"
                     /transl_table=11
                     /translation="MTLELHKVTKKYGELTVLRDIDLIVRSGELVAVVGPSGSGKTTLL
                     QIMGTLDQPTAGTVRVAGQDITGMPDRRLAVVRAYHIGFVFQQFFLNPTLSAMDNVATG
                     LLYTGTPRQQRRERAAEALASVGMSHRMKHRPGQLSGGECQRVAIARAVVGRPDVVLAD
                     EPTGNLDSRSGAAVAGLLRRLNETGTTVVVITHDDRLAASMPRTVRIQDGVIQ"
     gene            complement(14604..15638)
                     /locus_tag="B9C43_RS21520"
                     /old_locus_tag="SAMN05661093_04387"
     CDS             complement(14604..15638)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013625.5"
                     /locus_tag="B9C43_RS21520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04387"
                     /product="peptidoglycan-binding protein"
                     /protein_id="WP_160096622.1"
                     /transl_table=11
                     /translation="MRGWIVATVLLATACTSQAQPQAEQKPLPTAPVTRGDLVSSIQQP
                     GQLGYVGSIQLVAQRQGTVTAMPGVGQVISRGQQVYAVDQRPIPLFYGTLPFYRPLNRA
                     VEGEDVRQLERNLVDLGHATFTPDDTYTSATVNAVKRWQKSLGLTETGTVEPGDALVAA
                     GPVRVTATNGLVGAMARPGEALVTGTGTEHGVHVDLDRRHRSMAAVDQTVQVRLFGGRS
                     VTGVVKTIESTATQPQQNGQQNTNQERQTIGVDILITSPEAELGGVFEGPVTVIFPGES
                     RRGVLTVPIEALTVVPGGAYAVVVVDQNGRHTIEVEPGLFTASRVEITSPGLVEGMRVE
                     VPTI"
     gene            complement(15635..16144)
                     /locus_tag="B9C43_RS56775"
                     /old_locus_tag="SAMN05661093_04388"
     CDS             complement(15635..16144)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9C43_RS56775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05661093_04388"
                     /product="hypothetical protein"
                     /protein_id="WP_160096625.1"
                     /transl_table=11
                     /translation="MRKAMLIIAAVVMAGCQATTEPVKPAKSEEISRTAVGFSQCMRDR
                     GHQVPDPAFNEDGLPVFQEPEDERRTQGYQTDRQQCRQPLNDAMVAAGVPNQKGTPEQW
                     LAFARCMREHGVDMPDPTPDNRFTIEKNLYDSPAWQPAFEACDEHLPPQMREALDSPPG
                     KGGNGK"
     gene            16233..16883
                     /locus_tag="B9C43_RS21530"
                     /old_locus_tag="SAMN05661093_04389"
     CDS             16233..16883
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670900.1"
                     /locus_tag="B9C43_RS21530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04389"
                     /product="response regulator transcription factor"
                     /protein_id="WP_033381377.1"
                     /transl_table=11
                     /translation="MRVLVVEDDAVLAEAIARGLRRHAMSVDVAVDGARALECAAVTRY
                     DVVVLDRDLPGVHGDEVCRQLTGDSTRILMLTAASTVRDRVSGLNLGADDYLPKPFAFD
                     ELVARVHALLRRSAPARAPVVSRAGITLDPAQRVVFRDGRFIRLSPKEFAVLYVLLSAD
                     GAVVSAEELLDRAWDEHADPFTNSMRTTVGTLRKKLGEPPVIGTVVGAGYQIR"
     gene            16880..17947
                     /locus_tag="B9C43_RS21535"
                     /old_locus_tag="SAMN05661093_04390"
     CDS             16880..17947
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="B9C43_RS21535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04390"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_084428668.1"
                     /transl_table=11
                     /translation="MRLTARTRLTLLFSALIAFSGAVLAVIVIVLAFTPNRANAEPKIP
                     ANKVVVMEKSQIDQLGVDIKAQARTELLDRLMLGAGIGIGVLTVGSAGLGWLLAGRVLR
                     PVHVVSGTARRLSQQNLHERIPVSGPQDEMRELAETFNDMLARLQRSFDAQSHFAANAA
                     HELRGPMTTQRTLVEVAACAPDAPPPLRELASSLGPVLDRQERLVNGLLELAWSEHGVT
                     KVEPVRVDSLVRAPGASLSLQPLTVRGDPTLLDLMVDNLVRNAFTHGREVWVSTTSDSL
                     CVENTGEVVPAERLATLTEPFRRGSQDRLNSNGTGLGLAIVNAVVRAHNASLELTPRPG
                     GGIRATVRFPAGTMR"
     gene            17948..18316
                     /locus_tag="B9C43_RS21540"
                     /old_locus_tag="SAMN05661093_04391"
     CDS             17948..18316
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337385.1"
                     /locus_tag="B9C43_RS21540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04391"
                     /product="VOC family protein"
                     /protein_id="WP_084428669.1"
                     /transl_table=11
                     /translation="MARLRDIVIDCKHPASLARFWAAVLDDYEIAPYDDEELARLRSIG
                     VESPEDDPTVLLQRLDGAPPRIFLVLVPEPKTVKNRVHLDIDGDVNAVLALGATLVAKH
                     EGHHLLNDPEGNEFCVIP"
     misc_feature    17961..17973
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     gene            18313..19185
                     /locus_tag="B9C43_RS21545"
                     /old_locus_tag="SAMN05661093_04392"
     CDS             18313..19185
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099653.1"
                     /locus_tag="B9C43_RS21545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04392"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_084428670.1"
                     /transl_table=11
                     /translation="MIHEHPLAYVLGLQGIALLQGFIGEHDRDFIEARLAEIRELLDNE
                     QLTQAVEVTPVSTVDGYRTWSATYDSPSNPVFEMDVPILKEILADVPAGMALDAACGTG
                     RYAELLAGQGHRVIGVDSSPDMLERARKRLPDSEFREGTLHHLPVDEVDLILCGLALTH
                     NPDLGPIFAEFARVLRPGGHLVVVDMHPDAILRGSIPTVRGPKGEPCRVVTYRHSMGDY
                     LRASLSNGLTVRRCEELRSASMLEKTDSPGPWDVWPWSLAALAPEAAYAATGPQMVIWH
                     FQADILHTM"
     gene            19206..19670
                     /locus_tag="B9C43_RS21550"
                     /old_locus_tag="SAMN05661093_04393"
     CDS             19206..19670
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944927.1"
                     /locus_tag="B9C43_RS21550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04393"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_033381381.1"
                     /transl_table=11
                     /translation="MTEPDARNLLLLDEQACFALYAASRAVTDVYRPLLAELDLTYPQY
                     LVMLVLWERDNQPIKQIGAALHLDYGTVSPLLKRLEARGLVQRKRQADDERSVVVSLTP
                     EGVAMRERAVAIPPAIGCALGLNNQDLGVLMDLLRRVTTSARTTAQEGEH"
     gene            19673..20110
                     /locus_tag="B9C43_RS21555"
                     /old_locus_tag="SAMN05661093_04394"
     CDS             19673..20110
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020660637.1"
                     /locus_tag="B9C43_RS21555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04394"
                     /product="OsmC family peroxiredoxin"
                     /protein_id="WP_033381382.1"
                     /transl_table=11
                     /translation="MPSRDATTHWEGDLQTGGGNVTLDSSNAGQFRVTFPARTGDPEGM
                     TSPEELIAAAHSSCLAMNFTGTVKKAGFTPGTVDVSAEVTLGPDPEGGFKLTEIAVTLV
                     AKVDGLDKDKFAELAATAEKTCPISKALAGTTITLDASLAE"
     gene            20137..21558
                     /locus_tag="B9C43_RS21560"
                     /old_locus_tag="SAMN05661093_04395"
     CDS             20137..21558
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020636010.1"
                     /locus_tag="B9C43_RS21560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04395"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_084428671.1"
                     /transl_table=11
                     /translation="MTVSRRDLLVGLGAAMTGFGMAAPPDWDRLRRRLAGPLYLPQDAG
                     YAAARQGYFTIHDGQRPAAVARCTRIEDVQACVEFAAATRTPVSARSGGHSYAGYSTRD
                     GSLVVDLRQLAGIQLYPDGTAVIGAGAQLIDVYATLAQAGRLLPGGTCPSVGIAGLTLG
                     GGIGVTARKYGLTCDRLVSAQIVTADSRLRTVSAVQEPELFWALRGGGGGNFGIVTSFT
                     FQTAPATDLTVFALEFPAAALPALLGGWQSWPVPDEVWSNVSVPGDPQATTWVDGCFVG
                     SSSGVQPHLDKLTRLVGTQPLARIVKQFSYFDAMRYFAGCSELSLKECRPNWTSDAGLL
                     DRGAYVATSRMIGAPLRDPAATAALLRSSPGLTTQFDSFGGEIARGPDTAFPYRQSIAS
                     MQVTHEFDGTARQAIAHVRDETAREFGQTGYINYIDPHMPNWAQAYYGSNLAKLRTIAR
                     RYDPGRVFAFAQGLS"
     gene            21592..21990
                     /locus_tag="B9C43_RS21565"
                     /old_locus_tag="SAMN05661093_04396"
     CDS             21592..21990
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154308.1"
                     /locus_tag="B9C43_RS21565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04396"
                     /product="SgcJ/EcaC family oxidoreductase"
                     /protein_id="WP_084428672.1"
                     /transl_table=11
                     /translation="MDTEIAAIKQVIATVEHSQQNELPDEFVSLFRADAIWTTGHGKRL
                     TGRDEISTFTHKVLPGAMRDSTCAYEVVDILFIRPDVAAVKARARYLTLDGQQIGNEGT
                     PLYVMSKENGEWKLVACQNTEVLDFEST"
ORIGIN
        1 gcgtggacgt cgcgggtgcc aacagcgcca acggaaccgc cgtccagctg tacgactgca
       61 acggcaccaa tgcccagcag tggaacaaca cgggctcagt gctgcaggcg ctcggcaagt
      121 gtcttgacgt cgccggtggc ggcaccgcca acgggaccgt cgtccagttg tgggactgca
      181 acggcagtgg cgcgcaaagc tgggttgtca gcggcgccaa cgacatcgtc aacacccagg
      241 ccaacaagtg ccttgacgtc actggcaaca actccgccaa cggcacccgg ctgcagatct
      301 gggagtgcac cggcggtccc aaccagaagt ggaacgcacc tgccggtggt ggcggcaacc
      361 ctggcggctt cgtcgtcacc gaggcccagt tcaaccagat gttccccggc cgcaacggct
      421 tctacaccta cagcggactg gtcgccgcgc tgagctcgta cccggccttc gccgggaccg
      481 gcagcgacgt gacccgcaag caggaagccg cggcgttcct ggccaacgtc tcccacgaga
      541 ccggcggtct ggtgcacgtc gtcgagcaga accaggccaa ctacccgcac tactgcgact
      601 ggggccagcc ctacggctgc ccggccggac aggccgcgta ctacggccgc ggcccgatcc
      661 agctgagctg gaacttcaac tacaaggccg cgggcgacgc gttgggcctg ccgctgctga
      721 acaacccgtg gctggtgcag aacgacgcgg ccgtcgcgtg gcgtaccggc atctggtact
      781 ggatgaccca gaacggccca ggaaccatga ccccgcacaa cgcgatggtc aacggccgcg
      841 gtttcggtga gacgatccgc agcatcaacg gttcgctgga atgcaacggc ggcaacccca
      901 gccaggtcca gagccgcgtg aacaactaca accgcttcgt cggcatcctt ggcgtgcccc
      961 caggcggcaa cctctactgc tgattcatga ccaggaagcg gcactcacct cgcccaggtg
     1021 agtgccgctt cgtgcgttcc tagaacttca ccgtcactgt gtccacatcg aacaggaagc
     1081 cggagcctcc ggtgaacacg aggtagagcg tcccggacgc ggttgcgctc agattcgccg
     1141 acacggtctg gaagttctcc cagccgcccg tgaccgggac cgtgacggat cccaacaacg
     1201 ttccggtcgg cgaaccagac cggacctgga tcgtgccacc cgaacccgcc gaggacacgc
     1261 gagcctcgaa ggccttggcg ccagacgtat ccacagtgga atacgcggcc cagtcaccgt
     1321 tctcgatgta accggccgtg tgtccgccgc tggcattggc atgcggggcg ggttggacgc
     1381 ccgaggtcga cgaatacccc tcaccctcga ccgtcttcga cggcccaccg ctcggtgagg
     1441 tgttgaaggt gaacgcgtcg atgtcgaaca ggttcccctg gcccgtgact cccttgaaca
     1501 ccaggtacaa ggtggtcgtt ccggatggga cattgctcag gttgcccgac acgttggtga
     1561 acgtgtccca gctgcctgtg ttggggatct ggactgaacc aagcaaaggt ccggttgccg
     1621 agccggtgcg gacctccatc gtgccgccgg ggccgccgga ggaagcgcgg acggtgacac
     1681 tggtcgcacc ggtcagcgag tacggcgtga aggcgaccca gtcgttgttg tcggtgaacc
     1741 cgacggtcgt gccaccttcg gccgcgccgt gctgagcgag ctgcacacca ccgttctggc
     1801 tggtgaagtg ctcgccctgt cgatgccgtg gctgcaggat gttctcgtcg tgcgtggtca
     1861 agccgccgtt gtcggtgtac tccgcgtcga acacgccgta gacgttcgcg gctgggtcgt
     1921 gttcgccgtc gatcggcacc gggatcgacc cggtacagcc atttctggat gtgatgtcat
     1981 gccggtggct gtcgtggcca agcttgtacg tcaccttgac ccggctgcag tcgatcgtgc
     2041 cgtcctccgg gtccgacacg ttcacctgga acggcactgt gtcaccgaag gagaacagct
     2101 ggccgtccac aggagactga aggctcaccg atggcgcggt gttgcccacg gtgatctgca
     2161 cgttcgccga accggtcaag ccttgtggat cacggacggt caacgtggcc gtgtactttc
     2221 cgttggctgt gtatgtcttc gacgggttgg cctgcgtcga agtcgtgccg tcgccgaagt
     2281 tccacgagta cgtcaaggcc ccgccttcgg ggtcattgct tcccgcggat gagaagttga
     2341 ccgccagcgg ggccgggcca gaggttcggt tggccgaggc gaccgcgacg gggttgcggt
     2401 tctggccacc gatgtactcg atccgccaga gcgcttggtt gccggatccg gtcccgtagt
     2461 ccaggacgta cagtgcgccg tccggaccga agttcatgtc catgacctgc gtaccggtcc
     2521 acgggaacgc gccgatgtca ccgacacctc cggtggaggt gacttcgatc gccttgatcc
     2581 agcggcgacc gtactcaccc gcgaagtacc ggccgttcaa cgactgcggg aacttgatcg
     2641 acgagttgag gttggcgtcg taccggtaga ccgggccgcc catcggcgac tccgaaccac
     2701 cgccgaactc cggtggtgtg ccgctgtcgc cgccgtactt gatccacgaa ggcttggcgg
     2761 acggcagggt ctgctgtccg gtgttgcgga acgagttgtt cgtcgggccg cccgcgcagt
     2821 tgaacttcgc accggaaggt ccactaggga actggtagtc gttgtacgtc tcctccggcg
     2881 tgttcgtccc ggtgcagtag ggccagccgt agttgcctgg gccggtgatc cggttgaact
     2941 cgacctggcc gttggggccg cggttggggt tcgtagaccc ggcgtccggt ccgtagtcgc
     3001 cgaggtacac gatcccggtc gccttgtcga cgttcatccg gaacgggttg cggaaaccca
     3061 tcgcgtagat ctcaggccgg gtgttgggtg tgccgggagc gaacaagttc ccggacggga
     3121 tggtgtacgt gccgtcaggc tgcggcttga tccgcagcac cttgccgcgt aagtcattgg
     3181 tgttgccgga cgagcgctgg gcgtcgaact gcgggttgcg gttggtgcgc tcgtcaattg
     3241 gcgtgtagct gtcggactgg aacgggttgg tgtcgtcacc cgttgtcaga tacaggtttc
     3301 cggcggtgtc gaagtcgatg tcaccgccgg tgtgacagca ctggccgcgg tcgttcgcca
     3361 cccggagcac gaccttctcg ctggccatgt ccagggtgtt ggcagtggtc aggacgaacc
     3421 gggacaggtg gagctcgccc ttccacctgt cccagtccgc ctgtgtcccc tcggtcggcg
     3481 catcgccgct cggtgtggcc aatttgggtg agtagtagag gtagatgaac ctgttgctcg
     3541 cgaagttggg gtcggccgcg accccttgca ggccttcctc gtcgtgggaa tacacgtcga
     3601 gcttgcccgc agtgctcgtg ttgcctgccg cgtcggtgac acggactgtg ccgtcacgag
     3661 cggtgtgcac cacggatctg ttcggcagga tcgcgagcga catcgcctcg ccgagttcgt
     3721 tcggcccgag cgccagctgc acctgctggt agtcgcccgg cgggatgacc gatcctgcgt
     3781 ttgccacggg ggtggggatg ctgacggcgg cggtgaccat tagtgcggcc gtgaagccac
     3841 accgacgccg cccgggggac ggggccatcg gtgtcctttc tggactttta cgggatgcgg
     3901 tacgcctgca gctcggcgat ctgcccggcg ggccagccgg tgttgccggt gaagtgcagg
     3961 cggaacgtcc gctgggccgt ggcggggaag gtgatcgtca cggtgttgcg tgacgcggga
     4021 tcgaaggtgt agcccttcgc ggggacaatc gccgaaccgt cgccgtacac cgtcagggtt
     4081 tgcgttcggg gaccccatga cggtggcagg gacagcacaa gcttgctcac ctcggtggca
     4141 gtgccgaggt cgagcgtgag cgactggggg aaggcgtgat tcgcgctttc ccagtagctg
     4201 ttggtattcc cgtcgttcgc gttgaccgct ggatacccgt tctgagtgct gctggcggat
     4261 atcggtttgc cctgtgccag attcgggttc gtgggcggaa tgctcccgcc ggtgaactgg
     4321 ccgacccagt acttggtgcg gtcgaggtac gacgtctccg cagcggaccc ggtcttgccg
     4381 tatgcgcctt ggtacgtcag atagccgtgt cccgcgggcg ggttcgaccg ggcaggttcg
     4441 atggtcgagc cctcgtgcca ttcattgaac gacgtcaccg agacccatgt cggcgcgcca
     4501 ccggtggccg ggttgagcgc attgctccac tgcctgtcgt acatcgcgcc gttgtcacgg
     4561 tggaccgtcg gtgtcgtgtt gcccggcacc ccacggtcgt cgatgtagcc aggcgcgacc
     4621 gaaggcgccc acaccaaacc gttggccttg cagaagtccg acgcggtctt ccagccgggc
     4681 gcggtcgcac cggcgatgcc gtcgtaggtg tacatcccgc cgaagtgggc gaccctggcc
     4741 gggtcggtgg tctgcgccag cacgatgctg gtcgacttga cctgctccaa cgcgctccag
     4801 tcggtgatcc gcagactttc gaagacgtag aacgcgccac ggttgccgta ccggtagaac
     4861 gccgggctgc tgccgtactt ggcgttgatg tagttgatgt ccgagactgt ggactcggcg
     4921 gttctggtgc cgtacggctc aaggtgccag gcgaccttga tgccatgccg cgcggcggag
     4981 gcgaggatgg cgggcgccat tctgtcctca tatgaccctt gcccccacca gctcgagatg
     5041 atcgtgcccg cgccggactg ctggatccag cgcatgtgtt gatcgatcac cgcggtgtcg
     5101 ccggagtcgt aggcacctag cgccgggtag aaatcggcac cgatgtcatc gggtggagtg
     5161 tggccgcctt gctgccaatg ccggtaattc ccgttcagtg acgggtttcc ataccacggg
     5221 tagtagaaga gatgaacgtc agccgcaacc gcctgcaccg ccaaggaggc cgacgccggc
     5281 ggcgccgtga ccatgccgag ggtgagcagg aagaccagca ggccgacaat gcttcgcagg
     5341 gttcgcatgt ctgtctgctc tcaatcctct ggcgccattg ccagatgacc gggataataa
     5401 gttcagcgcc tctactaaag caagatataa actacataac gcaaatttct gacttatact
     5461 ggacacggct tcaccattcg ctaaacccgc gacggactcc gtgggcgcga cgcacagcga
     5521 gaacggacaa cgtccttccg agtcagagat agccacggct tgaccgttct tttgtcacgt
     5581 ccggcctagc gacgtccccc aggaccgctg ccacctcgac gaatcccgga attcaccggt
     5641 tgattatttg ccggattgct ccattggtat gagccaagat ccaacgcaaa ggcgcgcagg
     5701 taacggccat atgcccaacc cgtatctagg gatcgcgtgg ggagctcgcc cagggctctg
     5761 gagagggagg acgaatgtcg gcagggccgc aagtcagccc cgagacaacc gggtacccgg
     5821 ccaccgcgtc ggggttgatt cgagtgctgc tggtcgtgga catggatcta ctgcgcgacg
     5881 cactcgtgac actgttatcc gaacaacacg acatggaggt ggtcgccgat ctgaagtgcg
     5941 atgacaacgt tatcccgata gcgacgagga ttcggcccga tgtcgcggtg atcgatgtgg
     6001 accagccgtg ctcccgtggc ctggcaatga tcccggagct gcgtgcccgg ctgccgcgca
     6061 tgcaggtcgt cgcattggcc gcggccagcc ctcctggtct ggtccaacgg gcgctcaccg
     6121 ccgaggtgct ggggcttgtc gacaagaacg cgtcggccac ccggttgatc gccgcgatcc
     6181 gtggtgccgc acgaggttcg caggtggtgg acgtcaatct ggctgtcgcc gcgctggcgg
     6241 cgggaccgaa cccgttcacg ccgcgggaac tgcaggtact tcgattagcc gccgacggtg
     6301 cctccggacc ggagatcgcc tcccggctgt cgctgtccaa ggggaccgtg cggaactact
     6361 tgtccaaggt gatgagcaag acttgcgccc gcacccgcat cgatgccatc cggatcgtgc
     6421 gtgaggcggg ctggttgtga ccaatgcccc cagaggtctc ggtacaacgg tgaccgccgt
     6481 acgagcgaag cgtggtcgcc gaccgcggct gtgaccccgt ccaatacgag gatccgctcg
     6541 gctcgccgcg ctgagctgat ccggtgcgcc accacgatga gcgttccacc tcgccgtgcg
     6601 aatgcttcct cggcgcgccg ttcggccacc gggtcaaggt gacacgtggc ctcgtcgagc
     6661 accatgagcc gggccgggct cagataagcc cggaccaacg cgatcagctg ccgctgcccc
     6721 gcggacagac ccgacgggtc gagctggtcg ccgatcttct cgaccaggtc acgtgcaccg
     6781 acggcggcga ccgcgtcctg gatctgggcg tcggtcgcgt ccggccgcag atacgtcagg
     6841 ttgtcccgca acgggcctgc gaagacgtag gcctcttggg ggatcagcac ccggtccgcc
     6901 gcgtccaggt cgcccgctcg tatcccgccg aaccggatcg agcccgcgtc cggttcacgc
     6961 aggccgcaga tcaggctggc caatgtggac ttcccgatcc cgctcgggcc gaccaccgcg
     7021 aggtgttctc ccggcagaat ggtcagatcg aggtcacgca ggatcggctc ggagtgcggg
     7081 ccgtaagcga accggacatc acgcaggatc aagtcctcgc cttggcggtc atgctcgcgt
     7141 ggcccctcga ccggcgggat cgtcgtctcg tccaggatcc ggccgagcgt caccacgaac
     7201 cgcaggccgc tgccaccgac tccggcgatg acggcttgca gggccggttg caggccggag
     7261 accacgtacg tcaggccgcc catgatcaga cccgcggtca gtccttgtcc aaccagccaa
     7321 ggcccggcga tcaggatggc ggccaacgga agccaaccac cgacggcgaa acacgcggtg
     7381 cgcagggcgg cgactttggc catcgcgcgt tcggcggcgg cctggtcgtg gatcgggccg
     7441 gacaccatcg cggcagcgtg atcttcggcg ccgcatgcga ccacgtcccg cgttccggcc
     7501 agcacagtgc ccgcgctcgc ggcgagtctc tcgtcggcca gaaccgaagc tctttgcttg
     7561 gccgccgcga acccgagtgt ggcgagaaag gcaccaaaac cgagcaggaa cggtggcagg
     7621 atcagcaaca ccacgaccgg cgcgagcgac aacaggccga tgaccacgcc gacaacggtg
     7681 accacaaagc tccggatcac gacgatcagt ccggcatacg tgtcccggac gatctcgact
     7741 tgccgagtca gccgggccaa cgcgccttcg tctggttgcc cggacacacc tttgtacaac
     7801 gcgctgccga caacccggcg gacgaggtcg tcacggaagg gctcgaccag ctcgccgagg
     7861 cgctggaaca ccttgcgtga tccggccgag ccgatcaccg cggccaccat cagcacagcc
     7921 agccagccga acccgacgac gggccgaccg gccaggaatc cgtcatcgac ggcattggcc
     7981 accgcgagcc cggatatcgc ggtgggcaag gcttccggta tcgaccagcc gagcaaggcg
     8041 aaagcgggcc cggctcgcag cgcggcgaca ccgaaccgga cctcgcgctt cactcggccg
     8101 ctccgaagac gtcctgatac gccggatctc gccacagcac ttcgtgcggt ccgaccgcac
     8161 gcacccgccc ggagtccagc cacaccacaa ggtccgcttt cgcggccgtg gcgactcggt
     8221 gcgtgatgat caaccgcgtg cggtggccgt ggtcctcggt cagcgtccgg ccgatctgca
     8281 tctcggtcac catgtccaaa ctggacgtcg cgtcgtcgag aacgagcagc cgctcggcgt
     8341 tccacgcgcg ggcaaggcca aggcgctggg cttcaccgcc ggacatcggc gcttcagcca
     8401 gcggtgtgtt gtagccccgc ggcagccggc tcacgaactc gtgcgcgtgc gtggccttcg
     8461 cagccgatcg gacgtcgcct gcacgaccca taccgatcgc gtccgcgacg gttcctccta
     8521 ccaatacggg gcggtcgaac gcgcagccga tggctttgcg cagatcctca tgcgtcagga
     8581 acttcaaggg gacgtcgtcg agaagcacat caccgttcgc tggttcggtg agccgggccg
     8641 cgaccgccgc cagagtcgac tttcctgcgc cggaccggcc gaccaccgcg atcgccttgc
     8701 cacctggcaa cgtcagcgtg acatcgtcga gaaccgctgt ctctcccctg tagacggtga
     8761 tgtgccggaa ctccagccgt cctttgcctt ccgggagcca gagatgtccg tagccgatcg
     8821 gctggacgtc gagaacctcg gccgcgcggt tggcaccggc cttggctctg gccagacggc
     8881 tgaagacact cgtcatgctg ccgagcccgg cgccaaggac cgcgtactgc aatgcggcga
     8941 acaactcgcc gggagtgatc cgtccattca ggagtgccac gccgccggcg gcgagcaccg
     9001 acactgtcac cagtggaccg accacaccgg cgtgcgacac agagcgagcg agcacttgcc
     9061 agctggccat tccctggtcg tgcaaagtag gcagctcacg caacacgcgg cgtttctctt
     9121 cgcacaacgt gcccgctgcc gcgatcgtgc gggcaccggc cagcgattcc gccagccggg
     9181 ccgcgattct tccttgcact tgctggtatg acgtgatgac ttgggcggtt cggcgggtga
     9241 aagcccgcag taccaaggcg acgagcgcga caccgccgag aaacgcgacc gcgagccacg
     9301 gatcgatcac cacgagcagg acaaggctgc cggcaggtgg cagcaccgcc atccacacag
     9361 tgaccacggc cgggcccgct tgtgcggcgt ccacggcgtt cccggacacc cgggtgacca
     9421 gatccccggt gtcgaaacca cgatccgggc cggccgcgag caggtgccgg accaagcgct
     9481 cgcgcaacca tgcggtcgtg ccggcgacgc aagctacgcc agcgaaggaa tccaccaggt
     9541 ccgaggcgat gcccaccgcg atcaacagcc ccgccatcac aagccaggtg gagccgggac
     9601 tgccagtaac gattgcgtca accgctttgc caaggacaaa gggcaaggcg agcgtgctca
     9661 atgtaccgac cagcgcggat actccgatca ccggaagcag gcggcctccg tgccgtgcga
     9721 tcgcgccgaa cgtcgtcacc acgggctcct atagttgggg cgcgaccccg gggcgagcga
     9781 cagtcgtccc ggggtcgcgc tgctctaacg atctacgact gtgtcagtgg cagatcaaca
     9841 gcgacaggcc ggaggtgccg ccgcacaggg tgacgctcag gttgctcggg cagctgtggc
     9901 cgctgttcga gctgccaccg ccgtggccgc cggtctgcgg cgcggcttcc atgccctgca
     9961 ggtcaagaac agacatctcg tctactcctt gtgtcggggg ttactgcgaa cccgcaccgg
    10021 ttggcgcggg cgtctgtggg gccgcgcggc gcgtgggcgc cagcaacggc aggtggaccg
    10081 gctcgtcatg cagagccatt cccaccgcga gcagcacacc ggcggtgccg gtggccaggt
    10141 ccatcgaaag tctcagcaaa gccgttccgg ggtaggcgat tccgtccccg tacggcaggg
    10201 cgtgccaagc cagattacgg atctgcttgg tgaccaaggg gtccgtgcca ggcatgcgac
    10261 cggcgagata ggcgaggatc ccggcgcgcc cggtgaacag tccaggcagg atgtacattg
    10321 tggatctcgc cgcgttctcg atgccgcggt tggcttcgac gaactggtcg tcatgcttgc
    10381 gagccaagta ctcgtcgaga acaataccaa ggccgacact gccgccgtca aggtacggca
    10441 tggtccgcca gccctcgttg atctccagaa caccgttgtc ccgcaagaaa cagcgcttca
    10501 ggtcctggcg caacgcgttg gcggcccggt caaggaagtt cgcgtcaccc gtgtcgtcat
    10561 aggcacgcaa caacaacagc gcttggccgg cacgcccacg gaacagcccg gcgtgcggat
    10621 gtgttccgcc gctgatgccg gagtcgtcct ggtcgtcagg gcgctccgcg accagctccg
    10681 cggcccgcag agcggccatc cgcagcgccg gttcgcctgt gcggtcagcg aagtgcaaca
    10741 ggttcagccc gatgccggac agcccggtca tcaggtcggg accgaccgct tcccacttct
    10801 cgcgaaggca gatgtccagt gtgtccagtg cctgctggcg gtaaccgaga tggtccatgg
    10861 tgaacgcggc gccatgcagt ccgtcgaaca ggccgatccg tgacccgccc gcagggctcg
    10921 tcgcccggcg cacaagccag tcctcgaact gttcgcagcg gtggccaccg gtgaccgaca
    10981 gggcatagag gacaccggcg gcaccgtgtg cgaggccgag accgcccacg ccgaactgcc
    11041 tggggtcgcc cggaaacaac cggtcgtcac ggtccggcgt ggcactcgcg acgatcgcgc
    11101 ggaccatgtc gtcacgcacc ttcggccacc cggcccggtc ggtggtgatg cgcgggctcg
    11161 gggtcgccgg ggtgtccggc gggacgatca catcgacgcc cttttccagg aactcccgcg
    11221 acactgggaa gtgctcggcg atgatgtcgg cgaactggcg tgccttcacc cggtgcagcc
    11281 caagcaggtt cgtcatcggc aggaacagcg cgagccgcaa gcacgccacc gcgtactcgt
    11341 cgacgccgaa cccggtgacc gagcgcggtg cggtgaagcc cggattgcca aggcccggcc
    11401 gggtcgcctc ttccaccggc gctgccactt cgtagtcaag caaggcgatt gtgtcgtcct
    11461 cgcgaacgat gatgttgaac aggtgcaggt cgccgtagac gatcccgcgc tcgtgcaccg
    11521 ccttcatggt ctgttcgacc tgccggtgga tcttcacggc ccagtcggtg aaccgggcgt
    11581 ggtcctcgtc ggtcgcggcc gggtcgatca gcgggtaccg catggtgatc gctttgccga
    11641 gcacgtcacc cttgacgtac tccatcacca tgaaccggtg ctcccccagc caaaacaggt
    11701 cgtaaacctc aggaatgcca gggatcccag cgagcctgcg cagggtgttg tgctcacgtt
    11761 ccagtctgcg cacggcgtcg tgcgcccagg cgtccagccc cgcgtgcggg cgagcctcct
    11821 tgagcacgac ctctttgccg gtccgcgtgt ccttgccgac gtaaatgccg ccgccgttgg
    11881 agaagtgcac gacactgtcg aatgtgtacg gcaggtcggt caccgtgacc gcgttgcgag
    11941 cagccaagtg cggttcgagg aagctgggca acgtgaccca cggcggggtg tagaagaccg
    12001 ggccgcgccg atcggccaca agcgttccgt ccggcgcggc gatcgcgtcg accacttcgc
    12061 cagtctcgtc cactgtgtac cgattggcga acgcgccgta ccggacgtac agcggcccct
    12121 taccccagcg caggtcgctg aggatgtacg gactcggctc gccttccagg atctcgccga
    12181 gctcggtcag tatccgctcg cattggccgt cgtcctgcgg gtagatggtg acgagcttgc
    12241 cgctgaaacc tcgcggagcg tatttggaaa cccgggcggt caatgcggag cgtgaccgga
    12301 ggaacttgaa ctggataccg cgcggcacgc agtagtcgaa gaccttgtcg atcacgcggc
    12361 tggcgttgtc cggcgtcgcc gacgcgtgaa tcttccagcc ttgcagcgga gtgttctggg
    12421 tgccggggtt gagtacgaac cagtcgtcct gctcgtagca agtccatccg tccggcaatg
    12481 cgcggtgtgc cgccgcgaat gactcgccgg ccgtctgctc ggagtgcatc gcgtcgtaaa
    12541 acgacggatc cgccatgcag taggcctcgt actcctcgtt catggctgca atcgttgtta
    12601 cctgttggct ggacgcatag tgagttccgt catcaggcga ctacgcgcct gtcaccagct
    12661 gacggtgcgt ttttcacatc cgccggttcc ggggcgtaac gctccgatca tccagtgcga
    12721 tgccccattt gacgaacggg ctggtcacca aagccccccg tggtgcccac cccgtttgtc
    12781 agtgacatca gcccactgcg cgcagagctt cagtgggtga aagtctcgcg gcacgcgcgg
    12841 ccgggtatat cccggccagc gtgccggcga aaatactcgc tgccagcccg cccaacaatg
    12901 ccgcaggcgg gacgaccaca tcccattccc gcacagcggc atacccggcg gtcacggctg
    12961 agccgatggc aagcccggcg attccgccaa ggtgggaaag aaccaccgat tcgacaagaa
    13021 attgcacgcg gatgtggcga cggctcgcgc cgagtgcacg gcgcaggccg atctcgccgc
    13081 gtcgctccag cactccgatc accatgacgt tggcgatccc gaccgtgccg accagcaggg
    13141 ccaccccgcc cagtccgagg aacaggccgt tgtacgcgct ttccaccgca ctgcgggcga
    13201 caaggacgtc cgacgggcgg ctgactttca ccgcacccgg gtccgccgga ttggctgctg
    13261 tggccagttg cggcaccagc gcttcgacgg cttcgctggc cgagcgctcg taaacagtgg
    13321 tcggcgcacc gtcgaaaccg aacaaggtct gagcggcggg atagccgacc agcgctgcgg
    13381 aatcaatggt ctggtccagt agggcggtgc cgagaacccc gatcacggtg aaccactggc
    13441 cgccgaggaa cacctggtgc cctgcggtga cgccgagcct gcgggcggtc gccgcaccga
    13501 gcaccgtcgt cggataccga tcgatggctt ggttgaacca cgtcccttcc accaccggga
    13561 cctgcagtgt ctccggcaat ccaggactgg cagccagaat cgagatgccg ccggtgctca
    13621 cctccggcat gcggtcgtgc cggtacaccg cacctggcac gcgcccgacg tgcgcgacct
    13681 gttgcacgcc aggcaaccgg ccgatcatcg ccggtgcttg cggcggcagg gtcgcggtgt
    13741 cgccaaatgc gttgttgcct ggccgcacgg tcaatagatt ggttcccagc tggtcgatct
    13801 gcttgagcag accggcctgg ctggacgcgg aaaccccgag cacggcgacc acacaggcga
    13861 taccgatcgc gatgccgagg cagctcaacg tggtccgcaa cggacgaccg cggatcccca
    13921 gcaggccaag ggaaattgca tcacgcgggc gcaatctcac tggatcactc catcctggat
    13981 gcggactgtc cgaggcatgc tcgcggccag ccggtcgtca tgcgtgatca ccacgaccgt
    14041 cgtcccagtc tcgttgagac gcctgagcag gccggccacc gcggcacccg accgggagtc
    14101 gaggtttccc gtgggttcat cggccagtac gacatccggt cgcccgacca ccgcacgagc
    14161 gatcgcgacc cgctggcact cgcctccgga aagctgcccc ggccgatgtt tcatccggtg
    14221 ggacatgccg acactcgcca acgcttccgc cgcacgttcc cggcgctgct gccgcggtgt
    14281 cccggtgtac agcagcccgg tggccacatt gtccattgcg gacagcgtcg ggttgaggaa
    14341 gaactgctgg aacacgaacc cgatgtggta cgccctgacc acggccagcc ggcggtccgg
    14401 cataccggtg atgtcctgcc cggcgacacg gaccgtgccc gcggtcggct gatccagcgt
    14461 tcccatgatc tgcaacaagg tcgtcttgcc tgagcctgag gggccgacaa ctgcgacgag
    14521 ttcaccggat cgcacgatca ggtcgatgtc ccggagcacg gtcaactctc cgtacttttt
    14581 cgtgaccttg tgtagctcaa gggtcatatc gtcggcacct ccacccgcat cccctcgacc
    14641 agtcccgggc tggtgatctc gacccggctg gcggtgaaca ggccgggctc gacctcgatg
    14701 gtgtgcctgc cgttctggtc gaccaccaca accgcgtacg cgccgcccgg cacgacagtc
    14761 agcgcttcga tcgggactgt gagcaccccc cgccgcgact cgccaggaaa gatcacggtg
    14821 accgggccct cgaacacccc gccgagctct gcctccgggc tcgtgatcag gatgtccacc
    14881 ccgatggtct gccgctcctg gttcgtgttc tgctgcccgt tctgctgcgg ttgggtggca
    14941 gtggactcga tggtcttgac cactccggtg accgatcggc cgccgaacag tcgcacctgg
    15001 acggtctgat ccaccgccgc catcgaacga tgccgccggt cgaggtccac gtgcacaccg
    15061 tgctcggtcc ccgtcccggt gacgagcgct tcacctggcc tggccatcgc accgaccaag
    15121 ccgttggttg ctgtcacccg caccggaccc gccgcgacga gtgcgtcccc tggctcgacc
    15181 gtgccggtct cggtgaggcc gagcgacttc tgccagcgct tcaccgcgtt cacggtcgcc
    15241 gaggtgtacg tgtcgtccgg ggtgaaggtc gcgtggccga gatcgacgag attgcgttcg
    15301 agttgccgga cgtcctcccc ttccacagca cggttcagcg gccggtagaa cggcaacgtg
    15361 ccgtagaaca acgggatcgg ccgctgatcg accgcgtaca cctgctgccc acgggagatc
    15421 acttggccaa cgccgggcat agccgtgacc gtgccttgcc gttgagcgac aagctggatc
    15481 gacccgacgt agccgagctg gcccggctgt tggatcgacg acaccaggtc gccgcgcgtg
    15541 accggcgccg tgggcagcgg tttctgctca gcctgcggct gggcttggct cgtgcatgcc
    15601 gtggcgagca ggacagtggc cactatccag cccctcactt gccgtttcct cccttgccgg
    15661 gcgggctgtc cagtgcttcg cgcatctggg gcggcagatg ctcgtcgcac gcttcgaacg
    15721 ccggttgcca cgcaggcgag tcgtagaggt tcttctcgat ggtgaacctg ttgtcgggcg
    15781 tcggatccgg catgtccaca ccgtgctccc gcatgcaccg cgcgaaagca agccattgct
    15841 cgggcgtgcc tttctggttc ggcacgcccg ccgcgaccat ggcgtcgttc agcggctgac
    15901 ggcactgctg ccggtcggtc tgatacccct gcgtacgccg ttcgtcctcg ggttcctgga
    15961 acaccggcag gccgtcctcg ttgaaggccg ggtcgggcac ttggtgtccg cggtctcgca
    16021 tgcactggct gaagccgacc gcggtccggc tgatctcctc ggatttcgca ggcttgaccg
    16081 gttccgtggt cgcctgacag ccggccatga cgacggccgc gatgatcaac atggcttttc
    16141 tcatgggccg caccctgctc gcgggcgcat caacgccgcg tgcgcgaaag tcttgaactc
    16201 gtcttgatcc gcccgggtgt ctactgggac gtatgcgtgt gcttgtcgtc gaggatgacg
    16261 ccgtgctggc tgaggcgatc gcccgtggcc tgcggcggca cgcgatgagc gtcgacgtgg
    16321 cagtcgatgg cgcgcgagcc ttggagtgcg cggcggtcac gcgatatgac gtggtcgtgc
    16381 tcgaccgtga cctgcctggt gtgcacggcg acgaggtctg cagacaactg accggcgaca
    16441 gcacccggat tctgatgctg acggccgctt cgaccgtgcg tgaccgggtc tccgggttga
    16501 acctcggcgc cgacgactac ctgccgaaac ctttcgcgtt cgacgagctg gtcgcccgtg
    16561 tgcacgcctt gctgcgtcgg tcagcgcccg cccgtgcccc ggtggtctcc cgcgccggga
    16621 tcacactcga cccggcgcag cgcgtggtgt tccgcgatgg ccggttcatt cgcttgtccc
    16681 ctaaggagtt cgccgtgttg tacgtcctgc tttcggcgga tggcgcggtg gtcagcgccg
    16741 aagagctgct cgaccgcgcg tgggacgagc acgccgaccc gttcaccaac agcatgcgca
    16801 ccacggtcgg gacgctgcgc aagaagctcg gcgaaccgcc tgtgatcggc acggtggtcg
    16861 gcgcgggata tcagatccga tgagactcac cgcgcgcacc cggctgactt tgctgttctc
    16921 cgcgttgatc gcgttctccg gcgctgtgtt ggcggtgatc gtcatcgtgc tcgcgttcac
    16981 gcccaaccgg gccaatgccg aacccaagat cccggcgaac aaggttgtcg tgatggagaa
    17041 gtcccagatc gaccagctcg gcgtggacat caaggcacag gcacgcaccg aactgctgga
    17101 ccggttgatg ctcggcgccg ggatcgggat cggcgtgctg accgtgggtt cagccgggct
    17161 tggctggcta cttgccggtc gggtgctgcg gccggtgcac gtcgtctccg gcaccgcacg
    17221 gcggctttcc cagcagaacc tgcacgaacg catcccggtc agcggtccgc aggacgaaat
    17281 gcgcgagctg gccgaaacct tcaacgacat gctggcccgt ctgcagcgat cgttcgatgc
    17341 ccaaagccat ttcgccgcca acgcggcaca tgagctacgc ggcccgatga ccacacagcg
    17401 aactctggtc gaggtcgccg cctgcgcgcc cgacgccccg cccccgctgc gcgaattggc
    17461 cagttcgctc ggcccagtgc tggaccgtca ggaacgtctg gtcaacggcc tgctggaact
    17521 cgcgtggagc gagcacggcg tgaccaaggt cgagcccgtg cgggtcgact cgcttgtccg
    17581 cgcgccgggt gcttcgctgt cgctgcaacc tttgaccgtg cgcggcgatc cgacgctgct
    17641 ggaccttatg gtggacaacc tggtccgcaa cgccttcacc cacggccggg aagtctgggt
    17701 cagcaccacg tcggactcgt tgtgcgtgga gaacaccggc gaagtggtgc cggctgagcg
    17761 gctcgccacc ttgaccgagc cgttccgccg gggcagtcag gaccgcttga acagcaacgg
    17821 aacgggtctc ggtctggcga tcgtcaacgc tgttgtccgt gcccacaacg cctctctcga
    17881 gctgacgccg cggcccgggg gcggaattcg cgcgacagtc cggtttccag ctggcaccat
    17941 gcggtgaatg gctcgcctgc gtgacattgt catcgactgc aagcaccccg cgtcgctcgc
    18001 ccggttctgg gcggccgtgc tggacgacta cgaaatcgcc ccttacgacg acgaggaact
    18061 agcccggctg cgaagtatcg gagtcgagtc gccggaggac gaccccactg tcctgctgca
    18121 acgccttgac ggcgcgccac ctcggatctt cctggtgctg gtgcctgagc cgaagaccgt
    18181 gaagaaccgc gtccacctgg acatcgacgg tgacgtcaac gcggtactgg cactcggcgc
    18241 gacactcgtc gcgaaacacg aaggtcatca cctcctcaac gacccggaag gcaacgagtt
    18301 ttgcgttatc ccgtgatcca cgaacacccg ttggcgtacg tcctcggcct tcaaggcatc
    18361 gcgttgctgc agggattcat cggtgagcac gaccgggact tcatcgaagc cagactcgcg
    18421 gagatccgtg agctgctgga caacgagcag ctcacccagg ctgtcgaggt cactccggtg
    18481 agcacagtgg acggttaccg gacctggtcg gccacgtacg acagtccgtc caacccggtc
    18541 ttcgagatgg atgtgcccat cctcaaggag atcctcgcgg acgtgcctgc gggtatggcg
    18601 ttggacgcgg cttgcgggac cggccggtac gcggaactcc ttgccgggca gggacaccgc
    18661 gtgatcggtg tggacagttc gccggacatg ctcgagcggg cccgcaaacg cttgccggac
    18721 agcgagttcc gcgaaggcac tctgcatcac ctgccggtcg acgaggtgga cctgatcctg
    18781 tgcgggctcg cgctgacgca caacccggac ctcgggccca ttttcgcgga gttcgccagg
    18841 gtgttgcggc ccggtgggca cctggtcgtc gtcgacatgc acccggacgc catcctgcgt
    18901 ggctccattc ccactgttcg cgggccgaag ggcgagccgt gccgggtcgt cacgtatcgc
    18961 cactcgatgg gtgactacct ccgcgcgtcg ctcagcaacg gcctcacggt ccggcgctgt
    19021 gaggaactgc ggagcgcctc gatgctcgag aagaccgaca gccccggtcc gtgggatgtc
    19081 tggccgtggt cgttggccgc gttggcgccg gaggccgcgt acgccgccac cggtccacag
    19141 atggtcatct ggcatttcca agccgatatc ttgcacacga tgtaatcgcg cgctagggtt
    19201 cggttatgac cgagccggac gccaggaacc tccttctgct cgacgagcag gcctgcttcg
    19261 cgttgtacgc ggcgtccagg gcggtcacgg acgtgtaccg gccactgctt gccgagctgg
    19321 acctgacata tccgcagtac ctcgtgatgc tggtgctgtg ggagcgggac aaccagccga
    19381 tcaagcagat cggtgccgcc ctacacctcg actacggcac cgtctccccg ctgctcaagc
    19441 ggctggaggc gcgtgggctg gtgcaacgca agcgacaggc ggacgacgag cgaagcgtcg
    19501 tggtgagcct gacgccggag ggtgtcgcga tgcgcgaacg cgcagtggcg atcccacccg
    19561 cgatcggatg cgcactgggc ctgaacaacc aggacctcgg tgtactcatg gatctgttgc
    19621 ggcgagtcac cacgtccgcc cggaccacag cacaagaagg agaacactga ccatgccaag
    19681 ccgcgacgcg accacccact gggaaggcga cctgcagacg ggtggcggca acgtcaccct
    19741 ggactcgtcc aacgccggac agttccgtgt caccttcccg gcccgcaccg gcgacccgga
    19801 gggcatgacc agcccggaag agctgatcgc cgcggcgcac tcgtcctgcc tggcgatgaa
    19861 cttcaccggc acggtgaaga aggcgggctt cacaccgggc actgtggacg tcagcgccga
    19921 ggtcacgctc ggaccggacc ccgagggcgg cttcaagctc accgagatcg cggtgacgct
    19981 ggtcgccaag gtcgacggcc tcgacaagga caagttcgcc gagctcgcgg cgaccgccga
    20041 gaagacctgc ccgatctcca aggcgctcgc gggcacgacc atcacgctgg acgcttcgct
    20101 cgcggagtag tccgacagtg gttaacgtca tgaatcatga cggtgagcag gcgtgaccta
    20161 ctcgtgggac tgggtgcggc catgaccggt ttcggcatgg ccgcaccgcc cgactgggac
    20221 cggttgcgca gacgactcgc cggacctctt tacctgccac aggatgctgg ctacgccgcg
    20281 gcacggcagg ggtacttcac aatccacgat ggacagcgcc cggccgccgt cgctcgctgc
    20341 acgcggatcg aggacgtcca ggcctgtgtg gaattcgcgg ccgccaccag gacaccggtg
    20401 agcgcacgca gcggaggcca cagctacgcc ggatactcca cacgagacgg cagcctggtc
    20461 gtggatctac gccagctcgc cggaatccag ctctacccgg acggcacggc cgtgatcggc
    20521 gctggcgctc agctgatcga cgtctatgcg acccttgctc aagcagggcg actgcttccc
    20581 ggcggaacct gcccttcagt gggcatcgcc ggactgacgt tgggcggcgg gatcggcgtc
    20641 acagcacgga agtacggcct gacgtgtgac cggcttgtgt ctgctcagat cgtcaccgcg
    20701 gacagcaggc tgcggactgt ttccgcggtg caggaacctg agctgttctg ggcgttgcgg
    20761 ggtggtggcg gcgggaactt cggcattgtc acgtcgttca ccttccagac tgcccccgct
    20821 actgacctga ccgtgttcgc actggagttc ccggccgccg cgctgcccgc tttgcttggc
    20881 ggctggcagt cttggcccgt acccgacgag gtgtggtcga atgtgagcgt tccaggcgat
    20941 ccacaggcca ccacatgggt cgacggatgc ttcgtcggtt cttcctcagg tgtccagcca
    21001 catctcgaca agctcacgcg actcgttggt acgcaacccc ttgcgcggat agtcaagcag
    21061 ttcagctact tcgacgcgat gcggtacttc gcgggatgct cggagctgtc gctgaaggag
    21121 tgccgtccca actggaccag cgacgctggc ctgctcgacc gcggcgctta cgtcgccact
    21181 tcgcgaatga tcggtgcacc actgcgtgat ccggccgcca cagcggctct gctgcgcagt
    21241 tctccggggc tgacaacgca gttcgacagc ttcggcggcg agatcgcccg tggccccgac
    21301 accgctttcc cataccggca aagcatcgcg agcatgcagg tcacgcacga gttcgacggc
    21361 acagcccggc aggccatcgc ccacgtccgc gacgaaaccg cgcgcgaatt cgggcagacg
    21421 ggctacatca actacatcga cccgcatatg cccaactggg cacaggcgta ctacggcagc
    21481 aacctcgcca agctccgcac gatcgcccgt cgctacgacc caggtcgggt cttcgcgttc
    21541 gcccaaggtc tcagttgacc tcaagcatgg ttgagctacc aggatcatgg catggacacc
    21601 gagatcgccg cgatcaagca ggtcatcgcc actgtggagc actcgcagca gaacgagctg
    21661 ccggacgagt tcgtgagcct gttccgagcc gacgccatct ggacaaccgg tcacggcaag
    21721 cgcctgaccg gcagagacga gatatccacc ttcacacaca aggttctgcc cggcgcgatg
    21781 cgcgactcga cctgcgccta cgaggtcgtc gacatcctgt tcatccggcc ggatgtcgcc
    21841 gccgtcaagg cgcgggcccg gtacctcact ctcgacgggc agcagatcgg taacgagggc
    21901 acgccgctgt acgtcatgtc caaggagaac ggcgagtgga agctcgtggc ctgccagaac
    21961 actgaagtcc ttgacttcga gtccacttga ggttccagga tggcggcatg cgaaaccaca
    22021 ccgccatctt cctgtcccag caagcccacc gggcccgcac accatggtcg aagggccgcg
    22081 accgcggcac cctttcggcc aggccgccgc ctagacgtcg aagaagaccg tctcgccctc
    22141 gccctgcagg cggatgtcga agcggtaacc gtcctcagtg ggctgggcga tcaacgtgtg
    22201 ccgtcgcgcg ggatccacac tggacagcac tggatccgca gggtcgtccg cgaaatagat
    22261 ccgggtgacc acgcggttca gcaggccacg ggcgaatacc gagacgtcga tgtgcggagc
    22321 ctgcccggga atcgcacccg gcaacagcgt caagatccag tagttgccgt ccacatcggt
    22381 cgggcagcgg ccgaaggcac ggaattcctt gcgcagcggg ccggacgggt cgtccgggtg
    22441 gtcgaagtgc ccgtccgggt cggcctgcca tgtctcgatc aacgcgtcgg gcacggggtt
    22501 tcccgcgccg tcgaaaaccg tgccgacgat ccggatcgcg ccgggggtgt cgagagggac
    22561 gacagtcggg ccgtcgggcc aag
//
