LOCUS       NZ_FWXV01000003        10375 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Kibdelosporangium aridum strain DSM 43828, whole genome shotgun
            sequence.
ACCESSION   NZ_FWXV01000003
VERSION     NZ_FWXV01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kibdelosporangium aridum
  ORGANISM  Kibdelosporangium aridum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Kibdelosporangium.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2017) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900176515.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:02:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,283
            CDSs (total)                      :: 11,193
            Genes (coding)                    :: 11,032
            CDSs (with protein)               :: 11,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 3, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 38 of 161
            Pseudo Genes (incomplete)         :: 135 of 161
            Pseudo Genes (internal stop)      :: 6 of 161
            Pseudo Genes (multiple problems)  :: 17 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:58:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 468359
            Orig. end                         :: 478734
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FWXV01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10375
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="7"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..10375
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10375
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5375](-)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5375)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     misc_feature    116..129
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.64"
                     /tool="antismash"
     gene            complement(196..759)
                     /locus_tag="B9C43_RS21170"
                     /old_locus_tag="SAMN05661093_04316"
     CDS             complement(196..759)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020177.5"
                     /locus_tag="B9C43_RS21170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04316"
                     /product="DUF1772 domain-containing protein"
                     /protein_id="WP_051895008.1"
                     /transl_table=11
                     /translation="MLAHQGAGQQAGPRSKAAAPLLYLATLTVGLMAGFFFAFAILVMP
                     SLAKVDDRSFVVAMQKINEGVQTGAFAFAFFGAFIFTGAAAIVHQRAGYRAAARWIFAA
                     MLLYVVALALTFGGNIPLNDKLAAAGDPAVIADFAAARAAFNEGTWNALNAARTIACML
                     SLLALVPAIALHGRANKALKTGIS"
     gene            complement(865..1518)
                     /locus_tag="B9C43_RS21175"
                     /old_locus_tag="SAMN05661093_04317"
     CDS             complement(865..1518)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013936.5"
                     /locus_tag="B9C43_RS21175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04317"
                     /product="hemerythrin domain-containing protein"
                     /protein_id="WP_084428622.1"
                     /transl_table=11
                     /translation="MTMSTENGVGGLPVHIHGFALMHVAMRRDARRIAKAAPHVTRANA
                     APVASWFDQLREVIEWHHRTEDDVLFPALRKRVADFAEKEKGLAHDHTELDQSMLEVSK
                     ALHGDVSAAPAAAEKFENILLEHLKVEEPIVFPVFVDDLTRQQYLDIENQVMRSAGPGM
                     RAFLFPWLFDGVDKRTAAVAAAVSIPPPVRLIGNTVLTWRYERMIAPVVDLGRR"
     gene            complement(1515..2333)
                     /locus_tag="B9C43_RS21180"
                     /old_locus_tag="SAMN05661093_04318"
     CDS             complement(1515..2333)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635300.1"
                     /locus_tag="B9C43_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04318"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_084428623.1"
                     /transl_table=11
                     /translation="MSDKTTLVLGGTGKTGTRVTARLEALGVQVRIGSRTAAQPPFDWD
                     DRGTWGPVLDGVDKVYVVYSPEIAFPGAAETIADFCAAAVDAGVQRLVLLSGRGDEVHA
                     GGSEQAVRESGAEWTILQAAWFNQNFSESFMLEPVRHGVIELPASDVAEPFIDAEDIAD
                     VAVAALTTDHHLGQTYELSGPRLLTFGDAAAEIGAATGKEVSYVPMTFVEYAQMLRQHG
                     LPLAYVEMFRKVLDGRNSYLSDGVQRALGREPRDFGDYARKTAETGIWSG"
     misc_feature    complement(1791..1793)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2395..3090)
                     /locus_tag="B9C43_RS21185"
                     /old_locus_tag="SAMN05661093_04319"
     CDS             complement(2395..3090)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012444.5"
                     /locus_tag="B9C43_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04319"
                     /product="indole-3-glycerol phosphate synthase"
                     /protein_id="WP_084428624.1"
                     /transl_table=11
                     /translation="MTFVDALTGADRPVIMELKRRDPNGEDLFGDRSIAEIVAEYEAAG
                     APCISVVTGRWFGGTDSMLSEVASLTDRPVLQKDFITRRDQLLKARDLGASAVLLTAGL
                     LPRSSMPTLINGSLELGLTPFVEVTDEAEIEVLPSAEHCVVAVNNKDIKNRERGLGDLD
                     RSVRLLPALAASGTRCPVSASGITKPQDADRLLAEGYRGLLIGTGLLRTTSLTGWLAEL
                     DTLRTLRAP"
     gene            complement(3087..3809)
                     /locus_tag="B9C43_RS21190"
                     /old_locus_tag="SAMN05661093_04320"
     CDS             complement(3087..3809)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012900.5"
                     /locus_tag="B9C43_RS21190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04320"
                     /product="hypothetical protein"
                     /protein_id="WP_084428625.1"
                     /transl_table=11
                     /translation="MKIGFKRNKADRKLLKVCGATTKADVELLAGAGADLVGLWHGVAD
                     GPAEVSVEQVTTLAEAARATGRLEPTLVTFLSDVEVLRQIIDRTGISWIQLHAYQMPAM
                     IRALRQSVAADLTIVKVLHLKNGKCLERPLIKAYENAGVDVFLLDVVTSDGQIGSTGQR
                     LQAGDVADLVPSFSKPFLLAGGISAHNSGDYETVVRHPQFQGIDVDTGARNHSGRFERK
                     NITDISRGWRTARYVEVA"
     misc_feature    complement(3636..3638)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3806..4948)
                     /locus_tag="B9C43_RS21195"
                     /old_locus_tag="SAMN05661093_04321"
     CDS             complement(3806..4948)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646413.1"
                     /locus_tag="B9C43_RS21195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04321"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_084428626.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.2e-17, bitscore:
                     59.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.8e-26, bitscore:
                     86.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.6e-34, bitscore:
                     113.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDWNEDQIELREGLSAWHEAFSADHVENDEGSVFSWQKWKLVAE
                     SGILSLPFDERWGGLGQDLLTTMYVLEGLGEGCRDGGLNFSITTTICSVGVPVERFGSP
                     ALKDKYLPQIIAGDAIGAHAITEPAGGSAALQMRTKADRDGDTFILNGSKTFVSNGPIA
                     DLFMVYAKTHPDGGPLGITAFLIEKDTPGFEVGNPIKKMGLRTSPLSELYFDDCRIPAS
                     QVCGRVGGGFLVLDHVMKREILYSFIVNVGEMQHRLGKVVEYAKERLQFGKPIASYQAV
                     ANKIVDMKIKLETSRKWLYDTAEKLVRGDNVTTDMAIAKLLTSQANLDTSLAAVQIFGG
                     NGYMAEYGLEKEVRNAVAGTIYSGTNEIQYNRIASMLGLS"
     gene            complement(5001..5375)
                     /locus_tag="B9C43_RS21200"
                     /old_locus_tag="SAMN05661093_04322"
     CDS             complement(5001..5375)
                     /GO_function="GO:0033990 - ectoine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004559775.1"
                     /locus_tag="B9C43_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04322"
                     /product="ectoine synthase"
                     /protein_id="WP_033381306.1"
                     /sec_met_domain="ectoine_synt (E-value: 1.3e-31, bitscore:
                     105.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIRSIDEVKTVEWGNGLSRRFLLEADGMGYTLTDTLVRAGTKSH
                     LEYRNHLEACYCIEGSGEVIDTEGNSFPITPGVMYALDKHDPHWLVASPHEDLRLVCMF
                     TPALRGDEAHNLDTDEFSEY"
     gene            complement(5378..6196)
                     /gene="trpA"
                     /locus_tag="B9C43_RS21205"
                     /old_locus_tag="SAMN05661093_04323"
     CDS             complement(5378..6196)
                     /EC_number="4.2.1.20"
                     /GO_function="GO:0004834 - tryptophan synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpA"
                     /inference="COORDINATES: protein motif:HMM:NF012511.5"
                     /locus_tag="B9C43_RS21205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04323"
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="WP_033381307.1"
                     /transl_table=11
                     /translation="MAEFFDQIADGEPGLALFLNAGDPSLDILADLVFMLDDAGVDCLE
                     LAVPFPGSVTDGPVIRRSHERALALGVGLDEVLTFISNVRPKLHRLRIALLADWSYSIK
                     SRPMAEVVGDIAEAGADGLLLHAVPPRVRPGYYQATKDAGLPVVTTCYHKVSTQQVMAE
                     AAEHASAYLYLVAQYGRSGTAPADGFADLAGTIAELRLDTHVPIAVGFGVKTRADVTTV
                     HALGADAVIVGSAGVARVEEALAYNRDVVKQFEDFVRSVHPAHTLGTLRS"
     gene            complement(6189..7241)
                     /locus_tag="B9C43_RS21210"
                     /old_locus_tag="SAMN05661093_04324"
     CDS             complement(6189..7241)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012800.5"
                     /locus_tag="B9C43_RS21210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04324"
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="WP_033381308.1"
                     /transl_table=11
                     /translation="MHPAIISLLDHRPNIERETWRSLWDQLGAGDLDRGEAVALLASLA
                     TRLPDHDSLRNLLASLNERREPVTTSWPGTVNIVGTGGGPRTFNISTASAFVAASLGVK
                     VVKTGSRAYTSSVGSIDLLERIGVGLTRSYRHTEDTLDKYGIAFAGPFVYPSELLRMAR
                     VIMPLGLKPFGRFVNALGPFLAALPVAAQVTGVSVHAPQPELRRLAAGIKNRKIWLCMN
                     DSGADELLGFADNVIYTNDDTSMIRLWAGRFTSDKGTFEDLAPARDLDLVADHFLAVIS
                     GEAGPVVTETISLNAAALAVATGQIEDWSDAFDAARQAVTSGAARSLVDKMRSPQERKL
                     TLVRKAVSNG"
     misc_feature    complement(7173..7175)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7248..7508)
                     /locus_tag="B9C43_RS21215"
                     /old_locus_tag="SAMN05661093_04325"
     CDS             complement(7248..7508)
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (18-69). E-value: 2.6e-07.
                     Score: 22.9. Matches aSDomain:
                     nrpspksdomains_B9C43_RS21215_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147: putative acyl carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680900.1"
                     /locus_tag="B9C43_RS21215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04325"
                     /product="acyl carrier protein"
                     /protein_id="WP_033381309.1"
                     /sec_met_domain="PP-binding (E-value: 1e-05, bitscore:
                     21.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding_2 (E-value: 0.0081, bitscore:
                     12.3, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNVDAIKKFVIDEFLPDVAPEDLAVDYDLLADGVIDSLGLLKLI
                     AWVEDHFALSVHDTDLDPNNFRSVQAIDEFIEDARSQVAGS"
     aSDomain        complement(7302..7454)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS21215_PP-binding.1"
                     /evalue="2.60E-07"
                     /label="B9C43_RS21215_PP-binding.1"
                     /locus_tag="B9C43_RS21215"
                     /protein_end="69"
                     /protein_start="18"
                     /score="22.9"
                     /tool="antismash"
                     /translation="VAPEDLAVDYDLLADGVIDSLGLLKLIAWVEDHFALSVHDTDLDP
                     NNFRSV"
     gene            complement(7505..8995)
                     /locus_tag="B9C43_RS21220"
                     /old_locus_tag="SAMN05661093_04326"
     CDS             complement(7505..8995)
                     /NRPS_PKS="Domain: AMP-binding (8-393). E-value: 3e-72.
                     Score: 235.4. Matches aSDomain:
                     nrpspksdomains_B9C43_RS21220_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.5"
                     /locus_tag="B9C43_RS21220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04326"
                     /product="AMP-binding protein"
                     /protein_id="WP_084428627.1"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-72, bitscore:
                     240.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTFKERFLSQVSRRPGAPALVWHGEVTTYGDLYELADKARARLE
                     WSNLEPGEPIGLLVKKSPQAVALVLGAILSGRRFLLPSPALANSALTSLFAQAGCQAVF
                     APEGEPEFSPDPEADTTAAEATDVHDVQFMLTTSGSTGLPKIVPLPRQGIDRFIEWAGA
                     EFDIRPGRTVLNYAPLNFDLCLLDIWTTLALGGQVVLVDPDYAANGRHLLDMLVRHEVN
                     IIQAVPMFFGLLLDIVQPAVDRLESVDRVMFTGDAIPDRTLAELPRLFPKASLHNIYGC
                     TETNDSFIHHLGNGDTAVRPPVSIGKPLPGVHTLILTGEGTVLDGPGTGELYVSTPFQA
                     AGYLDRTRHTDKFVPHPAAADDRPWFRSGDLVRREEDGRVFLIGRSDFQVKVRGVAINT
                     AEVEHVLLEHPAVLEAAVVAVPDPIAGRRLVCAVHRAADSKLNSLTLRQHCARRLPQAA
                     IPSAMHIVDEPLPKTSTGKVDRNAFAKPVEKTSKGRTS"
     CDS_motif       complement(7787..7849)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9C43_RS21220_0003"
                     /evalue="4.90E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="B9C43_RS21220"
                     /protein_end="403"
                     /protein_start="382"
                     /score="22.2"
                     /tool="antismash"
                     /translation="IGRSDFQVKVRGVAINTAEVE"
     aSDomain        complement(7817..8971)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9C43_RS21220_AMP-binding.1"
                     /evalue="3.00E-72"
                     /label="B9C43_RS21220_AMP-binding.1"
                     /locus_tag="B9C43_RS21220"
                     /protein_end="393"
                     /protein_start="8"
                     /score="235.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LSQVSRRPGAPALVWHGEVTTYGDLYELADKARARLEWSNLEPGE
                     PIGLLVKKSPQAVALVLGAILSGRRFLLPSPALANSALTSLFAQAGCQAVFAPEGEPEF
                     SPDPEADTTAAEATDVHDVQFMLTTSGSTGLPKIVPLPRQGIDRFIEWAGAEFDIRPGR
                     TVLNYAPLNFDLCLLDIWTTLALGGQVVLVDPDYAANGRHLLDMLVRHEVNIIQAVPMF
                     FGLLLDIVQPAVDRLESVDRVMFTGDAIPDRTLAELPRLFPKASLHNIYGCTETNDSFI
                     HHLGNGDTAVRPPVSIGKPLPGVHTLILTGEGTVLDGPGTGELYVSTPFQAAGYLDRTR
                     HTDKFVPHPAAADDRPWFRSGDLVRREEDGRVFLIGRSDFQVKVR"
     CDS_motif       complement(7943..8011)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9C43_RS21220_0002"
                     /evalue="2.30E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="B9C43_RS21220"
                     /protein_end="351"
                     /protein_start="328"
                     /score="13.6"
                     /tool="antismash"
                     /translation="TGELYVSTPFQAAGYLDRTRHTD"
     CDS_motif       complement(8549..8596)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9C43_RS21220_0001"
                     /evalue="1.00E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="B9C43_RS21220"
                     /protein_end="149"
                     /protein_start="133"
                     /score="12.2"
                     /tool="antismash"
                     /translation="MLTTSGSTGLPKIVPL"
     gene            complement(8995..9825)
                     /locus_tag="B9C43_RS21225"
                     /old_locus_tag="SAMN05661093_04327"
     CDS             complement(8995..9825)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013722.5"
                     /locus_tag="B9C43_RS21225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05661093_04327"
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="WP_143446489.1"
                     /transl_table=11
                     /translation="MTPTLSTRTVRKVTADEIATYREVVRSGLTPSDGKASPLHAFVLA
                     SPVIDESVGLIGATTADGSQLGRVHLSQEIHVQRPIRADEPVTVALDVVGTRKSLKGVQ
                     VAMKVALLGEDGEQFAELITGAMLVGAVTPDTFGQLPPHPGKGSTAEPTVVAQSIARDT
                     VTKYAYASGDLNPIHLDDNAAKDAGFENGVIAHGMSVLAVVTEEVIDRYGAGDASRVRS
                     VGARFSSAVLPDTPLEIVLQKDDAESSIGTAFVRFACKTPTGPALKSGWVELGD"
ORIGIN
        1 gttgattttc tgcatcacgt cgacgaacgt gcggtcatcc gtaccgcgca gactgaccat
       61 caccgaaatg gagtaggtgt agaaaaagcc ggacaccagt ccaagcagga gcgttgtcac
      121 gatcagtgac gcggccctga ccacttccat tgttgttcct ccctgccccg cgtgatccca
      181 gtcgaacgga cagtatcagg aaatgcccgt tttgagagcc ttgttcgcgc gtccatgtag
      241 tgcgatcgcg ggcaccaacg ccaacaacga caacatgcac gcgatcgtgc gtgccgcgtt
      301 aagagcgttc caggtgcctt cgttgaacgc ggcgcgcgcg gcagcgaagt cggcgatgac
      361 ggcgggatca cccgcggcag ccagtttgtc gttgagagga atgtttccgc cgaacgtcag
      421 cgcgagtgcg accacataga gcagcatggc ggcgaagatc cagcgtgcgg cggcgcggta
      481 gcccgcccgc tggtgcacga tcgcggcggc accggtgaag atgaacgcgc cgaagaaggc
      541 gaacgcgaac gcgccggtct gcacgccctc gttgatcttc tgcatggcca cgacgaacga
      601 ccggtcgtcg accttggcca gcgacggcat gaccaggatc gcgaaggcga agaagaagcc
      661 ggccatcagt ccaactgtga gggtggccag gtacaacagc ggagcggcgg ccttgctgcg
      721 tggcccggcc tgctggccgg cgccttggtg agcgagcatc ggactcgtcc ttctctctgg
      781 tgtggactca ttggtagcag gcaagccggg cggaaccgtc cagtcttccc tcgatcgggg
      841 tgaacagttc accggaacag ccgatcaacg cctgccgaga tcgacgaccg gtgcgatcat
      901 gcgctcgtag cgccaagtca gcacagtgtt gccgatcaga cgcaccggtg gcgggatgga
      961 caccgcggcg gccaccgcgg cggttcgctt gtccacgccg tcgaacagcc aggggaacag
     1021 gaaagcccgc atgccgggac ccgcgctgcg catcacctga ttctcgatgt ccagatactg
     1081 ctggcgcgtc aggtcgtcga cgaacaccgg gaagacgatc ggttcttcca ccttgaggtg
     1141 ctcgagcagg atgttctcga acttctcggc cgccgccggg gccgcggaca catcgccgtg
     1201 caaggctttg gagacctcca gcatcgactg gtcgagctcg gtgtggtcgt gcgcgagccc
     1261 tttttccttc tccgcgaagt ccgccacccg cttgcgcagc gcggggaaga gcacatcatc
     1321 ctctgtccgg tggtgccact cgatcacctc acgcaactgg tcgaaccacg aagccaccgg
     1381 ggctgcgttg gcacgcgtca catgaggcgc tgccttcgcg atcctgcgtg cgtctctgcg
     1441 catcgccacg tgcatcaaag cgaagccatg gatgtgcacc ggcaggccgc cgacgccgtt
     1501 ctctgttgac atagtcatcc cgaccagatc cccgtttccg cggttttccg cgcgtagtca
     1561 ccgaaatccc ttggctcgcg accgagcgcc cgctggacgc cgtcgctgag gtacgagttg
     1621 cgtccatcaa ggactttccg gaacatctcc acataggcca gtggcaggcc gtgttgcctg
     1681 agcatctgcg cgtactcgac gaacgtcatc ggcacgtaac tgacctcctt gcccgtcgcc
     1741 gcaccgatct ccgcggccgc gtcgccgaaa gtcagcagcc gcgggccgga taactcgtac
     1801 gtctgcccca ggtggtggtc cgtggtcaac gcggcgaccg cgacatccgc gatgtcctcg
     1861 gcgtcgatga acggctcggc gacgtcactg gcgggcagct cgatcacgcc gtgcctgacc
     1921 ggctcgagca tgaagctctc gctgaagttc tggttgaacc acgcggcctg caggatcgtc
     1981 cactcggcgc cgctttcccg caccgcttgt tcgctgccgc cggcgtgcac ttcgtcgccg
     2041 cggccggaca acaacaccag ccgctgcacg cccgcatcga ctgcggcggc gcagaaatcg
     2101 gcgatcgtct cggccgcgcc gggaaaggcg atctccggcg agtagaccac gtacaccttg
     2161 tcgaccccgt cgagcacagg cccccaggtg ccccggtcgt cccagtcgaa tggcggctgc
     2221 gcggcggtcc gggatccgat ccgcacttgg acaccgagcg cttccagcct tgctgtcacc
     2281 cgggtgcccg tcttgccggt cccgccaagc accaaggtcg tcttgtcgct cataacactc
     2341 ctaggcccgg gagacaggtg tcgtcccggg ccgctagtca gtaatccaca agaatcacgg
     2401 cgcgcgtaga gttcgtaggg tgtcgagttc ggccagccag ccggtcagac tggtggtacg
     2461 caacaggccc gtcccgatca gcagtccgcg gtagccctcg gcgagcaacc ggtcggcgtc
     2521 ctggggcttg gtgatcccgc tcgcgctgac cgggcagcgg gtcccgctcg ccgccagcgc
     2581 tggcagcaac cggacactgc gatcgagatc ccctaggcca cgctcccgat tcttgatgtc
     2641 cttgttgttg acggcaacaa cgcagtgctc cgcacttggc aacacctcga tctccgcctc
     2701 gtcggtcact tcgacgaaag gagtcagtcc cagctcgagg ctgccgttga tcagcgtcgg
     2761 catgcttgag cgcggcaaca ggcccgctgt caacaagacc gctgacgcgc caaggtcacg
     2821 ggccttcagc agttggtccc gccgcgtgat gaagtccttc tgcagcaccg ggcggtcggt
     2881 gagcgacgcg acctcgctga gcatcgagtc cgtgccgccg aaccaccgcc cggtgaccac
     2941 ggagatgcac ggcgcgcccg cggcctcgta ttcggccacg atctcagcga tcgacctgtc
     3001 gccgaacagg tcttcgccat tcgggtcgcg tcgtttcaac tccatgatca ccgggcggtc
     3061 cgccccggtg agcgcatcga cgaaggtcat gcgacctcca catacctggc ggtacgccaa
     3121 ccgcggctga tgtcggtgat gttcttgcgc tcgaaccggc cggagtggtt gcgagcaccc
     3181 gtgtccacgt cgatcccctg gaactgcggg tgccgcacga cggtctcgta gtccccgctg
     3241 ttgtgcgccg agatcccgcc tgccagcagg aaaggcttcg agaagctcgg caccaggtcc
     3301 gcgacgtctc ctgcctgcag acgctgcccg gtgctgccga tctggccgtc ggaggtcacc
     3361 acgtcgagca ggaacacgtc cacgcccgcg ttctcgtacg ccttgatcaa cgggcgttcc
     3421 aggcacttgc cgttcttcag gtgcagcacc ttcacgatgg tcaggtcggc ggccacggac
     3481 tggcgcagcg cccggatcat cgcgggcatc tggtaggcgt gcagctggat ccaggagatc
     3541 ccggtccggt cgatgatctg ccgcagaacc tccacatcgg acaagaatgt gacgagtgtc
     3601 ggttcgaggc gaccagtggc cctggccgcc tcggctaacg tggtgacttg ttcgacggac
     3661 acttcggccg gtccgtcggc caccccgtgc cacagtccga ccaggtcggc gcccgcgccg
     3721 gcgagcagct cgacgtccgc cttcgtggtc gcgccacaca ctttcagcag tttgcgatcg
     3781 gccttgttgc gcttgaatcc gattttcatg acagccccag catggatgcg atccggttgt
     3841 actggatttc gttggtcccc gagtagatcg tgcccgcgac ggcgttgcgc acttccttct
     3901 caaggccgta ttcggccatg tagccgttgc cgccgaagat ctgcacggcc gccaggctcg
     3961 tgtccagatt ggcctgactg gtcagcagtt tcgcgatggc catgtcggtg gtcacgttgt
     4021 caccgcggac cagcttttcc gcggtgtcgt acaaccactt gcgcgaggtc tccagcttga
     4081 tcttcatgtc gacgatcttg ttggcgacgg cctggtagct cgcgatcggc ttgccgaact
     4141 gcaggcgctc tttggcgtac tcgacgactt tgccgagccg gtgctgcatc tcgccgacgt
     4201 tgacgatgaa cgagtacagg atctcgcgct tcatcacgtg atccagtacc aggaacccgc
     4261 caccgacccg gccgcagacc tgggacgccg ggatccggca gtcgtcgaag tacagttcgg
     4321 acagtggcga tgtgcgcagg cccatcttct tgatggggtt gccgacctcg aagcccggtg
     4381 tgtccttctc gatcaggaac gccgtgatac caagcggtcc gccatccgga tgggtcttgg
     4441 cgtacaccat gaacaggtcc gcgatcggac cgttgctgac gaacgtcttg ctgccgttga
     4501 ggatgaaggt atccccatcc cggtcggcct tggtgcgcat ctgcaacgcg gccgatccgc
     4561 ctgccggttc ggtgatcgcg tgcgcgccga tggcgtcacc cgcgatgatc tggggcaggt
     4621 acttgtcctt gagcgcgggc gaaccgaagc gctcaacggg gactccgaca ctgcagatgg
     4681 tcgtggtgat cgagaagttc agcccgccgt cgcggcaccc ctcaccgagt ccctccagca
     4741 cgtacatcgt ggtgagcaga tcctggccga gcccgcccca ccgttcgtcg aacggcaggc
     4801 tgagaatccc cgactcggcg accagtttcc acttctgcca cgagaacacg ctgccctcgt
     4861 cgttctcgac gtgatcggcc gagaaggcct catgccacgc ggacaggcct tcccgcagct
     4921 cgatctggtc ttcgttccag tcgatcatca ctcgccccta agcaaccctc ttgggcgcat
     4981 ggcccaagag ggtgttcggc tcagtactcg gagaactcgt cggtgtcgag gttgtgcgcc
     5041 tcgtcgcccc gcagggccgg ggtgaacatg cacaccaggc gcaggtcttc gtgcgggctg
     5101 gcgaccagcc agtgcgggtc gtgcttgtcc agcgcgtaca tcacgccggg ggtgatcggg
     5161 aaggagttgc cctcggtgtc gatcacttcg ccggatccct cgatgcagta gcacgcttcg
     5221 aggtggttgc ggtactccag gtgcgacttg gtgcccgccc ggacgagggt gtcggtcagc
     5281 gtgtagccca tgccgtcggc ctcgagcagg aagcgccggg acagcccgtt gccccattcg
     5341 acggtcttca cttcgtcgat gctgcgaatg atcatggtca actccttagt gtgccgagag
     5401 tgtgagcggg gtggaccgac cggacgaagt cctcgaactg cttgacgacg tcccggttgt
     5461 acgcgagggc ttcttcgacc cgcgccactc ccgcggagcc gacgatcacc gcgtccgccc
     5521 cgagggcgtg cactgttgtg acgtctgccc gcgtcttgac tccgaacccg acggcgatcg
     5581 gcacgtgcgt gtccaaacgc aactcggcga tcgtgcctgc caggtcggcg aacccgtcgg
     5641 ccggcgcggt tccgctgcgg ccgtactggg cgaccaggta caggtaggcc gaggcgtgtt
     5701 cggcggcctc ggccatcacc tgctgggtgg agaccttgtg gtagcacgtg gtgacgaccg
     5761 ggaggcccgc gtccttggtg gcctggtagt acccgggtcg cacgcgcggt gggacggcgt
     5821 gcagcagcag gccgtccgcg cctgcttcgg cgatgtcccc gacgacctcg gccatcggcc
     5881 tgctcttgat cgagtagctc cagtcggcga gcaacgcgat ccgcagccgg tgcagcttcg
     5941 gccggacatt cgagatgaag gtgagtactt cgtccaggcc gacgccgagc gcgagcgctc
     6001 gttcgtgcga acgccggatg accgggccgt cggtgaccga gccggggaag ggcacggcca
     6061 gctcaagaca gtccactccg gcgtcgtcga gcatgaacac gaggtccgcc agtatgtcca
     6121 gcgacgggtc gcccgcgttg aggaacaacg ccagtcccgg ctcgccgtcg gcgatctggt
     6181 cgaagaactc agccattgga taccgccttg cgtacgaggg tgagcttgcg ctcctgcggc
     6241 gaccgcatct tgtccacaag ggaacgtgcg gcaccgctgg tgactgcttg ccgcgcggcg
     6301 tcgaaggcgt ccgaccagtc ctcgatctgg ccggtcgcga cggccagcgc cgcggcgttg
     6361 aggctgatcg tctcggtcac gaccggaccg gcctcgccgg agatcaccgc gaggaagtgg
     6421 tcggcgacca ggtcgagatc gcgcgccggg gccaagtcct cgaaagtgcc cttgtcggag
     6481 gtgaaccggc cggcccacag ccggatcatg ctggtgtcgt cgttggtgta gatcacgttg
     6541 tcggcgaagc cgagcagctc gtcggcgccg gagtcgttca tgcacagcca gatcttgcgg
     6601 ttcttgatgc ccgcggcgag cctgcgcaac tccggctgtg gtgcgtgcac ggacactccg
     6661 gtgacctgtg cggcgaccgg cagggccgcg aggaacgggc caagcgcgtt gacgaaccgg
     6721 ccgaacggct tgagccccaa cggcatgatc acccttgcca tccgcagcag ctcggacggg
     6781 tagacgaacg gtcccgcgaa agcgatcccg tacttgtcca aagtgtcctc ggtgtgccgg
     6841 tacgagcggg tcaggccgac accgatgcgc tcgagcagat cgatcgaccc gacactgctc
     6901 gtgtacgccc gtgacccggt cttgacgacc ttgacaccca gcgacgcggc cacgaaggcc
     6961 gacgccgtcg agatgttgaa agtccttggc ccgccgccgg tcccgacgat gttcacggta
     7021 cccggccagc tggtggtgac cggctcacgc cgttcgttca acgatgccaa caggttgcgc
     7081 agcgagtcgt ggtcgggcag ccgggtggcc agcgaggcca gcagggcgac ggcttcccct
     7141 cggtcgaggt cgcctgcgcc cagctggtcc cataacgacc gccaggtctc ccgctcgatg
     7201 ttcgggcggt gatccagcag ggagatgatc gcggggtgca cggcgtctca gctccctgcc
     7261 acctggctgc gtgcgtcctc gatgaactcg tcgatcgcct gcacgctgcg gaagttgttc
     7321 gggtcgaggt cggtgtcgtg caccgacaac gcgaagtggt cctccaccca cgcgatcagc
     7381 ttcagcaggc cgaggctgtc gatcacgccg tcggccagca ggtcgtagtc gaccgccagg
     7441 tcctcggggg ccacgtcggg caggaactcg tcgatgacga acttcttgat ggcgtctacg
     7501 ttgctcatga cgtccttcct ttactggtct tctcaactgg cttggcgaag gcgttccggt
     7561 cgaccttgcc ggtcgaggtc ttcggcagcg gctcgtcgac gatgtgcatg gccgacggaa
     7621 tggccgcctg gggaagacgt cgtgcgcagt gctggcgcaa cgtgaggctg ttcagcttgc
     7681 tgtcggcggc ccggtgcacc gcgcacacca atctccggcc cgcgatcggg tccggcacgg
     7741 cgacgaccgc cgcctccagc accgcggggt gttcgagcag gacgtgttcg acctcggcgg
     7801 tgttgatcgc gaccccgcgg accttgacct ggaagtcgct gcgcccgatc aggaagaccc
     7861 ggccgtcttc ctcgcgtcgc accaggtcgc cggagcggaa ccacggccgg tcgtcggcgg
     7921 cggccgggtg cggcacgaac ttgtccgtgt gccttgtccg gtcgagatat ccggctgctt
     7981 ggaatggcgt cgagacgtag agctcgcccg ttccgggtcc atcaaggaca gtgccttcgc
     8041 cggtcaggat gagcgtgtgc acgccaggca acggttttcc gatggacacc ggcggccgca
     8101 cggctgtgtc accgttaccg aggtggtgga tgaagctgtc gttggtctcg gtgcacccgt
     8161 agatgttgtg cagcgaggct ttcgggaaaa gccggggcag ctcggcgaga gtacggtccg
     8221 ggatcgcgtc accggtgaac atcacgcggt ccacgctctc cagccggtcc accgcgggct
     8281 gcacgatgtc cagcagcagg ccgaagaaca tcggcacggc ttggatgatg ttgacttcgt
     8341 ggcgcaccag catgtccagc aggtgcctgc cgttggcggc gtagtccggg tcgacgagca
     8401 cgacctggcc gccgagcgcg agcgttgtcc agatgtccag caggcacagg tcgaagttca
     8461 gcggcgcgta gttcagcacg gtccgccctg gccggatgtc gaactccgcg cccgcccact
     8521 cgatgaaccg gtcaatcccc tgccgcggca gcggaacgat cttcggcaag ccggtggatc
     8581 ccgatgtggt cagcatgaac tggacgtcgt gcacatcggt tgcttcggct gccgtcgtgt
     8641 cggcctcggg atctggcgag aattccggct cgccttctgg cgcgaaaaca gcctggcagc
     8701 cggcctgcgc gaacaggctc gtcaacgccg agttggccag tgcgggcgac ggcagcagga
     8761 accggcggcc gctcaggatg gcaccgagca cgagcgccac ggcctgcggg gacttcttga
     8821 ccagcagtcc gatcggctcg cccggctcga ggttcgacca ctcgagccgg gcccttgcct
     8881 tgtcagcgag ttcgtagagg tcgccgtacg tggtgacctc gccgtgccag accagcgcgg
     8941 gtgcgcctgg tctgcggctg acctgggaga ggaacctctc cttgaacgtg gtcatcagtc
     9001 ccccagctca acccagccgc tcttgagagc gggaccggtc ggcgtcttgc atgcgaaccg
     9061 cacgaaggct gtgccgatgc tcgactctgc gtcgtctttc tgcagcacga tttccagcgg
     9121 tgtgtccggc aggacggctg acgagaaacg ggctccgacg ctccgtaccc ggctggcgtc
     9181 gccggcgccg taccggtcga tgacttcctc ggtcacgacc gccagcacgc tcataccgtg
     9241 ggcgatcacg ccgttttcga agcccgcgtc tttggcggcg ttgtcgtcca ggtgaatcgg
     9301 gttgagatca ccggaggcgt aggcgtactt cgtcacggtg tcgcgtgcga tcgactgcgc
     9361 cacaacggtc ggctcggccg tgctgccctt gccgggatgc ggcggcagct ggccgaaggt
     9421 gtccggggtg accgcgccca cgagcatcgc accggtgatg agctcggcga actgctcgcc
     9481 gtcctcgccg agcagcgcga ccttcatcgc gacctggacg cccttgaggc tcttgcgggt
     9541 gccgacgacg tccagcgcga ccgtgaccgg ctcgtccgcc ctgatcggcc gctggacgtg
     9601 gatctcctgg gagaggtgga cccggccgag ctgcgagccg tccgcggtgg tcgcgccgat
     9661 cagcccgacg gactcgtcga tcaccggcga ggccagcacg aacgcgtgca gcggggaagc
     9721 cttcccgtcg ctgggcgtca gtccacttcg gacaacctcg cggtaggtcg cgatctcgtc
     9781 agcggtcacc ttgcggactg ttctcgtgga cagggttggg gtcataccgg cgtcaccacc
     9841 agacaggcgt tgtggccccc gaaaccgaac gagttcgaca acgcgggccc ggccgtcacc
     9901 ttgcgtggct tgccgtgcac gacgtcgatc tgcattcccg gttcgaggtg ctcatggttt
     9961 gcggttggcg gcaccacgga ctcgcgcatg gccatcaccg tggcgatcag ctcgaccgag
    10021 ccagcggctc cgatcaggtg cccgatgacg cccttcgacg aggtcaccgg cggaccgtcc
    10081 ggcccgaaaa ccttgtgcag ggcgaccgct tcggcacggt cgttgtgcgg cgtggacgtt
    10141 ccgtgcgcgt tgacgtgcac gatgtccctc ggctcgaggc cggcgctctt gatggcgctg
    10201 gtcatcgcgg tgaccgcacc ggcgccgtcc gccgcgggca tcgaaaggtg aaaagcgtcg
    10261 cttgtggccg cgtaaccagc gatttcggcg tacagccgcg cgccccgcgc ccgagcgtca
    10321 tcggcccgtt ccagcacgac gaaaccggcg ccctccccca tcacgaaccc gtcgc
//
